ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0030695	GTPase regulator activity	203/4842	489/18639	0.415132924335378	1.59803027193042	2.65820092594055e-14	2.29798153189117e-11
GO:0060589	nucleoside-triphosphatase regulator activity	203/4842	490/18639	0.414285714285714	1.59476898566118	3.38935329187488e-14	2.29798153189117e-11
GO:0005085	guanyl-nucleotide exchange factor activity	102/4842	230/18639	0.443478260869565	1.7071440116373	1.05532010016248e-09	3.01553594585205e-07
GO:0003712	transcription coregulator activity	189/4842	495/18639	0.381818181818182	1.46978709023319	1.0602342922624e-09	3.01553594585205e-07
GO:0031267	small GTPase binding	120/4842	283/18639	0.424028268551237	1.63227238693236	1.11192328386875e-09	3.01553594585205e-07
GO:0035091	phosphatidylinositol binding	118/4842	284/18639	0.415492957746479	1.59941619980104	6.40446751037026e-09	1.44740965734368e-06
GO:0051020	GTPase binding	127/4842	315/18639	0.403174603174603	1.55199740367027	1.51490893534745e-08	2.9345950233302e-06
GO:0005096	GTPase activator activity	112/4842	271/18639	0.413284132841328	1.59091345560296	2.18133840762114e-08	3.69736860091783e-06
GO:0005543	phospholipid binding	183/4842	497/18639	0.368209255533199	1.41740031265661	4.48199467096061e-08	6.75287197091398e-06
GO:0019787	ubiquitin-like protein transferase activity	175/4842	479/18639	0.365344467640919	1.4063724767367	1.62045080740892e-07	2.1973312948465e-05
GO:0141003	histone H2AX kinase activity	135/4842	354/18639	0.38135593220339	1.46800768697625	2.71646496515292e-07	3.34866044795215e-05
GO:0016755	aminoacyltransferase activity	179/4842	496/18639	0.360887096774194	1.38921408442259	3.05683698107832e-07	3.4542257886185e-05
GO:0019902	phosphatase binding	81/4842	190/18639	0.426315789473684	1.6410780669145	4.08652905374025e-07	4.26256415143983e-05
GO:0140996	histone H3 kinase activity	135/4842	357/18639	0.378151260504202	1.45567148792603	4.72775978781065e-07	4.57917305162232e-05
GO:0004842	ubiquitin-protein transferase activity	163/4842	449/18639	0.363028953229399	1.39745903743138	6.72455720272099e-07	6.07899971125978e-05
GO:0035173	histone kinase activity	135/4842	360/18639	0.375	1.44354089219331	8.1042895428392e-07	6.86838538755622e-05
GO:0046915	transition metal ion transmembrane transporter activity	27/4842	45/18639	0.6	2.30966542750929	1.48424285012411e-06	0.000118390194398135
GO:0106310	protein serine kinase activity	134/4842	361/18639	0.371191135734072	1.42887888867149	1.68311169089231e-06	0.000126794414047221
GO:0003713	transcription coactivator activity	100/4842	256/18639	0.390625	1.50368842936803	2.69976701517506e-06	0.00019267810908302
GO:0004674	protein serine/threonine kinase activity	155/4842	433/18639	0.35796766743649	1.37797590940701	3.17946941309888e-06	0.000215568026208104
GO:0023023	MHC protein complex binding	23/4842	37/18639	0.621621621621622	2.3928966140862	3.7921470925373e-06	0.000244864355118123
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	16/4842	22/18639	0.727272727272727	2.79959445758702	5.91973302318428e-06	0.00035679946603673
GO:0061659	ubiquitin-like protein ligase activity	135/4842	372/18639	0.362903225806452	1.39697505696127	6.05190834723066e-06	0.00035679946603673
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	93/4842	243/18639	0.382716049382716	1.473243379687	1.56054607203328e-05	0.00070025812061847
GO:1901981	phosphatidylinositol phosphate binding	74/4842	185/18639	0.4	1.53977695167286	1.97624868013399e-05	0.00070025812061847
GO:0004679	AMP-activated protein kinase activity	94/4842	248/18639	0.379032258064516	1.45906283727066	2.20349695758351e-05	0.00070025812061847
GO:0015605	organophosphate ester transmembrane transporter activity	27/4842	50/18639	0.54	2.07869888475836	2.2613016923771e-05	0.00070025812061847
GO:0004676	3-phosphoinositide-dependent protein kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:0004711	ribosomal protein S6 kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:0035175	histone H3S10 kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:0035979	histone H2AXS139 kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:0044022	histone H3S28 kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:0044023	histone H4S1 kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:0044024	histone H2AS1 kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:0044025	histone H2BS14 kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:0072354	histone H3T3 kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:0072371	histone H2AS121 kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:0072518	Rho-dependent protein serine/threonine kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:0140823	histone H2BS36 kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:0140855	histone H3S57 kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:0140995	histone H2A kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:0140997	histone H4 kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:0140998	histone H2B kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:1990244	histone H2AT120 kinase activity	93/4842	245/18639	0.379591836734694	1.46121690311812	2.27222399020743e-05	0.00070025812061847
GO:0004677	DNA-dependent protein kinase activity	93/4842	246/18639	0.378048780487805	1.45527699700789	2.73173669554554e-05	0.000805268469382555
GO:0140857	histone H3T45 kinase activity	93/4842	246/18639	0.378048780487805	1.45527699700789	2.73173669554554e-05	0.000805268469382555
GO:0061630	ubiquitin protein ligase activity	126/4842	353/18639	0.356940509915014	1.37402192571374	2.96717862220708e-05	0.000856062598236766
GO:0035402	histone H3T11 kinase activity	93/4842	247/18639	0.376518218623482	1.4493851873034	3.27624066497691e-05	0.000906649457491568
GO:0035403	histone H3T6 kinase activity	93/4842	247/18639	0.376518218623482	1.4493851873034	3.27624066497691e-05	0.000906649457491568
GO:0044389	ubiquitin-like protein ligase binding	116/4842	322/18639	0.360248447204969	1.38675563970537	3.82098783813899e-05	0.00103625190170329
GO:0140297	DNA-binding transcription factor binding	166/4842	488/18639	0.340163934426229	1.30944146504967	3.9584096265896e-05	0.00105247126542265
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	124/4842	349/18639	0.355300859598854	1.36771018629968	4.33244385699061e-05	0.00112976805193832
GO:0003779	actin binding	152/4842	443/18639	0.343115124153499	1.32080189985483	5.06576597459913e-05	0.00128190309869738
GO:0046332	SMAD binding	37/4842	79/18639	0.468354430379747	1.80290339278152	5.10492384437011e-05	0.00128190309869738
GO:0023026	MHC class II protein complex binding	17/4842	27/18639	0.62962962962963	2.42372297948506	5.66334052142184e-05	0.00139627086309964
GO:0019903	protein phosphatase binding	59/4842	144/18639	0.409722222222222	1.57720208591491	5.87895296422818e-05	0.00142354646776668
GO:0003714	transcription corepressor activity	78/4842	204/18639	0.382352941176471	1.47184561556965	7.53240656168604e-05	0.00179191987678005
GO:1901505	carbohydrate derivative transmembrane transporter activity	27/4842	53/18639	0.509433962264151	1.96103668373431	8.71836217376935e-05	0.00203829294959159
GO:0031625	ubiquitin protein ligase binding	108/4842	302/18639	0.357615894039735	1.37662177798567	9.71866333232882e-05	0.00220845413750152
GO:0001618	virus receptor activity	37/4842	81/18639	0.45679012345679	1.75838725962642	9.8779615732013e-05	0.00220845413750152
GO:0032266	phosphatidylinositol-3-phosphate binding	25/4842	48/18639	0.520833333333333	2.00491790582404	9.93478631176938e-05	0.00220845413750152
GO:0140272	exogenous protein binding	37/4842	82/18639	0.451219512195122	1.7369435125578	0.000135326433662459	0.00295972006526281
GO:0140318	protein transporter activity	22/4842	41/18639	0.536585365853659	2.06555444736603	0.000145523549144	0.00313222115300419
GO:0016409	palmitoyltransferase activity	20/4842	36/18639	0.555555555555556	2.13857909954564	0.000154439098553639	0.00327217840060522
GO:0005338	nucleotide-sugar transmembrane transporter activity	10/4842	13/18639	0.769230769230769	2.96110952244781	0.000177846802519596	0.0037101579110242
GO:0016758	hexosyltransferase activity	74/4842	197/18639	0.375634517766497	1.44598343177401	0.000215578986631884	0.00442916827080054
GO:0016757	glycosyltransferase activity	95/4842	267/18639	0.355805243445693	1.36965178285507	0.000302174955248537	0.00611566028831367
GO:0004197	cysteine-type endopeptidase activity	38/4842	88/18639	0.431818181818182	1.66225920919229	0.000334395402698659	0.00665736615258944
GO:0001221	transcription coregulator binding	47/4842	115/18639	0.408695652173913	1.57325036366575	0.00033875978210079	0.00665736615258944
GO:0019887	protein kinase regulator activity	91/4842	255/18639	0.356862745098039	1.37372257453167	0.00035665598063194	0.00690893585338444
GO:0032934	sterol binding	31/4842	68/18639	0.455882352941176	1.75489284933304	0.000367518712253811	0.0070190897720587
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	28/4842	60/18639	0.466666666666667	1.79640644361834	0.000434844749078202	0.00804308286709244
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	38/4842	89/18639	0.426966292134831	1.64358213942609	0.00043892930100652	0.00804308286709244
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	38/4842	89/18639	0.426966292134831	1.64358213942609	0.00043892930100652	0.00804308286709244
GO:0051019	mitogen-activated protein kinase binding	16/4842	28/18639	0.571428571428571	2.19968135953266	0.000460121983542598	0.00831900546245016
GO:0019207	kinase regulator activity	100/4842	287/18639	0.348432055749129	1.34126912166626	0.000498531452727571	0.00889485065656035
GO:0019209	kinase activator activity	57/4842	148/18639	0.385135135135135	1.48255551090124	0.000529572377355631	0.00932597589213292
GO:0032395	MHC class II receptor activity	8/4842	10/18639	0.8	3.07955390334573	0.000550706775011564	0.00949465282404272
GO:0051010	microtubule plus-end binding	13/4842	21/18639	0.619047619047619	2.38298813949372	0.000553154552433167	0.00949465282404272
GO:0140793	histone H2AXY142 phosphatase activity	38/4842	90/18639	0.422222222222222	1.62532011565469	0.000571508757762102	0.0096043035579199
GO:0030295	protein kinase activator activity	54/4842	139/18639	0.388489208633094	1.49546682356717	0.000573708398371322	0.0096043035579199
GO:0004713	protein tyrosine kinase activity	54/4842	140/18639	0.385714285714286	1.48478491768455	0.000700934322428726	0.0113501876343022
GO:0003756	protein disulfide isomerase activity	12/4842	19/18639	0.631578947368421	2.43122676579926	0.000703108968496598	0.0113501876343022
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	12/4842	19/18639	0.631578947368421	2.43122676579926	0.000703108968496598	0.0113501876343022
GO:0019894	kinesin binding	21/4842	42/18639	0.5	1.92472118959108	0.000719461737067729	0.0114775307701628
GO:0042393	histone binding	87/4842	247/18639	0.352226720647773	1.35587646554189	0.000759998484268059	0.0119832319147382
GO:0042605	peptide antigen binding	22/4842	45/18639	0.488888888888889	1.88194960760017	0.000800808544733235	0.0123397316665712
GO:0140303	intramembrane lipid transporter activity	22/4842	45/18639	0.488888888888889	1.88194960760017	0.000800808544733235	0.0123397316665712
GO:0051787	misfolded protein binding	11/4842	17/18639	0.647058823529412	2.49081565711787	0.000884654462937316	0.0134785556375618
GO:0004725	protein tyrosine phosphatase activity	40/4842	98/18639	0.408163265306122	1.57120097109476	0.000931729429095143	0.0140380567317002
GO:0001540	amyloid-beta binding	35/4842	83/18639	0.421686746987952	1.62325883459489	0.000950892865638123	0.0140680740060095
GO:0022884	macromolecule transmembrane transporter activity	17/4842	32/18639	0.53125	2.04501626394052	0.000954471097752859	0.0140680740060095
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	81/4842	229/18639	0.353711790393013	1.36159315595526	0.000981822328103362	0.0143156029775071
GO:0042277	peptide binding	87/4842	249/18639	0.349397590361446	1.34498589152148	0.0010087435514854	0.0145516622958957
GO:0005385	zinc ion transmembrane transporter activity	15/4842	27/18639	0.555555555555556	2.13857909954564	0.00103267309511275	0.0145865074684676
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	15/4842	27/18639	0.555555555555556	2.13857909954564	0.00103267309511275	0.0145865074684676
GO:0004712	protein serine/threonine/tyrosine kinase activity	21/4842	43/18639	0.488372093023256	1.87996023169361	0.00106485738109333	0.0148860475130161
GO:0051213	dioxygenase activity	38/4842	93/18639	0.408602150537634	1.57289043450454	0.00120486049022526	0.0166713349463822
GO:0001222	transcription corepressor binding	23/4842	49/18639	0.469387755102041	1.80688111675897	0.00124777295321871	0.0170907083289351
GO:0001965	G-protein alpha-subunit binding	16/4842	30/18639	0.533333333333333	2.05303593556382	0.00127068658532172	0.0172305100969625
GO:0035401	histone H3Y41 kinase activity	45/4842	115/18639	0.391304347826087	1.50630353967997	0.00132818422506621	0.0174944516735165
GO:0140801	histone H2AXY142 kinase activity	45/4842	115/18639	0.391304347826087	1.50630353967997	0.00132818422506621	0.0174944516735165
GO:0016922	nuclear receptor binding	52/4842	137/18639	0.37956204379562	1.46110221691585	0.00132885584245738	0.0174944516735165
GO:0008432	JUN kinase binding	8/4842	11/18639	0.727272727272727	2.79959445758702	0.0015570808500359	0.0201085869776065
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	8/4842	11/18639	0.727272727272727	2.79959445758702	0.0015570808500359	0.0201085869776065
GO:0140658	ATP-dependent chromatin remodeler activity	58/4842	158/18639	0.367088607594937	1.41308644299092	0.00183657838726889	0.0234943423880812
GO:0070063	RNA polymerase binding	26/4842	59/18639	0.440677966101695	1.69636443828366	0.00194812156314991	0.0246883442956194
GO:0140327	flippase activity	10/4842	16/18639	0.625	2.40590148698885	0.00224468930605614	0.0281014289939321
GO:0043548	phosphatidylinositol 3-kinase binding	14/4842	26/18639	0.538461538461538	2.07277666571347	0.00225889067871578	0.0281014289939321
GO:0061775	cohesin loader activity	56/4842	153/18639	0.366013071895425	1.40894623028889	0.00234671722256168	0.0289286232163058
GO:0016417	S-acyltransferase activity	15/4842	29/18639	0.517241379310345	1.99109088578387	0.00267189211247624	0.0326404117524125
GO:0005161	platelet-derived growth factor receptor binding	9/4842	14/18639	0.642857142857143	2.47464152947424	0.00286613685418829	0.0347007283417797
GO:0008375	acetylglucosaminyltransferase activity	20/4842	43/18639	0.465116279069767	1.79043831589868	0.00290954094057133	0.0349144912868559
GO:0140033	acetylation-dependent protein binding	13/4842	24/18639	0.541666666666667	2.085114622057	0.00301688151790426	0.0358850117392822
GO:0008194	UDP-glycosyltransferase activity	53/4842	145/18639	0.36551724137931	1.40703755928727	0.0031185681755535	0.036771986487396
GO:0032182	ubiquitin-like protein binding	45/4842	120/18639	0.375	1.44354089219331	0.00352979798428313	0.0404158691949525
GO:0005025	transforming growth factor beta receptor activity, type I	8/4842	12/18639	0.666666666666667	2.56629491945477	0.00360643080574428	0.0404158691949525
GO:0005026	transforming growth factor beta receptor activity, type II	8/4842	12/18639	0.666666666666667	2.56629491945477	0.00360643080574428	0.0404158691949525
GO:0016361	activin receptor activity, type I	8/4842	12/18639	0.666666666666667	2.56629491945477	0.00360643080574428	0.0404158691949525
GO:0016362	activin receptor activity, type II	8/4842	12/18639	0.666666666666667	2.56629491945477	0.00360643080574428	0.0404158691949525
GO:0017002	activin receptor activity	8/4842	12/18639	0.666666666666667	2.56629491945477	0.00360643080574428	0.0404158691949525
GO:1990782	protein tyrosine kinase binding	44/4842	117/18639	0.376068376068376	1.44765354430782	0.00365436716825863	0.0406173924603172
GO:0016798	hydrolase activity, acting on glycosyl bonds	48/4842	130/18639	0.369230769230769	1.42133257077495	0.00378165063204917	0.0416903923338103
GO:0051015	actin filament binding	72/4842	209/18639	0.344497607655502	1.32612369043596	0.00388631441388661	0.0424987285905665
GO:0032452	histone demethylase activity	15/4842	30/18639	0.5	1.92472118959108	0.00407309763963077	0.0441849631947146
GO:0008484	sulfuric ester hydrolase activity	10/4842	17/18639	0.588235294117647	2.26437787010715	0.00418759622479729	0.0447116573293317
GO:0070403	NAD+ binding	10/4842	17/18639	0.588235294117647	2.26437787010715	0.00418759622479729	0.0447116573293317
GO:0070513	death domain binding	7/4842	10/18639	0.7	2.69460966542751	0.00442821300947452	0.0469113815691207
GO:0000030	mannosyltransferase activity	13/4842	25/18639	0.52	2.00171003717472	0.00480385324757416	0.0487552768913273
GO:0019706	protein-cysteine S-palmitoyltransferase activity	13/4842	25/18639	0.52	2.00171003717472	0.00480385324757416	0.0487552768913273
GO:0019707	protein-cysteine S-acyltransferase activity	13/4842	25/18639	0.52	2.00171003717472	0.00480385324757416	0.0487552768913273
GO:0000510	H3-H4 histone complex chaperone activity	54/4842	151/18639	0.357615894039735	1.37662177798567	0.00485395455776489	0.0487552768913273
GO:0140584	chromatin extrusion motor activity	54/4842	151/18639	0.357615894039735	1.37662177798567	0.00485395455776489	0.0487552768913273
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	54/4842	151/18639	0.357615894039735	1.37662177798567	0.00485395455776489	0.0487552768913273
GO:0140849	ATP-dependent H2AZ histone chaperone activity	54/4842	151/18639	0.357615894039735	1.37662177798567	0.00485395455776489	0.0487552768913273
GO:0030742	GTP-dependent protein binding	11/4842	20/18639	0.55	2.11719330855019	0.00540234416919795	0.0529378176115708
GO:0052745	inositol phosphate phosphatase activity	11/4842	20/18639	0.55	2.11719330855019	0.00540234416919795	0.0529378176115708
GO:0019789	SUMO transferase activity	14/4842	28/18639	0.5	1.92472118959108	0.00546555639057516	0.0529378176115708
GO:0046966	nuclear thyroid hormone receptor binding	14/4842	28/18639	0.5	1.92472118959108	0.00546555639057516	0.0529378176115708
GO:0141052	histone H3 demethylase activity	14/4842	28/18639	0.5	1.92472118959108	0.00546555639057516	0.0529378176115708
GO:0015616	DNA translocase activity	54/4842	152/18639	0.355263157894737	1.36756505576208	0.00565915888762811	0.0540409820536881
GO:0140674	ATP-dependent histone chaperone activity	54/4842	152/18639	0.355263157894737	1.36756505576208	0.00565915888762811	0.0540409820536881
GO:0015485	cholesterol binding	23/4842	54/18639	0.425925925925926	1.63957730965166	0.00578621796228047	0.0546228478824254
GO:0015932	nucleobase-containing compound transmembrane transporter activity	24/4842	57/18639	0.421052631578947	1.62081784386617	0.00580065641229296	0.0546228478824254
GO:0019838	growth factor binding	49/4842	136/18639	0.360294117647059	1.38693144544063	0.00599300962590984	0.0559012979685269
GO:0140457	protein demethylase activity	15/4842	31/18639	0.483870967741935	1.86263340928169	0.00601887131519538	0.0559012979685269
GO:0019888	protein phosphatase regulator activity	40/4842	107/18639	0.373831775700935	1.4390438800681	0.00607665577767453	0.0560540492144671
GO:0005158	insulin receptor binding	12/4842	23/18639	0.521739130434783	2.0084047195733	0.006460409338588	0.0585615560213867
GO:0070577	lysine-acetylated histone binding	12/4842	23/18639	0.521739130434783	2.0084047195733	0.006460409338588	0.0585615560213867
GO:0019208	phosphatase regulator activity	43/4842	117/18639	0.367521367521368	1.41475232739173	0.00647804823245428	0.0585615560213867
GO:0140034	methylation-dependent protein binding	30/4842	76/18639	0.394736842105263	1.51951672862454	0.00679028892887689	0.0609776939573315
GO:0043539	protein serine/threonine kinase activator activity	29/4842	73/18639	0.397260273972603	1.52923053419565	0.00694457846157349	0.0616967537593033
GO:0003689	DNA clamp loader activity	56/4842	160/18639	0.35	1.34730483271375	0.00696135938434617	0.0616967537593033
GO:0032451	demethylase activity	18/4842	40/18639	0.45	1.73224907063197	0.00710005713621517	0.0625173862123881
GO:0035673	oligopeptide transmembrane transporter activity	8/4842	13/18639	0.615384615384615	2.36888761795825	0.00724845804866079	0.0630058276537438
GO:0070123	transforming growth factor beta receptor activity, type III	8/4842	13/18639	0.615384615384615	2.36888761795825	0.00724845804866079	0.0630058276537438
GO:0008234	cysteine-type peptidase activity	64/4842	187/18639	0.342245989304813	1.31745621533507	0.00729679655500625	0.0630220135578884
GO:0030165	PDZ domain binding	32/4842	83/18639	0.385542168674699	1.48412236305818	0.00794084526317829	0.0681505454232263
GO:0005178	integrin binding	56/4842	161/18639	0.347826086956522	1.33893647971553	0.00802437725633385	0.0684343116955265
GO:0140597	protein carrier chaperone	64/4842	188/18639	0.340425531914894	1.31044846950882	0.00830934896780437	0.070421732502142
GO:0140097	catalytic activity, acting on DNA	107/4842	336/18639	0.318452380952381	1.22586409098956	0.0088723197773101	0.0747258734039285
GO:0035591	signaling adaptor activity	46/4842	129/18639	0.356589147286822	1.37266937552232	0.00933824381134416	0.0781645593097696
GO:0042608	T cell receptor binding	7/4842	11/18639	0.636363636363636	2.44964515038864	0.00945269428849209	0.0786371377619342
GO:0034450	ubiquitin-ubiquitin ligase activity	9/4842	16/18639	0.5625	2.16531133828996	0.00973129297825075	0.0802992116571672
GO:0001223	transcription coactivator binding	19/4842	44/18639	0.431818181818182	1.66225920919229	0.00977092177244291	0.0802992116571672
GO:0035035	histone acetyltransferase binding	12/4842	24/18639	0.5	1.92472118959108	0.00990393715927175	0.0809020408914006
GO:0140030	modification-dependent protein binding	59/4842	173/18639	0.341040462427746	1.31281560908524	0.0104857317107074	0.0851416299384389
GO:0008320	protein transmembrane transporter activity	13/4842	27/18639	0.481481481481481	1.85343521960622	0.0108489572892808	0.087566583834909
GO:0008017	microtubule binding	89/4842	276/18639	0.322463768115942	1.24130569473627	0.0112458047774782	0.0902326111139672
GO:0005520	insulin-like growth factor binding	10/4842	19/18639	0.526315789473684	2.02602230483271	0.0117729955396363	0.0933776945246578
GO:0016791	phosphatase activity	88/4842	273/18639	0.322344322344322	1.24084589512099	0.0117755057254546	0.0933776945246578
GO:0015631	tubulin binding	120/4842	385/18639	0.311688311688312	1.19982619610872	0.0120942880449789	0.0953479917964616
GO:0016887	ATP hydrolysis activity	129/4842	417/18639	0.309352517985612	1.19083469284052	0.0123604266582049	0.0968828817833867
GO:0140463	chromatin-protein adaptor activity	22/4842	54/18639	0.407407407407407	1.5682913396668	0.0125503717721523	0.0978063455347039
GO:0032454	histone H3K9 demethylase activity	8/4842	14/18639	0.571428571428571	2.19968135953266	0.0130915529746241	0.0997311563684848
GO:0046030	inositol trisphosphate phosphatase activity	8/4842	14/18639	0.571428571428571	2.19968135953266	0.0130915529746241	0.0997311563684848
GO:0071933	Arp2/3 complex binding	8/4842	14/18639	0.571428571428571	2.19968135953266	0.0130915529746241	0.0997311563684848
GO:0098821	BMP receptor activity	8/4842	14/18639	0.571428571428571	2.19968135953266	0.0130915529746241	0.0997311563684848
GO:0050321	tau-protein kinase activity	11/4842	22/18639	0.5	1.92472118959108	0.0133836007465978	0.10082312562437
GO:0140035	ubiquitin-like protein reader activity	11/4842	22/18639	0.5	1.92472118959108	0.0133836007465978	0.10082312562437
GO:0008238	exopeptidase activity	37/4842	102/18639	0.362745098039216	1.39636635323274	0.0137505696696242	0.103015317524919
GO:0033218	amide binding	80/4842	247/18639	0.323886639676113	1.24678295682013	0.0139068705681607	0.103613826870472
GO:0042974	nuclear retinoic acid receptor binding	12/4842	25/18639	0.48	1.84773234200743	0.0146117069239157	0.108270352944425
GO:0005516	calmodulin binding	68/4842	207/18639	0.328502415458937	1.26455111973134	0.0159070299342216	0.1151730993399
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	9/4842	17/18639	0.529411764705882	2.03794008309644	0.0159679518258859	0.1151730993399
GO:0008429	phosphatidylethanolamine binding	9/4842	17/18639	0.529411764705882	2.03794008309644	0.0159679518258859	0.1151730993399
GO:0019198	transmembrane receptor protein phosphatase activity	9/4842	17/18639	0.529411764705882	2.03794008309644	0.0159679518258859	0.1151730993399
GO:0046965	nuclear retinoid X receptor binding	9/4842	17/18639	0.529411764705882	2.03794008309644	0.0159679518258859	0.1151730993399
GO:0140789	histone phosphatase activity	47/4842	136/18639	0.345588235294118	1.33032199868795	0.0160680342462095	0.115236818026068
GO:0016411	acylglycerol O-acyltransferase activity	14/4842	31/18639	0.451612903225806	1.73845784866291	0.0161467517883134	0.115236818026068
GO:0035064	methylated histone binding	28/4842	74/18639	0.378378378378378	1.45654576509595	0.0164133802226933	0.116526406188336
GO:0008376	acetylgalactosaminyltransferase activity	15/4842	34/18639	0.441176470588235	1.69828340258036	0.0165563333130463	0.116929104023389
GO:0043394	proteoglycan binding	16/4842	37/18639	0.432432432432432	1.66462373153823	0.0167842244702055	0.117924395759578
GO:0043130	ubiquitin binding	36/4842	100/18639	0.36	1.38579925650558	0.0169275514473004	0.11831834929144
GO:0005078	MAP-kinase scaffold activity	7/4842	12/18639	0.583333333333333	2.24550805452292	0.0176374631643391	0.120182914828361
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	7/4842	12/18639	0.583333333333333	2.24550805452292	0.0176374631643391	0.120182914828361
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	7/4842	12/18639	0.583333333333333	2.24550805452292	0.0176374631643391	0.120182914828361
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	7/4842	12/18639	0.583333333333333	2.24550805452292	0.0176374631643391	0.120182914828361
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	7/4842	12/18639	0.583333333333333	2.24550805452292	0.0176374631643391	0.120182914828361
GO:0038024	cargo receptor activity	25/4842	65/18639	0.384615384615385	1.48055476122391	0.0181804485063187	0.123263440872841
GO:0001217	DNA-binding transcription repressor activity	88/4842	278/18639	0.316546762589928	1.21852852290658	0.0190755938971145	0.128689081216355
GO:0051087	protein-folding chaperone binding	46/4842	134/18639	0.343283582089552	1.32145036897298	0.0193281443775444	0.129747345425496
GO:0005319	lipid transporter activity	59/4842	178/18639	0.331460674157303	1.27593876613341	0.0194336335904739	0.129812843096959
GO:0042171	lysophosphatidic acid acyltransferase activity	11/4842	23/18639	0.478260869565217	1.84103765960886	0.0197298595372733	0.130505802597769
GO:0071617	lysophospholipid acyltransferase activity	11/4842	23/18639	0.478260869565217	1.84103765960886	0.0197298595372733	0.130505802597769
GO:0042578	phosphoric ester hydrolase activity	112/4842	363/18639	0.308539944903581	1.18770673958237	0.0201212503427742	0.132448618761174
GO:0042626	ATPase-coupled transmembrane transporter activity	35/4842	98/18639	0.357142857142857	1.37480084970791	0.0207885687577055	0.135191527117082
GO:0008157	protein phosphatase 1 binding	12/4842	26/18639	0.461538461538462	1.77666571346869	0.0208370421589013	0.135191527117082
GO:0050750	low-density lipoprotein particle receptor binding	12/4842	26/18639	0.461538461538462	1.77666571346869	0.0208370421589013	0.135191527117082
GO:0120015	sterol transfer activity	14/4842	32/18639	0.4375	1.68413104089219	0.0219801767813686	0.141066274392992
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	17/4842	41/18639	0.414634146341463	1.59611025478285	0.0219868867591064	0.141066274392992
GO:0015297	antiporter activity	46/4842	135/18639	0.340740740740741	1.31166184772133	0.0221047750444975	0.141066274392992
GO:0010485	histone H4 acetyltransferase activity	15/4842	35/18639	0.428571428571429	1.6497610196495	0.0221586404466868	0.141066274392992
GO:0043178	alcohol binding	33/4842	92/18639	0.358695652173913	1.38077824470664	0.0227390025339378	0.144084520729064
GO:0005381	iron ion transmembrane transporter activity	6/4842	10/18639	0.6	2.30966542750929	0.0237832712697761	0.147936311200993
GO:0016175	superoxide-generating NAD(P)H oxidase activity	6/4842	10/18639	0.6	2.30966542750929	0.0237832712697761	0.147936311200993
GO:0043422	protein kinase B binding	6/4842	10/18639	0.6	2.30966542750929	0.0237832712697761	0.147936311200993
GO:0140999	histone H3K4 trimethyltransferase activity	6/4842	10/18639	0.6	2.30966542750929	0.0237832712697761	0.147936311200993
GO:0140375	immune receptor activity	52/4842	156/18639	0.333333333333333	1.28314745972739	0.0241680903297439	0.149643518206085
GO:0034185	apolipoprotein binding	9/4842	18/18639	0.5	1.92472118959108	0.0246909312794038	0.151497297804849
GO:0070064	proline-rich region binding	9/4842	18/18639	0.5	1.92472118959108	0.0246909312794038	0.151497297804849
GO:0002020	protease binding	46/4842	136/18639	0.338235294117647	1.30201727531161	0.0251902203414002	0.153864589112336
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	10/4842	21/18639	0.476190476190476	1.83306779961055	0.0267206303868002	0.162480604504489
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	84/4842	268/18639	0.313432835820896	1.2065416412362	0.0274105286029552	0.165931592792889
GO:0140713	histone chaperone activity	54/4842	164/18639	0.329268292682927	1.26749931997461	0.02775279547141	0.167256847374364
GO:0043175	RNA polymerase core enzyme binding	17/4842	42/18639	0.404761904761905	1.55810762966897	0.0282079919160109	0.169247951496065
GO:0001968	fibronectin binding	13/4842	30/18639	0.433333333333333	1.6680916976456	0.0291987474654649	0.17098222942308
GO:0015215	nucleotide transmembrane transporter activity	13/4842	30/18639	0.433333333333333	1.6680916976456	0.0291987474654649	0.17098222942308
GO:0043995	histone H4K5 acetyltransferase activity	13/4842	30/18639	0.433333333333333	1.6680916976456	0.0291987474654649	0.17098222942308
GO:0043996	histone H4K8 acetyltransferase activity	13/4842	30/18639	0.433333333333333	1.6680916976456	0.0291987474654649	0.17098222942308
GO:0043997	histone H4K12 acetyltransferase activity	13/4842	30/18639	0.433333333333333	1.6680916976456	0.0291987474654649	0.17098222942308
GO:0005035	death receptor activity	7/4842	13/18639	0.538461538461538	2.07277666571347	0.0297579691326304	0.17098222942308
GO:0031994	insulin-like growth factor I binding	7/4842	13/18639	0.538461538461538	2.07277666571347	0.0297579691326304	0.17098222942308
GO:0035325	Toll-like receptor binding	7/4842	13/18639	0.538461538461538	2.07277666571347	0.0297579691326304	0.17098222942308
GO:0140333	glycerophospholipid flippase activity	7/4842	13/18639	0.538461538461538	2.07277666571347	0.0297579691326304	0.17098222942308
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	7/4842	13/18639	0.538461538461538	2.07277666571347	0.0297579691326304	0.17098222942308
GO:0004721	phosphoprotein phosphatase activity	57/4842	175/18639	0.325714285714286	1.25381837493362	0.0300208846736357	0.171765061677004
GO:0008094	ATP-dependent activity, acting on DNA	67/4842	210/18639	0.319047619047619	1.22815542573907	0.0312619291449861	0.177672091183249
GO:0008374	O-acyltransferase activity	21/4842	55/18639	0.381818181818182	1.46978709023319	0.0313153612041272	0.177672091183249
GO:0030971	receptor tyrosine kinase binding	29/4842	81/18639	0.358024691358025	1.37819541970719	0.0320748443021548	0.180324556336939
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	144/4842	484/18639	0.297520661157025	1.14528864174015	0.0323093141215201	0.180324556336939
GO:0005548	phospholipid transporter activity	25/4842	68/18639	0.367647058823529	1.41523616881697	0.032314798812593	0.180324556336939
GO:0030145	manganese ion binding	25/4842	68/18639	0.367647058823529	1.41523616881697	0.032314798812593	0.180324556336939
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	32/4842	91/18639	0.351648351648352	1.35365006740471	0.0326265814784628	0.181318215101621
GO:0004708	MAP kinase kinase activity	8/4842	16/18639	0.5	1.92472118959108	0.033758040541244	0.183103611895708
GO:0005024	transforming growth factor beta receptor activity	8/4842	16/18639	0.5	1.92472118959108	0.033758040541244	0.183103611895708
GO:0008142	oxysterol binding	8/4842	16/18639	0.5	1.92472118959108	0.033758040541244	0.183103611895708
GO:0015923	mannosidase activity	8/4842	16/18639	0.5	1.92472118959108	0.033758040541244	0.183103611895708
GO:0016722	oxidoreductase activity, acting on metal ions	8/4842	16/18639	0.5	1.92472118959108	0.033758040541244	0.183103611895708
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	8/4842	16/18639	0.5	1.92472118959108	0.033758040541244	0.183103611895708
GO:0005496	steroid binding	37/4842	108/18639	0.342592592592593	1.31879044471981	0.0342026456479271	0.184776045811112
GO:0016853	isomerase activity	58/4842	180/18639	0.322222222222222	1.24037587773647	0.0354090367563287	0.190534340641197
GO:0042800	histone H3K4 methyltransferase activity	9/4842	19/18639	0.473684210526316	1.82342007434944	0.0363170734451945	0.193121378790917
GO:0043395	heparan sulfate proteoglycan binding	9/4842	19/18639	0.473684210526316	1.82342007434944	0.0363170734451945	0.193121378790917
GO:0140036	ubiquitin-modified protein reader activity	9/4842	19/18639	0.473684210526316	1.82342007434944	0.0363170734451945	0.193121378790917
GO:0052866	phosphatidylinositol phosphate phosphatase activity	14/4842	34/18639	0.411764705882353	1.58506450907501	0.0381451742868207	0.202050220050503
GO:0004709	MAP kinase kinase kinase activity	11/4842	25/18639	0.44	1.69375464684015	0.0385981258980457	0.20286456867345
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	11/4842	25/18639	0.44	1.69375464684015	0.0385981258980457	0.20286456867345
GO:0036408	histone H3K14 acetyltransferase activity	12/4842	28/18639	0.428571428571429	1.6497610196495	0.0388122140444268	0.203202170827192
GO:0001216	DNA-binding transcription activator activity	145/4842	491/18639	0.295315682281059	1.1368007026098	0.039867654167014	0.207925150194119
GO:0002162	dystroglycan binding	6/4842	11/18639	0.545454545454545	2.09969584319027	0.0409799636473169	0.209693700776459
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	6/4842	11/18639	0.545454545454545	2.09969584319027	0.0409799636473169	0.209693700776459
GO:0032794	GTPase activating protein binding	6/4842	11/18639	0.545454545454545	2.09969584319027	0.0409799636473169	0.209693700776459
GO:0047676	arachidonate-CoA ligase activity	6/4842	11/18639	0.545454545454545	2.09969584319027	0.0409799636473169	0.209693700776459
GO:0140537	transcription regulator activator activity	6/4842	11/18639	0.545454545454545	2.09969584319027	0.0409799636473169	0.209693700776459
GO:0061733	protein-lysine-acetyltransferase activity	18/4842	47/18639	0.382978723404255	1.47425452819742	0.04286139469771	0.21767809441983
GO:0140938	histone H3 methyltransferase activity	18/4842	47/18639	0.382978723404255	1.47425452819742	0.04286139469771	0.21767809441983
GO:0140104	molecular carrier activity	77/4842	249/18639	0.309236947791165	1.19038981203625	0.0446434375390751	0.225882467548455
GO:0016877	ligase activity, forming carbon-sulfur bonds	16/4842	41/18639	0.390243902439024	1.50222141626621	0.0459612161640193	0.230591452212833
GO:0004065	arylsulfatase activity	7/4842	14/18639	0.5	1.92472118959108	0.0464243852906367	0.230591452212833
GO:0005545	1-phosphatidylinositol binding	7/4842	14/18639	0.5	1.92472118959108	0.0464243852906367	0.230591452212833
GO:0008191	metalloendopeptidase inhibitor activity	7/4842	14/18639	0.5	1.92472118959108	0.0464243852906367	0.230591452212833
GO:0061665	SUMO ligase activity	7/4842	14/18639	0.5	1.92472118959108	0.0464243852906367	0.230591452212833
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	20/4842	54/18639	0.37037037037037	1.42571939969709	0.0481254373105015	0.237302156338327
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	20/4842	54/18639	0.37037037037037	1.42571939969709	0.0481254373105015	0.237302156338327
GO:0015278	intracellularly gated calcium channel activity	8/4842	17/18639	0.470588235294118	1.81150229608572	0.0495714527326734	0.24119892295188
GO:0016805	dipeptidase activity	8/4842	17/18639	0.470588235294118	1.81150229608572	0.0495714527326734	0.24119892295188
GO:0031490	chromatin DNA binding	42/4842	128/18639	0.328125	1.26309828066915	0.050108611083351	0.24119892295188
GO:0051117	ATPase binding	29/4842	84/18639	0.345238095238095	1.32897415471765	0.0508899789638132	0.24119892295188
GO:0010484	histone H3 acetyltransferase activity	12/4842	29/18639	0.413793103448276	1.5928727086271	0.0509896352379251	0.24119892295188
GO:0051861	glycolipid binding	12/4842	29/18639	0.413793103448276	1.5928727086271	0.0509896352379251	0.24119892295188
GO:0015095	magnesium ion transmembrane transporter activity	9/4842	20/18639	0.45	1.73224907063197	0.0511862406102926	0.24119892295188
GO:0042288	MHC class I protein binding	9/4842	20/18639	0.45	1.73224907063197	0.0511862406102926	0.24119892295188
GO:0005112	Notch binding	11/4842	26/18639	0.423076923076923	1.6286102373463	0.051622920640085	0.24119892295188
GO:0015216	purine nucleotide transmembrane transporter activity	11/4842	26/18639	0.423076923076923	1.6286102373463	0.051622920640085	0.24119892295188
GO:0050681	nuclear androgen receptor binding	11/4842	26/18639	0.423076923076923	1.6286102373463	0.051622920640085	0.24119892295188
GO:0070006	metalloaminopeptidase activity	11/4842	26/18639	0.423076923076923	1.6286102373463	0.051622920640085	0.24119892295188
GO:0070412	R-SMAD binding	11/4842	26/18639	0.423076923076923	1.6286102373463	0.051622920640085	0.24119892295188
GO:0004602	glutathione peroxidase activity	10/4842	23/18639	0.434782608695652	1.67367059964442	0.0517617157662221	0.24119892295188
GO:0140103	catalytic activity, acting on a glycoprotein	10/4842	23/18639	0.434782608695652	1.67367059964442	0.0517617157662221	0.24119892295188
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	10/4842	23/18639	0.434782608695652	1.67367059964442	0.0517617157662221	0.24119892295188
GO:0019905	syntaxin binding	22/4842	61/18639	0.360655737704918	1.38832348101652	0.0525284727569003	0.243933592665605
GO:0015291	secondary active transmembrane transporter activity	87/4842	287/18639	0.303135888501742	1.16690413584964	0.0542710023473109	0.251165457962299
GO:0017124	SH3 domain binding	38/4842	115/18639	0.330434782608696	1.27198965572976	0.054483251766316	0.251290099983417
GO:0004518	nuclease activity	65/4842	209/18639	0.311004784688995	1.19719499831024	0.054671359874808	0.251302928780474
GO:0019199	transmembrane receptor protein kinase activity	27/4842	78/18639	0.346153846153846	1.33249928510152	0.0563045532376134	0.257935723615553
GO:0004402	histone acetyltransferase activity	16/4842	42/18639	0.380952380952381	1.46645423968844	0.0568862772397168	0.25885165079549
GO:0048487	beta-tubulin binding	16/4842	42/18639	0.380952380952381	1.46645423968844	0.0568862772397168	0.25885165079549
GO:0140313	molecular sequestering activity	20/4842	55/18639	0.363636363636364	1.39979722879351	0.0577311950855727	0.261817727545273
GO:0120013	lipid transfer activity	23/4842	65/18639	0.353846153846154	1.36211038032599	0.059062079314743	0.266960598502638
GO:0000993	RNA polymerase II complex binding	14/4842	36/18639	0.388888888888889	1.49700536968195	0.0613581093003391	0.276417263160331
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	13/4842	33/18639	0.393939393939394	1.51644699785964	0.0635067305056189	0.283185913508701
GO:0030296	protein tyrosine kinase activator activity	13/4842	33/18639	0.393939393939394	1.51644699785964	0.0635067305056189	0.283185913508701
GO:0019955	cytokine binding	46/4842	144/18639	0.319444444444444	1.22968298223874	0.0635530178825466	0.283185913508701
GO:0005095	GTPase inhibitor activity	6/4842	12/18639	0.5	1.92472118959108	0.0643224641302948	0.283185913508701
GO:0016208	AMP binding	6/4842	12/18639	0.5	1.92472118959108	0.0643224641302948	0.283185913508701
GO:0045295	gamma-catenin binding	6/4842	12/18639	0.5	1.92472118959108	0.0643224641302948	0.283185913508701
GO:0070008	serine-type exopeptidase activity	6/4842	12/18639	0.5	1.92472118959108	0.0643224641302948	0.283185913508701
GO:0031624	ubiquitin conjugating enzyme binding	12/4842	30/18639	0.4	1.53977695167286	0.0655168937528988	0.287511028896216
GO:0004180	carboxypeptidase activity	17/4842	46/18639	0.369565217391304	1.42262000969775	0.0663769387082309	0.28941198999473
GO:0030276	clathrin binding	17/4842	46/18639	0.369565217391304	1.42262000969775	0.0663769387082309	0.28941198999473
GO:0016405	CoA-ligase activity	11/4842	27/18639	0.407407407407407	1.5682913396668	0.0672947654176074	0.290137196047511
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	11/4842	27/18639	0.407407407407407	1.5682913396668	0.0672947654176074	0.290137196047511
GO:0004559	alpha-mannosidase activity	7/4842	15/18639	0.466666666666667	1.79640644361834	0.0680191390051648	0.290137196047511
GO:0047372	monoacylglycerol lipase activity	7/4842	15/18639	0.466666666666667	1.79640644361834	0.0680191390051648	0.290137196047511
GO:0120283	protein serine/threonine kinase binding	7/4842	15/18639	0.466666666666667	1.79640644361834	0.0680191390051648	0.290137196047511
GO:0004622	lysophospholipase activity	10/4842	24/18639	0.416666666666667	1.60393432465923	0.0687028687782176	0.290137196047511
GO:0000900	mRNA regulatory element binding translation repressor activity	8/4842	18/18639	0.444444444444444	1.71086327963651	0.069475869895289	0.290137196047511
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	8/4842	18/18639	0.444444444444444	1.71086327963651	0.069475869895289	0.290137196047511
GO:0004706	JUN kinase kinase kinase activity	8/4842	18/18639	0.444444444444444	1.71086327963651	0.069475869895289	0.290137196047511
GO:0016854	racemase and epimerase activity	8/4842	18/18639	0.444444444444444	1.71086327963651	0.069475869895289	0.290137196047511
GO:0030228	lipoprotein particle receptor activity	8/4842	18/18639	0.444444444444444	1.71086327963651	0.069475869895289	0.290137196047511
GO:0035615	clathrin adaptor activity	8/4842	18/18639	0.444444444444444	1.71086327963651	0.069475869895289	0.290137196047511
GO:0140312	cargo adaptor activity	9/4842	21/18639	0.428571428571429	1.6497610196495	0.0695354482779117	0.290137196047511
GO:0022804	active transmembrane transporter activity	133/4842	457/18639	0.291028446389497	1.12029723507927	0.0695387822385259	0.290137196047511
GO:0031072	heat shock protein binding	42/4842	131/18639	0.320610687022901	1.23417236584466	0.0698936113500613	0.290723119603322
GO:0034212	protein N-acetyltransferase activity	19/4842	53/18639	0.358490566037736	1.37998877744266	0.0721165957593669	0.298140560517383
GO:0051018	protein kinase A binding	19/4842	53/18639	0.358490566037736	1.37998877744266	0.0721165957593669	0.298140560517383
GO:0008175	tRNA methyltransferase activity	13/4842	34/18639	0.382352941176471	1.47184561556965	0.0792067414982085	0.325467701429002
GO:0030332	cyclin binding	13/4842	34/18639	0.382352941176471	1.47184561556965	0.0792067414982085	0.325467701429002
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	23/4842	67/18639	0.343283582089552	1.32145036897298	0.0802525503961164	0.327778488967271
GO:0050840	extracellular matrix binding	23/4842	67/18639	0.343283582089552	1.32145036897298	0.0802525503961164	0.327778488967271
GO:0004860	protein kinase inhibitor activity	28/4842	84/18639	0.333333333333333	1.28314745972739	0.0808366207291134	0.329172545671705
GO:0070325	lipoprotein particle receptor binding	12/4842	31/18639	0.387096774193548	1.49010672742535	0.0825011284676649	0.334944701204053
GO:0043014	alpha-tubulin binding	16/4842	44/18639	0.363636363636364	1.39979722879351	0.0837812280667119	0.339126403756601
GO:0051287	NAD binding	19/4842	54/18639	0.351851851851852	1.35443342971224	0.0851403674887509	0.339996504156565
GO:0051959	dynein light intermediate chain binding	11/4842	28/18639	0.392857142857143	1.5122809346787	0.0857246516002536	0.339996504156565
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	11/4842	28/18639	0.392857142857143	1.5122809346787	0.0857246516002536	0.339996504156565
GO:0042169	SH2 domain binding	15/4842	41/18639	0.365853658536585	1.40833257774957	0.0880545009963837	0.339996504156565
GO:0015296	monoatomic anion:monoatomic cation symporter activity	10/4842	25/18639	0.4	1.53977695167286	0.0887726973649988	0.339996504156565
GO:0015645	fatty acid ligase activity	10/4842	25/18639	0.4	1.53977695167286	0.0887726973649988	0.339996504156565
GO:0015662	P-type ion transporter activity	10/4842	25/18639	0.4	1.53977695167286	0.0887726973649988	0.339996504156565
GO:0120020	cholesterol transfer activity	10/4842	25/18639	0.4	1.53977695167286	0.0887726973649988	0.339996504156565
GO:0120515	fatty acid-CoA ligase activity	10/4842	25/18639	0.4	1.53977695167286	0.0887726973649988	0.339996504156565
GO:0140358	P-type transmembrane transporter activity	10/4842	25/18639	0.4	1.53977695167286	0.0887726973649988	0.339996504156565
GO:0045296	cadherin binding	98/4842	334/18639	0.293413173652695	1.12947710526902	0.0894369732741708	0.339996504156565
GO:0005048	signal sequence binding	18/4842	51/18639	0.352941176470588	1.35862672206429	0.0897624007337164	0.339996504156565
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	5/4842	10/18639	0.5	1.92472118959108	0.0900138237405654	0.339996504156565
GO:0005031	tumor necrosis factor receptor activity	5/4842	10/18639	0.5	1.92472118959108	0.0900138237405654	0.339996504156565
GO:0005522	profilin binding	5/4842	10/18639	0.5	1.92472118959108	0.0900138237405654	0.339996504156565
GO:0008641	ubiquitin-like modifier activating enzyme activity	5/4842	10/18639	0.5	1.92472118959108	0.0900138237405654	0.339996504156565
GO:0015279	store-operated calcium channel activity	5/4842	10/18639	0.5	1.92472118959108	0.0900138237405654	0.339996504156565
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	5/4842	10/18639	0.5	1.92472118959108	0.0900138237405654	0.339996504156565
GO:0019911	structural constituent of myelin sheath	5/4842	10/18639	0.5	1.92472118959108	0.0900138237405654	0.339996504156565
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	5/4842	10/18639	0.5	1.92472118959108	0.0900138237405654	0.339996504156565
GO:0045322	unmethylated CpG binding	5/4842	10/18639	0.5	1.92472118959108	0.0900138237405654	0.339996504156565
GO:0051864	histone H3K36 demethylase activity	5/4842	10/18639	0.5	1.92472118959108	0.0900138237405654	0.339996504156565
GO:0099122	RNA polymerase II C-terminal domain binding	5/4842	10/18639	0.5	1.92472118959108	0.0900138237405654	0.339996504156565
GO:1905394	retromer complex binding	5/4842	10/18639	0.5	1.92472118959108	0.0900138237405654	0.339996504156565
GO:0030246	carbohydrate binding	83/4842	280/18639	0.296428571428571	1.14108470525757	0.0912957985643508	0.340754065046083
GO:0015377	chloride:monoatomic cation symporter activity	9/4842	22/18639	0.409090909090909	1.5747718823927	0.0914820358716412	0.340754065046083
GO:0042887	amide transmembrane transporter activity	14/4842	38/18639	0.368421052631579	1.4182156133829	0.0925207736797696	0.340754065046083
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	8/4842	19/18639	0.421052631578947	1.62081784386617	0.0935913582226305	0.340754065046083
GO:0005346	purine ribonucleotide transmembrane transporter activity	8/4842	19/18639	0.421052631578947	1.62081784386617	0.0935913582226305	0.340754065046083
GO:0046527	glucosyltransferase activity	8/4842	19/18639	0.421052631578947	1.62081784386617	0.0935913582226305	0.340754065046083
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	6/4842	13/18639	0.461538461538462	1.77666571346869	0.093949174128293	0.340754065046083
GO:0017154	semaphorin receptor activity	6/4842	13/18639	0.461538461538462	1.77666571346869	0.093949174128293	0.340754065046083
GO:0046974	histone H3K9 methyltransferase activity	6/4842	13/18639	0.461538461538462	1.77666571346869	0.093949174128293	0.340754065046083
GO:0046975	histone H3K36 methyltransferase activity	6/4842	13/18639	0.461538461538462	1.77666571346869	0.093949174128293	0.340754065046083
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	6/4842	13/18639	0.461538461538462	1.77666571346869	0.093949174128293	0.340754065046083
GO:0097157	pre-mRNA intronic binding	6/4842	13/18639	0.461538461538462	1.77666571346869	0.093949174128293	0.340754065046083
GO:0000149	SNARE binding	34/4842	106/18639	0.320754716981132	1.23472680086975	0.0945284440595597	0.340754065046083
GO:0015562	efflux transmembrane transporter activity	7/4842	16/18639	0.4375	1.68413104089219	0.0946666600326586	0.340754065046083
GO:0031435	mitogen-activated protein kinase kinase kinase binding	7/4842	16/18639	0.4375	1.68413104089219	0.0946666600326586	0.340754065046083
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	7/4842	16/18639	0.4375	1.68413104089219	0.0946666600326586	0.340754065046083
GO:0140328	floppase activity	7/4842	16/18639	0.4375	1.68413104089219	0.0946666600326586	0.340754065046083
GO:0004519	endonuclease activity	40/4842	127/18639	0.31496062992126	1.21242279659281	0.0949022680943799	0.340754065046083
GO:0003725	double-stranded RNA binding	25/4842	75/18639	0.333333333333333	1.28314745972739	0.0949889650349702	0.340754065046083
GO:0005154	epidermal growth factor receptor binding	13/4842	35/18639	0.371428571428571	1.42979288369623	0.0971726693982181	0.34675299922101
GO:0140566	histone reader activity	13/4842	35/18639	0.371428571428571	1.42979288369623	0.0971726693982181	0.34675299922101
GO:0016407	acetyltransferase activity	31/4842	96/18639	0.322916666666667	1.2430491016109	0.0990355766711078	0.352473076026305
GO:0004715	non-membrane spanning protein tyrosine kinase activity	16/4842	45/18639	0.355555555555556	1.36869062370921	0.0998586981380832	0.353546722389663
GO:0141110	transporter inhibitor activity	16/4842	45/18639	0.355555555555556	1.36869062370921	0.0998586981380832	0.353546722389663
GO:0005518	collagen binding	24/4842	72/18639	0.333333333333333	1.28314745972739	0.10032255134766	0.353647478614054
GO:0140098	catalytic activity, acting on RNA	112/4842	387/18639	0.289405684754522	1.11405050767029	0.100408760520952	0.353647478614054
GO:0071813	lipoprotein particle binding	12/4842	32/18639	0.375	1.44354089219331	0.101993476820259	0.357372492424474
GO:0071814	protein-lipid complex binding	12/4842	32/18639	0.375	1.44354089219331	0.101993476820259	0.357372492424474
GO:0030159	signaling receptor complex adaptor activity	18/4842	52/18639	0.346153846153846	1.33249928510152	0.105253168194681	0.367305823259087
GO:0004520	DNA endonuclease activity	15/4842	42/18639	0.357142857142857	1.37480084970791	0.105370180861198	0.367305823259087
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	11/4842	29/18639	0.379310344827586	1.46013331624151	0.106951606043899	0.369023862075131
GO:0043236	laminin binding	11/4842	29/18639	0.379310344827586	1.46013331624151	0.106951606043899	0.369023862075131
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	11/4842	29/18639	0.379310344827586	1.46013331624151	0.106951606043899	0.369023862075131
GO:0097472	cyclin-dependent protein kinase activity	11/4842	29/18639	0.379310344827586	1.46013331624151	0.106951606043899	0.369023862075131
GO:0019210	kinase inhibitor activity	29/4842	90/18639	0.322222222222222	1.24037587773647	0.110202832738225	0.379276754297039
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	14/4842	39/18639	0.358974358974359	1.38185111047565	0.111216195518492	0.381795344615381
GO:0030507	spectrin binding	10/4842	26/18639	0.384615384615385	1.48055476122391	0.11199130781807	0.381830313609811
GO:0034237	protein kinase A regulatory subunit binding	10/4842	26/18639	0.384615384615385	1.48055476122391	0.11199130781807	0.381830313609811
GO:0008235	metalloexopeptidase activity	22/4842	66/18639	0.333333333333333	1.28314745972739	0.112071139245358	0.381830313609811
GO:0019212	phosphatase inhibitor activity	19/4842	56/18639	0.339285714285714	1.30606080722252	0.115529095616762	0.391643634140823
GO:0030170	pyridoxal phosphate binding	19/4842	56/18639	0.339285714285714	1.30606080722252	0.115529095616762	0.391643634140823
GO:0000295	adenine nucleotide transmembrane transporter activity	9/4842	23/18639	0.391304347826087	1.50630353967997	0.117016527367982	0.39373303005207
GO:0003887	DNA-directed DNA polymerase activity	9/4842	23/18639	0.391304347826087	1.50630353967997	0.117016527367982	0.39373303005207
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	9/4842	23/18639	0.391304347826087	1.50630353967997	0.117016527367982	0.39373303005207
GO:0004857	enzyme inhibitor activity	119/4842	416/18639	0.286057692307692	1.10116260366028	0.119682985187637	0.401708237411968
GO:0016408	C-acyltransferase activity	8/4842	20/18639	0.4	1.53977695167286	0.121861436630856	0.407005192294188
GO:0031418	L-ascorbic acid binding	8/4842	20/18639	0.4	1.53977695167286	0.121861436630856	0.407005192294188
GO:0004864	protein phosphatase inhibitor activity	18/4842	53/18639	0.339622641509434	1.3073577891562	0.122294834018557	0.407449127590081
GO:0071889	14-3-3 protein binding	12/4842	33/18639	0.363636363636364	1.39979722879351	0.123985903285768	0.410470453524232
GO:0140416	transcription regulator inhibitor activity	12/4842	33/18639	0.363636363636364	1.39979722879351	0.123985903285768	0.410470453524232
GO:0048156	tau protein binding	15/4842	43/18639	0.348837209302326	1.34282873692401	0.124602065982871	0.410470453524232
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	7/4842	17/18639	0.411764705882353	1.58506450907501	0.126233305142649	0.410470453524232
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	7/4842	17/18639	0.411764705882353	1.58506450907501	0.126233305142649	0.410470453524232
GO:0030169	low-density lipoprotein particle binding	7/4842	17/18639	0.411764705882353	1.58506450907501	0.126233305142649	0.410470453524232
GO:0032183	SUMO binding	7/4842	17/18639	0.411764705882353	1.58506450907501	0.126233305142649	0.410470453524232
GO:0032977	membrane insertase activity	7/4842	17/18639	0.411764705882353	1.58506450907501	0.126233305142649	0.410470453524232
GO:0004386	helicase activity	47/4842	155/18639	0.303225806451613	1.16725026981652	0.126544217503082	0.410470453524232
GO:0008474	palmitoyl-(protein) hydrolase activity	6/4842	14/18639	0.428571428571429	1.6497610196495	0.129592765756535	0.410470453524232
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	6/4842	14/18639	0.428571428571429	1.6497610196495	0.129592765756535	0.410470453524232
GO:0019763	immunoglobulin receptor activity	6/4842	14/18639	0.428571428571429	1.6497610196495	0.129592765756535	0.410470453524232
GO:0034236	protein kinase A catalytic subunit binding	6/4842	14/18639	0.428571428571429	1.6497610196495	0.129592765756535	0.410470453524232
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	6/4842	14/18639	0.428571428571429	1.6497610196495	0.129592765756535	0.410470453524232
GO:0042813	Wnt receptor activity	6/4842	14/18639	0.428571428571429	1.6497610196495	0.129592765756535	0.410470453524232
GO:0044548	S100 protein binding	6/4842	14/18639	0.428571428571429	1.6497610196495	0.129592765756535	0.410470453524232
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	6/4842	14/18639	0.428571428571429	1.6497610196495	0.129592765756535	0.410470453524232
GO:0098599	palmitoyl hydrolase activity	6/4842	14/18639	0.428571428571429	1.6497610196495	0.129592765756535	0.410470453524232
GO:0016176	superoxide-generating NADPH oxidase activator activity	5/4842	11/18639	0.454545454545455	1.74974653599189	0.130875373818272	0.410470453524232
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	5/4842	11/18639	0.454545454545455	1.74974653599189	0.130875373818272	0.410470453524232
GO:0019864	IgG binding	5/4842	11/18639	0.454545454545455	1.74974653599189	0.130875373818272	0.410470453524232
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	5/4842	11/18639	0.454545454545455	1.74974653599189	0.130875373818272	0.410470453524232
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	5/4842	11/18639	0.454545454545455	1.74974653599189	0.130875373818272	0.410470453524232
GO:0048185	activin binding	5/4842	11/18639	0.454545454545455	1.74974653599189	0.130875373818272	0.410470453524232
GO:0051721	protein phosphatase 2A binding	11/4842	30/18639	0.366666666666667	1.41146220570012	0.130940123686056	0.410470453524232
GO:0004177	aminopeptidase activity	14/4842	40/18639	0.35	1.34730483271375	0.131980175321951	0.410470453524232
GO:0015036	disulfide oxidoreductase activity	14/4842	40/18639	0.35	1.34730483271375	0.131980175321951	0.410470453524232
GO:0061791	GTPase motor activity	14/4842	40/18639	0.35	1.34730483271375	0.131980175321951	0.410470453524232
GO:1990606	membrane scission GTPase motor activity	14/4842	40/18639	0.35	1.34730483271375	0.131980175321951	0.410470453524232
GO:0016504	peptidase activator activity	19/4842	57/18639	0.333333333333333	1.28314745972739	0.132904136039745	0.411456640342224
GO:0070279	vitamin B6 binding	19/4842	57/18639	0.333333333333333	1.28314745972739	0.132904136039745	0.411456640342224
GO:0008013	beta-catenin binding	33/4842	106/18639	0.311320754716981	1.19841130672652	0.135754104671444	0.419322473654848
GO:0140359	ABC-type transporter activity	16/4842	47/18639	0.340425531914894	1.31044846950882	0.137335364424875	0.423242623091205
GO:0050661	NADP binding	18/4842	54/18639	0.333333333333333	1.28314745972739	0.14087206728346	0.433157649062066
GO:0003774	cytoskeletal motor activity	46/4842	153/18639	0.300653594771242	1.15734868916588	0.143727739563184	0.440938495130493
GO:0019003	GDP binding	24/4842	75/18639	0.32	1.23182156133829	0.144986028535849	0.440940765567076
GO:0016248	channel inhibitor activity	15/4842	44/18639	0.340909090909091	1.31230990199392	0.14571629249123	0.440940765567076
GO:0015295	solute:proton symporter activity	9/4842	24/18639	0.375	1.44354089219331	0.146004722521842	0.440940765567076
GO:0042625	ATPase-coupled ion transmembrane transporter activity	9/4842	24/18639	0.375	1.44354089219331	0.146004722521842	0.440940765567076
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	9/4842	24/18639	0.375	1.44354089219331	0.146004722521842	0.440940765567076
GO:0046961	proton-transporting ATPase activity, rotational mechanism	9/4842	24/18639	0.375	1.44354089219331	0.146004722521842	0.440940765567076
GO:0050431	transforming growth factor beta binding	9/4842	24/18639	0.375	1.44354089219331	0.146004722521842	0.440940765567076
GO:0005010	insulin-like growth factor receptor activity	17/4842	51/18639	0.333333333333333	1.28314745972739	0.149439579089035	0.44931279211692
GO:0030544	Hsp70 protein binding	17/4842	51/18639	0.333333333333333	1.28314745972739	0.149439579089035	0.44931279211692
GO:0051219	phosphoprotein binding	29/4842	93/18639	0.311827956989247	1.2003637526482	0.151845792359296	0.455537377077888
GO:0000287	magnesium ion binding	67/4842	230/18639	0.291304347826087	1.12135930176176	0.153579707736048	0.459722039050952
GO:1902936	phosphatidylinositol bisphosphate binding	34/4842	111/18639	0.306306306306306	1.17910847650625	0.155593512926104	0.464724236845368
GO:0016878	acid-thiol ligase activity	11/4842	31/18639	0.354838709677419	1.36593116680657	0.157581571056172	0.469627715059711
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	16/4842	48/18639	0.333333333333333	1.28314745972739	0.158671831733421	0.471839920680962
GO:0017128	phospholipid scramblase activity	7/4842	18/18639	0.388888888888889	1.49700536968195	0.162351673027331	0.479702356457721
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	7/4842	18/18639	0.388888888888889	1.49700536968195	0.162351673027331	0.479702356457721
GO:0016279	protein-lysine N-methyltransferase activity	22/4842	69/18639	0.318840579710145	1.22735843973924	0.16237712508414	0.479702356457721
GO:0097718	disordered domain specific binding	10/4842	28/18639	0.357142857142857	1.37480084970791	0.16748269157349	0.493709847334026
GO:0004467	long-chain fatty acid-CoA ligase activity	6/4842	15/18639	0.4	1.53977695167286	0.170641850257449	0.495176286172296
GO:0005041	low-density lipoprotein particle receptor activity	6/4842	15/18639	0.4	1.53977695167286	0.170641850257449	0.495176286172296
GO:0010181	FMN binding	6/4842	15/18639	0.4	1.53977695167286	0.170641850257449	0.495176286172296
GO:0015929	hexosaminidase activity	6/4842	15/18639	0.4	1.53977695167286	0.170641850257449	0.495176286172296
GO:0042809	nuclear vitamin D receptor binding	6/4842	15/18639	0.4	1.53977695167286	0.170641850257449	0.495176286172296
GO:0061578	K63-linked deubiquitinase activity	6/4842	15/18639	0.4	1.53977695167286	0.170641850257449	0.495176286172296
GO:0140776	protein-containing complex destabilizing activity	6/4842	15/18639	0.4	1.53977695167286	0.170641850257449	0.495176286172296
GO:0005080	protein kinase C binding	17/4842	52/18639	0.326923076923077	1.25847154704032	0.170901550094863	0.495176286172296
GO:0004879	nuclear receptor activity	19/4842	59/18639	0.322033898305085	1.23965093566883	0.171894881639078	0.496599262250992
GO:0008170	N-methyltransferase activity	30/4842	98/18639	0.306122448979592	1.17840072832107	0.174593123293892	0.496599262250992
GO:0008139	nuclear localization sequence binding	9/4842	25/18639	0.36	1.38579925650558	0.178197736672565	0.496599262250992
GO:0005247	voltage-gated chloride channel activity	5/4842	12/18639	0.416666666666667	1.60393432465923	0.178413166452542	0.496599262250992
GO:0008603	cAMP-dependent protein kinase regulator activity	5/4842	12/18639	0.416666666666667	1.60393432465923	0.178413166452542	0.496599262250992
GO:0016423	tRNA (guanine) methyltransferase activity	5/4842	12/18639	0.416666666666667	1.60393432465923	0.178413166452542	0.496599262250992
GO:0016801	hydrolase activity, acting on ether bonds	5/4842	12/18639	0.416666666666667	1.60393432465923	0.178413166452542	0.496599262250992
GO:0016803	ether hydrolase activity	5/4842	12/18639	0.416666666666667	1.60393432465923	0.178413166452542	0.496599262250992
GO:0016840	carbon-nitrogen lyase activity	5/4842	12/18639	0.416666666666667	1.60393432465923	0.178413166452542	0.496599262250992
GO:0017166	vinculin binding	5/4842	12/18639	0.416666666666667	1.60393432465923	0.178413166452542	0.496599262250992
GO:0031543	peptidyl-proline dioxygenase activity	5/4842	12/18639	0.416666666666667	1.60393432465923	0.178413166452542	0.496599262250992
GO:0035014	phosphatidylinositol 3-kinase regulator activity	5/4842	12/18639	0.416666666666667	1.60393432465923	0.178413166452542	0.496599262250992
GO:0035197	siRNA binding	5/4842	12/18639	0.416666666666667	1.60393432465923	0.178413166452542	0.496599262250992
GO:0035251	UDP-glucosyltransferase activity	5/4842	12/18639	0.416666666666667	1.60393432465923	0.178413166452542	0.496599262250992
GO:0035259	nuclear glucocorticoid receptor binding	5/4842	12/18639	0.416666666666667	1.60393432465923	0.178413166452542	0.496599262250992
GO:0035497	cAMP response element binding	5/4842	12/18639	0.416666666666667	1.60393432465923	0.178413166452542	0.496599262250992
GO:0097677	STAT family protein binding	5/4842	12/18639	0.416666666666667	1.60393432465923	0.178413166452542	0.496599262250992
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	5/4842	12/18639	0.416666666666667	1.60393432465923	0.178413166452542	0.496599262250992
GO:0004527	exonuclease activity	26/4842	84/18639	0.30952380952381	1.19149406974686	0.178573389312139	0.496599262250992
GO:0019783	ubiquitin-like protein peptidase activity	38/4842	127/18639	0.299212598425197	1.15180165676316	0.17926318679819	0.496599262250992
GO:0042826	histone deacetylase binding	38/4842	127/18639	0.299212598425197	1.15180165676316	0.17926318679819	0.496599262250992
GO:0035198	miRNA binding	14/4842	42/18639	0.333333333333333	1.28314745972739	0.179449585916656	0.496599262250992
GO:0016278	lysine N-methyltransferase activity	22/4842	70/18639	0.314285714285714	1.20982474774296	0.181507520034754	0.501271277326123
GO:0008168	methyltransferase activity	59/4842	204/18639	0.28921568627451	1.11331911946935	0.187629094037369	0.517124088444456
GO:0015101	organic cation transmembrane transporter activity	25/4842	81/18639	0.308641975308642	1.18809949974758	0.188642764665189	0.518863263460438
GO:0008173	RNA methyltransferase activity	21/4842	67/18639	0.313432835820896	1.2065416412362	0.192257285057332	0.527198508102806
GO:0030291	protein serine/threonine kinase inhibitor activity	15/4842	46/18639	0.326086956521739	1.25525294973331	0.193288373458351	0.527198508102806
GO:0004714	transmembrane receptor protein tyrosine kinase activity	19/4842	60/18639	0.316666666666667	1.21899008674102	0.193404410299546	0.527198508102806
GO:0098531	ligand-modulated transcription factor activity	19/4842	60/18639	0.316666666666667	1.21899008674102	0.193404410299546	0.527198508102806
GO:0038064	collagen receptor activity	17/4842	53/18639	0.320754716981132	1.23472680086975	0.193854721575341	0.527198508102806
GO:0052689	carboxylic ester hydrolase activity	28/4842	92/18639	0.304347826086957	1.17156941975109	0.194005940666151	0.527198508102806
GO:0070851	growth factor receptor binding	41/4842	139/18639	0.294964028776978	1.13544703270841	0.195796556367787	0.531000260869439
GO:0019842	vitamin binding	44/4842	150/18639	0.293333333333333	1.1291697645601	0.197189046977783	0.533473238610166
GO:0004540	RNA nuclease activity	36/4842	121/18639	0.297520661157025	1.14528864174015	0.197495255001699	0.533473238610166
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	7/4842	19/18639	0.368421052631579	1.4182156133829	0.202461856663407	0.5447188048325
GO:0097001	ceramide binding	7/4842	19/18639	0.368421052631579	1.4182156133829	0.202461856663407	0.5447188048325
GO:0004536	DNA nuclease activity	20/4842	64/18639	0.3125	1.20295074349442	0.203781467729725	0.546709173524955
GO:0044390	ubiquitin-like protein conjugating enzyme binding	12/4842	36/18639	0.333333333333333	1.28314745972739	0.204007995430403	0.546709173524955
GO:0008200	ion channel inhibitor activity	14/4842	43/18639	0.325581395348837	1.25330682112907	0.205927698988139	0.549245491942136
GO:0005017	platelet-derived growth factor receptor activity	16/4842	50/18639	0.32	1.23182156133829	0.206169583627247	0.549245491942136
GO:0005019	platelet-derived growth factor beta-receptor activity	16/4842	50/18639	0.32	1.23182156133829	0.206169583627247	0.549245491942136
GO:0005160	transforming growth factor beta receptor binding	9/4842	26/18639	0.346153846153846	1.33249928510152	0.213248199007298	0.562576960805245
GO:0005227	calcium-activated cation channel activity	9/4842	26/18639	0.346153846153846	1.33249928510152	0.213248199007298	0.562576960805245
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	9/4842	26/18639	0.346153846153846	1.33249928510152	0.213248199007298	0.562576960805245
GO:0019865	immunoglobulin binding	9/4842	26/18639	0.346153846153846	1.33249928510152	0.213248199007298	0.562576960805245
GO:0097602	cullin family protein binding	9/4842	26/18639	0.346153846153846	1.33249928510152	0.213248199007298	0.562576960805245
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	6/4842	16/18639	0.375	1.44354089219331	0.216226964392323	0.56385339176152
GO:0005521	lamin binding	6/4842	16/18639	0.375	1.44354089219331	0.216226964392323	0.56385339176152
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	6/4842	16/18639	0.375	1.44354089219331	0.216226964392323	0.56385339176152
GO:0022841	potassium ion leak channel activity	6/4842	16/18639	0.375	1.44354089219331	0.216226964392323	0.56385339176152
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	6/4842	16/18639	0.375	1.44354089219331	0.216226964392323	0.56385339176152
GO:0070411	I-SMAD binding	6/4842	16/18639	0.375	1.44354089219331	0.216226964392323	0.56385339176152
GO:0019239	deaminase activity	11/4842	33/18639	0.333333333333333	1.28314745972739	0.218055764698161	0.566443710595223
GO:0140311	protein sequestering activity	11/4842	33/18639	0.333333333333333	1.28314745972739	0.218055764698161	0.566443710595223
GO:0061749	forked DNA-dependent helicase activity	15/4842	47/18639	0.319148936170213	1.22854544016452	0.219516346442793	0.56746276207965
GO:1990518	single-stranded 3'-5' DNA helicase activity	15/4842	47/18639	0.319148936170213	1.22854544016452	0.219516346442793	0.56746276207965
GO:0004532	RNA exonuclease activity	13/4842	40/18639	0.325	1.2510687732342	0.219703503017563	0.56746276207965
GO:0160215	deacylase activity	20/4842	65/18639	0.307692307692308	1.18444380897913	0.226381353420337	0.57843447823699
GO:0008171	O-methyltransferase activity	8/4842	23/18639	0.347826086956522	1.33893647971553	0.228651662035801	0.57843447823699
GO:0017134	fibroblast growth factor binding	8/4842	23/18639	0.347826086956522	1.33893647971553	0.228651662035801	0.57843447823699
GO:0044013	histone H2B acetyltransferase activity	8/4842	23/18639	0.347826086956522	1.33893647971553	0.228651662035801	0.57843447823699
GO:0008408	3'-5' exonuclease activity	18/4842	58/18639	0.310344827586207	1.19465453147032	0.229465533826486	0.57843447823699
GO:0061980	regulatory RNA binding	18/4842	58/18639	0.310344827586207	1.19465453147032	0.229465533826486	0.57843447823699
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	48/4842	167/18639	0.287425149700599	1.10642655210026	0.230794086881842	0.57843447823699
GO:0042562	hormone binding	28/4842	94/18639	0.297872340425532	1.14664241082022	0.231115496265665	0.57843447823699
GO:0004535	poly(A)-specific ribonuclease activity	5/4842	13/18639	0.384615384615385	1.48055476122391	0.231203161655198	0.57843447823699
GO:0005172	vascular endothelial growth factor receptor binding	5/4842	13/18639	0.384615384615385	1.48055476122391	0.231203161655198	0.57843447823699
GO:0008035	high-density lipoprotein particle binding	5/4842	13/18639	0.384615384615385	1.48055476122391	0.231203161655198	0.57843447823699
GO:0015651	quaternary ammonium group transmembrane transporter activity	5/4842	13/18639	0.384615384615385	1.48055476122391	0.231203161655198	0.57843447823699
GO:0019855	calcium channel inhibitor activity	5/4842	13/18639	0.384615384615385	1.48055476122391	0.231203161655198	0.57843447823699
GO:0043560	insulin receptor substrate binding	5/4842	13/18639	0.384615384615385	1.48055476122391	0.231203161655198	0.57843447823699
GO:0051011	microtubule minus-end binding	5/4842	13/18639	0.384615384615385	1.48055476122391	0.231203161655198	0.57843447823699
GO:0061459	L-arginine transmembrane transporter activity	5/4842	13/18639	0.384615384615385	1.48055476122391	0.231203161655198	0.57843447823699
GO:0140852	histone ubiquitin ligase activity	5/4842	13/18639	0.384615384615385	1.48055476122391	0.231203161655198	0.57843447823699
GO:0005030	neurotrophin receptor activity	16/4842	51/18639	0.313725490196078	1.20766819739048	0.232103299987573	0.579617080631949
GO:0070566	adenylyltransferase activity	10/4842	30/18639	0.333333333333333	1.28314745972739	0.233541674619516	0.582136968353057
GO:0019213	deacetylase activity	12/4842	37/18639	0.324324324324324	1.24846779865367	0.234780733711532	0.584151697087776
GO:0002039	p53 binding	21/4842	69/18639	0.304347826086957	1.17156941975109	0.236065454109841	0.585200650407577
GO:0008080	N-acetyltransferase activity	21/4842	69/18639	0.304347826086957	1.17156941975109	0.236065454109841	0.585200650407577
GO:0016004	phospholipase activator activity	7/4842	20/18639	0.35	1.34730483271375	0.245862082834781	0.589475352677161
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	7/4842	20/18639	0.35	1.34730483271375	0.245862082834781	0.589475352677161
GO:0009378	four-way junction helicase activity	15/4842	48/18639	0.3125	1.20295074349442	0.247172944037962	0.589475352677161
GO:0036121	double-stranded DNA helicase activity	15/4842	48/18639	0.3125	1.20295074349442	0.247172944037962	0.589475352677161
GO:0043138	3'-5' DNA helicase activity	15/4842	48/18639	0.3125	1.20295074349442	0.247172944037962	0.589475352677161
GO:0140693	molecular condensate scaffold activity	15/4842	48/18639	0.3125	1.20295074349442	0.247172944037962	0.589475352677161
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	4/4842	10/18639	0.4	1.53977695167286	0.247353595629281	0.589475352677161
GO:0004382	GDP phosphatase activity	4/4842	10/18639	0.4	1.53977695167286	0.247353595629281	0.589475352677161
GO:0004445	inositol-polyphosphate 5-phosphatase activity	4/4842	10/18639	0.4	1.53977695167286	0.247353595629281	0.589475352677161
GO:0004862	cAMP-dependent protein kinase inhibitor activity	4/4842	10/18639	0.4	1.53977695167286	0.247353595629281	0.589475352677161
GO:0004955	prostaglandin receptor activity	4/4842	10/18639	0.4	1.53977695167286	0.247353595629281	0.589475352677161
GO:0008140	cAMP response element binding protein binding	4/4842	10/18639	0.4	1.53977695167286	0.247353595629281	0.589475352677161
GO:0008239	dipeptidyl-peptidase activity	4/4842	10/18639	0.4	1.53977695167286	0.247353595629281	0.589475352677161
GO:0015924	mannosyl-oligosaccharide mannosidase activity	4/4842	10/18639	0.4	1.53977695167286	0.247353595629281	0.589475352677161
GO:0031419	cobalamin binding	4/4842	10/18639	0.4	1.53977695167286	0.247353595629281	0.589475352677161
GO:0031434	mitogen-activated protein kinase kinase binding	4/4842	10/18639	0.4	1.53977695167286	0.247353595629281	0.589475352677161
GO:0031957	very long-chain fatty acid-CoA ligase activity	4/4842	10/18639	0.4	1.53977695167286	0.247353595629281	0.589475352677161
GO:0043295	glutathione binding	4/4842	10/18639	0.4	1.53977695167286	0.247353595629281	0.589475352677161
GO:0050308	sugar-phosphatase activity	4/4842	10/18639	0.4	1.53977695167286	0.247353595629281	0.589475352677161
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	4/4842	10/18639	0.4	1.53977695167286	0.247353595629281	0.589475352677161
GO:0070739	protein-glutamic acid ligase activity	4/4842	10/18639	0.4	1.53977695167286	0.247353595629281	0.589475352677161
GO:0070740	tubulin-glutamic acid ligase activity	4/4842	10/18639	0.4	1.53977695167286	0.247353595629281	0.589475352677161
GO:0001727	lipid kinase activity	13/4842	41/18639	0.317073170731707	1.22055490071629	0.249857491501567	0.59381502665732
GO:0004364	glutathione transferase activity	9/4842	27/18639	0.333333333333333	1.28314745972739	0.250730602719423	0.59381502665732
GO:0008276	protein methyltransferase activity	28/4842	95/18639	0.294736842105263	1.13457249070632	0.250798788359847	0.59381502665732
GO:0015035	protein-disulfide reductase activity	11/4842	34/18639	0.323529411764706	1.24540782855893	0.251364177950812	0.59381502665732
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	11/4842	34/18639	0.323529411764706	1.24540782855893	0.251364177950812	0.59381502665732
GO:0003724	RNA helicase activity	23/4842	77/18639	0.298701298701299	1.14983343793753	0.253995973636051	0.598988765653017
GO:0016779	nucleotidyltransferase activity	39/4842	136/18639	0.286764705882353	1.10388421167724	0.263853943062696	0.620286804471982
GO:1901682	sulfur compound transmembrane transporter activity	19/4842	63/18639	0.301587301587302	1.16094293975335	0.264981315631834	0.620286804471982
GO:0045125	bioactive lipid receptor activity	6/4842	17/18639	0.352941176470588	1.35862672206429	0.265314414892146	0.620286804471982
GO:0048038	quinone binding	6/4842	17/18639	0.352941176470588	1.35862672206429	0.265314414892146	0.620286804471982
GO:1990226	histone methyltransferase binding	6/4842	17/18639	0.352941176470588	1.35862672206429	0.265314414892146	0.620286804471982
GO:0000146	microfilament motor activity	12/4842	38/18639	0.315789473684211	1.21561338289963	0.267202143339706	0.621485602690637
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	12/4842	38/18639	0.315789473684211	1.21561338289963	0.267202143339706	0.621485602690637
GO:0042162	telomeric DNA binding	12/4842	38/18639	0.315789473684211	1.21561338289963	0.267202143339706	0.621485602690637
GO:0043998	histone H2A acetyltransferase activity	8/4842	24/18639	0.333333333333333	1.28314745972739	0.269975131792782	0.622902496935409
GO:0050699	WW domain binding	8/4842	24/18639	0.333333333333333	1.28314745972739	0.269975131792782	0.622902496935409
GO:0070300	phosphatidic acid binding	8/4842	24/18639	0.333333333333333	1.28314745972739	0.269975131792782	0.622902496935409
GO:0070840	dynein complex binding	8/4842	24/18639	0.333333333333333	1.28314745972739	0.269975131792782	0.622902496935409
GO:0004175	endopeptidase activity	111/4842	405/18639	0.274074074074074	1.05503235577585	0.270421335679394	0.622902496935409
GO:0042054	histone methyltransferase activity	20/4842	67/18639	0.298507462686567	1.14908727736781	0.274607606348664	0.622902496935409
GO:0005004	GPI-linked ephrin receptor activity	15/4842	49/18639	0.306122448979592	1.17840072832107	0.276079941488334	0.622902496935409
GO:0005008	hepatocyte growth factor receptor activity	15/4842	49/18639	0.306122448979592	1.17840072832107	0.276079941488334	0.622902496935409
GO:0005009	insulin receptor activity	15/4842	49/18639	0.306122448979592	1.17840072832107	0.276079941488334	0.622902496935409
GO:0005011	macrophage colony-stimulating factor receptor activity	15/4842	49/18639	0.306122448979592	1.17840072832107	0.276079941488334	0.622902496935409
GO:0005018	platelet-derived growth factor alpha-receptor activity	15/4842	49/18639	0.306122448979592	1.17840072832107	0.276079941488334	0.622902496935409
GO:0005020	stem cell factor receptor activity	15/4842	49/18639	0.306122448979592	1.17840072832107	0.276079941488334	0.622902496935409
GO:0008288	boss receptor activity	15/4842	49/18639	0.306122448979592	1.17840072832107	0.276079941488334	0.622902496935409
GO:0016763	pentosyltransferase activity	15/4842	49/18639	0.306122448979592	1.17840072832107	0.276079941488334	0.622902496935409
GO:0036332	placental growth factor receptor activity	15/4842	49/18639	0.306122448979592	1.17840072832107	0.276079941488334	0.622902496935409
GO:0038062	protein tyrosine kinase collagen receptor activity	15/4842	49/18639	0.306122448979592	1.17840072832107	0.276079941488334	0.622902496935409
GO:0060175	brain-derived neurotrophic factor receptor activity	15/4842	49/18639	0.306122448979592	1.17840072832107	0.276079941488334	0.622902496935409
GO:0060590	ATPase regulator activity	15/4842	49/18639	0.306122448979592	1.17840072832107	0.276079941488334	0.622902496935409
GO:0061134	peptidase regulator activity	63/4842	226/18639	0.278761061946903	1.07307464552423	0.278846443510654	0.628099298007386
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	18/4842	60/18639	0.3	1.15483271375465	0.281027330298775	0.631961956691774
GO:0000175	3'-5'-RNA exonuclease activity	11/4842	35/18639	0.314285714285714	1.20982474774296	0.286298476214784	0.636309927321547
GO:0016229	steroid dehydrogenase activity	11/4842	35/18639	0.314285714285714	1.20982474774296	0.286298476214784	0.636309927321547
GO:0005003	ephrin receptor activity	16/4842	53/18639	0.30188679245283	1.16209581258329	0.287606501995428	0.636309927321547
GO:0005005	transmembrane-ephrin receptor activity	16/4842	53/18639	0.30188679245283	1.16209581258329	0.287606501995428	0.636309927321547
GO:0008174	mRNA methyltransferase activity	5/4842	14/18639	0.357142857142857	1.37480084970791	0.2876533815989	0.636309927321547
GO:0008559	ABC-type xenobiotic transporter activity	5/4842	14/18639	0.357142857142857	1.37480084970791	0.2876533815989	0.636309927321547
GO:0015926	glucosidase activity	5/4842	14/18639	0.357142857142857	1.37480084970791	0.2876533815989	0.636309927321547
GO:0019992	diacylglycerol binding	5/4842	14/18639	0.357142857142857	1.37480084970791	0.2876533815989	0.636309927321547
GO:0030983	mismatched DNA binding	5/4842	14/18639	0.357142857142857	1.37480084970791	0.2876533815989	0.636309927321547
GO:0070742	C2H2 zinc finger domain binding	5/4842	14/18639	0.357142857142857	1.37480084970791	0.2876533815989	0.636309927321547
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	37/4842	130/18639	0.284615384615385	1.09561052330569	0.28822065679616	0.63652640165406
GO:0001846	opsonin binding	7/4842	21/18639	0.333333333333333	1.28314745972739	0.291762101828145	0.641214603045324
GO:0005123	death receptor binding	7/4842	21/18639	0.333333333333333	1.28314745972739	0.291762101828145	0.641214603045324
GO:0015174	basic amino acid transmembrane transporter activity	7/4842	21/18639	0.333333333333333	1.28314745972739	0.291762101828145	0.641214603045324
GO:0008186	ATP-dependent activity, acting on RNA	23/4842	79/18639	0.291139240506329	1.12072373064797	0.30039677618062	0.659123023464272
GO:0005006	epidermal growth factor receptor activity	15/4842	50/18639	0.3	1.15483271375465	0.3060415234288	0.664064676803219
GO:0005007	fibroblast growth factor receptor activity	15/4842	50/18639	0.3	1.15483271375465	0.3060415234288	0.664064676803219
GO:0008378	galactosyltransferase activity	10/4842	32/18639	0.3125	1.20295074349442	0.307446792633849	0.664064676803219
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	10/4842	32/18639	0.3125	1.20295074349442	0.307446792633849	0.664064676803219
GO:0042910	xenobiotic transmembrane transporter activity	10/4842	32/18639	0.3125	1.20295074349442	0.307446792633849	0.664064676803219
GO:0043425	bHLH transcription factor binding	10/4842	32/18639	0.3125	1.20295074349442	0.307446792633849	0.664064676803219
GO:0051059	NF-kappaB binding	10/4842	32/18639	0.3125	1.20295074349442	0.307446792633849	0.664064676803219
GO:0140142	nucleocytoplasmic carrier activity	10/4842	32/18639	0.3125	1.20295074349442	0.307446792633849	0.664064676803219
GO:0015026	coreceptor activity	18/4842	61/18639	0.295081967213115	1.1359010299226	0.308182969589709	0.664064676803219
GO:0031406	carboxylic acid binding	52/4842	187/18639	0.27807486631016	1.07043317495974	0.308712289283424	0.664064676803219
GO:0003707	nuclear steroid receptor activity	8/4842	25/18639	0.32	1.23182156133829	0.313164494202295	0.664064676803219
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	4/4842	11/18639	0.363636363636364	1.39979722879351	0.313912579521286	0.664064676803219
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	4/4842	11/18639	0.363636363636364	1.39979722879351	0.313912579521286	0.664064676803219
GO:0001851	complement component C3b binding	4/4842	11/18639	0.363636363636364	1.39979722879351	0.313912579521286	0.664064676803219
GO:0004954	prostanoid receptor activity	4/4842	11/18639	0.363636363636364	1.39979722879351	0.313912579521286	0.664064676803219
GO:0019203	carbohydrate phosphatase activity	4/4842	11/18639	0.363636363636364	1.39979722879351	0.313912579521286	0.664064676803219
GO:0019215	intermediate filament binding	4/4842	11/18639	0.363636363636364	1.39979722879351	0.313912579521286	0.664064676803219
GO:0032050	clathrin heavy chain binding	4/4842	11/18639	0.363636363636364	1.39979722879351	0.313912579521286	0.664064676803219
GO:0032404	mismatch repair complex binding	4/4842	11/18639	0.363636363636364	1.39979722879351	0.313912579521286	0.664064676803219
GO:0097493	structural molecule activity conferring elasticity	4/4842	11/18639	0.363636363636364	1.39979722879351	0.313912579521286	0.664064676803219
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	4/4842	11/18639	0.363636363636364	1.39979722879351	0.313912579521286	0.664064676803219
GO:0180030	inositol phosphate kinase activity	4/4842	11/18639	0.363636363636364	1.39979722879351	0.313912579521286	0.664064676803219
GO:1900750	oligopeptide binding	4/4842	11/18639	0.363636363636364	1.39979722879351	0.313912579521286	0.664064676803219
GO:0008409	5'-3' exonuclease activity	6/4842	18/18639	0.333333333333333	1.28314745972739	0.316795785824553	0.667042058351077
GO:0017075	syntaxin-1 binding	6/4842	18/18639	0.333333333333333	1.28314745972739	0.316795785824553	0.667042058351077
GO:0032393	MHC class I receptor activity	6/4842	18/18639	0.333333333333333	1.28314745972739	0.316795785824553	0.667042058351077
GO:0008237	metallopeptidase activity	51/4842	184/18639	0.277173913043478	1.06696500727332	0.320372236216211	0.673526747766174
GO:0004190	aspartic-type endopeptidase activity	11/4842	36/18639	0.305555555555556	1.1762185047501	0.322506287759911	0.676963662852073
GO:0001784	phosphotyrosine residue binding	14/4842	47/18639	0.297872340425532	1.14664241082022	0.326018306361886	0.683277934198945
GO:0044325	transmembrane transporter binding	38/4842	136/18639	0.279411764705882	1.0755794883009	0.330546300427292	0.683385792383409
GO:0035250	UDP-galactosyltransferase activity	9/4842	29/18639	0.310344827586207	1.19465453147032	0.331034023554633	0.683385792383409
GO:0015399	primary active transmembrane transporter activity	46/4842	166/18639	0.27710843373494	1.06671294844807	0.332181018853704	0.683385792383409
GO:0016741	transferase activity, transferring one-carbon groups	59/4842	215/18639	0.274418604651163	1.05635860638022	0.33571357805973	0.683385792383409
GO:0030331	nuclear estrogen receptor binding	12/4842	40/18639	0.3	1.15483271375465	0.335818209397271	0.683385792383409
GO:0015179	L-amino acid transmembrane transporter activity	18/4842	62/18639	0.290322580645161	1.11758004556901	0.336054912982258	0.683385792383409
GO:0016829	lyase activity	55/4842	200/18639	0.275	1.05859665427509	0.3361807060681	0.683385792383409
GO:0005021	vascular endothelial growth factor receptor activity	15/4842	51/18639	0.294117647058824	1.13218893505358	0.336849116529311	0.683385792383409
GO:0016830	carbon-carbon lyase activity	15/4842	51/18639	0.294117647058824	1.13218893505358	0.336849116529311	0.683385792383409
GO:0004407	histone deacetylase activity	7/4842	22/18639	0.318181818181818	1.22482257519432	0.339334126025146	0.683385792383409
GO:0008093	cytoskeletal anchor activity	7/4842	22/18639	0.318181818181818	1.22482257519432	0.339334126025146	0.683385792383409
GO:0032931	histone H3K56 acetyltransferase activity	7/4842	22/18639	0.318181818181818	1.22482257519432	0.339334126025146	0.683385792383409
GO:0033558	protein lysine deacetylase activity	7/4842	22/18639	0.318181818181818	1.22482257519432	0.339334126025146	0.683385792383409
GO:0043992	histone H3K9 acetyltransferase activity	7/4842	22/18639	0.318181818181818	1.22482257519432	0.339334126025146	0.683385792383409
GO:0043993	histone H3K18 acetyltransferase activity	7/4842	22/18639	0.318181818181818	1.22482257519432	0.339334126025146	0.683385792383409
GO:0043994	histone H3K23 acetyltransferase activity	7/4842	22/18639	0.318181818181818	1.22482257519432	0.339334126025146	0.683385792383409
GO:0043999	histone H2AK5 acetyltransferase activity	7/4842	22/18639	0.318181818181818	1.22482257519432	0.339334126025146	0.683385792383409
GO:0044012	histone H2AK9 acetyltransferase activity	7/4842	22/18639	0.318181818181818	1.22482257519432	0.339334126025146	0.683385792383409
GO:0044014	histone H2BK5 acetyltransferase activity	7/4842	22/18639	0.318181818181818	1.22482257519432	0.339334126025146	0.683385792383409
GO:0044015	histone H2BK12 acetyltransferase activity	7/4842	22/18639	0.318181818181818	1.22482257519432	0.339334126025146	0.683385792383409
GO:0044016	histone H3K4 acetyltransferase activity	7/4842	22/18639	0.318181818181818	1.22482257519432	0.339334126025146	0.683385792383409
GO:0044017	histone H3K27 acetyltransferase activity	7/4842	22/18639	0.318181818181818	1.22482257519432	0.339334126025146	0.683385792383409
GO:0044018	histone H3K36 acetyltransferase activity	7/4842	22/18639	0.318181818181818	1.22482257519432	0.339334126025146	0.683385792383409
GO:0046972	histone H4K16 acetyltransferase activity	7/4842	22/18639	0.318181818181818	1.22482257519432	0.339334126025146	0.683385792383409
GO:0140908	histone H3K122 acetyltransferase activity	7/4842	22/18639	0.318181818181818	1.22482257519432	0.339334126025146	0.683385792383409
GO:0043177	organic acid binding	52/4842	189/18639	0.275132275132275	1.05910583977498	0.340424961435869	0.683385792383409
GO:0000774	adenyl-nucleotide exchange factor activity	5/4842	15/18639	0.333333333333333	1.28314745972739	0.346159147269626	0.683385792383409
GO:0004953	icosanoid receptor activity	5/4842	15/18639	0.333333333333333	1.28314745972739	0.346159147269626	0.683385792383409
GO:0005402	carbohydrate:monoatomic cation symporter activity	5/4842	15/18639	0.333333333333333	1.28314745972739	0.346159147269626	0.683385792383409
GO:0008252	nucleotidase activity	5/4842	15/18639	0.333333333333333	1.28314745972739	0.346159147269626	0.683385792383409
GO:0016846	carbon-sulfur lyase activity	5/4842	15/18639	0.333333333333333	1.28314745972739	0.346159147269626	0.683385792383409
GO:0033130	acetylcholine receptor binding	5/4842	15/18639	0.333333333333333	1.28314745972739	0.346159147269626	0.683385792383409
GO:0045504	dynein heavy chain binding	5/4842	15/18639	0.333333333333333	1.28314745972739	0.346159147269626	0.683385792383409
GO:0048531	beta-1,3-galactosyltransferase activity	5/4842	15/18639	0.333333333333333	1.28314745972739	0.346159147269626	0.683385792383409
GO:0141050	histone H3K deacetylase activity	5/4842	15/18639	0.333333333333333	1.28314745972739	0.346159147269626	0.683385792383409
GO:0141051	histone H4K deacetylase activity	5/4842	15/18639	0.333333333333333	1.28314745972739	0.346159147269626	0.683385792383409
GO:0001046	core promoter sequence-specific DNA binding	13/4842	44/18639	0.295454545454545	1.13733524839473	0.347725878369027	0.683385792383409
GO:0016790	thiolester hydrolase activity	13/4842	44/18639	0.295454545454545	1.13733524839473	0.347725878369027	0.683385792383409
GO:0033192	calmodulin-dependent protein phosphatase activity	23/4842	81/18639	0.283950617283951	1.09305153976777	0.349252473541079	0.683385792383409
GO:0140791	histone H2AXS140 phosphatase activity	23/4842	81/18639	0.283950617283951	1.09305153976777	0.349252473541079	0.683385792383409
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	23/4842	81/18639	0.283950617283951	1.09305153976777	0.349252473541079	0.683385792383409
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	23/4842	81/18639	0.283950617283951	1.09305153976777	0.349252473541079	0.683385792383409
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	23/4842	81/18639	0.283950617283951	1.09305153976777	0.349252473541079	0.683385792383409
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	23/4842	81/18639	0.283950617283951	1.09305153976777	0.349252473541079	0.683385792383409
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	23/4842	81/18639	0.283950617283951	1.09305153976777	0.349252473541079	0.683385792383409
GO:1990439	MAP kinase serine/threonine phosphatase activity	23/4842	81/18639	0.283950617283951	1.09305153976777	0.349252473541079	0.683385792383409
GO:0004896	cytokine receptor activity	27/4842	96/18639	0.28125	1.08265566914498	0.351927796891036	0.687628375481622
GO:0008198	ferrous iron binding	8/4842	26/18639	0.307692307692308	1.18444380897913	0.357571736511183	0.696648383202821
GO:0052742	phosphatidylinositol kinase activity	8/4842	26/18639	0.307692307692308	1.18444380897913	0.357571736511183	0.696648383202821
GO:0101005	deubiquitinase activity	32/4842	115/18639	0.278260869565217	1.07114918377243	0.358906957237174	0.698110203531722
GO:0070001	aspartic-type peptidase activity	11/4842	37/18639	0.297297297297297	1.14442881543253	0.359620945241917	0.698110203531722
GO:0003684	damaged DNA binding	21/4842	74/18639	0.283783783783784	1.09240932382196	0.360381373504576	0.698110203531722
GO:0048029	monosaccharide binding	21/4842	74/18639	0.283783783783784	1.09240932382196	0.360381373504576	0.698110203531722
GO:0004843	cysteine-type deubiquitinase activity	30/4842	108/18639	0.277777777777778	1.06928954977282	0.369475528915744	0.711833146871754
GO:0008381	mechanosensitive monoatomic ion channel activity	6/4842	19/18639	0.315789473684211	1.21561338289963	0.369565291591235	0.711833146871754
GO:0022840	leak channel activity	6/4842	19/18639	0.315789473684211	1.21561338289963	0.369565291591235	0.711833146871754
GO:0022842	narrow pore channel activity	6/4842	19/18639	0.315789473684211	1.21561338289963	0.369565291591235	0.711833146871754
GO:0042287	MHC protein binding	12/4842	41/18639	0.292682926829268	1.12666606219966	0.371388161629976	0.712358757767929
GO:0016500	protein-hormone receptor activity	19/4842	67/18639	0.283582089552239	1.09163291349942	0.372430271853865	0.712358757767929
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	9/4842	30/18639	0.3	1.15483271375465	0.37281645881254	0.712358757767929
GO:0016769	transferase activity, transferring nitrogenous groups	9/4842	30/18639	0.3	1.15483271375465	0.37281645881254	0.712358757767929
GO:0022839	monoatomic ion-gated channel activity	9/4842	30/18639	0.3	1.15483271375465	0.37281645881254	0.712358757767929
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	23/4842	82/18639	0.280487804878049	1.07972164294134	0.374340439692552	0.712358757767929
GO:0033549	MAP kinase phosphatase activity	23/4842	82/18639	0.280487804878049	1.07972164294134	0.374340439692552	0.712358757767929
GO:0015294	solute:monoatomic cation symporter activity	32/4842	116/18639	0.275862068965517	1.06191513908473	0.380071769039995	0.712358757767929
GO:0016209	antioxidant activity	24/4842	86/18639	0.27906976744186	1.07426298953921	0.380779071194747	0.712358757767929
GO:0000995	RNA polymerase III general transcription initiation factor activity	4/4842	12/18639	0.333333333333333	1.28314745972739	0.381662286055658	0.712358757767929
GO:0004875	complement receptor activity	4/4842	12/18639	0.333333333333333	1.28314745972739	0.381662286055658	0.712358757767929
GO:0005049	nuclear export signal receptor activity	4/4842	12/18639	0.333333333333333	1.28314745972739	0.381662286055658	0.712358757767929
GO:0005527	macrolide binding	4/4842	12/18639	0.333333333333333	1.28314745972739	0.381662286055658	0.712358757767929
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	4/4842	12/18639	0.333333333333333	1.28314745972739	0.381662286055658	0.712358757767929
GO:0034452	dynactin binding	4/4842	12/18639	0.333333333333333	1.28314745972739	0.381662286055658	0.712358757767929
GO:0042301	phosphate ion binding	4/4842	12/18639	0.333333333333333	1.28314745972739	0.381662286055658	0.712358757767929
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	4/4842	12/18639	0.333333333333333	1.28314745972739	0.381662286055658	0.712358757767929
GO:0070410	co-SMAD binding	4/4842	12/18639	0.333333333333333	1.28314745972739	0.381662286055658	0.712358757767929
GO:0070679	inositol 1,4,5 trisphosphate binding	4/4842	12/18639	0.333333333333333	1.28314745972739	0.381662286055658	0.712358757767929
GO:0141221	histone deacetylase activity, hydrolytic mechanism	4/4842	12/18639	0.333333333333333	1.28314745972739	0.381662286055658	0.712358757767929
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/4842	12/18639	0.333333333333333	1.28314745972739	0.381662286055658	0.712358757767929
GO:1990459	transferrin receptor binding	4/4842	12/18639	0.333333333333333	1.28314745972739	0.381662286055658	0.712358757767929
GO:0008009	chemokine activity	13/4842	45/18639	0.288888888888889	1.11206113176373	0.381920956413927	0.712358757767929
GO:0001098	basal transcription machinery binding	17/4842	60/18639	0.283333333333333	1.09067534076828	0.385592018876239	0.716774615432702
GO:0001099	basal RNA polymerase II transcription machinery binding	17/4842	60/18639	0.283333333333333	1.09067534076828	0.385592018876239	0.716774615432702
GO:0016831	carboxy-lyase activity	10/4842	34/18639	0.294117647058824	1.13218893505358	0.385874239871587	0.716774615432702
GO:0005283	amino acid:sodium symporter activity	7/4842	23/18639	0.304347826086957	1.17156941975109	0.387757704020484	0.717325302389872
GO:0016849	phosphorus-oxygen lyase activity	7/4842	23/18639	0.304347826086957	1.17156941975109	0.387757704020484	0.717325302389872
GO:0043274	phospholipase binding	7/4842	23/18639	0.304347826086957	1.17156941975109	0.387757704020484	0.717325302389872
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	35/4842	128/18639	0.2734375	1.05258190055762	0.394608937072769	0.729005066308821
GO:0005109	frizzled binding	11/4842	38/18639	0.289473684210526	1.11431226765799	0.397273049720595	0.7329282386682
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	36/4842	132/18639	0.272727272727273	1.04984792159513	0.399139542413412	0.733909474532871
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	23/4842	83/18639	0.27710843373494	1.06671294844807	0.399723489464509	0.733909474532871
GO:0005246	calcium channel regulator activity	15/4842	53/18639	0.283018867924528	1.08946482429684	0.400133580911646	0.733909474532871
GO:0016860	intramolecular oxidoreductase activity	15/4842	53/18639	0.283018867924528	1.08946482429684	0.400133580911646	0.733909474532871
GO:0003777	microtubule motor activity	19/4842	68/18639	0.279411764705882	1.0755794883009	0.400511070172806	0.733909474532871
GO:0001671	ATPase activator activity	8/4842	27/18639	0.296296296296296	1.14057551975768	0.402557477055082	0.735671076666699
GO:0005044	scavenger receptor activity	8/4842	27/18639	0.296296296296296	1.14057551975768	0.402557477055082	0.735671076666699
GO:0000062	fatty-acyl-CoA binding	5/4842	16/18639	0.3125	1.20295074349442	0.405219230395672	0.736564713695083
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/4842	16/18639	0.3125	1.20295074349442	0.405219230395672	0.736564713695083
GO:0005159	insulin-like growth factor receptor binding	5/4842	16/18639	0.3125	1.20295074349442	0.405219230395672	0.736564713695083
GO:0015378	sodium:chloride symporter activity	5/4842	16/18639	0.3125	1.20295074349442	0.405219230395672	0.736564713695083
GO:0051082	unfolded protein binding	33/4842	121/18639	0.272727272727273	1.04984792159513	0.406170311171776	0.737305143171256
GO:0005452	solute:inorganic anion antiporter activity	9/4842	31/18639	0.290322580645161	1.11758004556901	0.414995084119425	0.749312029382077
GO:0008327	methyl-CpG binding	9/4842	31/18639	0.290322580645161	1.11758004556901	0.414995084119425	0.749312029382077
GO:0017147	Wnt-protein binding	9/4842	31/18639	0.290322580645161	1.11758004556901	0.414995084119425	0.749312029382077
GO:0070273	phosphatidylinositol-4-phosphate binding	9/4842	31/18639	0.290322580645161	1.11758004556901	0.414995084119425	0.749312029382077
GO:0016505	peptidase activator activity involved in apoptotic process	6/4842	20/18639	0.3	1.15483271375465	0.42258095248686	0.760982432366776
GO:0061608	nuclear import signal receptor activity	6/4842	20/18639	0.3	1.15483271375465	0.42258095248686	0.760982432366776
GO:0017018	myosin phosphatase activity	23/4842	84/18639	0.273809523809524	1.05401398477607	0.425291656396986	0.762556622818129
GO:0034061	DNA polymerase activity	10/4842	35/18639	0.285714285714286	1.09984067976633	0.425704545334309	0.762556622818129
GO:0043015	gamma-tubulin binding	10/4842	35/18639	0.285714285714286	1.09984067976633	0.425704545334309	0.762556622818129
GO:0061631	ubiquitin conjugating enzyme activity	10/4842	35/18639	0.285714285714286	1.09984067976633	0.425704545334309	0.762556622818129
GO:0004722	protein serine/threonine phosphatase activity	28/4842	103/18639	0.271844660194175	1.04645035550583	0.42675263762841	0.763425562828659
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	33/4842	122/18639	0.270491803278689	1.04124261076239	0.427391467630347	0.763561040983861
GO:0016651	oxidoreductase activity, acting on NAD(P)H	24/4842	88/18639	0.272727272727273	1.04984792159513	0.430687552679739	0.768437265044376
GO:0004521	RNA endonuclease activity	20/4842	73/18639	0.273972602739726	1.05464174772114	0.434805583977732	0.771269481452992
GO:0016298	lipase activity	35/4842	130/18639	0.269230769230769	1.03638833285673	0.435753718239741	0.771269481452992
GO:0004806	triacylglycerol lipase activity	7/4842	24/18639	0.291666666666667	1.12275402726146	0.436256410231891	0.771269481452992
GO:0005315	phosphate transmembrane transporter activity	7/4842	24/18639	0.291666666666667	1.12275402726146	0.436256410231891	0.771269481452992
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	7/4842	24/18639	0.291666666666667	1.12275402726146	0.436256410231891	0.771269481452992
GO:0030552	cAMP binding	7/4842	24/18639	0.291666666666667	1.12275402726146	0.436256410231891	0.771269481452992
GO:0060229	lipase activator activity	7/4842	24/18639	0.291666666666667	1.12275402726146	0.436256410231891	0.771269481452992
GO:0017116	single-stranded DNA helicase activity	16/4842	58/18639	0.275862068965517	1.06191513908473	0.439095314017744	0.775277663812579
GO:0008253	5'-nucleotidase activity	4/4842	13/18639	0.307692307692308	1.18444380897913	0.448533008011418	0.783776751112735
GO:0019104	DNA N-glycosylase activity	4/4842	13/18639	0.307692307692308	1.18444380897913	0.448533008011418	0.783776751112735
GO:0032396	inhibitory MHC class I receptor activity	4/4842	13/18639	0.307692307692308	1.18444380897913	0.448533008011418	0.783776751112735
GO:0039706	co-receptor binding	4/4842	13/18639	0.307692307692308	1.18444380897913	0.448533008011418	0.783776751112735
GO:0045159	myosin II binding	4/4842	13/18639	0.307692307692308	1.18444380897913	0.448533008011418	0.783776751112735
GO:0071714	icosanoid transmembrane transporter activity	4/4842	13/18639	0.307692307692308	1.18444380897913	0.448533008011418	0.783776751112735
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	4/4842	13/18639	0.307692307692308	1.18444380897913	0.448533008011418	0.783776751112735
GO:0140410	monoatomic cation:bicarbonate symporter activity	4/4842	13/18639	0.307692307692308	1.18444380897913	0.448533008011418	0.783776751112735
GO:0097110	scaffold protein binding	19/4842	70/18639	0.271428571428571	1.04484864577801	0.457098528900482	0.797716351594663
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	48/4842	181/18639	0.265193370165746	1.02084659779416	0.462129310266431	0.803036446687673
GO:0017110	nucleoside diphosphate phosphatase activity	5/4842	17/18639	0.294117647058824	1.13218893505358	0.463512903522141	0.803036446687673
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	5/4842	17/18639	0.294117647058824	1.13218893505358	0.463512903522141	0.803036446687673
GO:0070402	NADPH binding	5/4842	17/18639	0.294117647058824	1.13218893505358	0.463512903522141	0.803036446687673
GO:1901567	fatty acid derivative binding	5/4842	17/18639	0.294117647058824	1.13218893505358	0.463512903522141	0.803036446687673
GO:0140101	catalytic activity, acting on a tRNA	37/4842	139/18639	0.266187050359712	1.02467171244417	0.463700249082926	0.803036446687673
GO:0004869	cysteine-type endopeptidase inhibitor activity	10/4842	36/18639	0.277777777777778	1.06928954977282	0.465396182862924	0.8049454387272
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	16/4842	59/18639	0.271186440677966	1.04391657740533	0.470027391005696	0.810886949368605
GO:0045309	protein phosphorylated amino acid binding	16/4842	59/18639	0.271186440677966	1.04391657740533	0.470027391005696	0.810886949368605
GO:0009931	calcium-dependent protein serine/threonine kinase activity	6/4842	21/18639	0.285714285714286	1.09984067976633	0.474908492750346	0.814128844714878
GO:0019200	carbohydrate kinase activity	6/4842	21/18639	0.285714285714286	1.09984067976633	0.474908492750346	0.814128844714878
GO:0035613	RNA stem-loop binding	6/4842	21/18639	0.285714285714286	1.09984067976633	0.474908492750346	0.814128844714878
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	6/4842	21/18639	0.285714285714286	1.09984067976633	0.474908492750346	0.814128844714878
GO:0072542	protein phosphatase activator activity	6/4842	21/18639	0.285714285714286	1.09984067976633	0.474908492750346	0.814128844714878
GO:0050660	flavin adenine dinucleotide binding	23/4842	86/18639	0.267441860465116	1.02950203164174	0.476548438024045	0.815908689344199
GO:0019205	nucleobase-containing compound kinase activity	12/4842	44/18639	0.272727272727273	1.04984792159513	0.47937338897874	0.81971035996869
GO:0005525	GTP binding	99/4842	378/18639	0.261904761904762	1.0081872897858	0.48200775889842	0.820592703325898
GO:0001848	complement binding	7/4842	25/18639	0.28	1.077843866171	0.484125488687845	0.820592703325898
GO:0005537	D-mannose binding	7/4842	25/18639	0.28	1.077843866171	0.484125488687845	0.820592703325898
GO:0008483	transaminase activity	7/4842	25/18639	0.28	1.077843866171	0.484125488687845	0.820592703325898
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	7/4842	25/18639	0.28	1.077843866171	0.484125488687845	0.820592703325898
GO:0017025	TBP-class protein binding	7/4842	25/18639	0.28	1.077843866171	0.484125488687845	0.820592703325898
GO:0047617	fatty acyl-CoA hydrolase activity	7/4842	25/18639	0.28	1.077843866171	0.484125488687845	0.820592703325898
GO:0016410	N-acyltransferase activity	25/4842	94/18639	0.265957446808511	1.02378786680376	0.484903982075583	0.820886141940688
GO:0099604	ligand-gated calcium channel activity	8/4842	29/18639	0.275862068965517	1.06191513908473	0.491888620192957	0.82571687775545
GO:0046906	tetrapyrrole binding	40/4842	152/18639	0.263157894736842	1.01301115241636	0.493122519690579	0.82571687775545
GO:0019956	chemokine binding	9/4842	33/18639	0.272727272727273	1.04984792159513	0.49861672613848	0.82571687775545
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	16/4842	60/18639	0.266666666666667	1.02651796778191	0.500731162689134	0.82571687775545
GO:0008081	phosphoric diester hydrolase activity	23/4842	87/18639	0.264367816091954	1.0176686749562	0.502025971250454	0.82571687775545
GO:0004090	carbonyl reductase (NADPH) activity	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0005131	growth hormone receptor binding	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0005528	FK506 binding	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0031956	medium-chain fatty acid-CoA ligase activity	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0032052	bile acid binding	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0032356	oxidized DNA binding	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0035374	chondroitin sulfate binding	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0042975	peroxisome proliferator activated receptor binding	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0043121	neurotrophin binding	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0051880	G-quadruplex DNA binding	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0071723	lipopeptide binding	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	3/4842	10/18639	0.3	1.15483271375465	0.503589865710735	0.82571687775545
GO:0001530	lipopolysaccharide binding	11/4842	41/18639	0.268292682926829	1.03277722368302	0.509929603677414	0.8340947437715
GO:0017080	sodium channel regulator activity	11/4842	41/18639	0.268292682926829	1.03277722368302	0.509929603677414	0.8340947437715
GO:0005347	ATP transmembrane transporter activity	4/4842	14/18639	0.285714285714286	1.09984067976633	0.512884858576425	0.836575485006286
GO:1901474	azole transmembrane transporter activity	4/4842	14/18639	0.285714285714286	1.09984067976633	0.512884858576425	0.836575485006286
GO:0042379	chemokine receptor binding	19/4842	72/18639	0.263888888888889	1.01582507228418	0.513297052747219	0.836575485006286
GO:0061135	endopeptidase regulator activity	48/4842	184/18639	0.260869565217391	1.00420235978665	0.514851684910666	0.837682916043228
GO:0017022	myosin binding	20/4842	76/18639	0.263157894736842	1.01301115241636	0.517042230221473	0.837682916043228
GO:0004866	endopeptidase inhibitor activity	42/4842	161/18639	0.260869565217391	1.00420235978665	0.517658037009996	0.837682916043228
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	5/4842	18/18639	0.277777777777778	1.06928954977282	0.51994256417506	0.837682916043228
GO:0008308	voltage-gated monoatomic anion channel activity	5/4842	18/18639	0.277777777777778	1.06928954977282	0.51994256417506	0.837682916043228
GO:0008525	phosphatidylcholine transporter activity	5/4842	18/18639	0.277777777777778	1.06928954977282	0.51994256417506	0.837682916043228
GO:0015373	monoatomic anion:sodium symporter activity	5/4842	18/18639	0.277777777777778	1.06928954977282	0.51994256417506	0.837682916043228
GO:0050811	GABA receptor binding	5/4842	18/18639	0.277777777777778	1.06928954977282	0.51994256417506	0.837682916043228
GO:1990381	ubiquitin-specific protease binding	5/4842	18/18639	0.277777777777778	1.06928954977282	0.51994256417506	0.837682916043228
GO:0003924	GTPase activity	86/4842	331/18639	0.259818731117825	1.00015723447029	0.52063875003605	0.837682916043228
GO:0030414	peptidase inhibitor activity	44/4842	169/18639	0.260355029585799	1.0022216845208	0.522742929200179	0.837682916043228
GO:0008649	rRNA methyltransferase activity	6/4842	22/18639	0.272727272727273	1.04984792159513	0.525748880272294	0.837682916043228
GO:0016881	acid-amino acid ligase activity	6/4842	22/18639	0.272727272727273	1.04984792159513	0.525748880272294	0.837682916043228
GO:0030021	extracellular matrix structural constituent conferring compression resistance	6/4842	22/18639	0.272727272727273	1.04984792159513	0.525748880272294	0.837682916043228
GO:0033691	sialic acid binding	6/4842	22/18639	0.272727272727273	1.04984792159513	0.525748880272294	0.837682916043228
GO:0034062	5'-3' RNA polymerase activity	6/4842	22/18639	0.272727272727273	1.04984792159513	0.525748880272294	0.837682916043228
GO:0061133	endopeptidase activator activity	6/4842	22/18639	0.272727272727273	1.04984792159513	0.525748880272294	0.837682916043228
GO:0070034	telomerase RNA binding	6/4842	22/18639	0.272727272727273	1.04984792159513	0.525748880272294	0.837682916043228
GO:0097747	RNA polymerase activity	6/4842	22/18639	0.272727272727273	1.04984792159513	0.525748880272294	0.837682916043228
GO:0015293	symporter activity	38/4842	146/18639	0.26027397260274	1.00190966033508	0.526331743708577	0.837682916043228
GO:0004601	peroxidase activity	15/4842	57/18639	0.263157894736842	1.01301115241636	0.527371046314039	0.838353034937674
GO:0016289	acyl-CoA hydrolase activity	7/4842	26/18639	0.269230769230769	1.03638833285673	0.530750555279248	0.841751757846386
GO:0120014	phospholipid transfer activity	7/4842	26/18639	0.269230769230769	1.03638833285673	0.530750555279248	0.841751757846386
GO:0008106	alcohol dehydrogenase (NADP+) activity	8/4842	30/18639	0.266666666666667	1.02651796778191	0.535187587967653	0.847797160378665
GO:0090482	vitamin transmembrane transporter activity	9/4842	34/18639	0.264705882352941	1.01897004154822	0.539204021194562	0.85316295535569
GO:0015085	calcium ion transmembrane transporter activity	38/4842	147/18639	0.258503401360544	0.995093948360013	0.545777886697458	0.860310381861703
GO:0016859	cis-trans isomerase activity	11/4842	42/18639	0.261904761904762	1.0081872897858	0.546319746841156	0.860310381861703
GO:0042056	chemoattractant activity	11/4842	42/18639	0.261904761904762	1.0081872897858	0.546319746841156	0.860310381861703
GO:0051879	Hsp90 protein binding	11/4842	42/18639	0.261904761904762	1.0081872897858	0.546319746841156	0.860310381861703
GO:0005126	cytokine receptor binding	71/4842	275/18639	0.258181818181818	0.993856032443393	0.547527920019653	0.860310381861703
GO:1901681	sulfur compound binding	71/4842	275/18639	0.258181818181818	0.993856032443393	0.547527920019653	0.860310381861703
GO:0032813	tumor necrosis factor receptor superfamily binding	13/4842	50/18639	0.26	1.00085501858736	0.552556968745661	0.861125699371373
GO:0004620	phospholipase activity	28/4842	109/18639	0.256880733944954	0.988847583643123	0.564208833405338	0.861125699371373
GO:0004089	carbonate dehydratase activity	4/4842	15/18639	0.266666666666667	1.02651796778191	0.573512389960715	0.861125699371373
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/4842	15/18639	0.266666666666667	1.02651796778191	0.573512389960715	0.861125699371373
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/4842	15/18639	0.266666666666667	1.02651796778191	0.573512389960715	0.861125699371373
GO:0004865	protein serine/threonine phosphatase inhibitor activity	4/4842	15/18639	0.266666666666667	1.02651796778191	0.573512389960715	0.861125699371373
GO:0031005	filamin binding	4/4842	15/18639	0.266666666666667	1.02651796778191	0.573512389960715	0.861125699371373
GO:0050700	CARD domain binding	4/4842	15/18639	0.266666666666667	1.02651796778191	0.573512389960715	0.861125699371373
GO:0050780	dopamine receptor binding	4/4842	15/18639	0.266666666666667	1.02651796778191	0.573512389960715	0.861125699371373
GO:0008574	plus-end-directed microtubule motor activity	5/4842	19/18639	0.263157894736842	1.01301115241636	0.573648732954997	0.861125699371373
GO:0015245	fatty acid transmembrane transporter activity	5/4842	19/18639	0.263157894736842	1.01301115241636	0.573648732954997	0.861125699371373
GO:0030506	ankyrin binding	5/4842	19/18639	0.263157894736842	1.01301115241636	0.573648732954997	0.861125699371373
GO:0042577	lipid phosphatase activity	5/4842	19/18639	0.263157894736842	1.01301115241636	0.573648732954997	0.861125699371373
GO:0046624	sphingolipid transporter activity	5/4842	19/18639	0.263157894736842	1.01301115241636	0.573648732954997	0.861125699371373
GO:0050145	nucleoside monophosphate kinase activity	5/4842	19/18639	0.263157894736842	1.01301115241636	0.573648732954997	0.861125699371373
GO:0070003	threonine-type peptidase activity	5/4842	19/18639	0.263157894736842	1.01301115241636	0.573648732954997	0.861125699371373
GO:0120227	acyl-CoA binding	5/4842	19/18639	0.263157894736842	1.01301115241636	0.573648732954997	0.861125699371373
GO:1990380	K48-linked deubiquitinase activity	5/4842	19/18639	0.263157894736842	1.01301115241636	0.573648732954997	0.861125699371373
GO:0031681	G-protein beta-subunit binding	6/4842	23/18639	0.260869565217391	1.00420235978665	0.574451648361169	0.861125699371373
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	6/4842	23/18639	0.260869565217391	1.00420235978665	0.574451648361169	0.861125699371373
GO:0140102	catalytic activity, acting on a rRNA	6/4842	23/18639	0.260869565217391	1.00420235978665	0.574451648361169	0.861125699371373
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	22/4842	86/18639	0.255813953488372	0.984741073744272	0.57461579776462	0.861125699371373
GO:0000099	sulfur amino acid transmembrane transporter activity	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0003953	NAD+ nucleosidase activity	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0004016	adenylate cyclase activity	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0005114	type II transforming growth factor beta receptor binding	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0005225	volume-sensitive anion channel activity	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0008172	S-methyltransferase activity	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0008526	phosphatidylinositol transfer activity	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0015217	ADP transmembrane transporter activity	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0019107	myristoyltransferase activity	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0034056	estrogen response element binding	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0043522	leucine zipper domain binding	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0045294	alpha-catenin binding	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0048407	platelet-derived growth factor binding	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0050786	RAGE receptor binding	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0070990	snRNP binding	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0140031	phosphorylation-dependent protein binding	3/4842	11/18639	0.272727272727273	1.04984792159513	0.574718848031779	0.861125699371373
GO:0004683	calcium/calmodulin-dependent protein kinase activity	7/4842	27/18639	0.259259259259259	0.998003579787966	0.575618132657705	0.861521178679744
GO:0072349	modified amino acid transmembrane transporter activity	8/4842	31/18639	0.258064516129032	0.993404484950234	0.576993676262689	0.862627811479831
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	10/4842	39/18639	0.256410256410256	0.987036507482604	0.580063096790284	0.866261629127341
GO:0031593	polyubiquitin modification-dependent protein binding	15/4842	59/18639	0.254237288135593	0.978671791317497	0.588211786671387	0.877464447443784
GO:0005507	copper ion binding	16/4842	63/18639	0.253968253968254	0.977636159792294	0.589829358455586	0.87891056051184
GO:0020037	heme binding	36/4842	142/18639	0.253521126760563	0.975914969370124	0.59963114406592	0.89253548995981
GO:0019001	guanyl nucleotide binding	102/4842	400/18639	0.255	0.98160780669145	0.606299396553584	0.900484098276737
GO:0032561	guanyl ribonucleotide binding	102/4842	400/18639	0.255	0.98160780669145	0.606299396553584	0.900484098276737
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	10/4842	40/18639	0.25	0.962360594795539	0.615830812889061	0.907108692352013
GO:0071949	FAD binding	10/4842	40/18639	0.25	0.962360594795539	0.615830812889061	0.907108692352013
GO:0016879	ligase activity, forming carbon-nitrogen bonds	12/4842	48/18639	0.25	0.962360594795539	0.615947787598881	0.907108692352013
GO:0038187	pattern recognition receptor activity	12/4842	48/18639	0.25	0.962360594795539	0.615947787598881	0.907108692352013
GO:0004033	aldo-keto reductase (NADPH) activity	9/4842	36/18639	0.25	0.962360594795539	0.616191007445737	0.907108692352013
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	9/4842	36/18639	0.25	0.962360594795539	0.616191007445737	0.907108692352013
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	9/4842	36/18639	0.25	0.962360594795539	0.616191007445737	0.907108692352013
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	9/4842	36/18639	0.25	0.962360594795539	0.616191007445737	0.907108692352013
GO:0170055	lipid transmembrane transporter activity	14/4842	56/18639	0.25	0.962360594795539	0.616780394062357	0.907108692352013
GO:0046625	sphingolipid binding	7/4842	28/18639	0.25	0.962360594795539	0.618319197423042	0.908099512839916
GO:1990841	promoter-specific chromatin binding	17/4842	68/18639	0.25	0.962360594795539	0.618793473351093	0.908099512839916
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	6/4842	24/18639	0.25	0.962360594795539	0.620516727737595	0.908661644505593
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	6/4842	24/18639	0.25	0.962360594795539	0.620516727737595	0.908661644505593
GO:0048306	calcium-dependent protein binding	20/4842	80/18639	0.25	0.962360594795539	0.621316270123983	0.908850984129581
GO:0000339	RNA cap binding	5/4842	20/18639	0.25	0.962360594795539	0.624004659777709	0.910182632100351
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	5/4842	20/18639	0.25	0.962360594795539	0.624004659777709	0.910182632100351
GO:0016874	ligase activity	42/4842	167/18639	0.251497005988024	0.968123233087728	0.625944106592841	0.910182632100351
GO:0008514	organic anion transmembrane transporter activity	68/4842	269/18639	0.252788104089219	0.973093240834151	0.626856494569731	0.910182632100351
GO:0043022	ribosome binding	28/4842	112/18639	0.25	0.962360594795539	0.629031758242216	0.910182632100351
GO:0005324	long-chain fatty acid transmembrane transporter activity	4/4842	16/18639	0.25	0.962360594795539	0.629610109815729	0.910182632100351
GO:0008296	3'-5'-DNA exonuclease activity	4/4842	16/18639	0.25	0.962360594795539	0.629610109815729	0.910182632100351
GO:0017070	U6 snRNA binding	4/4842	16/18639	0.25	0.962360594795539	0.629610109815729	0.910182632100351
GO:0022858	alanine transmembrane transporter activity	4/4842	16/18639	0.25	0.962360594795539	0.629610109815729	0.910182632100351
GO:0030275	LRR domain binding	4/4842	16/18639	0.25	0.962360594795539	0.629610109815729	0.910182632100351
GO:0043023	ribosomal large subunit binding	4/4842	16/18639	0.25	0.962360594795539	0.629610109815729	0.910182632100351
GO:0003995	acyl-CoA dehydrogenase activity	3/4842	12/18639	0.25	0.962360594795539	0.639071035357153	0.910273449521323
GO:0004000	adenosine deaminase activity	3/4842	12/18639	0.25	0.962360594795539	0.639071035357153	0.910273449521323
GO:0004126	cytidine deaminase activity	3/4842	12/18639	0.25	0.962360594795539	0.639071035357153	0.910273449521323
GO:0004300	enoyl-CoA hydratase activity	3/4842	12/18639	0.25	0.962360594795539	0.639071035357153	0.910273449521323
GO:0005436	sodium:phosphate symporter activity	3/4842	12/18639	0.25	0.962360594795539	0.639071035357153	0.910273449521323
GO:0008179	adenylate cyclase binding	3/4842	12/18639	0.25	0.962360594795539	0.639071035357153	0.910273449521323
GO:0015132	prostaglandin transmembrane transporter activity	3/4842	12/18639	0.25	0.962360594795539	0.639071035357153	0.910273449521323
GO:0043047	single-stranded telomeric DNA binding	3/4842	12/18639	0.25	0.962360594795539	0.639071035357153	0.910273449521323
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	3/4842	12/18639	0.25	0.962360594795539	0.639071035357153	0.910273449521323
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	3/4842	12/18639	0.25	0.962360594795539	0.639071035357153	0.910273449521323
GO:0097371	MDM2/MDM4 family protein binding	3/4842	12/18639	0.25	0.962360594795539	0.639071035357153	0.910273449521323
GO:0140829	bicarbonate:monoatomic anion antiporter activity	3/4842	12/18639	0.25	0.962360594795539	0.639071035357153	0.910273449521323
GO:0140900	chloride:bicarbonate antiporter activity	3/4842	12/18639	0.25	0.962360594795539	0.639071035357153	0.910273449521323
GO:1990817	poly(A) RNA polymerase activity	3/4842	12/18639	0.25	0.962360594795539	0.639071035357153	0.910273449521323
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	15/4842	61/18639	0.245901639344262	0.94658419160217	0.64552518166725	0.918501727534933
GO:0140296	general transcription initiation factor binding	13/4842	53/18639	0.245283018867925	0.944202847723925	0.646463300420803	0.918872364120136
GO:0051539	4 iron, 4 sulfur cluster binding	11/4842	45/18639	0.244444444444444	0.940974803800083	0.648439789554555	0.920716601713064
GO:0061650	ubiquitin-like protein conjugating enzyme activity	10/4842	41/18639	0.24390243902439	0.93888838516638	0.649992493279915	0.921955879589503
GO:0004181	metallocarboxypeptidase activity	7/4842	29/18639	0.241379310344828	0.929175746699141	0.658547108359887	0.930780530032413
GO:0005416	amino acid:monoatomic cation symporter activity	7/4842	29/18639	0.241379310344828	0.929175746699141	0.658547108359887	0.930780530032413
GO:0106222	lncRNA binding	7/4842	29/18639	0.241379310344828	0.929175746699141	0.658547108359887	0.930780530032413
GO:0015103	inorganic anion transmembrane transporter activity	41/4842	165/18639	0.248484848484848	0.956528106342233	0.658959667279584	0.930780530032413
GO:0043021	ribonucleoprotein complex binding	44/4842	177/18639	0.248587570621469	0.95692352928822	0.6612675240093	0.933068431380448
GO:0015271	outward rectifier potassium channel activity	6/4842	25/18639	0.24	0.923866171003717	0.663587645332253	0.933428264595991
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	6/4842	25/18639	0.24	0.923866171003717	0.663587645332253	0.933428264595991
GO:0019211	phosphatase activator activity	6/4842	25/18639	0.24	0.923866171003717	0.663587645332253	0.933428264595991
GO:0004222	metalloendopeptidase activity	27/4842	110/18639	0.245454545454545	0.94486312943562	0.669473947952865	0.937733538728576
GO:0003678	DNA helicase activity	18/4842	74/18639	0.243243243243243	0.936350848990254	0.670187007106894	0.937733538728576
GO:0031491	nucleosome binding	18/4842	74/18639	0.243243243243243	0.936350848990254	0.670187007106894	0.937733538728576
GO:0010314	phosphatidylinositol-5-phosphate binding	5/4842	21/18639	0.238095238095238	0.916533899805275	0.670597211973761	0.937733538728576
GO:0036122	BMP binding	5/4842	21/18639	0.238095238095238	0.916533899805275	0.670597211973761	0.937733538728576
GO:0008028	monocarboxylic acid transmembrane transporter activity	17/4842	70/18639	0.242857142857143	0.934864577801381	0.670797590388436	0.937733538728576
GO:0005506	iron ion binding	38/4842	154/18639	0.246753246753247	0.94986240525274	0.673880524064953	0.940929841038821
GO:0048020	CCR chemokine receptor binding	12/4842	50/18639	0.24	0.923866171003717	0.677208235257468	0.940929841038821
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	11/4842	46/18639	0.239130434782609	0.920518829804429	0.679525882249304	0.940929841038821
GO:0004029	aldehyde dehydrogenase (NAD+) activity	4/4842	17/18639	0.235294117647059	0.90575114804286	0.680716942521448	0.940929841038821
GO:0004550	nucleoside diphosphate kinase activity	4/4842	17/18639	0.235294117647059	0.90575114804286	0.680716942521448	0.940929841038821
GO:0005092	GDP-dissociation inhibitor activity	4/4842	17/18639	0.235294117647059	0.90575114804286	0.680716942521448	0.940929841038821
GO:0008569	minus-end-directed microtubule motor activity	4/4842	17/18639	0.235294117647059	0.90575114804286	0.680716942521448	0.940929841038821
GO:0016018	cyclosporin A binding	4/4842	17/18639	0.235294117647059	0.90575114804286	0.680716942521448	0.940929841038821
GO:0036041	long-chain fatty acid binding	4/4842	17/18639	0.235294117647059	0.90575114804286	0.680716942521448	0.940929841038821
GO:0038191	neuropilin binding	4/4842	17/18639	0.235294117647059	0.90575114804286	0.680716942521448	0.940929841038821
GO:0045236	CXCR chemokine receptor binding	4/4842	17/18639	0.235294117647059	0.90575114804286	0.680716942521448	0.940929841038821
GO:0043531	ADP binding	9/4842	38/18639	0.236842105263158	0.911710037174721	0.685950428983578	0.946931989436855
GO:0015020	glucuronosyltransferase activity	8/4842	34/18639	0.235294117647059	0.90575114804286	0.690415947417629	0.946931989436855
GO:0072341	modified amino acid binding	22/4842	91/18639	0.241758241758242	0.930634421340741	0.690833261453574	0.946931989436855
GO:0033293	monocarboxylic acid binding	19/4842	79/18639	0.240506329113924	0.925815255752671	0.693026924371582	0.946931989436855
GO:0044183	protein folding chaperone	18/4842	75/18639	0.24	0.923866171003717	0.694060339304642	0.946931989436855
GO:0140299	molecular sensor activity	17/4842	71/18639	0.23943661971831	0.921697471071784	0.695283437101998	0.946931989436855
GO:0031210	phosphatidylcholine binding	7/4842	30/18639	0.233333333333333	0.89820322180917	0.696091310218393	0.946931989436855
GO:0098918	structural constituent of synapse	7/4842	30/18639	0.233333333333333	0.89820322180917	0.696091310218393	0.946931989436855
GO:0002161	aminoacyl-tRNA editing activity	3/4842	13/18639	0.230769230769231	0.888332856734344	0.696232443560873	0.946931989436855
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	3/4842	13/18639	0.230769230769231	0.888332856734344	0.696232443560873	0.946931989436855
GO:0004465	lipoprotein lipase activity	3/4842	13/18639	0.230769230769231	0.888332856734344	0.696232443560873	0.946931989436855
GO:0009982	pseudouridine synthase activity	3/4842	13/18639	0.230769230769231	0.888332856734344	0.696232443560873	0.946931989436855
GO:0031432	titin binding	3/4842	13/18639	0.230769230769231	0.888332856734344	0.696232443560873	0.946931989436855
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	3/4842	13/18639	0.230769230769231	0.888332856734344	0.696232443560873	0.946931989436855
GO:0071837	HMG box domain binding	3/4842	13/18639	0.230769230769231	0.888332856734344	0.696232443560873	0.946931989436855
GO:0089720	caspase binding	3/4842	13/18639	0.230769230769231	0.888332856734344	0.696232443560873	0.946931989436855
GO:0001786	phosphatidylserine binding	14/4842	59/18639	0.23728813559322	0.913427005229664	0.700431476922025	0.950735818524791
GO:0036002	pre-mRNA binding	14/4842	59/18639	0.23728813559322	0.913427005229664	0.700431476922025	0.950735818524791
GO:0004112	cyclic-nucleotide phosphodiesterase activity	6/4842	26/18639	0.230769230769231	0.888332856734344	0.703438772348155	0.951959057189718
GO:0004529	DNA exonuclease activity	6/4842	26/18639	0.230769230769231	0.888332856734344	0.703438772348155	0.951959057189718
GO:0051139	metal cation:proton antiporter activity	6/4842	26/18639	0.230769230769231	0.888332856734344	0.703438772348155	0.951959057189718
GO:0043495	protein-membrane adaptor activity	11/4842	47/18639	0.234042553191489	0.900933322787313	0.708926303483994	0.958428781180753
GO:0008970	phospholipase A1 activity	5/4842	22/18639	0.227272727272727	0.874873267995944	0.713199662474191	0.962287305786073
GO:0140517	protein-RNA adaptor activity	5/4842	22/18639	0.227272727272727	0.874873267995944	0.713199662474191	0.962287305786073
GO:0000049	tRNA binding	19/4842	80/18639	0.2375	0.914242565055762	0.715363029792965	0.964246787673221
GO:0000217	DNA secondary structure binding	9/4842	39/18639	0.230769230769231	0.888332856734344	0.717716628641566	0.965499750434487
GO:0016776	phosphotransferase activity, phosphate group as acceptor	9/4842	39/18639	0.230769230769231	0.888332856734344	0.717716628641566	0.965499750434487
GO:0005343	organic acid:sodium symporter activity	8/4842	35/18639	0.228571428571429	0.879872543813064	0.72357850923025	0.970779075649401
GO:0005372	water transmembrane transporter activity	4/4842	18/18639	0.222222222222222	0.855431639818257	0.726652479191845	0.970779075649401
GO:0015280	ligand-gated sodium channel activity	4/4842	18/18639	0.222222222222222	0.855431639818257	0.726652479191845	0.970779075649401
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	4/4842	18/18639	0.222222222222222	0.855431639818257	0.726652479191845	0.970779075649401
GO:0031690	adrenergic receptor binding	4/4842	18/18639	0.222222222222222	0.855431639818257	0.726652479191845	0.970779075649401
GO:0070628	proteasome binding	4/4842	18/18639	0.222222222222222	0.855431639818257	0.726652479191845	0.970779075649401
GO:1901611	phosphatidylglycerol binding	4/4842	18/18639	0.222222222222222	0.855431639818257	0.726652479191845	0.970779075649401
GO:0005164	tumor necrosis factor receptor binding	7/4842	31/18639	0.225806451612903	0.869228924331455	0.73082812012214	0.975396585517344
GO:0035255	ionotropic glutamate receptor binding	6/4842	27/18639	0.222222222222222	0.855431639818257	0.739958955116855	0.984775406659157
GO:0022853	active monoatomic ion transmembrane transporter activity	28/4842	118/18639	0.23728813559322	0.913427005229664	0.743617272518287	0.984775406659157
GO:0004705	JUN kinase activity	3/4842	14/18639	0.214285714285714	0.824880509824748	0.746236330374814	0.984775406659157
GO:0008195	phosphatidate phosphatase activity	3/4842	14/18639	0.214285714285714	0.824880509824748	0.746236330374814	0.984775406659157
GO:0008494	translation activator activity	3/4842	14/18639	0.214285714285714	0.824880509824748	0.746236330374814	0.984775406659157
GO:0015386	potassium:proton antiporter activity	3/4842	14/18639	0.214285714285714	0.824880509824748	0.746236330374814	0.984775406659157
GO:0016530	metallochaperone activity	3/4842	14/18639	0.214285714285714	0.824880509824748	0.746236330374814	0.984775406659157
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	3/4842	14/18639	0.214285714285714	0.824880509824748	0.746236330374814	0.984775406659157
GO:0098847	sequence-specific single stranded DNA binding	3/4842	14/18639	0.214285714285714	0.824880509824748	0.746236330374814	0.984775406659157
GO:1901612	cardiolipin binding	3/4842	14/18639	0.214285714285714	0.824880509824748	0.746236330374814	0.984775406659157
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	9/4842	40/18639	0.225	0.866124535315985	0.747296381601971	0.984775406659157
GO:0050997	quaternary ammonium group binding	9/4842	40/18639	0.225	0.866124535315985	0.747296381601971	0.984775406659157
GO:0140662	ATP-dependent protein folding chaperone	9/4842	40/18639	0.225	0.866124535315985	0.747296381601971	0.984775406659157
GO:0005484	SNAP receptor activity	8/4842	36/18639	0.222222222222222	0.855431639818257	0.754260652597254	0.992987810603763
GO:0005262	calcium channel activity	31/4842	131/18639	0.236641221374046	0.910936746218678	0.757352149745021	0.993500644344454
GO:0017046	peptide hormone binding	12/4842	53/18639	0.226415094339623	0.871571859437469	0.757535546106445	0.993500644344454
GO:0015106	bicarbonate transmembrane transporter activity	7/4842	32/18639	0.21875	0.842065520446097	0.762709746448308	0.993500644344454
GO:0016782	transferase activity, transferring sulphur-containing groups	16/4842	70/18639	0.228571428571429	0.879872543813064	0.765011781773461	0.993500644344454
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	4/4842	19/18639	0.210526315789474	0.810408921933085	0.767453478188338	0.993500644344454
GO:0016918	retinal binding	4/4842	19/18639	0.210526315789474	0.810408921933085	0.767453478188338	0.993500644344454
GO:0031420	alkali metal ion binding	4/4842	19/18639	0.210526315789474	0.810408921933085	0.767453478188338	0.993500644344454
GO:0016866	intramolecular transferase activity	6/4842	28/18639	0.214285714285714	0.824880509824748	0.773133434487895	0.993500644344454
GO:0046875	ephrin receptor binding	6/4842	28/18639	0.214285714285714	0.824880509824748	0.773133434487895	0.993500644344454
GO:0140828	metal cation:monoatomic cation antiporter activity	9/4842	41/18639	0.219512195121951	0.844999546649742	0.774663100192549	0.993500644344454
GO:0000182	rDNA binding	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0005345	purine nucleobase transmembrane transporter activity	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0008190	eukaryotic initiation factor 4E binding	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0015187	glycine transmembrane transporter activity	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0015203	polyamine transmembrane transporter activity	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0015643	toxic substance binding	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0016427	tRNA (cytidine) methyltransferase activity	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0016783	sulfurtransferase activity	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0016868	intramolecular phosphotransferase activity	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0030957	Tat protein binding	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0035256	G protein-coupled glutamate receptor binding	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0043208	glycosphingolipid binding	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0050815	phosphoserine residue binding	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0098505	G-rich strand telomeric DNA binding	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0140135	mechanosensitive monoatomic cation channel activity	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0141109	transporter activator activity	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:1990757	ubiquitin ligase activator activity	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:1990763	arrestin family protein binding	2/4842	10/18639	0.2	0.769888475836431	0.777362967293116	0.993500644344454
GO:0030551	cyclic nucleotide binding	8/4842	37/18639	0.216216216216216	0.832311865769115	0.782451596128293	0.999062489971719
GO:0005539	glycosaminoglycan binding	58/4842	242/18639	0.239669421487603	0.922593628068451	0.784488746407122	1
GO:0005540	hyaluronic acid binding	5/4842	24/18639	0.208333333333333	0.801967162329616	0.786273422181373	1
GO:0030215	semaphorin receptor binding	5/4842	24/18639	0.208333333333333	0.801967162329616	0.786273422181373	1
GO:0140612	DNA damage sensor activity	5/4842	24/18639	0.208333333333333	0.801967162329616	0.786273422181373	1
GO:0046873	metal ion transmembrane transporter activity	110/4842	450/18639	0.244444444444444	0.940974803800083	0.788824385640784	1
GO:0008242	omega peptidase activity	3/4842	15/18639	0.2	0.769888475836431	0.789417315478339	1
GO:0017081	chloride channel regulator activity	3/4842	15/18639	0.2	0.769888475836431	0.789417315478339	1
GO:0140161	monocarboxylate:sodium symporter activity	3/4842	15/18639	0.2	0.769888475836431	0.789417315478339	1
GO:0015108	chloride transmembrane transporter activity	28/4842	121/18639	0.231404958677686	0.89078005468678	0.791744110539952	1
GO:0070888	E-box binding	13/4842	59/18639	0.220338983050847	0.848182219141831	0.797694536717351	1
GO:0003785	actin monomer binding	6/4842	29/18639	0.206896551724138	0.79643635431355	0.803025519564766	1
GO:0001614	purinergic nucleotide receptor activity	4/4842	20/18639	0.2	0.769888475836431	0.803315682790995	1
GO:0016502	nucleotide receptor activity	4/4842	20/18639	0.2	0.769888475836431	0.803315682790995	1
GO:0140664	ATP-dependent DNA damage sensor activity	4/4842	20/18639	0.2	0.769888475836431	0.803315682790995	1
GO:0140223	general transcription initiation factor activity	15/4842	68/18639	0.220588235294118	0.849141701290181	0.808313307730535	1
GO:0003727	single-stranded RNA binding	20/4842	89/18639	0.224719101123595	0.865043231276889	0.808603209415953	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	2/4842	11/18639	0.181818181818182	0.699898614396756	0.822394993795635	1
GO:0004143	ATP-dependent diacylglycerol kinase activity	2/4842	11/18639	0.181818181818182	0.699898614396756	0.822394993795635	1
GO:0005536	D-glucose binding	2/4842	11/18639	0.181818181818182	0.699898614396756	0.822394993795635	1
GO:0008046	axon guidance receptor activity	2/4842	11/18639	0.181818181818182	0.699898614396756	0.822394993795635	1
GO:0008271	secondary active sulfate transmembrane transporter activity	2/4842	11/18639	0.181818181818182	0.699898614396756	0.822394993795635	1
GO:0008503	benzodiazepine receptor activity	2/4842	11/18639	0.181818181818182	0.699898614396756	0.822394993795635	1
GO:0010854	adenylate cyclase regulator activity	2/4842	11/18639	0.181818181818182	0.699898614396756	0.822394993795635	1
GO:0015173	aromatic amino acid transmembrane transporter activity	2/4842	11/18639	0.181818181818182	0.699898614396756	0.822394993795635	1
GO:0015205	nucleobase transmembrane transporter activity	2/4842	11/18639	0.181818181818182	0.699898614396756	0.822394993795635	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/4842	11/18639	0.181818181818182	0.699898614396756	0.822394993795635	1
GO:0034713	type I transforming growth factor beta receptor binding	2/4842	11/18639	0.181818181818182	0.699898614396756	0.822394993795635	1
GO:0035252	UDP-xylosyltransferase activity	2/4842	11/18639	0.181818181818182	0.699898614396756	0.822394993795635	1
GO:0042285	xylosyltransferase activity	2/4842	11/18639	0.181818181818182	0.699898614396756	0.822394993795635	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	2/4842	11/18639	0.181818181818182	0.699898614396756	0.822394993795635	1
GO:0050998	nitric-oxide synthase binding	2/4842	11/18639	0.181818181818182	0.699898614396756	0.822394993795635	1
GO:0070697	activin receptor binding	2/4842	11/18639	0.181818181818182	0.699898614396756	0.822394993795635	1
GO:0004707	MAP kinase activity	3/4842	16/18639	0.1875	0.721770446096654	0.82629590140048	1
GO:0005149	interleukin-1 receptor binding	3/4842	16/18639	0.1875	0.721770446096654	0.82629590140048	1
GO:0019841	retinol binding	3/4842	16/18639	0.1875	0.721770446096654	0.82629590140048	1
GO:0097027	ubiquitin-protein transferase activator activity	3/4842	16/18639	0.1875	0.721770446096654	0.82629590140048	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	11/4842	52/18639	0.211538461538462	0.814305118673148	0.829144290496335	1
GO:0035925	mRNA 3'-UTR AU-rich region binding	6/4842	30/18639	0.2	0.769888475836431	0.829759071901359	1
GO:0017171	serine hydrolase activity	46/4842	198/18639	0.232323232323232	0.894314896173632	0.833103354070977	1
GO:0008373	sialyltransferase activity	4/4842	21/18639	0.19047619047619	0.73322711984422	0.834543558277403	1
GO:0009975	cyclase activity	4/4842	21/18639	0.19047619047619	0.73322711984422	0.834543558277403	1
GO:0015125	bile acid transmembrane transporter activity	4/4842	21/18639	0.19047619047619	0.73322711984422	0.834543558277403	1
GO:0061891	calcium ion sensor activity	4/4842	21/18639	0.19047619047619	0.73322711984422	0.834543558277403	1
GO:0030247	polysaccharide binding	5/4842	26/18639	0.192307692307692	0.740277380611953	0.843970126880677	1
GO:0003697	single-stranded DNA binding	27/4842	121/18639	0.223140495867769	0.858966481305109	0.847874607427544	1
GO:0016835	carbon-oxygen lyase activity	17/4842	79/18639	0.215189873417722	0.828361018305021	0.849990259269194	1
GO:0015144	carbohydrate transmembrane transporter activity	8/4842	40/18639	0.2	0.769888475836431	0.852590878719505	1
GO:0035254	glutamate receptor binding	10/4842	49/18639	0.204081632653061	0.785600485547379	0.854868484905644	1
GO:0004659	prenyltransferase activity	3/4842	17/18639	0.176470588235294	0.679313361032145	0.857491392588844	1
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	3/4842	17/18639	0.176470588235294	0.679313361032145	0.857491392588844	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	3/4842	17/18639	0.176470588235294	0.679313361032145	0.857491392588844	1
GO:0031489	myosin V binding	3/4842	17/18639	0.176470588235294	0.679313361032145	0.857491392588844	1
GO:0070492	oligosaccharide binding	3/4842	17/18639	0.176470588235294	0.679313361032145	0.857491392588844	1
GO:0000340	RNA 7-methylguanosine cap binding	2/4842	12/18639	0.166666666666667	0.641573729863693	0.859059785483332	1
GO:0005165	neurotrophin receptor binding	2/4842	12/18639	0.166666666666667	0.641573729863693	0.859059785483332	1
GO:0015166	polyol transmembrane transporter activity	2/4842	12/18639	0.166666666666667	0.641573729863693	0.859059785483332	1
GO:0015269	calcium-activated potassium channel activity	2/4842	12/18639	0.166666666666667	0.641573729863693	0.859059785483332	1
GO:0015368	calcium:monoatomic cation antiporter activity	2/4842	12/18639	0.166666666666667	0.641573729863693	0.859059785483332	1
GO:0008201	heparin binding	39/4842	172/18639	0.226744186046512	0.872838679000605	0.860518129316503	1
GO:0031683	G-protein beta/gamma-subunit complex binding	4/4842	22/18639	0.181818181818182	0.699898614396756	0.861508868455895	1
GO:0140784	metal ion sensor activity	4/4842	22/18639	0.181818181818182	0.699898614396756	0.861508868455895	1
GO:0045505	dynein intermediate chain binding	7/4842	36/18639	0.194444444444444	0.748502684840975	0.862727275659906	1
GO:0017069	snRNA binding	11/4842	54/18639	0.203703703703704	0.784145669833402	0.865006657846788	1
GO:0005104	fibroblast growth factor receptor binding	5/4842	27/18639	0.185185185185185	0.712859699848547	0.867609029554273	1
GO:0008266	poly(U) RNA binding	5/4842	27/18639	0.185185185185185	0.712859699848547	0.867609029554273	1
GO:0098631	cell adhesion mediator activity	16/4842	76/18639	0.210526315789474	0.810408921933085	0.868311175313614	1
GO:0008236	serine-type peptidase activity	44/4842	194/18639	0.22680412371134	0.873069405587705	0.872735789533813	1
GO:0031369	translation initiation factor binding	6/4842	32/18639	0.1875	0.721770446096654	0.874454674300694	1
GO:0070717	poly-purine tract binding	6/4842	32/18639	0.1875	0.721770446096654	0.874454674300694	1
GO:0008509	monoatomic anion transmembrane transporter activity	33/4842	149/18639	0.221476510067114	0.852561063845713	0.879072143547636	1
GO:0141108	transporter regulator activity	38/4842	170/18639	0.223529411764706	0.860463590640717	0.880298461152674	1
GO:0098632	cell-cell adhesion mediator activity	11/4842	55/18639	0.2	0.769888475836431	0.880544799177056	1
GO:0000400	four-way junction DNA binding	3/4842	18/18639	0.166666666666667	0.641573729863693	0.883659175268244	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/4842	18/18639	0.166666666666667	0.641573729863693	0.883659175268244	1
GO:0022851	GABA-gated chloride ion channel activity	3/4842	18/18639	0.166666666666667	0.641573729863693	0.883659175268244	1
GO:0098641	cadherin binding involved in cell-cell adhesion	3/4842	18/18639	0.166666666666667	0.641573729863693	0.883659175268244	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	4/4842	23/18639	0.173913043478261	0.669468239857766	0.884617940234907	1
GO:0099186	structural constituent of postsynapse	4/4842	23/18639	0.173913043478261	0.669468239857766	0.884617940234907	1
GO:0016597	amino acid binding	10/4842	51/18639	0.196078431372549	0.75479262336905	0.887413318497655	1
GO:0050698	proteoglycan sulfotransferase activity	5/4842	28/18639	0.178571428571429	0.687400424853956	0.88814720239479	1
GO:0051119	sugar transmembrane transporter activity	5/4842	28/18639	0.178571428571429	0.687400424853956	0.88814720239479	1
GO:0005542	folic acid binding	2/4842	13/18639	0.153846153846154	0.592221904489563	0.88866475674196	1
GO:0008417	fucosyltransferase activity	2/4842	13/18639	0.153846153846154	0.592221904489563	0.88866475674196	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/4842	13/18639	0.153846153846154	0.592221904489563	0.88866475674196	1
GO:0030955	potassium ion binding	2/4842	13/18639	0.153846153846154	0.592221904489563	0.88866475674196	1
GO:0070700	BMP receptor binding	2/4842	13/18639	0.153846153846154	0.592221904489563	0.88866475674196	1
GO:0140666	annealing activity	2/4842	13/18639	0.153846153846154	0.592221904489563	0.88866475674196	1
GO:0004867	serine-type endopeptidase inhibitor activity	20/4842	95/18639	0.210526315789474	0.810408921933085	0.889783825346914	1
GO:0005501	retinoid binding	7/4842	38/18639	0.184210526315789	0.70910780669145	0.898003789742642	1
GO:0019840	isoprenoid binding	7/4842	38/18639	0.184210526315789	0.70910780669145	0.898003789742642	1
GO:0016836	hydro-lyase activity	12/4842	61/18639	0.19672131147541	0.757267353281736	0.901296776048045	1
GO:0099106	ion channel regulator activity	35/4842	160/18639	0.21875	0.842065520446097	0.901385044480251	1
GO:0140767	enzyme-substrate adaptor activity	30/4842	139/18639	0.215827338129496	0.83081490198176	0.902270084763796	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	8/4842	43/18639	0.186046511627907	0.716175326359471	0.903315038624351	1
GO:0019957	C-C chemokine binding	4/4842	24/18639	0.166666666666667	0.641573729863693	0.904286843845614	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	4/4842	24/18639	0.166666666666667	0.641573729863693	0.904286843845614	1
GO:0015370	solute:sodium symporter activity	16/4842	79/18639	0.20253164556962	0.779633899581196	0.904537353669051	1
GO:0004890	GABA-A receptor activity	3/4842	19/18639	0.157894736842105	0.607806691449814	0.905447743470726	1
GO:0008301	DNA binding, bending	3/4842	19/18639	0.157894736842105	0.607806691449814	0.905447743470726	1
GO:0022821	solute:potassium antiporter activity	3/4842	19/18639	0.157894736842105	0.607806691449814	0.905447743470726	1
GO:0004629	phospholipase C activity	5/4842	29/18639	0.172413793103448	0.663696961927958	0.905880886317712	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	6/4842	34/18639	0.176470588235294	0.679313361032145	0.908863221332048	1
GO:0005313	L-glutamate transmembrane transporter activity	2/4842	14/18639	0.142857142857143	0.549920339883165	0.912402827803151	1
GO:0031404	chloride ion binding	2/4842	14/18639	0.142857142857143	0.549920339883165	0.912402827803151	1
GO:0032036	myosin heavy chain binding	2/4842	14/18639	0.142857142857143	0.549920339883165	0.912402827803151	1
GO:0042043	neurexin family protein binding	2/4842	14/18639	0.142857142857143	0.549920339883165	0.912402827803151	1
GO:0043176	amine binding	2/4842	14/18639	0.142857142857143	0.549920339883165	0.912402827803151	1
GO:0005544	calcium-dependent phospholipid binding	10/4842	53/18639	0.188679245283019	0.726309882864558	0.913702695418123	1
GO:0008146	sulfotransferase activity	10/4842	53/18639	0.188679245283019	0.726309882864558	0.913702695418123	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	10/4842	53/18639	0.188679245283019	0.726309882864558	0.913702695418123	1
GO:0015171	amino acid transmembrane transporter activity	21/4842	102/18639	0.205882352941176	0.792532254537503	0.915559540083272	1
GO:0051536	iron-sulfur cluster binding	15/4842	76/18639	0.197368421052632	0.759758364312268	0.918767949671042	1
GO:0005251	delayed rectifier potassium channel activity	4/4842	25/18639	0.16	0.615910780669145	0.92092341097932	1
GO:0017056	structural constituent of nuclear pore	4/4842	25/18639	0.16	0.615910780669145	0.92092341097932	1
GO:0008187	poly-pyrimidine tract binding	5/4842	30/18639	0.166666666666667	0.641573729863693	0.921105249200983	1
GO:0001972	retinoic acid binding	3/4842	20/18639	0.15	0.577416356877323	0.923471048296561	1
GO:0140939	histone H4 methyltransferase activity	3/4842	20/18639	0.15	0.577416356877323	0.923471048296561	1
GO:0001664	G protein-coupled receptor binding	67/4842	297/18639	0.225589225589226	0.868392725270049	0.924040386543271	1
GO:0005200	structural constituent of cytoskeleton	23/4842	112/18639	0.205357142857143	0.79051048858205	0.925934657397976	1
GO:0005201	extracellular matrix structural constituent	36/4842	168/18639	0.214285714285714	0.824880509824748	0.927318381459129	1
GO:0016247	channel regulator activity	36/4842	168/18639	0.214285714285714	0.824880509824748	0.927318381459129	1
GO:0051540	metal cluster binding	15/4842	77/18639	0.194805194805195	0.749891372567952	0.927800932198376	1
GO:0004129	cytochrome-c oxidase activity	2/4842	15/18639	0.133333333333333	0.513258983890954	0.931323675853122	1
GO:0015116	sulfate transmembrane transporter activity	2/4842	15/18639	0.133333333333333	0.513258983890954	0.931323675853122	1
GO:0015250	water channel activity	2/4842	15/18639	0.133333333333333	0.513258983890954	0.931323675853122	1
GO:0051371	muscle alpha-actinin binding	2/4842	15/18639	0.133333333333333	0.513258983890954	0.931323675853122	1
GO:0055105	ubiquitin-protein transferase inhibitor activity	2/4842	15/18639	0.133333333333333	0.513258983890954	0.931323675853122	1
GO:0047499	calcium-independent phospholipase A2 activity	5/4842	31/18639	0.161290322580645	0.620877803093896	0.934105777830331	1
GO:0055106	ubiquitin-protein transferase regulator activity	6/4842	36/18639	0.166666666666667	0.641573729863693	0.934781171884653	1
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	25/4842	122/18639	0.204918032786885	0.788820159668475	0.934902131522533	1
GO:0001637	G protein-coupled chemoattractant receptor activity	4/4842	26/18639	0.153846153846154	0.592221904489563	0.934914917179074	1
GO:0004950	chemokine receptor activity	4/4842	26/18639	0.153846153846154	0.592221904489563	0.934914917179074	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	7/4842	41/18639	0.170731707317073	0.657221869616466	0.936334176828389	1
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/4842	21/18639	0.142857142857143	0.549920339883165	0.938292296633087	1
GO:1904047	S-adenosyl-L-methionine binding	3/4842	21/18639	0.142857142857143	0.549920339883165	0.938292296633087	1
GO:0005254	chloride channel activity	16/4842	83/18639	0.192771084337349	0.74206118152909	0.939721810760591	1
GO:0046943	carboxylic acid transmembrane transporter activity	40/4842	188/18639	0.212765957446809	0.819030293443012	0.943226859525324	1
GO:0042805	actinin binding	6/4842	37/18639	0.162162162162162	0.624233899326836	0.945101734013821	1
GO:0031492	nucleosomal DNA binding	7/4842	42/18639	0.166666666666667	0.641573729863693	0.945932565467397	1
GO:0003688	DNA replication origin binding	2/4842	16/18639	0.125	0.48118029739777	0.946327643632071	1
GO:0015385	sodium:proton antiporter activity	2/4842	16/18639	0.125	0.48118029739777	0.946327643632071	1
GO:0016675	oxidoreductase activity, acting on a heme group of donors	2/4842	16/18639	0.125	0.48118029739777	0.946327643632071	1
GO:0055102	lipase inhibitor activity	2/4842	16/18639	0.125	0.48118029739777	0.946327643632071	1
GO:0008395	steroid hydroxylase activity	4/4842	27/18639	0.148148148148148	0.570287759878838	0.946620288939909	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/4842	27/18639	0.148148148148148	0.570287759878838	0.946620288939909	1
GO:0005342	organic acid transmembrane transporter activity	40/4842	189/18639	0.211640211640212	0.814696799826911	0.947757946275114	1
GO:0001094	TFIID-class transcription factor complex binding	1/4842	10/18639	0.1	0.384944237918216	0.950653944718324	1
GO:0003796	lysozyme activity	1/4842	10/18639	0.1	0.384944237918216	0.950653944718324	1
GO:0008401	retinoic acid 4-hydroxylase activity	1/4842	10/18639	0.1	0.384944237918216	0.950653944718324	1
GO:0008519	ammonium channel activity	1/4842	10/18639	0.1	0.384944237918216	0.950653944718324	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/4842	10/18639	0.1	0.384944237918216	0.950653944718324	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/4842	10/18639	0.1	0.384944237918216	0.950653944718324	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/4842	10/18639	0.1	0.384944237918216	0.950653944718324	1
GO:0019531	oxalate transmembrane transporter activity	1/4842	10/18639	0.1	0.384944237918216	0.950653944718324	1
GO:0031996	thioesterase binding	1/4842	10/18639	0.1	0.384944237918216	0.950653944718324	1
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/4842	10/18639	0.1	0.384944237918216	0.950653944718324	1
GO:0047429	nucleoside triphosphate diphosphatase activity	1/4842	10/18639	0.1	0.384944237918216	0.950653944718324	1
GO:0051378	serotonin binding	1/4842	10/18639	0.1	0.384944237918216	0.950653944718324	1
GO:0070097	delta-catenin binding	1/4842	10/18639	0.1	0.384944237918216	0.950653944718324	1
GO:0097177	mitochondrial ribosome binding	1/4842	10/18639	0.1	0.384944237918216	0.950653944718324	1
GO:0009055	electron transfer activity	23/4842	116/18639	0.198275862068966	0.763251506217152	0.95092903440524	1
GO:0005253	monoatomic anion channel activity	20/4842	103/18639	0.194174757281553	0.747464539647021	0.952643500732487	1
GO:0045499	chemorepellent activity	4/4842	28/18639	0.142857142857143	0.549920339883165	0.956365803364095	1
GO:0051393	alpha-actinin binding	4/4842	28/18639	0.142857142857143	0.549920339883165	0.956365803364095	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	10/4842	58/18639	0.172413793103448	0.663696961927958	0.957696280869848	1
GO:0004549	tRNA-specific ribonuclease activity	2/4842	17/18639	0.117647058823529	0.45287557402143	0.958172477104502	1
GO:0005212	structural constituent of eye lens	3/4842	23/18639	0.130434782608696	0.502101179893325	0.960285704156568	1
GO:0016493	C-C chemokine receptor activity	3/4842	23/18639	0.130434782608696	0.502101179893325	0.960285704156568	1
GO:0016917	GABA receptor activity	3/4842	23/18639	0.130434782608696	0.502101179893325	0.960285704156568	1
GO:0008083	growth factor activity	33/4842	162/18639	0.203703703703704	0.784145669833402	0.960550763160767	1
GO:0003925	G protein activity	9/4842	54/18639	0.166666666666667	0.641573729863693	0.96256223472387	1
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/4842	11/18639	0.0909090909090909	0.349949307198378	0.963479839810593	1
GO:0008199	ferric iron binding	1/4842	11/18639	0.0909090909090909	0.349949307198378	0.963479839810593	1
GO:0016594	glycine binding	1/4842	11/18639	0.0909090909090909	0.349949307198378	0.963479839810593	1
GO:0019206	nucleoside kinase activity	1/4842	11/18639	0.0909090909090909	0.349949307198378	0.963479839810593	1
GO:0031731	CCR6 chemokine receptor binding	1/4842	11/18639	0.0909090909090909	0.349949307198378	0.963479839810593	1
GO:0034511	U3 snoRNA binding	1/4842	11/18639	0.0909090909090909	0.349949307198378	0.963479839810593	1
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/4842	11/18639	0.0909090909090909	0.349949307198378	0.963479839810593	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/4842	11/18639	0.0909090909090909	0.349949307198378	0.963479839810593	1
GO:1990948	ubiquitin ligase inhibitor activity	1/4842	11/18639	0.0909090909090909	0.349949307198378	0.963479839810593	1
GO:0004252	serine-type endopeptidase activity	36/4842	176/18639	0.204545454545455	0.78738594119635	0.963948775890289	1
GO:0015078	proton transmembrane transporter activity	38/4842	185/18639	0.205405405405405	0.790696272480659	0.965021002208802	1
GO:0003746	translation elongation factor activity	2/4842	18/18639	0.111111111111111	0.427715819909128	0.967486639834034	1
GO:0015172	acidic amino acid transmembrane transporter activity	2/4842	18/18639	0.111111111111111	0.427715819909128	0.967486639834034	1
GO:0001091	RNA polymerase II general transcription initiation factor binding	3/4842	24/18639	0.125	0.48118029739777	0.968285541343847	1
GO:0048027	mRNA 5'-UTR binding	3/4842	24/18639	0.125	0.48118029739777	0.968285541343847	1
GO:0004623	phospholipase A2 activity	5/4842	35/18639	0.142857142857143	0.549920339883165	0.968960966155416	1
GO:0046982	protein heterodimerization activity	81/4842	369/18639	0.219512195121951	0.844999546649742	0.968975427675428	1
GO:0033612	receptor serine/threonine kinase binding	4/4842	30/18639	0.133333333333333	0.513258983890954	0.971110796382368	1
GO:0005272	sodium channel activity	8/4842	51/18639	0.156862745098039	0.60383409869524	0.972550333294964	1
GO:0003720	telomerase activity	1/4842	12/18639	0.0833333333333333	0.320786864931846	0.972972572022162	1
GO:0004032	aldose reductase (NADPH) activity	1/4842	12/18639	0.0833333333333333	0.320786864931846	0.972972572022162	1
GO:0004859	phospholipase inhibitor activity	1/4842	12/18639	0.0833333333333333	0.320786864931846	0.972972572022162	1
GO:0008504	monoamine transmembrane transporter activity	1/4842	12/18639	0.0833333333333333	0.320786864931846	0.972972572022162	1
GO:0010853	cyclase activator activity	1/4842	12/18639	0.0833333333333333	0.320786864931846	0.972972572022162	1
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	1/4842	12/18639	0.0833333333333333	0.320786864931846	0.972972572022162	1
GO:0004812	aminoacyl-tRNA ligase activity	6/4842	41/18639	0.146341463414634	0.563333031099828	0.973247086652264	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	6/4842	41/18639	0.146341463414634	0.563333031099828	0.973247086652264	1
GO:0005229	intracellularly calcium-gated chloride channel activity	2/4842	19/18639	0.105263157894737	0.405204460966543	0.974785333523835	1
GO:0034987	immunoglobulin receptor binding	2/4842	19/18639	0.105263157894737	0.405204460966543	0.974785333523835	1
GO:0042834	peptidoglycan binding	2/4842	19/18639	0.105263157894737	0.405204460966543	0.974785333523835	1
GO:0141147	intracellularly calcium-gated channel activity	2/4842	19/18639	0.105263157894737	0.405204460966543	0.974785333523835	1
GO:0005504	fatty acid binding	7/4842	47/18639	0.148936170212766	0.573321205410108	0.97710213400432	1
GO:0008307	structural constituent of muscle	6/4842	42/18639	0.142857142857143	0.549920339883165	0.977799506849742	1
GO:0022829	wide pore channel activity	5/4842	37/18639	0.135135135135135	0.520194916105697	0.979063227165535	1
GO:0004435	phosphatidylinositol phospholipase C activity	3/4842	26/18639	0.115384615384615	0.444166428367172	0.979939113208092	1
GO:0008143	poly(A) binding	3/4842	26/18639	0.115384615384615	0.444166428367172	0.979939113208092	1
GO:0015145	monosaccharide transmembrane transporter activity	3/4842	26/18639	0.115384615384615	0.444166428367172	0.979939113208092	1
GO:0003964	RNA-directed DNA polymerase activity	1/4842	13/18639	0.0769230769230769	0.296110952244781	0.979998223295512	1
GO:0004993	G protein-coupled serotonin receptor activity	1/4842	13/18639	0.0769230769230769	0.296110952244781	0.979998223295512	1
GO:1901338	catecholamine binding	1/4842	13/18639	0.0769230769230769	0.296110952244781	0.979998223295512	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/4842	20/18639	0.1	0.384944237918216	0.98048692077131	1
GO:0010851	cyclase regulator activity	2/4842	20/18639	0.1	0.384944237918216	0.98048692077131	1
GO:0043024	ribosomal small subunit binding	2/4842	20/18639	0.1	0.384944237918216	0.98048692077131	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	11/4842	68/18639	0.161764705882353	0.622703914279466	0.980768281108216	1
GO:0047498	calcium-dependent phospholipase A2 activity	4/4842	32/18639	0.125	0.48118029739777	0.981084556048622	1
GO:0005245	voltage-gated calcium channel activity	6/4842	43/18639	0.13953488372093	0.537131494769603	0.981623323074351	1
GO:0015459	potassium channel regulator activity	9/4842	59/18639	0.152542372881356	0.587203074790498	0.983401817477236	1
GO:0015252	proton channel activity	3/4842	27/18639	0.111111111111111	0.427715819909128	0.984103966241615	1
GO:0005248	voltage-gated sodium channel activity	2/4842	21/18639	0.0952380952380952	0.36661355992211	0.98492846015428	1
GO:0051428	peptide hormone receptor binding	2/4842	21/18639	0.0952380952380952	0.36661355992211	0.98492846015428	1
GO:0008392	arachidonate epoxygenase activity	1/4842	14/18639	0.0714285714285714	0.274960169941583	0.985197869102617	1
GO:0061783	peptidoglycan muralytic activity	1/4842	14/18639	0.0714285714285714	0.274960169941583	0.985197869102617	1
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/4842	14/18639	0.0714285714285714	0.274960169941583	0.985197869102617	1
GO:1990825	sequence-specific mRNA binding	1/4842	14/18639	0.0714285714285714	0.274960169941583	0.985197869102617	1
GO:0005125	cytokine activity	47/4842	234/18639	0.200854700854701	0.77317859752804	0.985819252770933	1
GO:0015081	sodium ion transmembrane transporter activity	31/4842	164/18639	0.189024390243902	0.727638498503944	0.987023570166037	1
GO:0005242	inward rectifier potassium channel activity	3/4842	28/18639	0.107142857142857	0.412440254912374	0.987432545786917	1
GO:0051537	2 iron, 2 sulfur cluster binding	3/4842	28/18639	0.107142857142857	0.412440254912374	0.987432545786917	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	4/4842	34/18639	0.117647058823529	0.45287557402143	0.98773734637786	1
GO:0051427	hormone receptor binding	4/4842	34/18639	0.117647058823529	0.45287557402143	0.98773734637786	1
GO:0005243	gap junction channel activity	2/4842	22/18639	0.0909090909090909	0.349949307198378	0.988379706587812	1
GO:0005523	tropomyosin binding	1/4842	15/18639	0.0666666666666667	0.256629491945477	0.989046025763295	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/4842	15/18639	0.0666666666666667	0.256629491945477	0.989046025763295	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/4842	15/18639	0.0666666666666667	0.256629491945477	0.989046025763295	1
GO:0030553	cGMP binding	1/4842	15/18639	0.0666666666666667	0.256629491945477	0.989046025763295	1
GO:0008137	NADH dehydrogenase (ubiquinone) activity	5/4842	41/18639	0.121951219512195	0.46944419258319	0.990750892902563	1
GO:0008391	arachidonate monooxygenase activity	1/4842	16/18639	0.0625	0.240590148698885	0.991893917905376	1
GO:0099094	ligand-gated monoatomic cation channel activity	24/4842	136/18639	0.176470588235294	0.679313361032145	0.991932823305876	1
GO:0015149	hexose transmembrane transporter activity	2/4842	24/18639	0.0833333333333333	0.320786864931846	0.993125306278172	1
GO:0055056	D-glucose transmembrane transporter activity	2/4842	24/18639	0.0833333333333333	0.320786864931846	0.993125306278172	1
GO:0009881	photoreceptor activity	1/4842	17/18639	0.0588235294117647	0.226437787010715	0.994001507955431	1
GO:0030548	acetylcholine receptor regulator activity	1/4842	17/18639	0.0588235294117647	0.226437787010715	0.994001507955431	1
GO:0003954	NADH dehydrogenase activity	5/4842	44/18639	0.113636363636364	0.437436633997972	0.995099971732616	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/4842	18/18639	0.0555555555555556	0.213857909954564	0.995561206080219	1
GO:0099602	neurotransmitter receptor regulator activity	1/4842	18/18639	0.0555555555555556	0.213857909954564	0.995561206080219	1
GO:0015079	potassium ion transmembrane transporter activity	28/4842	160/18639	0.175	0.673652416356877	0.995894384699092	1
GO:0099589	serotonin receptor activity	1/4842	19/18639	0.0526315789473684	0.202602230483271	0.99671542122224	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	5/4842	46/18639	0.108695652173913	0.418417649911104	0.99682190967919	1
GO:0099095	ligand-gated monoatomic anion channel activity	5/4842	47/18639	0.106382978723404	0.409515146721506	0.997447196912945	1
GO:0005326	neurotransmitter transmembrane transporter activity	1/4842	20/18639	0.05	0.192472118959108	0.997569552824921	1
GO:0030627	pre-mRNA 5'-splice site binding	1/4842	20/18639	0.05	0.192472118959108	0.997569552824921	1
GO:0004497	monooxygenase activity	16/4842	106/18639	0.150943396226415	0.581047906291646	0.997578062456065	1
GO:0070182	DNA polymerase binding	1/4842	21/18639	0.0476190476190476	0.183306779961055	0.998201607458453	1
GO:0008135	translation factor activity, RNA binding	11/4842	83/18639	0.132530120481928	0.51016706230125	0.998476528007639	1
GO:0048019	receptor antagonist activity	2/4842	30/18639	0.0666666666666667	0.256629491945477	0.998619924196543	1
GO:0180051	translation factor activity	11/4842	84/18639	0.130952380952381	0.504093644892901	0.99872981836412	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	4/4842	44/18639	0.0909090909090909	0.349949307198378	0.998752377953132	1
GO:0030547	signaling receptor inhibitor activity	4/4842	44/18639	0.0909090909090909	0.349949307198378	0.998752377953132	1
GO:0003823	antigen binding	29/4842	174/18639	0.166666666666667	0.641573729863693	0.998771416061475	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/4842	31/18639	0.0645161290322581	0.248351121237558	0.998947858940033	1
GO:0003743	translation initiation factor activity	5/4842	51/18639	0.0980392156862745	0.377396311684525	0.99895402859574	1
GO:0030515	snoRNA binding	2/4842	32/18639	0.0625	0.240590148698885	0.999198584742554	1
GO:0005249	voltage-gated potassium channel activity	13/4842	98/18639	0.13265306122449	0.510640315605796	0.999305768969063	1
GO:0005267	potassium channel activity	18/4842	124/18639	0.145161290322581	0.558790022784507	0.999314494114722	1
GO:0071855	neuropeptide receptor binding	3/4842	40/18639	0.075	0.288708178438662	0.999345358471274	1
GO:0008227	G protein-coupled amine receptor activity	3/4842	41/18639	0.0731707317073171	0.281666515549914	0.999492712329984	1
GO:0019825	oxygen binding	2/4842	34/18639	0.0588235294117647	0.226437787010715	0.999536182893636	1
GO:0022832	voltage-gated channel activity	27/4842	175/18639	0.154285714285714	0.593913967073818	0.999727486182422	1
GO:0030280	structural constituent of skin epidermis	2/4842	37/18639	0.0540540540540541	0.208077966442279	0.999796924411269	1
GO:0005244	voltage-gated monoatomic ion channel activity	26/4842	173/18639	0.15028901734104	0.578528912478243	0.999825103524483	1
GO:0022843	voltage-gated monoatomic cation channel activity	20/4842	143/18639	0.13986013986014	0.538383549535966	0.999836212734783	1
GO:0005184	neuropeptide hormone activity	1/4842	31/18639	0.032258064516129	0.124175560618779	0.999911607284034	1
GO:0160041	neuropeptide activity	1/4842	32/18639	0.03125	0.120295074349442	0.999934608011179	1
GO:0015276	ligand-gated monoatomic ion channel activity	27/4842	186/18639	0.145161290322581	0.558790022784507	0.999948993395401	1
GO:0042923	neuropeptide binding	1/4842	33/18639	0.0303030303030303	0.116649769066126	0.999951624618363	1
GO:0005261	monoatomic cation channel activity	59/4842	341/18639	0.173020527859238	0.666032552409816	0.9999527453728	1
GO:0019843	rRNA binding	5/4842	65/18639	0.0769230769230769	0.296110952244781	0.99996080323351	1
GO:0022834	ligand-gated channel activity	27/4842	188/18639	0.143617021276596	0.552845448074033	0.999962797754148	1
GO:0008528	G protein-coupled peptide receptor activity	14/4842	122/18639	0.114754098360656	0.441739289414346	0.99997814978582	1
GO:0001653	peptide receptor activity	15/4842	128/18639	0.1171875	0.451106528810409	0.999979787033612	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/4842	36/18639	0.0277777777777778	0.106928954977282	0.99998041720355	1
GO:0005216	monoatomic ion channel activity	78/4842	448/18639	0.174107142857143	0.670215414232608	0.999994909388313	1
GO:0005179	hormone activity	14/4842	132/18639	0.106060606060606	0.408274191731441	0.99999699455062	1
GO:0022824	transmitter-gated monoatomic ion channel activity	3/4842	63/18639	0.0476190476190476	0.183306779961055	0.99999849185546	1
GO:0022835	transmitter-gated channel activity	3/4842	63/18639	0.0476190476190476	0.183306779961055	0.99999849185546	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	4/4842	73/18639	0.0547945205479452	0.210928349544228	0.999999147387781	1
GO:0022836	gated channel activity	47/4842	318/18639	0.147798742138365	0.568942741577237	0.999999588034844	1
GO:0030594	neurotransmitter receptor activity	6/4842	97/18639	0.0618556701030928	0.238109837887556	0.999999919032686	1
GO:0003730	mRNA 3'-UTR binding	28/4842	262/18639	0.106870229007634	0.411390788614887	0.999999999836875	1
GO:0003735	structural constituent of ribosome	2/4842	175/18639	0.0114285714285714	0.0439936271906532	1	1
GO:0030371	translation repressor activity	12/4842	329/18639	0.0364741641337386	0.140405193161659	1	1
GO:0045182	translation regulator activity	16/4842	356/18639	0.0449438202247191	0.173008646255378	1	1
GO:1903231	mRNA base-pairing translational repressor activity	2/4842	298/18639	0.00671140939597315	0.0258351837529004	1	1