ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003779	actin binding	77/1670	443/18639	0.173814898419865	1.93996161176518	1.06631806435384e-08	8.14452368098499e-06
GO:0023026	MHC class II protein complex binding	14/1670	27/18639	0.518518518518518	5.7872255489022	1.33298259917921e-08	8.14452368098499e-06
GO:0023023	MHC protein complex binding	16/1670	37/18639	0.432432432432432	4.8264120407833	3.34369744480399e-08	1.36199942585016e-05
GO:0045296	cadherin binding	60/1670	334/18639	0.179640718562874	2.00498404388827	1.37236194461686e-07	4.19256574080451e-05
GO:0003714	transcription corepressor activity	42/1670	204/18639	0.205882352941176	2.29786896794646	2.47821715242432e-07	6.05676272052504e-05
GO:0019955	cytokine binding	33/1670	144/18639	0.229166666666667	2.55774700598802	3.69846320408489e-07	7.5325367256529e-05
GO:0005126	cytokine receptor binding	50/1670	275/18639	0.181818181818182	2.02928688078389	1.02893170816937e-06	0.000179622078197568
GO:0048306	calcium-dependent protein binding	22/1670	80/18639	0.275	3.06929640718563	1.28766925944659e-06	0.000196691479380467
GO:0044389	ubiquitin-like protein ligase binding	55/1670	322/18639	0.170807453416149	1.90639528396623	2.30437735630855e-06	0.000312883236601005
GO:0004857	enzyme inhibitor activity	66/1670	416/18639	0.158653846153846	1.77074792722248	3.34813809442922e-06	0.000409142475139251
GO:0140375	immune receptor activity	32/1670	156/18639	0.205128205128205	2.28945186549977	6.97050589905837e-06	0.000752275299077364
GO:0031625	ubiquitin protein ligase binding	51/1670	302/18639	0.16887417218543	1.88481778165523	7.38731881254367e-06	0.000752275299077364
GO:0098641	cadherin binding involved in cell-cell adhesion	9/1670	18/18639	0.5	5.58053892215569	8.37834108355077e-06	0.000787564061853772
GO:0038024	cargo receptor activity	18/1670	65/18639	0.276923076923077	3.09076001842469	1.04870485106022e-05	0.000915369519996845
GO:0042605	peptide antigen binding	14/1670	45/18639	0.311111111111111	3.47233532934132	2.36488598876549e-05	0.00186481270029814
GO:0001221	transcription coregulator binding	25/1670	115/18639	0.217391304347826	2.42632127050247	2.44165329007939e-05	0.00186481270029814
GO:0005543	phospholipid binding	72/1670	497/18639	0.144869215291751	1.61689658911553	3.07143130037681e-05	0.00220781708768262
GO:0042277	peptide binding	42/1670	249/18639	0.168674698795181	1.88259144361879	4.69715613717376e-05	0.00309457553550949
GO:0003712	transcription coregulator activity	71/1670	495/18639	0.143434343434343	1.6008818726184	4.81153315668415e-05	0.00309457553550949
GO:0032395	MHC class II receptor activity	6/1670	10/18639	0.6	6.69664670658683	7.8424956834731e-05	0.00479176486260206
GO:0030695	GTPase regulator activity	69/1670	489/18639	0.141104294478528	1.57487601484148	0.000101695276967468	0.00575167618629934
GO:0001540	amyloid-beta binding	19/1670	83/18639	0.228915662650602	2.5549455306255	0.000107871827225604	0.00575167618629934
GO:0060589	nucleoside-triphosphatase regulator activity	69/1670	490/18639	0.140816326530612	1.57166198215813	0.00010825577110056	0.00575167618629934
GO:0072341	modified amino acid binding	20/1670	91/18639	0.21978021978022	2.4529841416069	0.000131022231394159	0.00667121528181928
GO:0005096	GTPase activator activity	43/1670	271/18639	0.158671586715867	1.7709459310162	0.000161874756212616	0.00725709142470651
GO:0005518	collagen binding	17/1670	72/18639	0.236111111111111	2.63525449101796	0.000163786783466156	0.00725709142470651
GO:0140297	DNA-binding transcription factor binding	68/1670	488/18639	0.139344262295082	1.55523215863355	0.000165687014985491	0.00725709142470651
GO:0019902	phosphatase binding	33/1670	190/18639	0.173684210526316	1.93850299401198	0.000166283600566107	0.00725709142470651
GO:0043394	proteoglycan binding	11/1670	37/18639	0.297297297297297	3.31815827803852	0.000275727218074931	0.0116185744995713
GO:0019207	kinase regulator activity	44/1670	287/18639	0.153310104529617	1.71110601097457	0.00029863888121691	0.0121645570949022
GO:0019887	protein kinase regulator activity	40/1670	255/18639	0.156862745098039	1.75075730891159	0.000342441092153195	0.0132916547578896
GO:0051020	GTPase binding	47/1670	315/18639	0.149206349206349	1.66530367835757	0.000356449124305152	0.0132916547578896
GO:0001223	transcription coactivator binding	12/1670	44/18639	0.272727272727273	3.04393032117583	0.000358939940270341	0.0132916547578896
GO:0030296	protein tyrosine kinase activator activity	10/1670	33/18639	0.303030303030303	3.38214480130648	0.00043869771737626	0.0157673120774644
GO:0051015	actin filament binding	34/1670	209/18639	0.162679425837321	1.81567773543821	0.000472238917554841	0.0164878844929147
GO:0046332	SMAD binding	17/1670	79/18639	0.215189873417722	2.4017509285227	0.000529329475406352	0.0179677949707378
GO:0001786	phosphatidylserine binding	14/1670	59/18639	0.23728813559322	2.64839135288745	0.000572300590927158	0.0189013870841348
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	50/1670	349/18639	0.143266475644699	1.59900828715063	0.000614020816691872	0.0197456167894071
GO:0031267	small GTPase binding	42/1670	283/18639	0.148409893992933	1.65641437972112	0.000795997785193052	0.0236032910935524
GO:0042625	ATPase-coupled ion transmembrane transporter activity	8/1670	24/18639	0.333333333333333	3.72035928143713	0.000811242410744026	0.0236032910935524
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	8/1670	24/18639	0.333333333333333	3.72035928143713	0.000811242410744026	0.0236032910935524
GO:0046961	proton-transporting ATPase activity, rotational mechanism	8/1670	24/18639	0.333333333333333	3.72035928143713	0.000811242410744026	0.0236032910935524
GO:0098632	cell-cell adhesion mediator activity	13/1670	55/18639	0.236363636363636	2.63807294501905	0.000926232030454225	0.0257239895730696
GO:0140313	molecular sequestering activity	13/1670	55/18639	0.236363636363636	2.63807294501905	0.000926232030454225	0.0257239895730696
GO:0019838	growth factor binding	24/1670	136/18639	0.176470588235294	1.96960197252554	0.000969349263249473	0.0263232177709079
GO:0001222	transcription corepressor binding	12/1670	49/18639	0.244897959183673	2.73332518636197	0.00103212648606688	0.0274186644776897
GO:0004860	protein kinase inhibitor activity	17/1670	84/18639	0.202380952380952	2.25878956372968	0.00110291804346328	0.0286758691300452
GO:0005041	low-density lipoprotein particle receptor activity	6/1670	15/18639	0.4	4.46443113772455	0.00126068596601241	0.0320949635513993
GO:0016209	antioxidant activity	17/1670	86/18639	0.197674418604651	2.2062595738755	0.00144838510300798	0.0358021916094109
GO:0019209	kinase activator activity	25/1670	148/18639	0.168918918918919	1.88531720343098	0.00146490145701354	0.0358021916094109
GO:0071813	lipoprotein particle binding	9/1670	32/18639	0.28125	3.13905314371257	0.0015252012933541	0.0358422303938214
GO:0071814	protein-lipid complex binding	9/1670	32/18639	0.28125	3.13905314371257	0.0015252012933541	0.0358422303938214
GO:0019864	IgG binding	5/1670	11/18639	0.454545454545455	5.07321720195972	0.00167231133244555	0.038557819778273
GO:0022853	active monoatomic ion transmembrane transporter activity	21/1670	118/18639	0.177966101694915	1.98629351466558	0.0017519097681545	0.0396450691978667
GO:0016675	oxidoreductase activity, acting on a heme group of donors	6/1670	16/18639	0.375	4.18540419161677	0.0018651837022491	0.0414409906208799
GO:0140311	protein sequestering activity	9/1670	33/18639	0.272727272727273	3.04393032117583	0.00193264013434579	0.0421729686459028
GO:0019003	GDP binding	15/1670	75/18639	0.2	2.23221556886228	0.00238630699803916	0.0500652929901999
GO:0019210	kinase inhibitor activity	17/1670	90/18639	0.188888888888889	2.10820359281437	0.00241716016993176	0.0500652929901999
GO:0035591	signaling adaptor activity	22/1670	129/18639	0.170542635658915	1.90343963236318	0.00241722773029607	0.0500652929901999
GO:0042578	phosphoric ester hydrolase activity	49/1670	363/18639	0.134986225895317	1.50659177512743	0.00248566168265234	0.0505817271007122
GO:0005085	guanyl-nucleotide exchange factor activity	34/1670	230/18639	0.147826086956522	1.64989846394168	0.00254578244552751	0.0505817271007122
GO:0004859	phospholipase inhibitor activity	5/1670	12/18639	0.416666666666667	4.65044910179641	0.00265635970014681	0.0505817271007122
GO:0008429	phosphatidylethanolamine binding	6/1670	17/18639	0.352941176470588	3.93920394505107	0.00266588876266513	0.0505817271007122
GO:0036041	long-chain fatty acid binding	6/1670	17/18639	0.352941176470588	3.93920394505107	0.00266588876266513	0.0505817271007122
GO:0017022	myosin binding	15/1670	76/18639	0.197368421052632	2.20284431137725	0.00273190997434288	0.0505817271007122
GO:0098631	cell adhesion mediator activity	15/1670	76/18639	0.197368421052632	2.20284431137725	0.00273190997434288	0.0505817271007122
GO:0030295	protein kinase activator activity	23/1670	139/18639	0.165467625899281	1.84679705337526	0.00291235116466472	0.0531178078092581
GO:0043236	laminin binding	8/1670	29/18639	0.275862068965517	3.07891802601693	0.00316072349925264	0.0568000605306871
GO:0005125	cytokine activity	34/1670	234/18639	0.145299145299145	1.62169507139567	0.00337551035751261	0.059780777635948
GO:1990782	protein tyrosine kinase binding	20/1670	117/18639	0.170940170940171	1.90787655458314	0.00361394771969248	0.0619179160830735
GO:0005484	SNAP receptor activity	9/1670	36/18639	0.25	2.79026946107784	0.00369444057721789	0.0619179160830735
GO:0030228	lipoprotein particle receptor activity	6/1670	18/18639	0.333333333333333	3.72035928143713	0.00369886078074007	0.0619179160830735
GO:0034185	apolipoprotein binding	6/1670	18/18639	0.333333333333333	3.72035928143713	0.00369886078074007	0.0619179160830735
GO:0001968	fibronectin binding	8/1670	30/18639	0.266666666666667	2.9762874251497	0.00397686714848063	0.06432369191684
GO:0017154	semaphorin receptor activity	5/1670	13/18639	0.384615384615385	4.29272224781207	0.00400049147764308	0.06432369191684
GO:0035325	Toll-like receptor binding	5/1670	13/18639	0.384615384615385	4.29272224781207	0.00400049147764308	0.06432369191684
GO:0032813	tumor necrosis factor receptor superfamily binding	11/1670	50/18639	0.22	2.4554371257485	0.00408648428822425	0.0648530363663641
GO:0015078	proton transmembrane transporter activity	28/1670	185/18639	0.151351351351351	1.68924421427415	0.00416286966674154	0.0652182914456175
GO:0042379	chemokine receptor binding	14/1670	72/18639	0.194444444444444	2.17020958083832	0.00429218493998369	0.0663930379324059
GO:0019903	protein phosphatase binding	23/1670	144/18639	0.159722222222222	1.78267215568862	0.00457748801735578	0.0690651254056279
GO:0004866	endopeptidase inhibitor activity	25/1670	161/18639	0.15527950310559	1.73308662178748	0.0046788546443994	0.0690651254056279
GO:0005178	integrin binding	25/1670	161/18639	0.15527950310559	1.73308662178748	0.0046788546443994	0.0690651254056279
GO:0002020	protease binding	22/1670	136/18639	0.161764705882353	1.80546847481508	0.00469100278941663	0.0690651254056279
GO:0004896	cytokine receptor activity	17/1670	96/18639	0.177083333333333	1.97644086826347	0.00483878244071808	0.0703927636018749
GO:0005164	tumor necrosis factor receptor binding	8/1670	31/18639	0.258064516129032	2.88027815337068	0.00494632697671709	0.0711107243005681
GO:0120020	cholesterol transfer activity	7/1670	25/18639	0.28	3.12510179640719	0.00519034188052619	0.0727581712348515
GO:0003924	GTPase activity	44/1670	331/18639	0.132930513595166	1.48364781011994	0.00528779555409083	0.0727581712348515
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	16/1670	89/18639	0.179775280898876	2.0064859045953	0.00529908121104892	0.0727581712348515
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	16/1670	89/18639	0.179775280898876	2.0064859045953	0.00529908121104892	0.0727581712348515
GO:0008009	chemokine activity	10/1670	45/18639	0.222222222222222	2.48023952095808	0.0056254947242339	0.0763817172557092
GO:0032036	myosin heavy chain binding	5/1670	14/18639	0.357142857142857	3.98609923011121	0.00576846007599117	0.0766201979658827
GO:0044548	S100 protein binding	5/1670	14/18639	0.357142857142857	3.98609923011121	0.00576846007599117	0.0766201979658827
GO:0050840	extracellular matrix binding	13/1670	67/18639	0.194029850746269	2.16558226829922	0.00592015662952035	0.0769885905619111
GO:0140793	histone H2AXY142 phosphatase activity	16/1670	90/18639	0.177777777777778	1.98419161676647	0.00592219927399316	0.0769885905619111
GO:0061134	peptidase regulator activity	32/1670	226/18639	0.141592920353982	1.58032960627418	0.0064295672301409	0.0827045384761282
GO:0043548	phosphatidylinositol 3-kinase binding	7/1670	26/18639	0.269230769230769	3.00490557346845	0.00656262743617917	0.083536778406364
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	13/1670	68/18639	0.191176470588235	2.133735470236	0.00673366482102196	0.0839646776662126
GO:1990841	promoter-specific chromatin binding	13/1670	68/18639	0.191176470588235	2.133735470236	0.00673366482102196	0.0839646776662126
GO:0061135	endopeptidase regulator activity	27/1670	184/18639	0.146739130434783	1.63776685758917	0.00732713692397014	0.0904420335463789
GO:0019956	chemokine binding	8/1670	33/18639	0.242424242424242	2.70571584104518	0.00741600206695562	0.0906235452581977
GO:0001784	phosphotyrosine residue binding	10/1670	47/18639	0.212765957446809	2.37469741368327	0.00775351685351971	0.0938098771782285
GO:0004129	cytochrome-c oxidase activity	5/1670	15/18639	0.333333333333333	3.72035928143713	0.00802234713098057	0.0940113387644946
GO:0005523	tropomyosin binding	5/1670	15/18639	0.333333333333333	3.72035928143713	0.00802234713098057	0.0940113387644946
GO:0005044	scavenger receptor activity	7/1670	27/18639	0.259259259259259	2.8936127744511	0.00818720768755258	0.0940113387644946
GO:0001216	DNA-binding transcription activator activity	60/1670	491/18639	0.122199592668024	1.36387916631096	0.0083963018965388	0.0940113387644946
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	6/1670	21/18639	0.285714285714286	3.18887938408897	0.00856537349799191	0.0940113387644946
GO:0097110	scaffold protein binding	13/1670	70/18639	0.185714285714286	2.07277159965783	0.0086252772313574	0.0940113387644946
GO:0005131	growth hormone receptor binding	4/1670	10/18639	0.4	4.46443113772455	0.00867416503509603	0.0940113387644946
GO:0005345	purine nucleobase transmembrane transporter activity	4/1670	10/18639	0.4	4.46443113772455	0.00867416503509603	0.0940113387644946
GO:0005381	iron ion transmembrane transporter activity	4/1670	10/18639	0.4	4.46443113772455	0.00867416503509603	0.0940113387644946
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	4/1670	10/18639	0.4	4.46443113772455	0.00867416503509603	0.0940113387644946
GO:0070513	death domain binding	4/1670	10/18639	0.4	4.46443113772455	0.00867416503509603	0.0940113387644946
GO:0030414	peptidase inhibitor activity	25/1670	169/18639	0.14792899408284	1.65104701838926	0.00869335620326341	0.0940113387644946
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	59/1670	484/18639	0.121900826446281	1.36054461325283	0.00934890543256285	0.100213705601682
GO:0140789	histone phosphatase activity	21/1670	136/18639	0.154411764705882	1.72340172595985	0.00959285976752002	0.101934562051387
GO:0004722	protein serine/threonine phosphatase activity	17/1670	103/18639	0.16504854368932	1.84211964420673	0.00985890756594617	0.103858491772295
GO:0051019	mitogen-activated protein kinase binding	7/1670	28/18639	0.25	2.79026946107784	0.0100893222689651	0.105377365920303
GO:0016763	pentosyltransferase activity	10/1670	49/18639	0.204081632653061	2.27777098863498	0.0104530621983619	0.108251203444053
GO:0055102	lipase inhibitor activity	5/1670	16/18639	0.3125	3.48783682634731	0.010821057780404	0.110194438397114
GO:0070411	I-SMAD binding	5/1670	16/18639	0.3125	3.48783682634731	0.010821057780404	0.110194438397114
GO:0004197	cysteine-type endopeptidase activity	15/1670	88/18639	0.170454545454545	1.90245645073489	0.0111061633591433	0.112163071279943
GO:0070851	growth factor receptor binding	21/1670	139/18639	0.151079136690647	1.68620600525568	0.012181709933447	0.12196160698399
GO:0008432	JUN kinase binding	4/1670	11/18639	0.363636363636364	4.05857376156777	0.0126752242937535	0.12196160698399
GO:0015205	nucleobase transmembrane transporter activity	4/1670	11/18639	0.363636363636364	4.05857376156777	0.0126752242937535	0.12196160698399
GO:0032050	clathrin heavy chain binding	4/1670	11/18639	0.363636363636364	4.05857376156777	0.0126752242937535	0.12196160698399
GO:0042608	T cell receptor binding	4/1670	11/18639	0.363636363636364	4.05857376156777	0.0126752242937535	0.12196160698399
GO:1990948	ubiquitin ligase inhibitor activity	4/1670	11/18639	0.363636363636364	4.05857376156777	0.0126752242937535	0.12196160698399
GO:0015399	primary active transmembrane transporter activity	24/1670	166/18639	0.144578313253012	1.6136498088161	0.0130873216590903	0.124250668390259
GO:0004721	phosphoprotein phosphatase activity	25/1670	175/18639	0.142857142857143	1.59443969204448	0.0132675231113863	0.124250668390259
GO:0033218	amide binding	33/1670	247/18639	0.133603238866397	1.49115614923998	0.0132878700283744	0.124250668390259
GO:0004725	protein tyrosine phosphatase activity	16/1670	98/18639	0.163265306122449	1.82221679090798	0.0133198343364353	0.124250668390259
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	6/1670	23/18639	0.260869565217391	2.91158552460297	0.013653981255331	0.126402765863746
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	5/1670	17/18639	0.294117647058824	3.28266995420923	0.0142190448711285	0.129669200242679
GO:0070403	NAD+ binding	5/1670	17/18639	0.294117647058824	3.28266995420923	0.0142190448711285	0.129669200242679
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	11/1670	59/18639	0.186440677966102	2.08087892012585	0.014602916673924	0.131211501290699
GO:0045309	protein phosphorylated amino acid binding	11/1670	59/18639	0.186440677966102	2.08087892012585	0.014602916673924	0.131211501290699
GO:0030165	PDZ domain binding	14/1670	83/18639	0.168674698795181	1.88259144361879	0.0151347804041323	0.134997822290873
GO:0001664	G protein-coupled receptor binding	38/1670	297/18639	0.127946127946128	1.42801669388496	0.0161736176339875	0.143218556150237
GO:0141110	transporter inhibitor activity	9/1670	45/18639	0.2	2.23221556886228	0.0167977836278821	0.147137059737082
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	6/1670	24/18639	0.25	2.79026946107784	0.0168569462873908	0.147137059737082
GO:0004875	complement receptor activity	4/1670	12/18639	0.333333333333333	3.72035928143713	0.0176846565905568	0.149038967956278
GO:0005078	MAP-kinase scaffold activity	4/1670	12/18639	0.333333333333333	3.72035928143713	0.0176846565905568	0.149038967956278
GO:0035259	nuclear glucocorticoid receptor binding	4/1670	12/18639	0.333333333333333	3.72035928143713	0.0176846565905568	0.149038967956278
GO:0097371	MDM2/MDM4 family protein binding	4/1670	12/18639	0.333333333333333	3.72035928143713	0.0176846565905568	0.149038967956278
GO:0097677	STAT family protein binding	4/1670	12/18639	0.333333333333333	3.72035928143713	0.0176846565905568	0.149038967956278
GO:0005544	calcium-dependent phospholipid binding	10/1670	53/18639	0.188679245283019	2.10586374420969	0.017920014145338	0.14998806360002
GO:0015026	coreceptor activity	11/1670	61/18639	0.180327868852459	2.01265338176107	0.0185239434332773	0.153988155615407
GO:0030291	protein serine/threonine kinase inhibitor activity	9/1670	46/18639	0.195652173913043	2.18368914345223	0.0192726059507605	0.159129219404252
GO:0003925	G protein activity	10/1670	54/18639	0.185185185185185	2.06686626746507	0.0202815717537954	0.164824112653149
GO:0015485	cholesterol binding	10/1670	54/18639	0.185185185185185	2.06686626746507	0.0202815717537954	0.164824112653149
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	6/1670	25/18639	0.24	2.67865868263473	0.0205411371527164	0.164824112653149
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	6/1670	25/18639	0.24	2.67865868263473	0.0205411371527164	0.164824112653149
GO:0019199	transmembrane receptor protein kinase activity	13/1670	78/18639	0.166666666666667	1.86017964071856	0.0206367342356233	0.164824112653149
GO:0120015	sterol transfer activity	7/1670	32/18639	0.21875	2.44148577844311	0.0209599929685597	0.166318905244025
GO:0035091	phosphatidylinositol binding	36/1670	284/18639	0.126760563380282	1.41478451547609	0.0214236634546869	0.16890139833308
GO:1901681	sulfur compound binding	35/1670	275/18639	0.127272727272727	1.42050081654872	0.021835761587804	0.171046799104465
GO:0005504	fatty acid binding	9/1670	47/18639	0.191489361702128	2.13722767231494	0.0220008112632649	0.171241983208342
GO:0008081	phosphoric diester hydrolase activity	14/1670	87/18639	0.160919540229885	1.79603551517654	0.0221946824765367	0.171657607508404
GO:0043395	heparan sulfate proteoglycan binding	5/1670	19/18639	0.263157894736842	2.93712574850299	0.0230023947831665	0.175680790156434
GO:0140036	ubiquitin-modified protein reader activity	5/1670	19/18639	0.263157894736842	2.93712574850299	0.0230023947831665	0.175680790156434
GO:0005507	copper ion binding	11/1670	63/18639	0.174603174603175	1.94875962360992	0.0231759028714885	0.17590654229167
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	4/1670	13/18639	0.307692307692308	3.43417779824965	0.0237665077518518	0.177089466297334
GO:0008035	high-density lipoprotein particle binding	4/1670	13/18639	0.307692307692308	3.43417779824965	0.0237665077518518	0.177089466297334
GO:0089720	caspase binding	4/1670	13/18639	0.307692307692308	3.43417779824965	0.0237665077518518	0.177089466297334
GO:0019865	immunoglobulin binding	6/1670	26/18639	0.230769230769231	2.57563334868724	0.0247346900676776	0.182083079895795
GO:0030247	polysaccharide binding	6/1670	26/18639	0.230769230769231	2.57563334868724	0.0247346900676776	0.182083079895795
GO:0000149	SNARE binding	16/1670	106/18639	0.150943396226415	1.68469099536776	0.026500445941047	0.189374716070048
GO:0005539	glycosaminoglycan binding	31/1670	242/18639	0.128099173553719	1.42972484782501	0.0272664130542284	0.189374716070048
GO:0001618	virus receptor activity	13/1670	81/18639	0.160493827160494	1.79128409846973	0.0274298893162017	0.189374716070048
GO:0033192	calmodulin-dependent protein phosphatase activity	13/1670	81/18639	0.160493827160494	1.79128409846973	0.0274298893162017	0.189374716070048
GO:0140791	histone H2AXS140 phosphatase activity	13/1670	81/18639	0.160493827160494	1.79128409846973	0.0274298893162017	0.189374716070048
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	13/1670	81/18639	0.160493827160494	1.79128409846973	0.0274298893162017	0.189374716070048
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	13/1670	81/18639	0.160493827160494	1.79128409846973	0.0274298893162017	0.189374716070048
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	13/1670	81/18639	0.160493827160494	1.79128409846973	0.0274298893162017	0.189374716070048
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	13/1670	81/18639	0.160493827160494	1.79128409846973	0.0274298893162017	0.189374716070048
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	13/1670	81/18639	0.160493827160494	1.79128409846973	0.0274298893162017	0.189374716070048
GO:1990439	MAP kinase serine/threonine phosphatase activity	13/1670	81/18639	0.160493827160494	1.79128409846973	0.0274298893162017	0.189374716070048
GO:0060590	ATPase regulator activity	9/1670	49/18639	0.183673469387755	2.04999388977148	0.0282668315164623	0.194056562433241
GO:0016004	phospholipase activator activity	5/1670	20/18639	0.25	2.79026946107784	0.0284662015052972	0.194333509717727
GO:0004601	peroxidase activity	10/1670	57/18639	0.175438596491228	1.95808383233533	0.0287214371474794	0.194986645523443
GO:0009055	electron transfer activity	17/1670	116/18639	0.146551724137931	1.63567520132149	0.0293521357703716	0.196918566785328
GO:0004364	glutathione transferase activity	6/1670	27/18639	0.222222222222222	2.48023952095808	0.0294625421762847	0.196918566785328
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	13/1670	82/18639	0.158536585365854	1.76943917043961	0.0300213541240941	0.196918566785328
GO:0033549	MAP kinase phosphatase activity	13/1670	82/18639	0.158536585365854	1.76943917043961	0.0300213541240941	0.196918566785328
GO:0140272	exogenous protein binding	13/1670	82/18639	0.158536585365854	1.76943917043961	0.0300213541240941	0.196918566785328
GO:0005516	calmodulin binding	27/1670	207/18639	0.130434782608696	1.45579276230148	0.0306461450718451	0.196918566785328
GO:0042056	chemoattractant activity	8/1670	42/18639	0.19047619047619	2.12591958939264	0.0308387802701617	0.196918566785328
GO:0048487	beta-tubulin binding	8/1670	42/18639	0.19047619047619	2.12591958939264	0.0308387802701617	0.196918566785328
GO:0005161	platelet-derived growth factor receptor binding	4/1670	14/18639	0.285714285714286	3.18887938408897	0.030965726822196	0.196918566785328
GO:0019763	immunoglobulin receptor activity	4/1670	14/18639	0.285714285714286	3.18887938408897	0.030965726822196	0.196918566785328
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	4/1670	14/18639	0.285714285714286	3.18887938408897	0.030965726822196	0.196918566785328
GO:0046030	inositol trisphosphate phosphatase activity	4/1670	14/18639	0.285714285714286	3.18887938408897	0.030965726822196	0.196918566785328
GO:0016791	phosphatase activity	34/1670	273/18639	0.124542124542125	1.39002434691057	0.0311008865708415	0.196918566785328
GO:0048020	CCR chemokine receptor binding	9/1670	50/18639	0.18	2.00899401197605	0.0318277857497574	0.200482238073214
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	13/1670	83/18639	0.156626506024096	1.74812062621744	0.0327860035292298	0.20545895544984
GO:0005154	epidermal growth factor receptor binding	7/1670	35/18639	0.2	2.23221556886228	0.0331524949548882	0.206695657320783
GO:0008201	heparin binding	23/1670	172/18639	0.133720930232558	1.49246971173931	0.0339825964994221	0.210795598590324
GO:0019789	SUMO transferase activity	6/1670	28/18639	0.214285714285714	2.39165953806672	0.0347461476055537	0.213365790824054
GO:0097718	disordered domain specific binding	6/1670	28/18639	0.214285714285714	2.39165953806672	0.0347461476055537	0.213365790824054
GO:0008200	ion channel inhibitor activity	8/1670	43/18639	0.186046511627907	2.07647959894165	0.0350177445045207	0.213958418922621
GO:0031593	polyubiquitin modification-dependent protein binding	10/1670	59/18639	0.169491525423729	1.89170810920532	0.0355729923239579	0.215079925193124
GO:0005021	vascular endothelial growth factor receptor activity	9/1670	51/18639	0.176470588235294	1.96960197252554	0.035688225055979	0.215079925193124
GO:0017018	myosin phosphatase activity	13/1670	84/18639	0.154761904761905	1.72730966638152	0.0357293165419019	0.215079925193124
GO:0032934	sterol binding	11/1670	68/18639	0.161764705882353	1.80546847481508	0.0384394184092189	0.230259653412086
GO:0051371	muscle alpha-actinin binding	4/1670	15/18639	0.266666666666667	2.9762874251497	0.0393087739826379	0.230834886990263
GO:0055105	ubiquitin-protein transferase inhibitor activity	4/1670	15/18639	0.266666666666667	2.9762874251497	0.0393087739826379	0.230834886990263
GO:0120283	protein serine/threonine kinase binding	4/1670	15/18639	0.266666666666667	2.9762874251497	0.0393087739826379	0.230834886990263
GO:0004714	transmembrane receptor protein tyrosine kinase activity	10/1670	60/18639	0.166666666666667	1.86017964071856	0.0393922999665689	0.230834886990263
GO:0016248	channel inhibitor activity	8/1670	44/18639	0.181818181818182	2.02928688078389	0.0395631708728249	0.230834886990263
GO:0005080	protein kinase C binding	9/1670	52/18639	0.173076923076923	1.93172501151543	0.0398577423526559	0.230834886990263
GO:0030159	signaling receptor complex adaptor activity	9/1670	52/18639	0.173076923076923	1.93172501151543	0.0398577423526559	0.230834886990263
GO:0004629	phospholipase C activity	6/1670	29/18639	0.206896551724138	2.3091885195127	0.0406032618270987	0.232944534989271
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	6/1670	29/18639	0.206896551724138	2.3091885195127	0.0406032618270987	0.232944534989271
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	5/1670	22/18639	0.227272727272727	2.53660860097986	0.0416804898507836	0.236094342179525
GO:0140035	ubiquitin-like protein reader activity	5/1670	22/18639	0.227272727272727	2.53660860097986	0.0416804898507836	0.236094342179525
GO:0016298	lipase activity	18/1670	130/18639	0.138461538461538	1.54538000921234	0.0418530627472721	0.236094342179525
GO:1901981	phosphatidylinositol phosphate binding	24/1670	185/18639	0.12972972972973	1.44792361223499	0.0419251000433362	0.236094342179525
GO:0002039	p53 binding	11/1670	69/18639	0.159420289855072	1.77930226503515	0.0421749261515788	0.236411742005639
GO:0004867	serine-type endopeptidase inhibitor activity	14/1670	95/18639	0.147368421052632	1.64479041916168	0.0432870235954792	0.241436314571987
GO:0019213	deacetylase activity	7/1670	37/18639	0.189189189189189	2.11155526784269	0.0434736911934935	0.241436314571987
GO:0005525	GTP binding	44/1670	378/18639	0.116402116402116	1.29917308240662	0.0436640143374871	0.241436314571987
GO:0019001	guanyl nucleotide binding	46/1670	400/18639	0.115	1.28352395209581	0.0473620703098361	0.259535649859281
GO:0032561	guanyl ribonucleotide binding	46/1670	400/18639	0.115	1.28352395209581	0.0473620703098361	0.259535649859281
GO:0000062	fatty-acyl-CoA binding	4/1670	16/18639	0.25	2.79026946107784	0.0488046793833826	0.263890788524308
GO:0005149	interleukin-1 receptor binding	4/1670	16/18639	0.25	2.79026946107784	0.0488046793833826	0.263890788524308
GO:0005159	insulin-like growth factor receptor binding	4/1670	16/18639	0.25	2.79026946107784	0.0488046793833826	0.263890788524308
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	9/1670	54/18639	0.166666666666667	1.86017964071856	0.0491576915778605	0.263960704094142
GO:0004602	glutathione peroxidase activity	5/1670	23/18639	0.217391304347826	2.42632127050247	0.0494656311272983	0.263960704094142
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	5/1670	23/18639	0.217391304347826	2.42632127050247	0.0494656311272983	0.263960704094142
GO:0008013	beta-catenin binding	15/1670	106/18639	0.141509433962264	1.57939780815727	0.0507117333317702	0.269433644049666
GO:0003713	transcription coactivator activity	31/1670	256/18639	0.12109375	1.35153677020958	0.0523363911256855	0.274111350094488
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	3/1670	10/18639	0.3	3.34832335329341	0.0533866622933618	0.274111350094488
GO:0004445	inositol-polyphosphate 5-phosphatase activity	3/1670	10/18639	0.3	3.34832335329341	0.0533866622933618	0.274111350094488
GO:0015643	toxic substance binding	3/1670	10/18639	0.3	3.34832335329341	0.0533866622933618	0.274111350094488
GO:0016175	superoxide-generating NAD(P)H oxidase activity	3/1670	10/18639	0.3	3.34832335329341	0.0533866622933618	0.274111350094488
GO:0019911	structural constituent of myelin sheath	3/1670	10/18639	0.3	3.34832335329341	0.0533866622933618	0.274111350094488
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	3/1670	10/18639	0.3	3.34832335329341	0.0533866622933618	0.274111350094488
GO:0070097	delta-catenin binding	3/1670	10/18639	0.3	3.34832335329341	0.0533866622933618	0.274111350094488
GO:0019208	phosphatase regulator activity	16/1670	117/18639	0.136752136752137	1.52630124366651	0.0579322950736043	0.289416401526299
GO:0019957	C-C chemokine binding	5/1670	24/18639	0.208333333333333	2.3252245508982	0.0580468639799055	0.289416401526299
GO:0035035	histone acetyltransferase binding	5/1670	24/18639	0.208333333333333	2.3252245508982	0.0580468639799055	0.289416401526299
GO:0050431	transforming growth factor beta binding	5/1670	24/18639	0.208333333333333	2.3252245508982	0.0580468639799055	0.289416401526299
GO:0050699	WW domain binding	5/1670	24/18639	0.208333333333333	2.3252245508982	0.0580468639799055	0.289416401526299
GO:0060229	lipase activator activity	5/1670	24/18639	0.208333333333333	2.3252245508982	0.0580468639799055	0.289416401526299
GO:0001217	DNA-binding transcription repressor activity	33/1670	278/18639	0.118705035971223	1.3248761469866	0.0583667947795412	0.289416401526299
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	4/1670	17/18639	0.235294117647059	2.62613596336738	0.0594464130794608	0.289416401526299
GO:0008484	sulfuric ester hydrolase activity	4/1670	17/18639	0.235294117647059	2.62613596336738	0.0594464130794608	0.289416401526299
GO:0030169	low-density lipoprotein particle binding	4/1670	17/18639	0.235294117647059	2.62613596336738	0.0594464130794608	0.289416401526299
GO:0046965	nuclear retinoid X receptor binding	4/1670	17/18639	0.235294117647059	2.62613596336738	0.0594464130794608	0.289416401526299
GO:1901567	fatty acid derivative binding	4/1670	17/18639	0.235294117647059	2.62613596336738	0.0594464130794608	0.289416401526299
GO:1990226	histone methyltransferase binding	4/1670	17/18639	0.235294117647059	2.62613596336738	0.0594464130794608	0.289416401526299
GO:0043425	bHLH transcription factor binding	6/1670	32/18639	0.1875	2.09270209580838	0.0617350315905784	0.295832632404124
GO:0004620	phospholipase activity	15/1670	109/18639	0.137614678899083	1.53592814371257	0.0620147716618963	0.295832632404124
GO:0043130	ubiquitin binding	14/1670	100/18639	0.14	1.56255089820359	0.0620547354348853	0.295832632404124
GO:0030331	nuclear estrogen receptor binding	7/1670	40/18639	0.175	1.95318862275449	0.0624806993108908	0.295832632404124
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	7/1670	40/18639	0.175	1.95318862275449	0.0624806993108908	0.295832632404124
GO:0061791	GTPase motor activity	7/1670	40/18639	0.175	1.95318862275449	0.0624806993108908	0.295832632404124
GO:1990606	membrane scission GTPase motor activity	7/1670	40/18639	0.175	1.95318862275449	0.0624806993108908	0.295832632404124
GO:0160215	deacylase activity	10/1670	65/18639	0.153846153846154	1.71708889912483	0.062701024380252	0.295832632404124
GO:0016922	nuclear receptor binding	18/1670	137/18639	0.131386861313869	1.46641898684383	0.064032126326524	0.300950993734663
GO:0043178	alcohol binding	13/1670	92/18639	0.141304347826087	1.57710882582661	0.0662744335377096	0.307305925955343
GO:0017025	TBP-class protein binding	5/1670	25/18639	0.2	2.23221556886228	0.0674232956867028	0.307305925955343
GO:0042974	nuclear retinoic acid receptor binding	5/1670	25/18639	0.2	2.23221556886228	0.0674232956867028	0.307305925955343
GO:0035254	glutamate receptor binding	8/1670	49/18639	0.163265306122449	1.82221679090798	0.0680972401788893	0.307305925955343
GO:0001851	complement component C3b binding	3/1670	11/18639	0.272727272727273	3.04393032117583	0.0686534515432149	0.307305925955343
GO:0002162	dystroglycan binding	3/1670	11/18639	0.272727272727273	3.04393032117583	0.0686534515432149	0.307305925955343
GO:0008199	ferric iron binding	3/1670	11/18639	0.272727272727273	3.04393032117583	0.0686534515432149	0.307305925955343
GO:0016176	superoxide-generating NADPH oxidase activator activity	3/1670	11/18639	0.272727272727273	3.04393032117583	0.0686534515432149	0.307305925955343
GO:0019206	nucleoside kinase activity	3/1670	11/18639	0.272727272727273	3.04393032117583	0.0686534515432149	0.307305925955343
GO:0019215	intermediate filament binding	3/1670	11/18639	0.272727272727273	3.04393032117583	0.0686534515432149	0.307305925955343
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	3/1670	11/18639	0.272727272727273	3.04393032117583	0.0686534515432149	0.307305925955343
GO:0050786	RAGE receptor binding	3/1670	11/18639	0.272727272727273	3.04393032117583	0.0686534515432149	0.307305925955343
GO:0140031	phosphorylation-dependent protein binding	3/1670	11/18639	0.272727272727273	3.04393032117583	0.0686534515432149	0.307305925955343
GO:0061650	ubiquitin-like protein conjugating enzyme activity	7/1670	41/18639	0.170731707317073	1.90554987585804	0.0697825555088748	0.310991565984703
GO:0071889	14-3-3 protein binding	6/1670	33/18639	0.181818181818182	2.02928688078389	0.0699858270423842	0.310991565984703
GO:0051219	phosphoprotein binding	13/1670	93/18639	0.139784946236559	1.56015066640912	0.0710247102408252	0.311905444105431
GO:0008409	5'-3' exonuclease activity	4/1670	18/18639	0.222222222222222	2.48023952095808	0.0712124540960846	0.311905444105431
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	4/1670	18/18639	0.222222222222222	2.48023952095808	0.0712124540960846	0.311905444105431
GO:0017075	syntaxin-1 binding	4/1670	18/18639	0.222222222222222	2.48023952095808	0.0712124540960846	0.311905444105431
GO:0005201	extracellular matrix structural constituent	21/1670	168/18639	0.125	1.39513473053892	0.0744700019407677	0.325008365612922
GO:0005200	structural constituent of cytoskeleton	15/1670	112/18639	0.133928571428571	1.4947872112917	0.0749085532947223	0.325758904363526
GO:0004435	phosphatidylinositol phospholipase C activity	5/1670	26/18639	0.192307692307692	2.14636112390603	0.0775872494055184	0.331509156550851
GO:0005160	transforming growth factor beta receptor binding	5/1670	26/18639	0.192307692307692	2.14636112390603	0.0775872494055184	0.331509156550851
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/1670	26/18639	0.192307692307692	2.14636112390603	0.0775872494055184	0.331509156550851
GO:0008198	ferrous iron binding	5/1670	26/18639	0.192307692307692	2.14636112390603	0.0775872494055184	0.331509156550851
GO:0050750	low-density lipoprotein particle receptor binding	5/1670	26/18639	0.192307692307692	2.14636112390603	0.0775872494055184	0.331509156550851
GO:0051427	hormone receptor binding	6/1670	34/18639	0.176470588235294	1.96960197252554	0.0788403137401625	0.33568941947902
GO:0005010	insulin-like growth factor receptor activity	8/1670	51/18639	0.156862745098039	1.75075730891159	0.0823205881791017	0.347693710730426
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	4/1670	19/18639	0.210526315789474	2.3497005988024	0.0840684699128627	0.347693710730426
GO:0008381	mechanosensitive monoatomic ion channel activity	4/1670	19/18639	0.210526315789474	2.3497005988024	0.0840684699128627	0.347693710730426
GO:0120227	acyl-CoA binding	4/1670	19/18639	0.210526315789474	2.3497005988024	0.0840684699128627	0.347693710730426
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	31/1670	268/18639	0.115671641791045	1.29102019840915	0.0846015850337704	0.347693710730426
GO:0005165	neurotrophin receptor binding	3/1670	12/18639	0.25	2.79026946107784	0.0856430498607677	0.347693710730426
GO:0008603	cAMP-dependent protein kinase regulator activity	3/1670	12/18639	0.25	2.79026946107784	0.0856430498607677	0.347693710730426
GO:0016208	AMP binding	3/1670	12/18639	0.25	2.79026946107784	0.0856430498607677	0.347693710730426
GO:0070410	co-SMAD binding	3/1670	12/18639	0.25	2.79026946107784	0.0856430498607677	0.347693710730426
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	3/1670	12/18639	0.25	2.79026946107784	0.0856430498607677	0.347693710730426
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	3/1670	12/18639	0.25	2.79026946107784	0.0856430498607677	0.347693710730426
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	3/1670	12/18639	0.25	2.79026946107784	0.0856430498607677	0.347693710730426
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	3/1670	12/18639	0.25	2.79026946107784	0.0856430498607677	0.347693710730426
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	3/1670	12/18639	0.25	2.79026946107784	0.0856430498607677	0.347693710730426
GO:0061631	ubiquitin conjugating enzyme activity	6/1670	35/18639	0.171428571428571	1.91332763045338	0.0882929659026331	0.354679221190547
GO:0008083	growth factor activity	20/1670	162/18639	0.123456790123457	1.37791084497671	0.0883841086463691	0.354679221190547
GO:0001671	ATPase activator activity	5/1670	27/18639	0.185185185185185	2.06686626746507	0.0885246828667077	0.354679221190547
GO:0035255	ionotropic glutamate receptor binding	5/1670	27/18639	0.185185185185185	2.06686626746507	0.0885246828667077	0.354679221190547
GO:0017124	SH3 domain binding	15/1670	115/18639	0.130434782608696	1.45579276230148	0.0894436281529918	0.35718991373515
GO:0019905	syntaxin binding	9/1670	61/18639	0.147540983606557	1.64671640325906	0.0923745752140334	0.367692934565306
GO:0033293	monocarboxylic acid binding	11/1670	79/18639	0.139240506329114	1.55407413022057	0.0936014375836683	0.371366742620918
GO:0019205	nucleobase-containing compound kinase activity	7/1670	44/18639	0.159090909090909	1.7756260206859	0.0946017531574893	0.374120849056479
GO:0019888	protein phosphatase regulator activity	14/1670	107/18639	0.130841121495327	1.46032794224635	0.0964600858405915	0.380239435152267
GO:0052745	inositol phosphate phosphatase activity	4/1670	20/18639	0.2	2.23221556886228	0.0979690370147541	0.384479022587365
GO:0038064	collagen receptor activity	8/1670	53/18639	0.150943396226415	1.68469099536776	0.0981648568308167	0.384479022587365
GO:0003735	structural constituent of ribosome	21/1670	175/18639	0.12	1.33932934131737	0.103153499068559	0.40170267276652
GO:0046915	transition metal ion transmembrane transporter activity	7/1670	45/18639	0.155555555555556	1.73616766467066	0.103833709861622	0.40170267276652
GO:0035673	oligopeptide transmembrane transporter activity	3/1670	13/18639	0.230769230769231	2.57563334868724	0.104206012493442	0.40170267276652
GO:0045159	myosin II binding	3/1670	13/18639	0.230769230769231	2.57563334868724	0.104206012493442	0.40170267276652
GO:0070123	transforming growth factor beta receptor activity, type III	3/1670	13/18639	0.230769230769231	2.57563334868724	0.104206012493442	0.40170267276652
GO:0022804	active transmembrane transporter activity	49/1670	457/18639	0.107221006564551	1.19670200081238	0.107089368323054	0.411519522298025
GO:0003785	actin monomer binding	5/1670	29/18639	0.172413793103448	1.92432376626058	0.112634920244284	0.429639017799811
GO:0051861	glycolipid binding	5/1670	29/18639	0.172413793103448	1.92432376626058	0.112634920244284	0.429639017799811
GO:0005123	death receptor binding	4/1670	21/18639	0.19047619047619	2.12591958939264	0.112859349192913	0.429639017799811
GO:0004180	carboxypeptidase activity	7/1670	46/18639	0.152173913043478	1.69842488935173	0.113533256797215	0.430862235422969
GO:0008374	O-acyltransferase activity	8/1670	55/18639	0.145454545454545	1.62342950462711	0.115604506637771	0.437364418301412
GO:0004536	DNA nuclease activity	9/1670	64/18639	0.140625	1.56952657185629	0.116082138674184	0.437815967468681
GO:0042887	amide transmembrane transporter activity	6/1670	38/18639	0.157894736842105	1.7622754491018	0.120132040820021	0.451696473483279
GO:0005313	L-glutamate transmembrane transporter activity	3/1670	14/18639	0.214285714285714	2.39165953806672	0.124180635858328	0.459750971870389
GO:0008191	metalloendopeptidase inhibitor activity	3/1670	14/18639	0.214285714285714	2.39165953806672	0.124180635858328	0.459750971870389
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/1670	14/18639	0.214285714285714	2.39165953806672	0.124180635858328	0.459750971870389
GO:0042043	neurexin family protein binding	3/1670	14/18639	0.214285714285714	2.39165953806672	0.124180635858328	0.459750971870389
GO:0071933	Arp2/3 complex binding	3/1670	14/18639	0.214285714285714	2.39165953806672	0.124180635858328	0.459750971870389
GO:0120013	lipid transfer activity	9/1670	65/18639	0.138461538461538	1.54538000921234	0.124661246328565	0.459750971870389
GO:0170055	lipid transmembrane transporter activity	8/1670	56/18639	0.142857142857143	1.59443969204448	0.124907792684917	0.459750971870389
GO:0035925	mRNA 3'-UTR AU-rich region binding	5/1670	30/18639	0.166666666666667	1.86017964071856	0.125752345842127	0.461469569426663
GO:0008093	cytoskeletal anchor activity	4/1670	22/18639	0.181818181818182	2.02928688078389	0.128676873491164	0.470787842533539
GO:0051117	ATPase binding	11/1670	84/18639	0.130952380952381	1.46156971770744	0.129320908768718	0.471731792583205
GO:0038187	pattern recognition receptor activity	7/1670	48/18639	0.145833333333333	1.62765718562874	0.13429176522829	0.485585086002578
GO:0016411	acylglycerol O-acyltransferase activity	5/1670	31/18639	0.161290322580645	1.80017384585667	0.139533621610045	0.485585086002578
GO:0070325	lipoprotein particle receptor binding	5/1670	31/18639	0.161290322580645	1.80017384585667	0.139533621610045	0.485585086002578
GO:0003774	cytoskeletal motor activity	18/1670	153/18639	0.117647058823529	1.31306798168369	0.141314111117905	0.485585086002578
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	9/1670	67/18639	0.134328358208955	1.49924926266869	0.142800055047942	0.485585086002578
GO:0140030	modification-dependent protein binding	20/1670	173/18639	0.115606936416185	1.2902980166834	0.142983558164543	0.485585086002578
GO:0051087	protein-folding chaperone binding	16/1670	134/18639	0.119402985074627	1.33266601126106	0.144886488251819	0.485585086002578
GO:0005004	GPI-linked ephrin receptor activity	7/1670	49/18639	0.142857142857143	1.59443969204448	0.145324186069857	0.485585086002578
GO:0005008	hepatocyte growth factor receptor activity	7/1670	49/18639	0.142857142857143	1.59443969204448	0.145324186069857	0.485585086002578
GO:0005009	insulin receptor activity	7/1670	49/18639	0.142857142857143	1.59443969204448	0.145324186069857	0.485585086002578
GO:0005011	macrophage colony-stimulating factor receptor activity	7/1670	49/18639	0.142857142857143	1.59443969204448	0.145324186069857	0.485585086002578
GO:0005018	platelet-derived growth factor alpha-receptor activity	7/1670	49/18639	0.142857142857143	1.59443969204448	0.145324186069857	0.485585086002578
GO:0005020	stem cell factor receptor activity	7/1670	49/18639	0.142857142857143	1.59443969204448	0.145324186069857	0.485585086002578
GO:0008288	boss receptor activity	7/1670	49/18639	0.142857142857143	1.59443969204448	0.145324186069857	0.485585086002578
GO:0036332	placental growth factor receptor activity	7/1670	49/18639	0.142857142857143	1.59443969204448	0.145324186069857	0.485585086002578
GO:0038062	protein tyrosine kinase collagen receptor activity	7/1670	49/18639	0.142857142857143	1.59443969204448	0.145324186069857	0.485585086002578
GO:0060175	brain-derived neurotrophic factor receptor activity	7/1670	49/18639	0.142857142857143	1.59443969204448	0.145324186069857	0.485585086002578
GO:0005158	insulin receptor binding	4/1670	23/18639	0.173913043478261	1.94105701640198	0.145352924515135	0.485585086002578
GO:0016493	C-C chemokine receptor activity	4/1670	23/18639	0.173913043478261	1.94105701640198	0.145352924515135	0.485585086002578
GO:0042171	lysophosphatidic acid acyltransferase activity	4/1670	23/18639	0.173913043478261	1.94105701640198	0.145352924515135	0.485585086002578
GO:0043274	phospholipase binding	4/1670	23/18639	0.173913043478261	1.94105701640198	0.145352924515135	0.485585086002578
GO:0071617	lysophospholipid acyltransferase activity	4/1670	23/18639	0.173913043478261	1.94105701640198	0.145352924515135	0.485585086002578
GO:0000774	adenyl-nucleotide exchange factor activity	3/1670	15/18639	0.2	2.23221556886228	0.14539860132725	0.485585086002578
GO:0005402	carbohydrate:monoatomic cation symporter activity	3/1670	15/18639	0.2	2.23221556886228	0.14539860132725	0.485585086002578
GO:0015929	hexosaminidase activity	3/1670	15/18639	0.2	2.23221556886228	0.14539860132725	0.485585086002578
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	3/1670	15/18639	0.2	2.23221556886228	0.14539860132725	0.485585086002578
GO:0031005	filamin binding	3/1670	15/18639	0.2	2.23221556886228	0.14539860132725	0.485585086002578
GO:0031386	protein tag activity	3/1670	15/18639	0.2	2.23221556886228	0.14539860132725	0.485585086002578
GO:0050700	CARD domain binding	3/1670	15/18639	0.2	2.23221556886228	0.14539860132725	0.485585086002578
GO:0141047	molecular tag activity	3/1670	15/18639	0.2	2.23221556886228	0.14539860132725	0.485585086002578
GO:0050660	flavin adenine dinucleotide binding	11/1670	86/18639	0.127906976744186	1.42757972427239	0.145437104318284	0.485585086002578
GO:0005006	epidermal growth factor receptor activity	7/1670	50/18639	0.14	1.56255089820359	0.156771380224848	0.51243948951371
GO:0005007	fibroblast growth factor receptor activity	7/1670	50/18639	0.14	1.56255089820359	0.156771380224848	0.51243948951371
GO:0005017	platelet-derived growth factor receptor activity	7/1670	50/18639	0.14	1.56255089820359	0.156771380224848	0.51243948951371
GO:0005019	platelet-derived growth factor beta-receptor activity	7/1670	50/18639	0.14	1.56255089820359	0.156771380224848	0.51243948951371
GO:0001530	lipopolysaccharide binding	6/1670	41/18639	0.146341463414634	1.63332846502118	0.156834999245603	0.51243948951371
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	6/1670	41/18639	0.146341463414634	1.63332846502118	0.156834999245603	0.51243948951371
GO:0008137	NADH dehydrogenase (ubiquinone) activity	6/1670	41/18639	0.146341463414634	1.63332846502118	0.156834999245603	0.51243948951371
GO:0042287	MHC protein binding	6/1670	41/18639	0.146341463414634	1.63332846502118	0.156834999245603	0.51243948951371
GO:0016651	oxidoreductase activity, acting on NAD(P)H	11/1670	88/18639	0.125	1.39513473053892	0.16254778094712	0.526346230032554
GO:0001091	RNA polymerase II general transcription initiation factor binding	4/1670	24/18639	0.166666666666667	1.86017964071856	0.162814136622181	0.526346230032554
GO:0004622	lysophospholipase activity	4/1670	24/18639	0.166666666666667	1.86017964071856	0.162814136622181	0.526346230032554
GO:0015295	solute:proton symporter activity	4/1670	24/18639	0.166666666666667	1.86017964071856	0.162814136622181	0.526346230032554
GO:0098531	ligand-modulated transcription factor activity	8/1670	60/18639	0.133333333333333	1.48814371257485	0.165797039336958	0.531052931530512
GO:0008234	cysteine-type peptidase activity	21/1670	187/18639	0.112299465240642	1.25338307342534	0.166583134615278	0.531052931530512
GO:0005024	transforming growth factor beta receptor activity	3/1670	16/18639	0.1875	2.09270209580838	0.16768950639122	0.531052931530512
GO:0005521	lamin binding	3/1670	16/18639	0.1875	2.09270209580838	0.16768950639122	0.531052931530512
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/1670	16/18639	0.1875	2.09270209580838	0.16768950639122	0.531052931530512
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/1670	16/18639	0.1875	2.09270209580838	0.16768950639122	0.531052931530512
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	3/1670	16/18639	0.1875	2.09270209580838	0.16768950639122	0.531052931530512
GO:0005496	steroid binding	13/1670	108/18639	0.12037037037037	1.3434630738523	0.168368573982377	0.531052931530512
GO:0005030	neurotrophin receptor activity	7/1670	51/18639	0.137254901960784	1.53191264529764	0.168615824413943	0.531052931530512
GO:0016830	carbon-carbon lyase activity	7/1670	51/18639	0.137254901960784	1.53191264529764	0.168615824413943	0.531052931530512
GO:0008307	structural constituent of muscle	6/1670	42/18639	0.142857142857143	1.59443969204448	0.170045614027101	0.534179281082565
GO:0008028	monocarboxylic acid transmembrane transporter activity	9/1670	70/18639	0.128571428571429	1.43499572284003	0.172339323567523	0.539996547178239
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	8/1670	61/18639	0.131147540983607	1.46374791400805	0.176879675430985	0.552805532932643
GO:0004518	nuclease activity	23/1670	209/18639	0.110047846889952	1.22825258573762	0.177386461867098	0.552975143881616
GO:0001848	complement binding	4/1670	25/18639	0.16	1.78577245508982	0.180983820609892	0.561325453769765
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	4/1670	25/18639	0.16	1.78577245508982	0.180983820609892	0.561325453769765
GO:0016831	carboxy-lyase activity	5/1670	34/18639	0.147058823529412	1.64133497710461	0.184465895411492	0.570676770108465
GO:0032182	ubiquitin-like protein binding	14/1670	120/18639	0.116666666666667	1.30212574850299	0.186058544336686	0.574150356513714
GO:0030971	receptor tyrosine kinase binding	10/1670	81/18639	0.123456790123457	1.37791084497671	0.186982264991622	0.575547425238696
GO:0004550	nucleoside diphosphate kinase activity	3/1670	17/18639	0.176470588235294	1.96960197252554	0.190884454958025	0.578810927937238
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/1670	17/18639	0.176470588235294	1.96960197252554	0.190884454958025	0.578810927937238
GO:0015278	intracellularly gated calcium channel activity	3/1670	17/18639	0.176470588235294	1.96960197252554	0.190884454958025	0.578810927937238
GO:0016805	dipeptidase activity	3/1670	17/18639	0.176470588235294	1.96960197252554	0.190884454958025	0.578810927937238
GO:0019198	transmembrane receptor protein phosphatase activity	3/1670	17/18639	0.176470588235294	1.96960197252554	0.190884454958025	0.578810927937238
GO:0045236	CXCR chemokine receptor binding	3/1670	17/18639	0.176470588235294	1.96960197252554	0.190884454958025	0.578810927937238
GO:0004864	protein phosphatase inhibitor activity	7/1670	53/18639	0.132075471698113	1.47410462094679	0.193419339132727	0.580733249189662
GO:0005003	ephrin receptor activity	7/1670	53/18639	0.132075471698113	1.47410462094679	0.193419339132727	0.580733249189662
GO:0005005	transmembrane-ephrin receptor activity	7/1670	53/18639	0.132075471698113	1.47410462094679	0.193419339132727	0.580733249189662
GO:1901505	carbohydrate derivative transmembrane transporter activity	7/1670	53/18639	0.132075471698113	1.47410462094679	0.193419339132727	0.580733249189662
GO:0004540	RNA nuclease activity	14/1670	121/18639	0.115702479338843	1.29136437868066	0.194241393183602	0.581515840077697
GO:0031072	heat shock protein binding	15/1670	131/18639	0.114503816793893	1.27798601270741	0.194631733708493	0.581515840077697
GO:0003954	NADH dehydrogenase activity	6/1670	44/18639	0.136363636363636	1.52196516058791	0.197767759715997	0.585455796089306
GO:0001637	G protein-coupled chemoattractant receptor activity	4/1670	26/18639	0.153846153846154	1.71708889912483	0.199783197192505	0.585455796089306
GO:0004529	DNA exonuclease activity	4/1670	26/18639	0.153846153846154	1.71708889912483	0.199783197192505	0.585455796089306
GO:0004950	chemokine receptor activity	4/1670	26/18639	0.153846153846154	1.71708889912483	0.199783197192505	0.585455796089306
GO:0005112	Notch binding	4/1670	26/18639	0.153846153846154	1.71708889912483	0.199783197192505	0.585455796089306
GO:0008157	protein phosphatase 1 binding	4/1670	26/18639	0.153846153846154	1.71708889912483	0.199783197192505	0.585455796089306
GO:0050681	nuclear androgen receptor binding	4/1670	26/18639	0.153846153846154	1.71708889912483	0.199783197192505	0.585455796089306
GO:0070412	R-SMAD binding	4/1670	26/18639	0.153846153846154	1.71708889912483	0.199783197192505	0.585455796089306
GO:0005343	organic acid:sodium symporter activity	5/1670	35/18639	0.142857142857143	1.59443969204448	0.200494716996303	0.586135273132731
GO:0008238	exopeptidase activity	12/1670	102/18639	0.117647058823529	1.31306798168369	0.201169605928266	0.586704674091507
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	7/1670	54/18639	0.12962962962963	1.44680638722555	0.206336796138763	0.598915831072608
GO:0051287	NAD binding	7/1670	54/18639	0.12962962962963	1.44680638722555	0.206336796138763	0.598915831072608
GO:0008135	translation factor activity, RNA binding	10/1670	83/18639	0.120481927710843	1.34470817401342	0.207419794124216	0.600632673980549
GO:0003746	translation elongation factor activity	3/1670	18/18639	0.166666666666667	1.86017964071856	0.214818855130413	0.607994605517064
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	3/1670	18/18639	0.166666666666667	1.86017964071856	0.214818855130413	0.607994605517064
GO:0008525	phosphatidylcholine transporter activity	3/1670	18/18639	0.166666666666667	1.86017964071856	0.214818855130413	0.607994605517064
GO:0015172	acidic amino acid transmembrane transporter activity	3/1670	18/18639	0.166666666666667	1.86017964071856	0.214818855130413	0.607994605517064
GO:0016854	racemase and epimerase activity	3/1670	18/18639	0.166666666666667	1.86017964071856	0.214818855130413	0.607994605517064
GO:0031690	adrenergic receptor binding	3/1670	18/18639	0.166666666666667	1.86017964071856	0.214818855130413	0.607994605517064
GO:0050811	GABA receptor binding	3/1670	18/18639	0.166666666666667	1.86017964071856	0.214818855130413	0.607994605517064
GO:0070064	proline-rich region binding	3/1670	18/18639	0.166666666666667	1.86017964071856	0.214818855130413	0.607994605517064
GO:0004869	cysteine-type endopeptidase inhibitor activity	5/1670	36/18639	0.138888888888889	1.5501497005988	0.216972143475656	0.607994605517064
GO:0055106	ubiquitin-protein transferase regulator activity	5/1670	36/18639	0.138888888888889	1.5501497005988	0.216972143475656	0.607994605517064
GO:0180051	translation factor activity	10/1670	84/18639	0.119047619047619	1.3286997433704	0.217973697550634	0.607994605517064
GO:0005104	fibroblast growth factor receptor binding	4/1670	27/18639	0.148148148148148	1.65349301397206	0.219132504031774	0.607994605517064
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	4/1670	27/18639	0.148148148148148	1.65349301397206	0.219132504031774	0.607994605517064
GO:0001094	TFIID-class transcription factor complex binding	2/1670	10/18639	0.2	2.23221556886228	0.223893267170768	0.607994605517064
GO:0004090	carbonyl reductase (NADPH) activity	2/1670	10/18639	0.2	2.23221556886228	0.223893267170768	0.607994605517064
GO:0004862	cAMP-dependent protein kinase inhibitor activity	2/1670	10/18639	0.2	2.23221556886228	0.223893267170768	0.607994605517064
GO:0004955	prostaglandin receptor activity	2/1670	10/18639	0.2	2.23221556886228	0.223893267170768	0.607994605517064
GO:0005031	tumor necrosis factor receptor activity	2/1670	10/18639	0.2	2.23221556886228	0.223893267170768	0.607994605517064
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/1670	10/18639	0.2	2.23221556886228	0.223893267170768	0.607994605517064
GO:0015279	store-operated calcium channel activity	2/1670	10/18639	0.2	2.23221556886228	0.223893267170768	0.607994605517064
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/1670	10/18639	0.2	2.23221556886228	0.223893267170768	0.607994605517064
GO:0016783	sulfurtransferase activity	2/1670	10/18639	0.2	2.23221556886228	0.223893267170768	0.607994605517064
GO:0035256	G protein-coupled glutamate receptor binding	2/1670	10/18639	0.2	2.23221556886228	0.223893267170768	0.607994605517064
GO:0042975	peroxisome proliferator activated receptor binding	2/1670	10/18639	0.2	2.23221556886228	0.223893267170768	0.607994605517064
GO:0043295	glutathione binding	2/1670	10/18639	0.2	2.23221556886228	0.223893267170768	0.607994605517064
GO:0043422	protein kinase B binding	2/1670	10/18639	0.2	2.23221556886228	0.223893267170768	0.607994605517064
GO:0050308	sugar-phosphatase activity	2/1670	10/18639	0.2	2.23221556886228	0.223893267170768	0.607994605517064
GO:1990763	arrestin family protein binding	2/1670	10/18639	0.2	2.23221556886228	0.223893267170768	0.607994605517064
GO:0030276	clathrin binding	6/1670	46/18639	0.130434782608696	1.45579276230148	0.227022036281896	0.615124009615248
GO:0030246	carbohydrate binding	29/1670	280/18639	0.103571428571429	1.15596877673225	0.231720715346285	0.62646618175478
GO:0019212	phosphatase inhibitor activity	7/1670	56/18639	0.125	1.39513473053892	0.233091559168049	0.628781203760166
GO:0042805	actinin binding	5/1670	37/18639	0.135135135135135	1.50825376274478	0.233850145997866	0.629438058170468
GO:0031406	carboxylic acid binding	20/1670	187/18639	0.106951871657754	1.19369816516699	0.234535389702833	0.629895046630467
GO:0046875	ephrin receptor binding	4/1670	28/18639	0.142857142857143	1.59443969204448	0.238951976571562	0.631271060425743
GO:0046966	nuclear thyroid hormone receptor binding	4/1670	28/18639	0.142857142857143	1.59443969204448	0.238951976571562	0.631271060425743
GO:0051393	alpha-actinin binding	4/1670	28/18639	0.142857142857143	1.59443969204448	0.238951976571562	0.631271060425743
GO:0015245	fatty acid transmembrane transporter activity	3/1670	19/18639	0.157894736842105	1.7622754491018	0.239334552358704	0.631271060425743
GO:0030506	ankyrin binding	3/1670	19/18639	0.157894736842105	1.7622754491018	0.239334552358704	0.631271060425743
GO:0046624	sphingolipid transporter activity	3/1670	19/18639	0.157894736842105	1.7622754491018	0.239334552358704	0.631271060425743
GO:0070003	threonine-type peptidase activity	3/1670	19/18639	0.157894736842105	1.7622754491018	0.239334552358704	0.631271060425743
GO:0097001	ceramide binding	3/1670	19/18639	0.157894736842105	1.7622754491018	0.239334552358704	0.631271060425743
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	10/1670	86/18639	0.116279069767442	1.29779974933853	0.239697031127287	0.631271060425743
GO:0043495	protein-membrane adaptor activity	6/1670	47/18639	0.127659574468085	1.42481844820996	0.242143789797023	0.636343464799919
GO:0005319	lipid transporter activity	19/1670	178/18639	0.106741573033708	1.19135100585346	0.244344500521291	0.640748883341239
GO:0004519	endonuclease activity	14/1670	127/18639	0.110236220472441	1.23035503795558	0.246618218157387	0.643083109694014
GO:0016504	peptidase activator activity	7/1670	57/18639	0.12280701754386	1.37065868263473	0.246881889364747	0.643083109694014
GO:0043177	organic acid binding	20/1670	189/18639	0.105820105820106	1.18106643855147	0.24936310654709	0.643083109694014
GO:0016500	protein-hormone receptor activity	8/1670	67/18639	0.119402985074627	1.33266601126106	0.249456165213137	0.643083109694014
GO:0000146	microfilament motor activity	5/1670	38/18639	0.131578947368421	1.4685628742515	0.251080161933904	0.643083109694014
GO:0043531	ADP binding	5/1670	38/18639	0.131578947368421	1.4685628742515	0.251080161933904	0.643083109694014
GO:0140693	molecular condensate scaffold activity	6/1670	48/18639	0.125	1.39513473053892	0.257551221878271	0.643083109694014
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0003953	NAD+ nucleosidase activity	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0004143	ATP-dependent diacylglycerol kinase activity	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0004954	prostanoid receptor activity	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0005114	type II transforming growth factor beta receptor binding	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0008526	phosphatidylinositol transfer activity	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0010854	adenylate cyclase regulator activity	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0015217	ADP transmembrane transporter activity	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0019107	myristoyltransferase activity	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0019203	carbohydrate phosphatase activity	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0045294	alpha-catenin binding	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0047676	arachidonate-CoA ligase activity	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0048185	activin binding	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0048407	platelet-derived growth factor binding	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0070697	activin receptor binding	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:1900750	oligopeptide binding	2/1670	11/18639	0.181818181818182	2.02928688078389	0.258391003976891	0.643083109694014
GO:0004181	metallocarboxypeptidase activity	4/1670	29/18639	0.137931034482759	1.53945901300847	0.259162705583926	0.643692736226743
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	7/1670	58/18639	0.120689655172414	1.34702663638241	0.26091524655216	0.645821293163713
GO:0042626	ATPase-coupled transmembrane transporter activity	11/1670	98/18639	0.112244897959184	1.25277404374924	0.261076692981076	0.645821293163713
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/1670	20/18639	0.15	1.67416167664671	0.264281408007636	0.649802576630446
GO:0030742	GTP-dependent protein binding	3/1670	20/18639	0.15	1.67416167664671	0.264281408007636	0.649802576630446
GO:0042288	MHC class I protein binding	3/1670	20/18639	0.15	1.67416167664671	0.264281408007636	0.649802576630446
GO:0004713	protein tyrosine kinase activity	15/1670	140/18639	0.107142857142857	1.19582976903336	0.271730664061643	0.666776850368128
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	14/1670	130/18639	0.107692307692308	1.20196222938738	0.274651836751245	0.672507976850445
GO:0004879	nuclear receptor activity	7/1670	59/18639	0.11864406779661	1.32419567644372	0.27516692997154	0.672507976850445
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	4/1670	30/18639	0.133333333333333	1.48814371257485	0.279687376313433	0.675421522350458
GO:0031624	ubiquitin conjugating enzyme binding	4/1670	30/18639	0.133333333333333	1.48814371257485	0.279687376313433	0.675421522350458
GO:0033612	receptor serine/threonine kinase binding	4/1670	30/18639	0.133333333333333	1.48814371257485	0.279687376313433	0.675421522350458
GO:0051721	protein phosphatase 2A binding	4/1670	30/18639	0.133333333333333	1.48814371257485	0.279687376313433	0.675421522350458
GO:0051082	unfolded protein binding	13/1670	121/18639	0.107438016528926	1.19912406591775	0.287535179745995	0.675421522350458
GO:0001846	opsonin binding	3/1670	21/18639	0.142857142857143	1.59443969204448	0.28951841781009	0.675421522350458
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	3/1670	21/18639	0.142857142857143	1.59443969204448	0.28951841781009	0.675421522350458
GO:0061891	calcium ion sensor activity	3/1670	21/18639	0.142857142857143	1.59443969204448	0.28951841781009	0.675421522350458
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	7/1670	60/18639	0.116666666666667	1.30212574850299	0.289612009866674	0.675421522350458
GO:1902936	phosphatidylinositol bisphosphate binding	12/1670	111/18639	0.108108108108108	1.20660301019582	0.290802208601904	0.675421522350458
GO:0003995	acyl-CoA dehydrogenase activity	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0004126	cytidine deaminase activity	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0004300	enoyl-CoA hydratase activity	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0005025	transforming growth factor beta receptor activity, type I	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0005026	transforming growth factor beta receptor activity, type II	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0005095	GTPase inhibitor activity	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0005247	voltage-gated chloride channel activity	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0008504	monoamine transmembrane transporter activity	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0015132	prostaglandin transmembrane transporter activity	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0016361	activin receptor activity, type I	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0016362	activin receptor activity, type II	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0016840	carbon-nitrogen lyase activity	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0017002	activin receptor activity	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0035497	cAMP response element binding	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0045295	gamma-catenin binding	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0070008	serine-type exopeptidase activity	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0070679	inositol 1,4,5 trisphosphate binding	2/1670	12/18639	0.166666666666667	1.86017964071856	0.292940594800117	0.675421522350458
GO:0001727	lipid kinase activity	5/1670	41/18639	0.121951219512195	1.36110705418431	0.304397169639775	0.697001368845293
GO:0042169	SH2 domain binding	5/1670	41/18639	0.121951219512195	1.36110705418431	0.304397169639775	0.697001368845293
GO:0003743	translation initiation factor activity	6/1670	51/18639	0.117647058823529	1.31306798168369	0.305151990451908	0.697001368845293
GO:0016597	amino acid binding	6/1670	51/18639	0.117647058823529	1.31306798168369	0.305151990451908	0.697001368845293
GO:0030544	Hsp70 protein binding	6/1670	51/18639	0.117647058823529	1.31306798168369	0.305151990451908	0.697001368845293
GO:0052689	carboxylic ester hydrolase activity	10/1670	92/18639	0.108695652173913	1.21316063525124	0.308928256406963	0.70431031591289
GO:0004407	histone deacetylase activity	3/1670	22/18639	0.136363636363636	1.52196516058791	0.314914451123605	0.712639739394529
GO:0033558	protein lysine deacetylase activity	3/1670	22/18639	0.136363636363636	1.52196516058791	0.314914451123605	0.712639739394529
GO:0070034	telomerase RNA binding	3/1670	22/18639	0.136363636363636	1.52196516058791	0.314914451123605	0.712639739394529
GO:0140784	metal ion sensor activity	3/1670	22/18639	0.136363636363636	1.52196516058791	0.314914451123605	0.712639739394529
GO:0051213	dioxygenase activity	10/1670	93/18639	0.10752688172043	1.20011589723778	0.32092633036401	0.723158769432957
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/1670	32/18639	0.125	1.39513473053892	0.321380913760008	0.723158769432957
GO:0051059	NF-kappaB binding	4/1670	32/18639	0.125	1.39513473053892	0.321380913760008	0.723158769432957
GO:0004520	DNA endonuclease activity	5/1670	42/18639	0.119047619047619	1.3286997433704	0.322552785263109	0.723158769432957
GO:0004465	lipoprotein lipase activity	2/1670	13/18639	0.153846153846154	1.71708889912483	0.32725597340133	0.723158769432957
GO:0004535	poly(A)-specific ribonuclease activity	2/1670	13/18639	0.153846153846154	1.71708889912483	0.32725597340133	0.723158769432957
GO:0005035	death receptor activity	2/1670	13/18639	0.153846153846154	1.71708889912483	0.32725597340133	0.723158769432957
GO:0005338	nucleotide-sugar transmembrane transporter activity	2/1670	13/18639	0.153846153846154	1.71708889912483	0.32725597340133	0.723158769432957
GO:0005542	folic acid binding	2/1670	13/18639	0.153846153846154	1.71708889912483	0.32725597340133	0.723158769432957
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/1670	13/18639	0.153846153846154	1.71708889912483	0.32725597340133	0.723158769432957
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/1670	13/18639	0.153846153846154	1.71708889912483	0.32725597340133	0.723158769432957
GO:0071714	icosanoid transmembrane transporter activity	2/1670	13/18639	0.153846153846154	1.71708889912483	0.32725597340133	0.723158769432957
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/1670	13/18639	0.153846153846154	1.71708889912483	0.32725597340133	0.723158769432957
GO:0004521	RNA endonuclease activity	8/1670	73/18639	0.10958904109589	1.22313181855467	0.329668574155154	0.727175085952343
GO:0016860	intramolecular oxidoreductase activity	6/1670	53/18639	0.113207547169811	1.26351824652582	0.337700502542692	0.741987859033903
GO:0140296	general transcription initiation factor binding	6/1670	53/18639	0.113207547169811	1.26351824652582	0.337700502542692	0.741987859033903
GO:0004527	exonuclease activity	9/1670	84/18639	0.107142857142857	1.19582976903336	0.338205595320691	0.741987859033903
GO:0005283	amino acid:sodium symporter activity	3/1670	23/18639	0.130434782608696	1.45579276230148	0.340348680114877	0.743724327231651
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	3/1670	23/18639	0.130434782608696	1.45579276230148	0.340348680114877	0.743724327231651
GO:0048156	tau protein binding	5/1670	43/18639	0.116279069767442	1.29779974933853	0.340822932282917	0.743724327231651
GO:0140416	transcription regulator inhibitor activity	4/1670	33/18639	0.121212121212121	1.35285792052259	0.342408250604658	0.745851839998025
GO:0044183	protein folding chaperone	8/1670	75/18639	0.106666666666667	1.19051497005988	0.357388094047429	0.765237236264855
GO:0001046	core promoter sequence-specific DNA binding	5/1670	44/18639	0.113636363636364	1.26830430048993	0.359163339022266	0.765237236264855
GO:0030547	signaling receptor inhibitor activity	5/1670	44/18639	0.113636363636364	1.26830430048993	0.359163339022266	0.765237236264855
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	13/1670	128/18639	0.1015625	1.13354696856287	0.360257124659064	0.765237236264855
GO:0004065	arylsulfatase activity	2/1670	14/18639	0.142857142857143	1.59443969204448	0.361101862991831	0.765237236264855
GO:0005347	ATP transmembrane transporter activity	2/1670	14/18639	0.142857142857143	1.59443969204448	0.361101862991831	0.765237236264855
GO:0005545	1-phosphatidylinositol binding	2/1670	14/18639	0.142857142857143	1.59443969204448	0.361101862991831	0.765237236264855
GO:0008474	palmitoyl-(protein) hydrolase activity	2/1670	14/18639	0.142857142857143	1.59443969204448	0.361101862991831	0.765237236264855
GO:0032454	histone H3K9 demethylase activity	2/1670	14/18639	0.142857142857143	1.59443969204448	0.361101862991831	0.765237236264855
GO:0061665	SUMO ligase activity	2/1670	14/18639	0.142857142857143	1.59443969204448	0.361101862991831	0.765237236264855
GO:0098599	palmitoyl hydrolase activity	2/1670	14/18639	0.142857142857143	1.59443969204448	0.361101862991831	0.765237236264855
GO:0098821	BMP receptor activity	2/1670	14/18639	0.142857142857143	1.59443969204448	0.361101862991831	0.765237236264855
GO:1901612	cardiolipin binding	2/1670	14/18639	0.142857142857143	1.59443969204448	0.361101862991831	0.765237236264855
GO:0008376	acetylgalactosaminyltransferase activity	4/1670	34/18639	0.117647058823529	1.31306798168369	0.363467231297081	0.765237236264855
GO:0030332	cyclin binding	4/1670	34/18639	0.117647058823529	1.31306798168369	0.363467231297081	0.765237236264855
GO:0052866	phosphatidylinositol phosphate phosphatase activity	4/1670	34/18639	0.117647058823529	1.31306798168369	0.363467231297081	0.765237236264855
GO:0090482	vitamin transmembrane transporter activity	4/1670	34/18639	0.117647058823529	1.31306798168369	0.363467231297081	0.765237236264855
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	3/1670	24/18639	0.125	1.39513473053892	0.36571075775669	0.765237236264855
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	3/1670	24/18639	0.125	1.39513473053892	0.36571075775669	0.765237236264855
GO:0004806	triacylglycerol lipase activity	3/1670	24/18639	0.125	1.39513473053892	0.36571075775669	0.765237236264855
GO:0030215	semaphorin receptor binding	3/1670	24/18639	0.125	1.39513473053892	0.36571075775669	0.765237236264855
GO:0030552	cAMP binding	3/1670	24/18639	0.125	1.39513473053892	0.36571075775669	0.765237236264855
GO:0048027	mRNA 5'-UTR binding	3/1670	24/18639	0.125	1.39513473053892	0.36571075775669	0.765237236264855
GO:0004679	AMP-activated protein kinase activity	24/1670	248/18639	0.0967741935483871	1.080104307514	0.376869439008047	0.787238383705699
GO:0140303	intramembrane lipid transporter activity	5/1670	45/18639	0.111111111111111	1.24011976047904	0.37753136239989	0.787275298383388
GO:0008235	metalloexopeptidase activity	7/1670	66/18639	0.106060606060606	1.18375068045727	0.378950951502503	0.788889374337409
GO:0016798	hydrolase activity, acting on glycosyl bonds	13/1670	130/18639	0.1	1.11610778443114	0.38160699317675	0.793067594663247
GO:0008237	metallopeptidase activity	18/1670	184/18639	0.0978260869565217	1.09184457172611	0.383870955958398	0.795080346153396
GO:0016229	steroid dehydrogenase activity	4/1670	35/18639	0.114285714285714	1.27555175363559	0.384495942819762	0.795080346153396
GO:0046982	protein heterodimerization activity	35/1670	369/18639	0.0948509485094851	1.05863881992113	0.386956190556328	0.795080346153396
GO:0015645	fatty acid ligase activity	3/1670	25/18639	0.12	1.33932934131737	0.390900794640345	0.795080346153396
GO:0120515	fatty acid-CoA ligase activity	3/1670	25/18639	0.12	1.33932934131737	0.390900794640345	0.795080346153396
GO:0019787	ubiquitin-like protein transferase activity	45/1670	479/18639	0.0939457202505219	1.04853549685598	0.391221970937849	0.795080346153396
GO:0004467	long-chain fatty acid-CoA ligase activity	2/1670	15/18639	0.133333333333333	1.48814371257485	0.394286980170997	0.795080346153396
GO:0004559	alpha-mannosidase activity	2/1670	15/18639	0.133333333333333	1.48814371257485	0.394286980170997	0.795080346153396
GO:0004953	icosanoid receptor activity	2/1670	15/18639	0.133333333333333	1.48814371257485	0.394286980170997	0.795080346153396
GO:0010181	FMN binding	2/1670	15/18639	0.133333333333333	1.48814371257485	0.394286980170997	0.795080346153396
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/1670	15/18639	0.133333333333333	1.48814371257485	0.394286980170997	0.795080346153396
GO:0017081	chloride channel regulator activity	2/1670	15/18639	0.133333333333333	1.48814371257485	0.394286980170997	0.795080346153396
GO:0030553	cGMP binding	2/1670	15/18639	0.133333333333333	1.48814371257485	0.394286980170997	0.795080346153396
GO:0047372	monoacylglycerol lipase activity	2/1670	15/18639	0.133333333333333	1.48814371257485	0.394286980170997	0.795080346153396
GO:0048531	beta-1,3-galactosyltransferase activity	2/1670	15/18639	0.133333333333333	1.48814371257485	0.394286980170997	0.795080346153396
GO:0050780	dopamine receptor binding	2/1670	15/18639	0.133333333333333	1.48814371257485	0.394286980170997	0.795080346153396
GO:0141050	histone H3K deacetylase activity	2/1670	15/18639	0.133333333333333	1.48814371257485	0.394286980170997	0.795080346153396
GO:0141051	histone H4K deacetylase activity	2/1670	15/18639	0.133333333333333	1.48814371257485	0.394286980170997	0.795080346153396
GO:0044390	ubiquitin-like protein conjugating enzyme binding	4/1670	36/18639	0.111111111111111	1.24011976047904	0.405436417737775	0.814873852755857
GO:0045505	dynein intermediate chain binding	4/1670	36/18639	0.111111111111111	1.24011976047904	0.405436417737775	0.814873852755857
GO:0005548	phospholipid transporter activity	7/1670	68/18639	0.102941176470588	1.14893448397323	0.409166548327615	0.821020561668877
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	12/1670	122/18639	0.0983606557377049	1.09781093550604	0.411927592635772	0.825205767542482
GO:0004112	cyclic-nucleotide phosphodiesterase activity	3/1670	26/18639	0.115384615384615	1.28781667434362	0.415829176916149	0.828944949741491
GO:0052742	phosphatidylinositol kinase activity	3/1670	26/18639	0.115384615384615	1.28781667434362	0.415829176916149	0.828944949741491
GO:0120014	phospholipid transfer activity	3/1670	26/18639	0.115384615384615	1.28781667434362	0.415829176916149	0.828944949741491
GO:0016755	aminoacyltransferase activity	46/1670	496/18639	0.092741935483871	1.03509996136759	0.425086511078537	0.832869224404745
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/1670	16/18639	0.125	1.39513473053892	0.426658047853822	0.832869224404745
GO:0004708	MAP kinase kinase activity	2/1670	16/18639	0.125	1.39513473053892	0.426658047853822	0.832869224404745
GO:0005324	long-chain fatty acid transmembrane transporter activity	2/1670	16/18639	0.125	1.39513473053892	0.426658047853822	0.832869224404745
GO:0008296	3'-5'-DNA exonuclease activity	2/1670	16/18639	0.125	1.39513473053892	0.426658047853822	0.832869224404745
GO:0015378	sodium:chloride symporter activity	2/1670	16/18639	0.125	1.39513473053892	0.426658047853822	0.832869224404745
GO:0015923	mannosidase activity	2/1670	16/18639	0.125	1.39513473053892	0.426658047853822	0.832869224404745
GO:0016722	oxidoreductase activity, acting on metal ions	2/1670	16/18639	0.125	1.39513473053892	0.426658047853822	0.832869224404745
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/1670	16/18639	0.125	1.39513473053892	0.426658047853822	0.832869224404745
GO:0043023	ribosomal large subunit binding	2/1670	16/18639	0.125	1.39513473053892	0.426658047853822	0.832869224404745
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/1670	16/18639	0.125	1.39513473053892	0.426658047853822	0.832869224404745
GO:0140327	flippase activity	2/1670	16/18639	0.125	1.39513473053892	0.426658047853822	0.832869224404745
GO:0140328	floppase activity	2/1670	16/18639	0.125	1.39513473053892	0.426658047853822	0.832869224404745
GO:0141003	histone H2AX kinase activity	33/1670	354/18639	0.0932203389830508	1.04043946006292	0.4320272844578	0.842005329517436
GO:0005385	zinc ion transmembrane transporter activity	3/1670	27/18639	0.111111111111111	1.24011976047904	0.440416261026696	0.854267731705751
GO:0016405	CoA-ligase activity	3/1670	27/18639	0.111111111111111	1.24011976047904	0.440416261026696	0.854267731705751
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	3/1670	27/18639	0.111111111111111	1.24011976047904	0.440416261026696	0.854267731705751
GO:0044325	transmembrane transporter binding	13/1670	136/18639	0.0955882352941176	1.066867735118	0.446181256093809	0.862622302368295
GO:0005109	frizzled binding	4/1670	38/18639	0.105263157894737	1.1748502994012	0.446841176267701	0.862622302368295
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	4/1670	38/18639	0.105263157894737	1.1748502994012	0.446841176267701	0.862622302368295
GO:0140996	histone H3 kinase activity	33/1670	357/18639	0.092436974789916	1.0316962713229	0.452023318490569	0.865210992086335
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	6/1670	60/18639	0.1	1.11610778443114	0.45277505173772	0.865210992086335
GO:0035401	histone H3Y41 kinase activity	11/1670	115/18639	0.0956521739130435	1.06758135902109	0.456708531797883	0.865210992086335
GO:0140801	histone H2AXY142 kinase activity	11/1670	115/18639	0.0956521739130435	1.06758135902109	0.456708531797883	0.865210992086335
GO:0141108	transporter regulator activity	16/1670	170/18639	0.0941176470588235	1.05045438534695	0.456743369792079	0.865210992086335
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/1670	17/18639	0.117647058823529	1.31306798168369	0.458094526906595	0.865210992086335
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	2/1670	17/18639	0.117647058823529	1.31306798168369	0.458094526906595	0.865210992086335
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/1670	17/18639	0.117647058823529	1.31306798168369	0.458094526906595	0.865210992086335
GO:0017110	nucleoside diphosphate phosphatase activity	2/1670	17/18639	0.117647058823529	1.31306798168369	0.458094526906595	0.865210992086335
GO:0031489	myosin V binding	2/1670	17/18639	0.117647058823529	1.31306798168369	0.458094526906595	0.865210992086335
GO:0038191	neuropilin binding	2/1670	17/18639	0.117647058823529	1.31306798168369	0.458094526906595	0.865210992086335
GO:0048038	quinone binding	2/1670	17/18639	0.117647058823529	1.31306798168369	0.458094526906595	0.865210992086335
GO:0051787	misfolded protein binding	2/1670	17/18639	0.117647058823529	1.31306798168369	0.458094526906595	0.865210992086335
GO:0070492	oligosaccharide binding	2/1670	17/18639	0.117647058823529	1.31306798168369	0.458094526906595	0.865210992086335
GO:0036408	histone H3K14 acetyltransferase activity	3/1670	28/18639	0.107142857142857	1.19582976903336	0.464591975161312	0.870753671237919
GO:0045499	chemorepellent activity	3/1670	28/18639	0.107142857142857	1.19582976903336	0.464591975161312	0.870753671237919
GO:0046625	sphingolipid binding	3/1670	28/18639	0.107142857142857	1.19582976903336	0.464591975161312	0.870753671237919
GO:0051959	dynein light intermediate chain binding	3/1670	28/18639	0.107142857142857	1.19582976903336	0.464591975161312	0.870753671237919
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	3/1670	28/18639	0.107142857142857	1.19582976903336	0.464591975161312	0.870753671237919
GO:0099106	ion channel regulator activity	15/1670	160/18639	0.09375	1.04635104790419	0.466822066021039	0.871649898822995
GO:0016776	phosphotransferase activity, phosphate group as acceptor	4/1670	39/18639	0.102564102564103	1.14472593274988	0.467210052151442	0.871649898822995
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	4/1670	39/18639	0.102564102564103	1.14472593274988	0.467210052151442	0.871649898822995
GO:0015294	solute:monoatomic cation symporter activity	11/1670	116/18639	0.0948275862068965	1.05837807144332	0.468417825187921	0.87257100972506
GO:0035173	histone kinase activity	33/1670	360/18639	0.0916666666666667	1.02309880239521	0.472025625973679	0.877953295190008
GO:0004175	endopeptidase activity	37/1670	405/18639	0.091358024691358	1.01965402528277	0.475863248275659	0.880371093928397
GO:0140767	enzyme-substrate adaptor activity	13/1670	139/18639	0.0935251798561151	1.04384181277732	0.478366131868141	0.880371093928397
GO:0004532	RNA exonuclease activity	4/1670	40/18639	0.1	1.11610778443114	0.487299859834231	0.880371093928397
GO:0015036	disulfide oxidoreductase activity	4/1670	40/18639	0.1	1.11610778443114	0.487299859834231	0.880371093928397
GO:0015144	carbohydrate transmembrane transporter activity	4/1670	40/18639	0.1	1.11610778443114	0.487299859834231	0.880371093928397
GO:0071949	FAD binding	4/1670	40/18639	0.1	1.11610778443114	0.487299859834231	0.880371093928397
GO:0005416	amino acid:monoatomic cation symporter activity	3/1670	29/18639	0.103448275862069	1.15459425975635	0.488295352420241	0.880371093928397
GO:0010484	histone H3 acetyltransferase activity	3/1670	29/18639	0.103448275862069	1.15459425975635	0.488295352420241	0.880371093928397
GO:0035250	UDP-galactosyltransferase activity	3/1670	29/18639	0.103448275862069	1.15459425975635	0.488295352420241	0.880371093928397
GO:0099604	ligand-gated calcium channel activity	3/1670	29/18639	0.103448275862069	1.15459425975635	0.488295352420241	0.880371093928397
GO:0000900	mRNA regulatory element binding translation repressor activity	2/1670	18/18639	0.111111111111111	1.24011976047904	0.488503985878617	0.880371093928397
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/1670	18/18639	0.111111111111111	1.24011976047904	0.488503985878617	0.880371093928397
GO:0008308	voltage-gated monoatomic anion channel activity	2/1670	18/18639	0.111111111111111	1.24011976047904	0.488503985878617	0.880371093928397
GO:0015280	ligand-gated sodium channel activity	2/1670	18/18639	0.111111111111111	1.24011976047904	0.488503985878617	0.880371093928397
GO:0015373	monoatomic anion:sodium symporter activity	2/1670	18/18639	0.111111111111111	1.24011976047904	0.488503985878617	0.880371093928397
GO:0035615	clathrin adaptor activity	2/1670	18/18639	0.111111111111111	1.24011976047904	0.488503985878617	0.880371093928397
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	2/1670	18/18639	0.111111111111111	1.24011976047904	0.488503985878617	0.880371093928397
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	2/1670	18/18639	0.111111111111111	1.24011976047904	0.488503985878617	0.880371093928397
GO:0070628	proteasome binding	2/1670	18/18639	0.111111111111111	1.24011976047904	0.488503985878617	0.880371093928397
GO:1901611	phosphatidylglycerol binding	2/1670	18/18639	0.111111111111111	1.24011976047904	0.488503985878617	0.880371093928397
GO:1990381	ubiquitin-specific protease binding	2/1670	18/18639	0.111111111111111	1.24011976047904	0.488503985878617	0.880371093928397
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	21/1670	229/18639	0.091703056768559	1.02350495515519	0.489175100472489	0.880371093928397
GO:0016407	acetyltransferase activity	9/1670	96/18639	0.09375	1.04635104790419	0.494820902699004	0.889222269262033
GO:0015175	neutral L-amino acid transmembrane transporter activity	4/1670	41/18639	0.0975609756097561	1.08888564334745	0.507073123639037	0.893345680732922
GO:0016877	ligase activity, forming carbon-sulfur bonds	4/1670	41/18639	0.0975609756097561	1.08888564334745	0.507073123639037	0.893345680732922
GO:0017080	sodium channel regulator activity	4/1670	41/18639	0.0975609756097561	1.08888564334745	0.507073123639037	0.893345680732922
GO:0140318	protein transporter activity	4/1670	41/18639	0.0975609756097561	1.08888564334745	0.507073123639037	0.893345680732922
GO:0031210	phosphatidylcholine binding	3/1670	30/18639	0.1	1.11610778443114	0.511474016432109	0.893345680732922
GO:0043995	histone H4K5 acetyltransferase activity	3/1670	30/18639	0.1	1.11610778443114	0.511474016432109	0.893345680732922
GO:0043996	histone H4K8 acetyltransferase activity	3/1670	30/18639	0.1	1.11610778443114	0.511474016432109	0.893345680732922
GO:0043997	histone H4K12 acetyltransferase activity	3/1670	30/18639	0.1	1.11610778443114	0.511474016432109	0.893345680732922
GO:0048019	receptor antagonist activity	3/1670	30/18639	0.1	1.11610778443114	0.511474016432109	0.893345680732922
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	22/1670	243/18639	0.0905349794238683	1.01046795298292	0.512464652473924	0.893345680732922
GO:0003725	double-stranded RNA binding	7/1670	75/18639	0.0933333333333333	1.0417005988024	0.513187246558219	0.893345680732922
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/1670	19/18639	0.105263157894737	1.1748502994012	0.51781803688096	0.893345680732922
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/1670	19/18639	0.105263157894737	1.1748502994012	0.51781803688096	0.893345680732922
GO:0008301	DNA binding, bending	2/1670	19/18639	0.105263157894737	1.1748502994012	0.51781803688096	0.893345680732922
GO:0016918	retinal binding	2/1670	19/18639	0.105263157894737	1.1748502994012	0.51781803688096	0.893345680732922
GO:0042577	lipid phosphatase activity	2/1670	19/18639	0.105263157894737	1.1748502994012	0.51781803688096	0.893345680732922
GO:0050145	nucleoside monophosphate kinase activity	2/1670	19/18639	0.105263157894737	1.1748502994012	0.51781803688096	0.893345680732922
GO:0005246	calcium channel regulator activity	5/1670	53/18639	0.0943396226415094	1.05293187210485	0.520998238820729	0.893345680732922
GO:0034212	protein N-acetyltransferase activity	5/1670	53/18639	0.0943396226415094	1.05293187210485	0.520998238820729	0.893345680732922
GO:0051018	protein kinase A binding	5/1670	53/18639	0.0943396226415094	1.05293187210485	0.520998238820729	0.893345680732922
GO:0046943	carboxylic acid transmembrane transporter activity	17/1670	188/18639	0.0904255319148936	1.00924640081539	0.521455957647101	0.893345680732922
GO:0005179	hormone activity	12/1670	132/18639	0.0909090909090909	1.01464344039194	0.523295231613296	0.893345680732922
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	12/1670	132/18639	0.0909090909090909	1.01464344039194	0.523295231613296	0.893345680732922
GO:0004402	histone acetyltransferase activity	4/1670	42/18639	0.0952380952380952	1.06295979469632	0.526496317152292	0.893345680732922
GO:0019894	kinesin binding	4/1670	42/18639	0.0952380952380952	1.06295979469632	0.526496317152292	0.893345680732922
GO:0016829	lyase activity	18/1670	200/18639	0.09	1.00449700598802	0.528316147690076	0.893345680732922
GO:0004676	3-phosphoinositide-dependent protein kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:0004711	ribosomal protein S6 kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:0035175	histone H3S10 kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:0035979	histone H2AXS139 kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:0044022	histone H3S28 kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:0044023	histone H4S1 kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:0044024	histone H2AS1 kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:0044025	histone H2BS14 kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:0072354	histone H3T3 kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:0072371	histone H2AS121 kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:0072518	Rho-dependent protein serine/threonine kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:0140823	histone H2BS36 kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:0140855	histone H3S57 kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:0140995	histone H2A kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:0140997	histone H4 kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:0140998	histone H2B kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:1990244	histone H2AT120 kinase activity	22/1670	245/18639	0.0897959183673469	1.00221923499939	0.528550676898447	0.893345680732922
GO:0005342	organic acid transmembrane transporter activity	17/1670	189/18639	0.0899470899470899	1.00390647276875	0.530579224071308	0.895535651678367
GO:0019843	rRNA binding	6/1670	65/18639	0.0923076923076923	1.0302533394749	0.532248469897999	0.896497532744934
GO:0016878	acid-thiol ligase activity	3/1670	31/18639	0.0967741935483871	1.080104307514	0.534083636528897	0.896497532744934
GO:0047499	calcium-independent phospholipase A2 activity	3/1670	31/18639	0.0967741935483871	1.080104307514	0.534083636528897	0.896497532744934
GO:0070273	phosphatidylinositol-4-phosphate binding	3/1670	31/18639	0.0967741935483871	1.080104307514	0.534083636528897	0.896497532744934
GO:0004677	DNA-dependent protein kinase activity	22/1670	246/18639	0.0894308943089431	0.998145173068497	0.536544084963682	0.896549292689698
GO:0140857	histone H3T45 kinase activity	22/1670	246/18639	0.0894308943089431	0.998145173068497	0.536544084963682	0.896549292689698
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	11/1670	122/18639	0.0901639344262295	1.00632669088053	0.537456198304005	0.896549292689698
GO:0050661	NADP binding	5/1670	54/18639	0.0925925925925926	1.03343313373253	0.538026531981703	0.896549292689698
GO:0004842	ubiquitin-protein transferase activity	40/1670	449/18639	0.089086859688196	0.994305375885201	0.539963645585697	0.896549292689698
GO:0003724	RNA helicase activity	7/1670	77/18639	0.0909090909090909	1.01464344039194	0.541800632469648	0.896549292689698
GO:0035402	histone H3T11 kinase activity	22/1670	247/18639	0.0890688259109312	0.994104099493321	0.54450049496045	0.896549292689698
GO:0035403	histone H3T6 kinase activity	22/1670	247/18639	0.0890688259109312	0.994104099493321	0.54450049496045	0.896549292689698
GO:0016247	channel regulator activity	15/1670	168/18639	0.0892857142857143	0.996524807527802	0.545241576914932	0.896549292689698
GO:0001614	purinergic nucleotide receptor activity	2/1670	20/18639	0.1	1.11610778443114	0.54598877342244	0.896549292689698
GO:0005326	neurotransmitter transmembrane transporter activity	2/1670	20/18639	0.1	1.11610778443114	0.54598877342244	0.896549292689698
GO:0010851	cyclase regulator activity	2/1670	20/18639	0.1	1.11610778443114	0.54598877342244	0.896549292689698
GO:0016408	C-acyltransferase activity	2/1670	20/18639	0.1	1.11610778443114	0.54598877342244	0.896549292689698
GO:0016502	nucleotide receptor activity	2/1670	20/18639	0.1	1.11610778443114	0.54598877342244	0.896549292689698
GO:0031418	L-ascorbic acid binding	2/1670	20/18639	0.1	1.11610778443114	0.54598877342244	0.896549292689698
GO:0043024	ribosomal small subunit binding	2/1670	20/18639	0.1	1.11610778443114	0.54598877342244	0.896549292689698
GO:0015293	symporter activity	13/1670	146/18639	0.089041095890411	0.99379460257567	0.551823149394816	0.896549292689698
GO:0008378	galactosyltransferase activity	3/1670	32/18639	0.09375	1.04635104790419	0.556087366470506	0.896549292689698
GO:0022884	macromolecule transmembrane transporter activity	3/1670	32/18639	0.09375	1.04635104790419	0.556087366470506	0.896549292689698
GO:0016790	thiolester hydrolase activity	4/1670	44/18639	0.0909090909090909	1.01464344039194	0.564177381463378	0.896549292689698
GO:0043014	alpha-tubulin binding	4/1670	44/18639	0.0909090909090909	1.01464344039194	0.564177381463378	0.896549292689698
GO:0016779	nucleotidyltransferase activity	12/1670	136/18639	0.0882352941176471	0.984800986262769	0.566193577497422	0.896549292689698
GO:0008186	ATP-dependent activity, acting on RNA	7/1670	79/18639	0.0886075949367089	0.988956264685818	0.569694965397696	0.896549292689698
GO:0030170	pyridoxal phosphate binding	5/1670	56/18639	0.0892857142857143	0.996524807527802	0.571207951241035	0.896549292689698
GO:0010314	phosphatidylinositol-5-phosphate binding	2/1670	21/18639	0.0952380952380952	1.06295979469632	0.572985652960582	0.896549292689698
GO:0015125	bile acid transmembrane transporter activity	2/1670	21/18639	0.0952380952380952	1.06295979469632	0.572985652960582	0.896549292689698
GO:0015174	basic amino acid transmembrane transporter activity	2/1670	21/18639	0.0952380952380952	1.06295979469632	0.572985652960582	0.896549292689698
GO:0019200	carbohydrate kinase activity	2/1670	21/18639	0.0952380952380952	1.06295979469632	0.572985652960582	0.896549292689698
GO:0035613	RNA stem-loop binding	2/1670	21/18639	0.0952380952380952	1.06295979469632	0.572985652960582	0.896549292689698
GO:0036122	BMP binding	2/1670	21/18639	0.0952380952380952	1.06295979469632	0.572985652960582	0.896549292689698
GO:0051010	microtubule plus-end binding	2/1670	21/18639	0.0952380952380952	1.06295979469632	0.572985652960582	0.896549292689698
GO:0140312	cargo adaptor activity	2/1670	21/18639	0.0952380952380952	1.06295979469632	0.572985652960582	0.896549292689698
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	8/1670	91/18639	0.0879120879120879	0.981193656642759	0.576058348677255	0.896549292689698
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	3/1670	33/18639	0.0909090909090909	1.01464344039194	0.577455278057091	0.896549292689698
GO:0019239	deaminase activity	3/1670	33/18639	0.0909090909090909	1.01464344039194	0.577455278057091	0.896549292689698
GO:0003777	microtubule motor activity	6/1670	68/18639	0.0882352941176471	0.984800986262769	0.577534500663133	0.896549292689698
GO:0004674	protein serine/threonine kinase activity	38/1670	433/18639	0.0877598152424942	0.979494129523862	0.578954660950745	0.896549292689698
GO:0015932	nucleobase-containing compound transmembrane transporter activity	5/1670	57/18639	0.087719298245614	0.979041916167665	0.587324741395992	0.896549292689698
GO:0070279	vitamin B6 binding	5/1670	57/18639	0.087719298245614	0.979041916167665	0.587324741395992	0.896549292689698
GO:0008080	N-acetyltransferase activity	6/1670	69/18639	0.0869565217391304	0.970528508200989	0.592132770726476	0.896549292689698
GO:0015101	organic cation transmembrane transporter activity	7/1670	81/18639	0.0864197530864197	0.964537591483699	0.596771746838776	0.896549292689698
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	3/1670	34/18639	0.0882352941176471	0.984800986262769	0.598163798711286	0.896549292689698
GO:0008970	phospholipase A1 activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0015377	chloride:monoatomic cation symporter activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0031683	G-protein beta/gamma-subunit complex binding	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0032931	histone H3K56 acetyltransferase activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0043992	histone H3K9 acetyltransferase activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0043993	histone H3K18 acetyltransferase activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0043994	histone H3K23 acetyltransferase activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0043999	histone H2AK5 acetyltransferase activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0044012	histone H2AK9 acetyltransferase activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0044014	histone H2BK5 acetyltransferase activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0044015	histone H2BK12 acetyltransferase activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0044016	histone H3K4 acetyltransferase activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0044017	histone H3K27 acetyltransferase activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0044018	histone H3K36 acetyltransferase activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0046972	histone H4K16 acetyltransferase activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0061133	endopeptidase activator activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0140517	protein-RNA adaptor activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0140908	histone H3K122 acetyltransferase activity	2/1670	22/18639	0.0909090909090909	1.01464344039194	0.598792773144279	0.896549292689698
GO:0008408	3'-5' exonuclease activity	5/1670	58/18639	0.0862068965517241	0.962161883130291	0.603104793430452	0.896549292689698
GO:0003796	lysozyme activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0004382	GDP phosphatase activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0004935	adrenergic receptor activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0005337	nucleoside transmembrane transporter activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0005522	profilin binding	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0008140	cAMP response element binding protein binding	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0008239	dipeptidyl-peptidase activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0016868	intramolecular phosphotransferase activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0030957	Tat protein binding	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0031434	mitogen-activated protein kinase kinase binding	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0031996	thioesterase binding	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0035374	chondroitin sulfate binding	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0042166	acetylcholine binding	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0043121	neurotrophin binding	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0043208	glycosphingolipid binding	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0047429	nucleoside triphosphate diphosphatase activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0050815	phosphoserine residue binding	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0051864	histone H3K36 demethylase activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0051880	G-quadruplex DNA binding	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0097177	mitochondrial ribosome binding	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0098505	G-rich strand telomeric DNA binding	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0140135	mechanosensitive monoatomic cation channel activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0140940	histone H2A methyltransferase activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:1905394	retromer complex binding	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:1990259	histone H2AQ104 methyltransferase activity	1/1670	10/18639	0.1	1.11610778443114	0.608949192252413	0.896549292689698
GO:0042562	hormone binding	8/1670	94/18639	0.0851063829787234	0.949878965473309	0.613538279155682	0.899238216528799
GO:0061733	protein-lysine-acetyltransferase activity	4/1670	47/18639	0.0851063829787234	0.949878965473309	0.617447304544646	0.899238216528799
GO:0000175	3'-5'-RNA exonuclease activity	3/1670	35/18639	0.0857142857142857	0.956663815226689	0.618195160201116	0.899238216528799
GO:0004623	phospholipase A2 activity	3/1670	35/18639	0.0857142857142857	0.956663815226689	0.618195160201116	0.899238216528799
GO:0010485	histone H4 acetyltransferase activity	3/1670	35/18639	0.0857142857142857	0.956663815226689	0.618195160201116	0.899238216528799
GO:0043015	gamma-tubulin binding	3/1670	35/18639	0.0857142857142857	0.956663815226689	0.618195160201116	0.899238216528799
GO:0140299	molecular sensor activity	6/1670	71/18639	0.0845070422535211	0.94318967698406	0.620509110069801	0.899238216528799
GO:0061659	ubiquitin-like protein ligase activity	32/1670	372/18639	0.0860215053763441	0.960092717790226	0.623204035467819	0.899238216528799
GO:0000295	adenine nucleotide transmembrane transporter activity	2/1670	23/18639	0.0869565217391304	0.970528508200989	0.623406496289937	0.899238216528799
GO:0005212	structural constituent of eye lens	2/1670	23/18639	0.0869565217391304	0.970528508200989	0.623406496289937	0.899238216528799
GO:0016849	phosphorus-oxygen lyase activity	2/1670	23/18639	0.0869565217391304	0.970528508200989	0.623406496289937	0.899238216528799
GO:0017134	fibroblast growth factor binding	2/1670	23/18639	0.0869565217391304	0.970528508200989	0.623406496289937	0.899238216528799
GO:0044013	histone H2B acetyltransferase activity	2/1670	23/18639	0.0869565217391304	0.970528508200989	0.623406496289937	0.899238216528799
GO:0140103	catalytic activity, acting on a glycoprotein	2/1670	23/18639	0.0869565217391304	0.970528508200989	0.623406496289937	0.899238216528799
GO:0008514	organic anion transmembrane transporter activity	23/1670	269/18639	0.0855018587360595	0.954292901186475	0.625043774631997	0.899238216528799
GO:0020037	heme binding	12/1670	142/18639	0.0845070422535211	0.94318967698406	0.627427014525001	0.899238216528799
GO:0005506	iron ion binding	13/1670	154/18639	0.0844155844155844	0.942168908935376	0.630741624836242	0.899238216528799
GO:0001098	basal transcription machinery binding	5/1670	60/18639	0.0833333333333333	0.930089820359281	0.633604067511593	0.899238216528799
GO:0001099	basal RNA polymerase II transcription machinery binding	5/1670	60/18639	0.0833333333333333	0.930089820359281	0.633604067511593	0.899238216528799
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	4/1670	48/18639	0.0833333333333333	0.930089820359281	0.634269559910643	0.899238216528799
GO:0005262	calcium channel activity	11/1670	131/18639	0.083969465648855	0.9371897426521	0.634280468298304	0.899238216528799
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0004016	adenylate cyclase activity	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0005225	volume-sensitive anion channel activity	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0031731	CCR6 chemokine receptor binding	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0032404	mismatch repair complex binding	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0032794	GTPase activating protein binding	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0034056	estrogen response element binding	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0034713	type I transforming growth factor beta receptor binding	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0050998	nitric-oxide synthase binding	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0070990	snRNP binding	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0097493	structural molecule activity conferring elasticity	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0140537	transcription regulator activator activity	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/1670	11/18639	0.0909090909090909	1.01464344039194	0.644005011079966	0.899238216528799
GO:0005540	hyaluronic acid binding	2/1670	24/18639	0.0833333333333333	0.930089820359281	0.646833381611141	0.899238216528799
GO:0043998	histone H2A acetyltransferase activity	2/1670	24/18639	0.0833333333333333	0.930089820359281	0.646833381611141	0.899238216528799
GO:0070300	phosphatidic acid binding	2/1670	24/18639	0.0833333333333333	0.930089820359281	0.646833381611141	0.899238216528799
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/1670	24/18639	0.0833333333333333	0.930089820359281	0.646833381611141	0.899238216528799
GO:0070840	dynein complex binding	2/1670	24/18639	0.0833333333333333	0.930089820359281	0.646833381611141	0.899238216528799
GO:0061630	ubiquitin protein ligase activity	30/1670	353/18639	0.084985835694051	0.94853352784516	0.647726251707082	0.899456226802335
GO:0030551	cyclic nucleotide binding	3/1670	37/18639	0.0810810810810811	0.904952257646868	0.656181167916287	0.905536426244515
GO:0015605	organophosphate ester transmembrane transporter activity	4/1670	50/18639	0.08	0.89288622754491	0.666446964266409	0.905536426244515
GO:0003707	nuclear steroid receptor activity	2/1670	25/18639	0.08	0.89288622754491	0.669088389173819	0.905536426244515
GO:0004709	MAP kinase kinase kinase activity	2/1670	25/18639	0.08	0.89288622754491	0.669088389173819	0.905536426244515
GO:0008483	transaminase activity	2/1670	25/18639	0.08	0.89288622754491	0.669088389173819	0.905536426244515
GO:0015296	monoatomic anion:monoatomic cation symporter activity	2/1670	25/18639	0.08	0.89288622754491	0.669088389173819	0.905536426244515
GO:0019211	phosphatase activator activity	2/1670	25/18639	0.08	0.89288622754491	0.669088389173819	0.905536426244515
GO:0047617	fatty acyl-CoA hydrolase activity	2/1670	25/18639	0.08	0.89288622754491	0.669088389173819	0.905536426244515
GO:0015291	secondary active transmembrane transporter activity	24/1670	287/18639	0.0836236933797909	0.933330551440673	0.669683825980609	0.905536426244515
GO:0005501	retinoid binding	3/1670	38/18639	0.0789473684210526	0.881137724550898	0.674124595771881	0.905536426244515
GO:0019840	isoprenoid binding	3/1670	38/18639	0.0789473684210526	0.881137724550898	0.674124595771881	0.905536426244515
GO:0015085	calcium ion transmembrane transporter activity	12/1670	147/18639	0.0816326530612245	0.91110839545399	0.674919227008495	0.905536426244515
GO:0000340	RNA 7-methylguanosine cap binding	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0003720	telomerase activity	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0004000	adenosine deaminase activity	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0008179	adenylate cyclase binding	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0010853	cyclase activator activity	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0015166	polyol transmembrane transporter activity	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0015368	calcium:monoatomic cation antiporter activity	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0016273	arginine N-methyltransferase activity	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0016274	protein-arginine N-methyltransferase activity	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0016801	hydrolase activity, acting on ether bonds	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0016803	ether hydrolase activity	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0031543	peptidyl-proline dioxygenase activity	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0036009	protein-glutamine N-methyltransferase activity	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0042301	phosphate ion binding	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0043047	single-stranded telomeric DNA binding	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0140900	chloride:bicarbonate antiporter activity	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/1670	12/18639	0.0833333333333333	0.930089820359281	0.675919958014497	0.905536426244515
GO:1901682	sulfur compound transmembrane transporter activity	5/1670	63/18639	0.0793650793650794	0.885799828913601	0.676558721081213	0.905536426244515
GO:0005272	sodium channel activity	4/1670	51/18639	0.0784313725490196	0.875378654455794	0.681789396726947	0.911538996499267
GO:0140034	methylation-dependent protein binding	6/1670	76/18639	0.0789473684210526	0.881137724550898	0.686250337198031	0.914472546872674
GO:0015145	monosaccharide transmembrane transporter activity	2/1670	26/18639	0.0769230769230769	0.858544449562414	0.690193323528625	0.914472546872674
GO:0015216	purine nucleotide transmembrane transporter activity	2/1670	26/18639	0.0769230769230769	0.858544449562414	0.690193323528625	0.914472546872674
GO:0016289	acyl-CoA hydrolase activity	2/1670	26/18639	0.0769230769230769	0.858544449562414	0.690193323528625	0.914472546872674
GO:0030507	spectrin binding	2/1670	26/18639	0.0769230769230769	0.858544449562414	0.690193323528625	0.914472546872674
GO:0034237	protein kinase A regulatory subunit binding	2/1670	26/18639	0.0769230769230769	0.858544449562414	0.690193323528625	0.914472546872674
GO:0097602	cullin family protein binding	2/1670	26/18639	0.0769230769230769	0.858544449562414	0.690193323528625	0.914472546872674
GO:0016757	glycosyltransferase activity	22/1670	267/18639	0.0823970037453183	0.919639372939514	0.692005722024621	0.914472546872674
GO:0015631	tubulin binding	32/1670	385/18639	0.0831168831168831	0.927674002644062	0.699512250187758	0.914472546872674
GO:0019842	vitamin binding	12/1670	150/18639	0.08	0.89288622754491	0.701668530363707	0.914472546872674
GO:0003823	antigen binding	14/1670	174/18639	0.0804597701149425	0.898017757588272	0.702618203564278	0.914472546872674
GO:0002161	aminoacyl-tRNA editing activity	1/1670	13/18639	0.0769230769230769	0.858544449562414	0.704975290065595	0.914472546872674
GO:0003964	RNA-directed DNA polymerase activity	1/1670	13/18639	0.0769230769230769	0.858544449562414	0.704975290065595	0.914472546872674
GO:0005172	vascular endothelial growth factor receptor binding	1/1670	13/18639	0.0769230769230769	0.858544449562414	0.704975290065595	0.914472546872674
GO:0008417	fucosyltransferase activity	1/1670	13/18639	0.0769230769230769	0.858544449562414	0.704975290065595	0.914472546872674
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/1670	13/18639	0.0769230769230769	0.858544449562414	0.704975290065595	0.914472546872674
GO:0019855	calcium channel inhibitor activity	1/1670	13/18639	0.0769230769230769	0.858544449562414	0.704975290065595	0.914472546872674
GO:0031432	titin binding	1/1670	13/18639	0.0769230769230769	0.858544449562414	0.704975290065595	0.914472546872674
GO:0031994	insulin-like growth factor I binding	1/1670	13/18639	0.0769230769230769	0.858544449562414	0.704975290065595	0.914472546872674
GO:0032396	inhibitory MHC class I receptor activity	1/1670	13/18639	0.0769230769230769	0.858544449562414	0.704975290065595	0.914472546872674
GO:0043560	insulin receptor substrate binding	1/1670	13/18639	0.0769230769230769	0.858544449562414	0.704975290065595	0.914472546872674
GO:0061459	L-arginine transmembrane transporter activity	1/1670	13/18639	0.0769230769230769	0.858544449562414	0.704975290065595	0.914472546872674
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/1670	13/18639	0.0769230769230769	0.858544449562414	0.704975290065595	0.914472546872674
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/1670	13/18639	0.0769230769230769	0.858544449562414	0.704975290065595	0.914472546872674
GO:0140666	annealing activity	1/1670	13/18639	0.0769230769230769	0.858544449562414	0.704975290065595	0.914472546872674
GO:0140852	histone ubiquitin ligase activity	1/1670	13/18639	0.0769230769230769	0.858544449562414	0.704975290065595	0.914472546872674
GO:1901338	catecholamine binding	1/1670	13/18639	0.0769230769230769	0.858544449562414	0.704975290065595	0.914472546872674
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	3/1670	40/18639	0.075	0.837080838323353	0.707913497210108	0.914472546872674
GO:0050997	quaternary ammonium group binding	3/1670	40/18639	0.075	0.837080838323353	0.707913497210108	0.914472546872674
GO:0071855	neuropeptide receptor binding	3/1670	40/18639	0.075	0.837080838323353	0.707913497210108	0.914472546872674
GO:0140662	ATP-dependent protein folding chaperone	3/1670	40/18639	0.075	0.837080838323353	0.707913497210108	0.914472546872674
GO:0004683	calcium/calmodulin-dependent protein kinase activity	2/1670	27/18639	0.0740740740740741	0.826746506986028	0.710175488528779	0.914472546872674
GO:0008266	poly(U) RNA binding	2/1670	27/18639	0.0740740740740741	0.826746506986028	0.710175488528779	0.914472546872674
GO:0008320	protein transmembrane transporter activity	2/1670	27/18639	0.0740740740740741	0.826746506986028	0.710175488528779	0.914472546872674
GO:0015252	proton channel activity	2/1670	27/18639	0.0740740740740741	0.826746506986028	0.710175488528779	0.914472546872674
GO:0016251	RNA polymerase II general transcription initiation factor activity	4/1670	53/18639	0.0754716981132075	0.842345497683878	0.710966940315244	0.914528001121292
GO:0005253	monoatomic anion channel activity	8/1670	103/18639	0.0776699029126214	0.866879832567874	0.714513891682991	0.918124054297176
GO:0046906	tetrapyrrole binding	12/1670	152/18639	0.0789473684210526	0.881137724550898	0.718732377095624	0.922574542868543
GO:0031490	chromatin DNA binding	10/1670	128/18639	0.078125	0.871959206586826	0.720433406583425	0.92378764201988
GO:0015370	solute:sodium symporter activity	6/1670	79/18639	0.0759493670886076	0.84767679830213	0.721901796119037	0.924306004762245
GO:0051119	sugar transmembrane transporter activity	2/1670	28/18639	0.0714285714285714	0.797219846022241	0.729066528018584	0.924306004762245
GO:0051537	2 iron, 2 sulfur cluster binding	2/1670	28/18639	0.0714285714285714	0.797219846022241	0.729066528018584	0.924306004762245
GO:0141052	histone H3 demethylase activity	2/1670	28/18639	0.0714285714285714	0.797219846022241	0.729066528018584	0.924306004762245
GO:0005344	oxygen carrier activity	1/1670	14/18639	0.0714285714285714	0.797219846022241	0.731427092148192	0.924306004762245
GO:0008195	phosphatidate phosphatase activity	1/1670	14/18639	0.0714285714285714	0.797219846022241	0.731427092148192	0.924306004762245
GO:0015926	glucosidase activity	1/1670	14/18639	0.0714285714285714	0.797219846022241	0.731427092148192	0.924306004762245
GO:0016530	metallochaperone activity	1/1670	14/18639	0.0714285714285714	0.797219846022241	0.731427092148192	0.924306004762245
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/1670	14/18639	0.0714285714285714	0.797219846022241	0.731427092148192	0.924306004762245
GO:0030983	mismatched DNA binding	1/1670	14/18639	0.0714285714285714	0.797219846022241	0.731427092148192	0.924306004762245
GO:0042813	Wnt receptor activity	1/1670	14/18639	0.0714285714285714	0.797219846022241	0.731427092148192	0.924306004762245
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	1/1670	14/18639	0.0714285714285714	0.797219846022241	0.731427092148192	0.924306004762245
GO:0061783	peptidoglycan muralytic activity	1/1670	14/18639	0.0714285714285714	0.797219846022241	0.731427092148192	0.924306004762245
GO:0098847	sequence-specific single stranded DNA binding	1/1670	14/18639	0.0714285714285714	0.797219846022241	0.731427092148192	0.924306004762245
GO:0051879	Hsp90 protein binding	3/1670	42/18639	0.0714285714285714	0.797219846022241	0.738944162255011	0.932840667640107
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	2/1670	29/18639	0.0689655172413793	0.769729506504233	0.746901429914758	0.937290783851153
GO:0097472	cyclin-dependent protein kinase activity	2/1670	29/18639	0.0689655172413793	0.769729506504233	0.746901429914758	0.937290783851153
GO:0106222	lncRNA binding	2/1670	29/18639	0.0689655172413793	0.769729506504233	0.746901429914758	0.937290783851153
GO:0016410	N-acyltransferase activity	7/1670	94/18639	0.074468085106383	0.831144094789145	0.748480724178861	0.937290783851153
GO:0005245	voltage-gated calcium channel activity	3/1670	43/18639	0.0697674418604651	0.778679849603119	0.753449493831027	0.937290783851153
GO:0008375	acetylglucosaminyltransferase activity	3/1670	43/18639	0.0697674418604651	0.778679849603119	0.753449493831027	0.937290783851153
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	3/1670	43/18639	0.0697674418604651	0.778679849603119	0.753449493831027	0.937290783851153
GO:0008020	G protein-coupled photoreceptor activity	1/1670	15/18639	0.0666666666666667	0.744071856287425	0.755508528717992	0.937290783851153
GO:0008242	omega peptidase activity	1/1670	15/18639	0.0666666666666667	0.744071856287425	0.755508528717992	0.937290783851153
GO:0015250	water channel activity	1/1670	15/18639	0.0666666666666667	0.744071856287425	0.755508528717992	0.937290783851153
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/1670	15/18639	0.0666666666666667	0.744071856287425	0.755508528717992	0.937290783851153
GO:0016846	carbon-sulfur lyase activity	1/1670	15/18639	0.0666666666666667	0.744071856287425	0.755508528717992	0.937290783851153
GO:0033130	acetylcholine receptor binding	1/1670	15/18639	0.0666666666666667	0.744071856287425	0.755508528717992	0.937290783851153
GO:0045504	dynein heavy chain binding	1/1670	15/18639	0.0666666666666667	0.744071856287425	0.755508528717992	0.937290783851153
GO:0061578	K63-linked deubiquitinase activity	1/1670	15/18639	0.0666666666666667	0.744071856287425	0.755508528717992	0.937290783851153
GO:0140161	monocarboxylate:sodium symporter activity	1/1670	15/18639	0.0666666666666667	0.744071856287425	0.755508528717992	0.937290783851153
GO:0140776	protein-containing complex destabilizing activity	1/1670	15/18639	0.0666666666666667	0.744071856287425	0.755508528717992	0.937290783851153
GO:0008236	serine-type peptidase activity	15/1670	194/18639	0.077319587628866	0.862969936415828	0.761825587867822	0.93889637555745
GO:0016782	transferase activity, transferring sulphur-containing groups	5/1670	70/18639	0.0714285714285714	0.797219846022241	0.763130958185654	0.93889637555745
GO:0001965	G-protein alpha-subunit binding	2/1670	30/18639	0.0666666666666667	0.744071856287425	0.763717673734947	0.93889637555745
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/1670	30/18639	0.0666666666666667	0.744071856287425	0.763717673734947	0.93889637555745
GO:0008187	poly-pyrimidine tract binding	2/1670	30/18639	0.0666666666666667	0.744071856287425	0.763717673734947	0.93889637555745
GO:0015215	nucleotide transmembrane transporter activity	2/1670	30/18639	0.0666666666666667	0.744071856287425	0.763717673734947	0.93889637555745
GO:0016769	transferase activity, transferring nitrogenous groups	2/1670	30/18639	0.0666666666666667	0.744071856287425	0.763717673734947	0.93889637555745
GO:0032452	histone demethylase activity	2/1670	30/18639	0.0666666666666667	0.744071856287425	0.763717673734947	0.93889637555745
GO:0070566	adenylyltransferase activity	2/1670	30/18639	0.0666666666666667	0.744071856287425	0.763717673734947	0.93889637555745
GO:0005254	chloride channel activity	6/1670	83/18639	0.072289156626506	0.806824904408051	0.764890918581116	0.939393670860426
GO:0140658	ATP-dependent chromatin remodeler activity	12/1670	158/18639	0.0759493670886076	0.84767679830213	0.766105665144332	0.939862653110144
GO:0015108	chloride transmembrane transporter activity	9/1670	121/18639	0.0743801652892562	0.830162814866136	0.76681101894502	0.939862653110144
GO:0008142	oxysterol binding	1/1670	16/18639	0.0625	0.697567365269461	0.777431894108937	0.945993648212534
GO:0015562	efflux transmembrane transporter activity	1/1670	16/18639	0.0625	0.697567365269461	0.777431894108937	0.945993648212534
GO:0019841	retinol binding	1/1670	16/18639	0.0625	0.697567365269461	0.777431894108937	0.945993648212534
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/1670	16/18639	0.0625	0.697567365269461	0.777431894108937	0.945993648212534
GO:0022858	alanine transmembrane transporter activity	1/1670	16/18639	0.0625	0.697567365269461	0.777431894108937	0.945993648212534
GO:0034450	ubiquitin-ubiquitin ligase activity	1/1670	16/18639	0.0625	0.697567365269461	0.777431894108937	0.945993648212534
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/1670	31/18639	0.0645161290322581	0.72006953834267	0.779554503887088	0.945993648212534
GO:0008327	methyl-CpG binding	2/1670	31/18639	0.0645161290322581	0.72006953834267	0.779554503887088	0.945993648212534
GO:0072349	modified amino acid transmembrane transporter activity	2/1670	31/18639	0.0645161290322581	0.72006953834267	0.779554503887088	0.945993648212534
GO:0140457	protein demethylase activity	2/1670	31/18639	0.0645161290322581	0.72006953834267	0.779554503887088	0.945993648212534
GO:0004715	non-membrane spanning protein tyrosine kinase activity	3/1670	45/18639	0.0666666666666667	0.744071856287425	0.780506667328177	0.946209471701421
GO:0070063	RNA polymerase binding	4/1670	59/18639	0.0677966101694915	0.756683243682127	0.78659236146914	0.951573404317577
GO:0017171	serine hydrolase activity	15/1670	198/18639	0.0757575757575758	0.845536200326619	0.787950802789553	0.951573404317577
GO:0008509	monoatomic anion transmembrane transporter activity	11/1670	149/18639	0.0738255033557047	0.823972189848491	0.790588182190732	0.951573404317577
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3/1670	46/18639	0.0652173913043478	0.727896381150742	0.793089780615084	0.951573404317577
GO:0043539	protein serine/threonine kinase activator activity	5/1670	73/18639	0.0684931506849315	0.76445738659667	0.794405170358294	0.951573404317577
GO:0015106	bicarbonate transmembrane transporter activity	2/1670	32/18639	0.0625	0.697567365269461	0.794452313048194	0.951573404317577
GO:0042910	xenobiotic transmembrane transporter activity	2/1670	32/18639	0.0625	0.697567365269461	0.794452313048194	0.951573404317577
GO:0047498	calcium-dependent phospholipase A2 activity	2/1670	32/18639	0.0625	0.697567365269461	0.794452313048194	0.951573404317577
GO:0070717	poly-purine tract binding	2/1670	32/18639	0.0625	0.697567365269461	0.794452313048194	0.951573404317577
GO:0004549	tRNA-specific ribonuclease activity	1/1670	17/18639	0.0588235294117647	0.656533990841846	0.797390479559083	0.951573404317577
GO:0005092	GDP-dissociation inhibitor activity	1/1670	17/18639	0.0588235294117647	0.656533990841846	0.797390479559083	0.951573404317577
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	1/1670	17/18639	0.0588235294117647	0.656533990841846	0.797390479559083	0.951573404317577
GO:0009881	photoreceptor activity	1/1670	17/18639	0.0588235294117647	0.656533990841846	0.797390479559083	0.951573404317577
GO:0030548	acetylcholine receptor regulator activity	1/1670	17/18639	0.0588235294117647	0.656533990841846	0.797390479559083	0.951573404317577
GO:0032977	membrane insertase activity	1/1670	17/18639	0.0588235294117647	0.656533990841846	0.797390479559083	0.951573404317577
GO:0070402	NADPH binding	1/1670	17/18639	0.0588235294117647	0.656533990841846	0.797390479559083	0.951573404317577
GO:0003684	damaged DNA binding	5/1670	74/18639	0.0675675675675676	0.75412688137239	0.804080863963224	0.9535249631008
GO:0035064	methylated histone binding	5/1670	74/18639	0.0675675675675676	0.75412688137239	0.804080863963224	0.9535249631008
GO:0048029	monosaccharide binding	5/1670	74/18639	0.0675675675675676	0.75412688137239	0.804080863963224	0.9535249631008
GO:0000510	H3-H4 histone complex chaperone activity	11/1670	151/18639	0.0728476821192053	0.8130586509101	0.80448791895002	0.9535249631008
GO:0140584	chromatin extrusion motor activity	11/1670	151/18639	0.0728476821192053	0.8130586509101	0.80448791895002	0.9535249631008
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	11/1670	151/18639	0.0728476821192053	0.8130586509101	0.80448791895002	0.9535249631008
GO:0140849	ATP-dependent H2AZ histone chaperone activity	11/1670	151/18639	0.0728476821192053	0.8130586509101	0.80448791895002	0.9535249631008
GO:0015081	sodium ion transmembrane transporter activity	12/1670	164/18639	0.0731707317073171	0.816664232510589	0.807674374337839	0.955655260311305
GO:0042923	neuropeptide binding	2/1670	33/18639	0.0606060606060606	0.676428960261296	0.808452121757297	0.955655260311305
GO:0015616	DNA translocase activity	11/1670	152/18639	0.0723684210526316	0.807709580838323	0.811178067605327	0.955655260311305
GO:0140674	ATP-dependent histone chaperone activity	11/1670	152/18639	0.0723684210526316	0.807709580838323	0.811178067605327	0.955655260311305
GO:0042826	histone deacetylase binding	9/1670	127/18639	0.0708661417322835	0.790942524400019	0.813393974245521	0.955655260311305
GO:0008017	microtubule binding	21/1670	276/18639	0.0760869565217391	0.849212444675866	0.814081442349026	0.955655260311305
GO:0004706	JUN kinase kinase kinase activity	1/1670	18/18639	0.0555555555555556	0.620059880239521	0.815560273304993	0.955655260311305
GO:0005372	water transmembrane transporter activity	1/1670	18/18639	0.0555555555555556	0.620059880239521	0.815560273304993	0.955655260311305
GO:0017128	phospholipid scramblase activity	1/1670	18/18639	0.0555555555555556	0.620059880239521	0.815560273304993	0.955655260311305
GO:0032393	MHC class I receptor activity	1/1670	18/18639	0.0555555555555556	0.620059880239521	0.815560273304993	0.955655260311305
GO:0099602	neurotransmitter receptor regulator activity	1/1670	18/18639	0.0555555555555556	0.620059880239521	0.815560273304993	0.955655260311305
GO:0016879	ligase activity, forming carbon-nitrogen bonds	3/1670	48/18639	0.0625	0.697567365269461	0.816451793588382	0.955655260311305
GO:0032266	phosphatidylinositol-3-phosphate binding	3/1670	48/18639	0.0625	0.697567365269461	0.816451793588382	0.955655260311305
GO:0061775	cohesin loader activity	11/1670	153/18639	0.0718954248366013	0.802430433251145	0.817696708751284	0.955656482068109
GO:0015179	L-amino acid transmembrane transporter activity	4/1670	62/18639	0.0645161290322581	0.72006953834267	0.818016923275976	0.955656482068109
GO:0015171	amino acid transmembrane transporter activity	7/1670	102/18639	0.0686274509803922	0.76595632264882	0.819012281336032	0.955905451568893
GO:0015035	protein-disulfide reductase activity	2/1670	34/18639	0.0588235294117647	0.656533990841846	0.821595141947673	0.957091766882799
GO:0019825	oxygen binding	2/1670	34/18639	0.0588235294117647	0.656533990841846	0.821595141947673	0.957091766882799
GO:0000287	magnesium ion binding	17/1670	230/18639	0.0739130434782609	0.824949231970841	0.829569137715981	0.959271739230964
GO:0004386	helicase activity	11/1670	155/18639	0.0709677419354839	0.792076492176936	0.83022538839338	0.959271739230964
GO:0003756	protein disulfide isomerase activity	1/1670	19/18639	0.0526315789473684	0.587425149700599	0.832101508661883	0.959271739230964
GO:0005229	intracellularly calcium-gated chloride channel activity	1/1670	19/18639	0.0526315789473684	0.587425149700599	0.832101508661883	0.959271739230964
GO:0005520	insulin-like growth factor binding	1/1670	19/18639	0.0526315789473684	0.587425149700599	0.832101508661883	0.959271739230964
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/1670	19/18639	0.0526315789473684	0.587425149700599	0.832101508661883	0.959271739230964
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/1670	19/18639	0.0526315789473684	0.587425149700599	0.832101508661883	0.959271739230964
GO:0034987	immunoglobulin receptor binding	1/1670	19/18639	0.0526315789473684	0.587425149700599	0.832101508661883	0.959271739230964
GO:0042834	peptidoglycan binding	1/1670	19/18639	0.0526315789473684	0.587425149700599	0.832101508661883	0.959271739230964
GO:0141147	intracellularly calcium-gated channel activity	1/1670	19/18639	0.0526315789473684	0.587425149700599	0.832101508661883	0.959271739230964
GO:1990380	K48-linked deubiquitinase activity	1/1670	19/18639	0.0526315789473684	0.587425149700599	0.832101508661883	0.959271739230964
GO:0034061	DNA polymerase activity	2/1670	35/18639	0.0571428571428571	0.637775876817793	0.833922413568676	0.959560441978269
GO:0140566	histone reader activity	2/1670	35/18639	0.0571428571428571	0.637775876817793	0.833922413568676	0.959560441978269
GO:0004033	aldo-keto reductase (NADPH) activity	2/1670	36/18639	0.0555555555555556	0.620059880239521	0.845474504716162	0.966600943072102
GO:0016409	palmitoyltransferase activity	2/1670	36/18639	0.0555555555555556	0.620059880239521	0.845474504716162	0.966600943072102
GO:0000339	RNA cap binding	1/1670	20/18639	0.05	0.558053892215569	0.847160073674486	0.966600943072102
GO:0001972	retinoic acid binding	1/1670	20/18639	0.05	0.558053892215569	0.847160073674486	0.966600943072102
GO:0015095	magnesium ion transmembrane transporter activity	1/1670	20/18639	0.05	0.558053892215569	0.847160073674486	0.966600943072102
GO:0015464	acetylcholine receptor activity	1/1670	20/18639	0.05	0.558053892215569	0.847160073674486	0.966600943072102
GO:0016505	peptidase activator activity involved in apoptotic process	1/1670	20/18639	0.05	0.558053892215569	0.847160073674486	0.966600943072102
GO:0061608	nuclear import signal receptor activity	1/1670	20/18639	0.05	0.558053892215569	0.847160073674486	0.966600943072102
GO:0140939	histone H4 methyltransferase activity	1/1670	20/18639	0.05	0.558053892215569	0.847160073674486	0.966600943072102
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	3/1670	52/18639	0.0576923076923077	0.64390833717181	0.856489704258479	0.973156028802813
GO:0003689	DNA clamp loader activity	11/1670	160/18639	0.06875	0.767324101796407	0.858664510954999	0.973156028802813
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/1670	21/18639	0.0476190476190476	0.531479897348161	0.860868794710181	0.973156028802813
GO:0005248	voltage-gated sodium channel activity	1/1670	21/18639	0.0476190476190476	0.531479897348161	0.860868794710181	0.973156028802813
GO:0008373	sialyltransferase activity	1/1670	21/18639	0.0476190476190476	0.531479897348161	0.860868794710181	0.973156028802813
GO:0009931	calcium-dependent protein serine/threonine kinase activity	1/1670	21/18639	0.0476190476190476	0.531479897348161	0.860868794710181	0.973156028802813
GO:0009975	cyclase activity	1/1670	21/18639	0.0476190476190476	0.531479897348161	0.860868794710181	0.973156028802813
GO:0051428	peptide hormone receptor binding	1/1670	21/18639	0.0476190476190476	0.531479897348161	0.860868794710181	0.973156028802813
GO:0072542	protein phosphatase activator activity	1/1670	21/18639	0.0476190476190476	0.531479897348161	0.860868794710181	0.973156028802813
GO:1904047	S-adenosyl-L-methionine binding	1/1670	21/18639	0.0476190476190476	0.531479897348161	0.860868794710181	0.973156028802813
GO:0106310	protein serine kinase activity	27/1670	361/18639	0.074792243767313	0.834762054837693	0.862908779529152	0.974560562462684
GO:0008146	sulfotransferase activity	3/1670	53/18639	0.0566037735849057	0.631759123262908	0.865221070095073	0.975369139904224
GO:0017046	peptide hormone binding	3/1670	53/18639	0.0566037735849057	0.631759123262908	0.865221070095073	0.975369139904224
GO:0140223	general transcription initiation factor activity	4/1670	68/18639	0.0588235294117647	0.656533990841846	0.869445772480682	0.977194125880558
GO:0140597	protein carrier chaperone	13/1670	188/18639	0.0691489361702128	0.771776659447063	0.870017046801745	0.977194125880558
GO:0004222	metalloendopeptidase activity	7/1670	110/18639	0.0636363636363636	0.71025040827436	0.873093357924659	0.977194125880558
GO:0005243	gap junction channel activity	1/1670	22/18639	0.0454545454545455	0.507321720195972	0.873348605260938	0.977194125880558
GO:0016881	acid-amino acid ligase activity	1/1670	22/18639	0.0454545454545455	0.507321720195972	0.873348605260938	0.977194125880558
GO:0033691	sialic acid binding	1/1670	22/18639	0.0454545454545455	0.507321720195972	0.873348605260938	0.977194125880558
GO:0050321	tau-protein kinase activity	1/1670	22/18639	0.0454545454545455	0.507321720195972	0.873348605260938	0.977194125880558
GO:0140463	chromatin-protein adaptor activity	3/1670	54/18639	0.0555555555555556	0.620059880239521	0.873481005219375	0.977194125880558
GO:0004252	serine-type endopeptidase activity	12/1670	176/18639	0.0681818181818182	0.760982580293957	0.874036971839157	0.977194125880558
GO:0140713	histone chaperone activity	11/1670	164/18639	0.0670731707317073	0.748608879801373	0.878593742538459	0.981052519695889
GO:0003887	DNA-directed DNA polymerase activity	1/1670	23/18639	0.0434782608695652	0.485264254100495	0.884709610214165	0.981052519695889
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/1670	23/18639	0.0434782608695652	0.485264254100495	0.884709610214165	0.981052519695889
GO:0008171	O-methyltransferase activity	1/1670	23/18639	0.0434782608695652	0.485264254100495	0.884709610214165	0.981052519695889
GO:0031681	G-protein beta-subunit binding	1/1670	23/18639	0.0434782608695652	0.485264254100495	0.884709610214165	0.981052519695889
GO:0070577	lysine-acetylated histone binding	1/1670	23/18639	0.0434782608695652	0.485264254100495	0.884709610214165	0.981052519695889
GO:0140102	catalytic activity, acting on a rRNA	1/1670	23/18639	0.0434782608695652	0.485264254100495	0.884709610214165	0.981052519695889
GO:0004177	aminopeptidase activity	2/1670	40/18639	0.05	0.558053892215569	0.884713483391874	0.981052519695889
GO:0032451	demethylase activity	2/1670	40/18639	0.05	0.558053892215569	0.884713483391874	0.981052519695889
GO:0016853	isomerase activity	12/1670	180/18639	0.0666666666666667	0.744071856287425	0.891582895334724	0.985363613632285
GO:0019783	ubiquitin-like protein peptidase activity	8/1670	127/18639	0.062992125984252	0.703060021688906	0.891703868455426	0.985363613632285
GO:0008227	G protein-coupled amine receptor activity	2/1670	41/18639	0.0487804878048781	0.544442821673726	0.892967030428573	0.985363613632285
GO:0140828	metal cation:monoatomic cation antiporter activity	2/1670	41/18639	0.0487804878048781	0.544442821673726	0.892967030428573	0.985363613632285
GO:0015149	hexose transmembrane transporter activity	1/1670	24/18639	0.0416666666666667	0.465044910179641	0.895052054936036	0.985363613632285
GO:0055056	D-glucose transmembrane transporter activity	1/1670	24/18639	0.0416666666666667	0.465044910179641	0.895052054936036	0.985363613632285
GO:0140033	acetylation-dependent protein binding	1/1670	24/18639	0.0416666666666667	0.465044910179641	0.895052054936036	0.985363613632285
GO:0140612	DNA damage sensor activity	1/1670	24/18639	0.0416666666666667	0.465044910179641	0.895052054936036	0.985363613632285
GO:0101005	deubiquitinase activity	7/1670	115/18639	0.0608695652173913	0.679369955740693	0.899555614119862	0.989430207429768
GO:0008139	nuclear localization sequence binding	1/1670	25/18639	0.04	0.446443113772455	0.904467207676128	0.989488744655532
GO:0015662	P-type ion transporter activity	1/1670	25/18639	0.04	0.446443113772455	0.904467207676128	0.989488744655532
GO:0017056	structural constituent of nuclear pore	1/1670	25/18639	0.04	0.446443113772455	0.904467207676128	0.989488744655532
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/1670	25/18639	0.04	0.446443113772455	0.904467207676128	0.989488744655532
GO:0019707	protein-cysteine S-acyltransferase activity	1/1670	25/18639	0.04	0.446443113772455	0.904467207676128	0.989488744655532
GO:0140358	P-type transmembrane transporter activity	1/1670	25/18639	0.04	0.446443113772455	0.904467207676128	0.989488744655532
GO:0140104	molecular carrier activity	17/1670	249/18639	0.0682730923694779	0.762001298607604	0.90702911095318	0.990234667652133
GO:0004712	protein serine/threonine/tyrosine kinase activity	2/1670	43/18639	0.0465116279069767	0.519119899735413	0.907849572861945	0.990234667652133
GO:0015459	potassium channel regulator activity	3/1670	59/18639	0.0508474576271186	0.567512432761595	0.908390394793814	0.990234667652133
GO:0070888	E-box binding	3/1670	59/18639	0.0508474576271186	0.567512432761595	0.908390394793814	0.990234667652133
GO:0003727	single-stranded RNA binding	5/1670	89/18639	0.0561797752808989	0.627026845186032	0.909903237289774	0.990881558825363
GO:0008194	UDP-glycosyltransferase activity	9/1670	145/18639	0.0620689655172414	0.69275655585381	0.911165893811307	0.990881558825363
GO:0008143	poly(A) binding	1/1670	26/18639	0.0384615384615385	0.429272224781207	0.913038163042029	0.990881558825363
GO:0051139	metal cation:proton antiporter activity	1/1670	26/18639	0.0384615384615385	0.429272224781207	0.913038163042029	0.990881558825363
GO:0070006	metalloaminopeptidase activity	1/1670	26/18639	0.0384615384615385	0.429272224781207	0.913038163042029	0.990881558825363
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	3/1670	60/18639	0.05	0.558053892215569	0.914225673638129	0.991289949588105
GO:0016836	hydro-lyase activity	3/1670	61/18639	0.0491803278688525	0.548905467753019	0.919720544700289	0.996363923425313
GO:0008395	steroid hydroxylase activity	1/1670	27/18639	0.037037037037037	0.413373253493014	0.920840573600231	0.996693694366237
GO:0003697	single-stranded DNA binding	7/1670	121/18639	0.0578512396694215	0.645682189340328	0.924978495105167	0.999999998406233
GO:0016866	intramolecular transferase activity	1/1670	28/18639	0.0357142857142857	0.398609923011121	0.92794331602918	0.999999998406233
GO:0050698	proteoglycan sulfotransferase activity	1/1670	28/18639	0.0357142857142857	0.398609923011121	0.92794331602918	0.999999998406233
GO:0043021	ribonucleoprotein complex binding	11/1670	177/18639	0.0621468926553672	0.693626306708617	0.928164826458449	0.999999998406233
GO:0061749	forked DNA-dependent helicase activity	2/1670	47/18639	0.0425531914893617	0.474939482736654	0.931981324567176	0.999999998406233
GO:0140359	ABC-type transporter activity	2/1670	47/18639	0.0425531914893617	0.474939482736654	0.931981324567176	0.999999998406233
GO:1990518	single-stranded 3'-5' DNA helicase activity	2/1670	47/18639	0.0425531914893617	0.474939482736654	0.931981324567176	0.999999998406233
GO:0140097	catalytic activity, acting on DNA	23/1670	336/18639	0.068452380952381	0.764002352437981	0.933237190479506	0.999999998406233
GO:0016417	S-acyltransferase activity	1/1670	29/18639	0.0344827586206897	0.384864753252116	0.934409097676124	0.999999998406233
GO:0000049	tRNA binding	4/1670	80/18639	0.05	0.558053892215569	0.935859494696145	0.999999998406233
GO:0008188	neuropeptide receptor activity	2/1670	48/18639	0.0416666666666667	0.465044910179641	0.93700434765321	0.999999998406233
GO:0009378	four-way junction helicase activity	2/1670	48/18639	0.0416666666666667	0.465044910179641	0.93700434765321	0.999999998406233
GO:0036121	double-stranded DNA helicase activity	2/1670	48/18639	0.0416666666666667	0.465044910179641	0.93700434765321	0.999999998406233
GO:0043138	3'-5' DNA helicase activity	2/1670	48/18639	0.0416666666666667	0.465044910179641	0.93700434765321	0.999999998406233
GO:0042393	histone binding	16/1670	247/18639	0.0647773279352227	0.722984799631506	0.937129143314755	0.999999998406233
GO:0016874	ligase activity	10/1670	167/18639	0.0598802395209581	0.668328014629424	0.938614875215873	0.999999998406233
GO:0016887	ATP hydrolysis activity	29/1670	417/18639	0.0695443645083933	0.776190065911343	0.942093979111889	0.999999998406233
GO:0005184	neuropeptide hormone activity	1/1670	31/18639	0.032258064516129	0.360034769171335	0.94565302567849	0.999999998406233
GO:0005452	solute:inorganic anion antiporter activity	1/1670	31/18639	0.032258064516129	0.360034769171335	0.94565302567849	0.999999998406233
GO:0017147	Wnt-protein binding	1/1670	31/18639	0.032258064516129	0.360034769171335	0.94565302567849	0.999999998406233
GO:0005048	signal sequence binding	2/1670	51/18639	0.0392156862745098	0.437689327227897	0.950043647721847	0.999999998406233
GO:0030515	snoRNA binding	1/1670	32/18639	0.03125	0.348783682634731	0.950530468021403	0.999999998406233
GO:0140142	nucleocytoplasmic carrier activity	1/1670	32/18639	0.03125	0.348783682634731	0.950530468021403	0.999999998406233
GO:0160041	neuropeptide activity	1/1670	32/18639	0.03125	0.348783682634731	0.950530468021403	0.999999998406233
GO:0140098	catalytic activity, acting on RNA	26/1670	387/18639	0.0671834625322997	0.749839855173374	0.955217836421701	0.999999998406233
GO:0008175	tRNA methyltransferase activity	1/1670	34/18639	0.0294117647058824	0.328266995420923	0.959012091323807	0.999999998406233
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/1670	34/18639	0.0294117647058824	0.328266995420923	0.959012091323807	0.999999998406233
GO:0015297	antiporter activity	7/1670	135/18639	0.0518518518518519	0.57872255489022	0.963622190342263	0.999999998406233
GO:0015103	inorganic anion transmembrane transporter activity	9/1670	165/18639	0.0545454545454545	0.608786064235166	0.965184931575394	0.999999998406233
GO:0000993	RNA polymerase II complex binding	1/1670	36/18639	0.0277777777777778	0.31002994011976	0.966040247915273	0.999999998406233
GO:0004190	aspartic-type endopeptidase activity	1/1670	36/18639	0.0277777777777778	0.31002994011976	0.966040247915273	0.999999998406233
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/1670	36/18639	0.0277777777777778	0.31002994011976	0.966040247915273	0.999999998406233
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	2/1670	56/18639	0.0357142857142857	0.398609923011121	0.966240060957006	0.999999998406233
GO:0008094	ATP-dependent activity, acting on DNA	12/1670	210/18639	0.0571428571428571	0.637775876817793	0.969001715545453	0.999999998406233
GO:0022829	wide pore channel activity	1/1670	37/18639	0.027027027027027	0.301650752548956	0.969088830723503	0.999999998406233
GO:0030280	structural constituent of skin epidermis	1/1670	37/18639	0.027027027027027	0.301650752548956	0.969088830723503	0.999999998406233
GO:0070001	aspartic-type peptidase activity	1/1670	37/18639	0.027027027027027	0.301650752548956	0.969088830723503	0.999999998406233
GO:0004843	cysteine-type deubiquitinase activity	5/1670	108/18639	0.0462962962962963	0.516716566866267	0.970081515646406	0.999999998406233
GO:0016758	hexosyltransferase activity	11/1670	197/18639	0.0558375634517767	0.623207392321955	0.97051541948291	0.999999998406233
GO:0017116	single-stranded DNA helicase activity	2/1670	58/18639	0.0344827586206897	0.384864753252116	0.971186704317659	0.999999998406233
GO:0051536	iron-sulfur cluster binding	3/1670	76/18639	0.0394736842105263	0.440568862275449	0.971448370441175	0.999999998406233
GO:0042162	telomeric DNA binding	1/1670	38/18639	0.0263157894736842	0.293712574850299	0.971863890001632	0.999999998406233
GO:0036002	pre-mRNA binding	2/1670	59/18639	0.0338983050847458	0.378341621841064	0.973390083599197	0.999999998406233
GO:0051540	metal cluster binding	3/1670	77/18639	0.038961038961039	0.434847188739404	0.973412986592747	0.999999998406233
GO:0000217	DNA secondary structure binding	1/1670	39/18639	0.0256410256410256	0.286181483187471	0.974389953315286	0.999999998406233
GO:0043022	ribosome binding	5/1670	112/18639	0.0446428571428571	0.498262403763901	0.976599694725597	0.999999998406233
GO:0016835	carbon-oxygen lyase activity	3/1670	79/18639	0.0379746835443038	0.423838399151065	0.976963805992062	0.999999998406233
GO:0035198	miRNA binding	1/1670	42/18639	0.0238095238095238	0.26573994867408	0.980687633191494	0.999999998406233
GO:0043175	RNA polymerase core enzyme binding	1/1670	42/18639	0.0238095238095238	0.26573994867408	0.980687633191494	0.999999998406233
GO:0030020	extracellular matrix structural constituent conferring tensile strength	1/1670	44/18639	0.0227272727272727	0.253660860097986	0.984000463417511	0.999999998406233
GO:0051539	4 iron, 4 sulfur cluster binding	1/1670	45/18639	0.0222222222222222	0.248023952095808	0.985437367213841	0.999999998406233
GO:0099094	ligand-gated monoatomic cation channel activity	6/1670	136/18639	0.0441176470588235	0.492400493131384	0.985704206720666	0.999999998406233
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/1670	46/18639	0.0217391304347826	0.242632127050247	0.986745294327581	0.999999998406233
GO:0030145	manganese ion binding	2/1670	68/18639	0.0294117647058824	0.328266995420923	0.987111671213531	0.999999998406233
GO:0008528	G protein-coupled peptide receptor activity	5/1670	122/18639	0.040983606557377	0.457421223127515	0.987560191777034	0.999999998406233
GO:0099095	ligand-gated monoatomic anion channel activity	1/1670	47/18639	0.0212765957446809	0.237469741368327	0.987935815409329	0.999999998406233
GO:0140938	histone H3 methyltransferase activity	1/1670	47/18639	0.0212765957446809	0.237469741368327	0.987935815409329	0.999999998406233
GO:0098960	postsynaptic neurotransmitter receptor activity	2/1670	69/18639	0.0289855072463768	0.323509502733663	0.988119899795793	0.999999998406233
GO:0001653	peptide receptor activity	5/1670	128/18639	0.0390625	0.435979603293413	0.99157791589414	0.999999998406233
GO:0003678	DNA helicase activity	2/1670	74/18639	0.027027027027027	0.301650752548956	0.992113271227742	0.999999998406233
GO:0046873	metal ion transmembrane transporter activity	27/1670	450/18639	0.06	0.669664670658683	0.99229321898143	0.999999998406233
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/1670	53/18639	0.0188679245283019	0.210586374420969	0.993141693857861	0.999999998406233
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	8/1670	181/18639	0.0441988950276243	0.493307308035862	0.99348423787455	0.999999998406233
GO:0015276	ligand-gated monoatomic ion channel activity	8/1670	186/18639	0.043010752688172	0.480046358895113	0.995139059993977	0.999999998406233
GO:0022834	ligand-gated channel activity	8/1670	188/18639	0.0425531914893617	0.474939482736654	0.995682089977566	0.999999998406233
GO:0061980	regulatory RNA binding	1/1670	58/18639	0.0172413793103448	0.192432376626058	0.99571695622315	0.999999998406233
GO:0140101	catalytic activity, acting on a tRNA	5/1670	139/18639	0.0359712230215827	0.40147762029897	0.995957310807792	0.999999998406233
GO:0022832	voltage-gated channel activity	7/1670	175/18639	0.04	0.446443113772455	0.996465807135505	0.999999998406233
GO:0004497	monooxygenase activity	3/1670	106/18639	0.0283018867924528	0.315879561631454	0.996940002668471	0.999999998406233
GO:0022836	gated channel activity	16/1670	318/18639	0.050314465408805	0.561563665122585	0.997136644605376	0.999999998406233
GO:0005216	monoatomic ion channel activity	25/1670	448/18639	0.0558035714285714	0.622828004704876	0.997254598382838	0.999999998406233
GO:0022824	transmitter-gated monoatomic ion channel activity	1/1670	63/18639	0.0158730158730159	0.17715996578272	0.997325574779787	0.999999998406233
GO:0022835	transmitter-gated channel activity	1/1670	63/18639	0.0158730158730159	0.17715996578272	0.997325574779787	0.999999998406233
GO:0008173	RNA methyltransferase activity	1/1670	67/18639	0.0149253731343284	0.166583251407632	0.998165273855818	0.999999998406233
GO:0042054	histone methyltransferase activity	1/1670	67/18639	0.0149253731343284	0.166583251407632	0.998165273855818	0.999999998406233
GO:0016279	protein-lysine N-methyltransferase activity	1/1670	69/18639	0.0144927536231884	0.161754751366832	0.998480405252732	0.999999998406233
GO:0016278	lysine N-methyltransferase activity	1/1670	70/18639	0.0142857142857143	0.159443969204448	0.99861706240017	0.999999998406233
GO:0008276	protein methyltransferase activity	2/1670	95/18639	0.0210526315789474	0.23497005988024	0.998638505142165	0.999999998406233
GO:0005244	voltage-gated monoatomic ion channel activity	6/1670	173/18639	0.0346820809248555	0.387089405005019	0.998668807214762	0.999999998406233
GO:0030594	neurotransmitter receptor activity	2/1670	97/18639	0.0206185567010309	0.230125316377554	0.998851116628211	0.999999998406233
GO:0008170	N-methyltransferase activity	2/1670	98/18639	0.0204081632653061	0.227777098863497	0.998944774308805	0.999999998406233
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/1670	73/18639	0.0136986301369863	0.152891477319334	0.998957651083561	0.999999998406233
GO:0031491	nucleosome binding	1/1670	74/18639	0.0135135135135135	0.150825376274478	0.999051409711722	0.999999998406233
GO:0003730	mRNA 3'-UTR binding	11/1670	262/18639	0.0419847328244275	0.46859487132605	0.999051709841187	0.999999998406233
GO:0005261	monoatomic cation channel activity	16/1670	341/18639	0.0469208211143695	0.523686936976487	0.9991067399484	0.999999998406233
GO:0022843	voltage-gated monoatomic cation channel activity	3/1670	143/18639	0.020979020979021	0.234148486244295	0.999838493451223	0.999999998406233
GO:0008168	methyltransferase activity	5/1670	204/18639	0.0245098039215686	0.273555829517436	0.999963378537622	0.999999998406233
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	3/1670	167/18639	0.0179640718562874	0.200498404388827	0.99997767730617	0.999999998406233
GO:0016741	transferase activity, transferring one-carbon groups	5/1670	215/18639	0.0232558139534884	0.259559949867706	0.999984222571653	0.999999998406233
GO:0005267	potassium channel activity	1/1670	124/18639	0.00806451612903226	0.0900086922928337	0.999991539365841	0.999999998406233
GO:0015079	potassium ion transmembrane transporter activity	2/1670	160/18639	0.0125	0.139513473053892	0.999995259713427	0.999999998406233
GO:0045182	translation regulator activity	7/1670	356/18639	0.0196629213483146	0.219459395815111	0.999999992742	0.999999998406233
GO:0030371	translation repressor activity	5/1670	329/18639	0.0151975683890578	0.169621243834519	0.999999998406233	0.999999998406233