category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	10/36	82/9376	31.7615176151762	B2M/HLA-DQA2/HLA-B/CTSS/CTSB/HLA-A/HLA-E/HLA-DRA/CD74/LGMN	17.3690793849965
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	8/36	180/9376	11.5753086419753	B2M/HLA-DQA2/HLA-B/NFKBIA/HLA-A/HLA-E/HLA-DRA/CD74	8.89392111021245
Human Diseases	Immune disease	hsa05330	Allograft rejection	5/36	39/9376	33.3903133903134	HLA-DQA2/HLA-B/HLA-A/HLA-E/HLA-DRA	12.5836672175761
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	5/36	44/9376	29.5959595959596	HLA-DQA2/HLA-B/HLA-A/HLA-E/HLA-DRA	11.8033992781034
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	5/36	45/9376	28.9382716049383	HLA-DQA2/HLA-B/HLA-A/HLA-E/HLA-DRA	11.6628622905966
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	8/36	224/9376	9.3015873015873	B2M/HLA-DQA2/HLA-B/NFKBIA/HLA-A/HLA-E/HLA-DRA/ZFP36	7.80711530000552
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	5/36	54/9376	24.1152263374486	HLA-DQA2/HLA-B/HLA-A/HLA-E/HLA-DRA	10.5755735835814
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	5/36	70/9376	18.6031746031746	HLA-DQA2/HLA-B/HLA-A/HLA-E/HLA-DRA	9.1774482246216
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	7/36	205/9376	8.89322493224932	B2M/HLA-DQA2/HLA-B/NFKBIA/HLA-A/HLA-E/HLA-DRA	7.09392370431381
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	6/36	155/9376	10.0817204301075	HLA-DQA2/HLA-B/CTSS/HLA-A/HLA-E/HLA-DRA	7.07796510306367
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	7/36	250/9376	7.29244444444445	CTSS/PSAP/CTSB/CTSD/NPC2/CD68/LGMN	6.2605517885237
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	6/36	214/9376	7.30218068535826	B2M/HLA-B/NFKBIA/HLA-A/HLA-E/CXCR4	5.78983308699083
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	5/36	137/9376	9.50527169505272	NFKBIA/CTSS/CTSB/CTSD/BCL2A1	6.22586130970721
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	6/36	227/9376	6.88399412628488	B2M/HLA-B/NFKBIA/HLA-A/HLA-E/CXCR4	5.57136736321005
Human Diseases	Immune disease	hsa05310	Asthma	3/36	32/9376	24.4166666666667	HLA-DQA2/PRG2/HLA-DRA	8.23753169482163
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	5/36	160/9376	8.13888888888889	HLA-DQA2/HLA-B/HLA-A/HLA-E/HLA-DRA	5.65435187267101
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	4/36	99/9376	10.5230078563412	HLA-DQA2/C1QB/C1QA/HLA-DRA	5.91359274075839
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	5/36	181/9376	7.19459791282996	HLA-DQA2/CTSS/CTSD/HLA-DRA/CD74	5.22444297238637
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	5/36	196/9376	6.64399092970522	HLA-B/NFKBIA/HLA-A/HLA-E/ZFP36	4.95742842588088
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	3/36	50/9376	15.6266666666667	HLA-DQA2/HLA-DRA/CXCR4	6.43792793940678
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	3/36	52/9376	15.025641025641	APOE/APOC1/NPC2	6.29631879612114
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	4/36	133/9376	7.83291562238931	HLA-B/HLA-A/TYROBP/HLA-E	4.92707135889619
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	4/36	143/9376	7.28515928515928	HLA-DQA2/C1QB/C1QA/HLA-DRA	4.70193195589199
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	3/36	78/9376	10.017094017094	HLA-DQA2/NFKBIA/HLA-DRA	4.9645807476353
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	3/36	88/9376	8.87878787878788	C1QB/C1QA/PLAUR	4.61002299071117
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	3/36	93/9376	8.40143369175627	HLA-DQA2/NFKBIA/HLA-DRA	4.4532451361447
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/36	103/9376	7.58576051779935	NFKBIA/C1QB/C1QA	4.17232247297991
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	4/36	205/9376	5.08184281842818	HLA-B/NFKBIA/HLA-A/HLA-E	3.66849820896706
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	3/36	109/9376	7.16819571865443	SPP1/NFKBIA/CXCL9	4.02128879255454
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	3/36	109/9376	7.16819571865443	HLA-DQA2/NFKBIA/HLA-DRA	4.02128879255454
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	5/36	333/9376	3.91057724391058	SPP1/FN1/HLA-B/HLA-A/HLA-E	3.35744132268454
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	3/36	112/9376	6.97619047619048	HLA-DQA2/NFKBIA/HLA-DRA	3.9500047665171
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	2/36	42/9376	12.4021164021164	FTL/FTH1	4.59768981126698
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/36	46/9376	11.3236714975845	FTL/FTH1	4.35748319751897
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	4/36	250/9376	4.16711111111111	HLA-B/HLA-A/HLA-E/CXCR4	3.15105890980505
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	3/36	144/9376	5.42592592592593	NFKBIA/C1QB/C1QA	3.32277504199279
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	3/36	157/9376	4.97664543524416	HLA-B/HLA-A/HLA-E	3.11952334071582
Organismal Systems	Digestive system	hsa04978	Mineral absorption	2/36	61/9376	8.53916211293261	FTL/FTH1	3.66741469057395
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	2/36	66/9376	7.89225589225589	HLA-DQA2/HLA-DRA	3.48836540710921
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	3/36	173/9376	4.51637764932563	HLA-DQA2/NFKBIA/HLA-DRA	2.89812625938772
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	2/36	78/9376	6.67806267806268	C1QB/C1QA	3.12619571249199
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	3/36	193/9376	4.04835924006909	NFKBIA/CXCL9/CXCR4	2.65653754874297
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	3/36	204/9376	3.83006535947712	FN1/TIMP3/PLAUR	2.53713149602138
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	2/36	89/9376	5.85268414481898	SPP1/FN1	2.85563539010323
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	2/36	93/9376	5.60095579450418	FN1/NFKBIA	2.7682723194985
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/36	95/9376	5.48304093567251	HLA-DQA2/HLA-DRA	2.726469045126
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	2/36	100/9376	5.20888888888889	CXCL9/CXCR4	2.62694234618023
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/36	100/9376	5.20888888888889	HLA-DQA2/HLA-DRA	2.62694234618023
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	2/36	105/9376	4.96084656084656	NFKBIA/BCL2A1	2.53386123897669
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	3/36	238/9376	3.28291316526611	NFKBIA/C1QB/C1QA	2.21470427908714
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/36	22/9376	11.8383838383838	AOC1	3.15966206071483
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/36	138/9376	3.77455716586151	FN1/NFKBIA	2.03848580686376
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	2/36	142/9376	3.66823161189358	NFKBIA/TYROBP	1.98900654734395
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	3/36	298/9376	2.62192393736018	CSH1/CXCL9/CXCR4	1.7664728900937
NA	NA	hsa04518	Integrin signaling	2/36	154/9376	3.38239538239538	SPP1/FN1	1.85065340493537
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	2/36	157/9376	3.31776362349611	C1QB/C1QA	1.81819521994026
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	2/36	168/9376	3.1005291005291	FTL/FTH1	1.70554875461048
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	2/36	169/9376	3.08218277449047	CTSB/CTSD	1.69576856566241
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/36	42/9376	6.2010582010582	AOC1	2.09722927353849
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	3/36	362/9376	2.15837937384899	SPP1/FN1/CSH1	1.39543552394118
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/36	187/9376	2.78550207961973	NFKBIA/CTSB	1.53112443833072
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/36	50/9376	5.20888888888889	AOC1	1.8525426188448
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	2/36	203/9376	2.56595511767926	SPP1/FN1	1.40034512272621
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/36	55/9376	4.73535353535354	PSAP	1.72482585444121
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/36	56/9376	4.65079365079365	NFKBIA	1.70112722200581
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/36	65/9376	4.00683760683761	SPP1	1.51019121241035
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	2/36	232/9376	2.24521072796935	FN1/CXCR4	1.19229078630943
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/36	68/9376	3.83006535947712	BCL2A1	1.4540729154377
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/36	69/9376	3.77455716586151	CTSB	1.43607398923578
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/36	70/9376	3.72063492063492	NFKBIA	1.41840813859346
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/36	71/9376	3.66823161189358	NFKBIA	1.40106395851593
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/36	72/9376	3.61728395061728	NFKBIA	1.38403059261844
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/36	73/9376	3.56773211567732	CXCR4	1.36729769945719
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/36	77/9376	3.38239538239538	NFKBIA	1.30318036502664
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/36	78/9376	3.33903133903134	FN1	1.28781067734868
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/36	83/9376	3.13788487282463	NFKBIA	1.21453166580126
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	2/36	275/9376	1.89414141414141	C1QB/C1QA	0.934310976045234
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/36	90/9376	2.89382716049383	NFKBIA	1.12075505472662
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/36	91/9376	2.86202686202686	NFKBIA	1.10810045834265
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/36	93/9376	2.80047789725209	LYZ	1.08329950285231
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	1/36	94/9376	2.77068557919622	NFKBIA	1.07114445901987
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/36	98/9376	2.65759637188209	NR4A2	1.02406634035145
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	1/36	101/9376	2.57865786578658	FN1	0.990273588248922
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	1/36	103/9376	2.52858683926645	FN1	0.968416207078219
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/36	105/9376	2.48042328042328	NFKBIA	0.947067024666948
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/36	106/9376	2.45702306079665	NFKBIA	0.936575820785336
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/36	109/9376	2.38939857288481	NFKBIA	0.90580344145626
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/36	115/9376	2.26473429951691	NR4A2	0.847193715102118
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/36	116/9376	2.24521072796935	CXCR4	0.837779646939483
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/36	119/9376	2.18860877684407	NFKBIA	0.810103917096876
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/36	120/9376	2.17037037037037	NFKBIA	0.801061240787467
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/36	122/9376	2.13479052823315	NFKBIA	0.783239029169927
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/36	122/9376	2.13479052823315	CSH1	0.783239029169927
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/36	125/9376	2.08355555555556	CTSD	0.757138446527047
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/36	130/9376	2.0034188034188	NFKBIA	0.715221263003729
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/36	136/9376	1.91503267973856	NFKBIA	0.667319051603895
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/36	139/9376	1.87370103916867	CTSD	0.644270477466522
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/36	140/9376	1.86031746031746	SPP1	0.636713771407471
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	1/36	154/9376	1.69119769119769	RGS2	0.536924882473679
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/36	156/9376	1.66951566951567	NFKBIA	0.523505242216626
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/36	163/9376	1.59781867757328	NFKBIA	0.477998128922716
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/36	166/9376	1.56894243641232	RGS2	0.459151500184953
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/36	168/9376	1.55026455026455	CSH1	0.446793628411813
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/36	184/9376	1.41545893719807	CXCR4	0.353342160278552
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/36	200/9376	1.30222222222222	NFKBIA	0.268211960380584
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/36	201/9376	1.29574350469873	BCL2A1	0.263131994652821
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	1/36	205/9376	1.27046070460705	CTSD	0.243072713620311
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/36	216/9376	1.20576131687243	NFKBIA	0.189935576785545
NA	NA	hsa04081	Hormone signaling	1/36	219/9376	1.18924403855911	CSH1	0.175926437490969
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/36	226/9376	1.15240904621436	NFKBIA	0.143985204733352
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	1/36	227/9376	1.14733235438081	NFKBIA	0.139504332112655
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	1/36	233/9376	1.11778731521221	FN1	0.113030480518917
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/36	248/9376	1.05017921146953	NFKBIA	0.0497193345758868
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	1/36	253/9376	1.02942468159859	NFKBIA	0.0294555167207152
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/36	254/9376	1.02537182852143	CXCR4	0.0254499563809421
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/36	323/9376	0.806329549363605	TIMP3	-0.219903334349575
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/36	370/9376	0.703903903903904	CSH1	-0.360770503585449
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	1/36	388/9376	0.671248568155785	APOE	-0.410596680933351
NA	NA	hsa04519	Cadherin signaling	1/36	404/9376	0.644664466446645	NFKBIA	-0.453260777773512
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/36	449/9376	0.580054441969809	RGS2	-0.566143917144518