ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	102/2046	175/18639	0.582857142857143	5.30981147884374	1.18418873656163e-52	1.46247308965361e-49
GO:0045296	cadherin binding	86/2046	334/18639	0.25748502994012	2.34568107187385	1.93765700250211e-14	1.19650319904505e-11
GO:0019843	rRNA binding	27/2046	65/18639	0.415384615384615	3.78414166478683	2.33248198490145e-10	7.82432358937177e-08
GO:0009055	electron transfer activity	38/2046	116/18639	0.327586206896552	2.98430073819395	2.53419387510017e-10	7.82432358937177e-08
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	27/2046	68/18639	0.397058823529412	3.61719423839917	7.88517376590562e-10	1.94763792017869e-07
GO:0140104	molecular carrier activity	58/2046	249/18639	0.232931726907631	2.12200120128608	1.90877175607905e-08	3.92888853126272e-06
GO:0048027	mRNA 5'-UTR binding	14/2046	24/18639	0.583333333333333	5.3141495601173	2.38070960582417e-08	4.20025194741835e-06
GO:0022853	active monoatomic ion transmembrane transporter activity	33/2046	118/18639	0.279661016949153	2.54770366320394	2.72572477177587e-07	4.207837616429e-05
GO:0008017	microtubule binding	59/2046	276/18639	0.213768115942029	1.94742126737218	3.53118998259785e-07	4.84557736500927e-05
GO:0031720	haptoglobin binding	8/2046	10/18639	0.8	7.28797653958944	7.63818517506315e-07	9.43315869120299e-05
GO:0015399	primary active transmembrane transporter activity	39/2046	166/18639	0.234939759036145	2.14029431509027	3.09526909281478e-06	0.000347514302693296
GO:0051087	protein-folding chaperone binding	33/2046	134/18639	0.246268656716418	2.24350024073182	5.96729023372474e-06	0.000541140796872477
GO:0004129	cytochrome-c oxidase activity	9/2046	15/18639	0.6	5.46598240469208	6.13438960017382e-06	0.000541140796872477
GO:0055105	ubiquitin-protein transferase inhibitor activity	9/2046	15/18639	0.6	5.46598240469208	6.13438960017382e-06	0.000541140796872477
GO:0003954	NADH dehydrogenase activity	16/2046	44/18639	0.363636363636364	3.31271660890429	8.62682094876942e-06	0.000710274924782016
GO:0003688	DNA replication origin binding	9/2046	16/18639	0.5625	5.12435850439883	1.26507759571737e-05	0.000919041665124086
GO:0016675	oxidoreductase activity, acting on a heme group of donors	9/2046	16/18639	0.5625	5.12435850439883	1.26507759571737e-05	0.000919041665124086
GO:0003697	single-stranded DNA binding	30/2046	121/18639	0.247933884297521	2.25867041516202	1.34823948307796e-05	0.000925042089778488
GO:0015631	tubulin binding	70/2046	385/18639	0.181818181818182	1.65635830445215	1.46506236482209e-05	0.000932452071381265
GO:0008137	NADH dehydrogenase (ubiquinone) activity	15/2046	41/18639	0.365853658536585	3.332916100422	1.51004384029355e-05	0.000932452071381265
GO:0140597	protein carrier chaperone	40/2046	188/18639	0.212765957446809	1.93829163286953	2.88702138359067e-05	0.0016978435279688
GO:0005344	oxygen carrier activity	8/2046	14/18639	0.571428571428571	5.20569752827817	3.39239956384255e-05	0.00190436975515707
GO:0000287	magnesium ion binding	46/2046	230/18639	0.2	1.82199413489736	3.95763652498619e-05	0.00212507874276432
GO:1990948	ubiquitin ligase inhibitor activity	7/2046	11/18639	0.636363636363636	5.79725406558251	4.20263001235069e-05	0.00216260336052212
GO:0015078	proton transmembrane transporter activity	39/2046	185/18639	0.210810810810811	1.92048030435127	4.48334503549873e-05	0.00221477244753637
GO:0016887	ATP hydrolysis activity	72/2046	417/18639	0.172661870503597	1.57294457688981	6.44799349915669e-05	0.00306279691209943
GO:0030515	snoRNA binding	12/2046	32/18639	0.375	3.41623900293255	8.13636904484924e-05	0.00372163547051437
GO:0004601	peroxidase activity	17/2046	57/18639	0.298245614035088	2.71700879765396	8.61116539870741e-05	0.00379813902407273
GO:0003684	damaged DNA binding	20/2046	74/18639	0.27027027027027	2.46215423634778	9.93182981023023e-05	0.00422958959159805
GO:0016829	lyase activity	40/2046	200/18639	0.2	1.82199413489736	0.000122339628254254	0.00494139985182928
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	13/2046	38/18639	0.342105263157895	3.11656891495601	0.00012403513798114	0.00494139985182928
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	17/2046	59/18639	0.288135593220339	2.62490680451315	0.000138226996253377	0.00533469813665378
GO:0140297	DNA-binding transcription factor binding	80/2046	488/18639	0.163934426229508	1.49343781548964	0.000156664827850773	0.00586306249683953
GO:0000217	DNA secondary structure binding	13/2046	39/18639	0.333333333333333	3.0366568914956	0.000167494155640259	0.00608397888869764
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	17/2046	60/18639	0.283333333333333	2.58115835777126	0.000173363017768355	0.00611723791268339
GO:0140713	histone chaperone activity	34/2046	164/18639	0.207317073170732	1.8886524569058	0.000187779946959989	0.0064418954026552
GO:0070182	DNA polymerase binding	9/2046	21/18639	0.428571428571429	3.90427314620863	0.00019471621951568	0.00649931165140175
GO:0000175	3'-5'-RNA exonuclease activity	12/2046	35/18639	0.342857142857143	3.1234185169669	0.000219738040196435	0.00707455536820381
GO:0004532	RNA exonuclease activity	13/2046	40/18639	0.325	2.96074046920821	0.000223407011627489	0.00707455536820381
GO:0055106	ubiquitin-protein transferase regulator activity	12/2046	36/18639	0.333333333333333	3.0366568914956	0.000296943546090141	0.00914572662812755
GO:0003678	DNA helicase activity	19/2046	74/18639	0.256756756756757	2.3390465245304	0.00030362331316051	0.00914572662812755
GO:0140097	catalytic activity, acting on DNA	58/2046	336/18639	0.172619047619048	1.57255446166736	0.000319484543375694	0.00939436693021385
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	16/2046	58/18639	0.275862068965517	2.51309535847912	0.000372605997916364	0.0103376108664838
GO:0017116	single-stranded DNA helicase activity	16/2046	58/18639	0.275862068965517	2.51309535847912	0.000372605997916364	0.0103376108664838
GO:0031625	ubiquitin protein ligase binding	53/2046	302/18639	0.175496688741722	1.59876968790662	0.000376674080155281	0.0103376108664838
GO:0016860	intramolecular oxidoreductase activity	15/2046	53/18639	0.283018867924528	2.57829358711891	0.000416624542268095	0.0111854632543717
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	14/2046	48/18639	0.291666666666667	2.65707478005865	0.00045900162643696	0.012061000184035
GO:0005536	D-glucose binding	6/2046	11/18639	0.545454545454545	4.96907491335644	0.000491686855639997	0.0126506930565707
GO:0097718	disordered domain specific binding	10/2046	28/18639	0.357142857142857	3.25356095517386	0.000504976675928237	0.0127274733626811
GO:0016853	isomerase activity	35/2046	180/18639	0.194444444444444	1.77138318670577	0.00054435224422388	0.0133205400875907
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	7/2046	15/18639	0.466666666666667	4.25131964809384	0.000550078983374191	0.0133205400875907
GO:0051082	unfolded protein binding	26/2046	121/18639	0.214876033057851	1.95751435980708	0.000577733682050938	0.0136279444404106
GO:0044389	ubiquitin-like protein ligase binding	55/2046	322/18639	0.170807453416149	1.55605089160489	0.000584842959790902	0.0136279444404106
GO:0016209	antioxidant activity	20/2046	86/18639	0.232558139534884	2.118597831276	0.000851526194520513	0.0194747194487562
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	6/2046	12/18639	0.5	4.5549853372434	0.000892103931810679	0.0200317882870216
GO:0003713	transcription coactivator activity	45/2046	256/18639	0.17578125	1.60136203262463	0.000965291835159913	0.0212881324361159
GO:0008094	ATP-dependent activity, acting on DNA	38/2046	210/18639	0.180952380952381	1.64847088395476	0.001341263671438	0.0290607128811567
GO:0004386	helicase activity	30/2046	155/18639	0.193548387096774	1.76322013054583	0.00140839980735823	0.0299892027946107
GO:0004535	poly(A)-specific ribonuclease activity	6/2046	13/18639	0.461538461538462	4.20460184976314	0.00150335654138141	0.0302855413106639
GO:0036121	double-stranded DNA helicase activity	13/2046	48/18639	0.270833333333333	2.46728372434018	0.00155141351824238	0.0302855413106639
GO:0022804	active transmembrane transporter activity	71/2046	457/18639	0.155361050328228	1.41533461244762	0.00160802847698404	0.0302855413106639
GO:0004527	exonuclease activity	19/2046	84/18639	0.226190476190476	2.06058860494344	0.00161031147735993	0.0302855413106639
GO:0070034	telomerase RNA binding	8/2046	22/18639	0.363636363636364	3.31271660890429	0.00161211932520034	0.0302855413106639
GO:0140517	protein-RNA adaptor activity	8/2046	22/18639	0.363636363636364	3.31271660890429	0.00161211932520034	0.0302855413106639
GO:0019838	growth factor binding	27/2046	136/18639	0.198529411764706	1.80859711919959	0.0016180082961342	0.0302855413106639
GO:0043021	ribonucleoprotein complex binding	33/2046	177/18639	0.186440677966102	1.69846910880262	0.0016184985639707	0.0302855413106639
GO:0051287	NAD binding	14/2046	54/18639	0.259259259259259	2.36184424894102	0.0016454743149864	0.0303307578956448
GO:0000400	four-way junction DNA binding	7/2046	18/18639	0.388888888888889	3.54276637341153	0.00202150223356077	0.0361819602673558
GO:0098641	cadherin binding involved in cell-cell adhesion	7/2046	18/18639	0.388888888888889	3.54276637341153	0.00202150223356077	0.0361819602673558
GO:0003689	DNA clamp loader activity	30/2046	160/18639	0.1875	1.70811950146628	0.00234771907553682	0.0414204722612567
GO:0050815	phosphoserine residue binding	5/2046	10/18639	0.5	4.5549853372434	0.00248508651576405	0.0426261367634528
GO:0097177	mitochondrial ribosome binding	5/2046	10/18639	0.5	4.5549853372434	0.00248508651576405	0.0426261367634528
GO:0016831	carboxy-lyase activity	10/2046	34/18639	0.294117647058824	2.67940313955494	0.00273078529364143	0.0461989018855776
GO:0016830	carbon-carbon lyase activity	13/2046	51/18639	0.254901960784314	2.32214938761428	0.0028028066475241	0.0467463680877597
GO:0016651	oxidoreductase activity, acting on NAD(P)H	19/2046	88/18639	0.215909090909091	1.96692548653692	0.00283884826443885	0.0467463680877597
GO:0050699	WW domain binding	8/2046	24/18639	0.333333333333333	3.0366568914956	0.00303573311919213	0.0493306631868722
GO:0003727	single-stranded RNA binding	19/2046	89/18639	0.213483146067416	1.94482520017134	0.00324583513917439	0.0520598233361086
GO:0008408	3'-5' exonuclease activity	14/2046	58/18639	0.241379310344828	2.19895843866923	0.00338582051213537	0.0536088247754766
GO:0000510	H3-H4 histone complex chaperone activity	28/2046	151/18639	0.185430463576159	1.6892660853353	0.00378479087454582	0.0559005895677087
GO:0140584	chromatin extrusion motor activity	28/2046	151/18639	0.185430463576159	1.6892660853353	0.00378479087454582	0.0559005895677087
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	28/2046	151/18639	0.185430463576159	1.6892660853353	0.00378479087454582	0.0559005895677087
GO:0140849	ATP-dependent H2AZ histone chaperone activity	28/2046	151/18639	0.185430463576159	1.6892660853353	0.00378479087454582	0.0559005895677087
GO:0140658	ATP-dependent chromatin remodeler activity	29/2046	158/18639	0.183544303797468	1.67208322506403	0.00378856961113002	0.0559005895677087
GO:0016769	transferase activity, transferring nitrogenous groups	9/2046	30/18639	0.3	2.73299120234604	0.00380214536330974	0.0559005895677087
GO:0180051	translation factor activity	18/2046	84/18639	0.214285714285714	1.95213657310431	0.00393613245815366	0.0568661054175765
GO:0061749	forked DNA-dependent helicase activity	12/2046	47/18639	0.25531914893617	2.32594995944344	0.00395990693596079	0.0568661054175765
GO:0048407	platelet-derived growth factor binding	5/2046	11/18639	0.454545454545455	4.14089576113036	0.00414625289920076	0.0571559175984873
GO:0050786	RAGE receptor binding	5/2046	11/18639	0.454545454545455	4.14089576113036	0.00414625289920076	0.0571559175984873
GO:0015616	DNA translocase activity	28/2046	152/18639	0.184210526315789	1.67815249266862	0.00416520856993025	0.0571559175984873
GO:0140674	ATP-dependent histone chaperone activity	28/2046	152/18639	0.184210526315789	1.67815249266862	0.00416520856993025	0.0571559175984873
GO:0061775	cohesin loader activity	28/2046	153/18639	0.183006535947712	1.66718417572308	0.0045773014143478	0.0621205191947201
GO:0009378	four-way junction helicase activity	12/2046	48/18639	0.25	2.2774926686217	0.00476273807520027	0.0629736471794679
GO:0016835	carbon-oxygen lyase activity	17/2046	79/18639	0.215189873417722	1.96037343628197	0.00477568156951411	0.0629736471794679
GO:0019887	protein kinase regulator activity	42/2046	255/18639	0.164705882352941	1.50046575815077	0.00479313589868015	0.0629736471794679
GO:0043539	protein serine/threonine kinase activator activity	16/2046	73/18639	0.219178082191781	1.99670590125738	0.00504639264699569	0.065603104410944
GO:0034450	ubiquitin-ubiquitin ligase activity	6/2046	16/18639	0.375	3.41623900293255	0.00524950741753583	0.0675327256318411
GO:0003712	transcription coregulator activity	73/2046	495/18639	0.147474747474747	1.3434906247223	0.00533000259921966	0.0678613732993431
GO:0060590	ATPase regulator activity	12/2046	49/18639	0.244897959183673	2.23101322640493	0.00569029937451339	0.0717093849747351
GO:0004540	RNA nuclease activity	23/2046	121/18639	0.190082644628099	1.73164731829088	0.00600906941353147	0.0747993133588549
GO:0051059	NF-kappaB binding	9/2046	32/18639	0.28125	2.56217925219941	0.00609506443207432	0.0747993133588549
GO:0030145	manganese ion binding	15/2046	68/18639	0.220588235294118	2.00955235466621	0.00611719080910473	0.0747993133588549
GO:1990247	N6-methyladenosine-containing RNA reader activity	5/2046	12/18639	0.416666666666667	3.7958211143695	0.00647064501876511	0.0783455548840677
GO:0043531	ADP binding	10/2046	38/18639	0.263157894736842	2.39736070381232	0.00655608044444305	0.0786093140668657
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	23/2046	122/18639	0.188524590163934	1.71745348781309	0.00665543939246384	0.0790333427855081
GO:0004518	nuclease activity	35/2046	209/18639	0.167464114832536	1.52559317515329	0.00728277462964083	0.0856593015962516
GO:0042393	histone binding	40/2046	247/18639	0.161943319838057	1.47529889465373	0.00772655844748306	0.0900216951192601
GO:0008135	translation factor activity, RNA binding	17/2046	83/18639	0.204819277108434	1.86589760802742	0.00799571599855828	0.0922870024132662
GO:0051540	metal cluster binding	16/2046	77/18639	0.207792207792208	1.89298091937388	0.00860702981105575	0.098422979783832
GO:0019207	kinase regulator activity	45/2046	287/18639	0.156794425087108	1.42839261446657	0.00888898587144804	0.100714656433379
GO:0019825	oxygen binding	9/2046	34/18639	0.264705882352941	2.41146282559945	0.0093260463721573	0.101351949154521
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	5/2046	13/18639	0.384615384615385	3.50383487480262	0.0095752003171299	0.101351949154521
GO:0005542	folic acid binding	5/2046	13/18639	0.384615384615385	3.50383487480262	0.0095752003171299	0.101351949154521
GO:0043560	insulin receptor substrate binding	5/2046	13/18639	0.384615384615385	3.50383487480262	0.0095752003171299	0.101351949154521
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	5/2046	13/18639	0.384615384615385	3.50383487480262	0.0095752003171299	0.101351949154521
GO:0140666	annealing activity	5/2046	13/18639	0.384615384615385	3.50383487480262	0.0095752003171299	0.101351949154521
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	11/2046	46/18639	0.239130434782609	2.17847124824684	0.00957802095620912	0.101351949154521
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	10/2046	40/18639	0.25	2.2774926686217	0.00960176360411247	0.101351949154521
GO:0043022	ribosome binding	21/2046	112/18639	0.1875	1.70811950146628	0.00981873855804903	0.102763916264327
GO:0045309	protein phosphorylated amino acid binding	13/2046	59/18639	0.220338983050847	2.00728167403947	0.010408262162852	0.107118364759352
GO:0070063	RNA polymerase binding	13/2046	59/18639	0.220338983050847	2.00728167403947	0.010408262162852	0.107118364759352
GO:1990518	single-stranded 3'-5' DNA helicase activity	11/2046	47/18639	0.234042553191489	2.13212079615649	0.0112946669068405	0.115280277933455
GO:0061650	ubiquitin-like protein conjugating enzyme activity	10/2046	41/18639	0.24390243902439	2.221944066948	0.0114795111873748	0.116206527183671
GO:0051219	phosphoprotein binding	18/2046	93/18639	0.193548387096774	1.76322013054583	0.0116735184026664	0.117209717295065
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	13/2046	60/18639	0.216666666666667	1.97382697947214	0.01198689751352	0.119385632493526
GO:0017069	snRNA binding	12/2046	54/18639	0.222222222222222	2.02443792766373	0.0126654750773816	0.124521026776882
GO:0031406	carboxylic acid binding	31/2046	187/18639	0.165775401069519	1.5102090422946	0.0127041695335119	0.124521026776882
GO:0043138	3'-5' DNA helicase activity	11/2046	48/18639	0.229166666666667	2.08770161290323	0.0132365916946255	0.127707244634125
GO:0008301	DNA binding, bending	6/2046	19/18639	0.315789473684211	2.87683284457478	0.0133394611804066	0.127707244634125
GO:0008574	plus-end-directed microtubule motor activity	6/2046	19/18639	0.315789473684211	2.87683284457478	0.0133394611804066	0.127707244634125
GO:0048029	monosaccharide binding	15/2046	74/18639	0.202702702702703	1.84661567726084	0.0134666455287564	0.127933132523186
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	52/2046	349/18639	0.148997134670487	1.3573595274307	0.0138290788881811	0.130373377304608
GO:0003777	microtubule motor activity	14/2046	68/18639	0.205882352941176	1.87558219768846	0.0145681779592563	0.135244135048096
GO:0098632	cell-cell adhesion mediator activity	12/2046	55/18639	0.218181818181818	1.98762996534258	0.0146259223355742	0.135244135048096
GO:0043177	organic acid binding	31/2046	189/18639	0.164021164021164	1.49422799422799	0.0146742624262711	0.135244135048096
GO:0017056	structural constituent of nuclear pore	7/2046	25/18639	0.28	2.5507917888563	0.0153860099575396	0.140753498500454
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	23/2046	132/18639	0.174242424242424	1.58734337509997	0.01680796936236	0.148198087773949
GO:0030170	pyridoxal phosphate binding	12/2046	56/18639	0.214285714285714	1.95213657310431	0.0168082701968452	0.148198087773949
GO:0051536	iron-sulfur cluster binding	15/2046	76/18639	0.197368421052632	1.79802052785924	0.0170439444544501	0.148198087773949
GO:0098631	cell adhesion mediator activity	15/2046	76/18639	0.197368421052632	1.79802052785924	0.0170439444544501	0.148198087773949
GO:0043024	ribosomal small subunit binding	6/2046	20/18639	0.3	2.73299120234604	0.0173232358462083	0.148198087773949
GO:0030165	PDZ domain binding	16/2046	83/18639	0.192771084337349	1.75613892520228	0.0174112277034897	0.148198087773949
GO:0005337	nucleoside transmembrane transporter activity	4/2046	10/18639	0.4	3.64398826979472	0.0176397723909073	0.148198087773949
GO:0005345	purine nucleobase transmembrane transporter activity	4/2046	10/18639	0.4	3.64398826979472	0.0176397723909073	0.148198087773949
GO:0031996	thioesterase binding	4/2046	10/18639	0.4	3.64398826979472	0.0176397723909073	0.148198087773949
GO:0032356	oxidized DNA binding	4/2046	10/18639	0.4	3.64398826979472	0.0176397723909073	0.148198087773949
GO:0033204	ribonuclease P RNA binding	4/2046	10/18639	0.4	3.64398826979472	0.0176397723909073	0.148198087773949
GO:0098505	G-rich strand telomeric DNA binding	4/2046	10/18639	0.4	3.64398826979472	0.0176397723909073	0.148198087773949
GO:0031386	protein tag activity	5/2046	15/18639	0.333333333333333	3.0366568914956	0.0185457385457961	0.153718034255424
GO:0141047	molecular tag activity	5/2046	15/18639	0.333333333333333	3.0366568914956	0.0185457385457961	0.153718034255424
GO:0070279	vitamin B6 binding	12/2046	57/18639	0.210526315789474	1.91788856304985	0.0192268221425851	0.158300835640617
GO:0042162	telomeric DNA binding	9/2046	38/18639	0.236842105263158	2.15762463343109	0.0194456715526164	0.158651321242871
GO:0031369	translation initiation factor binding	8/2046	32/18639	0.25	2.2774926686217	0.0196547790689549	0.158651321242871
GO:0070717	poly-purine tract binding	8/2046	32/18639	0.25	2.2774926686217	0.0196547790689549	0.158651321242871
GO:0003743	translation initiation factor activity	11/2046	51/18639	0.215686274509804	1.96489563567362	0.020585874567049	0.165088020066919
GO:0019842	vitamin binding	25/2046	150/18639	0.166666666666667	1.5183284457478	0.0220099072021428	0.174585904799907
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	6/2046	21/18639	0.285714285714286	2.60284876413909	0.0220529563957778	0.174585904799907
GO:0001671	ATPase activator activity	7/2046	27/18639	0.259259259259259	2.36184424894102	0.0234166216870157	0.184200813907416
GO:0001221	transcription coregulator binding	20/2046	115/18639	0.173913043478261	1.5843427259977	0.0250146071110816	0.190900538857512
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	4/2046	11/18639	0.363636363636364	3.31271660890429	0.0253503549575967	0.190900538857512
GO:0015205	nucleobase transmembrane transporter activity	4/2046	11/18639	0.363636363636364	3.31271660890429	0.0253503549575967	0.190900538857512
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	4/2046	11/18639	0.363636363636364	3.31271660890429	0.0253503549575967	0.190900538857512
GO:0019206	nucleoside kinase activity	4/2046	11/18639	0.363636363636364	3.31271660890429	0.0253503549575967	0.190900538857512
GO:0034511	U3 snoRNA binding	4/2046	11/18639	0.363636363636364	3.31271660890429	0.0253503549575967	0.190900538857512
GO:0045294	alpha-catenin binding	4/2046	11/18639	0.363636363636364	3.31271660890429	0.0253503549575967	0.190900538857512
GO:0048306	calcium-dependent protein binding	15/2046	80/18639	0.1875	1.70811950146628	0.0263286990367695	0.197066323093396
GO:0140098	catalytic activity, acting on RNA	55/2046	387/18639	0.142118863049096	1.29469867466867	0.0272348990925379	0.202621086622195
GO:0008649	rRNA methyltransferase activity	6/2046	22/18639	0.272727272727273	2.48453745667822	0.0275805219663481	0.203963740290059
GO:0090482	vitamin transmembrane transporter activity	8/2046	34/18639	0.235294117647059	2.14352251164395	0.0278855800390189	0.204992210405883
GO:0051537	2 iron, 2 sulfur cluster binding	7/2046	28/18639	0.25	2.2774926686217	0.0283493457169701	0.207168295624012
GO:0005504	fatty acid binding	10/2046	47/18639	0.212765957446809	1.93829163286953	0.0290276068157293	0.20993075624738
GO:0031491	nucleosome binding	14/2046	74/18639	0.189189189189189	1.72350796544345	0.0290673354804064	0.20993075624738
GO:0003925	G protein activity	11/2046	54/18639	0.203703703703704	1.85573476702509	0.0305696088825463	0.218228132774247
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	11/2046	54/18639	0.203703703703704	1.85573476702509	0.0305696088825463	0.218228132774247
GO:0016877	ligase activity, forming carbon-sulfur bonds	9/2046	41/18639	0.219512195121951	1.9997496602532	0.031040591735264	0.220316843638225
GO:0004549	tRNA-specific ribonuclease activity	5/2046	17/18639	0.294117647058824	2.67940313955494	0.0317646447466656	0.224167635783611
GO:0140102	catalytic activity, acting on a rRNA	6/2046	23/18639	0.260869565217391	2.37651408899656	0.0339500008366833	0.236076424504728
GO:0004526	ribonuclease P activity	4/2046	12/18639	0.333333333333333	3.0366568914956	0.0347902099270125	0.236076424504728
GO:0004859	phospholipase inhibitor activity	4/2046	12/18639	0.333333333333333	3.0366568914956	0.0347902099270125	0.236076424504728
GO:0005049	nuclear export signal receptor activity	4/2046	12/18639	0.333333333333333	3.0366568914956	0.0347902099270125	0.236076424504728
GO:0016801	hydrolase activity, acting on ether bonds	4/2046	12/18639	0.333333333333333	3.0366568914956	0.0347902099270125	0.236076424504728
GO:0016803	ether hydrolase activity	4/2046	12/18639	0.333333333333333	3.0366568914956	0.0347902099270125	0.236076424504728
GO:0043047	single-stranded telomeric DNA binding	4/2046	12/18639	0.333333333333333	3.0366568914956	0.0347902099270125	0.236076424504728
GO:0051879	Hsp90 protein binding	9/2046	42/18639	0.214285714285714	1.95213657310431	0.035791118013069	0.241541151618252
GO:0032182	ubiquitin-like protein binding	20/2046	120/18639	0.166666666666667	1.5183284457478	0.0374920705711319	0.251645147583413
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	21/2046	128/18639	0.1640625	1.49460456378299	0.039112418420808	0.261101820268637
GO:0000900	mRNA regulatory element binding translation repressor activity	5/2046	18/18639	0.277777777777778	2.53054740957967	0.0401191713297446	0.264958163594837
GO:0031690	adrenergic receptor binding	5/2046	18/18639	0.277777777777778	2.53054740957967	0.0401191713297446	0.264958163594837
GO:0004712	protein serine/threonine/tyrosine kinase activity	9/2046	43/18639	0.209302325581395	1.9067380481484	0.0410166383163736	0.269196716207934
GO:0005540	hyaluronic acid binding	6/2046	24/18639	0.25	2.2774926686217	0.0411969063670442	0.269196716207934
GO:0016922	nuclear receptor binding	22/2046	137/18639	0.160583941605839	1.4629149988227	0.0435062253983325	0.281894961526694
GO:0015932	nucleobase-containing compound transmembrane transporter activity	11/2046	57/18639	0.192982456140351	1.75806451612903	0.0435967106490677	0.281894961526694
GO:0016741	transferase activity, transferring one-carbon groups	32/2046	215/18639	0.148837209302326	1.35590261201664	0.0458800684548726	0.29147777078136
GO:0019104	DNA N-glycosylase activity	4/2046	13/18639	0.307692307692308	2.80306789984209	0.0459968808647382	0.29147777078136
GO:0019855	calcium channel inhibitor activity	4/2046	13/18639	0.307692307692308	2.80306789984209	0.0459968808647382	0.29147777078136
GO:0004857	enzyme inhibitor activity	57/2046	416/18639	0.137019230769231	1.24824117414843	0.0460228059128464	0.29147777078136
GO:0050660	flavin adenine dinucleotide binding	15/2046	86/18639	0.174418604651163	1.588948373457	0.0466332730775016	0.292972885646158
GO:0030020	extracellular matrix structural constituent conferring tensile strength	9/2046	44/18639	0.204545454545455	1.86340309250866	0.0467333266982131	0.292972885646158
GO:0016878	acid-thiol ligase activity	7/2046	31/18639	0.225806451612903	2.05709015230347	0.0472014823326227	0.294413286266611
GO:0031072	heat shock protein binding	21/2046	131/18639	0.16030534351145	1.46037697835285	0.0484666758762982	0.300785651795117
GO:0008483	transaminase activity	6/2046	25/18639	0.24	2.18639296187683	0.0493477157595194	0.304722144815032
GO:0030295	protein kinase activator activity	22/2046	139/18639	0.158273381294964	1.44186586214899	0.0498522621343854	0.306306187741124
GO:0140142	nucleocytoplasmic carrier activity	7/2046	32/18639	0.21875	1.99280608504399	0.0549145592464497	0.33574000331369
GO:0015101	organic cation transmembrane transporter activity	14/2046	81/18639	0.172839506172839	1.57456283262735	0.0568520174598833	0.345873111147566
GO:0008143	poly(A) binding	6/2046	26/18639	0.230769230769231	2.10230092488157	0.0584196182838883	0.353523934699284
GO:0061665	SUMO ligase activity	4/2046	14/18639	0.285714285714286	2.60284876413909	0.0589683648162368	0.353523934699284
GO:0098847	sequence-specific single stranded DNA binding	4/2046	14/18639	0.285714285714286	2.60284876413909	0.0589683648162368	0.353523934699284
GO:0001098	basal transcription machinery binding	11/2046	60/18639	0.183333333333333	1.67016129032258	0.0600001523143591	0.356244534914063
GO:0001099	basal RNA polymerase II transcription machinery binding	11/2046	60/18639	0.183333333333333	1.67016129032258	0.0600001523143591	0.356244534914063
GO:0030742	GTP-dependent protein binding	5/2046	20/18639	0.25	2.2774926686217	0.0604700594191796	0.356244534914063
GO:0020037	heme binding	22/2046	142/18639	0.154929577464789	1.41140390731486	0.0605759937910552	0.356244534914063
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	14/2046	82/18639	0.170731707317073	1.5553608468636	0.0619315557294677	0.362490385430771
GO:0140311	protein sequestering activity	7/2046	33/18639	0.212121212121212	1.93241802186084	0.0633673091748578	0.368886507555324
GO:0003725	double-stranded RNA binding	13/2046	75/18639	0.173333333333333	1.57906158357771	0.063621721545979	0.368886507555324
GO:0004177	aminopeptidase activity	8/2046	40/18639	0.2	1.82199413489736	0.0659332351037307	0.373543355224987
GO:0015036	disulfide oxidoreductase activity	8/2046	40/18639	0.2	1.82199413489736	0.0659332351037307	0.373543355224987
GO:0071949	FAD binding	8/2046	40/18639	0.2	1.82199413489736	0.0659332351037307	0.373543355224987
GO:0016836	hydro-lyase activity	11/2046	61/18639	0.180327868852459	1.6427815970386	0.0662614204076394	0.373543355224987
GO:0050661	NADP binding	10/2046	54/18639	0.185185185185185	1.68703160638645	0.0669538690096922	0.373543355224987
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	25/2046	167/18639	0.149700598802395	1.36376806504293	0.0670360229980781	0.373543355224987
GO:0016874	ligase activity	25/2046	167/18639	0.149700598802395	1.36376806504293	0.0670360229980781	0.373543355224987
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	14/2046	83/18639	0.168674698795181	1.53662155955199	0.0673071031670924	0.373543355224987
GO:0044325	transmembrane transporter binding	21/2046	136/18639	0.154411764705882	1.40668664826634	0.0674495289191676	0.373543355224987
GO:0140789	histone phosphatase activity	21/2046	136/18639	0.154411764705882	1.40668664826634	0.0674495289191676	0.373543355224987
GO:0019200	carbohydrate kinase activity	5/2046	21/18639	0.238095238095238	2.16904063678257	0.0724754041139926	0.392152433308995
GO:0051010	microtubule plus-end binding	5/2046	21/18639	0.238095238095238	2.16904063678257	0.0724754041139926	0.392152433308995
GO:0140312	cargo adaptor activity	5/2046	21/18639	0.238095238095238	2.16904063678257	0.0724754041139926	0.392152433308995
GO:0015035	protein-disulfide reductase activity	7/2046	34/18639	0.205882352941176	1.87558219768846	0.0725662759878531	0.392152433308995
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	7/2046	34/18639	0.205882352941176	1.87558219768846	0.0725662759878531	0.392152433308995
GO:0000774	adenyl-nucleotide exchange factor activity	4/2046	15/18639	0.266666666666667	2.42932551319648	0.0736675016418516	0.392152433308995
GO:0004467	long-chain fatty acid-CoA ligase activity	4/2046	15/18639	0.266666666666667	2.42932551319648	0.0736675016418516	0.392152433308995
GO:0061578	K63-linked deubiquitinase activity	4/2046	15/18639	0.266666666666667	2.42932551319648	0.0736675016418516	0.392152433308995
GO:0140776	protein-containing complex destabilizing activity	4/2046	15/18639	0.266666666666667	2.42932551319648	0.0736675016418516	0.392152433308995
GO:0140313	molecular sequestering activity	10/2046	55/18639	0.181818181818182	1.65635830445215	0.0741534997853374	0.393045374398677
GO:0017124	SH3 domain binding	18/2046	115/18639	0.156521739130435	1.42590845339793	0.0771339487842046	0.407095840805524
GO:0097110	scaffold protein binding	12/2046	70/18639	0.171428571428571	1.56170925848345	0.0778525740521686	0.409140123210333
GO:0043130	ubiquitin binding	16/2046	100/18639	0.16	1.45759530791789	0.0785238467078991	0.410919282560404
GO:0061631	ubiquitin conjugating enzyme activity	7/2046	35/18639	0.2	1.82199413489736	0.0825122637477077	0.429546542760713
GO:0016763	pentosyltransferase activity	9/2046	49/18639	0.183673469387755	1.6732599198037	0.0830771034429307	0.429546542760713
GO:0031492	nucleosomal DNA binding	8/2046	42/18639	0.19047619047619	1.73523250942606	0.0834746317915556	0.429546542760713
GO:0043175	RNA polymerase core enzyme binding	8/2046	42/18639	0.19047619047619	1.73523250942606	0.0834746317915556	0.429546542760713
GO:0004620	phospholipase activity	17/2046	109/18639	0.155963302752294	1.4208211143695	0.0862231770644525	0.43261926115512
GO:0019209	kinase activator activity	22/2046	148/18639	0.148648648648649	1.35418482999128	0.086641767357198	0.43261926115512
GO:0001094	TFIID-class transcription factor complex binding	3/2046	10/18639	0.3	2.73299120234604	0.087948359094215	0.43261926115512
GO:0015658	branched-chain amino acid transmembrane transporter activity	3/2046	10/18639	0.3	2.73299120234604	0.087948359094215	0.43261926115512
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/2046	10/18639	0.3	2.73299120234604	0.087948359094215	0.43261926115512
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	3/2046	10/18639	0.3	2.73299120234604	0.087948359094215	0.43261926115512
GO:0030957	Tat protein binding	3/2046	10/18639	0.3	2.73299120234604	0.087948359094215	0.43261926115512
GO:0031957	very long-chain fatty acid-CoA ligase activity	3/2046	10/18639	0.3	2.73299120234604	0.087948359094215	0.43261926115512
GO:0043121	neurotrophin binding	3/2046	10/18639	0.3	2.73299120234604	0.087948359094215	0.43261926115512
GO:0140999	histone H3K4 trimethyltransferase activity	3/2046	10/18639	0.3	2.73299120234604	0.087948359094215	0.43261926115512
GO:0016504	peptidase activator activity	10/2046	57/18639	0.175438596491228	1.59824046920821	0.0899509930998937	0.43261926115512
GO:0005324	long-chain fatty acid transmembrane transporter activity	4/2046	16/18639	0.25	2.2774926686217	0.0900268421998914	0.43261926115512
GO:0005521	lamin binding	4/2046	16/18639	0.25	2.2774926686217	0.0900268421998914	0.43261926115512
GO:0008142	oxysterol binding	4/2046	16/18639	0.25	2.2774926686217	0.0900268421998914	0.43261926115512
GO:0017070	U6 snRNA binding	4/2046	16/18639	0.25	2.2774926686217	0.0900268421998914	0.43261926115512
GO:0043023	ribosomal large subunit binding	4/2046	16/18639	0.25	2.2774926686217	0.0900268421998914	0.43261926115512
GO:0055102	lipase inhibitor activity	4/2046	16/18639	0.25	2.2774926686217	0.0900268421998914	0.43261926115512
GO:0003785	actin monomer binding	6/2046	29/18639	0.206896551724138	1.88482151885934	0.0911948992124153	0.436533722974158
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	8/2046	43/18639	0.186046511627907	1.6948782650208	0.0931793160144543	0.444310638138421
GO:0004722	protein serine/threonine phosphatase activity	16/2046	103/18639	0.155339805825243	1.41514107564844	0.0964908889268813	0.458331722402686
GO:0004602	glutathione peroxidase activity	5/2046	23/18639	0.217391304347826	1.98042840749713	0.100049164655007	0.463413357796829
GO:0017134	fibroblast growth factor binding	5/2046	23/18639	0.217391304347826	1.98042840749713	0.100049164655007	0.463413357796829
GO:0004519	endonuclease activity	19/2046	127/18639	0.149606299212598	1.36290899854527	0.100462446689965	0.463413357796829
GO:0030544	Hsp70 protein binding	9/2046	51/18639	0.176470588235294	1.60764188373297	0.101333098571816	0.463413357796829
GO:0004721	phosphoprotein phosphatase activity	25/2046	175/18639	0.142857142857143	1.30142438206954	0.102233075365992	0.463413357796829
GO:0033192	calmodulin-dependent protein phosphatase activity	13/2046	81/18639	0.160493827160494	1.46209405886825	0.103219981654151	0.463413357796829
GO:0140791	histone H2AXS140 phosphatase activity	13/2046	81/18639	0.160493827160494	1.46209405886825	0.103219981654151	0.463413357796829
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	13/2046	81/18639	0.160493827160494	1.46209405886825	0.103219981654151	0.463413357796829
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	13/2046	81/18639	0.160493827160494	1.46209405886825	0.103219981654151	0.463413357796829
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	13/2046	81/18639	0.160493827160494	1.46209405886825	0.103219981654151	0.463413357796829
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	13/2046	81/18639	0.160493827160494	1.46209405886825	0.103219981654151	0.463413357796829
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	13/2046	81/18639	0.160493827160494	1.46209405886825	0.103219981654151	0.463413357796829
GO:1990439	MAP kinase serine/threonine phosphatase activity	13/2046	81/18639	0.160493827160494	1.46209405886825	0.103219981654151	0.463413357796829
GO:0008187	poly-pyrimidine tract binding	6/2046	30/18639	0.2	1.82199413489736	0.103939676202204	0.463413357796829
GO:0043995	histone H4K5 acetyltransferase activity	6/2046	30/18639	0.2	1.82199413489736	0.103939676202204	0.463413357796829
GO:0043996	histone H4K8 acetyltransferase activity	6/2046	30/18639	0.2	1.82199413489736	0.103939676202204	0.463413357796829
GO:0043997	histone H4K12 acetyltransferase activity	6/2046	30/18639	0.2	1.82199413489736	0.103939676202204	0.463413357796829
GO:0046906	tetrapyrrole binding	22/2046	152/18639	0.144736842105263	1.31854838709677	0.107608834595947	0.469648205280297
GO:0031489	myosin V binding	4/2046	17/18639	0.235294117647059	2.14352251164395	0.107953672185499	0.469648205280297
GO:1990226	histone methyltransferase binding	4/2046	17/18639	0.235294117647059	2.14352251164395	0.107953672185499	0.469648205280297
GO:0033549	MAP kinase phosphatase activity	13/2046	82/18639	0.158536585365854	1.4442636435162	0.110998960451555	0.469648205280297
GO:0005114	type II transforming growth factor beta receptor binding	3/2046	11/18639	0.272727272727273	2.48453745667822	0.111422610645447	0.469648205280297
GO:0005225	volume-sensitive anion channel activity	3/2046	11/18639	0.272727272727273	2.48453745667822	0.111422610645447	0.469648205280297
GO:0008526	phosphatidylinositol transfer activity	3/2046	11/18639	0.272727272727273	2.48453745667822	0.111422610645447	0.469648205280297
GO:0010854	adenylate cyclase regulator activity	3/2046	11/18639	0.272727272727273	2.48453745667822	0.111422610645447	0.469648205280297
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	3/2046	11/18639	0.272727272727273	2.48453745667822	0.111422610645447	0.469648205280297
GO:0015173	aromatic amino acid transmembrane transporter activity	3/2046	11/18639	0.272727272727273	2.48453745667822	0.111422610645447	0.469648205280297
GO:0034056	estrogen response element binding	3/2046	11/18639	0.272727272727273	2.48453745667822	0.111422610645447	0.469648205280297
GO:0035252	UDP-xylosyltransferase activity	3/2046	11/18639	0.272727272727273	2.48453745667822	0.111422610645447	0.469648205280297
GO:0042285	xylosyltransferase activity	3/2046	11/18639	0.272727272727273	2.48453745667822	0.111422610645447	0.469648205280297
GO:0047676	arachidonate-CoA ligase activity	3/2046	11/18639	0.272727272727273	2.48453745667822	0.111422610645447	0.469648205280297
GO:0048185	activin binding	3/2046	11/18639	0.272727272727273	2.48453745667822	0.111422610645447	0.469648205280297
GO:0070990	snRNP binding	3/2046	11/18639	0.272727272727273	2.48453745667822	0.111422610645447	0.469648205280297
GO:0003774	cytoskeletal motor activity	22/2046	153/18639	0.143790849673203	1.30993042378242	0.113308552219697	0.475972999970498
GO:0008170	N-methyltransferase activity	15/2046	98/18639	0.153061224489796	1.39438326650308	0.115392897864825	0.477216395627163
GO:0004622	lysophospholipase activity	5/2046	24/18639	0.208333333333333	1.89791055718475	0.115536601046576	0.477216395627163
GO:0015295	solute:proton symporter activity	5/2046	24/18639	0.208333333333333	1.89791055718475	0.115536601046576	0.477216395627163
GO:0070300	phosphatidic acid binding	5/2046	24/18639	0.208333333333333	1.89791055718475	0.115536601046576	0.477216395627163
GO:0140033	acetylation-dependent protein binding	5/2046	24/18639	0.208333333333333	1.89791055718475	0.115536601046576	0.477216395627163
GO:0044183	protein folding chaperone	12/2046	75/18639	0.16	1.45759530791789	0.116224331233202	0.478456830243347
GO:0008327	methyl-CpG binding	6/2046	31/18639	0.193548387096774	1.76322013054583	0.117556842730903	0.482334554062011
GO:1901505	carbohydrate derivative transmembrane transporter activity	9/2046	53/18639	0.169811320754717	1.54697615227134	0.121693329803901	0.497653186449728
GO:0008234	cysteine-type peptidase activity	26/2046	187/18639	0.13903743315508	1.2666269386987	0.12287390485817	0.500822681517622
GO:0030276	clathrin binding	8/2046	46/18639	0.173913043478261	1.5843427259977	0.125952917454381	0.506546696599084
GO:0030291	protein serine/threonine kinase inhibitor activity	8/2046	46/18639	0.173913043478261	1.5843427259977	0.125952917454381	0.506546696599084
GO:0008168	methyltransferase activity	28/2046	204/18639	0.137254901960784	1.25038813179231	0.126511078794697	0.506546696599084
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	10/2046	61/18639	0.163934426229508	1.49343781548964	0.127111122265332	0.506546696599084
GO:0035615	clathrin adaptor activity	4/2046	18/18639	0.222222222222222	2.02443792766373	0.127334958144286	0.506546696599084
GO:0070628	proteasome binding	4/2046	18/18639	0.222222222222222	2.02443792766373	0.127334958144286	0.506546696599084
GO:1901611	phosphatidylglycerol binding	4/2046	18/18639	0.222222222222222	2.02443792766373	0.127334958144286	0.506546696599084
GO:0017018	myosin phosphatase activity	13/2046	84/18639	0.154761904761905	1.40987641390867	0.127559532503899	0.506546696599084
GO:0002039	p53 binding	11/2046	69/18639	0.159420289855072	1.4523141654979	0.131154056735143	0.51135899882414
GO:0008378	galactosyltransferase activity	6/2046	32/18639	0.1875	1.70811950146628	0.132012754304239	0.51135899882414
GO:0008139	nuclear localization sequence binding	5/2046	25/18639	0.2	1.82199413489736	0.132083822368341	0.51135899882414
GO:0015645	fatty acid ligase activity	5/2046	25/18639	0.2	1.82199413489736	0.132083822368341	0.51135899882414
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	5/2046	25/18639	0.2	1.82199413489736	0.132083822368341	0.51135899882414
GO:0017025	TBP-class protein binding	5/2046	25/18639	0.2	1.82199413489736	0.132083822368341	0.51135899882414
GO:0042974	nuclear retinoic acid receptor binding	5/2046	25/18639	0.2	1.82199413489736	0.132083822368341	0.51135899882414
GO:0120515	fatty acid-CoA ligase activity	5/2046	25/18639	0.2	1.82199413489736	0.132083822368341	0.51135899882414
GO:0140463	chromatin-protein adaptor activity	9/2046	54/18639	0.166666666666667	1.5183284457478	0.132641221962743	0.51191221601246
GO:0003724	RNA helicase activity	12/2046	77/18639	0.155844155844156	1.41973568953041	0.134150079933201	0.515713198504722
GO:0010853	cyclase activator activity	3/2046	12/18639	0.25	2.2774926686217	0.136966744218258	0.515713198504722
GO:0016208	AMP binding	3/2046	12/18639	0.25	2.2774926686217	0.136966744218258	0.515713198504722
GO:0031543	peptidyl-proline dioxygenase activity	3/2046	12/18639	0.25	2.2774926686217	0.136966744218258	0.515713198504722
GO:0070008	serine-type exopeptidase activity	3/2046	12/18639	0.25	2.2774926686217	0.136966744218258	0.515713198504722
GO:0070679	inositol 1,4,5 trisphosphate binding	3/2046	12/18639	0.25	2.2774926686217	0.136966744218258	0.515713198504722
GO:0097371	MDM2/MDM4 family protein binding	3/2046	12/18639	0.25	2.2774926686217	0.136966744218258	0.515713198504722
GO:0097677	STAT family protein binding	3/2046	12/18639	0.25	2.2774926686217	0.136966744218258	0.515713198504722
GO:0140938	histone H3 methyltransferase activity	8/2046	47/18639	0.170212765957447	1.55063330629563	0.138054901369972	0.518230404838649
GO:0030331	nuclear estrogen receptor binding	7/2046	40/18639	0.175	1.59424486803519	0.143091470603618	0.530684583169573
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	7/2046	40/18639	0.175	1.59424486803519	0.143091470603618	0.530684583169573
GO:0050997	quaternary ammonium group binding	7/2046	40/18639	0.175	1.59424486803519	0.143091470603618	0.530684583169573
GO:0140662	ATP-dependent protein folding chaperone	7/2046	40/18639	0.175	1.59424486803519	0.143091470603618	0.530684583169573
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	6/2046	33/18639	0.181818181818182	1.65635830445215	0.147267297666323	0.534596301449815
GO:0140416	transcription regulator inhibitor activity	6/2046	33/18639	0.181818181818182	1.65635830445215	0.147267297666323	0.534596301449815
GO:0003756	protein disulfide isomerase activity	4/2046	19/18639	0.210526315789474	1.91788856304985	0.148042052709179	0.534596301449815
GO:0005229	intracellularly calcium-gated chloride channel activity	4/2046	19/18639	0.210526315789474	1.91788856304985	0.148042052709179	0.534596301449815
GO:0015245	fatty acid transmembrane transporter activity	4/2046	19/18639	0.210526315789474	1.91788856304985	0.148042052709179	0.534596301449815
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	4/2046	19/18639	0.210526315789474	1.91788856304985	0.148042052709179	0.534596301449815
GO:0042800	histone H3K4 methyltransferase activity	4/2046	19/18639	0.210526315789474	1.91788856304985	0.148042052709179	0.534596301449815
GO:0046624	sphingolipid transporter activity	4/2046	19/18639	0.210526315789474	1.91788856304985	0.148042052709179	0.534596301449815
GO:0141147	intracellularly calcium-gated channel activity	4/2046	19/18639	0.210526315789474	1.91788856304985	0.148042052709179	0.534596301449815
GO:0004529	DNA exonuclease activity	5/2046	26/18639	0.192307692307692	1.75191743740131	0.149622918578924	0.535606679550643
GO:0070006	metalloaminopeptidase activity	5/2046	26/18639	0.192307692307692	1.75191743740131	0.149622918578924	0.535606679550643
GO:0120014	phospholipid transfer activity	5/2046	26/18639	0.192307692307692	1.75191743740131	0.149622918578924	0.535606679550643
GO:0140693	molecular condensate scaffold activity	8/2046	48/18639	0.166666666666667	1.5183284457478	0.150715996682093	0.537960277174524
GO:0008186	ATP-dependent activity, acting on RNA	12/2046	79/18639	0.151898734177215	1.3837930138461	0.153494566583469	0.544729280835012
GO:0033293	monocarboxylic acid binding	12/2046	79/18639	0.151898734177215	1.3837930138461	0.153494566583469	0.544729280835012
GO:0042826	histone deacetylase binding	18/2046	127/18639	0.141732283464567	1.29117694599026	0.155090522491385	0.548816032311922
GO:0015175	neutral L-amino acid transmembrane transporter activity	7/2046	41/18639	0.170731707317073	1.5553608468636	0.157235467369963	0.554816577719727
GO:0008514	organic anion transmembrane transporter activity	35/2046	269/18639	0.130111524163569	1.18531216954289	0.163846716278942	0.567716777549714
GO:0001222	transcription corepressor binding	8/2046	49/18639	0.163265306122449	1.48734215093662	0.163913829509247	0.567716777549714
GO:0005338	nucleotide-sugar transmembrane transporter activity	3/2046	13/18639	0.230769230769231	2.10230092488157	0.164257703224314	0.567716777549714
GO:0045159	myosin II binding	3/2046	13/18639	0.230769230769231	2.10230092488157	0.164257703224314	0.567716777549714
GO:0046975	histone H3K36 methyltransferase activity	3/2046	13/18639	0.230769230769231	2.10230092488157	0.164257703224314	0.567716777549714
GO:0071837	HMG box domain binding	3/2046	13/18639	0.230769230769231	2.10230092488157	0.164257703224314	0.567716777549714
GO:0097157	pre-mRNA intronic binding	3/2046	13/18639	0.230769230769231	2.10230092488157	0.164257703224314	0.567716777549714
GO:0004197	cysteine-type endopeptidase activity	13/2046	88/18639	0.147727272727273	1.34579112236737	0.164568912034654	0.567716777549714
GO:0008266	poly(U) RNA binding	5/2046	27/18639	0.185185185185185	1.68703160638645	0.168078019516311	0.573415342824984
GO:0016405	CoA-ligase activity	5/2046	27/18639	0.185185185185185	1.68703160638645	0.168078019516311	0.573415342824984
GO:0023026	MHC class II protein complex binding	5/2046	27/18639	0.185185185185185	1.68703160638645	0.168078019516311	0.573415342824984
GO:0035255	ionotropic glutamate receptor binding	5/2046	27/18639	0.185185185185185	1.68703160638645	0.168078019516311	0.573415342824984
GO:0005326	neurotransmitter transmembrane transporter activity	4/2046	20/18639	0.2	1.82199413489736	0.169935051031679	0.576565351714627
GO:0140664	ATP-dependent DNA damage sensor activity	4/2046	20/18639	0.2	1.82199413489736	0.169935051031679	0.576565351714627
GO:0004521	RNA endonuclease activity	11/2046	73/18639	0.150684931506849	1.37273530711445	0.173176131256394	0.585952115346978
GO:0001618	virus receptor activity	12/2046	81/18639	0.148148148148148	1.34962528510916	0.174194558115422	0.587787648285647
GO:0010485	histone H4 acetyltransferase activity	6/2046	35/18639	0.171428571428571	1.56170925848345	0.179984120635297	0.605668634835399
GO:0019210	kinase inhibitor activity	13/2046	90/18639	0.144444444444444	1.31588465298143	0.184911414879283	0.619267452824497
GO:0140272	exogenous protein binding	12/2046	82/18639	0.146341463414634	1.3331664401688	0.185028089143514	0.619267452824497
GO:0008200	ion channel inhibitor activity	7/2046	43/18639	0.162790697674419	1.4830184818932	0.187311474188376	0.62037044661315
GO:0019789	SUMO transferase activity	5/2046	28/18639	0.178571428571429	1.62678047758693	0.18736694460462	0.62037044661315
GO:0036408	histone H3K14 acetyltransferase activity	5/2046	28/18639	0.178571428571429	1.62678047758693	0.18736694460462	0.62037044661315
GO:0046966	nuclear thyroid hormone receptor binding	5/2046	28/18639	0.178571428571429	1.62678047758693	0.18736694460462	0.62037044661315
GO:0005048	signal sequence binding	8/2046	51/18639	0.156862745098039	1.42901500776264	0.191816819085839	0.620629237003844
GO:0035613	RNA stem-loop binding	4/2046	21/18639	0.19047619047619	1.73523250942606	0.19286673265937	0.620629237003844
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	4/2046	21/18639	0.19047619047619	1.73523250942606	0.19286673265937	0.620629237003844
GO:0072542	protein phosphatase activator activity	4/2046	21/18639	0.19047619047619	1.73523250942606	0.19286673265937	0.620629237003844
GO:0008474	palmitoyl-(protein) hydrolase activity	3/2046	14/18639	0.214285714285714	1.95213657310431	0.192972977335608	0.620629237003844
GO:0015926	glucosidase activity	3/2046	14/18639	0.214285714285714	1.95213657310431	0.192972977335608	0.620629237003844
GO:0032036	myosin heavy chain binding	3/2046	14/18639	0.214285714285714	1.95213657310431	0.192972977335608	0.620629237003844
GO:0044548	S100 protein binding	3/2046	14/18639	0.214285714285714	1.95213657310431	0.192972977335608	0.620629237003844
GO:0071933	Arp2/3 complex binding	3/2046	14/18639	0.214285714285714	1.95213657310431	0.192972977335608	0.620629237003844
GO:0098599	palmitoyl hydrolase activity	3/2046	14/18639	0.214285714285714	1.95213657310431	0.192972977335608	0.620629237003844
GO:1990825	sequence-specific mRNA binding	3/2046	14/18639	0.214285714285714	1.95213657310431	0.192972977335608	0.620629237003844
GO:0036002	pre-mRNA binding	9/2046	59/18639	0.152542372881356	1.38965654356578	0.194471253003065	0.623823370022819
GO:0008173	RNA methyltransferase activity	10/2046	67/18639	0.149253731343284	1.35969711559505	0.195855927884733	0.626637489475765
GO:0000993	RNA polymerase II complex binding	6/2046	36/18639	0.166666666666667	1.5183284457478	0.197340859374127	0.629757006013041
GO:0001046	core promoter sequence-specific DNA binding	7/2046	44/18639	0.159090909090909	1.44931351639563	0.203167576634411	0.641718560469305
GO:0001223	transcription coactivator binding	7/2046	44/18639	0.159090909090909	1.44931351639563	0.203167576634411	0.641718560469305
GO:0016248	channel inhibitor activity	7/2046	44/18639	0.159090909090909	1.44931351639563	0.203167576634411	0.641718560469305
GO:0019205	nucleobase-containing compound kinase activity	7/2046	44/18639	0.159090909090909	1.44931351639563	0.203167576634411	0.641718560469305
GO:0005080	protein kinase C binding	8/2046	52/18639	0.153846153846154	1.40153394992105	0.206464642456802	0.645819425363348
GO:0010484	histone H3 acetyltransferase activity	5/2046	29/18639	0.172413793103448	1.57068459904945	0.207402787394662	0.645819425363348
GO:0035250	UDP-galactosyltransferase activity	5/2046	29/18639	0.172413793103448	1.57068459904945	0.207402787394662	0.645819425363348
GO:0043236	laminin binding	5/2046	29/18639	0.172413793103448	1.57068459904945	0.207402787394662	0.645819425363348
GO:0004860	protein kinase inhibitor activity	12/2046	84/18639	0.142857142857143	1.30142438206954	0.207603491392105	0.645819425363348
GO:0051117	ATPase binding	12/2046	84/18639	0.142857142857143	1.30142438206954	0.207603491392105	0.645819425363348
GO:1990841	promoter-specific chromatin binding	10/2046	68/18639	0.147058823529412	1.33970156977747	0.208656789200415	0.647465162468623
GO:0061134	peptidase regulator activity	29/2046	226/18639	0.128318584070796	1.16897853787663	0.211586404005763	0.654910298113075
GO:0022829	wide pore channel activity	6/2046	37/18639	0.162162162162162	1.47729254180867	0.215286747211027	0.664697832014045
GO:0046972	histone H4K16 acetyltransferase activity	4/2046	22/18639	0.181818181818182	1.65635830445215	0.216686055202288	0.665689746703547
GO:0061133	endopeptidase activator activity	4/2046	22/18639	0.181818181818182	1.65635830445215	0.216686055202288	0.665689746703547
GO:0004674	protein serine/threonine kinase activity	53/2046	433/18639	0.122401847575058	1.11507724191178	0.217429718055987	0.666316877913507
GO:0008009	chemokine activity	7/2046	45/18639	0.155555555555556	1.41710654936461	0.219514075852153	0.66938242883311
GO:0141110	transporter inhibitor activity	7/2046	45/18639	0.155555555555556	1.41710654936461	0.219514075852153	0.66938242883311
GO:0034212	protein N-acetyltransferase activity	8/2046	53/18639	0.150943396226415	1.37508991313008	0.22153509803954	0.669482220510762
GO:0004559	alpha-mannosidase activity	3/2046	15/18639	0.2	1.82199413489736	0.222799346259047	0.669482220510762
GO:0010181	FMN binding	3/2046	15/18639	0.2	1.82199413489736	0.222799346259047	0.669482220510762
GO:0016846	carbon-sulfur lyase activity	3/2046	15/18639	0.2	1.82199413489736	0.222799346259047	0.669482220510762
GO:0042809	nuclear vitamin D receptor binding	3/2046	15/18639	0.2	1.82199413489736	0.222799346259047	0.669482220510762
GO:0048531	beta-1,3-galactosyltransferase activity	3/2046	15/18639	0.2	1.82199413489736	0.222799346259047	0.669482220510762
GO:0019903	protein phosphatase binding	19/2046	144/18639	0.131944444444444	1.20201001955034	0.230428306669047	0.690725628000662
GO:0042887	amide transmembrane transporter activity	6/2046	38/18639	0.157894736842105	1.43841642228739	0.233761125623168	0.699019346597125
GO:0008028	monocarboxylic acid transmembrane transporter activity	10/2046	70/18639	0.142857142857143	1.30142438206954	0.235243049591678	0.701751609289185
GO:0008276	protein methyltransferase activity	13/2046	95/18639	0.136842105263158	1.2466275659824	0.240511010630032	0.714467313470309
GO:0003887	DNA-directed DNA polymerase activity	4/2046	23/18639	0.173913043478261	1.5843427259977	0.241241190054347	0.714467313470309
GO:0070577	lysine-acetylated histone binding	4/2046	23/18639	0.173913043478261	1.5843427259977	0.241241190054347	0.714467313470309
GO:0005200	structural constituent of cytoskeleton	15/2046	112/18639	0.133928571428571	1.2200853581902	0.24495848711886	0.72374098466936
GO:0046943	carboxylic acid transmembrane transporter activity	24/2046	188/18639	0.127659574468085	1.16297497972172	0.24576259081538	0.724383770064425
GO:0072349	modified amino acid transmembrane transporter activity	5/2046	31/18639	0.161290322580645	1.46935010878819	0.249352826345125	0.726389863441741
GO:1901682	sulfur compound transmembrane transporter activity	9/2046	63/18639	0.142857142857143	1.30142438206954	0.251193957927445	0.726389863441741
GO:0004708	MAP kinase kinase activity	3/2046	16/18639	0.1875	1.70811950146628	0.253439154888083	0.726389863441741
GO:0005159	insulin-like growth factor receptor binding	3/2046	16/18639	0.1875	1.70811950146628	0.253439154888083	0.726389863441741
GO:0008296	3'-5'-DNA exonuclease activity	3/2046	16/18639	0.1875	1.70811950146628	0.253439154888083	0.726389863441741
GO:0015562	efflux transmembrane transporter activity	3/2046	16/18639	0.1875	1.70811950146628	0.253439154888083	0.726389863441741
GO:0015923	mannosidase activity	3/2046	16/18639	0.1875	1.70811950146628	0.253439154888083	0.726389863441741
GO:0030275	LRR domain binding	3/2046	16/18639	0.1875	1.70811950146628	0.253439154888083	0.726389863441741
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3/2046	16/18639	0.1875	1.70811950146628	0.253439154888083	0.726389863441741
GO:0097027	ubiquitin-protein transferase activator activity	3/2046	16/18639	0.1875	1.70811950146628	0.253439154888083	0.726389863441741
GO:0001784	phosphotyrosine residue binding	7/2046	47/18639	0.148936170212766	1.35680414300867	0.253501239792219	0.726389863441741
GO:0061733	protein-lysine-acetyltransferase activity	7/2046	47/18639	0.148936170212766	1.35680414300867	0.253501239792219	0.726389863441741
GO:0005342	organic acid transmembrane transporter activity	24/2046	189/18639	0.126984126984127	1.15682167295071	0.254168482747884	0.726615917114901
GO:0016298	lipase activity	17/2046	130/18639	0.130769230769231	1.19130385743289	0.257938324735393	0.735690140988938
GO:0019902	phosphatase binding	24/2046	190/18639	0.126315789473684	1.15073313782991	0.26269017491953	0.744302948420901
GO:0140030	modification-dependent protein binding	22/2046	173/18639	0.127167630057803	1.15849338057058	0.263469678758446	0.744302948420901
GO:0001091	RNA polymerase II general transcription initiation factor binding	4/2046	24/18639	0.166666666666667	1.5183284457478	0.266382107855901	0.744302948420901
GO:0042625	ATPase-coupled ion transmembrane transporter activity	4/2046	24/18639	0.166666666666667	1.5183284457478	0.266382107855901	0.744302948420901
GO:0043998	histone H2A acetyltransferase activity	4/2046	24/18639	0.166666666666667	1.5183284457478	0.266382107855901	0.744302948420901
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	4/2046	24/18639	0.166666666666667	1.5183284457478	0.266382107855901	0.744302948420901
GO:0046961	proton-transporting ATPase activity, rotational mechanism	4/2046	24/18639	0.166666666666667	1.5183284457478	0.266382107855901	0.744302948420901
GO:0050431	transforming growth factor beta binding	4/2046	24/18639	0.166666666666667	1.5183284457478	0.266382107855901	0.744302948420901
GO:0140612	DNA damage sensor activity	4/2046	24/18639	0.166666666666667	1.5183284457478	0.266382107855901	0.744302948420901
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	5/2046	32/18639	0.15625	1.42343291788856	0.271082469315659	0.750643160548967
GO:0042910	xenobiotic transmembrane transporter activity	5/2046	32/18639	0.15625	1.42343291788856	0.271082469315659	0.750643160548967
GO:0071813	lipoprotein particle binding	5/2046	32/18639	0.15625	1.42343291788856	0.271082469315659	0.750643160548967
GO:0071814	protein-lipid complex binding	5/2046	32/18639	0.15625	1.42343291788856	0.271082469315659	0.750643160548967
GO:0038024	cargo receptor activity	9/2046	65/18639	0.138461538461538	1.26138055492894	0.281413907917678	0.769144529763681
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/2046	17/18639	0.176470588235294	1.60764188373297	0.284614615467208	0.769144529763681
GO:0004659	prenyltransferase activity	3/2046	17/18639	0.176470588235294	1.60764188373297	0.284614615467208	0.769144529763681
GO:0005092	GDP-dissociation inhibitor activity	3/2046	17/18639	0.176470588235294	1.60764188373297	0.284614615467208	0.769144529763681
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	3/2046	17/18639	0.176470588235294	1.60764188373297	0.284614615467208	0.769144529763681
GO:0030169	low-density lipoprotein particle binding	3/2046	17/18639	0.176470588235294	1.60764188373297	0.284614615467208	0.769144529763681
GO:0032183	SUMO binding	3/2046	17/18639	0.176470588235294	1.60764188373297	0.284614615467208	0.769144529763681
GO:0032977	membrane insertase activity	3/2046	17/18639	0.176470588235294	1.60764188373297	0.284614615467208	0.769144529763681
GO:0036041	long-chain fatty acid binding	3/2046	17/18639	0.176470588235294	1.60764188373297	0.284614615467208	0.769144529763681
GO:0046965	nuclear retinoid X receptor binding	3/2046	17/18639	0.176470588235294	1.60764188373297	0.284614615467208	0.769144529763681
GO:0048038	quinone binding	3/2046	17/18639	0.176470588235294	1.60764188373297	0.284614615467208	0.769144529763681
GO:0035064	methylated histone binding	10/2046	74/18639	0.135135135135135	1.23107711817389	0.291733074110815	0.770324881025036
GO:0019211	phosphatase activator activity	4/2046	25/18639	0.16	1.45759530791789	0.291962733663056	0.770324881025036
GO:0051020	GTPase binding	38/2046	315/18639	0.120634920634921	1.09898058930317	0.292000116441643	0.770324881025036
GO:0072341	modified amino acid binding	12/2046	91/18639	0.131868131868132	1.20131481421804	0.294650956912828	0.770324881025036
GO:1990782	protein tyrosine kinase binding	15/2046	117/18639	0.128205128205128	1.16794495826754	0.301442052161564	0.770324881025036
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0004862	cAMP-dependent protein kinase inhibitor activity	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0008190	eukaryotic initiation factor 4E binding	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0008239	dipeptidyl-peptidase activity	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0015187	glycine transmembrane transporter activity	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0016783	sulfurtransferase activity	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0016868	intramolecular phosphotransferase activity	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0019911	structural constituent of myelin sheath	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0035374	chondroitin sulfate binding	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0042975	peroxisome proliferator activated receptor binding	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0047429	nucleoside triphosphate diphosphatase activity	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0051880	G-quadruplex DNA binding	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/2046	10/18639	0.2	1.82199413489736	0.301892503980662	0.770324881025036
GO:0106310	protein serine kinase activity	43/2046	361/18639	0.119113573407202	1.08512116067294	0.306935517996509	0.780188991341712
GO:0015605	organophosphate ester transmembrane transporter activity	7/2046	50/18639	0.14	1.27539589442815	0.307021740722325	0.780188991341712
GO:0005085	guanyl-nucleotide exchange factor activity	28/2046	230/18639	0.121739130434783	1.10903990819839	0.308963880853058	0.78351210031525
GO:0003714	transcription corepressor activity	25/2046	204/18639	0.122549019607843	1.11641797481456	0.309759710549972	0.783829569198322
GO:0004402	histone acetyltransferase activity	6/2046	42/18639	0.142857142857143	1.30142438206954	0.311682461422751	0.783829569198322
GO:0035198	miRNA binding	6/2046	42/18639	0.142857142857143	1.30142438206954	0.311682461422751	0.783829569198322
GO:0042054	histone methyltransferase activity	9/2046	67/18639	0.134328358208955	1.22372740403554	0.312565597180183	0.783829569198322
GO:0031267	small GTPase binding	34/2046	283/18639	0.120141342756184	1.0944841093023	0.313703035689843	0.783829569198322
GO:0008376	acetylgalactosaminyltransferase activity	5/2046	34/18639	0.147058823529412	1.33970156977747	0.315591918282334	0.783829569198322
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	5/2046	34/18639	0.147058823529412	1.33970156977747	0.315591918282334	0.783829569198322
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	3/2046	18/18639	0.166666666666667	1.5183284457478	0.316070546931793	0.783829569198322
GO:0008409	5'-3' exonuclease activity	3/2046	18/18639	0.166666666666667	1.5183284457478	0.316070546931793	0.783829569198322
GO:0008525	phosphatidylcholine transporter activity	3/2046	18/18639	0.166666666666667	1.5183284457478	0.316070546931793	0.783829569198322
GO:0070064	proline-rich region binding	3/2046	18/18639	0.166666666666667	1.5183284457478	0.316070546931793	0.783829569198322
GO:0005160	transforming growth factor beta receptor binding	4/2046	26/18639	0.153846153846154	1.40153394992105	0.317842700041988	0.78395444930049
GO:0097602	cullin family protein binding	4/2046	26/18639	0.153846153846154	1.40153394992105	0.317842700041988	0.78395444930049
GO:0019783	ubiquitin-like protein peptidase activity	16/2046	127/18639	0.125984251968504	1.14771284088023	0.31802524623445	0.78395444930049
GO:1901681	sulfur compound binding	33/2046	275/18639	0.12	1.09319648093842	0.319534740271149	0.786106382937985
GO:0042578	phosphoric ester hydrolase activity	43/2046	363/18639	0.118457300275482	1.07914253168852	0.320349435974053	0.786543843793153
GO:0140034	methylation-dependent protein binding	10/2046	76/18639	0.131578947368421	1.19868035190616	0.321257012651737	0.787207163938284
GO:0002020	protease binding	17/2046	136/18639	0.125	1.13874633431085	0.322377126166966	0.78838762537862
GO:0003779	actin binding	52/2046	443/18639	0.117381489841986	1.06934193018807	0.323830135832446	0.790375924413184
GO:0016597	amino acid binding	7/2046	51/18639	0.137254901960784	1.25038813179231	0.325349796437221	0.792518734911179
GO:0008238	exopeptidase activity	13/2046	102/18639	0.127450980392157	1.16107469380714	0.327217808014378	0.793555656509561
GO:0005506	iron ion binding	19/2046	154/18639	0.123376623376623	1.12395742087824	0.329883467640494	0.793555656509561
GO:0048156	tau protein binding	6/2046	43/18639	0.13953488372093	1.2711586987656	0.33185072962292	0.793555656509561
GO:0016410	N-acyltransferase activity	12/2046	94/18639	0.127659574468085	1.16297497972172	0.334799837330313	0.793555656509561
GO:0005539	glycosaminoglycan binding	29/2046	242/18639	0.119834710743802	1.09169070066164	0.336325821471714	0.793555656509561
GO:0005154	epidermal growth factor receptor binding	5/2046	35/18639	0.142857142857143	1.30142438206954	0.338193217890174	0.793555656509561
GO:0016229	steroid dehydrogenase activity	5/2046	35/18639	0.142857142857143	1.30142438206954	0.338193217890174	0.793555656509561
GO:0035591	signaling adaptor activity	16/2046	129/18639	0.124031007751938	1.1299188433472	0.341096833850323	0.793555656509561
GO:0004364	glutathione transferase activity	4/2046	27/18639	0.148148148148148	1.34962528510916	0.343888731437759	0.793555656509561
GO:0004683	calcium/calmodulin-dependent protein kinase activity	4/2046	27/18639	0.148148148148148	1.34962528510916	0.343888731437759	0.793555656509561
GO:0008320	protein transmembrane transporter activity	4/2046	27/18639	0.148148148148148	1.34962528510916	0.343888731437759	0.793555656509561
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	4/2046	27/18639	0.148148148148148	1.34962528510916	0.343888731437759	0.793555656509561
GO:0000099	sulfur amino acid transmembrane transporter activity	2/2046	11/18639	0.181818181818182	1.65635830445215	0.344219146944043	0.793555656509561
GO:0002162	dystroglycan binding	2/2046	11/18639	0.181818181818182	1.65635830445215	0.344219146944043	0.793555656509561
GO:0004523	RNA-DNA hybrid ribonuclease activity	2/2046	11/18639	0.181818181818182	1.65635830445215	0.344219146944043	0.793555656509561
GO:0008199	ferric iron binding	2/2046	11/18639	0.181818181818182	1.65635830445215	0.344219146944043	0.793555656509561
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/2046	11/18639	0.181818181818182	1.65635830445215	0.344219146944043	0.793555656509561
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/2046	11/18639	0.181818181818182	1.65635830445215	0.344219146944043	0.793555656509561
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/2046	11/18639	0.181818181818182	1.65635830445215	0.344219146944043	0.793555656509561
GO:0019107	myristoyltransferase activity	2/2046	11/18639	0.181818181818182	1.65635830445215	0.344219146944043	0.793555656509561
GO:0019215	intermediate filament binding	2/2046	11/18639	0.181818181818182	1.65635830445215	0.344219146944043	0.793555656509561
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/2046	11/18639	0.181818181818182	1.65635830445215	0.344219146944043	0.793555656509561
GO:0032404	mismatch repair complex binding	2/2046	11/18639	0.181818181818182	1.65635830445215	0.344219146944043	0.793555656509561
GO:0032794	GTPase activating protein binding	2/2046	11/18639	0.181818181818182	1.65635830445215	0.344219146944043	0.793555656509561
GO:0034713	type I transforming growth factor beta receptor binding	2/2046	11/18639	0.181818181818182	1.65635830445215	0.344219146944043	0.793555656509561
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/2046	11/18639	0.181818181818182	1.65635830445215	0.344219146944043	0.793555656509561
GO:0043522	leucine zipper domain binding	2/2046	11/18639	0.181818181818182	1.65635830445215	0.344219146944043	0.793555656509561
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/2046	11/18639	0.181818181818182	1.65635830445215	0.344219146944043	0.793555656509561
GO:0016279	protein-lysine N-methyltransferase activity	9/2046	69/18639	0.130434782608696	1.18825704449828	0.344409580477024	0.793555656509561
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	3/2046	19/18639	0.157894736842105	1.43841642228739	0.347575889598533	0.794918932692942
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/2046	19/18639	0.157894736842105	1.43841642228739	0.347575889598533	0.794918932692942
GO:0050145	nucleoside monophosphate kinase activity	3/2046	19/18639	0.157894736842105	1.43841642228739	0.347575889598533	0.794918932692942
GO:0097001	ceramide binding	3/2046	19/18639	0.157894736842105	1.43841642228739	0.347575889598533	0.794918932692942
GO:0004867	serine-type endopeptidase inhibitor activity	12/2046	95/18639	0.126315789473684	1.15073313782991	0.348431956853246	0.795403820173305
GO:0016790	thiolester hydrolase activity	6/2046	44/18639	0.136363636363636	1.24226872833911	0.352169122200054	0.802451782134808
GO:0008081	phosphoric diester hydrolase activity	11/2046	87/18639	0.126436781609195	1.15183537263626	0.357198912897269	0.810927671377344
GO:0016278	lysine N-methyltransferase activity	9/2046	70/18639	0.128571428571429	1.17128194386259	0.360516117820764	0.810927671377344
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	5/2046	36/18639	0.138888888888889	1.26527370478983	0.360911340231472	0.810927671377344
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	5/2046	36/18639	0.138888888888889	1.26527370478983	0.360911340231472	0.810927671377344
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	5/2046	36/18639	0.138888888888889	1.26527370478983	0.360911340231472	0.810927671377344
GO:0004896	cytokine receptor activity	12/2046	96/18639	0.125	1.13874633431085	0.362158189613516	0.810927671377344
GO:0016407	acetyltransferase activity	12/2046	96/18639	0.125	1.13874633431085	0.362158189613516	0.810927671377344
GO:0005544	calcium-dependent phospholipid binding	7/2046	53/18639	0.132075471698113	1.20320367398882	0.362455121133841	0.810927671377344
GO:0051018	protein kinase A binding	7/2046	53/18639	0.132075471698113	1.20320367398882	0.362455121133841	0.810927671377344
GO:0140296	general transcription initiation factor binding	7/2046	53/18639	0.132075471698113	1.20320367398882	0.362455121133841	0.810927671377344
GO:0061135	endopeptidase regulator activity	22/2046	184/18639	0.119565217391304	1.08923562412342	0.368495161974062	0.812483997467328
GO:0016866	intramolecular transferase activity	4/2046	28/18639	0.142857142857143	1.30142438206954	0.369975695909949	0.812483997467328
GO:0045499	chemorepellent activity	4/2046	28/18639	0.142857142857143	1.30142438206954	0.369975695909949	0.812483997467328
GO:0046625	sphingolipid binding	4/2046	28/18639	0.142857142857143	1.30142438206954	0.369975695909949	0.812483997467328
GO:0046875	ephrin receptor binding	4/2046	28/18639	0.142857142857143	1.30142438206954	0.369975695909949	0.812483997467328
GO:0015179	L-amino acid transmembrane transporter activity	8/2046	62/18639	0.129032258064516	1.17548008703056	0.37038523218961	0.812483997467328
GO:0010851	cyclase regulator activity	3/2046	20/18639	0.15	1.36649560117302	0.378924272875037	0.812483997467328
GO:0015095	magnesium ion transmembrane transporter activity	3/2046	20/18639	0.15	1.36649560117302	0.378924272875037	0.812483997467328
GO:0016004	phospholipase activator activity	3/2046	20/18639	0.15	1.36649560117302	0.378924272875037	0.812483997467328
GO:0016505	peptidase activator activity involved in apoptotic process	3/2046	20/18639	0.15	1.36649560117302	0.378924272875037	0.812483997467328
GO:0031418	L-ascorbic acid binding	3/2046	20/18639	0.15	1.36649560117302	0.378924272875037	0.812483997467328
GO:0061608	nuclear import signal receptor activity	3/2046	20/18639	0.15	1.36649560117302	0.378924272875037	0.812483997467328
GO:0008236	serine-type peptidase activity	23/2046	194/18639	0.118556701030928	1.08004806965565	0.380136899734363	0.812483997467328
GO:0000049	tRNA binding	10/2046	80/18639	0.125	1.13874633431085	0.38187184596148	0.812483997467328
GO:0101005	deubiquitinase activity	14/2046	115/18639	0.121739130434783	1.10903990819839	0.382877468631774	0.812483997467328
GO:0023023	MHC protein complex binding	5/2046	37/18639	0.135135135135135	1.23107711817389	0.383665182890916	0.812483997467328
GO:0000995	RNA polymerase III general transcription initiation factor activity	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:0003995	acyl-CoA dehydrogenase activity	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:0004032	aldose reductase (NADPH) activity	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:0004300	enoyl-CoA hydratase activity	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:0005527	macrolide binding	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:0008179	adenylate cyclase binding	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:0008504	monoamine transmembrane transporter activity	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:0008603	cAMP-dependent protein kinase regulator activity	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:0015132	prostaglandin transmembrane transporter activity	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:0016273	arginine N-methyltransferase activity	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:0016274	protein-arginine N-methyltransferase activity	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:0035197	siRNA binding	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:0045295	gamma-catenin binding	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:1990817	poly(A) RNA polymerase activity	2/2046	12/18639	0.166666666666667	1.5183284457478	0.3856696274892	0.812483997467328
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	11/2046	89/18639	0.123595505617978	1.12595143167814	0.386176604464228	0.812483997467328
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	11/2046	89/18639	0.123595505617978	1.12595143167814	0.386176604464228	0.812483997467328
GO:0004725	protein tyrosine phosphatase activity	12/2046	98/18639	0.122448979591837	1.11550661320247	0.389820022844404	0.81736456402859
GO:0042626	ATPase-coupled transmembrane transporter activity	12/2046	98/18639	0.122448979591837	1.11550661320247	0.389820022844404	0.81736456402859
GO:0019888	protein phosphatase regulator activity	13/2046	107/18639	0.121495327102804	1.10681886699372	0.392943003051911	0.820544280488938
GO:0004629	phospholipase C activity	4/2046	29/18639	0.137931034482759	1.25654767923956	0.395987361272394	0.820544280488938
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	4/2046	29/18639	0.137931034482759	1.25654767923956	0.395987361272394	0.820544280488938
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	4/2046	29/18639	0.137931034482759	1.25654767923956	0.395987361272394	0.820544280488938
GO:0097472	cyclin-dependent protein kinase activity	4/2046	29/18639	0.137931034482759	1.25654767923956	0.395987361272394	0.820544280488938
GO:0099604	ligand-gated calcium channel activity	4/2046	29/18639	0.137931034482759	1.25654767923956	0.395987361272394	0.820544280488938
GO:0106222	lncRNA binding	4/2046	29/18639	0.137931034482759	1.25654767923956	0.395987361272394	0.820544280488938
GO:0005319	lipid transporter activity	21/2046	178/18639	0.117977528089888	1.07477182114732	0.397233351562689	0.821747385561007
GO:0140793	histone H2AXY142 phosphatase activity	11/2046	90/18639	0.122222222222222	1.11344086021505	0.400741021675255	0.827617327372809
GO:0004536	DNA nuclease activity	8/2046	64/18639	0.125	1.13874633431085	0.405086356347156	0.835194741383534
GO:0019208	phosphatase regulator activity	14/2046	117/18639	0.11965811965812	1.0900819610497	0.408452836331723	0.838945823165878
GO:0009931	calcium-dependent protein serine/threonine kinase activity	3/2046	21/18639	0.142857142857143	1.30142438206954	0.409933862910981	0.838945823165878
GO:1904047	S-adenosyl-L-methionine binding	3/2046	21/18639	0.142857142857143	1.30142438206954	0.409933862910981	0.838945823165878
GO:0140359	ABC-type transporter activity	6/2046	47/18639	0.127659574468085	1.16297497972172	0.413435274695664	0.838945823165878
GO:0019955	cytokine binding	17/2046	144/18639	0.118055555555556	1.07548264907136	0.413498982269308	0.838945823165878
GO:0019212	phosphatase inhibitor activity	7/2046	56/18639	0.125	1.13874633431085	0.418557457252515	0.838945823165878
GO:0017171	serine hydrolase activity	23/2046	198/18639	0.116161616161616	1.05822891673332	0.419511959031881	0.838945823165878
GO:0008106	alcohol dehydrogenase (NADP+) activity	4/2046	30/18639	0.133333333333333	1.21466275659824	0.421816892293816	0.838945823165878
GO:0035925	mRNA 3'-UTR AU-rich region binding	4/2046	30/18639	0.133333333333333	1.21466275659824	0.421816892293816	0.838945823165878
GO:0070566	adenylyltransferase activity	4/2046	30/18639	0.133333333333333	1.21466275659824	0.421816892293816	0.838945823165878
GO:0002161	aminoacyl-tRNA editing activity	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0005035	death receptor activity	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0005172	vascular endothelial growth factor receptor binding	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0008035	high-density lipoprotein particle binding	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0015651	quaternary ammonium group transmembrane transporter activity	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0030955	potassium ion binding	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0031432	titin binding	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0031994	insulin-like growth factor I binding	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0035325	Toll-like receptor binding	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0051011	microtubule minus-end binding	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0061459	L-arginine transmembrane transporter activity	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0070123	transforming growth factor beta receptor activity, type III	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0070700	BMP receptor binding	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0071714	icosanoid transmembrane transporter activity	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0140852	histone ubiquitin ligase activity	2/2046	13/18639	0.153846153846154	1.40153394992105	0.425926340991907	0.838945823165878
GO:0008201	heparin binding	20/2046	172/18639	0.116279069767442	1.059298915638	0.427637945128527	0.840728969394524
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	5/2046	39/18639	0.128205128205128	1.16794495826754	0.428977384521423	0.840728969394524
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	5/2046	39/18639	0.128205128205128	1.16794495826754	0.428977384521423	0.840728969394524
GO:0052689	carboxylic ester hydrolase activity	11/2046	92/18639	0.119565217391304	1.08923562412342	0.429918653777137	0.840728969394524
GO:0031490	chromatin DNA binding	15/2046	128/18639	0.1171875	1.06757468841642	0.435098047822428	0.840728969394524
GO:0015293	symporter activity	17/2046	146/18639	0.116438356164384	1.06075001004298	0.436666717623177	0.840728969394524
GO:0051015	actin filament binding	24/2046	209/18639	0.114832535885167	1.04612103439083	0.439568263980236	0.840728969394524
GO:0008093	cytoskeletal anchor activity	3/2046	22/18639	0.136363636363636	1.24226872833911	0.440446674654459	0.840728969394524
GO:0032931	histone H3K56 acetyltransferase activity	3/2046	22/18639	0.136363636363636	1.24226872833911	0.440446674654459	0.840728969394524
GO:0043992	histone H3K9 acetyltransferase activity	3/2046	22/18639	0.136363636363636	1.24226872833911	0.440446674654459	0.840728969394524
GO:0043993	histone H3K18 acetyltransferase activity	3/2046	22/18639	0.136363636363636	1.24226872833911	0.440446674654459	0.840728969394524
GO:0043994	histone H3K23 acetyltransferase activity	3/2046	22/18639	0.136363636363636	1.24226872833911	0.440446674654459	0.840728969394524
GO:0043999	histone H2AK5 acetyltransferase activity	3/2046	22/18639	0.136363636363636	1.24226872833911	0.440446674654459	0.840728969394524
GO:0044012	histone H2AK9 acetyltransferase activity	3/2046	22/18639	0.136363636363636	1.24226872833911	0.440446674654459	0.840728969394524
GO:0044014	histone H2BK5 acetyltransferase activity	3/2046	22/18639	0.136363636363636	1.24226872833911	0.440446674654459	0.840728969394524
GO:0044015	histone H2BK12 acetyltransferase activity	3/2046	22/18639	0.136363636363636	1.24226872833911	0.440446674654459	0.840728969394524
GO:0044016	histone H3K4 acetyltransferase activity	3/2046	22/18639	0.136363636363636	1.24226872833911	0.440446674654459	0.840728969394524
GO:0044017	histone H3K27 acetyltransferase activity	3/2046	22/18639	0.136363636363636	1.24226872833911	0.440446674654459	0.840728969394524
GO:0044018	histone H3K36 acetyltransferase activity	3/2046	22/18639	0.136363636363636	1.24226872833911	0.440446674654459	0.840728969394524
GO:0140908	histone H3K122 acetyltransferase activity	3/2046	22/18639	0.136363636363636	1.24226872833911	0.440446674654459	0.840728969394524
GO:0030695	GTPase regulator activity	55/2046	489/18639	0.112474437627812	1.02463882841876	0.444972893457583	0.848057906512523
GO:0005164	tumor necrosis factor receptor binding	4/2046	31/18639	0.129032258064516	1.17548008703056	0.447367124286215	0.849997536143807
GO:0047499	calcium-independent phospholipase A2 activity	4/2046	31/18639	0.129032258064516	1.17548008703056	0.447367124286215	0.849997536143807
GO:0016791	phosphatase activity	31/2046	273/18639	0.113553113553114	1.03446553446553	0.448956509875508	0.851707050224657
GO:0060589	nucleoside-triphosphatase regulator activity	55/2046	490/18639	0.112244897959184	1.02254772876893	0.451358099965154	0.852407512440541
GO:0061791	GTPase motor activity	5/2046	40/18639	0.125	1.13874633431085	0.451396366911833	0.852407512440541
GO:1990606	membrane scission GTPase motor activity	5/2046	40/18639	0.125	1.13874633431085	0.451396366911833	0.852407512440541
GO:0061980	regulatory RNA binding	7/2046	58/18639	0.120689655172414	1.09947921933461	0.455759835357565	0.852427479739272
GO:0035402	histone H3T11 kinase activity	28/2046	247/18639	0.11336032388664	1.03270922625761	0.458150207913115	0.852427479739272
GO:0140101	catalytic activity, acting on a tRNA	16/2046	139/18639	0.115107913669065	1.04862971792654	0.459845154875955	0.852427479739272
GO:0004705	JUN kinase activity	2/2046	14/18639	0.142857142857143	1.30142438206954	0.46475190160129	0.852427479739272
GO:0008174	mRNA methyltransferase activity	2/2046	14/18639	0.142857142857143	1.30142438206954	0.46475190160129	0.852427479739272
GO:0008494	translation activator activity	2/2046	14/18639	0.142857142857143	1.30142438206954	0.46475190160129	0.852427479739272
GO:0008559	ABC-type xenobiotic transporter activity	2/2046	14/18639	0.142857142857143	1.30142438206954	0.46475190160129	0.852427479739272
GO:0016530	metallochaperone activity	2/2046	14/18639	0.142857142857143	1.30142438206954	0.46475190160129	0.852427479739272
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	2/2046	14/18639	0.142857142857143	1.30142438206954	0.46475190160129	0.852427479739272
GO:0019992	diacylglycerol binding	2/2046	14/18639	0.142857142857143	1.30142438206954	0.46475190160129	0.852427479739272
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/2046	14/18639	0.142857142857143	1.30142438206954	0.46475190160129	0.852427479739272
GO:0030983	mismatched DNA binding	2/2046	14/18639	0.142857142857143	1.30142438206954	0.46475190160129	0.852427479739272
GO:0034236	protein kinase A catalytic subunit binding	2/2046	14/18639	0.142857142857143	1.30142438206954	0.46475190160129	0.852427479739272
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/2046	14/18639	0.142857142857143	1.30142438206954	0.46475190160129	0.852427479739272
GO:0070742	C2H2 zinc finger domain binding	2/2046	14/18639	0.142857142857143	1.30142438206954	0.46475190160129	0.852427479739272
GO:0004679	AMP-activated protein kinase activity	28/2046	248/18639	0.112903225806452	1.02854507615174	0.467109700040904	0.852427479739272
GO:0004252	serine-type endopeptidase activity	20/2046	176/18639	0.113636363636364	1.03522394028259	0.470212324852155	0.852427479739272
GO:0008171	O-methyltransferase activity	3/2046	23/18639	0.130434782608696	1.18825704449828	0.470327497344476	0.852427479739272
GO:0043274	phospholipase binding	3/2046	23/18639	0.130434782608696	1.18825704449828	0.470327497344476	0.852427479739272
GO:0044013	histone H2B acetyltransferase activity	3/2046	23/18639	0.130434782608696	1.18825704449828	0.470327497344476	0.852427479739272
GO:0022884	macromolecule transmembrane transporter activity	4/2046	32/18639	0.125	1.13874633431085	0.472550646424865	0.852427479739272
GO:0043425	bHLH transcription factor binding	4/2046	32/18639	0.125	1.13874633431085	0.472550646424865	0.852427479739272
GO:0047498	calcium-dependent phospholipase A2 activity	4/2046	32/18639	0.125	1.13874633431085	0.472550646424865	0.852427479739272
GO:0004812	aminoacyl-tRNA ligase activity	5/2046	41/18639	0.121951219512195	1.110972033474	0.473572798764228	0.852427479739272
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	5/2046	41/18639	0.121951219512195	1.110972033474	0.473572798764228	0.852427479739272
GO:0016875	ligase activity, forming carbon-oxygen bonds	5/2046	41/18639	0.121951219512195	1.110972033474	0.473572798764228	0.852427479739272
GO:0017080	sodium channel regulator activity	5/2046	41/18639	0.121951219512195	1.110972033474	0.473572798764228	0.852427479739272
GO:0140318	protein transporter activity	5/2046	41/18639	0.121951219512195	1.110972033474	0.473572798764228	0.852427479739272
GO:0032813	tumor necrosis factor receptor superfamily binding	6/2046	50/18639	0.12	1.09319648093842	0.474031656253792	0.852427479739272
GO:0048020	CCR chemokine receptor binding	6/2046	50/18639	0.12	1.09319648093842	0.474031656253792	0.852427479739272
GO:0005548	phospholipid transporter activity	8/2046	68/18639	0.117647058823529	1.07176125582198	0.474154586997112	0.852427479739272
GO:0140223	general transcription initiation factor activity	8/2046	68/18639	0.117647058823529	1.07176125582198	0.474154586997112	0.852427479739272
GO:0004879	nuclear receptor activity	7/2046	59/18639	0.11864406779661	1.08084397832894	0.474184355126218	0.852427479739272
GO:0016757	glycosyltransferase activity	30/2046	267/18639	0.112359550561798	1.02359221061649	0.474999956191415	0.852652537640113
GO:0008080	N-acetyltransferase activity	8/2046	69/18639	0.115942028985507	1.05622848399847	0.491170325557124	0.871926278470633
GO:0005525	GTP binding	42/2046	378/18639	0.111111111111111	1.01221896383187	0.49123407188341	0.871926278470633
GO:0030414	peptidase inhibitor activity	19/2046	169/18639	0.112426035502959	1.02419788648077	0.492350616715906	0.871926278470633
GO:0098531	ligand-modulated transcription factor activity	7/2046	60/18639	0.116666666666667	1.06282991202346	0.492443833677009	0.871926278470633
GO:0004520	DNA endonuclease activity	5/2046	42/18639	0.119047619047619	1.08452031839129	0.495449871377941	0.871926278470633
GO:0016859	cis-trans isomerase activity	5/2046	42/18639	0.119047619047619	1.08452031839129	0.495449871377941	0.871926278470633
GO:0019894	kinesin binding	5/2046	42/18639	0.119047619047619	1.08452031839129	0.495449871377941	0.871926278470633
GO:0042056	chemoattractant activity	5/2046	42/18639	0.119047619047619	1.08452031839129	0.495449871377941	0.871926278470633
GO:0005315	phosphate transmembrane transporter activity	3/2046	24/18639	0.125	1.13874633431085	0.4994625529857	0.871926278470633
GO:0015149	hexose transmembrane transporter activity	3/2046	24/18639	0.125	1.13874633431085	0.4994625529857	0.871926278470633
GO:0030215	semaphorin receptor binding	3/2046	24/18639	0.125	1.13874633431085	0.4994625529857	0.871926278470633
GO:0055056	D-glucose transmembrane transporter activity	3/2046	24/18639	0.125	1.13874633431085	0.4994625529857	0.871926278470633
GO:0060229	lipase activator activity	3/2046	24/18639	0.125	1.13874633431085	0.4994625529857	0.871926278470633
GO:0004089	carbonate dehydratase activity	2/2046	15/18639	0.133333333333333	1.21466275659824	0.501975371653943	0.871926278470633
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/2046	15/18639	0.133333333333333	1.21466275659824	0.501975371653943	0.871926278470633
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/2046	15/18639	0.133333333333333	1.21466275659824	0.501975371653943	0.871926278470633
GO:0005041	low-density lipoprotein particle receptor activity	2/2046	15/18639	0.133333333333333	1.21466275659824	0.501975371653943	0.871926278470633
GO:0008242	omega peptidase activity	2/2046	15/18639	0.133333333333333	1.21466275659824	0.501975371653943	0.871926278470633
GO:0008252	nucleotidase activity	2/2046	15/18639	0.133333333333333	1.21466275659824	0.501975371653943	0.871926278470633
GO:0015929	hexosaminidase activity	2/2046	15/18639	0.133333333333333	1.21466275659824	0.501975371653943	0.871926278470633
GO:0017081	chloride channel regulator activity	2/2046	15/18639	0.133333333333333	1.21466275659824	0.501975371653943	0.871926278470633
GO:0141050	histone H3K deacetylase activity	2/2046	15/18639	0.133333333333333	1.21466275659824	0.501975371653943	0.871926278470633
GO:0141051	histone H4K deacetylase activity	2/2046	15/18639	0.133333333333333	1.21466275659824	0.501975371653943	0.871926278470633
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	27/2046	243/18639	0.111111111111111	1.01221896383187	0.503851623399881	0.873780641102594
GO:0004866	endopeptidase inhibitor activity	18/2046	161/18639	0.111801242236025	1.01850603814138	0.504457973365303	0.873780641102594
GO:0019905	syntaxin binding	7/2046	61/18639	0.114754098360656	1.04540647084275	0.510505550623266	0.878098901744313
GO:0030159	signaling receptor complex adaptor activity	6/2046	52/18639	0.115384615384615	1.05115046244079	0.513422799222907	0.878098901744313
GO:0019001	guanyl nucleotide binding	44/2046	400/18639	0.11	1.00209677419355	0.518271091094874	0.878098901744313
GO:0032561	guanyl ribonucleotide binding	44/2046	400/18639	0.11	1.00209677419355	0.518271091094874	0.878098901744313
GO:0004676	3-phosphoinositide-dependent protein kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:0004711	ribosomal protein S6 kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:0035175	histone H3S10 kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:0035979	histone H2AXS139 kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:0044022	histone H3S28 kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:0044023	histone H4S1 kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:0044024	histone H2AS1 kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:0044025	histone H2BS14 kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:0072354	histone H3T3 kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:0072371	histone H2AS121 kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:0072518	Rho-dependent protein serine/threonine kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:0140823	histone H2BS36 kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:0140855	histone H3S57 kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:0140995	histone H2A kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:0140997	histone H4 kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:0140998	histone H2B kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:1990244	histone H2AT120 kinase activity	27/2046	245/18639	0.110204081632653	1.00395595188222	0.521882262251276	0.878098901744313
GO:0140299	molecular sensor activity	8/2046	71/18639	0.112676056338028	1.02647556895626	0.524704852834738	0.881525197430122
GO:0003707	nuclear steroid receptor activity	3/2046	25/18639	0.12	1.09319648093842	0.527757982893334	0.881525197430122
GO:0047617	fatty acyl-CoA hydrolase activity	3/2046	25/18639	0.12	1.09319648093842	0.527757982893334	0.881525197430122
GO:0004843	cysteine-type deubiquitinase activity	12/2046	108/18639	0.111111111111111	1.01221896383187	0.52779063884265	0.881525197430122
GO:0004677	DNA-dependent protein kinase activity	27/2046	246/18639	0.109756097560976	0.9998748301266	0.530844742280241	0.881525197430122
GO:0140857	histone H3T45 kinase activity	27/2046	246/18639	0.109756097560976	0.9998748301266	0.530844742280241	0.881525197430122
GO:0004864	protein phosphatase inhibitor activity	6/2046	53/18639	0.113207547169811	1.03131743484756	0.532695268766192	0.881525197430122
GO:0005246	calcium channel regulator activity	6/2046	53/18639	0.113207547169811	1.03131743484756	0.532695268766192	0.881525197430122
GO:0016251	RNA polymerase II general transcription initiation factor activity	6/2046	53/18639	0.113207547169811	1.03131743484756	0.532695268766192	0.881525197430122
GO:0016779	nucleotidyltransferase activity	15/2046	136/18639	0.110294117647059	1.0047761773331	0.532951850326904	0.881525197430122
GO:0000062	fatty-acyl-CoA binding	2/2046	16/18639	0.125	1.13874633431085	0.537480545477637	0.881525197430122
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/2046	16/18639	0.125	1.13874633431085	0.537480545477637	0.881525197430122
GO:0004707	MAP kinase activity	2/2046	16/18639	0.125	1.13874633431085	0.537480545477637	0.881525197430122
GO:0005024	transforming growth factor beta receptor activity	2/2046	16/18639	0.125	1.13874633431085	0.537480545477637	0.881525197430122
GO:0016722	oxidoreductase activity, acting on metal ions	2/2046	16/18639	0.125	1.13874633431085	0.537480545477637	0.881525197430122
GO:0022858	alanine transmembrane transporter activity	2/2046	16/18639	0.125	1.13874633431085	0.537480545477637	0.881525197430122
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/2046	16/18639	0.125	1.13874633431085	0.537480545477637	0.881525197430122
GO:0140327	flippase activity	2/2046	16/18639	0.125	1.13874633431085	0.537480545477637	0.881525197430122
GO:0140328	floppase activity	2/2046	16/18639	0.125	1.13874633431085	0.537480545477637	0.881525197430122
GO:0035403	histone H3T6 kinase activity	27/2046	247/18639	0.109311740890688	0.99582675389127	0.539766344225298	0.884100046575918
GO:0042379	chemokine receptor binding	8/2046	72/18639	0.111111111111111	1.01221896383187	0.541174181608919	0.885231939452999
GO:0004623	phospholipase A2 activity	4/2046	35/18639	0.114285714285714	1.04113950565563	0.545170665508933	0.887069528199647
GO:0034061	DNA polymerase activity	4/2046	35/18639	0.114285714285714	1.04113950565563	0.545170665508933	0.887069528199647
GO:0043015	gamma-tubulin binding	4/2046	35/18639	0.114285714285714	1.04113950565563	0.545170665508933	0.887069528199647
GO:0140566	histone reader activity	4/2046	35/18639	0.114285714285714	1.04113950565563	0.545170665508933	0.887069528199647
GO:0005507	copper ion binding	7/2046	63/18639	0.111111111111111	1.01221896383187	0.545916158307525	0.887113757249728
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	6/2046	54/18639	0.111111111111111	1.01221896383187	0.551639591661953	0.891541902360456
GO:0004175	endopeptidase activity	44/2046	405/18639	0.108641975308642	0.989725209080048	0.553334308006779	0.891541902360456
GO:0004435	phosphatidylinositol phospholipase C activity	3/2046	26/18639	0.115384615384615	1.05115046244079	0.555138237178292	0.891541902360456
GO:0005227	calcium-activated cation channel activity	3/2046	26/18639	0.115384615384615	1.05115046244079	0.555138237178292	0.891541902360456
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	3/2046	26/18639	0.115384615384615	1.05115046244079	0.555138237178292	0.891541902360456
GO:0008198	ferrous iron binding	3/2046	26/18639	0.115384615384615	1.05115046244079	0.555138237178292	0.891541902360456
GO:0015145	monosaccharide transmembrane transporter activity	3/2046	26/18639	0.115384615384615	1.05115046244079	0.555138237178292	0.891541902360456
GO:0016289	acyl-CoA hydrolase activity	3/2046	26/18639	0.115384615384615	1.05115046244079	0.555138237178292	0.891541902360456
GO:0034237	protein kinase A regulatory subunit binding	3/2046	26/18639	0.115384615384615	1.05115046244079	0.555138237178292	0.891541902360456
GO:0051539	4 iron, 4 sulfur cluster binding	5/2046	45/18639	0.111111111111111	1.01221896383187	0.558796118129243	0.895088464188865
GO:0140303	intramembrane lipid transporter activity	5/2046	45/18639	0.111111111111111	1.01221896383187	0.558796118129243	0.895088464188865
GO:0035173	histone kinase activity	39/2046	360/18639	0.108333333333333	0.98691348973607	0.560536127559128	0.896712587481247
GO:0043178	alcohol binding	10/2046	92/18639	0.108695652173913	0.990214203748566	0.56267599958389	0.898633201876772
GO:0004033	aldo-keto reductase (NADPH) activity	4/2046	36/18639	0.111111111111111	1.01221896383187	0.568203081168615	0.898633201876772
GO:0005484	SNAP receptor activity	4/2046	36/18639	0.111111111111111	1.01221896383187	0.568203081168615	0.898633201876772
GO:0044390	ubiquitin-like protein conjugating enzyme binding	4/2046	36/18639	0.111111111111111	1.01221896383187	0.568203081168615	0.898633201876772
GO:0008429	phosphatidylethanolamine binding	2/2046	17/18639	0.117647058823529	1.07176125582198	0.571196002812361	0.898633201876772
GO:0015278	intracellularly gated calcium channel activity	2/2046	17/18639	0.117647058823529	1.07176125582198	0.571196002812361	0.898633201876772
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/2046	17/18639	0.117647058823529	1.07176125582198	0.571196002812361	0.898633201876772
GO:0016805	dipeptidase activity	2/2046	17/18639	0.117647058823529	1.07176125582198	0.571196002812361	0.898633201876772
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/2046	17/18639	0.117647058823529	1.07176125582198	0.571196002812361	0.898633201876772
GO:0038191	neuropilin binding	2/2046	17/18639	0.117647058823529	1.07176125582198	0.571196002812361	0.898633201876772
GO:0070402	NADPH binding	2/2046	17/18639	0.117647058823529	1.07176125582198	0.571196002812361	0.898633201876772
GO:0070403	NAD+ binding	2/2046	17/18639	0.117647058823529	1.07176125582198	0.571196002812361	0.898633201876772
GO:1901567	fatty acid derivative binding	2/2046	17/18639	0.117647058823529	1.07176125582198	0.571196002812361	0.898633201876772
GO:0015171	amino acid transmembrane transporter activity	11/2046	102/18639	0.107843137254902	0.982447817836812	0.571948757250861	0.898672665654979
GO:0120013	lipid transfer activity	7/2046	65/18639	0.107692307692308	0.981073764944733	0.580200185458797	0.910479325338773
GO:0005096	GTPase activator activity	29/2046	271/18639	0.107011070110701	0.974867710553938	0.587319474429669	0.920481663604875
GO:0170055	lipid transmembrane transporter activity	6/2046	56/18639	0.107142857142857	0.976068286552157	0.588425530075274	0.921046298660283
GO:0043394	proteoglycan binding	4/2046	37/18639	0.108108108108108	0.984861694539114	0.590571311262882	0.92323489798691
GO:0005179	hormone activity	14/2046	132/18639	0.106060606060606	0.966209010930419	0.595847591101655	0.930305657409032
GO:0043495	protein-membrane adaptor activity	5/2046	47/18639	0.106382978723404	0.969145816434766	0.598724568859718	0.931015069656036
GO:0003746	translation elongation factor activity	2/2046	18/18639	0.111111111111111	1.01221896383187	0.603086684797432	0.931015069656036
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/2046	18/18639	0.111111111111111	1.01221896383187	0.603086684797432	0.931015069656036
GO:0008308	voltage-gated monoatomic anion channel activity	2/2046	18/18639	0.111111111111111	1.01221896383187	0.603086684797432	0.931015069656036
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/2046	18/18639	0.111111111111111	1.01221896383187	0.603086684797432	0.931015069656036
GO:0016854	racemase and epimerase activity	2/2046	18/18639	0.111111111111111	1.01221896383187	0.603086684797432	0.931015069656036
GO:0030228	lipoprotein particle receptor activity	2/2046	18/18639	0.111111111111111	1.01221896383187	0.603086684797432	0.931015069656036
GO:0034185	apolipoprotein binding	2/2046	18/18639	0.111111111111111	1.01221896383187	0.603086684797432	0.931015069656036
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	2/2046	18/18639	0.111111111111111	1.01221896383187	0.603086684797432	0.931015069656036
GO:0017022	myosin binding	8/2046	76/18639	0.105263157894737	0.958944281524927	0.604566733441992	0.931946298641843
GO:0005178	integrin binding	17/2046	161/18639	0.105590062111801	0.961922369355749	0.605199134826525	0.931946298641843
GO:0051119	sugar transmembrane transporter activity	3/2046	28/18639	0.107142857142857	0.976068286552157	0.606932672934168	0.9322908595444
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	3/2046	28/18639	0.107142857142857	0.976068286552157	0.606932672934168	0.9322908595444
GO:0005109	frizzled binding	4/2046	38/18639	0.105263157894737	0.958944281524927	0.612241122136094	0.939276752593884
GO:0035091	phosphatidylinositol binding	30/2046	284/18639	0.105633802816901	0.962320845896493	0.61727916048277	0.943278391774211
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	19/2046	181/18639	0.104972375690608	0.956295264172648	0.617582992641703	0.943278391774211
GO:0016879	ligase activity, forming carbon-nitrogen bonds	5/2046	48/18639	0.104166666666667	0.948955278592375	0.617904630724969	0.943278391774211
GO:0032266	phosphatidylinositol-3-phosphate binding	5/2046	48/18639	0.104166666666667	0.948955278592375	0.617904630724969	0.943278391774211
GO:0003924	GTPase activity	35/2046	331/18639	0.105740181268882	0.963289950474435	0.619875039994983	0.944179096561395
GO:0005126	cytokine receptor binding	29/2046	275/18639	0.105454545454545	0.960687816582245	0.620023682033434	0.944179096561395
GO:0000149	SNARE binding	11/2046	106/18639	0.10377358490566	0.945374315276932	0.624614934671102	0.945567295496603
GO:0004497	monooxygenase activity	11/2046	106/18639	0.10377358490566	0.945374315276932	0.624614934671102	0.945567295496603
GO:0008013	beta-catenin binding	11/2046	106/18639	0.10377358490566	0.945374315276932	0.624614934671102	0.945567295496603
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	24/2046	229/18639	0.104803493449782	0.954756751911281	0.627064226622656	0.945567295496603
GO:0032934	sterol binding	7/2046	68/18639	0.102941176470588	0.93779109884423	0.629132164632216	0.945567295496603
GO:0015294	solute:monoatomic cation symporter activity	12/2046	116/18639	0.103448275862069	0.942410759429669	0.630542784502712	0.945567295496603
GO:0016417	S-acyltransferase activity	3/2046	29/18639	0.103448275862069	0.942410759429669	0.631272516587449	0.945567295496603
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/2046	19/18639	0.105263157894737	0.958944281524927	0.633146778350244	0.945567295496603
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/2046	19/18639	0.105263157894737	0.958944281524927	0.633146778350244	0.945567295496603
GO:0005520	insulin-like growth factor binding	2/2046	19/18639	0.105263157894737	0.958944281524927	0.633146778350244	0.945567295496603
GO:0031420	alkali metal ion binding	2/2046	19/18639	0.105263157894737	0.958944281524927	0.633146778350244	0.945567295496603
GO:0034987	immunoglobulin receptor binding	2/2046	19/18639	0.105263157894737	0.958944281524927	0.633146778350244	0.945567295496603
GO:0046527	glucosyltransferase activity	2/2046	19/18639	0.105263157894737	0.958944281524927	0.633146778350244	0.945567295496603
GO:0120227	acyl-CoA binding	2/2046	19/18639	0.105263157894737	0.958944281524927	0.633146778350244	0.945567295496603
GO:0140036	ubiquitin-modified protein reader activity	2/2046	19/18639	0.105263157894737	0.958944281524927	0.633146778350244	0.945567295496603
GO:0016776	phosphotransferase activity, phosphate group as acceptor	4/2046	39/18639	0.102564102564103	0.934355966614031	0.633185549292057	0.945567295496603
GO:0019199	transmembrane receptor protein kinase activity	8/2046	78/18639	0.102564102564103	0.934355966614031	0.634526509929642	0.946425410341918
GO:0008194	UDP-glycosyltransferase activity	15/2046	145/18639	0.103448275862069	0.942410759429669	0.635977608486576	0.947127809374676
GO:0035254	glutamate receptor binding	5/2046	49/18639	0.102040816326531	0.929588844335388	0.636531240308486	0.947127809374676
GO:0001786	phosphatidylserine binding	6/2046	59/18639	0.101694915254237	0.926437695710522	0.640488821534883	0.951127815872019
GO:0015291	secondary active transmembrane transporter activity	30/2046	287/18639	0.104529616724739	0.952261742977715	0.64075979174536	0.951127815872019
GO:0008237	metallopeptidase activity	19/2046	184/18639	0.103260869565217	0.940703493561137	0.646694249843371	0.954506775580593
GO:0005496	steroid binding	11/2046	108/18639	0.101851851851852	0.927867383512545	0.649670303457749	0.954506775580593
GO:0141003	histone H2AX kinase activity	37/2046	354/18639	0.104519774011299	0.952172076146926	0.650482953328642	0.954506775580593
GO:0001968	fibronectin binding	3/2046	30/18639	0.1	0.91099706744868	0.654545363731186	0.954506775580593
GO:0015215	nucleotide transmembrane transporter activity	3/2046	30/18639	0.1	0.91099706744868	0.654545363731186	0.954506775580593
GO:0022839	monoatomic ion-gated channel activity	3/2046	30/18639	0.1	0.91099706744868	0.654545363731186	0.954506775580593
GO:0031210	phosphatidylcholine binding	3/2046	30/18639	0.1	0.91099706744868	0.654545363731186	0.954506775580593
GO:0033612	receptor serine/threonine kinase binding	3/2046	30/18639	0.1	0.91099706744868	0.654545363731186	0.954506775580593
GO:0051721	protein phosphatase 2A binding	3/2046	30/18639	0.1	0.91099706744868	0.654545363731186	0.954506775580593
GO:0004714	transmembrane receptor protein tyrosine kinase activity	6/2046	60/18639	0.1	0.91099706744868	0.656938264630203	0.954506775580593
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	6/2046	60/18639	0.1	0.91099706744868	0.656938264630203	0.954506775580593
GO:0030246	carbohydrate binding	29/2046	280/18639	0.103571428571429	0.943532677000419	0.659266111291039	0.954506775580593
GO:0000339	RNA cap binding	2/2046	20/18639	0.1	0.91099706744868	0.661393723403045	0.954506775580593
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	2/2046	20/18639	0.1	0.91099706744868	0.661393723403045	0.954506775580593
GO:0042288	MHC class I protein binding	2/2046	20/18639	0.1	0.91099706744868	0.661393723403045	0.954506775580593
GO:0140939	histone H4 methyltransferase activity	2/2046	20/18639	0.1	0.91099706744868	0.661393723403045	0.954506775580593
GO:0019787	ubiquitin-like protein transferase activity	50/2046	479/18639	0.104384133611691	0.950936396084217	0.670530686164459	0.954506775580593
GO:0140996	histone H3 kinase activity	37/2046	357/18639	0.103641456582633	0.944170630128884	0.670880064779715	0.954506775580593
GO:0005010	insulin-like growth factor receptor activity	5/2046	51/18639	0.0980392156862745	0.893134379851647	0.672057493715132	0.954506775580593
GO:0015026	coreceptor activity	6/2046	61/18639	0.0983606557377049	0.896062689293784	0.672912742521868	0.954506775580593
GO:0005201	extracellular matrix structural constituent	17/2046	168/18639	0.101190476190476	0.921842270632593	0.675915006304866	0.954506775580593
GO:0005310	dicarboxylic acid transmembrane transporter activity	3/2046	31/18639	0.0967741935483871	0.881610065272916	0.676743032243147	0.954506775580593
GO:0017147	Wnt-protein binding	3/2046	31/18639	0.0967741935483871	0.881610065272916	0.676743032243147	0.954506775580593
GO:0070273	phosphatidylinositol-4-phosphate binding	3/2046	31/18639	0.0967741935483871	0.881610065272916	0.676743032243147	0.954506775580593
GO:0030971	receptor tyrosine kinase binding	8/2046	81/18639	0.0987654320987654	0.899750190072771	0.676994146208016	0.954506775580593
GO:0016758	hexosyltransferase activity	20/2046	197/18639	0.101522842639594	0.924870119237239	0.678682321960129	0.954506775580593
GO:0016798	hydrolase activity, acting on glycosyl bonds	13/2046	130/18639	0.1	0.91099706744868	0.680936974531737	0.954506775580593
GO:0005516	calmodulin binding	21/2046	207/18639	0.101449275362319	0.924199923498661	0.682594633364906	0.954506775580593
GO:0000182	rDNA binding	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0004090	carbonyl reductase (NADPH) activity	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0004935	adrenergic receptor activity	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0004955	prostaglandin receptor activity	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0005528	FK506 binding	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0015203	polyamine transmembrane transporter activity	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0015279	store-operated calcium channel activity	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0016427	tRNA (cytidine) methyltransferase activity	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0031434	mitogen-activated protein kinase kinase binding	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0032052	bile acid binding	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0043295	glutathione binding	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0050308	sugar-phosphatase activity	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0070097	delta-catenin binding	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0140135	mechanosensitive monoatomic cation channel activity	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0140940	histone H2A methyltransferase activity	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0141109	transporter activator activity	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:1990259	histone H2AQ104 methyltransferase activity	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:1990757	ubiquitin ligase activator activity	1/2046	10/18639	0.1	0.91099706744868	0.68746855863339	0.954506775580593
GO:0001846	opsonin binding	2/2046	21/18639	0.0952380952380952	0.867616254713029	0.687863182402209	0.954506775580593
GO:0008373	sialyltransferase activity	2/2046	21/18639	0.0952380952380952	0.867616254713029	0.687863182402209	0.954506775580593
GO:0015174	basic amino acid transmembrane transporter activity	2/2046	21/18639	0.0952380952380952	0.867616254713029	0.687863182402209	0.954506775580593
GO:0036122	BMP binding	2/2046	21/18639	0.0952380952380952	0.867616254713029	0.687863182402209	0.954506775580593
GO:0051428	peptide hormone receptor binding	2/2046	21/18639	0.0952380952380952	0.867616254713029	0.687863182402209	0.954506775580593
GO:0061891	calcium ion sensor activity	2/2046	21/18639	0.0952380952380952	0.867616254713029	0.687863182402209	0.954506775580593
GO:0008307	structural constituent of muscle	4/2046	42/18639	0.0952380952380952	0.867616254713029	0.691494334959705	0.958468578760085
GO:0015106	bicarbonate transmembrane transporter activity	3/2046	32/18639	0.09375	0.854059750733138	0.697866382500211	0.958510722855775
GO:0005003	ephrin receptor activity	5/2046	53/18639	0.0943396226415094	0.859431195706302	0.705208343406373	0.958510722855775
GO:0005005	transmembrane-ephrin receptor activity	5/2046	53/18639	0.0943396226415094	0.859431195706302	0.705208343406373	0.958510722855775
GO:0005253	monoatomic anion channel activity	10/2046	103/18639	0.0970873786407767	0.884463172280272	0.706239384196607	0.958510722855775
GO:0008375	acetylglucosaminyltransferase activity	4/2046	43/18639	0.0930232558139535	0.8474391325104	0.709393643751424	0.958510722855775
GO:0004407	histone deacetylase activity	2/2046	22/18639	0.0909090909090909	0.828179152226073	0.712604833176984	0.958510722855775
GO:0005243	gap junction channel activity	2/2046	22/18639	0.0909090909090909	0.828179152226073	0.712604833176984	0.958510722855775
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/2046	22/18639	0.0909090909090909	0.828179152226073	0.712604833176984	0.958510722855775
GO:0033558	protein lysine deacetylase activity	2/2046	22/18639	0.0909090909090909	0.828179152226073	0.712604833176984	0.958510722855775
GO:0034062	5'-3' RNA polymerase activity	2/2046	22/18639	0.0909090909090909	0.828179152226073	0.712604833176984	0.958510722855775
GO:0050321	tau-protein kinase activity	2/2046	22/18639	0.0909090909090909	0.828179152226073	0.712604833176984	0.958510722855775
GO:0097747	RNA polymerase activity	2/2046	22/18639	0.0909090909090909	0.828179152226073	0.712604833176984	0.958510722855775
GO:0140035	ubiquitin-like protein reader activity	2/2046	22/18639	0.0909090909090909	0.828179152226073	0.712604833176984	0.958510722855775
GO:0140784	metal ion sensor activity	2/2046	22/18639	0.0909090909090909	0.828179152226073	0.712604833176984	0.958510722855775
GO:0019956	chemokine binding	3/2046	33/18639	0.0909090909090909	0.828179152226073	0.717924048176312	0.958510722855775
GO:0030296	protein tyrosine kinase activator activity	3/2046	33/18639	0.0909090909090909	0.828179152226073	0.717924048176312	0.958510722855775
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0003953	NAD+ nucleosidase activity	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0004016	adenylate cyclase activity	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0004954	prostanoid receptor activity	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0008046	axon guidance receptor activity	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0008271	secondary active sulfate transmembrane transporter activity	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0008432	JUN kinase binding	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0015217	ADP transmembrane transporter activity	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0016594	glycine binding	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0019203	carbohydrate phosphatase activity	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0031731	CCR6 chemokine receptor binding	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0032050	clathrin heavy chain binding	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0097493	structural molecule activity conferring elasticity	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0140031	phosphorylation-dependent protein binding	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0140537	transcription regulator activator activity	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:1900750	oligopeptide binding	1/2046	11/18639	0.0909090909090909	0.828179152226073	0.721793499802325	0.958510722855775
GO:0035401	histone H3Y41 kinase activity	11/2046	115/18639	0.0956521739130435	0.871388499298738	0.729643445201387	0.966855852815142
GO:0140801	histone H2AXY142 kinase activity	11/2046	115/18639	0.0956521739130435	0.871388499298738	0.729643445201387	0.966855852815142
GO:0160215	deacylase activity	6/2046	65/18639	0.0923076923076923	0.840920369952628	0.731907580558917	0.967867204272849
GO:0000295	adenine nucleotide transmembrane transporter activity	2/2046	23/18639	0.0869565217391304	0.792171362998852	0.735678865161032	0.967867204272849
GO:0016493	C-C chemokine receptor activity	2/2046	23/18639	0.0869565217391304	0.792171362998852	0.735678865161032	0.967867204272849
GO:0140103	catalytic activity, acting on a glycoprotein	2/2046	23/18639	0.0869565217391304	0.792171362998852	0.735678865161032	0.967867204272849
GO:0030332	cyclin binding	3/2046	34/18639	0.0882352941176471	0.803820941866483	0.736931268961104	0.967867204272849
GO:0008235	metalloexopeptidase activity	6/2046	66/18639	0.0909090909090909	0.828179152226073	0.745412103389677	0.967867204272849
GO:0000340	RNA 7-methylguanosine cap binding	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0004126	cytidine deaminase activity	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0004875	complement receptor activity	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0005025	transforming growth factor beta receptor activity, type I	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0005026	transforming growth factor beta receptor activity, type II	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0005095	GTPase inhibitor activity	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0005165	neurotrophin receptor binding	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0005247	voltage-gated chloride channel activity	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0005436	sodium:phosphate symporter activity	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0015269	calcium-activated potassium channel activity	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0016361	activin receptor activity, type I	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0016362	activin receptor activity, type II	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0016840	carbon-nitrogen lyase activity	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0017002	activin receptor activity	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0035251	UDP-glucosyltransferase activity	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0035259	nuclear glucocorticoid receptor binding	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0036009	protein-glutamine N-methyltransferase activity	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0042301	phosphate ion binding	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/2046	12/18639	0.0833333333333333	0.7591642228739	0.752350215467154	0.967867204272849
GO:0019957	C-C chemokine binding	2/2046	24/18639	0.0833333333333333	0.7591642228739	0.75715307535879	0.97101147255255
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/2046	24/18639	0.0833333333333333	0.7591642228739	0.75715307535879	0.97101147255255
GO:0070840	dynein complex binding	2/2046	24/18639	0.0833333333333333	0.7591642228739	0.75715307535879	0.97101147255255
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	4/2046	46/18639	0.0869565217391304	0.792171362998852	0.758493001336704	0.971720805654387
GO:0016755	aminoacyltransferase activity	50/2046	496/18639	0.100806451612903	0.918343817992621	0.761574575808775	0.97465761774491
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/2046	36/18639	0.0833333333333333	0.7591642228739	0.771882075022575	0.9770206712666
GO:0016409	palmitoyltransferase activity	3/2046	36/18639	0.0833333333333333	0.7591642228739	0.771882075022575	0.9770206712666
GO:0099095	ligand-gated monoatomic anion channel activity	4/2046	47/18639	0.0851063829787234	0.775316653147813	0.773355181102005	0.9770206712666
GO:0001664	G protein-coupled receptor binding	29/2046	297/18639	0.0976430976430976	0.889525756094671	0.775721910642481	0.9770206712666
GO:0000030	mannosyltransferase activity	2/2046	25/18639	0.08	0.728797653958944	0.777100474703612	0.9770206712666
GO:0001848	complement binding	2/2046	25/18639	0.08	0.728797653958944	0.777100474703612	0.9770206712666
GO:0004709	MAP kinase kinase kinase activity	2/2046	25/18639	0.08	0.728797653958944	0.777100474703612	0.9770206712666
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/2046	25/18639	0.08	0.728797653958944	0.777100474703612	0.9770206712666
GO:0019707	protein-cysteine S-acyltransferase activity	2/2046	25/18639	0.08	0.728797653958944	0.777100474703612	0.9770206712666
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/2046	25/18639	0.08	0.728797653958944	0.777100474703612	0.9770206712666
GO:0004713	protein tyrosine kinase activity	13/2046	140/18639	0.0928571428571429	0.845925848345203	0.777727478169449	0.9770206712666
GO:0046332	SMAD binding	7/2046	79/18639	0.0886075949367089	0.807212591410223	0.77790389017421	0.9770206712666
GO:0099106	ion channel regulator activity	15/2046	160/18639	0.09375	0.854059750733138	0.777927861128734	0.9770206712666
GO:0003964	RNA-directed DNA polymerase activity	1/2046	13/18639	0.0769230769230769	0.700766974960523	0.779552205006758	0.9770206712666
GO:0004465	lipoprotein lipase activity	1/2046	13/18639	0.0769230769230769	0.700766974960523	0.779552205006758	0.9770206712666
GO:0008253	5'-nucleotidase activity	1/2046	13/18639	0.0769230769230769	0.700766974960523	0.779552205006758	0.9770206712666
GO:0009982	pseudouridine synthase activity	1/2046	13/18639	0.0769230769230769	0.700766974960523	0.779552205006758	0.9770206712666
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/2046	13/18639	0.0769230769230769	0.700766974960523	0.779552205006758	0.9770206712666
GO:0046974	histone H3K9 methyltransferase activity	1/2046	13/18639	0.0769230769230769	0.700766974960523	0.779552205006758	0.9770206712666
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/2046	13/18639	0.0769230769230769	0.700766974960523	0.779552205006758	0.9770206712666
GO:0004222	metalloendopeptidase activity	10/2046	110/18639	0.0909090909090909	0.828179152226073	0.780146058851519	0.9770206712666
GO:0019213	deacetylase activity	3/2046	37/18639	0.0810810810810811	0.738646270904336	0.787880083589607	0.9770206712666
GO:0030551	cyclic nucleotide binding	3/2046	37/18639	0.0810810810810811	0.738646270904336	0.787880083589607	0.9770206712666
GO:0031593	polyubiquitin modification-dependent protein binding	5/2046	59/18639	0.0847457627118644	0.772031413092102	0.790234364264445	0.9770206712666
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	8/2046	91/18639	0.0879120879120879	0.800876542812027	0.795068030818462	0.9770206712666
GO:0001637	G protein-coupled chemoattractant receptor activity	2/2046	26/18639	0.0769230769230769	0.700766974960523	0.795597327830722	0.9770206712666
GO:0004950	chemokine receptor activity	2/2046	26/18639	0.0769230769230769	0.700766974960523	0.795597327830722	0.9770206712666
GO:0005112	Notch binding	2/2046	26/18639	0.0769230769230769	0.700766974960523	0.795597327830722	0.9770206712666
GO:0015216	purine nucleotide transmembrane transporter activity	2/2046	26/18639	0.0769230769230769	0.700766974960523	0.795597327830722	0.9770206712666
GO:0043548	phosphatidylinositol 3-kinase binding	2/2046	26/18639	0.0769230769230769	0.700766974960523	0.795597327830722	0.9770206712666
GO:0050681	nuclear androgen receptor binding	2/2046	26/18639	0.0769230769230769	0.700766974960523	0.795597327830722	0.9770206712666
GO:0052742	phosphatidylinositol kinase activity	2/2046	26/18639	0.0769230769230769	0.700766974960523	0.795597327830722	0.9770206712666
GO:0046982	protein heterodimerization activity	36/2046	369/18639	0.0975609756097561	0.8887776267792	0.798401668460947	0.9770206712666
GO:0005004	GPI-linked ephrin receptor activity	4/2046	49/18639	0.0816326530612245	0.74367107546831	0.800905343452287	0.9770206712666
GO:0005008	hepatocyte growth factor receptor activity	4/2046	49/18639	0.0816326530612245	0.74367107546831	0.800905343452287	0.9770206712666
GO:0005009	insulin receptor activity	4/2046	49/18639	0.0816326530612245	0.74367107546831	0.800905343452287	0.9770206712666
GO:0005011	macrophage colony-stimulating factor receptor activity	4/2046	49/18639	0.0816326530612245	0.74367107546831	0.800905343452287	0.9770206712666
GO:0005018	platelet-derived growth factor alpha-receptor activity	4/2046	49/18639	0.0816326530612245	0.74367107546831	0.800905343452287	0.9770206712666
GO:0005020	stem cell factor receptor activity	4/2046	49/18639	0.0816326530612245	0.74367107546831	0.800905343452287	0.9770206712666
GO:0008288	boss receptor activity	4/2046	49/18639	0.0816326530612245	0.74367107546831	0.800905343452287	0.9770206712666
GO:0036332	placental growth factor receptor activity	4/2046	49/18639	0.0816326530612245	0.74367107546831	0.800905343452287	0.9770206712666
GO:0038062	protein tyrosine kinase collagen receptor activity	4/2046	49/18639	0.0816326530612245	0.74367107546831	0.800905343452287	0.9770206712666
GO:0060175	brain-derived neurotrophic factor receptor activity	4/2046	49/18639	0.0816326530612245	0.74367107546831	0.800905343452287	0.9770206712666
GO:0000146	microfilament motor activity	3/2046	38/18639	0.0789473684210526	0.719208211143695	0.802934851714194	0.9770206712666
GO:0004065	arylsulfatase activity	1/2046	14/18639	0.0714285714285714	0.650712191034772	0.803767612961025	0.9770206712666
GO:0005347	ATP transmembrane transporter activity	1/2046	14/18639	0.0714285714285714	0.650712191034772	0.803767612961025	0.9770206712666
GO:0008392	arachidonate epoxygenase activity	1/2046	14/18639	0.0714285714285714	0.650712191034772	0.803767612961025	0.9770206712666
GO:0043176	amine binding	1/2046	14/18639	0.0714285714285714	0.650712191034772	0.803767612961025	0.9770206712666
GO:0098821	BMP receptor activity	1/2046	14/18639	0.0714285714285714	0.650712191034772	0.803767612961025	0.9770206712666
GO:1901474	azole transmembrane transporter activity	1/2046	14/18639	0.0714285714285714	0.650712191034772	0.803767612961025	0.9770206712666
GO:1901612	cardiolipin binding	1/2046	14/18639	0.0714285714285714	0.650712191034772	0.803767612961025	0.9770206712666
GO:0005044	scavenger receptor activity	2/2046	27/18639	0.0740740740740741	0.674812642554578	0.812721560025511	0.97767160227205
GO:0005385	zinc ion transmembrane transporter activity	2/2046	27/18639	0.0740740740740741	0.674812642554578	0.812721560025511	0.97767160227205
GO:0008395	steroid hydroxylase activity	2/2046	27/18639	0.0740740740740741	0.674812642554578	0.812721560025511	0.97767160227205
GO:0015252	proton channel activity	2/2046	27/18639	0.0740740740740741	0.674812642554578	0.812721560025511	0.97767160227205
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	2/2046	27/18639	0.0740740740740741	0.674812642554578	0.812721560025511	0.97767160227205
GO:0061659	ubiquitin-like protein ligase activity	36/2046	372/18639	0.0967741935483871	0.881610065272916	0.813214712805471	0.97767160227205
GO:0005006	epidermal growth factor receptor activity	4/2046	50/18639	0.08	0.728797653958944	0.813628699435277	0.97767160227205
GO:0005007	fibroblast growth factor receptor activity	4/2046	50/18639	0.08	0.728797653958944	0.813628699435277	0.97767160227205
GO:0005017	platelet-derived growth factor receptor activity	4/2046	50/18639	0.08	0.728797653958944	0.813628699435277	0.97767160227205
GO:0005019	platelet-derived growth factor beta-receptor activity	4/2046	50/18639	0.08	0.728797653958944	0.813628699435277	0.97767160227205
GO:1901981	phosphatidylinositol phosphate binding	17/2046	185/18639	0.0918918918918919	0.837132440358247	0.814566964175688	0.97767160227205
GO:0015297	antiporter activity	12/2046	135/18639	0.0888888888888889	0.809775171065494	0.81923459203738	0.97767160227205
GO:0005254	chloride channel activity	7/2046	83/18639	0.0843373493975904	0.768310779775995	0.819441459079636	0.97767160227205
GO:0004953	icosanoid receptor activity	1/2046	15/18639	0.0666666666666667	0.60733137829912	0.825324201625816	0.97767160227205
GO:0005523	tropomyosin binding	1/2046	15/18639	0.0666666666666667	0.60733137829912	0.825324201625816	0.97767160227205
GO:0015116	sulfate transmembrane transporter activity	1/2046	15/18639	0.0666666666666667	0.60733137829912	0.825324201625816	0.97767160227205
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/2046	15/18639	0.0666666666666667	0.60733137829912	0.825324201625816	0.97767160227205
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/2046	15/18639	0.0666666666666667	0.60733137829912	0.825324201625816	0.97767160227205
GO:0030553	cGMP binding	1/2046	15/18639	0.0666666666666667	0.60733137829912	0.825324201625816	0.97767160227205
GO:0033130	acetylcholine receptor binding	1/2046	15/18639	0.0666666666666667	0.60733137829912	0.825324201625816	0.97767160227205
GO:0047372	monoacylglycerol lipase activity	1/2046	15/18639	0.0666666666666667	0.60733137829912	0.825324201625816	0.97767160227205
GO:0050700	CARD domain binding	1/2046	15/18639	0.0666666666666667	0.60733137829912	0.825324201625816	0.97767160227205
GO:0050780	dopamine receptor binding	1/2046	15/18639	0.0666666666666667	0.60733137829912	0.825324201625816	0.97767160227205
GO:0120283	protein serine/threonine kinase binding	1/2046	15/18639	0.0666666666666667	0.60733137829912	0.825324201625816	0.97767160227205
GO:0140161	monocarboxylate:sodium symporter activity	1/2046	15/18639	0.0666666666666667	0.60733137829912	0.825324201625816	0.97767160227205
GO:0005021	vascular endothelial growth factor receptor activity	4/2046	51/18639	0.0784313725490196	0.714507503881318	0.825677312688055	0.97767160227205
GO:0005030	neurotrophin receptor activity	4/2046	51/18639	0.0784313725490196	0.714507503881318	0.825677312688055	0.97767160227205
GO:0051959	dynein light intermediate chain binding	2/2046	28/18639	0.0714285714285714	0.650712191034772	0.828551474417153	0.980135125388108
GO:0015144	carbohydrate transmembrane transporter activity	3/2046	40/18639	0.075	0.68324780058651	0.830353298233477	0.981326625185018
GO:0016247	channel regulator activity	15/2046	168/18639	0.0892857142857143	0.813390238793465	0.835712536384228	0.982521913687836
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	4/2046	52/18639	0.0769230769230769	0.700766974960523	0.837072628325052	0.982521913687836
GO:0001530	lipopolysaccharide binding	3/2046	41/18639	0.0731707317073171	0.6665832200844	0.842789866488787	0.982521913687836
GO:0001727	lipid kinase activity	3/2046	41/18639	0.0731707317073171	0.6665832200844	0.842789866488787	0.982521913687836
GO:0042169	SH2 domain binding	3/2046	41/18639	0.0731707317073171	0.6665832200844	0.842789866488787	0.982521913687836
GO:0005416	amino acid:monoatomic cation symporter activity	2/2046	29/18639	0.0689655172413793	0.628273839619779	0.843164730552687	0.982521913687836
GO:0051861	glycolipid binding	2/2046	29/18639	0.0689655172413793	0.628273839619779	0.843164730552687	0.982521913687836
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/2046	16/18639	0.0625	0.569373167155425	0.844513778702362	0.982521913687836
GO:0008391	arachidonate monooxygenase activity	1/2046	16/18639	0.0625	0.569373167155425	0.844513778702362	0.982521913687836
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/2046	16/18639	0.0625	0.569373167155425	0.844513778702362	0.982521913687836
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/2046	16/18639	0.0625	0.569373167155425	0.844513778702362	0.982521913687836
GO:0070411	I-SMAD binding	1/2046	16/18639	0.0625	0.569373167155425	0.844513778702362	0.982521913687836
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/2046	16/18639	0.0625	0.569373167155425	0.844513778702362	0.982521913687836
GO:0019003	GDP binding	6/2046	75/18639	0.08	0.728797653958944	0.845186537323113	0.982521913687836
GO:0008509	monoatomic anion transmembrane transporter activity	13/2046	149/18639	0.087248322147651	0.794829656163278	0.845496003362684	0.982521913687836
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	7/2046	86/18639	0.0813953488372093	0.7415092409466	0.846417626299737	0.982521913687836
GO:0070851	growth factor receptor binding	12/2046	139/18639	0.0863309352517986	0.786472288444904	0.847832000566299	0.982521913687836
GO:0038064	collagen receptor activity	4/2046	53/18639	0.0754716981132075	0.687544956565042	0.847837059746985	0.982521913687836
GO:0005543	phospholipid binding	48/2046	497/18639	0.096579476861167	0.879836201962508	0.847954569997524	0.982521913687836
GO:0141108	transporter regulator activity	15/2046	170/18639	0.0882352941176471	0.803820941866483	0.848226678798362	0.982521913687836
GO:0004842	ubiquitin-protein transferase activity	43/2046	449/18639	0.0957683741648107	0.872447080184705	0.850647256099913	0.982521913687836
GO:0003730	mRNA 3'-UTR binding	24/2046	262/18639	0.0916030534351145	0.834501130487341	0.853252366731839	0.982521913687836
GO:0048487	beta-tubulin binding	3/2046	42/18639	0.0714285714285714	0.650712191034772	0.854427984298717	0.982521913687836
GO:0001965	G-protein alpha-subunit binding	2/2046	30/18639	0.0666666666666667	0.60733137829912	0.856637542468508	0.982521913687836
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/2046	30/18639	0.0666666666666667	0.60733137829912	0.856637542468508	0.982521913687836
GO:0031624	ubiquitin conjugating enzyme binding	2/2046	30/18639	0.0666666666666667	0.60733137829912	0.856637542468508	0.982521913687836
GO:0015485	cholesterol binding	4/2046	54/18639	0.0740740740740741	0.674812642554578	0.857993734591014	0.982521913687836
GO:0004550	nucleoside diphosphate kinase activity	1/2046	17/18639	0.0588235294117647	0.535880627910988	0.861596139695487	0.982521913687836
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/2046	17/18639	0.0588235294117647	0.535880627910988	0.861596139695487	0.982521913687836
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/2046	17/18639	0.0588235294117647	0.535880627910988	0.861596139695487	0.982521913687836
GO:0008484	sulfuric ester hydrolase activity	1/2046	17/18639	0.0588235294117647	0.535880627910988	0.861596139695487	0.982521913687836
GO:0016018	cyclosporin A binding	1/2046	17/18639	0.0588235294117647	0.535880627910988	0.861596139695487	0.982521913687836
GO:0017110	nucleoside diphosphate phosphatase activity	1/2046	17/18639	0.0588235294117647	0.535880627910988	0.861596139695487	0.982521913687836
GO:0019198	transmembrane receptor protein phosphatase activity	1/2046	17/18639	0.0588235294117647	0.535880627910988	0.861596139695487	0.982521913687836
GO:0030548	acetylcholine receptor regulator activity	1/2046	17/18639	0.0588235294117647	0.535880627910988	0.861596139695487	0.982521913687836
GO:0045236	CXCR chemokine receptor binding	1/2046	17/18639	0.0588235294117647	0.535880627910988	0.861596139695487	0.982521913687836
GO:0051787	misfolded protein binding	1/2046	17/18639	0.0588235294117647	0.535880627910988	0.861596139695487	0.982521913687836
GO:0070492	oligosaccharide binding	1/2046	17/18639	0.0588235294117647	0.535880627910988	0.861596139695487	0.982521913687836
GO:0008374	O-acyltransferase activity	4/2046	55/18639	0.0727272727272727	0.662543321780858	0.867566266819744	0.987102264448809
GO:0005452	solute:inorganic anion antiporter activity	2/2046	31/18639	0.0645161290322581	0.587740043515278	0.869044060415085	0.987102264448809
GO:1902936	phosphatidylinositol bisphosphate binding	9/2046	111/18639	0.0810810810810811	0.738646270904336	0.872108033575143	0.987102264448809
GO:0016500	protein-hormone receptor activity	5/2046	67/18639	0.0746268656716418	0.679848557797523	0.872267478084544	0.987102264448809
GO:0050840	extracellular matrix binding	5/2046	67/18639	0.0746268656716418	0.679848557797523	0.872267478084544	0.987102264448809
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	10/2046	122/18639	0.0819672131147541	0.74671890774482	0.87394872334526	0.987102264448809
GO:0043014	alpha-tubulin binding	3/2046	44/18639	0.0681818181818182	0.621134364169555	0.875460418530895	0.987102264448809
GO:0004706	JUN kinase kinase kinase activity	1/2046	18/18639	0.0555555555555556	0.506109481915934	0.876802578218902	0.987102264448809
GO:0004970	glutamate-gated receptor activity	1/2046	18/18639	0.0555555555555556	0.506109481915934	0.876802578218902	0.987102264448809
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/2046	18/18639	0.0555555555555556	0.506109481915934	0.876802578218902	0.987102264448809
GO:0017075	syntaxin-1 binding	1/2046	18/18639	0.0555555555555556	0.506109481915934	0.876802578218902	0.987102264448809
GO:0017128	phospholipid scramblase activity	1/2046	18/18639	0.0555555555555556	0.506109481915934	0.876802578218902	0.987102264448809
GO:0050811	GABA receptor binding	1/2046	18/18639	0.0555555555555556	0.506109481915934	0.876802578218902	0.987102264448809
GO:0099602	neurotransmitter receptor regulator activity	1/2046	18/18639	0.0555555555555556	0.506109481915934	0.876802578218902	0.987102264448809
GO:0015370	solute:sodium symporter activity	6/2046	79/18639	0.0759493670886076	0.691896506923048	0.877989426049087	0.987197020958354
GO:0015103	inorganic anion transmembrane transporter activity	14/2046	165/18639	0.0848484848484849	0.772967208744335	0.878485446180754	0.987197020958354
GO:0120015	sterol transfer activity	2/2046	32/18639	0.0625	0.569373167155425	0.88045590560941	0.988511857661474
GO:0004715	non-membrane spanning protein tyrosine kinase activity	3/2046	45/18639	0.0666666666666667	0.60733137829912	0.884930017023124	0.990115045895234
GO:0042605	peptide antigen binding	3/2046	45/18639	0.0666666666666667	0.60733137829912	0.884930017023124	0.990115045895234
GO:0042277	peptide binding	22/2046	249/18639	0.0883534136546185	0.804897007384376	0.88562005192471	0.990115045895234
GO:0140375	immune receptor activity	13/2046	156/18639	0.0833333333333333	0.7591642228739	0.88625406520018	0.990115045895234
GO:0008381	mechanosensitive monoatomic ion channel activity	1/2046	19/18639	0.0526315789473684	0.479472140762463	0.890339011544938	0.990115045895234
GO:0030506	ankyrin binding	1/2046	19/18639	0.0526315789473684	0.479472140762463	0.890339011544938	0.990115045895234
GO:0042834	peptidoglycan binding	1/2046	19/18639	0.0526315789473684	0.479472140762463	0.890339011544938	0.990115045895234
GO:0043395	heparan sulfate proteoglycan binding	1/2046	19/18639	0.0526315789473684	0.479472140762463	0.890339011544938	0.990115045895234
GO:0070003	threonine-type peptidase activity	1/2046	19/18639	0.0526315789473684	0.479472140762463	0.890339011544938	0.990115045895234
GO:0071889	14-3-3 protein binding	2/2046	33/18639	0.0606060606060606	0.552119434817382	0.890941831895416	0.990115045895234
GO:0001216	DNA-binding transcription activator activity	46/2046	491/18639	0.0936863543788187	0.853479940990617	0.892330756330409	0.990115045895234
GO:0004180	carboxypeptidase activity	3/2046	46/18639	0.0652173913043478	0.594128522249139	0.893751204164037	0.990115045895234
GO:0051213	dioxygenase activity	7/2046	93/18639	0.0752688172043011	0.685696717434491	0.896817584155538	0.990115045895234
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	45/2046	484/18639	0.0929752066115702	0.847001405685757	0.900428119111234	0.990115045895234
GO:0070888	E-box binding	4/2046	59/18639	0.0677966101694915	0.617625130473682	0.900493536698075	0.990115045895234
GO:0008175	tRNA methyltransferase activity	2/2046	34/18639	0.0588235294117647	0.535880627910988	0.900567492078811	0.990115045895234
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/2046	34/18639	0.0588235294117647	0.535880627910988	0.900567492078811	0.990115045895234
GO:0051427	hormone receptor binding	2/2046	34/18639	0.0588235294117647	0.535880627910988	0.900567492078811	0.990115045895234
GO:0001614	purinergic nucleotide receptor activity	1/2046	20/18639	0.05	0.45549853372434	0.902388763552406	0.990115045895234
GO:0001972	retinoic acid binding	1/2046	20/18639	0.05	0.45549853372434	0.902388763552406	0.990115045895234
GO:0015464	acetylcholine receptor activity	1/2046	20/18639	0.05	0.45549853372434	0.902388763552406	0.990115045895234
GO:0016408	C-acyltransferase activity	1/2046	20/18639	0.05	0.45549853372434	0.902388763552406	0.990115045895234
GO:0016502	nucleotide receptor activity	1/2046	20/18639	0.05	0.45549853372434	0.902388763552406	0.990115045895234
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/2046	20/18639	0.05	0.45549853372434	0.902388763552406	0.990115045895234
GO:0052745	inositol phosphate phosphatase activity	1/2046	20/18639	0.05	0.45549853372434	0.902388763552406	0.990115045895234
GO:0042562	hormone binding	7/2046	94/18639	0.074468085106383	0.678402071504336	0.902728373828367	0.990115045895234
GO:0140767	enzyme-substrate adaptor activity	11/2046	139/18639	0.079136690647482	0.720932931074495	0.907580173063615	0.994119778970815
GO:0005343	organic acid:sodium symporter activity	2/2046	35/18639	0.0571428571428571	0.520569752827817	0.909395290051178	0.994119778970815
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	1/2046	21/18639	0.0476190476190476	0.433808127356514	0.913115042609916	0.994119778970815
GO:0005123	death receptor binding	1/2046	21/18639	0.0476190476190476	0.433808127356514	0.913115042609916	0.994119778970815
GO:0009975	cyclase activity	1/2046	21/18639	0.0476190476190476	0.433808127356514	0.913115042609916	0.994119778970815
GO:0010314	phosphatidylinositol-5-phosphate binding	1/2046	21/18639	0.0476190476190476	0.433808127356514	0.913115042609916	0.994119778970815
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	23/2046	268/18639	0.0858208955223881	0.781825841467151	0.917252227321965	0.994119778970815
GO:0004190	aspartic-type endopeptidase activity	2/2046	36/18639	0.0555555555555556	0.506109481915934	0.91748430269992	0.994119778970815
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	2/2046	36/18639	0.0555555555555556	0.506109481915934	0.91748430269992	0.994119778970815
GO:0008970	phospholipase A1 activity	1/2046	22/18639	0.0454545454545455	0.414089576113037	0.922663147821008	0.994119778970815
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/2046	22/18639	0.0454545454545455	0.414089576113037	0.922663147821008	0.994119778970815
GO:0016881	acid-amino acid ligase activity	1/2046	22/18639	0.0454545454545455	0.414089576113037	0.922663147821008	0.994119778970815
GO:0031683	G-protein beta/gamma-subunit complex binding	1/2046	22/18639	0.0454545454545455	0.414089576113037	0.922663147821008	0.994119778970815
GO:0033691	sialic acid binding	1/2046	22/18639	0.0454545454545455	0.414089576113037	0.922663147821008	0.994119778970815
GO:0042805	actinin binding	2/2046	37/18639	0.0540540540540541	0.492430847269557	0.924890258077652	0.994119778970815
GO:0070001	aspartic-type peptidase activity	2/2046	37/18639	0.0540540540540541	0.492430847269557	0.924890258077652	0.994119778970815
GO:0061630	ubiquitin protein ligase activity	31/2046	353/18639	0.0878186968838527	0.800025753283544	0.925495928373752	0.994119778970815
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/2046	23/18639	0.0434782608695652	0.396085681499426	0.931162433396462	0.994119778970815
GO:0005158	insulin receptor binding	1/2046	23/18639	0.0434782608695652	0.396085681499426	0.931162433396462	0.994119778970815
GO:0005212	structural constituent of eye lens	1/2046	23/18639	0.0434782608695652	0.396085681499426	0.931162433396462	0.994119778970815
GO:0005283	amino acid:sodium symporter activity	1/2046	23/18639	0.0434782608695652	0.396085681499426	0.931162433396462	0.994119778970815
GO:0016849	phosphorus-oxygen lyase activity	1/2046	23/18639	0.0434782608695652	0.396085681499426	0.931162433396462	0.994119778970815
GO:0031681	G-protein beta-subunit binding	1/2046	23/18639	0.0434782608695652	0.396085681499426	0.931162433396462	0.994119778970815
GO:0042171	lysophosphatidic acid acyltransferase activity	1/2046	23/18639	0.0434782608695652	0.396085681499426	0.931162433396462	0.994119778970815
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/2046	23/18639	0.0434782608695652	0.396085681499426	0.931162433396462	0.994119778970815
GO:0071617	lysophospholipid acyltransferase activity	1/2046	23/18639	0.0434782608695652	0.396085681499426	0.931162433396462	0.994119778970815
GO:0099186	structural constituent of postsynapse	1/2046	23/18639	0.0434782608695652	0.396085681499426	0.931162433396462	0.994119778970815
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/2046	23/18639	0.0434782608695652	0.396085681499426	0.931162433396462	0.994119778970815
GO:0005501	retinoid binding	2/2046	38/18639	0.0526315789473684	0.479472140762463	0.931665558431177	0.994119778970815
GO:0019840	isoprenoid binding	2/2046	38/18639	0.0526315789473684	0.479472140762463	0.931665558431177	0.994119778970815
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/2046	24/18639	0.0416666666666667	0.37958211143695	0.938728057658969	0.994119778970815
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/2046	24/18639	0.0416666666666667	0.37958211143695	0.938728057658969	0.994119778970815
GO:0004806	triacylglycerol lipase activity	1/2046	24/18639	0.0416666666666667	0.37958211143695	0.938728057658969	0.994119778970815
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/2046	24/18639	0.0416666666666667	0.37958211143695	0.938728057658969	0.994119778970815
GO:0030552	cAMP binding	1/2046	24/18639	0.0416666666666667	0.37958211143695	0.938728057658969	0.994119778970815
GO:0035035	histone acetyltransferase binding	1/2046	24/18639	0.0416666666666667	0.37958211143695	0.938728057658969	0.994119778970815
GO:0099094	ligand-gated monoatomic cation channel activity	10/2046	136/18639	0.0735294117647059	0.669850784888736	0.93943537203259	0.994119778970815
GO:0005125	cytokine activity	19/2046	234/18639	0.0811965811965812	0.739698473569441	0.939840537220767	0.994119778970815
GO:0017046	peptide hormone binding	3/2046	53/18639	0.0566037735849057	0.515658717423781	0.940236452136181	0.994119778970815
GO:0071855	neuropeptide receptor binding	2/2046	40/18639	0.05	0.45549853372434	0.943517551159371	0.994119778970815
GO:0001217	DNA-binding transcription repressor activity	23/2046	278/18639	0.0827338129496403	0.753702609759699	0.944068970785758	0.994119778970815
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	4/2046	67/18639	0.0597014925373134	0.543878846238018	0.945415283187833	0.994119778970815
GO:0005537	D-mannose binding	1/2046	25/18639	0.04	0.364398826979472	0.945462540282109	0.994119778970815
GO:0015662	P-type ion transporter activity	1/2046	25/18639	0.04	0.364398826979472	0.945462540282109	0.994119778970815
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/2046	25/18639	0.04	0.364398826979472	0.945462540282109	0.994119778970815
GO:0120020	cholesterol transfer activity	1/2046	25/18639	0.04	0.364398826979472	0.945462540282109	0.994119778970815
GO:0140358	P-type transmembrane transporter activity	1/2046	25/18639	0.04	0.364398826979472	0.945462540282109	0.994119778970815
GO:0042287	MHC protein binding	2/2046	41/18639	0.0487804878048781	0.4443888133896	0.948683073450171	0.994119778970815
GO:0008083	growth factor activity	12/2046	162/18639	0.0740740740740741	0.674812642554578	0.950238517235536	0.994119778970815
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/2046	26/18639	0.0384615384615385	0.350383487480262	0.951457148780165	0.994119778970815
GO:0008066	glutamate receptor activity	1/2046	26/18639	0.0384615384615385	0.350383487480262	0.951457148780165	0.994119778970815
GO:0008157	protein phosphatase 1 binding	1/2046	26/18639	0.0384615384615385	0.350383487480262	0.951457148780165	0.994119778970815
GO:0030247	polysaccharide binding	1/2046	26/18639	0.0384615384615385	0.350383487480262	0.951457148780165	0.994119778970815
GO:0050750	low-density lipoprotein particle receptor binding	1/2046	26/18639	0.0384615384615385	0.350383487480262	0.951457148780165	0.994119778970815
GO:0051139	metal cation:proton antiporter activity	1/2046	26/18639	0.0384615384615385	0.350383487480262	0.951457148780165	0.994119778970815
GO:0070412	R-SMAD binding	1/2046	26/18639	0.0384615384615385	0.350383487480262	0.951457148780165	0.994119778970815
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/2046	56/18639	0.0535714285714286	0.488034143276079	0.95367609966953	0.995595928226432
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	9/2046	130/18639	0.0692307692307692	0.630690277464471	0.955543769865456	0.996703172114728
GO:0005242	inward rectifier potassium channel activity	1/2046	28/18639	0.0357142857142857	0.325356095517386	0.961542824020291	0.999999999220718
GO:0051019	mitogen-activated protein kinase binding	1/2046	28/18639	0.0357142857142857	0.325356095517386	0.961542824020291	0.999999999220718
GO:0051393	alpha-actinin binding	1/2046	28/18639	0.0357142857142857	0.325356095517386	0.961542824020291	0.999999999220718
GO:0015459	potassium channel regulator activity	3/2046	59/18639	0.0508474576271186	0.463218847855261	0.964246637659805	0.999999999220718
GO:0046915	transition metal ion transmembrane transporter activity	2/2046	45/18639	0.0444444444444444	0.404887585532747	0.965175199850001	0.999999999220718
GO:0098918	structural constituent of synapse	1/2046	30/18639	0.0333333333333333	0.30366568914956	0.969533822403885	0.999999999220718
GO:0016411	acylglycerol O-acyltransferase activity	1/2046	31/18639	0.032258064516129	0.293870021757639	0.972883481136845	0.999999999220718
GO:0070325	lipoprotein particle receptor binding	1/2046	31/18639	0.032258064516129	0.293870021757639	0.972883481136845	0.999999999220718
GO:0019239	deaminase activity	1/2046	33/18639	0.0303030303030303	0.276059717408691	0.978518865329274	0.999999999220718
GO:0033218	amide binding	18/2046	247/18639	0.0728744939271255	0.66388450259418	0.980371086545948	0.999999999220718
GO:0015020	glucuronosyltransferase activity	1/2046	34/18639	0.0294117647058824	0.267940313955494	0.980881028155045	0.999999999220718
GO:0015108	chloride transmembrane transporter activity	7/2046	121/18639	0.0578512396694215	0.527023096871137	0.983342836177353	0.999999999220718
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/2046	53/18639	0.0377358490566038	0.343772478282521	0.984226412660368	0.999999999220718
GO:0045505	dynein intermediate chain binding	1/2046	36/18639	0.0277777777777778	0.253054740957967	0.984854956925813	0.999999999220718
GO:0098960	postsynaptic neurotransmitter receptor activity	3/2046	69/18639	0.0434782608695652	0.396085681499426	0.985318099913514	0.999999999220718
GO:0030280	structural constituent of skin epidermis	1/2046	37/18639	0.027027027027027	0.246215423634778	0.986520643004928	0.999999999220718
GO:0016782	transferase activity, transferring sulphur-containing groups	3/2046	70/18639	0.0428571428571429	0.390427314620863	0.986595091420427	0.999999999220718
GO:0015276	ligand-gated monoatomic ion channel activity	12/2046	186/18639	0.0645161290322581	0.587740043515278	0.987284223137642	0.999999999220718
GO:0022834	ligand-gated channel activity	12/2046	188/18639	0.0638297872340425	0.58148748986086	0.988739439583361	0.999999999220718
GO:0005518	collagen binding	3/2046	72/18639	0.0416666666666667	0.37958211143695	0.988836388099334	0.999999999220718
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	3/2046	73/18639	0.0410958904109589	0.374382356485759	0.989817119029746	0.999999999220718
GO:0032451	demethylase activity	1/2046	40/18639	0.025	0.22774926686217	0.990497281764053	0.999999999220718
GO:0008227	G protein-coupled amine receptor activity	1/2046	41/18639	0.024390243902439	0.2221944066948	0.9915426369719	0.999999999220718
GO:0140828	metal cation:monoatomic cation antiporter activity	1/2046	41/18639	0.024390243902439	0.2221944066948	0.9915426369719	0.999999999220718
GO:0030547	signaling receptor inhibitor activity	1/2046	44/18639	0.0227272727272727	0.207044788056518	0.994038177862167	0.999999999220718
GO:0022824	transmitter-gated monoatomic ion channel activity	2/2046	63/18639	0.0317460317460317	0.289205418237676	0.994280307397534	0.999999999220718
GO:0022835	transmitter-gated channel activity	2/2046	63/18639	0.0317460317460317	0.289205418237676	0.994280307397534	0.999999999220718
GO:0008188	neuropeptide receptor activity	1/2046	48/18639	0.0208333333333333	0.189791055718475	0.996260065629747	0.999999999220718
GO:0038187	pattern recognition receptor activity	1/2046	48/18639	0.0208333333333333	0.189791055718475	0.996260065629747	0.999999999220718
GO:0008146	sulfotransferase activity	1/2046	53/18639	0.0188679245283019	0.17188623914126	0.997912362011339	0.999999999220718
GO:0008528	G protein-coupled peptide receptor activity	5/2046	122/18639	0.040983606557377	0.37335945387241	0.998172680196293	0.999999999220718
GO:0001653	peptide receptor activity	5/2046	128/18639	0.0390625	0.355858229472141	0.998915119960428	0.999999999220718
GO:0030594	neurotransmitter receptor activity	3/2046	97/18639	0.0309278350515464	0.281751670344953	0.998963172452001	0.999999999220718
GO:0005262	calcium channel activity	5/2046	131/18639	0.0381679389312977	0.347708804369725	0.999166573262468	0.999999999220718
GO:0001540	amyloid-beta binding	2/2046	83/18639	0.0240963855421687	0.219517365650284	0.99928978364377	0.999999999220718
GO:0015081	sodium ion transmembrane transporter activity	7/2046	164/18639	0.0426829268292683	0.3888402117159	0.999390677591248	0.999999999220718
GO:0015085	calcium ion transmembrane transporter activity	5/2046	147/18639	0.0340136054421769	0.309862948111796	0.999801830086958	0.999999999220718
GO:0030527	structural constituent of chromatin	2/2046	98/18639	0.0204081632653061	0.185917768867078	0.999856580364118	0.999999999220718
GO:0005267	potassium channel activity	3/2046	124/18639	0.0241935483870968	0.220402516318229	0.999930264142561	0.999999999220718
GO:0015079	potassium ion transmembrane transporter activity	4/2046	160/18639	0.025	0.22774926686217	0.999988461019942	0.999999999220718
GO:0005249	voltage-gated potassium channel activity	1/2046	98/18639	0.0102040816326531	0.0929588844335388	0.999989097664958	0.999999999220718
GO:0022836	gated channel activity	14/2046	318/18639	0.0440251572327044	0.401067891329608	0.999992589930098	0.999999999220718
GO:0005244	voltage-gated monoatomic ion channel activity	4/2046	173/18639	0.023121387283237	0.210635160103741	0.999996855335972	0.999999999220718
GO:0022832	voltage-gated channel activity	4/2046	175/18639	0.0228571428571429	0.208227901131127	0.999997429302806	0.999999999220718
GO:0005216	monoatomic ion channel activity	22/2046	448/18639	0.0491071428571429	0.447364631336406	0.999998544543137	0.999999999220718
GO:0005261	monoatomic cation channel activity	14/2046	341/18639	0.0410557184750733	0.374016391327904	0.999998793012189	0.999999999220718
GO:0045182	translation regulator activity	15/2046	356/18639	0.0421348314606742	0.383847078981186	0.999998866727159	0.999999999220718
GO:0022843	voltage-gated monoatomic cation channel activity	2/2046	143/18639	0.013986013986014	0.12741217726555	0.999998944865815	0.999999999220718
GO:0003823	antigen binding	3/2046	174/18639	0.0172413793103448	0.157068459904945	0.999999621108955	0.999999999220718
GO:0046873	metal ion transmembrane transporter activity	20/2046	450/18639	0.0444444444444444	0.404887585532747	0.9999998284581	0.999999999220718
GO:0030371	translation repressor activity	8/2046	329/18639	0.0243161094224924	0.221519043756518	0.999999999220718	0.999999999220718