ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	97/1678	175/18639	0.554285714285714	6.15693172143708	2.98844183422514e-55	3.52934980621989e-52
GO:0045296	cadherin binding	72/1678	334/18639	0.215568862275449	2.39451014538266	1.76690475615492e-12	1.04335725850948e-09
GO:0005201	extracellular matrix structural constituent	42/1678	168/18639	0.25	2.77696662693683	7.0026821704596e-10	2.75672254777093e-07
GO:0048027	mRNA 5'-UTR binding	14/1678	24/18639	0.583333333333333	6.47958879618594	1.79774280863935e-09	4.73930552936253e-07
GO:0016853	isomerase activity	43/1678	180/18639	0.238888888888889	2.65354588796186	2.00647990235501e-09	4.73930552936253e-07
GO:0043021	ribonucleoprotein complex binding	42/1678	177/18639	0.23728813559322	2.63576493404174	3.82141935829207e-09	7.14676363409445e-07
GO:0019843	rRNA binding	23/1678	65/18639	0.353846153846154	3.9304758412029	4.23601570183414e-09	7.14676363409445e-07
GO:0003743	translation initiation factor activity	19/1678	51/18639	0.372549019607843	4.13822477739606	3.57167183892544e-08	5.27268055221367e-06
GO:0003697	single-stranded DNA binding	31/1678	121/18639	0.256198347107438	2.84581703917493	6.33770131594964e-08	7.48482525413652e-06
GO:0051082	unfolded protein binding	31/1678	121/18639	0.256198347107438	2.84581703917493	6.33770131594964e-08	7.48482525413652e-06
GO:0031720	haptoglobin binding	8/1678	10/18639	0.8	8.88629320619786	1.61987851653291e-07	1.73916048002306e-05
GO:0180051	translation factor activity	24/1678	84/18639	0.285714285714286	3.17367614507066	2.15002091663441e-07	2.1159789187877e-05
GO:0016860	intramolecular oxidoreductase activity	18/1678	53/18639	0.339622641509434	3.77248296489532	4.14139928909576e-07	3.76230196955545e-05
GO:0048407	platelet-derived growth factor binding	8/1678	11/18639	0.727272727272727	8.07844836927078	5.46730045263743e-07	4.30458788970987e-05
GO:1990948	ubiquitin ligase inhibitor activity	8/1678	11/18639	0.727272727272727	8.07844836927078	5.46730045263743e-07	4.30458788970987e-05
GO:0030020	extracellular matrix structural constituent conferring tensile strength	16/1678	44/18639	0.363636363636364	4.03922418463539	6.294804300851e-07	4.64635242456565e-05
GO:0008135	translation factor activity, RNA binding	23/1678	83/18639	0.27710843373494	3.07808349009865	6.9733549275237e-07	4.84443068788558e-05
GO:0019838	growth factor binding	31/1678	136/18639	0.227941176470588	2.53194015985417	1.03598854207933e-06	6.50768747870653e-05
GO:0016887	ATP hydrolysis activity	68/1678	417/18639	0.163069544364508	1.81135473028014	1.04696072900444e-06	6.50768747870653e-05
GO:0004601	peroxidase activity	18/1678	57/18639	0.315789473684211	3.507747318236	1.40215028252581e-06	8.27969741831491e-05
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	18/1678	59/18639	0.305084745762712	3.38884062948223	2.45694038729267e-06	0.000138173647494888
GO:0043022	ribosome binding	26/1678	112/18639	0.232142857142857	2.57861186786991	5.25841735113511e-06	0.000273743748167777
GO:0140662	ATP-dependent protein folding chaperone	14/1678	40/18639	0.35	3.88775327771156	5.33541776623702e-06	0.000273743748167777
GO:0003678	DNA helicase activity	20/1678	74/18639	0.27027027027027	3.00212608317495	5.56295508554332e-06	0.000273743748167777
GO:0044183	protein folding chaperone	20/1678	75/18639	0.266666666666667	2.96209773539928	6.94990757724839e-06	0.000328313633949214
GO:0005344	oxygen carrier activity	8/1678	14/18639	0.571428571428571	6.34735229014133	7.76504455507346e-06	0.000352712216136221
GO:0017116	single-stranded DNA helicase activity	17/1678	58/18639	0.293103448275862	3.2557539764087	8.50608349219622e-06	0.000372062392751249
GO:0003756	protein disulfide isomerase activity	9/1678	19/18639	0.473684210526316	5.26162097735399	1.52335344565545e-05	0.000603182106720156
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	9/1678	19/18639	0.473684210526316	5.26162097735399	1.52335344565545e-05	0.000603182106720156
GO:0055105	ubiquitin-protein transferase inhibitor activity	8/1678	15/18639	0.533333333333333	5.92419547079857	1.53221534306559e-05	0.000603182106720156
GO:0015035	protein-disulfide reductase activity	12/1678	34/18639	0.352941176470588	3.92042347332258	2.27714838381035e-05	0.000867520077832267
GO:0004857	enzyme inhibitor activity	63/1678	416/18639	0.151442307692308	1.68220093747135	2.85312294261742e-05	0.00105298068600974
GO:0140104	molecular carrier activity	42/1678	249/18639	0.168674698795181	1.87361603745135	5.24014462607376e-05	0.00187533660708882
GO:0008017	microtubule binding	45/1678	276/18639	0.16304347826087	1.81106519148054	6.70632569461204e-05	0.00232946195451083
GO:0140097	catalytic activity, acting on DNA	52/1678	336/18639	0.154761904761905	1.71907457857994	7.83290902311788e-05	0.00264304730180063
GO:0019825	oxygen binding	11/1678	34/18639	0.323529411764706	3.59372151721237	0.000123830320939733	0.00397583119638191
GO:0008094	ATP-dependent activity, acting on DNA	36/1678	210/18639	0.171428571428571	1.9042056870424	0.000124560333840923	0.00397583119638191
GO:0015036	disulfide oxidoreductase activity	12/1678	40/18639	0.3	3.3323599523242	0.000139381988798718	0.00433184549398122
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	6/1678	11/18639	0.545454545454545	6.05883627695308	0.00016373909913037	0.00495835579674273
GO:0005518	collagen binding	17/1678	72/18639	0.236111111111111	2.62269070321812	0.000173525545233337	0.00512334172301428
GO:0016209	antioxidant activity	19/1678	86/18639	0.22093023255814	2.45406353078138	0.000189174768950941	0.00534395065680968
GO:0008187	poly-pyrimidine tract binding	10/1678	30/18639	0.333333333333333	3.70262216924911	0.000190047356127017	0.00534395065680968
GO:0055106	ubiquitin-protein transferase regulator activity	11/1678	36/18639	0.305555555555556	3.39407032181168	0.000219744854483008	0.00561331819685943
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	11/1678	36/18639	0.305555555555556	3.39407032181168	0.000219744854483008	0.00561331819685943
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	11/1678	36/18639	0.305555555555556	3.39407032181168	0.000219744854483008	0.00561331819685943
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	11/1678	36/18639	0.305555555555556	3.39407032181168	0.000219744854483008	0.00561331819685943
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	14/1678	54/18639	0.259259259259259	2.8798172427493	0.000224484032471801	0.00561331819685943
GO:0015631	tubulin binding	56/1678	385/18639	0.145454545454545	1.61568967385416	0.000228567462145561	0.00561331819685943
GO:0016859	cis-trans isomerase activity	12/1678	42/18639	0.285714285714286	3.17367614507066	0.000232898045424312	0.00561331819685943
GO:0003688	DNA replication origin binding	7/1678	16/18639	0.4375	4.85969159713945	0.000260871529726146	0.00616178553213156
GO:0030515	snoRNA binding	10/1678	32/18639	0.3125	3.47120828367104	0.000345325089843288	0.00799664570793966
GO:0070034	telomerase RNA binding	8/1678	22/18639	0.363636363636364	4.03922418463539	0.000428655983195466	0.00955174936139331
GO:0140517	protein-RNA adaptor activity	8/1678	22/18639	0.363636363636364	4.03922418463539	0.000428655983195466	0.00955174936139331
GO:0000217	DNA secondary structure binding	11/1678	39/18639	0.282051282051282	3.13298798936463	0.000476443088200017	0.0102305324938949
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	11/1678	39/18639	0.282051282051282	3.13298798936463	0.000476443088200017	0.0102305324938949
GO:0005539	glycosaminoglycan binding	38/1678	242/18639	0.15702479338843	1.74421044336528	0.000510426028641089	0.0106800417278304
GO:0031994	insulin-like growth factor I binding	6/1678	13/18639	0.461538461538462	5.1267076189603	0.000519049383448207	0.0106800417278304
GO:0005178	integrin binding	28/1678	161/18639	0.173913043478261	1.93180287091258	0.000528803643269324	0.0106800417278304
GO:0031625	ubiquitin protein ligase binding	45/1678	302/18639	0.149006622516556	1.6551456716842	0.000536170548488968	0.0106800417278304
GO:0003779	actin binding	61/1678	443/18639	0.137697516930023	1.52952563650697	0.000542593144512974	0.0106800417278304
GO:0017134	fibroblast growth factor binding	8/1678	23/18639	0.347826086956522	3.86360574182515	0.000605737909796008	0.0117274831388375
GO:0044389	ubiquitin-like protein ligase binding	47/1678	322/18639	0.145962732919255	1.62133455237306	0.00064845601863783	0.0123520412582464
GO:0003684	damaged DNA binding	16/1678	74/18639	0.216216216216216	2.40170086653996	0.00076092349855282	0.0140452218104295
GO:0042393	histone binding	38/1678	247/18639	0.153846153846154	1.70890253965343	0.00076112971707662	0.0140452218104295
GO:0051087	protein-folding chaperone binding	24/1678	134/18639	0.17910447761194	1.98946862825325	0.000835108756348897	0.0151732837115084
GO:0003727	single-stranded RNA binding	18/1678	89/18639	0.202247191011236	2.24653479931968	0.000851180507192183	0.0152309724089995
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	12/1678	48/18639	0.25	2.77696662693683	0.000884141631193186	0.0154454873299713
GO:0005520	insulin-like growth factor binding	7/1678	19/18639	0.368421052631579	4.09237187127533	0.000902403578127026	0.0154454873299713
GO:0008301	DNA binding, bending	7/1678	19/18639	0.368421052631579	4.09237187127533	0.000902403578127026	0.0154454873299713
GO:0016829	lyase activity	32/1678	200/18639	0.16	1.77725864123957	0.000985968929278314	0.016634704363967
GO:0005522	profilin binding	5/1678	10/18639	0.5	5.55393325387366	0.00100654488146245	0.0167426690846078
GO:0004386	helicase activity	26/1678	155/18639	0.167741935483871	1.863255027106	0.00141575452895227	0.0232223069262866
GO:0005536	D-glucose binding	5/1678	11/18639	0.454545454545455	5.04903023079423	0.00170888303340586	0.0276464501705797
GO:0070182	DNA polymerase binding	7/1678	21/18639	0.333333333333333	3.70262216924911	0.00177382255228405	0.0283092491114523
GO:0019842	vitamin binding	25/1678	150/18639	0.166666666666667	1.85131108462455	0.00189546651421676	0.0298472793771999
GO:0008266	poly(U) RNA binding	8/1678	27/18639	0.296296296296296	3.29121970599921	0.00198069392952866	0.0303792146853682
GO:0008320	protein transmembrane transporter activity	8/1678	27/18639	0.296296296296296	3.29121970599921	0.00198069392952866	0.0303792146853682
GO:0048029	monosaccharide binding	15/1678	74/18639	0.202702702702703	2.25159456238121	0.00217727354444304	0.0329661545639388
GO:0061749	forked DNA-dependent helicase activity	11/1678	47/18639	0.234042553191489	2.59971343798342	0.00253641428650744	0.0372815636925834
GO:0019887	protein kinase regulator activity	37/1678	255/18639	0.145098039215686	1.61172965014373	0.0025560615474999	0.0372815636925834
GO:0046625	sphingolipid binding	8/1678	28/18639	0.285714285714286	3.17367614507066	0.00255699124394518	0.0372815636925834
GO:0140318	protein transporter activity	10/1678	41/18639	0.24390243902439	2.70923573359691	0.00284286736901443	0.040944223936659
GO:0009378	four-way junction helicase activity	11/1678	48/18639	0.229166666666667	2.54555274135876	0.00302763048133059	0.0425670428387075
GO:0036121	double-stranded DNA helicase activity	11/1678	48/18639	0.229166666666667	2.54555274135876	0.00302763048133059	0.0425670428387075
GO:0043236	laminin binding	8/1678	29/18639	0.275862068965517	3.06423903661995	0.00325643800865639	0.0452453328026258
GO:0019208	phosphatase regulator activity	20/1678	117/18639	0.170940170940171	1.89878059961493	0.00381489214712507	0.05238822820645
GO:0051015	actin filament binding	31/1678	209/18639	0.148325358851675	1.64757828583812	0.00390860177197292	0.0530581458931037
GO:0001968	fibronectin binding	8/1678	30/18639	0.266666666666667	2.96209773539928	0.00409569895739369	0.0549661416895676
GO:0003689	DNA clamp loader activity	25/1678	160/18639	0.15625	1.73560414183552	0.00458146418820744	0.0607944854637414
GO:0000287	magnesium ion binding	33/1678	230/18639	0.143478260869565	1.59373736850288	0.00501872211121227	0.0655810635036584
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	21/1678	128/18639	0.1640625	1.82238434892729	0.0050532402869034	0.0655810635036584
GO:0008574	plus-end-directed microtubule motor activity	6/1678	19/18639	0.315789473684211	3.507747318236	0.00512106185146711	0.0657388483324201
GO:1901681	sulfur compound binding	38/1678	275/18639	0.138181818181818	1.53490519016145	0.00522788922030589	0.0663885717116264
GO:0019211	phosphatase activator activity	7/1678	25/18639	0.28	3.11020262216925	0.00532907277424852	0.0669535632594415
GO:0043531	ADP binding	9/1678	38/18639	0.236842105263158	2.630810488677	0.00561069604693859	0.069749810857205
GO:0050840	extracellular matrix binding	13/1678	67/18639	0.194029850746269	2.15525768060769	0.00615978993010717	0.0757782490360059
GO:0022884	macromolecule transmembrane transporter activity	8/1678	32/18639	0.25	2.77696662693683	0.00626371764622158	0.0762623767029659
GO:0016776	phosphotransferase activity, phosphate group as acceptor	9/1678	39/18639	0.230769230769231	2.56335380948015	0.00672326974566471	0.080722036613448
GO:0043024	ribosomal small subunit binding	6/1678	20/18639	0.3	3.3323599523242	0.00676670755692748	0.080722036613448
GO:0003777	microtubule motor activity	13/1678	68/18639	0.191176470588235	2.1235627147164	0.00700343294164807	0.0827105430408637
GO:0009055	electron transfer activity	19/1678	116/18639	0.163793103448276	1.8193919279931	0.00754991893084182	0.0882817253200415
GO:0050997	quaternary ammonium group binding	9/1678	40/18639	0.225	2.49926996424315	0.00799736344395144	0.0918617229453269
GO:1990518	single-stranded 3'-5' DNA helicase activity	10/1678	47/18639	0.212765957446809	2.3633758527122	0.00801164899523173	0.0918617229453269
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	5/1678	15/18639	0.333333333333333	3.70262216924911	0.00818562545006877	0.0920687967288687
GO:0050780	dopamine receptor binding	5/1678	15/18639	0.333333333333333	3.70262216924911	0.00818562545006877	0.0920687967288687
GO:0072542	protein phosphatase activator activity	6/1678	21/18639	0.285714285714286	3.17367614507066	0.00876386155878484	0.0955902404789265
GO:0001094	TFIID-class transcription factor complex binding	4/1678	10/18639	0.4	4.44314660309893	0.00882246927366892	0.0955902404789265
GO:0005528	FK506 binding	4/1678	10/18639	0.4	4.44314660309893	0.00882246927366892	0.0955902404789265
GO:0047429	nucleoside triphosphate diphosphatase activity	4/1678	10/18639	0.4	4.44314660309893	0.00882246927366892	0.0955902404789265
GO:0097110	scaffold protein binding	13/1678	70/18639	0.185714285714286	2.06288949429593	0.00896370225829597	0.0962375669731594
GO:0043138	3'-5' DNA helicase activity	10/1678	48/18639	0.208333333333333	2.31413885578069	0.0093232328146794	0.099195837424652
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	9/1678	41/18639	0.219512195121951	2.43831216023722	0.00944706546502748	0.099615931376763
GO:0003774	cytoskeletal motor activity	23/1678	153/18639	0.150326797385621	1.66980999789666	0.0100795072744951	0.105344230895387
GO:0140597	protein carrier chaperone	27/1678	188/18639	0.143617021276596	1.59527870058073	0.01028474726954	0.105503262255434
GO:0097718	disordered domain specific binding	7/1678	28/18639	0.25	2.77696662693683	0.0103471789986072	0.105503262255434
GO:0019207	kinase regulator activity	38/1678	287/18639	0.132404181184669	1.47072796966689	0.0103627251664948	0.105503262255434
GO:0008142	oxysterol binding	5/1678	16/18639	0.3125	3.47120828367104	0.0110372637094632	0.110466173227763
GO:0070411	I-SMAD binding	5/1678	16/18639	0.3125	3.47120828367104	0.0110372637094632	0.110466173227763
GO:0008201	heparin binding	25/1678	172/18639	0.145348837209302	1.61451548077723	0.0114099222200618	0.113236286906664
GO:0140713	histone chaperone activity	24/1678	164/18639	0.146341463414634	1.62554144015814	0.0119982344284336	0.118082623833168
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	19/1678	122/18639	0.155737704918033	1.72991363645245	0.0127783386517126	0.120793576966467
GO:0004523	RNA-DNA hybrid ribonuclease activity	4/1678	11/18639	0.363636363636364	4.03922418463539	0.0128873756966764	0.120793576966467
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	4/1678	11/18639	0.363636363636364	4.03922418463539	0.0128873756966764	0.120793576966467
GO:0034511	U3 snoRNA binding	4/1678	11/18639	0.363636363636364	4.03922418463539	0.0128873756966764	0.120793576966467
GO:0050786	RAGE receptor binding	4/1678	11/18639	0.363636363636364	4.03922418463539	0.0128873756966764	0.120793576966467
GO:0070990	snRNP binding	4/1678	11/18639	0.363636363636364	4.03922418463539	0.0128873756966764	0.120793576966467
GO:0004602	glutathione peroxidase activity	6/1678	23/18639	0.260869565217391	2.89770430636887	0.0139600090530424	0.1287367986311
GO:0019210	kinase inhibitor activity	15/1678	90/18639	0.166666666666667	1.85131108462455	0.0141139161322065	0.1287367986311
GO:0031491	nucleosome binding	13/1678	74/18639	0.175675675675676	1.95138195406372	0.0141528919143434	0.1287367986311
GO:0005048	signal sequence binding	10/1678	51/18639	0.196078431372549	2.17801304073477	0.0142501047066518	0.1287367986311
GO:0004550	nucleoside diphosphate kinase activity	5/1678	17/18639	0.294117647058824	3.26701956110215	0.0144978782539681	0.1287367986311
GO:0016018	cyclosporin A binding	5/1678	17/18639	0.294117647058824	3.26701956110215	0.0144978782539681	0.1287367986311
GO:0051787	misfolded protein binding	5/1678	17/18639	0.294117647058824	3.26701956110215	0.0144978782539681	0.1287367986311
GO:0019888	protein phosphatase regulator activity	17/1678	107/18639	0.158878504672897	1.76480122085705	0.0148333882375831	0.130733070959594
GO:0036002	pre-mRNA binding	11/1678	59/18639	0.186440677966102	2.07095816246136	0.0150927491430967	0.132033605466646
GO:0003725	double-stranded RNA binding	13/1678	75/18639	0.173333333333333	1.92536352800954	0.0157522111602133	0.136789421913322
GO:0004714	transmembrane receptor protein tyrosine kinase activity	11/1678	60/18639	0.183333333333333	2.03644219308701	0.0170225477496426	0.145333960399047
GO:0005540	hyaluronic acid binding	6/1678	24/18639	0.25	2.77696662693683	0.0172284119016652	0.145333960399047
GO:0050699	WW domain binding	6/1678	24/18639	0.25	2.77696662693683	0.0172284119016652	0.145333960399047
GO:0060229	lipase activator activity	6/1678	24/18639	0.25	2.77696662693683	0.0172284119016652	0.145333960399047
GO:0004860	protein kinase inhibitor activity	14/1678	84/18639	0.166666666666667	1.85131108462455	0.0173558275176998	0.145370441832649
GO:0005527	macrolide binding	4/1678	12/18639	0.333333333333333	3.70262216924911	0.0179743459729564	0.146630530053564
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	4/1678	12/18639	0.333333333333333	3.70262216924911	0.0179743459729564	0.146630530053564
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/1678	12/18639	0.333333333333333	3.70262216924911	0.0179743459729564	0.146630530053564
GO:0042162	telomeric DNA binding	8/1678	38/18639	0.210526315789474	2.33849821215733	0.0180029016577196	0.146630530053564
GO:0000400	four-way junction DNA binding	5/1678	18/18639	0.277777777777778	3.08551847437425	0.018616733745619	0.149567092201198
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	5/1678	18/18639	0.277777777777778	3.08551847437425	0.018616733745619	0.149567092201198
GO:0044325	transmembrane transporter binding	20/1678	136/18639	0.147058823529412	1.63350978055108	0.0195438261857033	0.155954450846727
GO:0003925	G protein activity	10/1678	54/18639	0.185185185185185	2.0570123162495	0.0209002230949216	0.165658815269144
GO:0019199	transmembrane receptor protein kinase activity	13/1678	78/18639	0.166666666666667	1.85131108462455	0.0213793089886927	0.166765933719162
GO:0070717	poly-purine tract binding	7/1678	32/18639	0.21875	2.42984579856973	0.0214635240688507	0.166765933719162
GO:0140142	nucleocytoplasmic carrier activity	7/1678	32/18639	0.21875	2.42984579856973	0.0214635240688507	0.166765933719162
GO:0005200	structural constituent of cytoskeleton	17/1678	112/18639	0.151785714285714	1.68601545206879	0.0224997957369041	0.173674893890744
GO:0046624	sphingolipid transporter activity	5/1678	19/18639	0.263157894736842	2.92312276519666	0.023436616564959	0.177171199307176
GO:0097001	ceramide binding	5/1678	19/18639	0.263157894736842	2.92312276519666	0.023436616564959	0.177171199307176
GO:0016835	carbon-oxygen lyase activity	13/1678	79/18639	0.164556962025316	1.82787676709766	0.0235528181974823	0.177171199307176
GO:0046332	SMAD binding	13/1678	79/18639	0.164556962025316	1.82787676709766	0.0235528181974823	0.177171199307176
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	4/1678	13/18639	0.307692307692308	3.41780507930687	0.0241474214078108	0.178238154266404
GO:0019104	DNA N-glycosylase activity	4/1678	13/18639	0.307692307692308	3.41780507930687	0.0241474214078108	0.178238154266404
GO:0140666	annealing activity	4/1678	13/18639	0.307692307692308	3.41780507930687	0.0241474214078108	0.178238154266404
GO:0008143	poly(A) binding	6/1678	26/18639	0.230769230769231	2.56335380948015	0.0252612884499667	0.185301749437334
GO:0031072	heat shock protein binding	19/1678	131/18639	0.145038167938931	1.61106460799389	0.0255564039782709	0.186309340113197
GO:0140658	ATP-dependent chromatin remodeler activity	22/1678	158/18639	0.139240506329114	1.54666495677494	0.0263456788040409	0.190366938275075
GO:0030170	pyridoxal phosphate binding	10/1678	56/18639	0.178571428571429	1.98354759066916	0.0264353750017886	0.190366938275075
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	19/1678	132/18639	0.143939393939394	1.59885957308484	0.0274248534325115	0.196295466083613
GO:0001618	virus receptor activity	13/1678	81/18639	0.160493827160494	1.78274400741624	0.0283840551108008	0.201937163167805
GO:0016004	phospholipase activator activity	5/1678	20/18639	0.25	2.77696662693683	0.0289932529009695	0.203815664738363
GO:0030742	GTP-dependent protein binding	5/1678	20/18639	0.25	2.77696662693683	0.0289932529009695	0.203815664738363
GO:0070279	vitamin B6 binding	10/1678	57/18639	0.175438596491228	1.94874851013111	0.0295638931044954	0.206597383174018
GO:0140272	exogenous protein binding	13/1678	82/18639	0.158536585365854	1.76100322683799	0.0310537678237105	0.214587925520182
GO:0019992	diacylglycerol binding	4/1678	14/18639	0.285714285714286	3.17367614507066	0.0314511778344805	0.214587925520182
GO:1990825	sequence-specific mRNA binding	4/1678	14/18639	0.285714285714286	3.17367614507066	0.0314511778344805	0.214587925520182
GO:0008307	structural constituent of muscle	8/1678	42/18639	0.19047619047619	2.11578409671377	0.0316158332265128	0.214587925520182
GO:0031492	nucleosomal DNA binding	8/1678	42/18639	0.19047619047619	2.11578409671377	0.0316158332265128	0.214587925520182
GO:0005006	epidermal growth factor receptor activity	9/1678	50/18639	0.18	1.99941597139452	0.0326898892178881	0.219356586172306
GO:0005007	fibroblast growth factor receptor activity	9/1678	50/18639	0.18	1.99941597139452	0.0326898892178881	0.219356586172306
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	24/1678	181/18639	0.132596685082873	1.47286627727036	0.0352944148952323	0.235273009614996
GO:0016866	intramolecular transferase activity	6/1678	28/18639	0.214285714285714	2.380257108803	0.0354602842603466	0.235273009614996
GO:0004712	protein serine/threonine/tyrosine kinase activity	8/1678	43/18639	0.186046511627907	2.06657981539485	0.0358868602684745	0.236104347804306
GO:0005506	iron ion binding	21/1678	154/18639	0.136363636363636	1.51470906923827	0.0359854213418925	0.236104347804306
GO:0051117	ATPase binding	13/1678	84/18639	0.154761904761905	1.71907457857994	0.0369298607999575	0.24096224091022
GO:0098631	cell adhesion mediator activity	12/1678	76/18639	0.157894736842105	1.753873659118	0.0383610114124745	0.248925024605123
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	11/1678	68/18639	0.161764705882353	1.79686075860618	0.0395927228966676	0.25478561214334
GO:0004129	cytochrome-c oxidase activity	4/1678	15/18639	0.266666666666667	2.96209773539928	0.0399113787015393	0.25478561214334
GO:0016846	carbon-sulfur lyase activity	4/1678	15/18639	0.266666666666667	2.96209773539928	0.0399113787015393	0.25478561214334
GO:0019205	nucleobase-containing compound kinase activity	8/1678	44/18639	0.181818181818182	2.01961209231769	0.0405302279575032	0.257345157085007
GO:0003785	actin monomer binding	6/1678	29/18639	0.206896551724138	2.29817927746496	0.0414229695824251	0.258735084411895
GO:0051861	glycolipid binding	6/1678	29/18639	0.206896551724138	2.29817927746496	0.0414229695824251	0.258735084411895
GO:0106222	lncRNA binding	6/1678	29/18639	0.206896551724138	2.29817927746496	0.0414229695824251	0.258735084411895
GO:0061135	endopeptidase regulator activity	24/1678	184/18639	0.130434782608696	1.44885215318443	0.0416254581187638	0.258735084411895
GO:0030021	extracellular matrix structural constituent conferring compression resistance	5/1678	22/18639	0.227272727272727	2.52451511539712	0.0424223540656287	0.260941667455768
GO:0031683	G-protein beta/gamma-subunit complex binding	5/1678	22/18639	0.227272727272727	2.52451511539712	0.0424223540656287	0.260941667455768
GO:0005003	ephrin receptor activity	9/1678	53/18639	0.169811320754717	1.88624148244766	0.0454956278090123	0.276960497125997
GO:0005005	transmembrane-ephrin receptor activity	9/1678	53/18639	0.169811320754717	1.88624148244766	0.0454956278090123	0.276960497125997
GO:0004713	protein tyrosine kinase activity	19/1678	140/18639	0.135714285714286	1.50749616890856	0.0462550875716637	0.280139786780178
GO:0031210	phosphatidylcholine binding	6/1678	30/18639	0.2	2.22157330154946	0.0479805617272745	0.282350496809293
GO:0035925	mRNA 3'-UTR AU-rich region binding	6/1678	30/18639	0.2	2.22157330154946	0.0479805617272745	0.282350496809293
GO:0140297	DNA-binding transcription factor binding	55/1678	488/18639	0.112704918032787	1.2519111842748	0.0485199881450572	0.282350496809293
GO:0004708	MAP kinase kinase activity	4/1678	16/18639	0.25	2.77696662693683	0.0495360836988981	0.282350496809293
GO:0005159	insulin-like growth factor receptor binding	4/1678	16/18639	0.25	2.77696662693683	0.0495360836988981	0.282350496809293
GO:0005324	long-chain fatty acid transmembrane transporter activity	4/1678	16/18639	0.25	2.77696662693683	0.0495360836988981	0.282350496809293
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/1678	16/18639	0.25	2.77696662693683	0.0495360836988981	0.282350496809293
GO:0017070	U6 snRNA binding	4/1678	16/18639	0.25	2.77696662693683	0.0495360836988981	0.282350496809293
GO:0043023	ribosomal large subunit binding	4/1678	16/18639	0.25	2.77696662693683	0.0495360836988981	0.282350496809293
GO:0008171	O-methyltransferase activity	5/1678	23/18639	0.217391304347826	2.41475358864072	0.0503285610135693	0.282350496809293
GO:0017069	snRNA binding	9/1678	54/18639	0.166666666666667	1.85131108462455	0.0504147087518303	0.282350496809293
GO:0140463	chromatin-protein adaptor activity	9/1678	54/18639	0.166666666666667	1.85131108462455	0.0504147087518303	0.282350496809293
GO:0019001	guanyl nucleotide binding	46/1678	400/18639	0.115	1.27740464839094	0.0505652304663481	0.282350496809293
GO:0032561	guanyl ribonucleotide binding	46/1678	400/18639	0.115	1.27740464839094	0.0505652304663481	0.282350496809293
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	8/1678	46/18639	0.173913043478261	1.93180287091258	0.0509733684325894	0.282350496809293
GO:0000510	H3-H4 histone complex chaperone activity	20/1678	151/18639	0.132450331125828	1.47124059705262	0.051638988896241	0.282350496809293
GO:0140584	chromatin extrusion motor activity	20/1678	151/18639	0.132450331125828	1.47124059705262	0.051638988896241	0.282350496809293
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	20/1678	151/18639	0.132450331125828	1.47124059705262	0.051638988896241	0.282350496809293
GO:0140849	ATP-dependent H2AZ histone chaperone activity	20/1678	151/18639	0.132450331125828	1.47124059705262	0.051638988896241	0.282350496809293
GO:0140299	molecular sensor activity	11/1678	71/18639	0.154929577464789	1.72093706458057	0.0518336229933636	0.282350496809293
GO:0061134	peptidase regulator activity	28/1678	226/18639	0.123893805309735	1.37619585051737	0.0519759870388061	0.282350496809293
GO:0035401	histone H3Y41 kinase activity	16/1678	115/18639	0.139130434782609	1.54544229673006	0.0527219446586488	0.282350496809293
GO:0140801	histone H2AXY142 kinase activity	16/1678	115/18639	0.139130434782609	1.54544229673006	0.0527219446586488	0.282350496809293
GO:0004866	endopeptidase inhibitor activity	21/1678	161/18639	0.130434782608696	1.44885215318443	0.0539180293495042	0.282350496809293
GO:0003680	minor groove of adenine-thymine-rich DNA binding	3/1678	10/18639	0.3	3.3323599523242	0.0540315091269264	0.282350496809293
GO:0016868	intramolecular phosphotransferase activity	3/1678	10/18639	0.3	3.3323599523242	0.0540315091269264	0.282350496809293
GO:0031957	very long-chain fatty acid-CoA ligase activity	3/1678	10/18639	0.3	3.3323599523242	0.0540315091269264	0.282350496809293
GO:0031996	thioesterase binding	3/1678	10/18639	0.3	3.3323599523242	0.0540315091269264	0.282350496809293
GO:0032356	oxidized DNA binding	3/1678	10/18639	0.3	3.3323599523242	0.0540315091269264	0.282350496809293
GO:0051880	G-quadruplex DNA binding	3/1678	10/18639	0.3	3.3323599523242	0.0540315091269264	0.282350496809293
GO:0098505	G-rich strand telomeric DNA binding	3/1678	10/18639	0.3	3.3323599523242	0.0540315091269264	0.282350496809293
GO:0015616	DNA translocase activity	20/1678	152/18639	0.131578947368421	1.46156138259833	0.054646641413214	0.283060015390376
GO:0140674	ATP-dependent histone chaperone activity	20/1678	152/18639	0.131578947368421	1.46156138259833	0.054646641413214	0.283060015390376
GO:0072349	modified amino acid transmembrane transporter activity	6/1678	31/18639	0.193548387096774	2.14990964666077	0.0551426406024842	0.2843819150722
GO:0033218	amide binding	30/1678	247/18639	0.121457489878543	1.34913358393692	0.0565542570766468	0.290393815684869
GO:0061775	cohesin loader activity	20/1678	153/18639	0.130718954248366	1.45200869382318	0.0577756840119904	0.295381310901128
GO:0001091	RNA polymerase II general transcription initiation factor binding	5/1678	24/18639	0.208333333333333	2.31413885578069	0.0590391265693336	0.300539691717168
GO:0003712	transcription coregulator activity	55/1678	495/18639	0.111111111111111	1.2342073897497	0.0600612868945189	0.303125360245837
GO:0005092	GDP-dissociation inhibitor activity	4/1678	17/18639	0.235294117647059	2.61361564888172	0.0603170699896457	0.303125360245837
GO:1990226	histone methyltransferase binding	4/1678	17/18639	0.235294117647059	2.61361564888172	0.0603170699896457	0.303125360245837
GO:0019212	phosphatase inhibitor activity	9/1678	56/18639	0.160714285714286	1.78519283160225	0.0612689591255753	0.305327384965169
GO:0043539	protein serine/threonine kinase activator activity	11/1678	73/18639	0.150684931506849	1.67378810390713	0.0612723033333997	0.305327384965169
GO:0031369	translation initiation factor binding	6/1678	32/18639	0.1875	2.08272497020262	0.0629147444179381	0.312194593099096
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	7/1678	40/18639	0.175	1.94387663885578	0.0637964907063784	0.314210352772394
GO:0022853	active monoatomic ion transmembrane transporter activity	16/1678	118/18639	0.135593220338983	1.50615139088099	0.0638530776167439	0.314210352772394
GO:0005525	GTP binding	43/1678	378/18639	0.113756613756614	1.26359327998184	0.0655802229631251	0.321250129267574
GO:0031490	chromatin DNA binding	17/1678	128/18639	0.1328125	1.47526352056019	0.0672377891395695	0.321250129267574
GO:0008526	phosphatidylinositol transfer activity	3/1678	11/18639	0.272727272727273	3.02941813847654	0.0694605591632701	0.321250129267574
GO:0010854	adenylate cyclase regulator activity	3/1678	11/18639	0.272727272727273	3.02941813847654	0.0694605591632701	0.321250129267574
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	3/1678	11/18639	0.272727272727273	3.02941813847654	0.0694605591632701	0.321250129267574
GO:0050998	nitric-oxide synthase binding	3/1678	11/18639	0.272727272727273	3.02941813847654	0.0694605591632701	0.321250129267574
GO:0005004	GPI-linked ephrin receptor activity	8/1678	49/18639	0.163265306122449	1.81352922575466	0.0696359297988983	0.321250129267574
GO:0005008	hepatocyte growth factor receptor activity	8/1678	49/18639	0.163265306122449	1.81352922575466	0.0696359297988983	0.321250129267574
GO:0005009	insulin receptor activity	8/1678	49/18639	0.163265306122449	1.81352922575466	0.0696359297988983	0.321250129267574
GO:0005011	macrophage colony-stimulating factor receptor activity	8/1678	49/18639	0.163265306122449	1.81352922575466	0.0696359297988983	0.321250129267574
GO:0005018	platelet-derived growth factor alpha-receptor activity	8/1678	49/18639	0.163265306122449	1.81352922575466	0.0696359297988983	0.321250129267574
GO:0005020	stem cell factor receptor activity	8/1678	49/18639	0.163265306122449	1.81352922575466	0.0696359297988983	0.321250129267574
GO:0008288	boss receptor activity	8/1678	49/18639	0.163265306122449	1.81352922575466	0.0696359297988983	0.321250129267574
GO:0036332	placental growth factor receptor activity	8/1678	49/18639	0.163265306122449	1.81352922575466	0.0696359297988983	0.321250129267574
GO:0038062	protein tyrosine kinase collagen receptor activity	8/1678	49/18639	0.163265306122449	1.81352922575466	0.0696359297988983	0.321250129267574
GO:0060175	brain-derived neurotrophic factor receptor activity	8/1678	49/18639	0.163265306122449	1.81352922575466	0.0696359297988983	0.321250129267574
GO:0016877	ligase activity, forming carbon-sulfur bonds	7/1678	41/18639	0.170731707317073	1.89646501351783	0.0712269891707381	0.325592918109483
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	6/1678	33/18639	0.181818181818182	2.01961209231769	0.071298404290409	0.325592918109483
GO:0003746	translation elongation factor activity	4/1678	18/18639	0.222222222222222	2.4684147794994	0.0722314517736534	0.325592918109483
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	4/1678	18/18639	0.222222222222222	2.4684147794994	0.0722314517736534	0.325592918109483
GO:0008525	phosphatidylcholine transporter activity	4/1678	18/18639	0.222222222222222	2.4684147794994	0.0722314517736534	0.325592918109483
GO:1901611	phosphatidylglycerol binding	4/1678	18/18639	0.222222222222222	2.4684147794994	0.0722314517736534	0.325592918109483
GO:0005017	platelet-derived growth factor receptor activity	8/1678	50/18639	0.16	1.77725864123957	0.0766732708619478	0.342996715484699
GO:0005019	platelet-derived growth factor beta-receptor activity	8/1678	50/18639	0.16	1.77725864123957	0.0766732708619478	0.342996715484699
GO:0070006	metalloaminopeptidase activity	5/1678	26/18639	0.192307692307692	2.13612817456679	0.0788597873633877	0.348788168823387
GO:0070412	R-SMAD binding	5/1678	26/18639	0.192307692307692	2.13612817456679	0.0788597873633877	0.348788168823387
GO:0120014	phospholipid transfer activity	5/1678	26/18639	0.192307692307692	2.13612817456679	0.0788597873633877	0.348788168823387
GO:0035198	miRNA binding	7/1678	42/18639	0.166666666666667	1.85131108462455	0.0791492203595831	0.348788168823387
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	6/1678	34/18639	0.176470588235294	1.96021173666129	0.0802912283741414	0.351278702492766
GO:0030414	peptidase inhibitor activity	21/1678	169/18639	0.124260355029586	1.38026743587393	0.0812562658202532	0.351278702492766
GO:0003713	transcription coactivator activity	30/1678	256/18639	0.1171875	1.30170310637664	0.0816477395075738	0.351278702492766
GO:0030145	manganese ion binding	10/1678	68/18639	0.147058823529412	1.63350978055108	0.0822496494892564	0.351278702492766
GO:0032934	sterol binding	10/1678	68/18639	0.147058823529412	1.63350978055108	0.0822496494892564	0.351278702492766
GO:1990841	promoter-specific chromatin binding	10/1678	68/18639	0.147058823529412	1.63350978055108	0.0822496494892564	0.351278702492766
GO:0004867	serine-type endopeptidase inhibitor activity	13/1678	95/18639	0.136842105263158	1.52002383790226	0.0835610491252306	0.351278702492766
GO:0005010	insulin-like growth factor receptor activity	8/1678	51/18639	0.156862745098039	1.74241043258781	0.084121084675677	0.351278702492766
GO:0005021	vascular endothelial growth factor receptor activity	8/1678	51/18639	0.156862745098039	1.74241043258781	0.084121084675677	0.351278702492766
GO:0005030	neurotrophin receptor activity	8/1678	51/18639	0.156862745098039	1.74241043258781	0.084121084675677	0.351278702492766
GO:0016830	carbon-carbon lyase activity	8/1678	51/18639	0.156862745098039	1.74241043258781	0.084121084675677	0.351278702492766
GO:0015245	fatty acid transmembrane transporter activity	4/1678	19/18639	0.210526315789474	2.33849821215733	0.0852434078293052	0.351278702492766
GO:0050145	nucleoside monophosphate kinase activity	4/1678	19/18639	0.210526315789474	2.33849821215733	0.0852434078293052	0.351278702492766
GO:0005049	nuclear export signal receptor activity	3/1678	12/18639	0.25	2.77696662693683	0.086622630226708	0.351278702492766
GO:0005095	GTPase inhibitor activity	3/1678	12/18639	0.25	2.77696662693683	0.086622630226708	0.351278702492766
GO:0016801	hydrolase activity, acting on ether bonds	3/1678	12/18639	0.25	2.77696662693683	0.086622630226708	0.351278702492766
GO:0016803	ether hydrolase activity	3/1678	12/18639	0.25	2.77696662693683	0.086622630226708	0.351278702492766
GO:0016840	carbon-nitrogen lyase activity	3/1678	12/18639	0.25	2.77696662693683	0.086622630226708	0.351278702492766
GO:0017166	vinculin binding	3/1678	12/18639	0.25	2.77696662693683	0.086622630226708	0.351278702492766
GO:0031543	peptidyl-proline dioxygenase activity	3/1678	12/18639	0.25	2.77696662693683	0.086622630226708	0.351278702492766
GO:0043047	single-stranded telomeric DNA binding	3/1678	12/18639	0.25	2.77696662693683	0.086622630226708	0.351278702492766
GO:0045295	gamma-catenin binding	3/1678	12/18639	0.25	2.77696662693683	0.086622630226708	0.351278702492766
GO:0097371	MDM2/MDM4 family protein binding	3/1678	12/18639	0.25	2.77696662693683	0.086622630226708	0.351278702492766
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	9/1678	60/18639	0.15	1.6661799761621	0.0871504316938021	0.351278702492766
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	9/1678	60/18639	0.15	1.6661799761621	0.0871504316938021	0.351278702492766
GO:0140566	histone reader activity	6/1678	35/18639	0.171428571428571	1.9042056870424	0.0898870297755715	0.360090309433168
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	5/1678	27/18639	0.185185185185185	2.0570123162495	0.0899463516365662	0.360090309433168
GO:0030246	carbohydrate binding	32/1678	280/18639	0.114285714285714	1.26947045802826	0.095727660140187	0.381940427789057
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	4/1678	20/18639	0.2	2.22157330154946	0.0993059465613891	0.390711276878087
GO:0031418	L-ascorbic acid binding	4/1678	20/18639	0.2	2.22157330154946	0.0993059465613891	0.390711276878087
GO:0061608	nuclear import signal receptor activity	4/1678	20/18639	0.2	2.22157330154946	0.0993059465613891	0.390711276878087
GO:0140664	ATP-dependent DNA damage sensor activity	4/1678	20/18639	0.2	2.22157330154946	0.0993059465613891	0.390711276878087
GO:0003924	GTPase activity	37/1678	331/18639	0.11178247734139	1.24166483621345	0.0996298383557399	0.390711276878087
GO:0004869	cysteine-type endopeptidase inhibitor activity	6/1678	36/18639	0.166666666666667	1.85131108462455	0.100075992411771	0.390711276878087
GO:0038064	collagen receptor activity	8/1678	53/18639	0.150943396226415	1.67665909550903	0.100241758589382	0.390711276878087
GO:0046875	ephrin receptor binding	5/1678	28/18639	0.178571428571429	1.98354759066916	0.101791148892266	0.395445219874231
GO:0000049	tRNA binding	11/1678	80/18639	0.1375	1.52733164481526	0.10276659607482	0.397925737588075
GO:0003964	RNA-directed DNA polymerase activity	3/1678	13/18639	0.230769230769231	2.56335380948015	0.105365192872377	0.400116697049123
GO:0005542	folic acid binding	3/1678	13/18639	0.230769230769231	2.56335380948015	0.105365192872377	0.400116697049123
GO:0008035	high-density lipoprotein particle binding	3/1678	13/18639	0.230769230769231	2.56335380948015	0.105365192872377	0.400116697049123
GO:0008253	5'-nucleotidase activity	3/1678	13/18639	0.230769230769231	2.56335380948015	0.105365192872377	0.400116697049123
GO:0061459	L-arginine transmembrane transporter activity	3/1678	13/18639	0.230769230769231	2.56335380948015	0.105365192872377	0.400116697049123
GO:0097157	pre-mRNA intronic binding	3/1678	13/18639	0.230769230769231	2.56335380948015	0.105365192872377	0.400116697049123
GO:0015485	cholesterol binding	8/1678	54/18639	0.148148148148148	1.6456098529996	0.108907332474174	0.410384274884466
GO:0051287	NAD binding	8/1678	54/18639	0.148148148148148	1.6456098529996	0.108907332474174	0.410384274884466
GO:0016922	nuclear receptor binding	17/1678	137/18639	0.124087591240876	1.37834839877157	0.10911148375421	0.410384274884466
GO:0015399	primary active transmembrane transporter activity	20/1678	166/18639	0.120481927710843	1.33829716960811	0.110161346006623	0.413017617885149
GO:0043394	proteoglycan binding	6/1678	37/18639	0.162162162162162	1.80127564990497	0.11084486900671	0.414265159167484
GO:0005109	frizzled binding	6/1678	38/18639	0.157894736842105	1.753873659118	0.122177205562988	0.453494101025583
GO:0042887	amide transmembrane transporter activity	6/1678	38/18639	0.157894736842105	1.753873659118	0.122177205562988	0.453494101025583
GO:0052689	carboxylic ester hydrolase activity	12/1678	92/18639	0.130434782608696	1.44885215318443	0.122493326187266	0.453494101025583
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/1678	14/18639	0.214285714285714	2.380257108803	0.125523560609985	0.460382997144076
GO:0044548	S100 protein binding	3/1678	14/18639	0.214285714285714	2.380257108803	0.125523560609985	0.460382997144076
GO:0098847	sequence-specific single stranded DNA binding	3/1678	14/18639	0.214285714285714	2.380257108803	0.125523560609985	0.460382997144076
GO:0016769	transferase activity, transferring nitrogenous groups	5/1678	30/18639	0.166666666666667	1.85131108462455	0.127645311152725	0.465275038491876
GO:0098918	structural constituent of synapse	5/1678	30/18639	0.166666666666667	1.85131108462455	0.127645311152725	0.465275038491876
GO:0016878	acid-thiol ligase activity	5/1678	31/18639	0.161290322580645	1.79159137221731	0.141588132412386	0.512931240426467
GO:0070325	lipoprotein particle receptor binding	5/1678	31/18639	0.161290322580645	1.79159137221731	0.141588132412386	0.512931240426467
GO:0016500	protein-hormone receptor activity	9/1678	67/18639	0.134328358208955	1.49210147118994	0.145781002377084	0.51980490056995
GO:0004177	aminopeptidase activity	6/1678	40/18639	0.15	1.6661799761621	0.146451897966322	0.51980490056995
GO:0004467	long-chain fatty acid-CoA ligase activity	3/1678	15/18639	0.2	2.22157330154946	0.146926606087097	0.51980490056995
GO:0005041	low-density lipoprotein particle receptor activity	3/1678	15/18639	0.2	2.22157330154946	0.146926606087097	0.51980490056995
GO:0008252	nucleotidase activity	3/1678	15/18639	0.2	2.22157330154946	0.146926606087097	0.51980490056995
GO:0033130	acetylcholine receptor binding	3/1678	15/18639	0.2	2.22157330154946	0.146926606087097	0.51980490056995
GO:0048531	beta-1,3-galactosyltransferase activity	3/1678	15/18639	0.2	2.22157330154946	0.146926606087097	0.51980490056995
GO:0099186	structural constituent of postsynapse	4/1678	23/18639	0.173913043478261	1.93180287091258	0.147195877851148	0.51980490056995
GO:0061980	regulatory RNA binding	8/1678	58/18639	0.137931034482759	1.53211951830997	0.147446775352187	0.51980490056995
GO:0016763	pentosyltransferase activity	7/1678	49/18639	0.142857142857143	1.58683807253533	0.147926875557182	0.519945357241165
GO:0019903	protein phosphatase binding	17/1678	144/18639	0.118055555555556	1.31134535160906	0.150692988963083	0.528096201677747
GO:0001221	transcription coregulator binding	14/1678	115/18639	0.121739130434783	1.3522620096388	0.151724007162851	0.528572426133709
GO:0017124	SH3 domain binding	14/1678	115/18639	0.121739130434783	1.3522620096388	0.151724007162851	0.528572426133709
GO:0003714	transcription corepressor activity	23/1678	204/18639	0.112745098039216	1.25235749842249	0.154444511665282	0.536109725919571
GO:0008378	galactosyltransferase activity	5/1678	32/18639	0.15625	1.73560414183552	0.156157278337284	0.536109725919571
GO:0043425	bHLH transcription factor binding	5/1678	32/18639	0.15625	1.73560414183552	0.156157278337284	0.536109725919571
GO:0071813	lipoprotein particle binding	5/1678	32/18639	0.15625	1.73560414183552	0.156157278337284	0.536109725919571
GO:0071814	protein-lipid complex binding	5/1678	32/18639	0.15625	1.73560414183552	0.156157278337284	0.536109725919571
GO:0042169	SH2 domain binding	6/1678	41/18639	0.146341463414634	1.62554144015814	0.159347596616994	0.545476845230927
GO:0002020	protease binding	16/1678	136/18639	0.117647058823529	1.30680782444086	0.162797335911681	0.555675299744783
GO:0050431	transforming growth factor beta binding	4/1678	24/18639	0.166666666666667	1.85131108462455	0.164827228107511	0.559370564353364
GO:0140612	DNA damage sensor activity	4/1678	24/18639	0.166666666666667	1.85131108462455	0.164827228107511	0.559370564353364
GO:0005521	lamin binding	3/1678	16/18639	0.1875	2.08272497020262	0.169401342022835	0.569980014042644
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/1678	16/18639	0.1875	2.08272497020262	0.169401342022835	0.569980014042644
GO:0097027	ubiquitin-protein transferase activator activity	3/1678	16/18639	0.1875	2.08272497020262	0.169401342022835	0.569980014042644
GO:0035173	histone kinase activity	38/1678	360/18639	0.105555555555556	1.17249702026222	0.171110069934889	0.572964116099261
GO:0016874	ligase activity	19/1678	167/18639	0.11377245508982	1.2637692433964	0.171860978571889	0.572964116099261
GO:0031406	carboxylic acid binding	21/1678	187/18639	0.112299465240642	1.24740746878446	0.171974449824767	0.572964116099261
GO:0042056	chemoattractant activity	6/1678	42/18639	0.142857142857143	1.58683807253533	0.172713992659896	0.572964116099261
GO:0051879	Hsp90 protein binding	6/1678	42/18639	0.142857142857143	1.58683807253533	0.172713992659896	0.572964116099261
GO:0008028	monocarboxylic acid transmembrane transporter activity	9/1678	70/18639	0.128571428571429	1.4281542652818	0.175759550402813	0.581434254974012
GO:0008514	organic anion transmembrane transporter activity	29/1678	269/18639	0.107806691449814	1.19750233726644	0.177677882182733	0.586138488429631
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	8/1678	61/18639	0.131147540983607	1.45676937806522	0.18013377486368	0.592584925108653
GO:0008139	nuclear localization sequence binding	4/1678	25/18639	0.16	1.77725864123957	0.183165293703953	0.593113026798158
GO:0008483	transaminase activity	4/1678	25/18639	0.16	1.77725864123957	0.183165293703953	0.593113026798158
GO:0015645	fatty acid ligase activity	4/1678	25/18639	0.16	1.77725864123957	0.183165293703953	0.593113026798158
GO:0042974	nuclear retinoic acid receptor binding	4/1678	25/18639	0.16	1.77725864123957	0.183165293703953	0.593113026798158
GO:0120515	fatty acid-CoA ligase activity	4/1678	25/18639	0.16	1.77725864123957	0.183165293703953	0.593113026798158
GO:0005080	protein kinase C binding	7/1678	52/18639	0.134615384615385	1.49528972219675	0.183896155868674	0.593113026798158
GO:0043177	organic acid binding	21/1678	189/18639	0.111111111111111	1.2342073897497	0.184510552428769	0.593113026798158
GO:0008375	acetylglucosaminyltransferase activity	6/1678	43/18639	0.13953488372093	1.54993486154614	0.186522529966984	0.593113026798158
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6/1678	43/18639	0.13953488372093	1.54993486154614	0.186522529966984	0.593113026798158
GO:0048156	tau protein binding	6/1678	43/18639	0.13953488372093	1.54993486154614	0.186522529966984	0.593113026798158
GO:0016831	carboxy-lyase activity	5/1678	34/18639	0.147058823529412	1.63350978055108	0.187003652207738	0.593113026798158
GO:0030332	cyclin binding	5/1678	34/18639	0.147058823529412	1.63350978055108	0.187003652207738	0.593113026798158
GO:0090482	vitamin transmembrane transporter activity	5/1678	34/18639	0.147058823529412	1.63350978055108	0.187003652207738	0.593113026798158
GO:0043130	ubiquitin binding	12/1678	100/18639	0.12	1.33294398092968	0.187325282807547	0.593113026798158
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/1678	17/18639	0.176470588235294	1.96021173666129	0.192776543172804	0.597556686317799
GO:0008429	phosphatidylethanolamine binding	3/1678	17/18639	0.176470588235294	1.96021173666129	0.192776543172804	0.597556686317799
GO:0017110	nucleoside diphosphate phosphatase activity	3/1678	17/18639	0.176470588235294	1.96021173666129	0.192776543172804	0.597556686317799
GO:0030169	low-density lipoprotein particle binding	3/1678	17/18639	0.176470588235294	1.96021173666129	0.192776543172804	0.597556686317799
GO:0032977	membrane insertase activity	3/1678	17/18639	0.176470588235294	1.96021173666129	0.192776543172804	0.597556686317799
GO:0046965	nuclear retinoid X receptor binding	3/1678	17/18639	0.176470588235294	1.96021173666129	0.192776543172804	0.597556686317799
GO:0070402	NADPH binding	3/1678	17/18639	0.176470588235294	1.96021173666129	0.192776543172804	0.597556686317799
GO:0070492	oligosaccharide binding	3/1678	17/18639	0.176470588235294	1.96021173666129	0.192776543172804	0.597556686317799
GO:0004864	protein phosphatase inhibitor activity	7/1678	53/18639	0.132075471698113	1.4670767085704	0.196626172845957	0.606306814963643
GO:0140296	general transcription initiation factor binding	7/1678	53/18639	0.132075471698113	1.4670767085704	0.196626172845957	0.606306814963643
GO:0008198	ferrous iron binding	4/1678	26/18639	0.153846153846154	1.70890253965343	0.202129931220419	0.617901916909927
GO:0050681	nuclear androgen receptor binding	4/1678	26/18639	0.153846153846154	1.70890253965343	0.202129931220419	0.617901916909927
GO:0050750	low-density lipoprotein particle receptor binding	4/1678	26/18639	0.153846153846154	1.70890253965343	0.202129931220419	0.617901916909927
GO:0005154	epidermal growth factor receptor binding	5/1678	35/18639	0.142857142857143	1.58683807253533	0.203189755946433	0.617901916909927
GO:0016229	steroid dehydrogenase activity	5/1678	35/18639	0.142857142857143	1.58683807253533	0.203189755946433	0.617901916909927
GO:1901682	sulfur compound transmembrane transporter activity	8/1678	63/18639	0.126984126984127	1.41052273114252	0.203525694900899	0.617901916909927
GO:0020037	heme binding	16/1678	142/18639	0.112676056338028	1.25159059242223	0.207674860174243	0.628882076578926
GO:0000900	mRNA regulatory element binding translation repressor activity	3/1678	18/18639	0.166666666666667	1.85131108462455	0.216885561452634	0.635676192096307
GO:0030228	lipoprotein particle receptor activity	3/1678	18/18639	0.166666666666667	1.85131108462455	0.216885561452634	0.635676192096307
GO:0031690	adrenergic receptor binding	3/1678	18/18639	0.166666666666667	1.85131108462455	0.216885561452634	0.635676192096307
GO:0070064	proline-rich region binding	3/1678	18/18639	0.166666666666667	1.85131108462455	0.216885561452634	0.635676192096307
GO:0070628	proteasome binding	3/1678	18/18639	0.166666666666667	1.85131108462455	0.216885561452634	0.635676192096307
GO:0098641	cadherin binding involved in cell-cell adhesion	3/1678	18/18639	0.166666666666667	1.85131108462455	0.216885561452634	0.635676192096307
GO:0004364	glutathione transferase activity	4/1678	27/18639	0.148148148148148	1.6456098529996	0.221640118974133	0.635676192096307
GO:0016405	CoA-ligase activity	4/1678	27/18639	0.148148148148148	1.6456098529996	0.221640118974133	0.635676192096307
GO:0098632	cell-cell adhesion mediator activity	7/1678	55/18639	0.127272727272727	1.41372846462239	0.223066776064405	0.635676192096307
GO:0016757	glycosyltransferase activity	28/1678	267/18639	0.104868913857678	1.16486989594354	0.224008265209169	0.635676192096307
GO:0000182	rDNA binding	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0005337	nucleoside transmembrane transporter activity	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0005345	purine nucleobase transmembrane transporter activity	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0016427	tRNA (cytidine) methyltransferase activity	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0030957	Tat protein binding	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0033204	ribonuclease P RNA binding	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0035256	G protein-coupled glutamate receptor binding	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0035374	chondroitin sulfate binding	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0043208	glycosphingolipid binding	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0097177	mitochondrial ribosome binding	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0140940	histone H2A methyltransferase activity	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:1990259	histone H2AQ104 methyltransferase activity	2/1678	10/18639	0.2	2.22157330154946	0.225527793808935	0.635676192096307
GO:0038024	cargo receptor activity	8/1678	65/18639	0.123076923076923	1.36712203172275	0.228047507697794	0.641247872835939
GO:0022829	wide pore channel activity	5/1678	37/18639	0.135135135135135	1.50106304158748	0.236848529867369	0.664413571908226
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	3/1678	19/18639	0.157894736842105	1.753873659118	0.241568465257008	0.666699188752878
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/1678	19/18639	0.157894736842105	1.753873659118	0.241568465257008	0.666699188752878
GO:0031420	alkali metal ion binding	3/1678	19/18639	0.157894736842105	1.753873659118	0.241568465257008	0.666699188752878
GO:0043395	heparan sulfate proteoglycan binding	3/1678	19/18639	0.157894736842105	1.753873659118	0.241568465257008	0.666699188752878
GO:0140036	ubiquitin-modified protein reader activity	3/1678	19/18639	0.157894736842105	1.753873659118	0.241568465257008	0.666699188752878
GO:0045499	chemorepellent activity	4/1678	28/18639	0.142857142857143	1.58683807253533	0.241614947321111	0.666699188752878
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	4/1678	28/18639	0.142857142857143	1.58683807253533	0.241614947321111	0.666699188752878
GO:0051536	iron-sulfur cluster binding	9/1678	76/18639	0.118421052631579	1.3154052443385	0.243018401475447	0.669008699632874
GO:0050660	flavin adenine dinucleotide binding	10/1678	86/18639	0.116279069767442	1.29161238462178	0.24423094994965	0.67078314393148
GO:0015932	nucleobase-containing compound transmembrane transporter activity	7/1678	57/18639	0.12280701754386	1.36412395709178	0.250658307202008	0.681479876090709
GO:0016504	peptidase activator activity	7/1678	57/18639	0.12280701754386	1.36412395709178	0.250658307202008	0.681479876090709
GO:0005319	lipid transporter activity	19/1678	178/18639	0.106741573033708	1.18567114408539	0.250877706099252	0.681479876090709
GO:0000146	microfilament motor activity	5/1678	38/18639	0.131578947368421	1.46156138259833	0.254222972943791	0.681479876090709
GO:0051540	metal cluster binding	9/1678	77/18639	0.116883116883117	1.29832205934709	0.255020653091099	0.681479876090709
GO:0000099	sulfur amino acid transmembrane transporter activity	2/1678	11/18639	0.181818181818182	2.01961209231769	0.260209401507972	0.681479876090709
GO:0002162	dystroglycan binding	2/1678	11/18639	0.181818181818182	2.01961209231769	0.260209401507972	0.681479876090709
GO:0008046	axon guidance receptor activity	2/1678	11/18639	0.181818181818182	2.01961209231769	0.260209401507972	0.681479876090709
GO:0008199	ferric iron binding	2/1678	11/18639	0.181818181818182	2.01961209231769	0.260209401507972	0.681479876090709
GO:0015205	nucleobase transmembrane transporter activity	2/1678	11/18639	0.181818181818182	2.01961209231769	0.260209401507972	0.681479876090709
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/1678	11/18639	0.181818181818182	2.01961209231769	0.260209401507972	0.681479876090709
GO:0032404	mismatch repair complex binding	2/1678	11/18639	0.181818181818182	2.01961209231769	0.260209401507972	0.681479876090709
GO:0032794	GTPase activating protein binding	2/1678	11/18639	0.181818181818182	2.01961209231769	0.260209401507972	0.681479876090709
GO:0034056	estrogen response element binding	2/1678	11/18639	0.181818181818182	2.01961209231769	0.260209401507972	0.681479876090709
GO:0045294	alpha-catenin binding	2/1678	11/18639	0.181818181818182	2.01961209231769	0.260209401507972	0.681479876090709
GO:0047676	arachidonate-CoA ligase activity	2/1678	11/18639	0.181818181818182	2.01961209231769	0.260209401507972	0.681479876090709
GO:0048185	activin binding	2/1678	11/18639	0.181818181818182	2.01961209231769	0.260209401507972	0.681479876090709
GO:0097493	structural molecule activity conferring elasticity	2/1678	11/18639	0.181818181818182	2.01961209231769	0.260209401507972	0.681479876090709
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/1678	11/18639	0.181818181818182	2.01961209231769	0.260209401507972	0.681479876090709
GO:0180030	inositol phosphate kinase activity	2/1678	11/18639	0.181818181818182	2.01961209231769	0.260209401507972	0.681479876090709
GO:0140996	histone H3 kinase activity	36/1678	357/18639	0.100840336134454	1.12012099237788	0.260334218165106	0.681479876090709
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	4/1678	29/18639	0.137931034482759	1.53211951830997	0.261974482426064	0.681479876090709
GO:0035250	UDP-galactosyltransferase activity	4/1678	29/18639	0.137931034482759	1.53211951830997	0.261974482426064	0.681479876090709
GO:0097472	cyclin-dependent protein kinase activity	4/1678	29/18639	0.137931034482759	1.53211951830997	0.261974482426064	0.681479876090709
GO:0005496	steroid binding	12/1678	108/18639	0.111111111111111	1.2342073897497	0.264857960860672	0.681691645111222
GO:0005548	phospholipid transporter activity	8/1678	68/18639	0.117647058823529	1.30680782444086	0.266634619390244	0.681691645111222
GO:0000339	RNA cap binding	3/1678	20/18639	0.15	1.6661799761621	0.266673615615059	0.681691645111222
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	3/1678	20/18639	0.15	1.6661799761621	0.266673615615059	0.681691645111222
GO:0010851	cyclase regulator activity	3/1678	20/18639	0.15	1.6661799761621	0.266673615615059	0.681691645111222
GO:0015095	magnesium ion transmembrane transporter activity	3/1678	20/18639	0.15	1.6661799761621	0.266673615615059	0.681691645111222
GO:0016408	C-acyltransferase activity	3/1678	20/18639	0.15	1.6661799761621	0.266673615615059	0.681691645111222
GO:0042288	MHC class I protein binding	3/1678	20/18639	0.15	1.6661799761621	0.266673615615059	0.681691645111222
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	5/1678	39/18639	0.128205128205128	1.42408544971119	0.271894941482976	0.693537636914459
GO:0070888	E-box binding	7/1678	59/18639	0.11864406779661	1.31788246702087	0.279204475889532	0.710647599192967
GO:0008106	alcohol dehydrogenase (NADP+) activity	4/1678	30/18639	0.133333333333333	1.48104886769964	0.282640508775809	0.712287318113602
GO:0051721	protein phosphatase 2A binding	4/1678	30/18639	0.133333333333333	1.48104886769964	0.282640508775809	0.712287318113602
GO:0032182	ubiquitin-like protein binding	13/1678	120/18639	0.108333333333333	1.20335220500596	0.283229659392323	0.712287318113602
GO:0030331	nuclear estrogen receptor binding	5/1678	40/18639	0.125	1.38848331346841	0.289815376271069	0.712287318113602
GO:0071949	FAD binding	5/1678	40/18639	0.125	1.38848331346841	0.289815376271069	0.712287318113602
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/1678	21/18639	0.142857142857143	1.58683807253533	0.292058775795926	0.712287318113602
GO:0015174	basic amino acid transmembrane transporter activity	3/1678	21/18639	0.142857142857143	1.58683807253533	0.292058775795926	0.712287318113602
GO:0019200	carbohydrate kinase activity	3/1678	21/18639	0.142857142857143	1.58683807253533	0.292058775795926	0.712287318113602
GO:0048306	calcium-dependent protein binding	9/1678	80/18639	0.1125	1.24963498212157	0.292088669350533	0.712287318113602
GO:0046906	tetrapyrrole binding	16/1678	152/18639	0.105263157894737	1.16924910607867	0.2930053075268	0.712287318113602
GO:0003720	telomerase activity	2/1678	12/18639	0.166666666666667	1.85131108462455	0.294926755764226	0.712287318113602
GO:0003995	acyl-CoA dehydrogenase activity	2/1678	12/18639	0.166666666666667	1.85131108462455	0.294926755764226	0.712287318113602
GO:0004032	aldose reductase (NADPH) activity	2/1678	12/18639	0.166666666666667	1.85131108462455	0.294926755764226	0.712287318113602
GO:0004526	ribonuclease P activity	2/1678	12/18639	0.166666666666667	1.85131108462455	0.294926755764226	0.712287318113602
GO:0005078	MAP-kinase scaffold activity	2/1678	12/18639	0.166666666666667	1.85131108462455	0.294926755764226	0.712287318113602
GO:0008179	adenylate cyclase binding	2/1678	12/18639	0.166666666666667	1.85131108462455	0.294926755764226	0.712287318113602
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/1678	12/18639	0.166666666666667	1.85131108462455	0.294926755764226	0.712287318113602
GO:0010853	cyclase activator activity	2/1678	12/18639	0.166666666666667	1.85131108462455	0.294926755764226	0.712287318113602
GO:0015132	prostaglandin transmembrane transporter activity	2/1678	12/18639	0.166666666666667	1.85131108462455	0.294926755764226	0.712287318113602
GO:0016208	AMP binding	2/1678	12/18639	0.166666666666667	1.85131108462455	0.294926755764226	0.712287318113602
GO:0016423	tRNA (guanine) methyltransferase activity	2/1678	12/18639	0.166666666666667	1.85131108462455	0.294926755764226	0.712287318113602
GO:0035251	UDP-glucosyltransferase activity	2/1678	12/18639	0.166666666666667	1.85131108462455	0.294926755764226	0.712287318113602
GO:0036009	protein-glutamine N-methyltransferase activity	2/1678	12/18639	0.166666666666667	1.85131108462455	0.294926755764226	0.712287318113602
GO:0042301	phosphate ion binding	2/1678	12/18639	0.166666666666667	1.85131108462455	0.294926755764226	0.712287318113602
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/1678	12/18639	0.166666666666667	1.85131108462455	0.294926755764226	0.712287318113602
GO:0072341	modified amino acid binding	10/1678	91/18639	0.10989010989011	1.22064467118102	0.302182947684891	0.728322573909911
GO:0008327	methyl-CpG binding	4/1678	31/18639	0.129032258064516	1.43327309777385	0.303537157125945	0.728612566190532
GO:0017147	Wnt-protein binding	4/1678	31/18639	0.129032258064516	1.43327309777385	0.303537157125945	0.728612566190532
GO:0141003	histone H2AX kinase activity	35/1678	354/18639	0.0988700564971751	1.09823538918406	0.304415481716848	0.729238709751718
GO:0001530	lipopolysaccharide binding	5/1678	41/18639	0.121951219512195	1.35461786679845	0.307935901223024	0.734691513827054
GO:0061650	ubiquitin-like protein conjugating enzyme activity	5/1678	41/18639	0.121951219512195	1.35461786679845	0.307935901223024	0.734691513827054
GO:0043178	alcohol binding	10/1678	92/18639	0.108695652173913	1.20737679432036	0.314180713355588	0.746665136221185
GO:0034062	5'-3' RNA polymerase activity	3/1678	22/18639	0.136363636363636	1.51470906923827	0.317591837032174	0.746665136221185
GO:0061133	endopeptidase activator activity	3/1678	22/18639	0.136363636363636	1.51470906923827	0.317591837032174	0.746665136221185
GO:0097747	RNA polymerase activity	3/1678	22/18639	0.136363636363636	1.51470906923827	0.317591837032174	0.746665136221185
GO:0140035	ubiquitin-like protein reader activity	3/1678	22/18639	0.136363636363636	1.51470906923827	0.317591837032174	0.746665136221185
GO:0140784	metal ion sensor activity	3/1678	22/18639	0.136363636363636	1.51470906923827	0.317591837032174	0.746665136221185
GO:0016758	hexosyltransferase activity	20/1678	197/18639	0.101522842639594	1.12770218352765	0.319747382527458	0.746665136221185
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/1678	32/18639	0.125	1.38848331346841	0.324591425524326	0.746665136221185
GO:0042910	xenobiotic transmembrane transporter activity	4/1678	32/18639	0.125	1.38848331346841	0.324591425524326	0.746665136221185
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	6/1678	52/18639	0.115384615384615	1.28167690474008	0.325411003689707	0.746665136221185
GO:0004520	DNA endonuclease activity	5/1678	42/18639	0.119047619047619	1.32236506044611	0.326209132109934	0.746665136221185
GO:0048487	beta-tubulin binding	5/1678	42/18639	0.119047619047619	1.32236506044611	0.326209132109934	0.746665136221185
GO:0051213	dioxygenase activity	10/1678	93/18639	0.10752688172043	1.19439424814487	0.326283437974789	0.746665136221185
GO:0009982	pseudouridine synthase activity	2/1678	13/18639	0.153846153846154	1.70890253965343	0.329392494471835	0.746665136221185
GO:0019855	calcium channel inhibitor activity	2/1678	13/18639	0.153846153846154	1.70890253965343	0.329392494471835	0.746665136221185
GO:0030955	potassium ion binding	2/1678	13/18639	0.153846153846154	1.70890253965343	0.329392494471835	0.746665136221185
GO:0031432	titin binding	2/1678	13/18639	0.153846153846154	1.70890253965343	0.329392494471835	0.746665136221185
GO:0035673	oligopeptide transmembrane transporter activity	2/1678	13/18639	0.153846153846154	1.70890253965343	0.329392494471835	0.746665136221185
GO:0039706	co-receptor binding	2/1678	13/18639	0.153846153846154	1.70890253965343	0.329392494471835	0.746665136221185
GO:0043560	insulin receptor substrate binding	2/1678	13/18639	0.153846153846154	1.70890253965343	0.329392494471835	0.746665136221185
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/1678	13/18639	0.153846153846154	1.70890253965343	0.329392494471835	0.746665136221185
GO:0070700	BMP receptor binding	2/1678	13/18639	0.153846153846154	1.70890253965343	0.329392494471835	0.746665136221185
GO:0071714	icosanoid transmembrane transporter activity	2/1678	13/18639	0.153846153846154	1.70890253965343	0.329392494471835	0.746665136221185
GO:0071837	HMG box domain binding	2/1678	13/18639	0.153846153846154	1.70890253965343	0.329392494471835	0.746665136221185
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/1678	13/18639	0.153846153846154	1.70890253965343	0.329392494471835	0.746665136221185
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/1678	13/18639	0.153846153846154	1.70890253965343	0.329392494471835	0.746665136221185
GO:0004521	RNA endonuclease activity	8/1678	73/18639	0.10958904109589	1.21730043920519	0.334475679561478	0.756735206057675
GO:0140789	histone phosphatase activity	14/1678	136/18639	0.102941176470588	1.14345684638575	0.340062154935438	0.766640387126007
GO:0004022	alcohol dehydrogenase (NAD+) activity	3/1678	23/18639	0.130434782608696	1.44885215318443	0.343151230909329	0.766640387126007
GO:0005158	insulin receptor binding	3/1678	23/18639	0.130434782608696	1.44885215318443	0.343151230909329	0.766640387126007
GO:0031681	G-protein beta-subunit binding	3/1678	23/18639	0.130434782608696	1.44885215318443	0.343151230909329	0.766640387126007
GO:0043274	phospholipase binding	3/1678	23/18639	0.130434782608696	1.44885215318443	0.343151230909329	0.766640387126007
GO:0140103	catalytic activity, acting on a glycoprotein	3/1678	23/18639	0.130434782608696	1.44885215318443	0.343151230909329	0.766640387126007
GO:0004527	exonuclease activity	9/1678	84/18639	0.107142857142857	1.1901285544015	0.343397768661861	0.766640387126007
GO:0008200	ion channel inhibitor activity	5/1678	43/18639	0.116279069767442	1.29161238462178	0.344588948181374	0.767848203400383
GO:0140416	transcription regulator inhibitor activity	4/1678	33/18639	0.121212121212121	1.34640806154513	0.34573360163764	0.768947991589554
GO:0004519	endonuclease activity	13/1678	127/18639	0.102362204724409	1.13702570551744	0.35608212486773	0.777406090111318
GO:0050661	NADP binding	6/1678	54/18639	0.111111111111111	1.2342073897497	0.358371737819006	0.777406090111318
GO:0019003	GDP binding	8/1678	75/18639	0.106666666666667	1.18483909415971	0.362386902723563	0.777406090111318
GO:0001046	core promoter sequence-specific DNA binding	5/1678	44/18639	0.113636363636364	1.26225755769856	0.363030727744129	0.777406090111318
GO:0016248	channel inhibitor activity	5/1678	44/18639	0.113636363636364	1.26225755769856	0.363030727744129	0.777406090111318
GO:0030547	signaling receptor inhibitor activity	5/1678	44/18639	0.113636363636364	1.26225755769856	0.363030727744129	0.777406090111318
GO:0016407	acetyltransferase activity	10/1678	96/18639	0.104166666666667	1.15706942789035	0.363087779393103	0.777406090111318
GO:0005161	platelet-derived growth factor receptor binding	2/1678	14/18639	0.142857142857143	1.58683807253533	0.363370650115476	0.777406090111318
GO:0005545	1-phosphatidylinositol binding	2/1678	14/18639	0.142857142857143	1.58683807253533	0.363370650115476	0.777406090111318
GO:0008174	mRNA methyltransferase activity	2/1678	14/18639	0.142857142857143	1.58683807253533	0.363370650115476	0.777406090111318
GO:0008191	metalloendopeptidase inhibitor activity	2/1678	14/18639	0.142857142857143	1.58683807253533	0.363370650115476	0.777406090111318
GO:0008559	ABC-type xenobiotic transporter activity	2/1678	14/18639	0.142857142857143	1.58683807253533	0.363370650115476	0.777406090111318
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/1678	14/18639	0.142857142857143	1.58683807253533	0.363370650115476	0.777406090111318
GO:0030983	mismatched DNA binding	2/1678	14/18639	0.142857142857143	1.58683807253533	0.363370650115476	0.777406090111318
GO:0032036	myosin heavy chain binding	2/1678	14/18639	0.142857142857143	1.58683807253533	0.363370650115476	0.777406090111318
GO:0046030	inositol trisphosphate phosphatase activity	2/1678	14/18639	0.142857142857143	1.58683807253533	0.363370650115476	0.777406090111318
GO:1901612	cardiolipin binding	2/1678	14/18639	0.142857142857143	1.58683807253533	0.363370650115476	0.777406090111318
GO:0008175	tRNA methyltransferase activity	4/1678	34/18639	0.117647058823529	1.30680782444086	0.36689759489496	0.777406090111318
GO:0008376	acetylgalactosaminyltransferase activity	4/1678	34/18639	0.117647058823529	1.30680782444086	0.36689759489496	0.777406090111318
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	4/1678	34/18639	0.117647058823529	1.30680782444086	0.36689759489496	0.777406090111318
GO:0120013	lipid transfer activity	7/1678	65/18639	0.107692307692308	1.1962317777574	0.368552360488992	0.777406090111318
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	3/1678	24/18639	0.125	1.38848331346841	0.368626088452446	0.777406090111318
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	3/1678	24/18639	0.125	1.38848331346841	0.368626088452446	0.777406090111318
GO:0015149	hexose transmembrane transporter activity	3/1678	24/18639	0.125	1.38848331346841	0.368626088452446	0.777406090111318
GO:0015295	solute:proton symporter activity	3/1678	24/18639	0.125	1.38848331346841	0.368626088452446	0.777406090111318
GO:0030215	semaphorin receptor binding	3/1678	24/18639	0.125	1.38848331346841	0.368626088452446	0.777406090111318
GO:0055056	D-glucose transmembrane transporter activity	3/1678	24/18639	0.125	1.38848331346841	0.368626088452446	0.777406090111318
GO:0070300	phosphatidic acid binding	3/1678	24/18639	0.125	1.38848331346841	0.368626088452446	0.777406090111318
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	3/1678	24/18639	0.125	1.38848331346841	0.368626088452446	0.777406090111318
GO:0030295	protein kinase activator activity	14/1678	139/18639	0.100719424460432	1.11877792164361	0.370762737874168	0.780518348358988
GO:0141110	transporter inhibitor activity	5/1678	45/18639	0.111111111111111	1.2342073897497	0.381491549101324	0.801675301581252
GO:0034061	DNA polymerase activity	4/1678	35/18639	0.114285714285714	1.26947045802826	0.388021187017351	0.807701647641637
GO:0061631	ubiquitin conjugating enzyme activity	4/1678	35/18639	0.114285714285714	1.26947045802826	0.388021187017351	0.807701647641637
GO:0004674	protein serine/threonine kinase activity	41/1678	433/18639	0.0946882217090069	1.05178412659963	0.390286645974057	0.807701647641637
GO:0170055	lipid transmembrane transporter activity	6/1678	56/18639	0.107142857142857	1.1901285544015	0.391524763949191	0.807701647641637
GO:0005537	D-mannose binding	3/1678	25/18639	0.12	1.33294398092968	0.39391619682724	0.807701647641637
GO:0015662	P-type ion transporter activity	3/1678	25/18639	0.12	1.33294398092968	0.39391619682724	0.807701647641637
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	3/1678	25/18639	0.12	1.33294398092968	0.39391619682724	0.807701647641637
GO:0140358	P-type transmembrane transporter activity	3/1678	25/18639	0.12	1.33294398092968	0.39391619682724	0.807701647641637
GO:0000774	adenyl-nucleotide exchange factor activity	2/1678	15/18639	0.133333333333333	1.48104886769964	0.39666973381215	0.807701647641637
GO:0004559	alpha-mannosidase activity	2/1678	15/18639	0.133333333333333	1.48104886769964	0.39666973381215	0.807701647641637
GO:0005523	tropomyosin binding	2/1678	15/18639	0.133333333333333	1.48104886769964	0.39666973381215	0.807701647641637
GO:0031005	filamin binding	2/1678	15/18639	0.133333333333333	1.48104886769964	0.39666973381215	0.807701647641637
GO:0031386	protein tag activity	2/1678	15/18639	0.133333333333333	1.48104886769964	0.39666973381215	0.807701647641637
GO:0034483	heparan sulfate sulfotransferase activity	2/1678	15/18639	0.133333333333333	1.48104886769964	0.39666973381215	0.807701647641637
GO:0042809	nuclear vitamin D receptor binding	2/1678	15/18639	0.133333333333333	1.48104886769964	0.39666973381215	0.807701647641637
GO:0061578	K63-linked deubiquitinase activity	2/1678	15/18639	0.133333333333333	1.48104886769964	0.39666973381215	0.807701647641637
GO:0120283	protein serine/threonine kinase binding	2/1678	15/18639	0.133333333333333	1.48104886769964	0.39666973381215	0.807701647641637
GO:0141047	molecular tag activity	2/1678	15/18639	0.133333333333333	1.48104886769964	0.39666973381215	0.807701647641637
GO:0030291	protein serine/threonine kinase inhibitor activity	5/1678	46/18639	0.108695652173913	1.20737679432036	0.399930358523626	0.812939334623755
GO:0005516	calmodulin binding	20/1678	207/18639	0.0966183574879227	1.07322381717365	0.404301671734175	0.820412842470895
GO:0004540	RNA nuclease activity	12/1678	121/18639	0.0991735537190083	1.10160659580965	0.407197936216239	0.824872663244217
GO:0004033	aldo-keto reductase (NADPH) activity	4/1678	36/18639	0.111111111111111	1.2342073897497	0.40904620937834	0.827197899444896
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	33/1678	349/18639	0.0945558739255014	1.05031402508786	0.409904519238957	0.827516644822578
GO:0004252	serine-type endopeptidase activity	17/1678	176/18639	0.0965909090909091	1.07291892404378	0.4176855456997	0.838573647270691
GO:0004112	cyclic-nucleotide phosphodiesterase activity	3/1678	26/18639	0.115384615384615	1.28167690474008	0.418931796688999	0.838573647270691
GO:0004529	DNA exonuclease activity	3/1678	26/18639	0.115384615384615	1.28167690474008	0.418931796688999	0.838573647270691
GO:0015145	monosaccharide transmembrane transporter activity	3/1678	26/18639	0.115384615384615	1.28167690474008	0.418931796688999	0.838573647270691
GO:0030507	spectrin binding	3/1678	26/18639	0.115384615384615	1.28167690474008	0.418931796688999	0.838573647270691
GO:0005024	transforming growth factor beta receptor activity	2/1678	16/18639	0.125	1.38848331346841	0.429136646924909	0.85178215129129
GO:0015562	efflux transmembrane transporter activity	2/1678	16/18639	0.125	1.38848331346841	0.429136646924909	0.85178215129129
GO:0015923	mannosidase activity	2/1678	16/18639	0.125	1.38848331346841	0.429136646924909	0.85178215129129
GO:0019841	retinol binding	2/1678	16/18639	0.125	1.38848331346841	0.429136646924909	0.85178215129129
GO:0030275	LRR domain binding	2/1678	16/18639	0.125	1.38848331346841	0.429136646924909	0.85178215129129
GO:0030551	cyclic nucleotide binding	4/1678	37/18639	0.108108108108108	1.20085043326998	0.42991865537967	0.851902570475487
GO:0008194	UDP-glycosyltransferase activity	14/1678	145/18639	0.096551724137931	1.07248366281698	0.433058993448529	0.856687891562332
GO:0016879	ligase activity, forming carbon-nitrogen bonds	5/1678	48/18639	0.104166666666667	1.15706942789035	0.436587858661176	0.860761223720342
GO:0015459	potassium channel regulator activity	6/1678	59/18639	0.101694915254237	1.12961354316074	0.441091878463891	0.860761223720342
GO:0045309	protein phosphorylated amino acid binding	6/1678	59/18639	0.101694915254237	1.12961354316074	0.441091878463891	0.860761223720342
GO:0070063	RNA polymerase binding	6/1678	59/18639	0.101694915254237	1.12961354316074	0.441091878463891	0.860761223720342
GO:0001671	ATPase activator activity	3/1678	27/18639	0.111111111111111	1.2342073897497	0.443593256403358	0.860761223720342
GO:0016782	transferase activity, transferring sulphur-containing groups	7/1678	70/18639	0.1	1.11078665077473	0.444337455916422	0.860761223720342
GO:0016247	channel regulator activity	16/1678	168/18639	0.0952380952380952	1.05789204835689	0.445209020937173	0.860761223720342
GO:0019902	phosphatase binding	18/1678	190/18639	0.0947368421052632	1.0523241954708	0.446509587740449	0.860761223720342
GO:0033192	calmodulin-dependent protein phosphatase activity	8/1678	81/18639	0.0987654320987654	1.09707323533307	0.446779534411998	0.860761223720342
GO:0140791	histone H2AXS140 phosphatase activity	8/1678	81/18639	0.0987654320987654	1.09707323533307	0.446779534411998	0.860761223720342
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	8/1678	81/18639	0.0987654320987654	1.09707323533307	0.446779534411998	0.860761223720342
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	8/1678	81/18639	0.0987654320987654	1.09707323533307	0.446779534411998	0.860761223720342
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	8/1678	81/18639	0.0987654320987654	1.09707323533307	0.446779534411998	0.860761223720342
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	8/1678	81/18639	0.0987654320987654	1.09707323533307	0.446779534411998	0.860761223720342
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	8/1678	81/18639	0.0987654320987654	1.09707323533307	0.446779534411998	0.860761223720342
GO:1990439	MAP kinase serine/threonine phosphatase activity	8/1678	81/18639	0.0987654320987654	1.09707323533307	0.446779534411998	0.860761223720342
GO:0001222	transcription corepressor binding	5/1678	49/18639	0.102040816326531	1.13345576609667	0.454734870352075	0.869247595487522
GO:0060590	ATPase regulator activity	5/1678	49/18639	0.102040816326531	1.13345576609667	0.454734870352075	0.869247595487522
GO:0001098	basal transcription machinery binding	6/1678	60/18639	0.1	1.11078665077473	0.457460687235134	0.869247595487522
GO:0001099	basal RNA polymerase II transcription machinery binding	6/1678	60/18639	0.1	1.11078665077473	0.457460687235134	0.869247595487522
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6/1678	60/18639	0.1	1.11078665077473	0.457460687235134	0.869247595487522
GO:0004549	tRNA-specific ribonuclease activity	2/1678	17/18639	0.117647058823529	1.30680782444086	0.46065132742519	0.869247595487522
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	2/1678	17/18639	0.117647058823529	1.30680782444086	0.46065132742519	0.869247595487522
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/1678	17/18639	0.117647058823529	1.30680782444086	0.46065132742519	0.869247595487522
GO:0030548	acetylcholine receptor regulator activity	2/1678	17/18639	0.117647058823529	1.30680782444086	0.46065132742519	0.869247595487522
GO:0038191	neuropilin binding	2/1678	17/18639	0.117647058823529	1.30680782444086	0.46065132742519	0.869247595487522
GO:0048038	quinone binding	2/1678	17/18639	0.117647058823529	1.30680782444086	0.46065132742519	0.869247595487522
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	8/1678	82/18639	0.0975609756097561	1.08369429343876	0.460752747481108	0.869247595487522
GO:0033549	MAP kinase phosphatase activity	8/1678	82/18639	0.0975609756097561	1.08369429343876	0.460752747481108	0.869247595487522
GO:0051219	phosphoprotein binding	9/1678	93/18639	0.0967741935483871	1.07495482333039	0.461787233442766	0.869809765065242
GO:0019209	kinase activator activity	14/1678	148/18639	0.0945945945945946	1.05074412911123	0.464256759087961	0.871463725197952
GO:0141108	transporter regulator activity	16/1678	170/18639	0.0941176470588235	1.04544625955269	0.46459927750922	0.871463725197952
GO:0046966	nuclear thyroid hormone receptor binding	3/1678	28/18639	0.107142857142857	1.1901285544015	0.467830653493227	0.871463725197952
GO:0050698	proteoglycan sulfotransferase activity	3/1678	28/18639	0.107142857142857	1.1901285544015	0.467830653493227	0.871463725197952
GO:0051119	sugar transmembrane transporter activity	3/1678	28/18639	0.107142857142857	1.1901285544015	0.467830653493227	0.871463725197952
GO:0051393	alpha-actinin binding	3/1678	28/18639	0.107142857142857	1.1901285544015	0.467830653493227	0.871463725197952
GO:0051537	2 iron, 2 sulfur cluster binding	3/1678	28/18639	0.107142857142857	1.1901285544015	0.467830653493227	0.871463725197952
GO:0015605	organophosphate ester transmembrane transporter activity	5/1678	50/18639	0.1	1.11078665077473	0.472716648897256	0.879008112927586
GO:0016836	hydro-lyase activity	6/1678	61/18639	0.0983606557377049	1.09257703354892	0.473710555848989	0.879008112927586
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	8/1678	83/18639	0.0963855421686747	1.07063773568649	0.474655269962143	0.879008112927586
GO:0042826	histone deacetylase binding	12/1678	127/18639	0.094488188976378	1.04956218970841	0.474857896738188	0.879008112927586
GO:0051020	GTPase binding	29/1678	315/18639	0.0920634920634921	1.02262898007832	0.478299504053706	0.883993293094565
GO:0017018	myosin phosphatase activity	8/1678	84/18639	0.0952380952380952	1.05789204835689	0.488471849046383	0.887706213846976
GO:0030544	Hsp70 protein binding	5/1678	51/18639	0.0980392156862745	1.08900652036738	0.49050298384232	0.887706213846976
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/1678	18/18639	0.111111111111111	1.2342073897497	0.491122048171759	0.887706213846976
GO:0008308	voltage-gated monoatomic anion channel activity	2/1678	18/18639	0.111111111111111	1.2342073897497	0.491122048171759	0.887706213846976
GO:0008409	5'-3' exonuclease activity	2/1678	18/18639	0.111111111111111	1.2342073897497	0.491122048171759	0.887706213846976
GO:0016854	racemase and epimerase activity	2/1678	18/18639	0.111111111111111	1.2342073897497	0.491122048171759	0.887706213846976
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/1678	18/18639	0.111111111111111	1.2342073897497	0.491122048171759	0.887706213846976
GO:0034185	apolipoprotein binding	2/1678	18/18639	0.111111111111111	1.2342073897497	0.491122048171759	0.887706213846976
GO:0099602	neurotransmitter receptor regulator activity	2/1678	18/18639	0.111111111111111	1.2342073897497	0.491122048171759	0.887706213846976
GO:0004532	RNA exonuclease activity	4/1678	40/18639	0.1	1.11078665077473	0.491143717717551	0.887706213846976
GO:0061791	GTPase motor activity	4/1678	40/18639	0.1	1.11078665077473	0.491143717717551	0.887706213846976
GO:1990606	membrane scission GTPase motor activity	4/1678	40/18639	0.1	1.11078665077473	0.491143717717551	0.887706213846976
GO:0004629	phospholipase C activity	3/1678	29/18639	0.103448275862069	1.14908963873248	0.491583288616361	0.887706213846976
GO:0016417	S-acyltransferase activity	3/1678	29/18639	0.103448275862069	1.14908963873248	0.491583288616361	0.887706213846976
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	3/1678	29/18639	0.103448275862069	1.14908963873248	0.491583288616361	0.887706213846976
GO:0016791	phosphatase activity	25/1678	273/18639	0.0915750915750916	1.01720389265085	0.495221806456125	0.892859729542956
GO:0003730	mRNA 3'-UTR binding	24/1678	262/18639	0.0916030534351145	1.0175144892593	0.495949180846892	0.892859729542956
GO:0035591	signaling adaptor activity	12/1678	129/18639	0.0930232558139535	1.03328990769742	0.497170912243311	0.893696875737216
GO:0015078	proton transmembrane transporter activity	17/1678	185/18639	0.0918918918918919	1.02072286827948	0.502042605791129	0.899715200970142
GO:1901981	phosphatidylinositol phosphate binding	17/1678	185/18639	0.0918918918918919	1.02072286827948	0.502042605791129	0.899715200970142
GO:0035064	methylated histone binding	7/1678	74/18639	0.0945945945945946	1.05074412911123	0.5038403625868	0.901568891234865
GO:0005507	copper ion binding	6/1678	63/18639	0.0952380952380952	1.05789204835689	0.505761989541864	0.903638289937884
GO:0030159	signaling receptor complex adaptor activity	5/1678	52/18639	0.0961538461538462	1.0680640872834	0.5080659604543	0.906383533680557
GO:0008137	NADH dehydrogenase (ubiquinone) activity	4/1678	41/18639	0.0975609756097561	1.08369429343876	0.510949968149392	0.907416409600649
GO:0015175	neutral L-amino acid transmembrane transporter activity	4/1678	41/18639	0.0975609756097561	1.08369429343876	0.510949968149392	0.907416409600649
GO:0017080	sodium channel regulator activity	4/1678	41/18639	0.0975609756097561	1.08369429343876	0.510949968149392	0.907416409600649
GO:0004721	phosphoprotein phosphatase activity	16/1678	175/18639	0.0914285714285714	1.01557636642261	0.51265496599403	0.90878594879505
GO:0001965	G-protein alpha-subunit binding	3/1678	30/18639	0.1	1.11078665077473	0.514799153043089	0.90878594879505
GO:0015215	nucleotide transmembrane transporter activity	3/1678	30/18639	0.1	1.11078665077473	0.514799153043089	0.90878594879505
GO:0033612	receptor serine/threonine kinase binding	3/1678	30/18639	0.1	1.11078665077473	0.514799153043089	0.90878594879505
GO:0004518	nuclease activity	19/1678	209/18639	0.0909090909090909	1.00980604615885	0.517572203965961	0.909302377653066
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/1678	19/18639	0.105263157894737	1.16924910607867	0.520481293220553	0.909302377653066
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/1678	19/18639	0.105263157894737	1.16924910607867	0.520481293220553	0.909302377653066
GO:0016918	retinal binding	2/1678	19/18639	0.105263157894737	1.16924910607867	0.520481293220553	0.909302377653066
GO:0030506	ankyrin binding	2/1678	19/18639	0.105263157894737	1.16924910607867	0.520481293220553	0.909302377653066
GO:0046527	glucosyltransferase activity	2/1678	19/18639	0.105263157894737	1.16924910607867	0.520481293220553	0.909302377653066
GO:0070003	threonine-type peptidase activity	2/1678	19/18639	0.105263157894737	1.16924910607867	0.520481293220553	0.909302377653066
GO:0004536	DNA nuclease activity	6/1678	64/18639	0.09375	1.04136248510131	0.521521395151373	0.909773659784005
GO:0005246	calcium channel regulator activity	5/1678	53/18639	0.0943396226415094	1.04791193469314	0.525379954210669	0.911121477125991
GO:0017046	peptide hormone binding	5/1678	53/18639	0.0943396226415094	1.04791193469314	0.525379954210669	0.911121477125991
GO:0051018	protein kinase A binding	5/1678	53/18639	0.0943396226415094	1.04791193469314	0.525379954210669	0.911121477125991
GO:1901505	carbohydrate derivative transmembrane transporter activity	5/1678	53/18639	0.0943396226415094	1.04791193469314	0.525379954210669	0.911121477125991
GO:0042626	ATPase-coupled transmembrane transporter activity	9/1678	98/18639	0.0918367346938776	1.020110189487	0.526250006319302	0.911292166368176
GO:0046943	carboxylic acid transmembrane transporter activity	17/1678	188/18639	0.0904255319148936	1.00443473740268	0.529693661989586	0.91296915554505
GO:0140034	methylation-dependent protein binding	7/1678	76/18639	0.0921052631578947	1.02309296781883	0.532804653181908	0.91296915554505
GO:0022804	active transmembrane transporter activity	41/1678	457/18639	0.0897155361050328	0.996548198725689	0.533804086028912	0.91296915554505
GO:0047499	calcium-independent phospholipase A2 activity	3/1678	31/18639	0.0967741935483871	1.07495482333039	0.537434366891354	0.91296915554505
GO:0005342	organic acid transmembrane transporter activity	17/1678	189/18639	0.0899470899470899	0.999120267892616	0.538817966760728	0.91296915554505
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	5/1678	54/18639	0.0925925925925926	1.02850615812475	0.542421608944512	0.91296915554505
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	15/1678	167/18639	0.0898203592814371	0.997712560576106	0.543344535931559	0.91296915554505
GO:1902936	phosphatidylinositol bisphosphate binding	10/1678	111/18639	0.0900900900900901	1.00070869439165	0.547439958491638	0.91296915554505
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/1678	20/18639	0.1	1.11078665077473	0.54868214628783	0.91296915554505
GO:0005326	neurotransmitter transmembrane transporter activity	2/1678	20/18639	0.1	1.11078665077473	0.54868214628783	0.91296915554505
GO:0052745	inositol phosphate phosphatase activity	2/1678	20/18639	0.1	1.11078665077473	0.54868214628783	0.91296915554505
GO:0008235	metalloexopeptidase activity	6/1678	66/18639	0.0909090909090909	1.00980604615885	0.552413053578614	0.91296915554505
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	8/1678	89/18639	0.0898876404494382	0.998459910808748	0.555779833246427	0.91296915554505
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	8/1678	89/18639	0.0898876404494382	0.998459910808748	0.555779833246427	0.91296915554505
GO:0140313	molecular sequestering activity	5/1678	55/18639	0.0909090909090909	1.00980604615885	0.559169800607006	0.91296915554505
GO:0015106	bicarbonate transmembrane transporter activity	3/1678	32/18639	0.09375	1.04136248510131	0.559452602205185	0.91296915554505
GO:0047498	calcium-dependent phospholipase A2 activity	3/1678	32/18639	0.09375	1.04136248510131	0.559452602205185	0.91296915554505
GO:0120015	sterol transfer activity	3/1678	32/18639	0.09375	1.04136248510131	0.559452602205185	0.91296915554505
GO:0106310	protein serine kinase activity	32/1678	361/18639	0.0886426592797784	0.984630826171507	0.564266113285009	0.91296915554505
GO:0008173	RNA methyltransferase activity	6/1678	67/18639	0.0895522388059701	0.994734314126625	0.567511837525665	0.91296915554505
GO:0001223	transcription coactivator binding	4/1678	44/18639	0.0909090909090909	1.00980604615885	0.568095825197554	0.91296915554505
GO:0003954	NADH dehydrogenase activity	4/1678	44/18639	0.0909090909090909	1.00980604615885	0.568095825197554	0.91296915554505
GO:0043014	alpha-tubulin binding	4/1678	44/18639	0.0909090909090909	1.00980604615885	0.568095825197554	0.91296915554505
GO:0140793	histone H2AXY142 phosphatase activity	8/1678	90/18639	0.0888888888888889	0.987365911799762	0.568799316602207	0.91296915554505
GO:0016741	transferase activity, transferring one-carbon groups	19/1678	215/18639	0.0883720930232558	0.981625412312554	0.569035174113264	0.91296915554505
GO:0005543	phospholipid binding	44/1678	497/18639	0.0885311871227364	0.983392608331754	0.570457003717858	0.91296915554505
GO:0008186	ATP-dependent activity, acting on RNA	7/1678	79/18639	0.0886075949367089	0.984241336129509	0.574921189586145	0.91296915554505
GO:0033293	monocarboxylic acid binding	7/1678	79/18639	0.0886075949367089	0.984241336129509	0.574921189586145	0.91296915554505
GO:0001846	opsonin binding	2/1678	21/18639	0.0952380952380952	1.05789204835689	0.575695132655399	0.91296915554505
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	2/1678	21/18639	0.0952380952380952	1.05789204835689	0.575695132655399	0.91296915554505
GO:0035613	RNA stem-loop binding	2/1678	21/18639	0.0952380952380952	1.05789204835689	0.575695132655399	0.91296915554505
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/1678	21/18639	0.0952380952380952	1.05789204835689	0.575695132655399	0.91296915554505
GO:0051010	microtubule plus-end binding	2/1678	21/18639	0.0952380952380952	1.05789204835689	0.575695132655399	0.91296915554505
GO:0051428	peptide hormone receptor binding	2/1678	21/18639	0.0952380952380952	1.05789204835689	0.575695132655399	0.91296915554505
GO:0061891	calcium ion sensor activity	2/1678	21/18639	0.0952380952380952	1.05789204835689	0.575695132655399	0.91296915554505
GO:1904047	S-adenosyl-L-methionine binding	2/1678	21/18639	0.0952380952380952	1.05789204835689	0.575695132655399	0.91296915554505
GO:0019956	chemokine binding	3/1678	33/18639	0.0909090909090909	1.00980604615885	0.58082450226194	0.91296915554505
GO:0071889	14-3-3 protein binding	3/1678	33/18639	0.0909090909090909	1.00980604615885	0.58082450226194	0.91296915554505
GO:0008236	serine-type peptidase activity	17/1678	194/18639	0.0876288659793814	0.973369745524249	0.583555948620742	0.91296915554505
GO:0099106	ion channel regulator activity	14/1678	160/18639	0.0875	0.97193831942789	0.58516470462842	0.91296915554505
GO:0004715	non-membrane spanning protein tyrosine kinase activity	4/1678	45/18639	0.0888888888888889	0.987365911799762	0.586301120426455	0.91296915554505
GO:0004722	protein serine/threonine phosphatase activity	9/1678	103/18639	0.087378640776699	0.970590277375979	0.587840541687141	0.91296915554505
GO:0008237	metallopeptidase activity	16/1678	184/18639	0.0869565217391304	0.965901435456288	0.595957827500075	0.91296915554505
GO:0005243	gap junction channel activity	2/1678	22/18639	0.0909090909090909	1.00980604615885	0.601505462217721	0.91296915554505
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	2/1678	22/18639	0.0909090909090909	1.00980604615885	0.601505462217721	0.91296915554505
GO:0033691	sialic acid binding	2/1678	22/18639	0.0909090909090909	1.00980604615885	0.601505462217721	0.91296915554505
GO:0050321	tau-protein kinase activity	2/1678	22/18639	0.0909090909090909	1.00980604615885	0.601505462217721	0.91296915554505
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	3/1678	34/18639	0.0882352941176471	0.980105868330646	0.601527106200679	0.91296915554505
GO:0008083	growth factor activity	14/1678	162/18639	0.0864197530864197	0.959939080916435	0.604256606097595	0.91296915554505
GO:0008408	3'-5' exonuclease activity	5/1678	58/18639	0.0862068965517241	0.957574698943734	0.607474741040645	0.91296915554505
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	5/1678	58/18639	0.0862068965517241	0.957574698943734	0.607474741040645	0.91296915554505
GO:0004090	carbonyl reductase (NADPH) activity	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0004955	prostaglandin receptor activity	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0005031	tumor necrosis factor receptor activity	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0008190	eukaryotic initiation factor 4E binding	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0008239	dipeptidyl-peptidase activity	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0016783	sulfurtransferase activity	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0019911	structural constituent of myelin sheath	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0031434	mitogen-activated protein kinase kinase binding	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0032052	bile acid binding	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0042975	peroxisome proliferator activated receptor binding	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0043121	neurotrophin binding	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0050815	phosphoserine residue binding	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0099122	RNA polymerase II C-terminal domain binding	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0140135	mechanosensitive monoatomic cation channel activity	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0141109	transporter activator activity	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:1990757	ubiquitin ligase activator activity	1/1678	10/18639	0.1	1.11078665077473	0.610789373907538	0.91296915554505
GO:0046982	protein heterodimerization activity	32/1678	369/18639	0.0867208672086721	0.963283816390011	0.615584457448703	0.91296915554505
GO:0017171	serine hydrolase activity	17/1678	198/18639	0.0858585858585859	0.953705710261133	0.618060996737124	0.91296915554505
GO:0042562	hormone binding	8/1678	94/18639	0.0851063829787234	0.945350341084878	0.619055891829294	0.91296915554505
GO:0001784	phosphotyrosine residue binding	4/1678	47/18639	0.0851063829787234	0.945350341084878	0.621329099093299	0.91296915554505
GO:0005504	fatty acid binding	4/1678	47/18639	0.0851063829787234	0.945350341084878	0.621329099093299	0.91296915554505
GO:0043495	protein-membrane adaptor activity	4/1678	47/18639	0.0851063829787234	0.945350341084878	0.621329099093299	0.91296915554505
GO:0000175	3'-5'-RNA exonuclease activity	3/1678	35/18639	0.0857142857142857	0.952102843521199	0.621543286124116	0.91296915554505
GO:0004623	phospholipase A2 activity	3/1678	35/18639	0.0857142857142857	0.952102843521199	0.621543286124116	0.91296915554505
GO:0043015	gamma-tubulin binding	3/1678	35/18639	0.0857142857142857	0.952102843521199	0.621543286124116	0.91296915554505
GO:0001786	phosphatidylserine binding	5/1678	59/18639	0.0847457627118644	0.94134461930062	0.622880561649603	0.91296915554505
GO:0004879	nuclear receptor activity	5/1678	59/18639	0.0847457627118644	0.94134461930062	0.622880561649603	0.91296915554505
GO:0008013	beta-catenin binding	9/1678	106/18639	0.0849056603773585	0.943120741223829	0.622930198847371	0.91296915554505
GO:0000295	adenine nucleotide transmembrane transporter activity	2/1678	23/18639	0.0869565217391304	0.965901435456288	0.626110627104234	0.91296915554505
GO:0003887	DNA-directed DNA polymerase activity	2/1678	23/18639	0.0869565217391304	0.965901435456288	0.626110627104234	0.91296915554505
GO:0005212	structural constituent of eye lens	2/1678	23/18639	0.0869565217391304	0.965901435456288	0.626110627104234	0.91296915554505
GO:0005283	amino acid:sodium symporter activity	2/1678	23/18639	0.0869565217391304	0.965901435456288	0.626110627104234	0.91296915554505
GO:0042171	lysophosphatidic acid acyltransferase activity	2/1678	23/18639	0.0869565217391304	0.965901435456288	0.626110627104234	0.91296915554505
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	2/1678	23/18639	0.0869565217391304	0.965901435456288	0.626110627104234	0.91296915554505
GO:0070577	lysine-acetylated histone binding	2/1678	23/18639	0.0869565217391304	0.965901435456288	0.626110627104234	0.91296915554505
GO:0071617	lysophospholipid acyltransferase activity	2/1678	23/18639	0.0869565217391304	0.965901435456288	0.626110627104234	0.91296915554505
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	2/1678	23/18639	0.0869565217391304	0.965901435456288	0.626110627104234	0.91296915554505
GO:0004175	endopeptidase activity	35/1678	405/18639	0.0864197530864197	0.959939080916435	0.626890452276843	0.91296915554505
GO:0008276	protein methyltransferase activity	8/1678	95/18639	0.0842105263157895	0.935399284862932	0.631122637653699	0.91296915554505
GO:0098531	ligand-modulated transcription factor activity	5/1678	60/18639	0.0833333333333333	0.925655542312277	0.637918732050918	0.91296915554505
GO:0032266	phosphatidylinositol-3-phosphate binding	4/1678	48/18639	0.0833333333333333	0.925655542312277	0.638123757314401	0.91296915554505
GO:0004190	aspartic-type endopeptidase activity	3/1678	36/18639	0.0833333333333333	0.925655542312277	0.640861202191914	0.91296915554505
GO:0035402	histone H3T11 kinase activity	21/1678	247/18639	0.0850202429149798	0.944393508755845	0.641624805222533	0.91296915554505
GO:0035403	histone H3T6 kinase activity	21/1678	247/18639	0.0850202429149798	0.944393508755845	0.641624805222533	0.91296915554505
GO:0004016	adenylate cyclase activity	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0004954	prostanoid receptor activity	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0005225	volume-sensitive anion channel activity	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0008172	S-methyltransferase activity	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0008271	secondary active sulfate transmembrane transporter activity	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0015173	aromatic amino acid transmembrane transporter activity	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0015217	ADP transmembrane transporter activity	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0016594	glycine binding	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0019107	myristoyltransferase activity	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0019206	nucleoside kinase activity	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0032050	clathrin heavy chain binding	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0034713	type I transforming growth factor beta receptor binding	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0035252	UDP-xylosyltransferase activity	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0042285	xylosyltransferase activity	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0042608	T cell receptor binding	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0043522	leucine zipper domain binding	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0070697	activin receptor binding	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0140537	transcription regulator activator activity	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/1678	11/18639	0.0909090909090909	1.00980604615885	0.645847371147495	0.91296915554505
GO:0042578	phosphoric ester hydrolase activity	31/1678	363/18639	0.0853994490358127	0.948605679724978	0.649114643926219	0.91296915554505
GO:0004622	lysophospholipase activity	2/1678	24/18639	0.0833333333333333	0.925655542312277	0.649518312436216	0.91296915554505
GO:0004806	triacylglycerol lipase activity	2/1678	24/18639	0.0833333333333333	0.925655542312277	0.649518312436216	0.91296915554505
GO:0035035	histone acetyltransferase binding	2/1678	24/18639	0.0833333333333333	0.925655542312277	0.649518312436216	0.91296915554505
GO:0042625	ATPase-coupled ion transmembrane transporter activity	2/1678	24/18639	0.0833333333333333	0.925655542312277	0.649518312436216	0.91296915554505
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	2/1678	24/18639	0.0833333333333333	0.925655542312277	0.649518312436216	0.91296915554505
GO:0046961	proton-transporting ATPase activity, rotational mechanism	2/1678	24/18639	0.0833333333333333	0.925655542312277	0.649518312436216	0.91296915554505
GO:0070840	dynein complex binding	2/1678	24/18639	0.0833333333333333	0.925655542312277	0.649518312436216	0.91296915554505
GO:0140033	acetylation-dependent protein binding	2/1678	24/18639	0.0833333333333333	0.925655542312277	0.649518312436216	0.91296915554505
GO:0019905	syntaxin binding	5/1678	61/18639	0.0819672131147541	0.910480861290764	0.652580176354662	0.91296915554505
GO:0035254	glutamate receptor binding	4/1678	49/18639	0.0816326530612245	0.906764612877332	0.654424991711053	0.91296915554505
GO:0042277	peptide binding	21/1678	249/18639	0.0843373493975904	0.936808018725677	0.65632016066441	0.91296915554505
GO:0035091	phosphatidylinositol binding	24/1678	284/18639	0.0845070422535211	0.938692944316675	0.658716003471457	0.91296915554505
GO:0042805	actinin binding	3/1678	37/18639	0.0810810810810811	0.900637824952485	0.659473779851818	0.91296915554505
GO:0070001	aspartic-type peptidase activity	3/1678	37/18639	0.0810810810810811	0.900637824952485	0.659473779851818	0.91296915554505
GO:0004725	protein tyrosine phosphatase activity	8/1678	98/18639	0.0816326530612245	0.906764612877332	0.666020198462568	0.91296915554505
GO:0015179	L-amino acid transmembrane transporter activity	5/1678	62/18639	0.0806451612903226	0.895795686108655	0.666857537686819	0.91296915554505
GO:0004222	metalloendopeptidase activity	9/1678	110/18639	0.0818181818181818	0.908825441542962	0.667151342740956	0.91296915554505
GO:0008168	methyltransferase activity	17/1678	204/18639	0.0833333333333333	0.925655542312277	0.667198427655819	0.91296915554505
GO:0001664	G protein-coupled receptor binding	25/1678	297/18639	0.0841750841750842	0.935005598295229	0.668409686138995	0.91296915554505
GO:0000030	mannosyltransferase activity	2/1678	25/18639	0.08	0.888629320619786	0.671744583358735	0.91296915554505
GO:0001848	complement binding	2/1678	25/18639	0.08	0.888629320619786	0.671744583358735	0.91296915554505
GO:0004709	MAP kinase kinase kinase activity	2/1678	25/18639	0.08	0.888629320619786	0.671744583358735	0.91296915554505
GO:0017025	TBP-class protein binding	2/1678	25/18639	0.08	0.888629320619786	0.671744583358735	0.91296915554505
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/1678	25/18639	0.08	0.888629320619786	0.671744583358735	0.91296915554505
GO:0019707	protein-cysteine S-acyltransferase activity	2/1678	25/18639	0.08	0.888629320619786	0.671744583358735	0.91296915554505
GO:0120020	cholesterol transfer activity	2/1678	25/18639	0.08	0.888629320619786	0.671744583358735	0.91296915554505
GO:0008081	phosphoric diester hydrolase activity	7/1678	87/18639	0.0804597701149425	0.893736385680819	0.677302155430514	0.91296915554505
GO:0005501	retinoid binding	3/1678	38/18639	0.0789473684210526	0.876936829558999	0.677378212210581	0.91296915554505
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	3/1678	38/18639	0.0789473684210526	0.876936829558999	0.677378212210581	0.91296915554505
GO:0019840	isoprenoid binding	3/1678	38/18639	0.0789473684210526	0.876936829558999	0.677378212210581	0.91296915554505
GO:0000340	RNA 7-methylguanosine cap binding	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0004000	adenosine deaminase activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0004300	enoyl-CoA hydratase activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0004875	complement receptor activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0005025	transforming growth factor beta receptor activity, type I	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0005026	transforming growth factor beta receptor activity, type II	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0005165	neurotrophin receptor binding	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0008603	cAMP-dependent protein kinase regulator activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0016273	arginine N-methyltransferase activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0016274	protein-arginine N-methyltransferase activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0016361	activin receptor activity, type I	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0016362	activin receptor activity, type II	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0017002	activin receptor activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0035259	nuclear glucocorticoid receptor binding	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0035497	cAMP response element binding	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0097677	STAT family protein binding	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0140900	chloride:bicarbonate antiporter activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:1990817	poly(A) RNA polymerase activity	1/1678	12/18639	0.0833333333333333	0.925655542312277	0.677749245273247	0.91296915554505
GO:0016597	amino acid binding	4/1678	51/18639	0.0784313725490196	0.871205216293907	0.685521268945956	0.91296915554505
GO:0004197	cysteine-type endopeptidase activity	7/1678	88/18639	0.0795454545454545	0.883580290388991	0.688943290050717	0.91296915554505
GO:0016779	nucleotidyltransferase activity	11/1678	136/18639	0.0808823529411765	0.898430379303092	0.68930205185633	0.91296915554505
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	2/1678	26/18639	0.0769230769230769	0.854451269826717	0.692812315581213	0.91296915554505
GO:0008157	protein phosphatase 1 binding	2/1678	26/18639	0.0769230769230769	0.854451269826717	0.692812315581213	0.91296915554505
GO:0015216	purine nucleotide transmembrane transporter activity	2/1678	26/18639	0.0769230769230769	0.854451269826717	0.692812315581213	0.91296915554505
GO:0034237	protein kinase A regulatory subunit binding	2/1678	26/18639	0.0769230769230769	0.854451269826717	0.692812315581213	0.91296915554505
GO:0097602	cullin family protein binding	2/1678	26/18639	0.0769230769230769	0.854451269826717	0.692812315581213	0.91296915554505
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	20/1678	243/18639	0.0823045267489712	0.91422769611089	0.696457100591738	0.91296915554505
GO:0003724	RNA helicase activity	6/1678	77/18639	0.0779220779220779	0.865548039564726	0.702935847937966	0.91296915554505
GO:0002161	aminoacyl-tRNA editing activity	1/1678	13/18639	0.0769230769230769	0.854451269826717	0.706778974506698	0.91296915554505
GO:0004465	lipoprotein lipase activity	1/1678	13/18639	0.0769230769230769	0.854451269826717	0.706778974506698	0.91296915554505
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/1678	13/18639	0.0769230769230769	0.854451269826717	0.706778974506698	0.91296915554505
GO:0005035	death receptor activity	1/1678	13/18639	0.0769230769230769	0.854451269826717	0.706778974506698	0.91296915554505
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/1678	13/18639	0.0769230769230769	0.854451269826717	0.706778974506698	0.91296915554505
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/1678	13/18639	0.0769230769230769	0.854451269826717	0.706778974506698	0.91296915554505
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/1678	13/18639	0.0769230769230769	0.854451269826717	0.706778974506698	0.91296915554505
GO:0045159	myosin II binding	1/1678	13/18639	0.0769230769230769	0.854451269826717	0.706778974506698	0.91296915554505
GO:0070123	transforming growth factor beta receptor activity, type III	1/1678	13/18639	0.0769230769230769	0.854451269826717	0.706778974506698	0.91296915554505
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/1678	13/18639	0.0769230769230769	0.854451269826717	0.706778974506698	0.91296915554505
GO:0140852	histone ubiquitin ligase activity	1/1678	13/18639	0.0769230769230769	0.854451269826717	0.706778974506698	0.91296915554505
GO:1901338	catecholamine binding	1/1678	13/18639	0.0769230769230769	0.854451269826717	0.706778974506698	0.91296915554505
GO:0008238	exopeptidase activity	8/1678	102/18639	0.0784313725490196	0.871205216293907	0.709332196661222	0.91296915554505
GO:0004676	3-phosphoinositide-dependent protein kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:0004711	ribosomal protein S6 kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:0035175	histone H3S10 kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:0035979	histone H2AXS139 kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:0044022	histone H3S28 kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:0044023	histone H4S1 kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:0044024	histone H2AS1 kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:0044025	histone H2BS14 kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:0072354	histone H3T3 kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:0072371	histone H2AS121 kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:0072518	Rho-dependent protein serine/threonine kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:0140823	histone H2BS36 kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:0140855	histone H3S57 kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:0140995	histone H2A kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:0140997	histone H4 kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:0140998	histone H2B kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:1990244	histone H2AT120 kinase activity	20/1678	245/18639	0.0816326530612245	0.906764612877332	0.710191123991447	0.91296915554505
GO:0015144	carbohydrate transmembrane transporter activity	3/1678	40/18639	0.075	0.833089988081049	0.711069957587285	0.91296915554505
GO:0032451	demethylase activity	3/1678	40/18639	0.075	0.833089988081049	0.711069957587285	0.91296915554505
GO:0005104	fibroblast growth factor receptor binding	2/1678	27/18639	0.0740740740740741	0.822804926499801	0.712749840315441	0.91296915554505
GO:0005385	zinc ion transmembrane transporter activity	2/1678	27/18639	0.0740740740740741	0.822804926499801	0.712749840315441	0.91296915554505
GO:0023026	MHC class II protein complex binding	2/1678	27/18639	0.0740740740740741	0.822804926499801	0.712749840315441	0.91296915554505
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	2/1678	27/18639	0.0740740740740741	0.822804926499801	0.712749840315441	0.91296915554505
GO:0035255	ionotropic glutamate receptor binding	2/1678	27/18639	0.0740740740740741	0.822804926499801	0.712749840315441	0.91296915554505
GO:0008146	sulfotransferase activity	4/1678	53/18639	0.0754716981132075	0.838329547754515	0.714589150676145	0.913356466681923
GO:0070851	growth factor receptor binding	11/1678	139/18639	0.079136690647482	0.879039795577126	0.716488153823983	0.913356466681923
GO:0140101	catalytic activity, acting on a tRNA	11/1678	139/18639	0.079136690647482	0.879039795577126	0.716488153823983	0.913356466681923
GO:0004677	DNA-dependent protein kinase activity	20/1678	246/18639	0.0813008130081301	0.903078577865636	0.716919089427725	0.913356466681923
GO:0140857	histone H3T45 kinase activity	20/1678	246/18639	0.0813008130081301	0.903078577865636	0.716919089427725	0.913356466681923
GO:0140098	catalytic activity, acting on RNA	32/1678	387/18639	0.082687338501292	0.918479917953267	0.720452745226443	0.916299782393762
GO:0042287	MHC protein binding	3/1678	41/18639	0.0731707317073171	0.812770720079072	0.726868904121855	0.916299782393762
GO:0015294	solute:monoatomic cation symporter activity	9/1678	116/18639	0.0775862068965517	0.861817229049361	0.72739792894423	0.916299782393762
GO:0004679	AMP-activated protein kinase activity	20/1678	248/18639	0.0806451612903226	0.895795686108655	0.730091762215527	0.916299782393762
GO:0051019	mitogen-activated protein kinase binding	2/1678	28/18639	0.0714285714285714	0.793419036267666	0.731589777763304	0.916299782393762
GO:0051959	dynein light intermediate chain binding	2/1678	28/18639	0.0714285714285714	0.793419036267666	0.731589777763304	0.916299782393762
GO:0004065	arylsulfatase activity	1/1678	14/18639	0.0714285714285714	0.793419036267666	0.733194999459869	0.916299782393762
GO:0005313	L-glutamate transmembrane transporter activity	1/1678	14/18639	0.0714285714285714	0.793419036267666	0.733194999459869	0.916299782393762
GO:0005347	ATP transmembrane transporter activity	1/1678	14/18639	0.0714285714285714	0.793419036267666	0.733194999459869	0.916299782393762
GO:0008392	arachidonate epoxygenase activity	1/1678	14/18639	0.0714285714285714	0.793419036267666	0.733194999459869	0.916299782393762
GO:0008474	palmitoyl-(protein) hydrolase activity	1/1678	14/18639	0.0714285714285714	0.793419036267666	0.733194999459869	0.916299782393762
GO:0008494	translation activator activity	1/1678	14/18639	0.0714285714285714	0.793419036267666	0.733194999459869	0.916299782393762
GO:0032454	histone H3K9 demethylase activity	1/1678	14/18639	0.0714285714285714	0.793419036267666	0.733194999459869	0.916299782393762
GO:0034236	protein kinase A catalytic subunit binding	1/1678	14/18639	0.0714285714285714	0.793419036267666	0.733194999459869	0.916299782393762
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/1678	14/18639	0.0714285714285714	0.793419036267666	0.733194999459869	0.916299782393762
GO:0071933	Arp2/3 complex binding	1/1678	14/18639	0.0714285714285714	0.793419036267666	0.733194999459869	0.916299782393762
GO:0098599	palmitoyl hydrolase activity	1/1678	14/18639	0.0714285714285714	0.793419036267666	0.733194999459869	0.916299782393762
GO:0098821	BMP receptor activity	1/1678	14/18639	0.0714285714285714	0.793419036267666	0.733194999459869	0.916299782393762
GO:1990782	protein tyrosine kinase binding	9/1678	117/18639	0.0769230769230769	0.854451269826717	0.736693358238156	0.91969857936497
GO:0019894	kinesin binding	3/1678	42/18639	0.0714285714285714	0.793419036267666	0.741982175827919	0.925323072495008
GO:0015101	organic cation transmembrane transporter activity	6/1678	81/18639	0.0740740740740741	0.822804926499801	0.748251404125183	0.926727051058433
GO:0030971	receptor tyrosine kinase binding	6/1678	81/18639	0.0740740740740741	0.822804926499801	0.748251404125183	0.926727051058433
GO:0004497	monooxygenase activity	8/1678	106/18639	0.0754716981132075	0.838329547754515	0.748793985466384	0.926727051058433
GO:0005416	amino acid:monoatomic cation symporter activity	2/1678	29/18639	0.0689655172413793	0.766059759154987	0.749368036218633	0.926727051058433
GO:0008080	N-acetyltransferase activity	5/1678	69/18639	0.072463768115942	0.80491786288024	0.755744233332666	0.926727051058433
GO:0004089	carbonate dehydratase activity	1/1678	15/18639	0.0666666666666667	0.740524433849821	0.757232518434706	0.926727051058433
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	1/1678	15/18639	0.0666666666666667	0.740524433849821	0.757232518434706	0.926727051058433
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	1/1678	15/18639	0.0666666666666667	0.740524433849821	0.757232518434706	0.926727051058433
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/1678	15/18639	0.0666666666666667	0.740524433849821	0.757232518434706	0.926727051058433
GO:0004953	icosanoid receptor activity	1/1678	15/18639	0.0666666666666667	0.740524433849821	0.757232518434706	0.926727051058433
GO:0008242	omega peptidase activity	1/1678	15/18639	0.0666666666666667	0.740524433849821	0.757232518434706	0.926727051058433
GO:0015116	sulfate transmembrane transporter activity	1/1678	15/18639	0.0666666666666667	0.740524433849821	0.757232518434706	0.926727051058433
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/1678	15/18639	0.0666666666666667	0.740524433849821	0.757232518434706	0.926727051058433
GO:0030553	cGMP binding	1/1678	15/18639	0.0666666666666667	0.740524433849821	0.757232518434706	0.926727051058433
GO:0051371	muscle alpha-actinin binding	1/1678	15/18639	0.0666666666666667	0.740524433849821	0.757232518434706	0.926727051058433
GO:0140161	monocarboxylate:sodium symporter activity	1/1678	15/18639	0.0666666666666667	0.740524433849821	0.757232518434706	0.926727051058433
GO:0141050	histone H3K deacetylase activity	1/1678	15/18639	0.0666666666666667	0.740524433849821	0.757232518434706	0.926727051058433
GO:0141051	histone H4K deacetylase activity	1/1678	15/18639	0.0666666666666667	0.740524433849821	0.757232518434706	0.926727051058433
GO:0019955	cytokine binding	11/1678	144/18639	0.0763888888888889	0.84851758045292	0.75830650463923	0.927080726686264
GO:0005179	hormone activity	10/1678	132/18639	0.0757575757575758	0.841505038465706	0.760431126838954	0.92825879650358
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	18/1678	229/18639	0.0786026200873362	0.873107411089309	0.760842095694721	0.92825879650358
GO:0048019	receptor antagonist activity	2/1678	30/18639	0.0666666666666667	0.740524433849821	0.766122956445457	0.930705864391276
GO:0016790	thiolester hydrolase activity	3/1678	44/18639	0.0681818181818182	0.757354534619135	0.770201774320781	0.930705864391276
GO:0015293	symporter activity	11/1678	146/18639	0.0753424657534247	0.836894051953565	0.773791113400813	0.930705864391276
GO:0004620	phospholipase activity	8/1678	109/18639	0.073394495412844	0.815256257449344	0.775824125260284	0.930705864391276
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/1678	16/18639	0.0625	0.694241656734207	0.779105576535359	0.930705864391276
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	1/1678	16/18639	0.0625	0.694241656734207	0.779105576535359	0.930705864391276
GO:0005149	interleukin-1 receptor binding	1/1678	16/18639	0.0625	0.694241656734207	0.779105576535359	0.930705864391276
GO:0008296	3'-5'-DNA exonuclease activity	1/1678	16/18639	0.0625	0.694241656734207	0.779105576535359	0.930705864391276
GO:0008391	arachidonate monooxygenase activity	1/1678	16/18639	0.0625	0.694241656734207	0.779105576535359	0.930705864391276
GO:0015378	sodium:chloride symporter activity	1/1678	16/18639	0.0625	0.694241656734207	0.779105576535359	0.930705864391276
GO:0015385	sodium:proton antiporter activity	1/1678	16/18639	0.0625	0.694241656734207	0.779105576535359	0.930705864391276
GO:0016722	oxidoreductase activity, acting on metal ions	1/1678	16/18639	0.0625	0.694241656734207	0.779105576535359	0.930705864391276
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/1678	16/18639	0.0625	0.694241656734207	0.779105576535359	0.930705864391276
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1/1678	16/18639	0.0625	0.694241656734207	0.779105576535359	0.930705864391276
GO:0034450	ubiquitin-ubiquitin ligase activity	1/1678	16/18639	0.0625	0.694241656734207	0.779105576535359	0.930705864391276
GO:0055102	lipase inhibitor activity	1/1678	16/18639	0.0625	0.694241656734207	0.779105576535359	0.930705864391276
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/1678	16/18639	0.0625	0.694241656734207	0.779105576535359	0.930705864391276
GO:0140328	floppase activity	1/1678	16/18639	0.0625	0.694241656734207	0.779105576535359	0.930705864391276
GO:0005164	tumor necrosis factor receptor binding	2/1678	31/18639	0.0645161290322581	0.716636548886924	0.781894583311258	0.930705864391276
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/1678	31/18639	0.0645161290322581	0.716636548886924	0.781894583311258	0.930705864391276
GO:0005452	solute:inorganic anion antiporter activity	2/1678	31/18639	0.0645161290322581	0.716636548886924	0.781894583311258	0.930705864391276
GO:0016411	acylglycerol O-acyltransferase activity	2/1678	31/18639	0.0645161290322581	0.716636548886924	0.781894583311258	0.930705864391276
GO:0008009	chemokine activity	3/1678	45/18639	0.0666666666666667	0.740524433849821	0.783337535313233	0.930705864391276
GO:0042605	peptide antigen binding	3/1678	45/18639	0.0666666666666667	0.740524433849821	0.783337535313233	0.930705864391276
GO:0046915	transition metal ion transmembrane transporter activity	3/1678	45/18639	0.0666666666666667	0.740524433849821	0.783337535313233	0.930705864391276
GO:0051539	4 iron, 4 sulfur cluster binding	3/1678	45/18639	0.0666666666666667	0.740524433849821	0.783337535313233	0.930705864391276
GO:0005096	GTPase activator activity	21/1678	271/18639	0.0774907749077491	0.860757183257172	0.795255427053998	0.936140466419348
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	3/1678	46/18639	0.0652173913043478	0.724426076592216	0.795845918000332	0.936140466419348
GO:0030276	clathrin binding	3/1678	46/18639	0.0652173913043478	0.724426076592216	0.795845918000332	0.936140466419348
GO:0051059	NF-kappaB binding	2/1678	32/18639	0.0625	0.694241656734207	0.796724048718329	0.936140466419348
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/1678	17/18639	0.0588235294117647	0.65340391222043	0.799008967104744	0.936140466419348
GO:0004659	prenyltransferase activity	1/1678	17/18639	0.0588235294117647	0.65340391222043	0.799008967104744	0.936140466419348
GO:0008484	sulfuric ester hydrolase activity	1/1678	17/18639	0.0588235294117647	0.65340391222043	0.799008967104744	0.936140466419348
GO:0015278	intracellularly gated calcium channel activity	1/1678	17/18639	0.0588235294117647	0.65340391222043	0.799008967104744	0.936140466419348
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/1678	17/18639	0.0588235294117647	0.65340391222043	0.799008967104744	0.936140466419348
GO:0031489	myosin V binding	1/1678	17/18639	0.0588235294117647	0.65340391222043	0.799008967104744	0.936140466419348
GO:0032183	SUMO binding	1/1678	17/18639	0.0588235294117647	0.65340391222043	0.799008967104744	0.936140466419348
GO:0036041	long-chain fatty acid binding	1/1678	17/18639	0.0588235294117647	0.65340391222043	0.799008967104744	0.936140466419348
GO:0045236	CXCR chemokine receptor binding	1/1678	17/18639	0.0588235294117647	0.65340391222043	0.799008967104744	0.936140466419348
GO:0070403	NAD+ binding	1/1678	17/18639	0.0588235294117647	0.65340391222043	0.799008967104744	0.936140466419348
GO:0140359	ABC-type transporter activity	3/1678	47/18639	0.0638297872340425	0.709012755813659	0.80774479201672	0.944501583536383
GO:0140938	histone H3 methyltransferase activity	3/1678	47/18639	0.0638297872340425	0.709012755813659	0.80774479201672	0.944501583536383
GO:0015026	coreceptor activity	4/1678	61/18639	0.0655737704918033	0.728384689032611	0.811029888916674	0.947404845509982
GO:0004706	JUN kinase kinase kinase activity	1/1678	18/18639	0.0555555555555556	0.617103694874851	0.817119962336097	0.947955476934116
GO:0015172	acidic amino acid transmembrane transporter activity	1/1678	18/18639	0.0555555555555556	0.617103694874851	0.817119962336097	0.947955476934116
GO:0015373	monoatomic anion:sodium symporter activity	1/1678	18/18639	0.0555555555555556	0.617103694874851	0.817119962336097	0.947955476934116
GO:0017128	phospholipid scramblase activity	1/1678	18/18639	0.0555555555555556	0.617103694874851	0.817119962336097	0.947955476934116
GO:0035615	clathrin adaptor activity	1/1678	18/18639	0.0555555555555556	0.617103694874851	0.817119962336097	0.947955476934116
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/1678	18/18639	0.0555555555555556	0.617103694874851	0.817119962336097	0.947955476934116
GO:1990381	ubiquitin-specific protease binding	1/1678	18/18639	0.0555555555555556	0.617103694874851	0.817119962336097	0.947955476934116
GO:0140693	molecular condensate scaffold activity	3/1678	48/18639	0.0625	0.694241656734207	0.819052860996875	0.949265386493925
GO:0015171	amino acid transmembrane transporter activity	7/1678	102/18639	0.0686274509803922	0.762304564257169	0.822826961636724	0.951876088971955
GO:0051427	hormone receptor binding	2/1678	34/18639	0.0588235294117647	0.65340391222043	0.823723423310193	0.951876088971955
GO:0052866	phosphatidylinositol phosphate phosphatase activity	2/1678	34/18639	0.0588235294117647	0.65340391222043	0.823723423310193	0.951876088971955
GO:0017022	myosin binding	5/1678	76/18639	0.0657894736842105	0.730780691299166	0.82557926894965	0.953088090546957
GO:0005229	intracellularly calcium-gated chloride channel activity	1/1678	19/18639	0.0526315789473684	0.584624553039333	0.833599888398071	0.956736120697883
GO:0008381	mechanosensitive monoatomic ion channel activity	1/1678	19/18639	0.0526315789473684	0.584624553039333	0.833599888398071	0.956736120697883
GO:0034987	immunoglobulin receptor binding	1/1678	19/18639	0.0526315789473684	0.584624553039333	0.833599888398071	0.956736120697883
GO:0042800	histone H3K4 methyltransferase activity	1/1678	19/18639	0.0526315789473684	0.584624553039333	0.833599888398071	0.956736120697883
GO:0042834	peptidoglycan binding	1/1678	19/18639	0.0526315789473684	0.584624553039333	0.833599888398071	0.956736120697883
GO:0141147	intracellularly calcium-gated channel activity	1/1678	19/18639	0.0526315789473684	0.584624553039333	0.833599888398071	0.956736120697883
GO:0005343	organic acid:sodium symporter activity	2/1678	35/18639	0.0571428571428571	0.634735229014132	0.835976764957834	0.958532581956507
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	9/1678	130/18639	0.0692307692307692	0.769006142844045	0.8379577032361	0.959872015055125
GO:0000993	RNA polymerase II complex binding	2/1678	36/18639	0.0555555555555556	0.617103694874851	0.847454151002888	0.967366172993117
GO:0016409	palmitoyltransferase activity	2/1678	36/18639	0.0555555555555556	0.617103694874851	0.847454151002888	0.967366172993117
GO:0044390	ubiquitin-like protein conjugating enzyme binding	2/1678	36/18639	0.0555555555555556	0.617103694874851	0.847454151002888	0.967366172993117
GO:0015464	acetylcholine receptor activity	1/1678	20/18639	0.05	0.555393325387366	0.848595559035452	0.967366172993117
GO:0140939	histone H4 methyltransferase activity	1/1678	20/18639	0.05	0.555393325387366	0.848595559035452	0.967366172993117
GO:0031267	small GTPase binding	21/1678	283/18639	0.0742049469964664	0.824258645451214	0.852096670083427	0.969904494404416
GO:0030695	GTPase regulator activity	38/1678	489/18639	0.0777096114519427	0.863187990377092	0.852464746140376	0.969904494404416
GO:0060589	nucleoside-triphosphatase regulator activity	38/1678	490/18639	0.0775510204081633	0.861426382233465	0.855667931756363	0.971666150189515
GO:0019213	deacetylase activity	2/1678	37/18639	0.0540540540540541	0.60042521663499	0.858195886497235	0.971666150189515
GO:0023023	MHC protein complex binding	2/1678	37/18639	0.0540540540540541	0.60042521663499	0.858195886497235	0.971666150189515
GO:0016410	N-acyltransferase activity	6/1678	94/18639	0.0638297872340425	0.709012755813659	0.860481619486246	0.971666150189515
GO:0008373	sialyltransferase activity	1/1678	21/18639	0.0476190476190476	0.528946024178444	0.862240580354455	0.971666150189515
GO:0009931	calcium-dependent protein serine/threonine kinase activity	1/1678	21/18639	0.0476190476190476	0.528946024178444	0.862240580354455	0.971666150189515
GO:0009975	cyclase activity	1/1678	21/18639	0.0476190476190476	0.528946024178444	0.862240580354455	0.971666150189515
GO:0010314	phosphatidylinositol-5-phosphate binding	1/1678	21/18639	0.0476190476190476	0.528946024178444	0.862240580354455	0.971666150189515
GO:0036122	BMP binding	1/1678	21/18639	0.0476190476190476	0.528946024178444	0.862240580354455	0.971666150189515
GO:0140312	cargo adaptor activity	1/1678	21/18639	0.0476190476190476	0.528946024178444	0.862240580354455	0.971666150189515
GO:0042054	histone methyltransferase activity	4/1678	67/18639	0.0597014925373134	0.66315620941775	0.864387876308023	0.973157370752884
GO:0005544	calcium-dependent phospholipid binding	3/1678	53/18639	0.0566037735849057	0.628747160815886	0.867420478705955	0.975056822934637
GO:0015291	secondary active transmembrane transporter activity	21/1678	287/18639	0.0731707317073171	0.812770720079072	0.868137469276545	0.975056822934637
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	8/1678	122/18639	0.0655737704918033	0.728384689032611	0.868551886305875	0.975056822934637
GO:0004407	histone deacetylase activity	1/1678	22/18639	0.0454545454545455	0.504903023079424	0.874656538360966	0.975419614546082
GO:0008093	cytoskeletal anchor activity	1/1678	22/18639	0.0454545454545455	0.504903023079424	0.874656538360966	0.975419614546082
GO:0008649	rRNA methyltransferase activity	1/1678	22/18639	0.0454545454545455	0.504903023079424	0.874656538360966	0.975419614546082
GO:0008970	phospholipase A1 activity	1/1678	22/18639	0.0454545454545455	0.504903023079424	0.874656538360966	0.975419614546082
GO:0015377	chloride:monoatomic cation symporter activity	1/1678	22/18639	0.0454545454545455	0.504903023079424	0.874656538360966	0.975419614546082
GO:0016881	acid-amino acid ligase activity	1/1678	22/18639	0.0454545454545455	0.504903023079424	0.874656538360966	0.975419614546082
GO:0033558	protein lysine deacetylase activity	1/1678	22/18639	0.0454545454545455	0.504903023079424	0.874656538360966	0.975419614546082
GO:0030165	PDZ domain binding	5/1678	83/18639	0.0602409638554217	0.669148584804055	0.878291752768223	0.978465954928248
GO:0002039	p53 binding	4/1678	69/18639	0.0579710144927536	0.643934290304192	0.879045197441889	0.978465954928248
GO:0008374	O-acyltransferase activity	3/1678	55/18639	0.0545454545454545	0.605883627695308	0.883329267171617	0.97926321711265
GO:0008170	N-methyltransferase activity	6/1678	98/18639	0.0612244897959184	0.680073459657999	0.885318364919488	0.97926321711265
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/1678	23/18639	0.0434782608695652	0.482950717728144	0.885954079781727	0.97926321711265
GO:0016493	C-C chemokine receptor activity	1/1678	23/18639	0.0434782608695652	0.482950717728144	0.885954079781727	0.97926321711265
GO:0016849	phosphorus-oxygen lyase activity	1/1678	23/18639	0.0434782608695652	0.482950717728144	0.885954079781727	0.97926321711265
GO:0140102	catalytic activity, acting on a rRNA	1/1678	23/18639	0.0434782608695652	0.482950717728144	0.885954079781727	0.97926321711265
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	2/1678	40/18639	0.05	0.555393325387366	0.886394901857259	0.97926321711265
GO:0071855	neuropeptide receptor binding	2/1678	40/18639	0.05	0.555393325387366	0.886394901857259	0.97926321711265
GO:0140767	enzyme-substrate adaptor activity	9/1678	139/18639	0.0647482014388489	0.719214378199467	0.888159222508376	0.980295366151768
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	19/1678	268/18639	0.0708955223880597	0.787497998683579	0.889889373020797	0.98128790806495
GO:0004812	aminoacyl-tRNA ligase activity	2/1678	41/18639	0.0487804878048781	0.541847146719381	0.894575722253946	0.981991233611245
GO:0016875	ligase activity, forming carbon-oxygen bonds	2/1678	41/18639	0.0487804878048781	0.541847146719381	0.894575722253946	0.981991233611245
GO:0140828	metal cation:monoatomic cation antiporter activity	2/1678	41/18639	0.0487804878048781	0.541847146719381	0.894575722253946	0.981991233611245
GO:0005315	phosphate transmembrane transporter activity	1/1678	24/18639	0.0416666666666667	0.462827771156138	0.896233895753271	0.981991233611245
GO:0019957	C-C chemokine binding	1/1678	24/18639	0.0416666666666667	0.462827771156138	0.896233895753271	0.981991233611245
GO:0030552	cAMP binding	1/1678	24/18639	0.0416666666666667	0.462827771156138	0.896233895753271	0.981991233611245
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	5/1678	86/18639	0.0581395348837209	0.645806192310891	0.896347628986386	0.981991233611245
GO:0043175	RNA polymerase core enzyme binding	2/1678	42/18639	0.0476190476190476	0.528946024178444	0.902205399575248	0.987492656995707
GO:0003707	nuclear steroid receptor activity	1/1678	25/18639	0.04	0.444314660309893	0.905587617103043	0.989360754670392
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/1678	25/18639	0.04	0.444314660309893	0.905587617103043	0.989360754670392
GO:0016651	oxidoreductase activity, acting on NAD(P)H	5/1678	88/18639	0.0568181818181818	0.631128778849279	0.90705456365642	0.989505482165522
GO:0016298	lipase activity	8/1678	130/18639	0.0615384615384615	0.683561015861373	0.908140406403235	0.989505482165522
GO:0001637	G protein-coupled chemoattractant receptor activity	1/1678	26/18639	0.0384615384615385	0.427225634913358	0.914098629163916	0.989505482165522
GO:0004435	phosphatidylinositol phospholipase C activity	1/1678	26/18639	0.0384615384615385	0.427225634913358	0.914098629163916	0.989505482165522
GO:0004950	chemokine receptor activity	1/1678	26/18639	0.0384615384615385	0.427225634913358	0.914098629163916	0.989505482165522
GO:0005160	transforming growth factor beta receptor binding	1/1678	26/18639	0.0384615384615385	0.427225634913358	0.914098629163916	0.989505482165522
GO:0030247	polysaccharide binding	1/1678	26/18639	0.0384615384615385	0.427225634913358	0.914098629163916	0.989505482165522
GO:0043548	phosphatidylinositol 3-kinase binding	1/1678	26/18639	0.0384615384615385	0.427225634913358	0.914098629163916	0.989505482165522
GO:0051139	metal cation:proton antiporter activity	1/1678	26/18639	0.0384615384615385	0.427225634913358	0.914098629163916	0.989505482165522
GO:0052742	phosphatidylinositol kinase activity	1/1678	26/18639	0.0384615384615385	0.427225634913358	0.914098629163916	0.989505482165522
GO:0008234	cysteine-type peptidase activity	12/1678	187/18639	0.0641711229946524	0.712804267876833	0.920401685835759	0.992717095268589
GO:0001217	DNA-binding transcription repressor activity	19/1678	278/18639	0.0683453237410072	0.759170732543882	0.920484087424953	0.992717095268589
GO:0004683	calcium/calmodulin-dependent protein kinase activity	1/1678	27/18639	0.037037037037037	0.411402463249901	0.921842813350396	0.992717095268589
GO:0005044	scavenger receptor activity	1/1678	27/18639	0.037037037037037	0.411402463249901	0.921842813350396	0.992717095268589
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	1/1678	27/18639	0.037037037037037	0.411402463249901	0.921842813350396	0.992717095268589
GO:0140303	intramembrane lipid transporter activity	2/1678	45/18639	0.0444444444444444	0.493682955899881	0.92210893607929	0.992717095268589
GO:0000149	SNARE binding	6/1678	106/18639	0.0566037735849057	0.628747160815886	0.923891102347002	0.993729865092722
GO:0015297	antiporter activity	8/1678	135/18639	0.0592592592592593	0.658243941199841	0.927336418815303	0.996383443480083
GO:0008509	monoatomic anion transmembrane transporter activity	9/1678	149/18639	0.0604026845637584	0.670944956843798	0.928102864094678	0.996383443480083
GO:0141052	histone H3 demethylase activity	1/1678	28/18639	0.0357142857142857	0.396709518133833	0.928889222075844	0.996383443480083
GO:0015370	solute:sodium symporter activity	4/1678	79/18639	0.0506329113924051	0.562423620645434	0.933406597784895	0.999999999942464
GO:0004181	metallocarboxypeptidase activity	1/1678	29/18639	0.0344827586206897	0.383029879577494	0.935300692999316	0.999999999942464
GO:0099604	ligand-gated calcium channel activity	1/1678	29/18639	0.0344827586206897	0.383029879577494	0.935300692999316	0.999999999942464
GO:0008188	neuropeptide receptor activity	2/1678	48/18639	0.0416666666666667	0.462827771156138	0.938148406209054	0.999999999942464
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/1678	30/18639	0.0333333333333333	0.370262216924911	0.941134408052897	0.999999999942464
GO:0032452	histone demethylase activity	1/1678	30/18639	0.0333333333333333	0.370262216924911	0.941134408052897	0.999999999942464
GO:0070566	adenylyltransferase activity	1/1678	30/18639	0.0333333333333333	0.370262216924911	0.941134408052897	0.999999999942464
GO:0019783	ubiquitin-like protein peptidase activity	7/1678	127/18639	0.0551181102362205	0.612244610663238	0.946347220748149	0.999999999942464
GO:0005184	neuropeptide hormone activity	1/1678	31/18639	0.032258064516129	0.358318274443462	0.946442402210952	0.999999999942464
GO:0140457	protein demethylase activity	1/1678	31/18639	0.032258064516129	0.358318274443462	0.946442402210952	0.999999999942464
GO:0032813	tumor necrosis factor receptor superfamily binding	2/1678	50/18639	0.04	0.444314660309893	0.947042135319895	0.999999999942464
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	3/1678	67/18639	0.0447761194029851	0.497367157063313	0.947650744376608	0.999999999942464
GO:0140223	general transcription initiation factor activity	3/1678	68/18639	0.0441176470588235	0.490052934165323	0.951147056480242	0.999999999942464
GO:0160041	neuropeptide activity	1/1678	32/18639	0.03125	0.347120828367104	0.951272026517165	0.999999999942464
GO:0101005	deubiquitinase activity	6/1678	115/18639	0.0521739130434783	0.579540861273773	0.953235266194977	0.999999999942464
GO:0016798	hydrolase activity, acting on glycosyl bonds	7/1678	130/18639	0.0538461538461538	0.598115888878702	0.954140086790574	0.999999999942464
GO:0016279	protein-lysine N-methyltransferase activity	3/1678	69/18639	0.0434782608695652	0.482950717728144	0.954424413709258	0.999999999942464
GO:0140030	modification-dependent protein binding	10/1678	173/18639	0.0578034682080925	0.642073208540307	0.95503234356679	0.999999999942464
GO:0019239	deaminase activity	1/1678	33/18639	0.0303030303030303	0.336602015386282	0.955666369479717	0.999999999942464
GO:0030296	protein tyrosine kinase activator activity	1/1678	33/18639	0.0303030303030303	0.336602015386282	0.955666369479717	0.999999999942464
GO:0140311	protein sequestering activity	1/1678	33/18639	0.0303030303030303	0.336602015386282	0.955666369479717	0.999999999942464
GO:0016278	lysine N-methyltransferase activity	3/1678	70/18639	0.0428571428571429	0.476051421760599	0.957495163013233	0.999999999942464
GO:0016251	RNA polymerase II general transcription initiation factor activity	2/1678	53/18639	0.0377358490566038	0.419164773877257	0.958131225172055	0.999999999942464
GO:0034212	protein N-acetyltransferase activity	2/1678	53/18639	0.0377358490566038	0.419164773877257	0.958131225172055	0.999999999942464
GO:0015020	glucuronosyltransferase activity	1/1678	34/18639	0.0294117647058824	0.326701956110215	0.959664640575763	0.999999999942464
GO:0005253	monoatomic anion channel activity	5/1678	103/18639	0.0485436893203883	0.539216820764433	0.960775601927023	0.999999999942464
GO:0042379	chemokine receptor binding	3/1678	72/18639	0.0416666666666667	0.462827771156138	0.963063417924726	0.999999999942464
GO:0005125	cytokine activity	14/1678	234/18639	0.0598290598290598	0.664573209865224	0.965318592433446	0.999999999942464
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/1678	36/18639	0.0277777777777778	0.308551847437426	0.96661247264948	0.999999999942464
GO:0045505	dynein intermediate chain binding	1/1678	36/18639	0.0277777777777778	0.308551847437426	0.96661247264948	0.999999999942464
GO:0008528	G protein-coupled peptide receptor activity	6/1678	122/18639	0.0491803278688525	0.546288516774458	0.968516385178867	0.999999999942464
GO:0030280	structural constituent of skin epidermis	1/1678	37/18639	0.027027027027027	0.300212608317495	0.969624044487042	0.999999999942464
GO:0001216	DNA-binding transcription activator activity	33/1678	491/18639	0.0672097759674134	0.746557219461632	0.973198983895792	0.999999999942464
GO:0031593	polyubiquitin modification-dependent protein binding	2/1678	59/18639	0.0338983050847458	0.376537847720248	0.974005141259228	0.999999999942464
GO:0001653	peptide receptor activity	6/1678	128/18639	0.046875	0.520681242550656	0.977808566362712	0.999999999942464
GO:0001727	lipid kinase activity	1/1678	41/18639	0.024390243902439	0.270923573359691	0.9791891622191	0.999999999942464
GO:0160215	deacylase activity	2/1678	65/18639	0.0307692307692308	0.341780507930687	0.983985411825818	0.999999999942464
GO:0004180	carboxypeptidase activity	1/1678	46/18639	0.0217391304347826	0.241475358864072	0.987030089530347	0.999999999942464
GO:0061733	protein-lysine-acetyltransferase activity	1/1678	47/18639	0.0212765957446809	0.23633758527122	0.988200611219589	0.999999999942464
GO:0099095	ligand-gated monoatomic anion channel activity	1/1678	47/18639	0.0212765957446809	0.23633758527122	0.988200611219589	0.999999999942464
GO:0005085	guanyl-nucleotide exchange factor activity	12/1678	230/18639	0.0521739130434783	0.579540861273773	0.988585097725623	0.999999999942464
GO:0004843	cysteine-type deubiquitinase activity	4/1678	108/18639	0.037037037037037	0.411402463249901	0.99015488053889	0.999999999942464
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	30/1678	484/18639	0.0619834710743802	0.688504122381032	0.9910358335658	0.999999999942464
GO:0048020	CCR chemokine receptor binding	1/1678	50/18639	0.02	0.222157330154946	0.991115904778499	0.999999999942464
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/1678	53/18639	0.0188679245283019	0.209582386938629	0.993311233491438	0.999999999942464
GO:0004896	cytokine receptor activity	3/1678	96/18639	0.03125	0.347120828367104	0.99366503047957	0.999999999942464
GO:0015103	inorganic anion transmembrane transporter activity	7/1678	165/18639	0.0424242424242424	0.471242821540795	0.993783414192617	0.999999999942464
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/1678	56/18639	0.0178571428571429	0.198354759066916	0.994964321473976	0.999999999942464
GO:0015108	chloride transmembrane transporter activity	4/1678	121/18639	0.0330578512396694	0.367202198603217	0.996081142278739	0.999999999942464
GO:0001540	amyloid-beta binding	2/1678	83/18639	0.0240963855421687	0.267659433921622	0.996388156163792	0.999999999942464
GO:0005254	chloride channel activity	2/1678	83/18639	0.0240963855421687	0.267659433921622	0.996388156163792	0.999999999942464
GO:0022824	transmitter-gated monoatomic ion channel activity	1/1678	63/18639	0.0158730158730159	0.176315341392815	0.997403999883634	0.999999999942464
GO:0022835	transmitter-gated channel activity	1/1678	63/18639	0.0158730158730159	0.176315341392815	0.997403999883634	0.999999999942464
GO:0015081	sodium ion transmembrane transporter activity	6/1678	164/18639	0.0365853658536585	0.406385360039536	0.997701020597105	0.999999999942464
GO:0015085	calcium ion transmembrane transporter activity	5/1678	147/18639	0.0340136054421769	0.377818588698888	0.997776447910821	0.999999999942464
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	2/1678	91/18639	0.021978021978022	0.244128934236205	0.998161943918582	0.999999999942464
GO:0098960	postsynaptic neurotransmitter receptor activity	1/1678	69/18639	0.0144927536231884	0.160983572576048	0.998529149621619	0.999999999942464
GO:0030527	structural constituent of chromatin	2/1678	98/18639	0.0204081632653061	0.226691153219333	0.998987752890222	0.999999999942464
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/1678	73/18639	0.0136986301369863	0.152162554900648	0.998992995916472	0.999999999942464
GO:0003823	antigen binding	5/1678	174/18639	0.028735632183908	0.319191566314578	0.999678011652907	0.999999999942464
GO:0140375	immune receptor activity	4/1678	156/18639	0.0256410256410256	0.284817089942239	0.999713199052771	0.999999999942464
GO:0061630	ubiquitin protein ligase activity	15/1678	353/18639	0.0424929178470255	0.472005658969433	0.999818083820023	0.999999999942464
GO:0019787	ubiquitin-like protein transferase activity	23/1678	479/18639	0.0480167014613779	0.533363109975341	0.999847860332139	0.999999999942464
GO:0004842	ubiquitin-protein transferase activity	21/1678	449/18639	0.0467706013363029	0.519521596130721	0.999848215966825	0.999999999942464
GO:0061659	ubiquitin-like protein ligase activity	16/1678	372/18639	0.043010752688172	0.477757699257949	0.999848353807914	0.999999999942464
GO:0005126	cytokine receptor binding	10/1678	275/18639	0.0363636363636364	0.403922418463539	0.99985515163398	0.999999999942464
GO:0030594	neurotransmitter receptor activity	1/1678	97/18639	0.0103092783505155	0.114514087708735	0.999896479549113	0.999999999942464
GO:0016755	aminoacyltransferase activity	23/1678	496/18639	0.0463709677419355	0.515082519512476	0.999936323870137	0.999999999942464
GO:0005262	calcium channel activity	2/1678	131/18639	0.0152671755725191	0.169585748209883	0.999942316927724	0.999999999942464
GO:0099094	ligand-gated monoatomic cation channel activity	2/1678	136/18639	0.0147058823529412	0.163350978055108	0.999962855131853	0.999999999942464
GO:0015276	ligand-gated monoatomic ion channel activity	3/1678	186/18639	0.0161290322580645	0.179159137221731	0.99999581326261	0.999999999942464
GO:0022834	ligand-gated channel activity	3/1678	188/18639	0.0159574468085106	0.177253188953415	0.999996468347623	0.999999999942464
GO:0005244	voltage-gated monoatomic ion channel activity	2/1678	173/18639	0.0115606936416185	0.128414641708061	0.999998620564779	0.999999999942464
GO:0022832	voltage-gated channel activity	2/1678	175/18639	0.0114285714285714	0.126947045802827	0.999998847288409	0.999999999942464
GO:0045182	translation regulator activity	10/1678	356/18639	0.0280898876404494	0.312018722127734	0.999999397546538	0.999999999942464
GO:0046873	metal ion transmembrane transporter activity	15/1678	450/18639	0.0333333333333333	0.370262216924911	0.999999528279305	0.999999999942464
GO:0022836	gated channel activity	6/1678	318/18639	0.0188679245283019	0.209582386938629	0.999999977109986	0.999999999942464
GO:0030371	translation repressor activity	5/1678	329/18639	0.0151975683890578	0.168812560908014	0.999999998609292	0.999999999942464
GO:0005216	monoatomic ion channel activity	9/1678	448/18639	0.0200892857142857	0.223149103950281	0.999999999868641	0.999999999942464
GO:0005261	monoatomic cation channel activity	4/1678	341/18639	0.0117302052785924	0.130297554343077	0.999999999942464	0.999999999942464