ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	102/2115	175/18639	0.582857142857143	5.13658358662614	2.8102901888383e-51	3.51848331642555e-48
GO:0045296	cadherin binding	105/2115	334/18639	0.31437125748503	2.77048031596382	2.33739567461902e-23	1.46320969231151e-20
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	31/2115	68/18639	0.455882352941176	4.01758448060075	1.3014807581778e-12	5.43151303079533e-10
GO:0009055	electron transfer activity	40/2115	116/18639	0.344827586206897	3.03888481291269	3.95779645669846e-11	1.23879029094662e-08
GO:0022853	active monoatomic ion transmembrane transporter activity	39/2115	118/18639	0.330508474576271	2.91269383339344	2.93495490739291e-10	7.34912708811186e-08
GO:0003779	actin binding	94/2115	443/18639	0.212189616252822	1.86997742663657	1.12296582522142e-09	2.34325535529536e-07
GO:0004601	peroxidase activity	24/2115	57/18639	0.421052631578947	3.71063829787234	3.2536348832515e-09	5.81935839118697e-07
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	24/2115	59/18639	0.406779661016949	3.58485394879192	7.45767294219346e-09	1.16712581545328e-06
GO:0003743	translation initiation factor activity	22/2115	51/18639	0.431372549019608	3.80158531497705	8.51131797293613e-09	1.18401890023512e-06
GO:0008135	translation factor activity, RNA binding	29/2115	83/18639	0.349397590361446	3.07915918995129	1.32418713657014e-08	1.65788229498581e-06
GO:0180051	translation factor activity	29/2115	84/18639	0.345238095238095	3.04250253292806	1.80463767951554e-08	2.05400579523042e-06
GO:0031720	haptoglobin binding	9/2115	10/18639	0.9	7.93148936170213	2.75949188320849e-08	2.87906986481419e-06
GO:0051015	actin filament binding	52/2115	209/18639	0.248803827751196	2.1926499032882	3.01040799008983e-08	2.8992544643019e-06
GO:0016209	antioxidant activity	29/2115	86/18639	0.337209302325581	2.97174666006927	3.29092318239362e-08	2.94302558882629e-06
GO:0015399	primary active transmembrane transporter activity	43/2115	166/18639	0.259036144578313	2.28282491668803	1.3688805869111e-07	1.14255899654179e-05
GO:0019843	rRNA binding	23/2115	65/18639	0.353846153846154	3.11836333878887	3.17963538227241e-07	2.48806468662816e-05
GO:0048027	mRNA 5'-UTR binding	13/2115	24/18639	0.541666666666667	4.77358156028369	3.70982787382828e-07	2.73217911649e-05
GO:0015078	proton transmembrane transporter activity	45/2115	185/18639	0.243243243243243	2.14364577343301	4.99027740183616e-07	3.47101517061049e-05
GO:0004129	cytochrome-c oxidase activity	10/2115	15/18639	0.666666666666667	5.87517730496454	6.07178825232769e-07	4.00098889048119e-05
GO:0008137	NADH dehydrogenase (ubiquinone) activity	17/2115	41/18639	0.414634146341463	3.65407368967307	8.34313698626589e-07	5.22280375340245e-05
GO:0016675	oxidoreductase activity, acting on a heme group of donors	10/2115	16/18639	0.625	5.50797872340426	1.45359808785724e-06	8.66621336189176e-05
GO:0031625	ubiquitin protein ligase binding	62/2115	302/18639	0.205298013245033	1.80924334225729	2.39310747862266e-06	0.000136189571056162
GO:0044389	ubiquitin-like protein ligase binding	65/2115	322/18639	0.201863354037267	1.77897449451566	2.52025076585569e-06	0.000137189302558753
GO:0003954	NADH dehydrogenase activity	17/2115	44/18639	0.386363636363636	3.40493230174081	2.7045863355855e-06	0.00014108925383971
GO:0140662	ATP-dependent protein folding chaperone	16/2115	40/18639	0.4	3.52510638297872	3.1008811289066e-06	0.000155292126935643
GO:1990948	ubiquitin ligase inhibitor activity	8/2115	11/18639	0.727272727272727	6.40928433268859	3.26322164896984e-06	0.000157136673250394
GO:0005344	oxygen carrier activity	9/2115	14/18639	0.642857142857143	5.66534954407295	3.60123625108616e-06	0.000166990658754069
GO:0055105	ubiquitin-protein transferase inhibitor activity	9/2115	15/18639	0.6	5.28765957446809	8.09232238986626e-06	0.000361842415432591
GO:0019825	oxygen binding	14/2115	34/18639	0.411764705882353	3.6287859824781	8.59393276338984e-06	0.000371020821371175
GO:0003697	single-stranded DNA binding	31/2115	121/18639	0.256198347107438	2.25781607174257	9.32618764307849e-06	0.000376657642875299
GO:0051082	unfolded protein binding	31/2115	121/18639	0.256198347107438	2.25781607174257	9.32618764307849e-06	0.000376657642875299
GO:0016651	oxidoreductase activity, acting on NAD(P)H	25/2115	88/18639	0.284090909090909	2.50362669245648	9.74709254927178e-06	0.000381354995990258
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	19/2115	58/18639	0.327586206896552	2.88694057226706	1.21286347905745e-05	0.000460153053266644
GO:0003688	DNA replication origin binding	9/2115	16/18639	0.5625	4.95718085106383	1.66278250638779e-05	0.000612295205293385
GO:0031994	insulin-like growth factor I binding	8/2115	13/18639	0.615384615384615	5.42324058919804	2.06152329969223e-05	0.000737436334632764
GO:0030515	snoRNA binding	13/2115	32/18639	0.40625	3.58018617021277	2.14723366509561e-05	0.000746760152416585
GO:0022804	active transmembrane transporter activity	81/2115	457/18639	0.177242888402626	1.5620000931142	2.88935809403447e-05	0.000977696306413825
GO:0043021	ribonucleoprotein complex binding	39/2115	177/18639	0.220338983050847	1.94179588892896	3.31894882986244e-05	0.00109350629868099
GO:0016860	intramolecular oxidoreductase activity	17/2115	53/18639	0.320754716981132	2.82673625050181	4.68598553002801e-05	0.00150432150861412
GO:0050786	RAGE receptor binding	7/2115	11/18639	0.636363636363636	5.60812379110251	5.227563393928e-05	0.00163622734229947
GO:0017124	SH3 domain binding	28/2115	115/18639	0.243478260869565	2.14571692876966	6.64570333977427e-05	0.00202937087351156
GO:0015036	disulfide oxidoreductase activity	14/2115	40/18639	0.35	3.08446808510638	7.41544760200608e-05	0.00221050961850276
GO:0055106	ubiquitin-protein transferase regulator activity	13/2115	36/18639	0.361111111111111	3.18238770685579	9.23005809941901e-05	0.00268744947452851
GO:0005520	insulin-like growth factor binding	9/2115	19/18639	0.473684210526316	4.17446808510638	9.76252115147766e-05	0.00277788101855682
GO:0019838	growth factor binding	31/2115	136/18639	0.227941176470588	2.00879224030038	0.000105775074821306	0.00294289763725056
GO:0017116	single-stranded DNA helicase activity	17/2115	58/18639	0.293103448275862	2.58305209097579	0.00016478176864344	0.00445035920381367
GO:0004857	enzyme inhibitor activity	72/2115	416/18639	0.173076923076923	1.52528641571195	0.000167066200143165	0.00445035920381367
GO:0044183	protein folding chaperone	20/2115	75/18639	0.266666666666667	2.35007092198582	0.000191465903907888	0.00499406899359741
GO:0015035	protein-disulfide reductase activity	12/2115	34/18639	0.352941176470588	3.11038798498123	0.000220034778960302	0.00562211312772036
GO:0016853	isomerase activity	37/2115	180/18639	0.205555555555556	1.81151300236407	0.000235516279273473	0.00589732763300777
GO:0070182	DNA polymerase binding	9/2115	21/18639	0.428571428571429	3.77689969604863	0.000251346743298585	0.00617031612960449
GO:0043022	ribosome binding	26/2115	112/18639	0.232142857142857	2.04582066869301	0.000271069869234556	0.00652652839003199
GO:0008017	microtubule binding	51/2115	276/18639	0.184782608695652	1.62844588344126	0.000299073691277171	0.00706491059394373
GO:0000287	magnesium ion binding	44/2115	230/18639	0.191304347826087	1.6859204440333	0.000349111992783839	0.00809422620306233
GO:0098641	cadherin binding involved in cell-cell adhesion	8/2115	18/18639	0.444444444444444	3.91678486997636	0.000414991954902221	0.00944672595522874
GO:0003678	DNA helicase activity	19/2115	74/18639	0.256756756756757	2.2627372052904	0.000462756668164084	0.0103459169382399
GO:0004602	glutathione peroxidase activity	9/2115	23/18639	0.391304347826087	3.44847363552266	0.000565782186768727	0.0124273561023587
GO:0005536	D-glucose binding	6/2115	11/18639	0.545454545454545	4.80696324951644	0.000589762154304522	0.0127307278825735
GO:0005200	structural constituent of cytoskeleton	25/2115	112/18639	0.223214285714286	1.96713525835866	0.000657640113383457	0.0131986053706062
GO:0098631	cell adhesion mediator activity	19/2115	76/18639	0.25	2.2031914893617	0.000662239346667853	0.0131986053706062
GO:0015631	tubulin binding	65/2115	385/18639	0.168831168831169	1.48786957723128	0.000670966633376601	0.0131986053706062
GO:0000774	adenyl-nucleotide exchange factor activity	7/2115	15/18639	0.466666666666667	4.11262411347518	0.000674689092427155	0.0131986053706062
GO:0031386	protein tag activity	7/2115	15/18639	0.466666666666667	4.11262411347518	0.000674689092427155	0.0131986053706062
GO:0141047	molecular tag activity	7/2115	15/18639	0.466666666666667	4.11262411347518	0.000674689092427155	0.0131986053706062
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	15/2115	54/18639	0.277777777777778	2.44799054373522	0.000737720147853572	0.0142096250017334
GO:0016887	ATP hydrolysis activity	69/2115	417/18639	0.165467625899281	1.45822746058472	0.000821016356950253	0.0155744314985109
GO:0098632	cell-cell adhesion mediator activity	15/2115	55/18639	0.272727272727273	2.40348162475822	0.000909428699249512	0.0168459785363172
GO:0000217	DNA secondary structure binding	12/2115	39/18639	0.307692307692308	2.71162029459902	0.000914957300694546	0.0168459785363172
GO:0043024	ribosomal small subunit binding	8/2115	20/18639	0.4	3.52510638297872	0.000969902897128149	0.0174119986883316
GO:0051087	protein-folding chaperone binding	28/2115	134/18639	0.208955223880597	1.8414734836456	0.000980367930873685	0.0174119986883316
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	16/2115	61/18639	0.262295081967213	2.31154516916638	0.000987421650855865	0.0174119986883316
GO:0097371	MDM2/MDM4 family protein binding	6/2115	12/18639	0.5	4.4063829787234	0.00106639624437932	0.0185434458050404
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	12/2115	40/18639	0.3	2.64382978723404	0.00117378069905812	0.0201311429482296
GO:1990841	promoter-specific chromatin binding	17/2115	68/18639	0.25	2.2031914893617	0.00124640185632625	0.0210877719475738
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	13/2115	46/18639	0.282608695652174	2.49056429232192	0.00137329786366818	0.0229249190041675
GO:0019903	protein phosphatase binding	29/2115	144/18639	0.201388888888889	1.77479314420804	0.00147493657787015	0.0242976394143872
GO:0004029	aldehyde dehydrogenase (NAD+) activity	7/2115	17/18639	0.411764705882353	3.6287859824781	0.00166097258501346	0.0270069828108683
GO:0140104	molecular carrier activity	44/2115	249/18639	0.176706827309237	1.55727591215928	0.00189106773497053	0.030354061592091
GO:0140517	protein-RNA adaptor activity	8/2115	22/18639	0.363636363636364	3.20464216634429	0.00200031017728941	0.0317011182527384
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	7/2115	18/18639	0.388888888888889	3.42718676122931	0.0024538693496297	0.0384030553217049
GO:0019842	vitamin binding	29/2115	150/18639	0.193333333333333	1.70380141843972	0.00279988402329926	0.043186227615099
GO:0097718	disordered domain specific binding	9/2115	28/18639	0.321428571428571	2.83267477203647	0.00282849094603684	0.043186227615099
GO:0047429	nucleoside triphosphate diphosphatase activity	5/2115	10/18639	0.5	4.4063829787234	0.00288499864631144	0.0435182928335171
GO:0043236	laminin binding	9/2115	29/18639	0.310344827586207	2.73499633162142	0.00369426392059241	0.0550621241497822
GO:1901682	sulfur compound transmembrane transporter activity	15/2115	63/18639	0.238095238095238	2.09827760891591	0.0039087223103672	0.0575731803832909
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	6/2115	15/18639	0.4	3.52510638297872	0.00427534746125254	0.0622411049010253
GO:0061650	ubiquitin-like protein conjugating enzyme activity	11/2115	41/18639	0.268292682926829	2.36440062272963	0.00488294309778463	0.0702694799819121
GO:0140097	catalytic activity, acting on DNA	54/2115	336/18639	0.160714285714286	1.41633738601824	0.00527622389125601	0.0750662762710514
GO:0045309	protein phosphorylated amino acid binding	14/2115	59/18639	0.23728813559322	2.09116480346195	0.00538780666870915	0.0757925162834141
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	6/2115	16/18639	0.375	3.30478723404255	0.00619109723448551	0.0861250415286206
GO:0008094	ATP-dependent activity, acting on DNA	36/2115	210/18639	0.171428571428571	1.51075987841945	0.00755726390011127	0.103157855120582
GO:0048306	calcium-dependent protein binding	17/2115	80/18639	0.2125	1.87271276595745	0.00758028967339741	0.103157855120582
GO:0005178	integrin binding	29/2115	161/18639	0.180124223602484	1.58739262587551	0.00787496640329377	0.105783285316032
GO:0003684	damaged DNA binding	16/2115	74/18639	0.216216216216216	1.90546290971823	0.00794219554289695	0.105783285316032
GO:0140297	DNA-binding transcription factor binding	73/2115	488/18639	0.149590163934426	1.3183031042902	0.00824774059583059	0.106446743516701
GO:0015101	organic cation transmembrane transporter activity	17/2115	81/18639	0.209876543209877	1.84959285526661	0.00860513217624147	0.106446743516701
GO:0019205	nucleobase-containing compound kinase activity	11/2115	44/18639	0.25	2.2031914893617	0.00862935082497542	0.106446743516701
GO:0005092	GDP-dissociation inhibitor activity	6/2115	17/18639	0.352941176470588	3.11038798498123	0.0086620743160157	0.106446743516701
GO:1990226	histone methyltransferase binding	6/2115	17/18639	0.352941176470588	3.11038798498123	0.0086620743160157	0.106446743516701
GO:0019212	phosphatase inhibitor activity	13/2115	56/18639	0.232142857142857	2.04582066869301	0.008707000133739	0.106446743516701
GO:0048020	CCR chemokine receptor binding	12/2115	50/18639	0.24	2.11506382978723	0.00875660694617299	0.106446743516701
GO:0061133	endopeptidase activator activity	7/2115	22/18639	0.318181818181818	2.80406189555126	0.0087572001455433	0.106446743516701
GO:0070034	telomerase RNA binding	7/2115	22/18639	0.318181818181818	2.80406189555126	0.0087572001455433	0.106446743516701
GO:0140789	histone phosphatase activity	25/2115	136/18639	0.183823529411765	1.61999374217772	0.0100688254168121	0.121213167517777
GO:0051537	2 iron, 2 sulfur cluster binding	8/2115	28/18639	0.285714285714286	2.51793313069909	0.0104758098019713	0.124911560686363
GO:0005542	folic acid binding	5/2115	13/18639	0.384615384615385	3.38952536824877	0.0110078716435038	0.126439039428135
GO:0043560	insulin receptor substrate binding	5/2115	13/18639	0.384615384615385	3.38952536824877	0.0110078716435038	0.126439039428135
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	5/2115	13/18639	0.384615384615385	3.38952536824877	0.0110078716435038	0.126439039428135
GO:0140666	annealing activity	5/2115	13/18639	0.384615384615385	3.38952536824877	0.0110078716435038	0.126439039428135
GO:0090482	vitamin transmembrane transporter activity	9/2115	34/18639	0.264705882352941	2.33279098873592	0.0115029562915123	0.130924557063394
GO:0051540	metal cluster binding	16/2115	77/18639	0.207792207792208	1.83122409505388	0.0116665329483413	0.131529047791154
GO:0000400	four-way junction DNA binding	6/2115	18/18639	0.333333333333333	2.93758865248227	0.0117661767992087	0.131529047791154
GO:0051117	ATPase binding	17/2115	84/18639	0.202380952380952	1.78353596757852	0.0123575689764914	0.136917489898825
GO:0038024	cargo receptor activity	14/2115	65/18639	0.215384615384615	1.89813420621931	0.0129695751665868	0.142175550667214
GO:0003785	actin monomer binding	8/2115	29/18639	0.275862068965517	2.43110785033015	0.0130592558520204	0.142175550667214
GO:0005154	epidermal growth factor receptor binding	9/2115	35/18639	0.257142857142857	2.26613981762918	0.0139630166920469	0.150022133349773
GO:0061749	forked DNA-dependent helicase activity	11/2115	47/18639	0.234042553191489	2.06256224535989	0.014286414505172	0.150022133349773
GO:1990518	single-stranded 3'-5' DNA helicase activity	11/2115	47/18639	0.234042553191489	2.06256224535989	0.014286414505172	0.150022133349773
GO:0015175	neutral L-amino acid transmembrane transporter activity	10/2115	41/18639	0.24390243902439	2.14945511157239	0.014315482975605	0.150022133349773
GO:0019902	phosphatase binding	32/2115	190/18639	0.168421052631579	1.48425531914894	0.0144461615465091	0.150022133349773
GO:0004622	lysophospholipase activity	7/2115	24/18639	0.291666666666667	2.57039007092199	0.0145236331651919	0.150022133349773
GO:0004386	helicase activity	27/2115	155/18639	0.174193548387097	1.53512697323267	0.0154230663469794	0.150022133349773
GO:0032036	myosin heavy chain binding	5/2115	14/18639	0.357142857142857	3.14741641337386	0.015548309160049	0.150022133349773
GO:0044548	S100 protein binding	5/2115	14/18639	0.357142857142857	3.14741641337386	0.015548309160049	0.150022133349773
GO:0070742	C2H2 zinc finger domain binding	5/2115	14/18639	0.357142857142857	3.14741641337386	0.015548309160049	0.150022133349773
GO:0003756	protein disulfide isomerase activity	6/2115	19/18639	0.315789473684211	2.78297872340426	0.0155773780634748	0.150022133349773
GO:0008301	DNA binding, bending	6/2115	19/18639	0.315789473684211	2.78297872340426	0.0155773780634748	0.150022133349773
GO:0008381	mechanosensitive monoatomic ion channel activity	6/2115	19/18639	0.315789473684211	2.78297872340426	0.0155773780634748	0.150022133349773
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	6/2115	19/18639	0.315789473684211	2.78297872340426	0.0155773780634748	0.150022133349773
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	6/2115	19/18639	0.315789473684211	2.78297872340426	0.0155773780634748	0.150022133349773
GO:0061135	endopeptidase regulator activity	31/2115	184/18639	0.168478260869565	1.48475948196115	0.0157951074807249	0.150957821113493
GO:0009378	four-way junction helicase activity	11/2115	48/18639	0.229166666666667	2.01959219858156	0.0166854348967741	0.155896749931053
GO:0036121	double-stranded DNA helicase activity	11/2115	48/18639	0.229166666666667	2.01959219858156	0.0166854348967741	0.155896749931053
GO:0043138	3'-5' DNA helicase activity	11/2115	48/18639	0.229166666666667	2.01959219858156	0.0166854348967741	0.155896749931053
GO:0035198	miRNA binding	10/2115	42/18639	0.238095238095238	2.09827760891591	0.0169295221230417	0.157005642207764
GO:0002020	protease binding	24/2115	136/18639	0.176470588235294	1.55519399249061	0.0185385380960868	0.168929476435229
GO:0035591	signaling adaptor activity	23/2115	129/18639	0.178294573643411	1.57126834900214	0.018606710192241	0.168929476435229
GO:0001618	virus receptor activity	16/2115	81/18639	0.197530864197531	1.74079327554505	0.0186200221629885	0.168929476435229
GO:0030145	manganese ion binding	14/2115	68/18639	0.205882352941176	1.81439299123905	0.019014164364036	0.170652170769157
GO:0001094	TFIID-class transcription factor complex binding	4/2115	10/18639	0.4	3.52510638297872	0.0197640293622426	0.170652170769157
GO:0003680	minor groove of adenine-thymine-rich DNA binding	4/2115	10/18639	0.4	3.52510638297872	0.0197640293622426	0.170652170769157
GO:0005345	purine nucleobase transmembrane transporter activity	4/2115	10/18639	0.4	3.52510638297872	0.0197640293622426	0.170652170769157
GO:0015924	mannosyl-oligosaccharide mannosidase activity	4/2115	10/18639	0.4	3.52510638297872	0.0197640293622426	0.170652170769157
GO:0031996	thioesterase binding	4/2115	10/18639	0.4	3.52510638297872	0.0197640293622426	0.170652170769157
GO:0050815	phosphoserine residue binding	4/2115	10/18639	0.4	3.52510638297872	0.0197640293622426	0.170652170769157
GO:0008514	organic anion transmembrane transporter activity	42/2115	269/18639	0.156133828996283	1.37597089298426	0.0200376999769444	0.171735864334145
GO:0000339	RNA cap binding	6/2115	20/18639	0.3	2.64382978723404	0.0201638754449834	0.171735864334145
GO:0140272	exogenous protein binding	16/2115	82/18639	0.195121951219512	1.71956408925791	0.0207732724060184	0.17351148789259
GO:0004559	alpha-mannosidase activity	5/2115	15/18639	0.333333333333333	2.93758865248227	0.0211847900094472	0.17351148789259
GO:0019887	protein kinase regulator activity	40/2115	255/18639	0.156862745098039	1.38239465999166	0.0212636017475589	0.17351148789259
GO:0046906	tetrapyrrole binding	26/2115	152/18639	0.171052631578947	1.50744680851064	0.0213291976953392	0.17351148789259
GO:0030170	pyridoxal phosphate binding	12/2115	56/18639	0.214285714285714	1.88844984802432	0.021340243130278	0.17351148789259
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	17/2115	89/18639	0.191011235955056	1.68333731771456	0.0213424673605901	0.17351148789259
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	17/2115	89/18639	0.191011235955056	1.68333731771456	0.0213424673605901	0.17351148789259
GO:0017022	myosin binding	15/2115	76/18639	0.197368421052632	1.73936170212766	0.0223959235253895	0.179741642652485
GO:0051536	iron-sulfur cluster binding	15/2115	76/18639	0.197368421052632	1.73936170212766	0.0223959235253895	0.179741642652485
GO:0005507	copper ion binding	13/2115	63/18639	0.206349206349206	1.81850726106045	0.0228929944336831	0.182560694464785
GO:0031369	translation initiation factor binding	8/2115	32/18639	0.25	2.2031914893617	0.0235730576848746	0.184016096132499
GO:0043425	bHLH transcription factor binding	8/2115	32/18639	0.25	2.2031914893617	0.0235730576848746	0.184016096132499
GO:0140793	histone H2AXY142 phosphatase activity	17/2115	90/18639	0.188888888888889	1.66463356973995	0.0236212419627787	0.184016096132499
GO:0005109	frizzled binding	9/2115	38/18639	0.236842105263158	2.08723404255319	0.0236634117231088	0.184016096132499
GO:0008028	monocarboxylic acid transmembrane transporter activity	14/2115	70/18639	0.2	1.76255319148936	0.0240918224414568	0.186191121584592
GO:0070279	vitamin B6 binding	12/2115	57/18639	0.210526315789474	1.85531914893617	0.0243278604089085	0.186861848048794
GO:0004364	glutathione transferase activity	7/2115	27/18639	0.259259259259259	2.28479117415288	0.0275822546919609	0.202582328323349
GO:0008320	protein transmembrane transporter activity	7/2115	27/18639	0.259259259259259	2.28479117415288	0.0275822546919609	0.202582328323349
GO:0061980	regulatory RNA binding	12/2115	58/18639	0.206896551724138	1.82333088774762	0.0276109322370327	0.202582328323349
GO:0005159	insulin-like growth factor receptor binding	5/2115	16/18639	0.3125	2.75398936170213	0.028000104907157	0.202582328323349
GO:0005324	long-chain fatty acid transmembrane transporter activity	5/2115	16/18639	0.3125	2.75398936170213	0.028000104907157	0.202582328323349
GO:0015923	mannosidase activity	5/2115	16/18639	0.3125	2.75398936170213	0.028000104907157	0.202582328323349
GO:0017070	U6 snRNA binding	5/2115	16/18639	0.3125	2.75398936170213	0.028000104907157	0.202582328323349
GO:0004523	RNA-DNA hybrid ribonuclease activity	4/2115	11/18639	0.363636363636364	3.20464216634429	0.0283162200132476	0.202582328323349
GO:0015205	nucleobase transmembrane transporter activity	4/2115	11/18639	0.363636363636364	3.20464216634429	0.0283162200132476	0.202582328323349
GO:0034056	estrogen response element binding	4/2115	11/18639	0.363636363636364	3.20464216634429	0.0283162200132476	0.202582328323349
GO:0034511	U3 snoRNA binding	4/2115	11/18639	0.363636363636364	3.20464216634429	0.0283162200132476	0.202582328323349
GO:0070990	snRNP binding	4/2115	11/18639	0.363636363636364	3.20464216634429	0.0283162200132476	0.202582328323349
GO:0005080	protein kinase C binding	11/2115	52/18639	0.211538461538462	1.86423895253683	0.029347880409904	0.208770149279545
GO:0020037	heme binding	24/2115	142/18639	0.169014084507042	1.4894815702727	0.0297755377123481	0.210615667886214
GO:0051020	GTPase binding	47/2115	315/18639	0.149206349206349	1.31492063492064	0.0304132697346116	0.21391805453783
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	22/2115	128/18639	0.171875	1.51469414893617	0.0307011258112717	0.214736366009565
GO:0030331	nuclear estrogen receptor binding	9/2115	40/18639	0.225	1.98287234042553	0.0323326326067275	0.22489142235346
GO:0042562	hormone binding	17/2115	94/18639	0.180851063829787	1.59379809868719	0.0346057827363084	0.239372596606951
GO:0061134	peptidase regulator activity	35/2115	226/18639	0.154867256637168	1.36480888721521	0.0349481708793898	0.240412691983495
GO:0004550	nucleoside diphosphate kinase activity	5/2115	17/18639	0.294117647058824	2.59198998748436	0.0360576176534659	0.246689274875078
GO:0017069	snRNA binding	11/2115	54/18639	0.203703703703704	1.79519306540583	0.0377620865930794	0.253899546631221
GO:0003689	DNA clamp loader activity	26/2115	160/18639	0.1625	1.43207446808511	0.0378336754298628	0.253899546631221
GO:0004721	phosphoprotein phosphatase activity	28/2115	175/18639	0.16	1.41004255319149	0.0382810661803411	0.253899546631221
GO:0004859	phospholipase inhibitor activity	4/2115	12/18639	0.333333333333333	2.93758865248227	0.0387428752017349	0.253899546631221
GO:0010853	cyclase activator activity	4/2115	12/18639	0.333333333333333	2.93758865248227	0.0387428752017349	0.253899546631221
GO:0070008	serine-type exopeptidase activity	4/2115	12/18639	0.333333333333333	2.93758865248227	0.0387428752017349	0.253899546631221
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/2115	12/18639	0.333333333333333	2.93758865248227	0.0387428752017349	0.253899546631221
GO:0061631	ubiquitin conjugating enzyme activity	8/2115	35/18639	0.228571428571429	2.01434650455927	0.0389329173245189	0.253899546631221
GO:0005283	amino acid:sodium symporter activity	6/2115	23/18639	0.260869565217391	2.29898242368178	0.0391394668528959	0.253899546631221
GO:0017134	fibroblast growth factor binding	6/2115	23/18639	0.260869565217391	2.29898242368178	0.0391394668528959	0.253899546631221
GO:0016879	ligase activity, forming carbon-nitrogen bonds	10/2115	48/18639	0.208333333333333	1.83599290780142	0.0404199912341221	0.259713094231953
GO:0003777	microtubule motor activity	13/2115	68/18639	0.191176470588235	1.68479349186483	0.0404505218652004	0.259713094231953
GO:0003725	double-stranded RNA binding	14/2115	75/18639	0.186666666666667	1.64504964539007	0.0411059686118533	0.262574860724696
GO:0031492	nucleosomal DNA binding	9/2115	42/18639	0.214285714285714	1.88844984802432	0.042982801527055	0.271790239958954
GO:0051879	Hsp90 protein binding	9/2115	42/18639	0.214285714285714	1.88844984802432	0.042982801527055	0.271790239958954
GO:0004869	cysteine-type endopeptidase inhibitor activity	8/2115	36/18639	0.222222222222222	1.95839243498818	0.0452591828086528	0.282793036615178
GO:0000900	mRNA regulatory element binding translation repressor activity	5/2115	18/18639	0.277777777777778	2.44799054373522	0.0454004795204879	0.282793036615178
GO:0031690	adrenergic receptor binding	5/2115	18/18639	0.277777777777778	2.44799054373522	0.0454004795204879	0.282793036615178
GO:0060590	ATPase regulator activity	10/2115	49/18639	0.204081632653061	1.79852366478506	0.0458167009155025	0.283972819535689
GO:0051721	protein phosphatase 2A binding	7/2115	30/18639	0.233333333333333	2.05631205673759	0.0469146211175523	0.287745730220846
GO:0001091	RNA polymerase II general transcription initiation factor binding	6/2115	24/18639	0.25	2.2031914893617	0.0473447447487973	0.287745730220846
GO:0005540	hyaluronic acid binding	6/2115	24/18639	0.25	2.2031914893617	0.0473447447487973	0.287745730220846
GO:0050699	WW domain binding	6/2115	24/18639	0.25	2.2031914893617	0.0473447447487973	0.287745730220846
GO:0004725	protein tyrosine phosphatase activity	17/2115	98/18639	0.173469387755102	1.5287451150673	0.0489325842414378	0.295959398407151
GO:0031406	carboxylic acid binding	29/2115	187/18639	0.155080213903743	1.36668562976448	0.0503110871773057	0.298780693454191
GO:0019207	kinase regulator activity	42/2115	287/18639	0.146341463414634	1.28967306694344	0.050617493849701	0.298780693454191
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	4/2115	13/18639	0.307692307692308	2.71162029459902	0.0510695434498377	0.298780693454191
GO:0019104	DNA N-glycosylase activity	4/2115	13/18639	0.307692307692308	2.71162029459902	0.0510695434498377	0.298780693454191
GO:0019855	calcium channel inhibitor activity	4/2115	13/18639	0.307692307692308	2.71162029459902	0.0510695434498377	0.298780693454191
GO:0061459	L-arginine transmembrane transporter activity	4/2115	13/18639	0.307692307692308	2.71162029459902	0.0510695434498377	0.298780693454191
GO:0140410	monoatomic cation:bicarbonate symporter activity	4/2115	13/18639	0.307692307692308	2.71162029459902	0.0510695434498377	0.298780693454191
GO:0046943	carboxylic acid transmembrane transporter activity	29/2115	188/18639	0.154255319148936	1.35941602535084	0.0532890246965811	0.308878976482035
GO:0140597	protein carrier chaperone	29/2115	188/18639	0.154255319148936	1.35941602535084	0.0532890246965811	0.308878976482035
GO:0044325	transmembrane transporter binding	22/2115	136/18639	0.161764705882353	1.4255944931164	0.0549758819701474	0.317188037910712
GO:0015245	fatty acid transmembrane transporter activity	5/2115	19/18639	0.263157894736842	2.31914893617021	0.0560515871837069	0.319472494251423
GO:0050145	nucleoside monophosphate kinase activity	5/2115	19/18639	0.263157894736842	2.31914893617021	0.0560515871837069	0.319472494251423
GO:0005342	organic acid transmembrane transporter activity	29/2115	189/18639	0.153439153439153	1.35222334796803	0.0563925089693007	0.319472494251423
GO:0043177	organic acid binding	29/2115	189/18639	0.153439153439153	1.35222334796803	0.0563925089693007	0.319472494251423
GO:0030695	GTPase regulator activity	67/2115	489/18639	0.137014314928425	1.20747509028412	0.0585661362108718	0.330291903315367
GO:0042162	telomeric DNA binding	8/2115	38/18639	0.210526315789474	1.85531914893617	0.0598388945983194	0.335816534528009
GO:0042379	chemokine receptor binding	13/2115	72/18639	0.180555555555556	1.5911938534279	0.0600821914810495	0.335816534528009
GO:0060589	nucleoside-triphosphatase regulator activity	67/2115	490/18639	0.136734693877551	1.20501085540599	0.0605845811443796	0.337119535967837
GO:0003774	cytoskeletal motor activity	24/2115	153/18639	0.156862745098039	1.38239465999166	0.0627711129448957	0.346521576832778
GO:0008009	chemokine activity	9/2115	45/18639	0.2	1.76255319148936	0.0629813995521065	0.346521576832778
GO:0022884	macromolecule transmembrane transporter activity	7/2115	32/18639	0.21875	1.92779255319149	0.0636581171497914	0.346521576832778
GO:0051059	NF-kappaB binding	7/2115	32/18639	0.21875	1.92779255319149	0.0636581171497914	0.346521576832778
GO:0070717	poly-purine tract binding	7/2115	32/18639	0.21875	1.92779255319149	0.0636581171497914	0.346521576832778
GO:0005085	guanyl-nucleotide exchange factor activity	34/2115	230/18639	0.147826086956522	1.30275670675301	0.0646364560871683	0.349265395433859
GO:0030159	signaling receptor complex adaptor activity	10/2115	52/18639	0.192307692307692	1.69476268412439	0.0648451751195244	0.349265395433859
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	4/2115	14/18639	0.285714285714286	2.51793313069909	0.0652780371657533	0.349265395433859
GO:1990825	sequence-specific mRNA binding	4/2115	14/18639	0.285714285714286	2.51793313069909	0.0652780371657533	0.349265395433859
GO:0016829	lyase activity	30/2115	200/18639	0.15	1.32191489361702	0.0676094858828035	0.360200324788383
GO:0016776	phosphotransferase activity, phosphate group as acceptor	8/2115	39/18639	0.205128205128205	1.80774686306601	0.0681170262220958	0.361366596737559
GO:0031491	nucleosome binding	13/2115	74/18639	0.175675675675676	1.54818861414606	0.0719506617789425	0.379626654904506
GO:0004864	protein phosphatase inhibitor activity	10/2115	53/18639	0.188679245283019	1.66278602970695	0.0721654503732209	0.379626654904506
GO:0050840	extracellular matrix binding	12/2115	67/18639	0.17910447761194	1.5784058431248	0.0725437488513461	0.380019973062282
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	7/2115	33/18639	0.212121212121212	1.86937459703417	0.0732276004558707	0.380418903613071
GO:0019956	chemokine binding	7/2115	33/18639	0.212121212121212	1.86937459703417	0.0732276004558707	0.380418903613071
GO:0003727	single-stranded RNA binding	15/2115	89/18639	0.168539325842697	1.48529763327755	0.0755922065865797	0.390619562881271
GO:0140713	histone chaperone activity	25/2115	164/18639	0.152439024390244	1.34340944473275	0.0766991629881759	0.390619562881271
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	8/2115	40/18639	0.2	1.76255319148936	0.0770631246259377	0.390619562881271
GO:0061791	GTPase motor activity	8/2115	40/18639	0.2	1.76255319148936	0.0770631246259377	0.390619562881271
GO:0071949	FAD binding	8/2115	40/18639	0.2	1.76255319148936	0.0770631246259377	0.390619562881271
GO:1990606	membrane scission GTPase motor activity	8/2115	40/18639	0.2	1.76255319148936	0.0770631246259377	0.390619562881271
GO:0023026	MHC class II protein complex binding	6/2115	27/18639	0.222222222222222	1.95839243498818	0.0779039161891136	0.393126219259298
GO:0001664	G protein-coupled receptor binding	42/2115	297/18639	0.141414141414141	1.24624973135611	0.078243457013445	0.393126219259298
GO:0106310	protein serine kinase activity	50/2115	361/18639	0.138504155124654	1.22060470324748	0.0790575521572248	0.393126219259298
GO:0001784	phosphotyrosine residue binding	9/2115	47/18639	0.191489361702128	1.68755092802173	0.0791276415761527	0.393126219259298
GO:0005504	fatty acid binding	9/2115	47/18639	0.191489361702128	1.68755092802173	0.0791276415761527	0.393126219259298
GO:0003925	G protein activity	10/2115	54/18639	0.185185185185185	1.63199369582348	0.0799843966868895	0.394253797842463
GO:0051287	NAD binding	10/2115	54/18639	0.185185185185185	1.63199369582348	0.0799843966868895	0.394253797842463
GO:0019200	carbohydrate kinase activity	5/2115	21/18639	0.238095238095238	2.09827760891591	0.0812727966334003	0.397666232104238
GO:0140161	monocarboxylate:sodium symporter activity	4/2115	15/18639	0.266666666666667	2.35007092198582	0.0813119452225919	0.397666232104238
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	7/2115	34/18639	0.205882352941176	1.81439299123905	0.0835985124162936	0.407258122743967
GO:0140658	ATP-dependent chromatin remodeler activity	24/2115	158/18639	0.151898734177215	1.33864799353622	0.084095967990001	0.408093612106516
GO:0140318	protein transporter activity	8/2115	41/18639	0.195121951219512	1.71956408925791	0.0866784382466546	0.41900156248962
GO:0015179	L-amino acid transmembrane transporter activity	11/2115	62/18639	0.17741935483871	1.56355525051476	0.0877701741890976	0.419206618595532
GO:0072341	modified amino acid binding	15/2115	91/18639	0.164835164835165	1.45265372924947	0.0879952991832196	0.419206618595532
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	9/2115	48/18639	0.1875	1.65239361702128	0.0880601762704673	0.419206618595532
GO:0140693	molecular condensate scaffold activity	9/2115	48/18639	0.1875	1.65239361702128	0.0880601762704673	0.419206618595532
GO:0004497	monooxygenase activity	17/2115	106/18639	0.160377358490566	1.4133681252509	0.0891198213858413	0.422596844325866
GO:0016866	intramolecular transferase activity	6/2115	28/18639	0.214285714285714	1.88844984802432	0.0900728743347017	0.422596844325866
GO:0046875	ephrin receptor binding	6/2115	28/18639	0.214285714285714	1.88844984802432	0.0900728743347017	0.422596844325866
GO:0004860	protein kinase inhibitor activity	14/2115	84/18639	0.166666666666667	1.46879432624113	0.0902848611948518	0.422596844325866
GO:0019955	cytokine binding	22/2115	144/18639	0.152777777777778	1.34639479905437	0.0904600273796581	0.422596844325866
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	48/2115	349/18639	0.137535816618911	1.21207096262879	0.091638462172583	0.422656766875179
GO:0016922	nuclear receptor binding	21/2115	137/18639	0.153284671532847	1.35086193508309	0.0938185860126475	0.422656766875179
GO:0005343	organic acid:sodium symporter activity	7/2115	35/18639	0.2	1.76255319148936	0.0947649111892373	0.422656766875179
GO:0005522	profilin binding	3/2115	10/18639	0.3	2.64382978723404	0.0951990481300324	0.422656766875179
GO:0005528	FK506 binding	3/2115	10/18639	0.3	2.64382978723404	0.0951990481300324	0.422656766875179
GO:0015658	branched-chain amino acid transmembrane transporter activity	3/2115	10/18639	0.3	2.64382978723404	0.0951990481300324	0.422656766875179
GO:0016868	intramolecular phosphotransferase activity	3/2115	10/18639	0.3	2.64382978723404	0.0951990481300324	0.422656766875179
GO:0030957	Tat protein binding	3/2115	10/18639	0.3	2.64382978723404	0.0951990481300324	0.422656766875179
GO:0031957	very long-chain fatty acid-CoA ligase activity	3/2115	10/18639	0.3	2.64382978723404	0.0951990481300324	0.422656766875179
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	3/2115	10/18639	0.3	2.64382978723404	0.0951990481300324	0.422656766875179
GO:0035374	chondroitin sulfate binding	3/2115	10/18639	0.3	2.64382978723404	0.0951990481300324	0.422656766875179
GO:0043208	glycosphingolipid binding	3/2115	10/18639	0.3	2.64382978723404	0.0951990481300324	0.422656766875179
GO:0051880	G-quadruplex DNA binding	3/2115	10/18639	0.3	2.64382978723404	0.0951990481300324	0.422656766875179
GO:0140135	mechanosensitive monoatomic cation channel activity	3/2115	10/18639	0.3	2.64382978723404	0.0951990481300324	0.422656766875179
GO:0004520	DNA endonuclease activity	8/2115	42/18639	0.19047619047619	1.67862208713273	0.0969597645336191	0.423383492981774
GO:0016859	cis-trans isomerase activity	8/2115	42/18639	0.19047619047619	1.67862208713273	0.0969597645336191	0.423383492981774
GO:0042056	chemoattractant activity	8/2115	42/18639	0.19047619047619	1.67862208713273	0.0969597645336191	0.423383492981774
GO:0035402	histone H3T11 kinase activity	35/2115	247/18639	0.1417004048583	1.24877250409165	0.0981799103404594	0.423383492981774
GO:0001221	transcription coregulator binding	18/2115	115/18639	0.156521739130435	1.37938945420907	0.0982849745665055	0.423383492981774
GO:0004866	endopeptidase inhibitor activity	24/2115	161/18639	0.149068322981366	1.31370424210387	0.0989734523472315	0.423383492981774
GO:0008142	oxysterol binding	4/2115	16/18639	0.25	2.2031914893617	0.09908255866107	0.423383492981774
GO:0015378	sodium:chloride symporter activity	4/2115	16/18639	0.25	2.2031914893617	0.09908255866107	0.423383492981774
GO:0043023	ribosomal large subunit binding	4/2115	16/18639	0.25	2.2031914893617	0.09908255866107	0.423383492981774
GO:0055102	lipase inhibitor activity	4/2115	16/18639	0.25	2.2031914893617	0.09908255866107	0.423383492981774
GO:0097027	ubiquitin-protein transferase activator activity	4/2115	16/18639	0.25	2.2031914893617	0.09908255866107	0.423383492981774
GO:0030414	peptidase inhibitor activity	25/2115	169/18639	0.14792899408284	1.3036636031726	0.100300438730631	0.427129759492347
GO:0051219	phosphoprotein binding	15/2115	93/18639	0.161290322580645	1.42141386410432	0.101617689444439	0.429799809251278
GO:0140299	molecular sensor activity	12/2115	71/18639	0.169014084507042	1.4894815702727	0.102445438937845	0.429799809251278
GO:0031072	heat shock protein binding	20/2115	131/18639	0.152671755725191	1.3454604515186	0.103184632124032	0.429799809251278
GO:0004629	phospholipase C activity	6/2115	29/18639	0.206896551724138	1.82333088774762	0.103208491010482	0.429799809251278
GO:0005416	amino acid:monoatomic cation symporter activity	6/2115	29/18639	0.206896551724138	1.82333088774762	0.103208491010482	0.429799809251278
GO:0051861	glycolipid binding	6/2115	29/18639	0.206896551724138	1.82333088774762	0.103208491010482	0.429799809251278
GO:0015294	solute:monoatomic cation symporter activity	18/2115	116/18639	0.155172413793103	1.36749816581071	0.104618103904264	0.429799809251278
GO:0016504	peptidase activator activity	10/2115	57/18639	0.175438596491228	1.54609929078014	0.106445116240139	0.429799809251278
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	7/2115	36/18639	0.194444444444444	1.71359338061466	0.106714569763861	0.429799809251278
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	7/2115	36/18639	0.194444444444444	1.71359338061466	0.106714569763861	0.429799809251278
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	7/2115	36/18639	0.194444444444444	1.71359338061466	0.106714569763861	0.429799809251278
GO:0004712	protein serine/threonine/tyrosine kinase activity	8/2115	43/18639	0.186046511627907	1.63958436417615	0.107899533559078	0.429799809251278
GO:0008200	ion channel inhibitor activity	8/2115	43/18639	0.186046511627907	1.63958436417615	0.107899533559078	0.429799809251278
GO:0015370	solute:sodium symporter activity	13/2115	79/18639	0.164556962025316	1.45020199299758	0.107902510630355	0.429799809251278
GO:0016835	carbon-oxygen lyase activity	13/2115	79/18639	0.164556962025316	1.45020199299758	0.107902510630355	0.429799809251278
GO:0004620	phospholipase activity	17/2115	109/18639	0.155963302752294	1.37446808510638	0.108456761339516	0.429799809251278
GO:0005125	cytokine activity	33/2115	234/18639	0.141025641025641	1.24282596835788	0.110775822169383	0.429799809251278
GO:0019208	phosphatase regulator activity	18/2115	117/18639	0.153846153846154	1.35581014729951	0.111198645578761	0.429799809251278
GO:1990782	protein tyrosine kinase binding	18/2115	117/18639	0.153846153846154	1.35581014729951	0.111198645578761	0.429799809251278
GO:0099186	structural constituent of postsynapse	5/2115	23/18639	0.217391304347826	1.91581868640148	0.111532572687066	0.429799809251278
GO:0015171	amino acid transmembrane transporter activity	16/2115	102/18639	0.156862745098039	1.38239465999166	0.112408072524809	0.429799809251278
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	34/2115	243/18639	0.139917695473251	1.23306190351108	0.115652399401081	0.429799809251278
GO:0004867	serine-type endopeptidase inhibitor activity	15/2115	95/18639	0.157894736842105	1.39148936170213	0.116462577405425	0.429799809251278
GO:0001968	fibronectin binding	6/2115	30/18639	0.2	1.76255319148936	0.117281958483715	0.429799809251278
GO:0008187	poly-pyrimidine tract binding	6/2115	30/18639	0.2	1.76255319148936	0.117281958483715	0.429799809251278
GO:0004659	prenyltransferase activity	4/2115	17/18639	0.235294117647059	2.07359198998748	0.118474848201871	0.429799809251278
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	4/2115	17/18639	0.235294117647059	2.07359198998748	0.118474848201871	0.429799809251278
GO:0016018	cyclosporin A binding	4/2115	17/18639	0.235294117647059	2.07359198998748	0.118474848201871	0.429799809251278
GO:0036041	long-chain fatty acid binding	4/2115	17/18639	0.235294117647059	2.07359198998748	0.118474848201871	0.429799809251278
GO:0046965	nuclear retinoid X receptor binding	4/2115	17/18639	0.235294117647059	2.07359198998748	0.118474848201871	0.429799809251278
GO:0070492	oligosaccharide binding	4/2115	17/18639	0.235294117647059	2.07359198998748	0.118474848201871	0.429799809251278
GO:0023023	MHC protein complex binding	7/2115	37/18639	0.189189189189189	1.66728004600345	0.119429268566533	0.429799809251278
GO:0001223	transcription coactivator binding	8/2115	44/18639	0.181818181818182	1.60232108317215	0.11948594343936	0.429799809251278
GO:0016248	channel inhibitor activity	8/2115	44/18639	0.181818181818182	1.60232108317215	0.11948594343936	0.429799809251278
GO:0000099	sulfur amino acid transmembrane transporter activity	3/2115	11/18639	0.272727272727273	2.40348162475822	0.120280108673827	0.429799809251278
GO:0008199	ferric iron binding	3/2115	11/18639	0.272727272727273	2.40348162475822	0.120280108673827	0.429799809251278
GO:0010854	adenylate cyclase regulator activity	3/2115	11/18639	0.272727272727273	2.40348162475822	0.120280108673827	0.429799809251278
GO:0015173	aromatic amino acid transmembrane transporter activity	3/2115	11/18639	0.272727272727273	2.40348162475822	0.120280108673827	0.429799809251278
GO:0016176	superoxide-generating NADPH oxidase activator activity	3/2115	11/18639	0.272727272727273	2.40348162475822	0.120280108673827	0.429799809251278
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	3/2115	11/18639	0.272727272727273	2.40348162475822	0.120280108673827	0.429799809251278
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	3/2115	11/18639	0.272727272727273	2.40348162475822	0.120280108673827	0.429799809251278
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	3/2115	11/18639	0.272727272727273	2.40348162475822	0.120280108673827	0.429799809251278
GO:0019206	nucleoside kinase activity	3/2115	11/18639	0.272727272727273	2.40348162475822	0.120280108673827	0.429799809251278
GO:0019215	intermediate filament binding	3/2115	11/18639	0.272727272727273	2.40348162475822	0.120280108673827	0.429799809251278
GO:0045294	alpha-catenin binding	3/2115	11/18639	0.272727272727273	2.40348162475822	0.120280108673827	0.429799809251278
GO:0047676	arachidonate-CoA ligase activity	3/2115	11/18639	0.272727272727273	2.40348162475822	0.120280108673827	0.429799809251278
GO:0033192	calmodulin-dependent protein phosphatase activity	13/2115	81/18639	0.160493827160494	1.41439453638035	0.124811118898052	0.429799809251278
GO:0140791	histone H2AXS140 phosphatase activity	13/2115	81/18639	0.160493827160494	1.41439453638035	0.124811118898052	0.429799809251278
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	13/2115	81/18639	0.160493827160494	1.41439453638035	0.124811118898052	0.429799809251278
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	13/2115	81/18639	0.160493827160494	1.41439453638035	0.124811118898052	0.429799809251278
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	13/2115	81/18639	0.160493827160494	1.41439453638035	0.124811118898052	0.429799809251278
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	13/2115	81/18639	0.160493827160494	1.41439453638035	0.124811118898052	0.429799809251278
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	13/2115	81/18639	0.160493827160494	1.41439453638035	0.124811118898052	0.429799809251278
GO:1990439	MAP kinase serine/threonine phosphatase activity	13/2115	81/18639	0.160493827160494	1.41439453638035	0.124811118898052	0.429799809251278
GO:0004676	3-phosphoinositide-dependent protein kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:0004711	ribosomal protein S6 kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:0035175	histone H3S10 kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:0035979	histone H2AXS139 kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:0044022	histone H3S28 kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:0044023	histone H4S1 kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:0044024	histone H2AS1 kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:0044025	histone H2BS14 kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:0072354	histone H3T3 kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:0072371	histone H2AS121 kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:0072518	Rho-dependent protein serine/threonine kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:0140823	histone H2BS36 kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:0140855	histone H3S57 kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:0140995	histone H2A kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:0140997	histone H4 kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:0140998	histone H2B kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:1990244	histone H2AT120 kinase activity	34/2115	245/18639	0.138775510204082	1.22299609205384	0.125301062601211	0.429799809251278
GO:0004879	nuclear receptor activity	10/2115	59/18639	0.169491525423729	1.49368914532997	0.126558409026843	0.43292657951259
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	5/2115	24/18639	0.208333333333333	1.83599290780142	0.128424106355032	0.438111665276567
GO:0004677	DNA-dependent protein kinase activity	34/2115	246/18639	0.138211382113821	1.21802456322436	0.130308026080494	0.440888593399308
GO:0140857	histone H3T45 kinase activity	34/2115	246/18639	0.138211382113821	1.21802456322436	0.130308026080494	0.440888593399308
GO:0000510	H3-H4 histone complex chaperone activity	22/2115	151/18639	0.145695364238411	1.28397914611808	0.131649035264048	0.440888593399308
GO:0140584	chromatin extrusion motor activity	22/2115	151/18639	0.145695364238411	1.28397914611808	0.131649035264048	0.440888593399308
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	22/2115	151/18639	0.145695364238411	1.28397914611808	0.131649035264048	0.440888593399308
GO:0140849	ATP-dependent H2AZ histone chaperone activity	22/2115	151/18639	0.145695364238411	1.28397914611808	0.131649035264048	0.440888593399308
GO:0141110	transporter inhibitor activity	8/2115	45/18639	0.177777777777778	1.56671394799054	0.131703142117685	0.440888593399308
GO:0072349	modified amino acid transmembrane transporter activity	6/2115	31/18639	0.193548387096774	1.70569663692519	0.132256146025764	0.441559186198017
GO:0042887	amide transmembrane transporter activity	7/2115	38/18639	0.184210526315789	1.62340425531915	0.132885159462581	0.442479307572212
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	13/2115	82/18639	0.158536585365854	1.39714582252205	0.133797778521806	0.443160896056351
GO:0033549	MAP kinase phosphatase activity	13/2115	82/18639	0.158536585365854	1.39714582252205	0.133797778521806	0.443160896056351
GO:0031490	chromatin DNA binding	19/2115	128/18639	0.1484375	1.30814494680851	0.134313899534747	0.443696575771778
GO:0033218	amide binding	34/2115	247/18639	0.137651821862348	1.21309328968903	0.135436457700969	0.445056286198459
GO:0035403	histone H3T6 kinase activity	34/2115	247/18639	0.137651821862348	1.21309328968903	0.135436457700969	0.445056286198459
GO:0098531	ligand-modulated transcription factor activity	10/2115	60/18639	0.166666666666667	1.46879432624113	0.137335340300469	0.448509654358937
GO:0019210	kinase inhibitor activity	14/2115	90/18639	0.155555555555556	1.37087470449173	0.13773246816801	0.448509654358937
GO:0015616	DNA translocase activity	22/2115	152/18639	0.144736842105263	1.27553191489362	0.138316610017197	0.448509654358937
GO:0140674	ATP-dependent histone chaperone activity	22/2115	152/18639	0.144736842105263	1.27553191489362	0.138316610017197	0.448509654358937
GO:0003746	translation elongation factor activity	4/2115	18/18639	0.222222222222222	1.95839243498818	0.139353239253695	0.448509654358937
GO:0015373	monoatomic anion:sodium symporter activity	4/2115	18/18639	0.222222222222222	1.95839243498818	0.139353239253695	0.448509654358937
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	4/2115	18/18639	0.222222222222222	1.95839243498818	0.139353239253695	0.448509654358937
GO:0030228	lipoprotein particle receptor activity	4/2115	18/18639	0.222222222222222	1.95839243498818	0.139353239253695	0.448509654358937
GO:0003713	transcription coactivator activity	35/2115	256/18639	0.13671875	1.20487034574468	0.140357235083814	0.450482968829267
GO:0004679	AMP-activated protein kinase activity	34/2115	248/18639	0.137096774193548	1.20820178448868	0.140685975089651	0.450482968829267
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	13/2115	83/18639	0.156626506024096	1.38031274032299	0.143132561466192	0.45472635836285
GO:0061775	cohesin loader activity	22/2115	153/18639	0.143790849673203	1.26719510499235	0.145177155932678	0.45472635836285
GO:0042578	phosphoric ester hydrolase activity	48/2115	363/18639	0.132231404958678	1.1653244241252	0.146175936898331	0.45472635836285
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	5/2115	25/18639	0.2	1.76255319148936	0.146396371508281	0.45472635836285
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	7/2115	39/18639	0.179487179487179	1.58177850518276	0.147053188608937	0.45472635836285
GO:0005527	macrolide binding	3/2115	12/18639	0.25	2.2031914893617	0.147459186497857	0.45472635836285
GO:0016801	hydrolase activity, acting on ether bonds	3/2115	12/18639	0.25	2.2031914893617	0.147459186497857	0.45472635836285
GO:0016803	ether hydrolase activity	3/2115	12/18639	0.25	2.2031914893617	0.147459186497857	0.45472635836285
GO:0016840	carbon-nitrogen lyase activity	3/2115	12/18639	0.25	2.2031914893617	0.147459186497857	0.45472635836285
GO:0017166	vinculin binding	3/2115	12/18639	0.25	2.2031914893617	0.147459186497857	0.45472635836285
GO:0035259	nuclear glucocorticoid receptor binding	3/2115	12/18639	0.25	2.2031914893617	0.147459186497857	0.45472635836285
GO:0042301	phosphate ion binding	3/2115	12/18639	0.25	2.2031914893617	0.147459186497857	0.45472635836285
GO:0045295	gamma-catenin binding	3/2115	12/18639	0.25	2.2031914893617	0.147459186497857	0.45472635836285
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	3/2115	12/18639	0.25	2.2031914893617	0.147459186497857	0.45472635836285
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/2115	12/18639	0.25	2.2031914893617	0.147459186497857	0.45472635836285
GO:0015026	coreceptor activity	10/2115	61/18639	0.163934426229508	1.44471573072898	0.148577581907957	0.457049465721776
GO:0016298	lipase activity	19/2115	130/18639	0.146153846153846	1.28801963993453	0.149284883949766	0.458099692904676
GO:0015293	symporter activity	21/2115	146/18639	0.143835616438356	1.26758962401632	0.1514735030644	0.463679280774154
GO:0017018	myosin phosphatase activity	13/2115	84/18639	0.154761904761905	1.36388044579534	0.152808900952493	0.466626204859808
GO:0031267	small GTPase binding	38/2115	283/18639	0.134275618374558	1.18333959852643	0.154447941696246	0.47048375426691
GO:0043495	protein-membrane adaptor activity	8/2115	47/18639	0.170212765957447	1.50004526935265	0.157947615490106	0.479976734450516
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	4/2115	19/18639	0.210526315789474	1.85531914893617	0.161567013139026	0.48842953350229
GO:0008574	plus-end-directed microtubule motor activity	4/2115	19/18639	0.210526315789474	1.85531914893617	0.161567013139026	0.48842953350229
GO:0004177	aminopeptidase activity	7/2115	40/18639	0.175	1.54223404255319	0.161899565817452	0.48842953350229
GO:0004674	protein serine/threonine kinase activity	56/2115	433/18639	0.12933025404157	1.1397572600855	0.164174672260614	0.490242329320535
GO:0140311	protein sequestering activity	6/2115	33/18639	0.181818181818182	1.60232108317215	0.16472176258751	0.490242329320535
GO:0004435	phosphatidylinositol phospholipase C activity	5/2115	26/18639	0.192307692307692	1.69476268412439	0.165366620737561	0.490242329320535
GO:0004529	DNA exonuclease activity	5/2115	26/18639	0.192307692307692	1.69476268412439	0.165366620737561	0.490242329320535
GO:0008143	poly(A) binding	5/2115	26/18639	0.192307692307692	1.69476268412439	0.165366620737561	0.490242329320535
GO:0043548	phosphatidylinositol 3-kinase binding	5/2115	26/18639	0.192307692307692	1.69476268412439	0.165366620737561	0.490242329320535
GO:0070006	metalloaminopeptidase activity	5/2115	26/18639	0.192307692307692	1.69476268412439	0.165366620737561	0.490242329320535
GO:0097110	scaffold protein binding	11/2115	70/18639	0.157142857142857	1.3848632218845	0.16563299145574	0.490242329320535
GO:0015291	secondary active transmembrane transporter activity	38/2115	287/18639	0.132404181184669	1.16684706056787	0.176374593448833	0.517149534951178
GO:0005172	vascular endothelial growth factor receptor binding	3/2115	13/18639	0.230769230769231	2.03371522094926	0.176376079412263	0.517149534951178
GO:0045159	myosin II binding	3/2115	13/18639	0.230769230769231	2.03371522094926	0.176376079412263	0.517149534951178
GO:0070700	BMP receptor binding	3/2115	13/18639	0.230769230769231	2.03371522094926	0.176376079412263	0.517149534951178
GO:0042169	SH2 domain binding	7/2115	41/18639	0.170731707317073	1.50461857810067	0.177386268552617	0.518896280906253
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	6/2115	34/18639	0.176470588235294	1.55519399249061	0.182105316195628	0.529511699052373
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	6/2115	34/18639	0.176470588235294	1.55519399249061	0.182105316195628	0.529511699052373
GO:0004536	DNA nuclease activity	10/2115	64/18639	0.15625	1.37699468085106	0.184948140625504	0.529511699052373
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	4/2115	20/18639	0.2	1.76255319148936	0.184955226982961	0.529511699052373
GO:0010851	cyclase regulator activity	4/2115	20/18639	0.2	1.76255319148936	0.184955226982961	0.529511699052373
GO:0016004	phospholipase activator activity	4/2115	20/18639	0.2	1.76255319148936	0.184955226982961	0.529511699052373
GO:0030742	GTP-dependent protein binding	4/2115	20/18639	0.2	1.76255319148936	0.184955226982961	0.529511699052373
GO:0042288	MHC class I protein binding	4/2115	20/18639	0.2	1.76255319148936	0.184955226982961	0.529511699052373
GO:0052745	inositol phosphate phosphatase activity	4/2115	20/18639	0.2	1.76255319148936	0.184955226982961	0.529511699052373
GO:0008266	poly(U) RNA binding	5/2115	27/18639	0.185185185185185	1.63199369582348	0.185244508134936	0.529511699052373
GO:0004722	protein serine/threonine phosphatase activity	15/2115	103/18639	0.145631067961165	1.28341251807478	0.187646249455516	0.535155135121425
GO:0015297	antiporter activity	19/2115	135/18639	0.140740740740741	1.24031520882585	0.190536687200228	0.541165156891845
GO:0016791	phosphatase activity	36/2115	273/18639	0.131868131868132	1.16212298339958	0.190618078425961	0.541165156891845
GO:0004896	cytokine receptor activity	14/2115	96/18639	0.145833333333333	1.28519503546099	0.196523295906903	0.556667797455753
GO:0016229	steroid dehydrogenase activity	6/2115	35/18639	0.171428571428571	1.51075987841945	0.20017574481764	0.565733707701322
GO:0005126	cytokine receptor binding	36/2115	275/18639	0.130909090909091	1.15367117988395	0.203051042530295	0.570625686657041
GO:0030971	receptor tyrosine kinase binding	12/2115	81/18639	0.148148148148148	1.30559495665879	0.204114223652037	0.570625686657041
GO:0046625	sphingolipid binding	5/2115	28/18639	0.178571428571429	1.57370820668693	0.205933993743682	0.570625686657041
GO:0008474	palmitoyl-(protein) hydrolase activity	3/2115	14/18639	0.214285714285714	1.88844984802432	0.206675545479493	0.570625686657041
GO:0008494	translation activator activity	3/2115	14/18639	0.214285714285714	1.88844984802432	0.206675545479493	0.570625686657041
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	3/2115	14/18639	0.214285714285714	1.88844984802432	0.206675545479493	0.570625686657041
GO:0046030	inositol trisphosphate phosphatase activity	3/2115	14/18639	0.214285714285714	1.88844984802432	0.206675545479493	0.570625686657041
GO:0071933	Arp2/3 complex binding	3/2115	14/18639	0.214285714285714	1.88844984802432	0.206675545479493	0.570625686657041
GO:0098599	palmitoyl hydrolase activity	3/2115	14/18639	0.214285714285714	1.88844984802432	0.206675545479493	0.570625686657041
GO:1901474	azole transmembrane transporter activity	3/2115	14/18639	0.214285714285714	1.88844984802432	0.206675545479493	0.570625686657041
GO:0001846	opsonin binding	4/2115	21/18639	0.19047619047619	1.67862208713273	0.209351092947564	0.570625686657041
GO:0008373	sialyltransferase activity	4/2115	21/18639	0.19047619047619	1.67862208713273	0.209351092947564	0.570625686657041
GO:0015174	basic amino acid transmembrane transporter activity	4/2115	21/18639	0.19047619047619	1.67862208713273	0.209351092947564	0.570625686657041
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	4/2115	21/18639	0.19047619047619	1.67862208713273	0.209351092947564	0.570625686657041
GO:0061891	calcium ion sensor activity	4/2115	21/18639	0.19047619047619	1.67862208713273	0.209351092947564	0.570625686657041
GO:1904047	S-adenosyl-L-methionine binding	4/2115	21/18639	0.19047619047619	1.67862208713273	0.209351092947564	0.570625686657041
GO:0008375	acetylglucosaminyltransferase activity	7/2115	43/18639	0.162790697674419	1.43463631865413	0.210110576317009	0.570625686657041
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	7/2115	43/18639	0.162790697674419	1.43463631865413	0.210110576317009	0.570625686657041
GO:0005319	lipid transporter activity	24/2115	178/18639	0.134831460674157	1.18823810662204	0.213017136361515	0.57726721801865
GO:0048029	monosaccharide binding	11/2115	74/18639	0.148648648648649	1.31000575043128	0.214131730669537	0.579034399132312
GO:0016597	amino acid binding	8/2115	51/18639	0.156862745098039	1.38239465999166	0.216917441557972	0.585303096617631
GO:0044390	ubiquitin-like protein conjugating enzyme binding	6/2115	36/18639	0.166666666666667	1.46879432624113	0.218867979828396	0.589296152140111
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	5/2115	29/18639	0.172413793103448	1.51944240645635	0.227335140146432	0.609472367159172
GO:0106222	lncRNA binding	5/2115	29/18639	0.172413793103448	1.51944240645635	0.227335140146432	0.609472367159172
GO:0019888	protein phosphatase regulator activity	15/2115	107/18639	0.14018691588785	1.23543448001591	0.229654887373578	0.612153913499293
GO:0015377	chloride:monoatomic cation symporter activity	4/2115	22/18639	0.181818181818182	1.60232108317215	0.234585793383915	0.612153913499293
GO:0034062	5'-3' RNA polymerase activity	4/2115	22/18639	0.181818181818182	1.60232108317215	0.234585793383915	0.612153913499293
GO:0097747	RNA polymerase activity	4/2115	22/18639	0.181818181818182	1.60232108317215	0.234585793383915	0.612153913499293
GO:0140784	metal ion sensor activity	4/2115	22/18639	0.181818181818182	1.60232108317215	0.234585793383915	0.612153913499293
GO:0001098	basal transcription machinery binding	9/2115	60/18639	0.15	1.32191489361702	0.236513691119809	0.612153913499293
GO:0001099	basal RNA polymerase II transcription machinery binding	9/2115	60/18639	0.15	1.32191489361702	0.236513691119809	0.612153913499293
GO:0004714	transmembrane receptor protein tyrosine kinase activity	9/2115	60/18639	0.15	1.32191489361702	0.236513691119809	0.612153913499293
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	9/2115	60/18639	0.15	1.32191489361702	0.236513691119809	0.612153913499293
GO:0042393	histone binding	32/2115	247/18639	0.129554655870445	1.1417348608838	0.237542120806177	0.612153913499293
GO:0004467	long-chain fatty acid-CoA ligase activity	3/2115	15/18639	0.2	1.76255319148936	0.238016445543718	0.612153913499293
GO:0005041	low-density lipoprotein particle receptor activity	3/2115	15/18639	0.2	1.76255319148936	0.238016445543718	0.612153913499293
GO:0008242	omega peptidase activity	3/2115	15/18639	0.2	1.76255319148936	0.238016445543718	0.612153913499293
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/2115	15/18639	0.2	1.76255319148936	0.238016445543718	0.612153913499293
GO:0016846	carbon-sulfur lyase activity	3/2115	15/18639	0.2	1.76255319148936	0.238016445543718	0.612153913499293
GO:0017081	chloride channel regulator activity	3/2115	15/18639	0.2	1.76255319148936	0.238016445543718	0.612153913499293
GO:0034483	heparan sulfate sulfotransferase activity	3/2115	15/18639	0.2	1.76255319148936	0.238016445543718	0.612153913499293
GO:0061578	K63-linked deubiquitinase activity	3/2115	15/18639	0.2	1.76255319148936	0.238016445543718	0.612153913499293
GO:0140776	protein-containing complex destabilizing activity	3/2115	15/18639	0.2	1.76255319148936	0.238016445543718	0.612153913499293
GO:0043394	proteoglycan binding	6/2115	37/18639	0.162162162162162	1.42909718228867	0.238114182008112	0.612153913499293
GO:0005548	phospholipid transporter activity	10/2115	68/18639	0.147058823529412	1.29599499374218	0.238907234806625	0.612934135200604
GO:0046915	transition metal ion transmembrane transporter activity	7/2115	45/18639	0.155555555555556	1.37087470449173	0.244857578318493	0.624595383300325
GO:0140303	intramembrane lipid transporter activity	7/2115	45/18639	0.155555555555556	1.37087470449173	0.244857578318493	0.624595383300325
GO:0008509	monoatomic anion transmembrane transporter activity	20/2115	149/18639	0.134228187919463	1.18292160502642	0.24494914792369	0.624595383300325
GO:0005544	calcium-dependent phospholipid binding	8/2115	53/18639	0.150943396226415	1.33022882376556	0.249113682944006	0.630668509397328
GO:0015215	nucleotide transmembrane transporter activity	5/2115	30/18639	0.166666666666667	1.46879432624113	0.249345776478976	0.630668509397328
GO:0033612	receptor serine/threonine kinase binding	5/2115	30/18639	0.166666666666667	1.46879432624113	0.249345776478976	0.630668509397328
GO:0098918	structural constituent of synapse	5/2115	30/18639	0.166666666666667	1.46879432624113	0.249345776478976	0.630668509397328
GO:0043531	ADP binding	6/2115	38/18639	0.157894736842105	1.39148936170213	0.257844623735399	0.650849735719192
GO:0005158	insulin receptor binding	4/2115	23/18639	0.173913043478261	1.53265494912118	0.260491734583251	0.650969364667126
GO:0008171	O-methyltransferase activity	4/2115	23/18639	0.173913043478261	1.53265494912118	0.260491734583251	0.650969364667126
GO:0016493	C-C chemokine receptor activity	4/2115	23/18639	0.173913043478261	1.53265494912118	0.260491734583251	0.650969364667126
GO:0031681	G-protein beta-subunit binding	4/2115	23/18639	0.173913043478261	1.53265494912118	0.260491734583251	0.650969364667126
GO:0043274	phospholipase binding	4/2115	23/18639	0.173913043478261	1.53265494912118	0.260491734583251	0.650969364667126
GO:0030276	clathrin binding	7/2115	46/18639	0.152173913043478	1.34107308048104	0.262864832169949	0.654287812876296
GO:0030291	protein serine/threonine kinase inhibitor activity	7/2115	46/18639	0.152173913043478	1.34107308048104	0.262864832169949	0.654287812876296
GO:0003712	transcription coregulator activity	61/2115	495/18639	0.123232323232323	1.0860176230389	0.263418547432328	0.654365121796181
GO:0015485	cholesterol binding	8/2115	54/18639	0.148148148148148	1.30559495665879	0.265758366420481	0.65518628540166
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	8/2115	54/18639	0.148148148148148	1.30559495665879	0.265758366420481	0.65518628540166
GO:0050661	NADP binding	8/2115	54/18639	0.148148148148148	1.30559495665879	0.265758366420481	0.65518628540166
GO:0035173	histone kinase activity	45/2115	360/18639	0.125	1.10159574468085	0.265842358613453	0.65518628540166
GO:0046982	protein heterodimerization activity	46/2115	369/18639	0.124661246612466	1.09861039035922	0.269395481066374	0.655305806022776
GO:0005149	interleukin-1 receptor binding	3/2115	16/18639	0.1875	1.65239361702128	0.270078111747406	0.655305806022776
GO:0005521	lamin binding	3/2115	16/18639	0.1875	1.65239361702128	0.270078111747406	0.655305806022776
GO:0022858	alanine transmembrane transporter activity	3/2115	16/18639	0.1875	1.65239361702128	0.270078111747406	0.655305806022776
GO:0030275	LRR domain binding	3/2115	16/18639	0.1875	1.65239361702128	0.270078111747406	0.655305806022776
GO:0034450	ubiquitin-ubiquitin ligase activity	3/2115	16/18639	0.1875	1.65239361702128	0.270078111747406	0.655305806022776
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	3/2115	16/18639	0.1875	1.65239361702128	0.270078111747406	0.655305806022776
GO:0140327	flippase activity	3/2115	16/18639	0.1875	1.65239361702128	0.270078111747406	0.655305806022776
GO:0005164	tumor necrosis factor receptor binding	5/2115	31/18639	0.161290322580645	1.42141386410432	0.271863013104593	0.657089753681372
GO:0017147	Wnt-protein binding	5/2115	31/18639	0.161290322580645	1.42141386410432	0.271863013104593	0.657089753681372
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	6/2115	39/18639	0.153846153846154	1.35581014729951	0.277988521031119	0.670600439944047
GO:0008081	phosphoric diester hydrolase activity	12/2115	87/18639	0.137931034482759	1.21555392516508	0.280442829914427	0.675220044332428
GO:0141003	histone H2AX kinase activity	44/2115	354/18639	0.124293785310734	1.09537203990864	0.281701509664692	0.675764597627633
GO:0033293	monocarboxylic acid binding	11/2115	79/18639	0.139240506329114	1.22709399407487	0.281748498371905	0.675764597627633
GO:0140313	molecular sequestering activity	8/2115	55/18639	0.145454545454545	1.28185686653772	0.282713974745165	0.676783740690145
GO:0019957	C-C chemokine binding	4/2115	24/18639	0.166666666666667	1.46879432624113	0.286905260228895	0.679027194341354
GO:0042625	ATPase-coupled ion transmembrane transporter activity	4/2115	24/18639	0.166666666666667	1.46879432624113	0.286905260228895	0.679027194341354
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	4/2115	24/18639	0.166666666666667	1.46879432624113	0.286905260228895	0.679027194341354
GO:0046961	proton-transporting ATPase activity, rotational mechanism	4/2115	24/18639	0.166666666666667	1.46879432624113	0.286905260228895	0.679027194341354
GO:0060229	lipase activator activity	4/2115	24/18639	0.166666666666667	1.46879432624113	0.286905260228895	0.679027194341354
GO:0070300	phosphatidic acid binding	4/2115	24/18639	0.166666666666667	1.46879432624113	0.286905260228895	0.679027194341354
GO:0016407	acetyltransferase activity	13/2115	96/18639	0.135416666666667	1.19339539007092	0.291760059874469	0.685184246878784
GO:0003714	transcription corepressor activity	26/2115	204/18639	0.127450980392157	1.12319566124322	0.293835938162121	0.685184246878784
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	5/2115	32/18639	0.15625	1.37699468085106	0.294784596942156	0.685184246878784
GO:0071813	lipoprotein particle binding	5/2115	32/18639	0.15625	1.37699468085106	0.294784596942156	0.685184246878784
GO:0071814	protein-lipid complex binding	5/2115	32/18639	0.15625	1.37699468085106	0.294784596942156	0.685184246878784
GO:0030246	carbohydrate binding	35/2115	280/18639	0.125	1.10159574468085	0.296276132846692	0.685184246878784
GO:0050997	quaternary ammonium group binding	6/2115	40/18639	0.15	1.32191489361702	0.298474807245295	0.685184246878784
GO:0170055	lipid transmembrane transporter activity	8/2115	56/18639	0.142857142857143	1.25896656534954	0.299939551529539	0.685184246878784
GO:0140996	histone H3 kinase activity	44/2115	357/18639	0.123249299719888	1.08616723285059	0.301757709901044	0.685184246878784
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	3/2115	17/18639	0.176470588235294	1.55519399249061	0.302564525364307	0.685184246878784
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/2115	17/18639	0.176470588235294	1.55519399249061	0.302564525364307	0.685184246878784
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	3/2115	17/18639	0.176470588235294	1.55519399249061	0.302564525364307	0.685184246878784
GO:0019198	transmembrane receptor protein phosphatase activity	3/2115	17/18639	0.176470588235294	1.55519399249061	0.302564525364307	0.685184246878784
GO:0030169	low-density lipoprotein particle binding	3/2115	17/18639	0.176470588235294	1.55519399249061	0.302564525364307	0.685184246878784
GO:0031489	myosin V binding	3/2115	17/18639	0.176470588235294	1.55519399249061	0.302564525364307	0.685184246878784
GO:0048038	quinone binding	3/2115	17/18639	0.176470588235294	1.55519399249061	0.302564525364307	0.685184246878784
GO:0051787	misfolded protein binding	3/2115	17/18639	0.176470588235294	1.55519399249061	0.302564525364307	0.685184246878784
GO:0070402	NADPH binding	3/2115	17/18639	0.176470588235294	1.55519399249061	0.302564525364307	0.685184246878784
GO:0070403	NAD+ binding	3/2115	17/18639	0.176470588235294	1.55519399249061	0.302564525364307	0.685184246878784
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	16/2115	122/18639	0.131147540983607	1.15577258458319	0.307697876102607	0.685184246878784
GO:0030295	protein kinase activator activity	18/2115	139/18639	0.129496402877698	1.14122149089239	0.311989375239438	0.685184246878784
GO:0043539	protein serine/threonine kinase activator activity	10/2115	73/18639	0.136986301369863	1.20722821334888	0.313039506692099	0.685184246878784
GO:0003707	nuclear steroid receptor activity	4/2115	25/18639	0.16	1.41004255319149	0.313668858080441	0.685184246878784
GO:0004709	MAP kinase kinase kinase activity	4/2115	25/18639	0.16	1.41004255319149	0.313668858080441	0.685184246878784
GO:0015296	monoatomic anion:monoatomic cation symporter activity	4/2115	25/18639	0.16	1.41004255319149	0.313668858080441	0.685184246878784
GO:0015662	P-type ion transporter activity	4/2115	25/18639	0.16	1.41004255319149	0.313668858080441	0.685184246878784
GO:0042974	nuclear retinoic acid receptor binding	4/2115	25/18639	0.16	1.41004255319149	0.313668858080441	0.685184246878784
GO:0140358	P-type transmembrane transporter activity	4/2115	25/18639	0.16	1.41004255319149	0.313668858080441	0.685184246878784
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	23/2115	181/18639	0.12707182320442	1.11985423768661	0.313776120527228	0.685184246878784
GO:0008013	beta-catenin binding	14/2115	106/18639	0.132075471698113	1.16395022079486	0.314567274239348	0.685184246878784
GO:0017171	serine hydrolase activity	25/2115	198/18639	0.126262626262626	1.1127229744251	0.315561037477874	0.685184246878784
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0004935	adrenergic receptor activity	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0004955	prostaglandin receptor activity	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0005337	nucleoside transmembrane transporter activity	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0015203	polyamine transmembrane transporter activity	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0016303	1-phosphatidylinositol-3-kinase activity	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0031419	cobalamin binding	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0032356	oxidized DNA binding	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0033204	ribonuclease P RNA binding	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0043121	neurotrophin binding	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0098505	G-rich strand telomeric DNA binding	2/2115	10/18639	0.2	1.76255319148936	0.316323078830621	0.685184246878784
GO:0015932	nucleobase-containing compound transmembrane transporter activity	8/2115	57/18639	0.140350877192982	1.23687943262411	0.317393820983149	0.685556635929833
GO:0030296	protein tyrosine kinase activator activity	5/2115	33/18639	0.151515151515152	1.33526756931012	0.318010103076914	0.685556635929833
GO:0001222	transcription corepressor binding	7/2115	49/18639	0.142857142857143	1.25896656534954	0.318795022312785	0.685556635929833
GO:0001530	lipopolysaccharide binding	6/2115	41/18639	0.146341463414634	1.28967306694344	0.319232842449754	0.685556635929833
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	6/2115	41/18639	0.146341463414634	1.28967306694344	0.319232842449754	0.685556635929833
GO:1901681	sulfur compound binding	34/2115	275/18639	0.123636363636364	1.08957833655706	0.323180929128279	0.692846786418845
GO:0004706	JUN kinase kinase kinase activity	3/2115	18/18639	0.166666666666667	1.46879432624113	0.335206782586429	0.705342675291107
GO:0008308	voltage-gated monoatomic anion channel activity	3/2115	18/18639	0.166666666666667	1.46879432624113	0.335206782586429	0.705342675291107
GO:0008409	5'-3' exonuclease activity	3/2115	18/18639	0.166666666666667	1.46879432624113	0.335206782586429	0.705342675291107
GO:0015172	acidic amino acid transmembrane transporter activity	3/2115	18/18639	0.166666666666667	1.46879432624113	0.335206782586429	0.705342675291107
GO:0017075	syntaxin-1 binding	3/2115	18/18639	0.166666666666667	1.46879432624113	0.335206782586429	0.705342675291107
GO:0017128	phospholipid scramblase activity	3/2115	18/18639	0.166666666666667	1.46879432624113	0.335206782586429	0.705342675291107
GO:0034185	apolipoprotein binding	3/2115	18/18639	0.166666666666667	1.46879432624113	0.335206782586429	0.705342675291107
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	3/2115	18/18639	0.166666666666667	1.46879432624113	0.335206782586429	0.705342675291107
GO:0070628	proteasome binding	3/2115	18/18639	0.166666666666667	1.46879432624113	0.335206782586429	0.705342675291107
GO:0099602	neurotransmitter receptor regulator activity	3/2115	18/18639	0.166666666666667	1.46879432624113	0.335206782586429	0.705342675291107
GO:1901611	phosphatidylglycerol binding	3/2115	18/18639	0.166666666666667	1.46879432624113	0.335206782586429	0.705342675291107
GO:0015605	organophosphate ester transmembrane transporter activity	7/2115	50/18639	0.14	1.23378723404255	0.337898784582532	0.708425900904621
GO:0008307	structural constituent of muscle	6/2115	42/18639	0.142857142857143	1.25896656534954	0.340193054631977	0.708425900904621
GO:0001637	G protein-coupled chemoattractant receptor activity	4/2115	26/18639	0.153846153846154	1.35581014729951	0.340632901233692	0.708425900904621
GO:0004950	chemokine receptor activity	4/2115	26/18639	0.153846153846154	1.35581014729951	0.340632901233692	0.708425900904621
GO:0050681	nuclear androgen receptor binding	4/2115	26/18639	0.153846153846154	1.35581014729951	0.340632901233692	0.708425900904621
GO:0070412	R-SMAD binding	4/2115	26/18639	0.153846153846154	1.35581014729951	0.340632901233692	0.708425900904621
GO:0097602	cullin family protein binding	4/2115	26/18639	0.153846153846154	1.35581014729951	0.340632901233692	0.708425900904621
GO:0043178	alcohol binding	12/2115	92/18639	0.130434782608696	1.14949121184089	0.349686364356171	0.71943879324373
GO:0008236	serine-type peptidase activity	24/2115	194/18639	0.123711340206186	1.09023908751919	0.358113297628459	0.71943879324373
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0002162	dystroglycan binding	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0004954	prostanoid receptor activity	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0005225	volume-sensitive anion channel activity	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0008271	secondary active sulfate transmembrane transporter activity	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0008526	phosphatidylinositol transfer activity	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0015217	ADP transmembrane transporter activity	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0031731	CCR6 chemokine receptor binding	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0032050	clathrin heavy chain binding	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0032794	GTPase activating protein binding	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0034713	type I transforming growth factor beta receptor binding	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0042608	T cell receptor binding	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0043522	leucine zipper domain binding	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0050998	nitric-oxide synthase binding	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0070697	activin receptor binding	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0099528	G protein-coupled neurotransmitter receptor activity	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0140031	phosphorylation-dependent protein binding	2/2115	11/18639	0.181818181818182	1.60232108317215	0.359888183309909	0.71943879324373
GO:0140566	histone reader activity	5/2115	35/18639	0.142857142857143	1.25896656534954	0.364986332561764	0.71943879324373
GO:0032934	sterol binding	9/2115	68/18639	0.132352941176471	1.16639549436796	0.365159912021047	0.71943879324373
GO:0005385	zinc ion transmembrane transporter activity	4/2115	27/18639	0.148148148148148	1.30559495665879	0.367656969598692	0.71943879324373
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/2115	27/18639	0.148148148148148	1.30559495665879	0.367656969598692	0.71943879324373
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	4/2115	27/18639	0.148148148148148	1.30559495665879	0.367656969598692	0.71943879324373
GO:0035255	ionotropic glutamate receptor binding	4/2115	27/18639	0.148148148148148	1.30559495665879	0.367656969598692	0.71943879324373
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	4/2115	27/18639	0.148148148148148	1.30559495665879	0.367656969598692	0.71943879324373
GO:0042826	histone deacetylase binding	16/2115	127/18639	0.125984251968504	1.11026972692243	0.367717625799641	0.71943879324373
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	3/2115	19/18639	0.157894736842105	1.39148936170213	0.367764239357817	0.71943879324373
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/2115	19/18639	0.157894736842105	1.39148936170213	0.367764239357817	0.71943879324373
GO:0016918	retinal binding	3/2115	19/18639	0.157894736842105	1.39148936170213	0.367764239357817	0.71943879324373
GO:0022840	leak channel activity	3/2115	19/18639	0.157894736842105	1.39148936170213	0.367764239357817	0.71943879324373
GO:0022842	narrow pore channel activity	3/2115	19/18639	0.157894736842105	1.39148936170213	0.367764239357817	0.71943879324373
GO:0031420	alkali metal ion binding	3/2115	19/18639	0.157894736842105	1.39148936170213	0.367764239357817	0.71943879324373
GO:0070003	threonine-type peptidase activity	3/2115	19/18639	0.157894736842105	1.39148936170213	0.367764239357817	0.71943879324373
GO:0097001	ceramide binding	3/2115	19/18639	0.157894736842105	1.39148936170213	0.367764239357817	0.71943879324373
GO:0008238	exopeptidase activity	13/2115	102/18639	0.127450980392157	1.12319566124322	0.372131814183325	0.726847162804248
GO:0016779	nucleotidyltransferase activity	17/2115	136/18639	0.125	1.10159574468085	0.374046241039829	0.729448432682034
GO:0002039	p53 binding	9/2115	69/18639	0.130434782608696	1.14949121184089	0.381950206003617	0.739753636278625
GO:0016790	thiolester hydrolase activity	6/2115	44/18639	0.136363636363636	1.20174081237911	0.382450415855457	0.739753636278625
GO:0030547	signaling receptor inhibitor activity	6/2115	44/18639	0.136363636363636	1.20174081237911	0.382450415855457	0.739753636278625
GO:0050660	flavin adenine dinucleotide binding	11/2115	86/18639	0.127906976744186	1.1272142503711	0.384651656654216	0.739753636278625
GO:0005506	iron ion binding	19/2115	154/18639	0.123376623376623	1.08728930643824	0.385305686730762	0.739753636278625
GO:0045505	dynein intermediate chain binding	5/2115	36/18639	0.138888888888889	1.22399527186761	0.388553808809082	0.739753636278625
GO:0016836	hydro-lyase activity	8/2115	61/18639	0.131147540983607	1.15577258458319	0.388677139431043	0.739753636278625
GO:0019905	syntaxin binding	8/2115	61/18639	0.131147540983607	1.15577258458319	0.388677139431043	0.739753636278625
GO:0050698	proteoglycan sulfotransferase activity	4/2115	28/18639	0.142857142857143	1.25896656534954	0.394610798907861	0.739753636278625
GO:0051393	alpha-actinin binding	4/2115	28/18639	0.142857142857143	1.25896656534954	0.394610798907861	0.739753636278625
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	4/2115	28/18639	0.142857142857143	1.25896656534954	0.394610798907861	0.739753636278625
GO:0005003	ephrin receptor activity	7/2115	53/18639	0.132075471698113	1.16395022079486	0.395867993709551	0.739753636278625
GO:0005005	transmembrane-ephrin receptor activity	7/2115	53/18639	0.132075471698113	1.16395022079486	0.395867993709551	0.739753636278625
GO:0005246	calcium channel regulator activity	7/2115	53/18639	0.132075471698113	1.16395022079486	0.395867993709551	0.739753636278625
GO:0017046	peptide hormone binding	7/2115	53/18639	0.132075471698113	1.16395022079486	0.395867993709551	0.739753636278625
GO:0005326	neurotransmitter transmembrane transporter activity	3/2115	20/18639	0.15	1.32191489361702	0.40002465330632	0.739753636278625
GO:0015095	magnesium ion transmembrane transporter activity	3/2115	20/18639	0.15	1.32191489361702	0.40002465330632	0.739753636278625
GO:0016505	peptidase activator activity involved in apoptotic process	3/2115	20/18639	0.15	1.32191489361702	0.40002465330632	0.739753636278625
GO:0140664	ATP-dependent DNA damage sensor activity	3/2115	20/18639	0.15	1.32191489361702	0.40002465330632	0.739753636278625
GO:0000340	RNA 7-methylguanosine cap binding	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0003720	telomerase activity	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0004126	cytidine deaminase activity	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0004526	ribonuclease P activity	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0004875	complement receptor activity	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0005049	nuclear export signal receptor activity	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0005095	GTPase inhibitor activity	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0008179	adenylate cyclase binding	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0008504	monoamine transmembrane transporter activity	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0015132	prostaglandin transmembrane transporter activity	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0015269	calcium-activated potassium channel activity	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0016208	AMP binding	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0016423	tRNA (guanine) methyltransferase activity	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0031543	peptidyl-proline dioxygenase activity	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0035197	siRNA binding	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0043047	single-stranded telomeric DNA binding	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0097677	STAT family protein binding	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:1990459	transferrin receptor binding	2/2115	12/18639	0.166666666666667	1.46879432624113	0.402373982672319	0.739753636278625
GO:0005539	glycosaminoglycan binding	29/2115	242/18639	0.119834710743802	1.05607525936346	0.406520877782096	0.746281728714347
GO:0070851	growth factor receptor binding	17/2115	139/18639	0.122302158273381	1.07782029695393	0.409830427126389	0.751255775640175
GO:0042805	actinin binding	5/2115	37/18639	0.135135135135135	1.19091431857389	0.412060000496733	0.754238480441389
GO:0019209	kinase activator activity	18/2115	148/18639	0.121621621621622	1.0718228867165	0.414654169889647	0.757854258278217
GO:0140463	chromatin-protein adaptor activity	7/2115	54/18639	0.12962962962963	1.14239558707644	0.415246023305796	0.757854258278217
GO:0003924	GTPase activity	39/2115	331/18639	0.117824773413897	1.03836215208588	0.426372940332724	0.777028997520481
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	16/2115	132/18639	0.121212121212121	1.0682140554481	0.429369723713603	0.781353043734638
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/2115	21/18639	0.142857142857143	1.25896656534954	0.431803580032781	0.78237059652828
GO:0035613	RNA stem-loop binding	3/2115	21/18639	0.142857142857143	1.25896656534954	0.431803580032781	0.78237059652828
GO:0072542	protein phosphatase activator activity	3/2115	21/18639	0.142857142857143	1.25896656534954	0.431803580032781	0.78237059652828
GO:0042626	ATPase-coupled transmembrane transporter activity	12/2115	98/18639	0.122448979591837	1.07911419887104	0.43583278158332	0.788529830263463
GO:0003964	RNA-directed DNA polymerase activity	2/2115	13/18639	0.153846153846154	1.35581014729951	0.443464510537783	0.788661317035944
GO:0009982	pseudouridine synthase activity	2/2115	13/18639	0.153846153846154	1.35581014729951	0.443464510537783	0.788661317035944
GO:0015651	quaternary ammonium group transmembrane transporter activity	2/2115	13/18639	0.153846153846154	1.35581014729951	0.443464510537783	0.788661317035944
GO:0030955	potassium ion binding	2/2115	13/18639	0.153846153846154	1.35581014729951	0.443464510537783	0.788661317035944
GO:0031432	titin binding	2/2115	13/18639	0.153846153846154	1.35581014729951	0.443464510537783	0.788661317035944
GO:0035325	Toll-like receptor binding	2/2115	13/18639	0.153846153846154	1.35581014729951	0.443464510537783	0.788661317035944
GO:0046974	histone H3K9 methyltransferase activity	2/2115	13/18639	0.153846153846154	1.35581014729951	0.443464510537783	0.788661317035944
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/2115	13/18639	0.153846153846154	1.35581014729951	0.443464510537783	0.788661317035944
GO:0071714	icosanoid transmembrane transporter activity	2/2115	13/18639	0.153846153846154	1.35581014729951	0.443464510537783	0.788661317035944
GO:0071837	HMG box domain binding	2/2115	13/18639	0.153846153846154	1.35581014729951	0.443464510537783	0.788661317035944
GO:0140333	glycerophospholipid flippase activity	2/2115	13/18639	0.153846153846154	1.35581014729951	0.443464510537783	0.788661317035944
GO:1901338	catecholamine binding	2/2115	13/18639	0.153846153846154	1.35581014729951	0.443464510537783	0.788661317035944
GO:0001965	G-protein alpha-subunit binding	4/2115	30/18639	0.133333333333333	1.17503546099291	0.447840923975954	0.791181427282042
GO:0016769	transferase activity, transferring nitrogenous groups	4/2115	30/18639	0.133333333333333	1.17503546099291	0.447840923975954	0.791181427282042
GO:0031210	phosphatidylcholine binding	4/2115	30/18639	0.133333333333333	1.17503546099291	0.447840923975954	0.791181427282042
GO:0031624	ubiquitin conjugating enzyme binding	4/2115	30/18639	0.133333333333333	1.17503546099291	0.447840923975954	0.791181427282042
GO:0001216	DNA-binding transcription activator activity	57/2115	491/18639	0.116089613034623	1.0230705897647	0.44804123957106	0.791181427282042
GO:0005496	steroid binding	13/2115	108/18639	0.12037037037037	1.06079590228526	0.454885902690616	0.802136831223452
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	56/2115	484/18639	0.115702479338843	1.01965887110955	0.459462624571755	0.809067800230432
GO:0008093	cytoskeletal anchor activity	3/2115	22/18639	0.136363636363636	1.20174081237911	0.462943230556286	0.810636258260797
GO:0008649	rRNA methyltransferase activity	3/2115	22/18639	0.136363636363636	1.20174081237911	0.462943230556286	0.810636258260797
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/2115	22/18639	0.136363636363636	1.20174081237911	0.462943230556286	0.810636258260797
GO:0033691	sialic acid binding	3/2115	22/18639	0.136363636363636	1.20174081237911	0.462943230556286	0.810636258260797
GO:0043130	ubiquitin binding	12/2115	100/18639	0.12	1.05753191489362	0.464601437730768	0.812403631339276
GO:0030165	PDZ domain binding	10/2115	83/18639	0.120481927710843	1.06177903101769	0.470840401290544	0.822164829031745
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/2115	31/18639	0.129032258064516	1.13713109128346	0.473911725586525	0.822936866067031
GO:0008327	methyl-CpG binding	4/2115	31/18639	0.129032258064516	1.13713109128346	0.473911725586525	0.822936866067031
GO:0047499	calcium-independent phospholipase A2 activity	4/2115	31/18639	0.129032258064516	1.13713109128346	0.473911725586525	0.822936866067031
GO:0070325	lipoprotein particle receptor binding	4/2115	31/18639	0.129032258064516	1.13713109128346	0.473911725586525	0.822936866067031
GO:0052689	carboxylic ester hydrolase activity	11/2115	92/18639	0.119565217391304	1.05370027752081	0.475101227239411	0.823859745850059
GO:0019003	GDP binding	9/2115	75/18639	0.12	1.05753191489362	0.482630201590363	0.824470378123451
GO:0004705	JUN kinase activity	2/2115	14/18639	0.142857142857143	1.25896656534954	0.482929338047499	0.824470378123451
GO:0005313	L-glutamate transmembrane transporter activity	2/2115	14/18639	0.142857142857143	1.25896656534954	0.482929338047499	0.824470378123451
GO:0005347	ATP transmembrane transporter activity	2/2115	14/18639	0.142857142857143	1.25896656534954	0.482929338047499	0.824470378123451
GO:0008191	metalloendopeptidase inhibitor activity	2/2115	14/18639	0.142857142857143	1.25896656534954	0.482929338047499	0.824470378123451
GO:0008559	ABC-type xenobiotic transporter activity	2/2115	14/18639	0.142857142857143	1.25896656534954	0.482929338047499	0.824470378123451
GO:0016530	metallochaperone activity	2/2115	14/18639	0.142857142857143	1.25896656534954	0.482929338047499	0.824470378123451
GO:0019992	diacylglycerol binding	2/2115	14/18639	0.142857142857143	1.25896656534954	0.482929338047499	0.824470378123451
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	2/2115	14/18639	0.142857142857143	1.25896656534954	0.482929338047499	0.824470378123451
GO:0043176	amine binding	2/2115	14/18639	0.142857142857143	1.25896656534954	0.482929338047499	0.824470378123451
GO:0098847	sequence-specific single stranded DNA binding	2/2115	14/18639	0.142857142857143	1.25896656534954	0.482929338047499	0.824470378123451
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	31/2115	268/18639	0.115671641791045	1.0193871070181	0.483355637014867	0.824470378123451
GO:0016763	pentosyltransferase activity	6/2115	49/18639	0.122448979591837	1.07911419887104	0.487187123116291	0.828747660518472
GO:0035254	glutamate receptor binding	6/2115	49/18639	0.122448979591837	1.07911419887104	0.487187123116291	0.828747660518472
GO:0008201	heparin binding	20/2115	172/18639	0.116279069767442	1.02474022761009	0.489383700299792	0.831354671336961
GO:0000295	adenine nucleotide transmembrane transporter activity	3/2115	23/18639	0.130434782608696	1.14949121184089	0.493310954952241	0.834628804865142
GO:0140102	catalytic activity, acting on a rRNA	3/2115	23/18639	0.130434782608696	1.14949121184089	0.493310954952241	0.834628804865142
GO:0140103	catalytic activity, acting on a glycoprotein	3/2115	23/18639	0.130434782608696	1.14949121184089	0.493310954952241	0.834628804865142
GO:1902936	phosphatidylinositol bisphosphate binding	13/2115	111/18639	0.117117117117117	1.03212574276404	0.496003475172434	0.83805175562198
GO:0015106	bicarbonate transmembrane transporter activity	4/2115	32/18639	0.125	1.10159574468085	0.499501315392864	0.839430398485726
GO:0042910	xenobiotic transmembrane transporter activity	4/2115	32/18639	0.125	1.10159574468085	0.499501315392864	0.839430398485726
GO:0047498	calcium-dependent phospholipase A2 activity	4/2115	32/18639	0.125	1.10159574468085	0.499501315392864	0.839430398485726
GO:0140142	nucleocytoplasmic carrier activity	4/2115	32/18639	0.125	1.10159574468085	0.499501315392864	0.839430398485726
GO:0042287	MHC protein binding	5/2115	41/18639	0.121951219512195	1.0747275557862	0.503980722148798	0.84388561624097
GO:0140828	metal cation:monoatomic cation antiporter activity	5/2115	41/18639	0.121951219512195	1.0747275557862	0.503980722148798	0.84388561624097
GO:0016410	N-acyltransferase activity	11/2115	94/18639	0.117021276595745	1.03128112267995	0.504833098827394	0.84388561624097
GO:0140375	immune receptor activity	18/2115	156/18639	0.115384615384615	1.01685761047463	0.507480311137472	0.84388561624097
GO:0005007	fibroblast growth factor receptor activity	6/2115	50/18639	0.12	1.05753191489362	0.50754462382544	0.84388561624097
GO:0005017	platelet-derived growth factor receptor activity	6/2115	50/18639	0.12	1.05753191489362	0.50754462382544	0.84388561624097
GO:0005019	platelet-derived growth factor beta-receptor activity	6/2115	50/18639	0.12	1.05753191489362	0.50754462382544	0.84388561624097
GO:0032813	tumor necrosis factor receptor superfamily binding	6/2115	50/18639	0.12	1.05753191489362	0.50754462382544	0.84388561624097
GO:0005096	GTPase activator activity	31/2115	271/18639	0.114391143911439	1.00810237889613	0.509641191518564	0.8443810906097
GO:0001786	phosphatidylserine binding	7/2115	59/18639	0.11864406779661	1.04558240173098	0.510540323954906	0.8443810906097
GO:0015459	potassium channel regulator activity	7/2115	59/18639	0.11864406779661	1.04558240173098	0.510540323954906	0.8443810906097
GO:0070888	E-box binding	7/2115	59/18639	0.11864406779661	1.04558240173098	0.510540323954906	0.8443810906097
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	15/2115	130/18639	0.115384615384615	1.01685761047463	0.513644811114596	0.84566207807218
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/2115	15/18639	0.133333333333333	1.17503546099291	0.520608244586542	0.84566207807218
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/2115	15/18639	0.133333333333333	1.17503546099291	0.520608244586542	0.84566207807218
GO:0004953	icosanoid receptor activity	2/2115	15/18639	0.133333333333333	1.17503546099291	0.520608244586542	0.84566207807218
GO:0005523	tropomyosin binding	2/2115	15/18639	0.133333333333333	1.17503546099291	0.520608244586542	0.84566207807218
GO:0015116	sulfate transmembrane transporter activity	2/2115	15/18639	0.133333333333333	1.17503546099291	0.520608244586542	0.84566207807218
GO:0033130	acetylcholine receptor binding	2/2115	15/18639	0.133333333333333	1.17503546099291	0.520608244586542	0.84566207807218
GO:0047372	monoacylglycerol lipase activity	2/2115	15/18639	0.133333333333333	1.17503546099291	0.520608244586542	0.84566207807218
GO:0048531	beta-1,3-galactosyltransferase activity	2/2115	15/18639	0.133333333333333	1.17503546099291	0.520608244586542	0.84566207807218
GO:0120283	protein serine/threonine kinase binding	2/2115	15/18639	0.133333333333333	1.17503546099291	0.520608244586542	0.84566207807218
GO:0015295	solute:proton symporter activity	3/2115	24/18639	0.125	1.10159574468085	0.522797482769862	0.84566207807218
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/2115	24/18639	0.125	1.10159574468085	0.522797482769862	0.84566207807218
GO:0030215	semaphorin receptor binding	3/2115	24/18639	0.125	1.10159574468085	0.522797482769862	0.84566207807218
GO:0035035	histone acetyltransferase binding	3/2115	24/18639	0.125	1.10159574468085	0.522797482769862	0.84566207807218
GO:0050431	transforming growth factor beta binding	3/2115	24/18639	0.125	1.10159574468085	0.522797482769862	0.84566207807218
GO:0070840	dynein complex binding	3/2115	24/18639	0.125	1.10159574468085	0.522797482769862	0.84566207807218
GO:0140612	DNA damage sensor activity	3/2115	24/18639	0.125	1.10159574468085	0.522797482769862	0.84566207807218
GO:0008237	metallopeptidase activity	21/2115	184/18639	0.114130434782609	1.00580481036078	0.523486626158998	0.845684201227181
GO:0071889	14-3-3 protein binding	4/2115	33/18639	0.121212121212121	1.0682140554481	0.524534586057133	0.846285182659189
GO:0048487	beta-tubulin binding	5/2115	42/18639	0.119047619047619	1.04913880445795	0.526114190732152	0.847741270008565
GO:0004713	protein tyrosine kinase activity	16/2115	140/18639	0.114285714285714	1.00717325227964	0.527587609488537	0.849022734035538
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	7/2115	60/18639	0.116666666666667	1.02815602836879	0.529007515130092	0.850214902365693
GO:0008080	N-acetyltransferase activity	8/2115	69/18639	0.115942028985507	1.02176996608079	0.530355152893406	0.851288014644288
GO:0019199	transmembrane receptor protein kinase activity	9/2115	78/18639	0.115384615384615	1.01685761047463	0.531648713987347	0.852271690028372
GO:0004252	serine-type endopeptidase activity	20/2115	176/18639	0.113636363636364	1.00145067698259	0.532801358206306	0.853027238458177
GO:1901981	phosphatidylinositol phosphate binding	21/2115	185/18639	0.113513513513514	1.00036802760207	0.533992434694365	0.853842309370811
GO:0005179	hormone activity	15/2115	132/18639	0.113636363636364	1.00145067698259	0.538551029639136	0.860033021821681
GO:0016247	channel regulator activity	19/2115	168/18639	0.113095238095238	0.996681864235056	0.542560404487496	0.861076175502569
GO:0008186	ATP-dependent activity, acting on RNA	9/2115	79/18639	0.113924050632911	1.00398599515217	0.547625180069145	0.861076175502569
GO:0046332	SMAD binding	9/2115	79/18639	0.113924050632911	1.00398599515217	0.547625180069145	0.861076175502569
GO:0048156	tau protein binding	5/2115	43/18639	0.116279069767442	1.02474022761009	0.547801911805469	0.861076175502569
GO:0019001	guanyl nucleotide binding	45/2115	400/18639	0.1125	0.991436170212766	0.548640252565564	0.861076175502569
GO:0032561	guanyl ribonucleotide binding	45/2115	400/18639	0.1125	0.991436170212766	0.548640252565564	0.861076175502569
GO:0008376	acetylgalactosaminyltransferase activity	4/2115	34/18639	0.117647058823529	1.03679599499374	0.548946935813546	0.861076175502569
GO:0052866	phosphatidylinositol phosphate phosphatase activity	4/2115	34/18639	0.117647058823529	1.03679599499374	0.548946935813546	0.861076175502569
GO:0000149	SNARE binding	12/2115	106/18639	0.113207547169811	0.997671617824167	0.549046782400352	0.861076175502569
GO:0001848	complement binding	3/2115	25/18639	0.12	1.05753191489362	0.551315022500237	0.861076175502569
GO:0008483	transaminase activity	3/2115	25/18639	0.12	1.05753191489362	0.551315022500237	0.861076175502569
GO:0015645	fatty acid ligase activity	3/2115	25/18639	0.12	1.05753191489362	0.551315022500237	0.861076175502569
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/2115	25/18639	0.12	1.05753191489362	0.551315022500237	0.861076175502569
GO:0019211	phosphatase activator activity	3/2115	25/18639	0.12	1.05753191489362	0.551315022500237	0.861076175502569
GO:0120020	cholesterol transfer activity	3/2115	25/18639	0.12	1.05753191489362	0.551315022500237	0.861076175502569
GO:0120515	fatty acid-CoA ligase activity	3/2115	25/18639	0.12	1.05753191489362	0.551315022500237	0.861076175502569
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/2115	16/18639	0.125	1.10159574468085	0.556398263563561	0.861076175502569
GO:0004707	MAP kinase activity	2/2115	16/18639	0.125	1.10159574468085	0.556398263563561	0.861076175502569
GO:0004708	MAP kinase kinase activity	2/2115	16/18639	0.125	1.10159574468085	0.556398263563561	0.861076175502569
GO:0008296	3'-5'-DNA exonuclease activity	2/2115	16/18639	0.125	1.10159574468085	0.556398263563561	0.861076175502569
GO:0016722	oxidoreductase activity, acting on metal ions	2/2115	16/18639	0.125	1.10159574468085	0.556398263563561	0.861076175502569
GO:0022841	potassium ion leak channel activity	2/2115	16/18639	0.125	1.10159574468085	0.556398263563561	0.861076175502569
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/2115	16/18639	0.125	1.10159574468085	0.556398263563561	0.861076175502569
GO:0070411	I-SMAD binding	2/2115	16/18639	0.125	1.10159574468085	0.556398263563561	0.861076175502569
GO:0140328	floppase activity	2/2115	16/18639	0.125	1.10159574468085	0.556398263563561	0.861076175502569
GO:0000049	tRNA binding	9/2115	80/18639	0.1125	0.991436170212766	0.56338470005752	0.870811906755574
GO:0141108	transporter regulator activity	19/2115	170/18639	0.111764705882353	0.984956195244055	0.564300245915415	0.87115155103095
GO:0034212	protein N-acetyltransferase activity	6/2115	53/18639	0.113207547169811	0.997671617824167	0.566640899387978	0.871541039353499
GO:0140296	general transcription initiation factor binding	6/2115	53/18639	0.113207547169811	0.997671617824167	0.566640899387978	0.871541039353499
GO:1901505	carbohydrate derivative transmembrane transporter activity	6/2115	53/18639	0.113207547169811	0.997671617824167	0.566640899387978	0.871541039353499
GO:0001046	core promoter sequence-specific DNA binding	5/2115	44/18639	0.113636363636364	1.00145067698259	0.569000821542651	0.873025770308087
GO:0043014	alpha-tubulin binding	5/2115	44/18639	0.113636363636364	1.00145067698259	0.569000821542651	0.873025770308087
GO:0001217	DNA-binding transcription repressor activity	31/2115	278/18639	0.111510791366906	0.982718506046227	0.569847619730877	0.87325485912247
GO:0004623	phospholipase A2 activity	4/2115	35/18639	0.114285714285714	1.00717325227964	0.572683787846034	0.875183230171916
GO:0043015	gamma-tubulin binding	4/2115	35/18639	0.114285714285714	1.00717325227964	0.572683787846034	0.875183230171916
GO:0005516	calmodulin binding	23/2115	207/18639	0.111111111111111	0.97919621749409	0.575745125533394	0.875183230171916
GO:0005160	transforming growth factor beta receptor binding	3/2115	26/18639	0.115384615384615	1.01685761047463	0.578795299187178	0.875183230171916
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	3/2115	26/18639	0.115384615384615	1.01685761047463	0.578795299187178	0.875183230171916
GO:0008157	protein phosphatase 1 binding	3/2115	26/18639	0.115384615384615	1.01685761047463	0.578795299187178	0.875183230171916
GO:0008198	ferrous iron binding	3/2115	26/18639	0.115384615384615	1.01685761047463	0.578795299187178	0.875183230171916
GO:0015216	purine nucleotide transmembrane transporter activity	3/2115	26/18639	0.115384615384615	1.01685761047463	0.578795299187178	0.875183230171916
GO:0034237	protein kinase A regulatory subunit binding	3/2115	26/18639	0.115384615384615	1.01685761047463	0.578795299187178	0.875183230171916
GO:0050750	low-density lipoprotein particle receptor binding	3/2115	26/18639	0.115384615384615	1.01685761047463	0.578795299187178	0.875183230171916
GO:0120014	phospholipid transfer activity	3/2115	26/18639	0.115384615384615	1.01685761047463	0.578795299187178	0.875183230171916
GO:0005518	collagen binding	8/2115	72/18639	0.111111111111111	0.97919621749409	0.580499924379321	0.876701936457068
GO:0004519	endonuclease activity	14/2115	127/18639	0.110236220472441	0.971486011057128	0.58768066509313	0.880791344471562
GO:0004549	tRNA-specific ribonuclease activity	2/2115	17/18639	0.117647058823529	1.03679599499374	0.590242761990128	0.880791344471562
GO:0015278	intracellularly gated calcium channel activity	2/2115	17/18639	0.117647058823529	1.03679599499374	0.590242761990128	0.880791344471562
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/2115	17/18639	0.117647058823529	1.03679599499374	0.590242761990128	0.880791344471562
GO:0017110	nucleoside diphosphate phosphatase activity	2/2115	17/18639	0.117647058823529	1.03679599499374	0.590242761990128	0.880791344471562
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/2115	17/18639	0.117647058823529	1.03679599499374	0.590242761990128	0.880791344471562
GO:0030548	acetylcholine receptor regulator activity	2/2115	17/18639	0.117647058823529	1.03679599499374	0.590242761990128	0.880791344471562
GO:0032977	membrane insertase activity	2/2115	17/18639	0.117647058823529	1.03679599499374	0.590242761990128	0.880791344471562
GO:0038191	neuropilin binding	2/2115	17/18639	0.117647058823529	1.03679599499374	0.590242761990128	0.880791344471562
GO:0045236	CXCR chemokine receptor binding	2/2115	17/18639	0.117647058823529	1.03679599499374	0.590242761990128	0.880791344471562
GO:0004521	RNA endonuclease activity	8/2115	73/18639	0.10958904109589	0.965782570679102	0.596649905423595	0.889292478083739
GO:0001671	ATPase activator activity	3/2115	27/18639	0.111111111111111	0.97919621749409	0.605187590385739	0.899875134397797
GO:0016405	CoA-ligase activity	3/2115	27/18639	0.111111111111111	0.97919621749409	0.605187590385739	0.899875134397797
GO:0004180	carboxypeptidase activity	5/2115	46/18639	0.108695652173913	0.95790934320074	0.609788484751846	0.90564078636929
GO:0032182	ubiquitin-like protein binding	13/2115	120/18639	0.108333333333333	0.954716312056738	0.613547594895794	0.910144062570537
GO:0022829	wide pore channel activity	4/2115	37/18639	0.108108108108108	0.952731454859114	0.617959433374613	0.914198437544976
GO:0030551	cyclic nucleotide binding	4/2115	37/18639	0.108108108108108	0.952731454859114	0.617959433374613	0.914198437544976
GO:0008525	phosphatidylcholine transporter activity	2/2115	18/18639	0.111111111111111	0.97919621749409	0.622122259415591	0.914198437544976
GO:0016854	racemase and epimerase activity	2/2115	18/18639	0.111111111111111	0.97919621749409	0.622122259415591	0.914198437544976
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/2115	18/18639	0.111111111111111	0.97919621749409	0.622122259415591	0.914198437544976
GO:0035615	clathrin adaptor activity	2/2115	18/18639	0.111111111111111	0.97919621749409	0.622122259415591	0.914198437544976
GO:0050811	GABA receptor binding	2/2115	18/18639	0.111111111111111	0.97919621749409	0.622122259415591	0.914198437544976
GO:0070064	proline-rich region binding	2/2115	18/18639	0.111111111111111	0.97919621749409	0.622122259415591	0.914198437544976
GO:0016798	hydrolase activity, acting on glycosyl bonds	14/2115	130/18639	0.107692307692308	0.949067103109656	0.623758401879086	0.915528158443864
GO:0016874	ligase activity	18/2115	167/18639	0.107784431137725	0.949878965473309	0.628382314487541	0.921234962222953
GO:0045499	chemorepellent activity	3/2115	28/18639	0.107142857142857	0.944224924012158	0.630456805363084	0.922116729339465
GO:0051959	dynein light intermediate chain binding	3/2115	28/18639	0.107142857142857	0.944224924012158	0.630456805363084	0.922116729339465
GO:0008235	metalloexopeptidase activity	7/2115	66/18639	0.106060606060606	0.934687298517086	0.633102869755674	0.92490640949137
GO:0005501	retinoid binding	4/2115	38/18639	0.105263157894737	0.927659574468085	0.639433958868956	0.928716111410142
GO:0019840	isoprenoid binding	4/2115	38/18639	0.105263157894737	0.927659574468085	0.639433958868956	0.928716111410142
GO:0005525	GTP binding	41/2115	378/18639	0.108465608465608	0.955882021839469	0.646006492020754	0.928716111410142
GO:0016741	transferase activity, transferring one-carbon groups	23/2115	215/18639	0.106976744186047	0.942761009401286	0.650630670042806	0.928716111410142
GO:0099106	ion channel regulator activity	17/2115	160/18639	0.10625	0.936356382978723	0.650797425927929	0.928716111410142
GO:0030506	ankyrin binding	2/2115	19/18639	0.105263157894737	0.927659574468085	0.652046732363564	0.928716111410142
GO:0034987	immunoglobulin receptor binding	2/2115	19/18639	0.105263157894737	0.927659574468085	0.652046732363564	0.928716111410142
GO:0042834	peptidoglycan binding	2/2115	19/18639	0.105263157894737	0.927659574468085	0.652046732363564	0.928716111410142
GO:0043395	heparan sulfate proteoglycan binding	2/2115	19/18639	0.105263157894737	0.927659574468085	0.652046732363564	0.928716111410142
GO:0046624	sphingolipid transporter activity	2/2115	19/18639	0.105263157894737	0.927659574468085	0.652046732363564	0.928716111410142
GO:0140036	ubiquitin-modified protein reader activity	2/2115	19/18639	0.105263157894737	0.927659574468085	0.652046732363564	0.928716111410142
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	9/2115	86/18639	0.104651162790698	0.922266204849085	0.652425762414182	0.928716111410142
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	3/2115	29/18639	0.103448275862069	0.911665443873808	0.654581640100014	0.928716111410142
GO:0035250	UDP-galactosyltransferase activity	3/2115	29/18639	0.103448275862069	0.911665443873808	0.654581640100014	0.928716111410142
GO:0097472	cyclin-dependent protein kinase activity	3/2115	29/18639	0.103448275862069	0.911665443873808	0.654581640100014	0.928716111410142
GO:0003724	RNA helicase activity	8/2115	77/18639	0.103896103896104	0.915612047526941	0.657953845150241	0.928716111410142
GO:0035401	histone H3Y41 kinase activity	12/2115	115/18639	0.104347826086957	0.91959296947271	0.665008445820925	0.928716111410142
GO:0140801	histone H2AXY142 kinase activity	12/2115	115/18639	0.104347826086957	0.91959296947271	0.665008445820925	0.928716111410142
GO:0005004	GPI-linked ephrin receptor activity	5/2115	49/18639	0.102040816326531	0.899261832392531	0.666545387658033	0.928716111410142
GO:0005008	hepatocyte growth factor receptor activity	5/2115	49/18639	0.102040816326531	0.899261832392531	0.666545387658033	0.928716111410142
GO:0005009	insulin receptor activity	5/2115	49/18639	0.102040816326531	0.899261832392531	0.666545387658033	0.928716111410142
GO:0005011	macrophage colony-stimulating factor receptor activity	5/2115	49/18639	0.102040816326531	0.899261832392531	0.666545387658033	0.928716111410142
GO:0005018	platelet-derived growth factor alpha-receptor activity	5/2115	49/18639	0.102040816326531	0.899261832392531	0.666545387658033	0.928716111410142
GO:0005020	stem cell factor receptor activity	5/2115	49/18639	0.102040816326531	0.899261832392531	0.666545387658033	0.928716111410142
GO:0008288	boss receptor activity	5/2115	49/18639	0.102040816326531	0.899261832392531	0.666545387658033	0.928716111410142
GO:0036332	placental growth factor receptor activity	5/2115	49/18639	0.102040816326531	0.899261832392531	0.666545387658033	0.928716111410142
GO:0038062	protein tyrosine kinase collagen receptor activity	5/2115	49/18639	0.102040816326531	0.899261832392531	0.666545387658033	0.928716111410142
GO:0060175	brain-derived neurotrophic factor receptor activity	5/2115	49/18639	0.102040816326531	0.899261832392531	0.666545387658033	0.928716111410142
GO:0031593	polyubiquitin modification-dependent protein binding	6/2115	59/18639	0.101694915254237	0.896213487197981	0.673233738860046	0.928716111410142
GO:0036002	pre-mRNA binding	6/2115	59/18639	0.101694915254237	0.896213487197981	0.673233738860046	0.928716111410142
GO:0070063	RNA polymerase binding	6/2115	59/18639	0.101694915254237	0.896213487197981	0.673233738860046	0.928716111410142
GO:0008106	alcohol dehydrogenase (NADP+) activity	3/2115	30/18639	0.1	0.881276595744681	0.677552830780466	0.928716111410142
GO:0035925	mRNA 3'-UTR AU-rich region binding	3/2115	30/18639	0.1	0.881276595744681	0.677552830780466	0.928716111410142
GO:0070566	adenylyltransferase activity	3/2115	30/18639	0.1	0.881276595744681	0.677552830780466	0.928716111410142
GO:0071855	neuropeptide receptor binding	4/2115	40/18639	0.1	0.881276595744681	0.679953445772895	0.928716111410142
GO:0015464	acetylcholine receptor activity	2/2115	20/18639	0.1	0.881276595744681	0.680049185592147	0.928716111410142
GO:0016408	C-acyltransferase activity	2/2115	20/18639	0.1	0.881276595744681	0.680049185592147	0.928716111410142
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	2/2115	20/18639	0.1	0.881276595744681	0.680049185592147	0.928716111410142
GO:0031418	L-ascorbic acid binding	2/2115	20/18639	0.1	0.881276595744681	0.680049185592147	0.928716111410142
GO:0061608	nuclear import signal receptor activity	2/2115	20/18639	0.1	0.881276595744681	0.680049185592147	0.928716111410142
GO:0005006	epidermal growth factor receptor activity	5/2115	50/18639	0.1	0.881276595744681	0.684212139194987	0.928716111410142
GO:0035091	phosphatidylinositol binding	30/2115	284/18639	0.105633802816901	0.930925981420437	0.690150003489099	0.928716111410142
GO:0015081	sodium ion transmembrane transporter activity	17/2115	164/18639	0.103658536585366	0.913518422418267	0.690832125003833	0.928716111410142
GO:0016877	ligase activity, forming carbon-sulfur bonds	4/2115	41/18639	0.0975609756097561	0.859782044628957	0.698977524002527	0.928716111410142
GO:0017080	sodium channel regulator activity	4/2115	41/18639	0.0975609756097561	0.859782044628957	0.698977524002527	0.928716111410142
GO:0005184	neuropeptide hormone activity	3/2115	31/18639	0.0967741935483871	0.852848318462594	0.699371520622674	0.928716111410142
GO:0005452	solute:inorganic anion antiporter activity	3/2115	31/18639	0.0967741935483871	0.852848318462594	0.699371520622674	0.928716111410142
GO:0016878	acid-thiol ligase activity	3/2115	31/18639	0.0967741935483871	0.852848318462594	0.699371520622674	0.928716111410142
GO:0004090	carbonyl reductase (NADPH) activity	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0005381	iron ion transmembrane transporter activity	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0008140	cAMP response element binding protein binding	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0008190	eukaryotic initiation factor 4E binding	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0008239	dipeptidyl-peptidase activity	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0008519	ammonium channel activity	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0015187	glycine transmembrane transporter activity	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0015643	toxic substance binding	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0016783	sulfurtransferase activity	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0019911	structural constituent of myelin sheath	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0032052	bile acid binding	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0035256	G protein-coupled glutamate receptor binding	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0042975	peroxisome proliferator activated receptor binding	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0043295	glutathione binding	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0050308	sugar-phosphatase activity	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0051378	serotonin binding	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0070097	delta-catenin binding	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0070513	death domain binding	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0097177	mitochondrial ribosome binding	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0099122	RNA polymerase II C-terminal domain binding	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0140940	histone H2A methyltransferase activity	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0140999	histone H3K4 trimethyltransferase activity	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0141109	transporter activator activity	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:1905394	retromer complex binding	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:1990259	histone H2AQ104 methyltransferase activity	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:1990757	ubiquitin ligase activator activity	1/2115	10/18639	0.1	0.881276595744681	0.700227682115696	0.928716111410142
GO:0015103	inorganic anion transmembrane transporter activity	17/2115	165/18639	0.103030303030303	0.907981947130883	0.700417630806814	0.928716111410142
GO:0016757	glycosyltransferase activity	28/2115	267/18639	0.104868913857678	0.924185194039366	0.700598026705352	0.928716111410142
GO:0005010	insulin-like growth factor receptor activity	5/2115	51/18639	0.0980392156862745	0.863996662494785	0.701235437135184	0.928716111410142
GO:0005021	vascular endothelial growth factor receptor activity	5/2115	51/18639	0.0980392156862745	0.863996662494785	0.701235437135184	0.928716111410142
GO:0005030	neurotrophin receptor activity	5/2115	51/18639	0.0980392156862745	0.863996662494785	0.701235437135184	0.928716111410142
GO:0005048	signal sequence binding	5/2115	51/18639	0.0980392156862745	0.863996662494785	0.701235437135184	0.928716111410142
GO:0016830	carbon-carbon lyase activity	5/2115	51/18639	0.0980392156862745	0.863996662494785	0.701235437135184	0.928716111410142
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	2/2115	21/18639	0.0952380952380952	0.839311043566363	0.706180301966817	0.928716111410142
GO:0009931	calcium-dependent protein serine/threonine kinase activity	2/2115	21/18639	0.0952380952380952	0.839311043566363	0.706180301966817	0.928716111410142
GO:0009975	cyclase activity	2/2115	21/18639	0.0952380952380952	0.839311043566363	0.706180301966817	0.928716111410142
GO:0010314	phosphatidylinositol-5-phosphate binding	2/2115	21/18639	0.0952380952380952	0.839311043566363	0.706180301966817	0.928716111410142
GO:0036122	BMP binding	2/2115	21/18639	0.0952380952380952	0.839311043566363	0.706180301966817	0.928716111410142
GO:0051010	microtubule plus-end binding	2/2115	21/18639	0.0952380952380952	0.839311043566363	0.706180301966817	0.928716111410142
GO:0051428	peptide hormone receptor binding	2/2115	21/18639	0.0952380952380952	0.839311043566363	0.706180301966817	0.928716111410142
GO:0140312	cargo adaptor activity	2/2115	21/18639	0.0952380952380952	0.839311043566363	0.706180301966817	0.928716111410142
GO:0005543	phospholipid binding	53/2115	497/18639	0.106639839034205	0.939791943148251	0.707545869242583	0.929535601565282
GO:0019894	kinesin binding	4/2115	42/18639	0.0952380952380952	0.839311043566363	0.717173664346777	0.932348441439489
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	9/2115	91/18639	0.0989010989010989	0.871592237549684	0.718043021604411	0.932348441439489
GO:0008378	galactosyltransferase activity	3/2115	32/18639	0.09375	0.826196808510638	0.720047748749896	0.932348441439489
GO:0120015	sterol transfer activity	3/2115	32/18639	0.09375	0.826196808510638	0.720047748749896	0.932348441439489
GO:0160041	neuropeptide activity	3/2115	32/18639	0.09375	0.826196808510638	0.720047748749896	0.932348441439489
GO:0005201	extracellular matrix structural constituent	17/2115	168/18639	0.101190476190476	0.89176798378926	0.72810637806374	0.932348441439489
GO:0008234	cysteine-type peptidase activity	19/2115	187/18639	0.101604278074866	0.895414722949141	0.729759137707332	0.932348441439489
GO:0016881	acid-amino acid ligase activity	2/2115	22/18639	0.0909090909090909	0.801160541586074	0.73050400910787	0.932348441439489
GO:0140035	ubiquitin-like protein reader activity	2/2115	22/18639	0.0909090909090909	0.801160541586074	0.73050400910787	0.932348441439489
GO:0015108	chloride transmembrane transporter activity	12/2115	121/18639	0.0991735537190083	0.873993318093898	0.732070517537527	0.932348441439489
GO:0016251	RNA polymerase II general transcription initiation factor activity	5/2115	53/18639	0.0943396226415094	0.831393014853473	0.733336703112115	0.932348441439489
GO:0038064	collagen receptor activity	5/2115	53/18639	0.0943396226415094	0.831393014853473	0.733336703112115	0.932348441439489
GO:0051018	protein kinase A binding	5/2115	53/18639	0.0943396226415094	0.831393014853473	0.733336703112115	0.932348441439489
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0003953	NAD+ nucleosidase activity	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0004016	adenylate cyclase activity	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0005114	type II transforming growth factor beta receptor binding	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0008172	S-methyltransferase activity	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0008432	JUN kinase binding	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0016594	glycine binding	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0019203	carbohydrate phosphatase activity	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0032404	mismatch repair complex binding	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0048185	activin binding	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0048407	platelet-derived growth factor binding	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0140537	transcription regulator activator activity	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0180030	inositol phosphate kinase activity	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:1900750	oligopeptide binding	1/2115	11/18639	0.0909090909090909	0.801160541586074	0.734261631996275	0.932348441439489
GO:0001540	amyloid-beta binding	8/2115	83/18639	0.0963855421686747	0.84942322481415	0.738784996059169	0.933727231291024
GO:0019239	deaminase activity	3/2115	33/18639	0.0909090909090909	0.801160541586074	0.739599065019172	0.933727231291024
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	12/2115	122/18639	0.0983606557377049	0.866829438437391	0.74234609719493	0.933727231291024
GO:0005253	monoatomic anion channel activity	10/2115	103/18639	0.0970873786407767	0.855608345383185	0.745232586635275	0.933727231291024
GO:0004527	exonuclease activity	8/2115	84/18639	0.0952380952380952	0.839311043566363	0.750878637423335	0.933727231291024
GO:0030020	extracellular matrix structural constituent conferring tensile strength	4/2115	44/18639	0.0909090909090909	0.801160541586074	0.751099556606209	0.933727231291024
GO:0016849	phosphorus-oxygen lyase activity	2/2115	23/18639	0.0869565217391304	0.766327474560592	0.753093823789359	0.933727231291024
GO:0042171	lysophosphatidic acid acyltransferase activity	2/2115	23/18639	0.0869565217391304	0.766327474560592	0.753093823789359	0.933727231291024
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	2/2115	23/18639	0.0869565217391304	0.766327474560592	0.753093823789359	0.933727231291024
GO:0071617	lysophospholipid acyltransferase activity	2/2115	23/18639	0.0869565217391304	0.766327474560592	0.753093823789359	0.933727231291024
GO:0016831	carboxy-lyase activity	3/2115	34/18639	0.0882352941176471	0.777596996245307	0.758049271071329	0.933727231291024
GO:0030332	cyclin binding	3/2115	34/18639	0.0882352941176471	0.777596996245307	0.758049271071329	0.933727231291024
GO:0051427	hormone receptor binding	3/2115	34/18639	0.0882352941176471	0.777596996245307	0.758049271071329	0.933727231291024
GO:0008083	growth factor activity	16/2115	162/18639	0.0987654320987654	0.870396637772524	0.758539111660258	0.933727231291024
GO:0120013	lipid transfer activity	6/2115	65/18639	0.0923076923076923	0.813486088379705	0.761405106767672	0.933727231291024
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0003995	acyl-CoA dehydrogenase activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0004000	adenosine deaminase activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0004032	aldose reductase (NADPH) activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0004300	enoyl-CoA hydratase activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0005078	MAP-kinase scaffold activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0005165	neurotrophin receptor binding	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0005247	voltage-gated chloride channel activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0008603	cAMP-dependent protein kinase regulator activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0015368	calcium:monoatomic cation antiporter activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0034452	dynactin binding	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0035251	UDP-glucosyltransferase activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0035497	cAMP response element binding	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0036009	protein-glutamine N-methyltransferase activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0070679	inositol 1,4,5 trisphosphate binding	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0140900	chloride:bicarbonate antiporter activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:1990817	poly(A) RNA polymerase activity	1/2115	12/18639	0.0833333333333333	0.734397163120567	0.764433236480271	0.933727231291024
GO:0004715	non-membrane spanning protein tyrosine kinase activity	4/2115	45/18639	0.0888888888888889	0.783356973995272	0.766848429821735	0.933943807526082
GO:0042605	peptide antigen binding	4/2115	45/18639	0.0888888888888889	0.783356973995272	0.766848429821735	0.933943807526082
GO:0051539	4 iron, 4 sulfur cluster binding	4/2115	45/18639	0.0888888888888889	0.783356973995272	0.766848429821735	0.933943807526082
GO:0101005	deubiquitinase activity	11/2115	115/18639	0.0956521739130435	0.842960222016651	0.768917145047431	0.934290402706212
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	2/2115	24/18639	0.0833333333333333	0.734397163120567	0.774029854791131	0.934290402706212
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	2/2115	24/18639	0.0833333333333333	0.734397163120567	0.774029854791131	0.934290402706212
GO:0004806	triacylglycerol lipase activity	2/2115	24/18639	0.0833333333333333	0.734397163120567	0.774029854791131	0.934290402706212
GO:0005315	phosphate transmembrane transporter activity	2/2115	24/18639	0.0833333333333333	0.734397163120567	0.774029854791131	0.934290402706212
GO:0015149	hexose transmembrane transporter activity	2/2115	24/18639	0.0833333333333333	0.734397163120567	0.774029854791131	0.934290402706212
GO:0055056	D-glucose transmembrane transporter activity	2/2115	24/18639	0.0833333333333333	0.734397163120567	0.774029854791131	0.934290402706212
GO:0000175	3'-5'-RNA exonuclease activity	3/2115	35/18639	0.0857142857142857	0.755379939209726	0.775427285123701	0.934290402706212
GO:0034061	DNA polymerase activity	3/2115	35/18639	0.0857142857142857	0.755379939209726	0.775427285123701	0.934290402706212
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	4/2115	46/18639	0.0869565217391304	0.766327474560592	0.781806519828391	0.934290402706212
GO:0016500	protein-hormone receptor activity	6/2115	67/18639	0.0895522388059701	0.789202921562401	0.786540897424511	0.934290402706212
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	6/2115	67/18639	0.0895522388059701	0.789202921562401	0.786540897424511	0.934290402706212
GO:0019783	ubiquitin-like protein peptidase activity	12/2115	127/18639	0.094488188976378	0.832702295191824	0.789744820220052	0.934290402706212
GO:0004465	lipoprotein lipase activity	1/2115	13/18639	0.0769230769230769	0.677905073649755	0.791180630308812	0.934290402706212
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/2115	13/18639	0.0769230769230769	0.677905073649755	0.791180630308812	0.934290402706212
GO:0008035	high-density lipoprotein particle binding	1/2115	13/18639	0.0769230769230769	0.677905073649755	0.791180630308812	0.934290402706212
GO:0008253	5'-nucleotidase activity	1/2115	13/18639	0.0769230769230769	0.677905073649755	0.791180630308812	0.934290402706212
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/2115	13/18639	0.0769230769230769	0.677905073649755	0.791180630308812	0.934290402706212
GO:0035673	oligopeptide transmembrane transporter activity	1/2115	13/18639	0.0769230769230769	0.677905073649755	0.791180630308812	0.934290402706212
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/2115	13/18639	0.0769230769230769	0.677905073649755	0.791180630308812	0.934290402706212
GO:0046975	histone H3K36 methyltransferase activity	1/2115	13/18639	0.0769230769230769	0.677905073649755	0.791180630308812	0.934290402706212
GO:0089720	caspase binding	1/2115	13/18639	0.0769230769230769	0.677905073649755	0.791180630308812	0.934290402706212
GO:0097157	pre-mRNA intronic binding	1/2115	13/18639	0.0769230769230769	0.677905073649755	0.791180630308812	0.934290402706212
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/2115	13/18639	0.0769230769230769	0.677905073649755	0.791180630308812	0.934290402706212
GO:0140852	histone ubiquitin ligase activity	1/2115	13/18639	0.0769230769230769	0.677905073649755	0.791180630308812	0.934290402706212
GO:0000993	RNA polymerase II complex binding	3/2115	36/18639	0.0833333333333333	0.734397163120567	0.791766126023523	0.934290402706212
GO:0004033	aldo-keto reductase (NADPH) activity	3/2115	36/18639	0.0833333333333333	0.734397163120567	0.791766126023523	0.934290402706212
GO:0004190	aspartic-type endopeptidase activity	3/2115	36/18639	0.0833333333333333	0.734397163120567	0.791766126023523	0.934290402706212
GO:0005484	SNAP receptor activity	3/2115	36/18639	0.0833333333333333	0.734397163120567	0.791766126023523	0.934290402706212
GO:0008139	nuclear localization sequence binding	2/2115	25/18639	0.08	0.705021276595745	0.793396361946861	0.934290402706212
GO:0015271	outward rectifier potassium channel activity	2/2115	25/18639	0.08	0.705021276595745	0.793396361946861	0.934290402706212
GO:0017025	TBP-class protein binding	2/2115	25/18639	0.08	0.705021276595745	0.793396361946861	0.934290402706212
GO:0047617	fatty acyl-CoA hydrolase activity	2/2115	25/18639	0.08	0.705021276595745	0.793396361946861	0.934290402706212
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/2115	25/18639	0.08	0.705021276595745	0.793396361946861	0.934290402706212
GO:0004197	cysteine-type endopeptidase activity	8/2115	88/18639	0.0909090909090909	0.801160541586074	0.79528133972748	0.934290402706212
GO:0061733	protein-lysine-acetyltransferase activity	4/2115	47/18639	0.0851063829787234	0.750022634676324	0.795991409386135	0.934290402706212
GO:0140359	ABC-type transporter activity	4/2115	47/18639	0.0851063829787234	0.750022634676324	0.795991409386135	0.934290402706212
GO:0140938	histone H3 methyltransferase activity	4/2115	47/18639	0.0851063829787234	0.750022634676324	0.795991409386135	0.934290402706212
GO:0140223	general transcription initiation factor activity	6/2115	68/18639	0.0882352941176471	0.777596996245307	0.798328759458389	0.934290402706212
GO:0008408	3'-5' exonuclease activity	5/2115	58/18639	0.0862068965517241	0.759721203228173	0.802387401173607	0.934290402706212
GO:0016758	hexosyltransferase activity	19/2115	197/18639	0.0964467005076142	0.84996219894157	0.806163245182648	0.934290402706212
GO:0030280	structural constituent of skin epidermis	3/2115	37/18639	0.0810810810810811	0.714548591144336	0.807102010669015	0.934290402706212
GO:0070001	aspartic-type peptidase activity	3/2115	37/18639	0.0810810810810811	0.714548591144336	0.807102010669015	0.934290402706212
GO:0140767	enzyme-substrate adaptor activity	13/2115	139/18639	0.0935251798561151	0.824215521200061	0.808198730683108	0.934290402706212
GO:0032266	phosphatidylinositol-3-phosphate binding	4/2115	48/18639	0.0833333333333333	0.734397163120567	0.809423035336758	0.934290402706212
GO:0038187	pattern recognition receptor activity	4/2115	48/18639	0.0833333333333333	0.734397163120567	0.809423035336758	0.934290402706212
GO:0004112	cyclic-nucleotide phosphodiesterase activity	2/2115	26/18639	0.0769230769230769	0.677905073649755	0.811279783843501	0.934290402706212
GO:0005227	calcium-activated cation channel activity	2/2115	26/18639	0.0769230769230769	0.677905073649755	0.811279783843501	0.934290402706212
GO:0015145	monosaccharide transmembrane transporter activity	2/2115	26/18639	0.0769230769230769	0.677905073649755	0.811279783843501	0.934290402706212
GO:0016289	acyl-CoA hydrolase activity	2/2115	26/18639	0.0769230769230769	0.677905073649755	0.811279783843501	0.934290402706212
GO:0030247	polysaccharide binding	2/2115	26/18639	0.0769230769230769	0.677905073649755	0.811279783843501	0.934290402706212
GO:0051139	metal cation:proton antiporter activity	2/2115	26/18639	0.0769230769230769	0.677905073649755	0.811279783843501	0.934290402706212
GO:0052742	phosphatidylinositol kinase activity	2/2115	26/18639	0.0769230769230769	0.677905073649755	0.811279783843501	0.934290402706212
GO:0004222	metalloendopeptidase activity	10/2115	110/18639	0.0909090909090909	0.801160541586074	0.813972382820529	0.934290402706212
GO:0004065	arylsulfatase activity	1/2115	14/18639	0.0714285714285714	0.629483282674772	0.814892268175067	0.934290402706212
GO:0005161	platelet-derived growth factor receptor binding	1/2115	14/18639	0.0714285714285714	0.629483282674772	0.814892268175067	0.934290402706212
GO:0005545	1-phosphatidylinositol binding	1/2115	14/18639	0.0714285714285714	0.629483282674772	0.814892268175067	0.934290402706212
GO:0008392	arachidonate epoxygenase activity	1/2115	14/18639	0.0714285714285714	0.629483282674772	0.814892268175067	0.934290402706212
GO:0030983	mismatched DNA binding	1/2115	14/18639	0.0714285714285714	0.629483282674772	0.814892268175067	0.934290402706212
GO:0032454	histone H3K9 demethylase activity	1/2115	14/18639	0.0714285714285714	0.629483282674772	0.814892268175067	0.934290402706212
GO:0034236	protein kinase A catalytic subunit binding	1/2115	14/18639	0.0714285714285714	0.629483282674772	0.814892268175067	0.934290402706212
GO:0042043	neurexin family protein binding	1/2115	14/18639	0.0714285714285714	0.629483282674772	0.814892268175067	0.934290402706212
GO:0042813	Wnt receptor activity	1/2115	14/18639	0.0714285714285714	0.629483282674772	0.814892268175067	0.934290402706212
GO:1901612	cardiolipin binding	1/2115	14/18639	0.0714285714285714	0.629483282674772	0.814892268175067	0.934290402706212
GO:0000146	microfilament motor activity	3/2115	38/18639	0.0789473684210526	0.695744680851064	0.821473557966163	0.939463662099603
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	3/2115	38/18639	0.0789473684210526	0.695744680851064	0.821473557966163	0.939463662099603
GO:0004540	RNA nuclease activity	11/2115	121/18639	0.0909090909090909	0.801160541586074	0.822509293248454	0.939463662099603
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	22/2115	229/18639	0.0960698689956332	0.846641271021091	0.825846657289338	0.939463662099603
GO:0004683	calcium/calmodulin-dependent protein kinase activity	2/2115	27/18639	0.0740740740740741	0.652797478329393	0.827767159320122	0.939463662099603
GO:0005044	scavenger receptor activity	2/2115	27/18639	0.0740740740740741	0.652797478329393	0.827767159320122	0.939463662099603
GO:0008395	steroid hydroxylase activity	2/2115	27/18639	0.0740740740740741	0.652797478329393	0.827767159320122	0.939463662099603
GO:0042277	peptide binding	24/2115	249/18639	0.0963855421686747	0.84942322481415	0.83019623362168	0.939463662099603
GO:0004089	carbonate dehydratase activity	1/2115	15/18639	0.0666666666666667	0.587517730496454	0.835912555574247	0.939463662099603
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/2115	15/18639	0.0666666666666667	0.587517730496454	0.835912555574247	0.939463662099603
GO:0008020	G protein-coupled photoreceptor activity	1/2115	15/18639	0.0666666666666667	0.587517730496454	0.835912555574247	0.939463662099603
GO:0008252	nucleotidase activity	1/2115	15/18639	0.0666666666666667	0.587517730496454	0.835912555574247	0.939463662099603
GO:0010181	FMN binding	1/2115	15/18639	0.0666666666666667	0.587517730496454	0.835912555574247	0.939463662099603
GO:0015929	hexosaminidase activity	1/2115	15/18639	0.0666666666666667	0.587517730496454	0.835912555574247	0.939463662099603
GO:0030553	cGMP binding	1/2115	15/18639	0.0666666666666667	0.587517730496454	0.835912555574247	0.939463662099603
GO:0031005	filamin binding	1/2115	15/18639	0.0666666666666667	0.587517730496454	0.835912555574247	0.939463662099603
GO:0045504	dynein heavy chain binding	1/2115	15/18639	0.0666666666666667	0.587517730496454	0.835912555574247	0.939463662099603
GO:0050700	CARD domain binding	1/2115	15/18639	0.0666666666666667	0.587517730496454	0.835912555574247	0.939463662099603
GO:0050780	dopamine receptor binding	1/2115	15/18639	0.0666666666666667	0.587517730496454	0.835912555574247	0.939463662099603
GO:0051371	muscle alpha-actinin binding	1/2115	15/18639	0.0666666666666667	0.587517730496454	0.835912555574247	0.939463662099603
GO:0141050	histone H3K deacetylase activity	1/2115	15/18639	0.0666666666666667	0.587517730496454	0.835912555574247	0.939463662099603
GO:0141051	histone H4K deacetylase activity	1/2115	15/18639	0.0666666666666667	0.587517730496454	0.835912555574247	0.939463662099603
GO:0046966	nuclear thyroid hormone receptor binding	2/2115	28/18639	0.0714285714285714	0.629483282674772	0.842944878855279	0.944822729030268
GO:0051019	mitogen-activated protein kinase binding	2/2115	28/18639	0.0714285714285714	0.629483282674772	0.842944878855279	0.944822729030268
GO:0051119	sugar transmembrane transporter activity	2/2115	28/18639	0.0714285714285714	0.629483282674772	0.842944878855279	0.944822729030268
GO:0030544	Hsp70 protein binding	4/2115	51/18639	0.0784313725490196	0.691197329995828	0.845424488168636	0.94528243525875
GO:0004175	endopeptidase activity	40/2115	405/18639	0.0987654320987654	0.870396637772524	0.847121767643358	0.94528243525875
GO:0004532	RNA exonuclease activity	3/2115	40/18639	0.075	0.660957446808511	0.847486036205152	0.94528243525875
GO:0015144	carbohydrate transmembrane transporter activity	3/2115	40/18639	0.075	0.660957446808511	0.847486036205152	0.94528243525875
GO:0008194	UDP-glycosyltransferase activity	13/2115	145/18639	0.0896551724137931	0.7901100513573	0.85172838352361	0.94528243525875
GO:0000062	fatty-acyl-CoA binding	1/2115	16/18639	0.0625	0.550797872340426	0.854546841708293	0.94528243525875
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/2115	16/18639	0.0625	0.550797872340426	0.854546841708293	0.94528243525875
GO:0008391	arachidonate monooxygenase activity	1/2115	16/18639	0.0625	0.550797872340426	0.854546841708293	0.94528243525875
GO:0015385	sodium:proton antiporter activity	1/2115	16/18639	0.0625	0.550797872340426	0.854546841708293	0.94528243525875
GO:0015562	efflux transmembrane transporter activity	1/2115	16/18639	0.0625	0.550797872340426	0.854546841708293	0.94528243525875
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/2115	16/18639	0.0625	0.550797872340426	0.854546841708293	0.94528243525875
GO:0019841	retinol binding	1/2115	16/18639	0.0625	0.550797872340426	0.854546841708293	0.94528243525875
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/2115	16/18639	0.0625	0.550797872340426	0.854546841708293	0.94528243525875
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/2115	16/18639	0.0625	0.550797872340426	0.854546841708293	0.94528243525875
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	4/2115	52/18639	0.0769230769230769	0.677905073649755	0.856075638524951	0.94528243525875
GO:0016417	S-acyltransferase activity	2/2115	29/18639	0.0689655172413793	0.607776962582538	0.856897711355669	0.94528243525875
GO:0099604	ligand-gated calcium channel activity	2/2115	29/18639	0.0689655172413793	0.607776962582538	0.856897711355669	0.94528243525875
GO:0008276	protein methyltransferase activity	8/2115	95/18639	0.0842105263157895	0.742127659574468	0.85828493647814	0.94528243525875
GO:0035064	methylated histone binding	6/2115	74/18639	0.0810810810810811	0.714548591144336	0.858726869245734	0.94528243525875
GO:0001727	lipid kinase activity	3/2115	41/18639	0.0731707317073171	0.644836533471718	0.859210392431675	0.94528243525875
GO:0008227	G protein-coupled amine receptor activity	3/2115	41/18639	0.0731707317073171	0.644836533471718	0.859210392431675	0.94528243525875
GO:0008146	sulfotransferase activity	4/2115	53/18639	0.0754716981132075	0.665114411882778	0.866095143456611	0.946679201438133
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/2115	30/18639	0.0666666666666667	0.587517730496454	0.869708059968184	0.946679201438133
GO:0022839	monoatomic ion-gated channel activity	2/2115	30/18639	0.0666666666666667	0.587517730496454	0.869708059968184	0.946679201438133
GO:0048019	receptor antagonist activity	2/2115	30/18639	0.0666666666666667	0.587517730496454	0.869708059968184	0.946679201438133
GO:0004402	histone acetyltransferase activity	3/2115	42/18639	0.0714285714285714	0.629483282674772	0.870136294592052	0.946679201438133
GO:0043175	RNA polymerase core enzyme binding	3/2115	42/18639	0.0714285714285714	0.629483282674772	0.870136294592052	0.946679201438133
GO:0008429	phosphatidylethanolamine binding	1/2115	17/18639	0.0588235294117647	0.518397997496871	0.871065846690678	0.946679201438133
GO:0008484	sulfuric ester hydrolase activity	1/2115	17/18639	0.0588235294117647	0.518397997496871	0.871065846690678	0.946679201438133
GO:0008569	minus-end-directed microtubule motor activity	1/2115	17/18639	0.0588235294117647	0.518397997496871	0.871065846690678	0.946679201438133
GO:0009881	photoreceptor activity	1/2115	17/18639	0.0588235294117647	0.518397997496871	0.871065846690678	0.946679201438133
GO:0016805	dipeptidase activity	1/2115	17/18639	0.0588235294117647	0.518397997496871	0.871065846690678	0.946679201438133
GO:0032183	SUMO binding	1/2115	17/18639	0.0588235294117647	0.518397997496871	0.871065846690678	0.946679201438133
GO:0045125	bioactive lipid receptor activity	1/2115	17/18639	0.0588235294117647	0.518397997496871	0.871065846690678	0.946679201438133
GO:1901567	fatty acid derivative binding	1/2115	17/18639	0.0588235294117647	0.518397997496871	0.871065846690678	0.946679201438133
GO:0140034	methylation-dependent protein binding	6/2115	76/18639	0.0789473684210526	0.695744680851064	0.875210900080815	0.950359103990616
GO:0004843	cysteine-type deubiquitinase activity	9/2115	108/18639	0.0833333333333333	0.734397163120567	0.876748028259931	0.951203233432785
GO:0016411	acylglycerol O-acyltransferase activity	2/2115	31/18639	0.0645161290322581	0.56856554564173	0.881455407509253	0.954655856575765
GO:0070273	phosphatidylinositol-4-phosphate binding	2/2115	31/18639	0.0645161290322581	0.56856554564173	0.881455407509253	0.954655856575765
GO:0032393	MHC class I receptor activity	1/2115	18/18639	0.0555555555555556	0.489598108747045	0.885709587118624	0.95678033051986
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/2115	18/18639	0.0555555555555556	0.489598108747045	0.885709587118624	0.95678033051986
GO:1990381	ubiquitin-specific protease binding	1/2115	18/18639	0.0555555555555556	0.489598108747045	0.885709587118624	0.95678033051986
GO:0008173	RNA methyltransferase activity	5/2115	67/18639	0.0746268656716418	0.657669101302001	0.890296429980515	0.960078492967791
GO:0042054	histone methyltransferase activity	5/2115	67/18639	0.0746268656716418	0.657669101302001	0.890296429980515	0.960078492967791
GO:0140030	modification-dependent protein binding	15/2115	173/18639	0.0867052023121387	0.764112655269955	0.895369880335183	0.96414820286864
GO:0008168	methyltransferase activity	18/2115	204/18639	0.0882352941176471	0.777596996245307	0.898532012129379	0.96414820286864
GO:0042800	histone H3K4 methyltransferase activity	1/2115	19/18639	0.0526315789473684	0.463829787234043	0.898690856827239	0.96414820286864
GO:0046527	glucosyltransferase activity	1/2115	19/18639	0.0526315789473684	0.463829787234043	0.898690856827239	0.96414820286864
GO:0120227	acyl-CoA binding	1/2115	19/18639	0.0526315789473684	0.463829787234043	0.898690856827239	0.96414820286864
GO:1990380	K48-linked deubiquitinase activity	1/2115	19/18639	0.0526315789473684	0.463829787234043	0.898690856827239	0.96414820286864
GO:0140416	transcription regulator inhibitor activity	2/2115	33/18639	0.0606060606060606	0.534107027724049	0.902062166678632	0.966936500583602
GO:0001614	purinergic nucleotide receptor activity	1/2115	20/18639	0.05	0.44063829787234	0.910198313208033	0.971593561978636
GO:0001972	retinoic acid binding	1/2115	20/18639	0.05	0.44063829787234	0.910198313208033	0.971593561978636
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/2115	20/18639	0.05	0.44063829787234	0.910198313208033	0.971593561978636
GO:0016502	nucleotide receptor activity	1/2115	20/18639	0.05	0.44063829787234	0.910198313208033	0.971593561978636
GO:0016782	transferase activity, transferring sulphur-containing groups	5/2115	70/18639	0.0714285714285714	0.629483282674772	0.910937502744983	0.971593561978636
GO:0008175	tRNA methyltransferase activity	2/2115	34/18639	0.0588235294117647	0.518397997496871	0.911062972654089	0.971593561978636
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	14/2115	167/18639	0.0838323353293413	0.738794750923684	0.913978528310284	0.973873291442107
GO:0051213	dioxygenase activity	7/2115	93/18639	0.0752688172043011	0.663326469915351	0.914815090763783	0.973935793908382
GO:0004518	nuclease activity	18/2115	209/18639	0.0861244019138756	0.75899419729207	0.918010930172471	0.976507803378023
GO:0005254	chloride channel activity	6/2115	83/18639	0.072289156626506	0.637067418610613	0.920718175270734	0.978556159116264
GO:0004407	histone deacetylase activity	1/2115	22/18639	0.0454545454545455	0.400580270793037	0.929441842563533	0.982821948386439
GO:0005243	gap junction channel activity	1/2115	22/18639	0.0454545454545455	0.400580270793037	0.929441842563533	0.982821948386439
GO:0008970	phospholipase A1 activity	1/2115	22/18639	0.0454545454545455	0.400580270793037	0.929441842563533	0.982821948386439
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/2115	22/18639	0.0454545454545455	0.400580270793037	0.929441842563533	0.982821948386439
GO:0031683	G-protein beta/gamma-subunit complex binding	1/2115	22/18639	0.0454545454545455	0.400580270793037	0.929441842563533	0.982821948386439
GO:0033558	protein lysine deacetylase activity	1/2115	22/18639	0.0454545454545455	0.400580270793037	0.929441842563533	0.982821948386439
GO:0019213	deacetylase activity	2/2115	37/18639	0.0540540540540541	0.476365727429557	0.933623318204058	0.986299993547564
GO:0003887	DNA-directed DNA polymerase activity	1/2115	23/18639	0.0434782608695652	0.383163737280296	0.937457661598723	0.986299993547564
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/2115	23/18639	0.0434782608695652	0.383163737280296	0.937457661598723	0.986299993547564
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/2115	23/18639	0.0434782608695652	0.383163737280296	0.937457661598723	0.986299993547564
GO:0005212	structural constituent of eye lens	1/2115	23/18639	0.0434782608695652	0.383163737280296	0.937457661598723	0.986299993547564
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/2115	23/18639	0.0434782608695652	0.383163737280296	0.937457661598723	0.986299993547564
GO:0030552	cAMP binding	1/2115	24/18639	0.0416666666666667	0.367198581560284	0.944563218416444	0.992941351349612
GO:0160215	deacylase activity	4/2115	65/18639	0.0615384615384615	0.542324058919804	0.946548774719283	0.994193847272267
GO:0000030	mannosyltransferase activity	1/2115	25/18639	0.04	0.352510638297872	0.95086183743601	0.995383796379502
GO:0017056	structural constituent of nuclear pore	1/2115	25/18639	0.04	0.352510638297872	0.95086183743601	0.995383796379502
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/2115	25/18639	0.04	0.352510638297872	0.95086183743601	0.995383796379502
GO:0019707	protein-cysteine S-acyltransferase activity	1/2115	25/18639	0.04	0.352510638297872	0.95086183743601	0.995383796379502
GO:0019865	immunoglobulin binding	1/2115	26/18639	0.0384615384615385	0.338952536824877	0.956445119579711	0.99999999864303
GO:0008374	O-acyltransferase activity	3/2115	55/18639	0.0545454545454545	0.480696324951644	0.957239111833968	0.99999999864303
GO:0016279	protein-lysine N-methyltransferase activity	4/2115	69/18639	0.0579710144927536	0.510884983040395	0.961366853614649	0.99999999864303
GO:0015252	proton channel activity	1/2115	27/18639	0.037037037037037	0.326398739164697	0.961394271897387	0.99999999864303
GO:0016278	lysine N-methyltransferase activity	4/2115	70/18639	0.0571428571428571	0.503586626139818	0.964423177909781	0.99999999864303
GO:0005242	inward rectifier potassium channel activity	1/2115	28/18639	0.0357142857142857	0.314741641337386	0.965781286454502	0.99999999864303
GO:0141052	histone H3 demethylase activity	1/2115	28/18639	0.0357142857142857	0.314741641337386	0.965781286454502	0.99999999864303
GO:0004181	metallocarboxypeptidase activity	1/2115	29/18639	0.0344827586206897	0.303888481291269	0.969669985565175	0.99999999864303
GO:0010484	histone H3 acetyltransferase activity	1/2115	29/18639	0.0344827586206897	0.303888481291269	0.969669985565175	0.99999999864303
GO:0003730	mRNA 3'-UTR binding	21/2115	262/18639	0.0801526717557252	0.706366737047263	0.969788665956245	0.99999999864303
GO:0008170	N-methyltransferase activity	6/2115	98/18639	0.0612244897959184	0.539557099435519	0.972524118658151	0.99999999864303
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	3/2115	60/18639	0.05	0.44063829787234	0.97278080059382	0.99999999864303
GO:0032452	histone demethylase activity	1/2115	30/18639	0.0333333333333333	0.293758865248227	0.973116948516795	0.99999999864303
GO:0140457	protein demethylase activity	1/2115	31/18639	0.032258064516129	0.284282772820865	0.976172333217046	0.99999999864303
GO:0008188	neuropeptide receptor activity	2/2115	48/18639	0.0416666666666667	0.367198581560284	0.978078695450948	0.99999999864303
GO:0010485	histone H4 acetyltransferase activity	1/2115	35/18639	0.0285714285714286	0.251793313069909	0.985295054998059	0.99999999864303
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/2115	36/18639	0.0277777777777778	0.244799054373522	0.986966790037787	0.99999999864303
GO:0016409	palmitoyltransferase activity	1/2115	36/18639	0.0277777777777778	0.244799054373522	0.986966790037787	0.99999999864303
GO:0098960	postsynaptic neurotransmitter receptor activity	3/2115	69/18639	0.0434782608695652	0.383163737280296	0.98823993228917	0.99999999864303
GO:0008528	G protein-coupled peptide receptor activity	7/2115	122/18639	0.0573770491803279	0.505650505755145	0.988563960939972	0.99999999864303
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	2/2115	56/18639	0.0357142857142857	0.314741641337386	0.990459842699961	0.99999999864303
GO:0032451	demethylase activity	1/2115	40/18639	0.025	0.22031914893617	0.991957827350237	0.99999999864303
GO:0140098	catalytic activity, acting on RNA	30/2115	387/18639	0.0775193798449612	0.683160151740063	0.992675066716167	0.99999999864303
GO:0001653	peptide receptor activity	7/2115	128/18639	0.0546875	0.481948138297872	0.992753866426719	0.99999999864303
GO:0016755	aminoacyltransferase activity	40/2115	496/18639	0.0806451612903226	0.710706932052162	0.99390599306361	0.99999999864303
GO:0005245	voltage-gated calcium channel activity	1/2115	43/18639	0.0232558139534884	0.204948045522019	0.994401348461517	0.99999999864303
GO:0046873	metal ion transmembrane transporter activity	35/2115	450/18639	0.0777777777777778	0.685437352245863	0.995424730631517	0.99999999864303
GO:0015085	calcium ion transmembrane transporter activity	8/2115	147/18639	0.054421768707483	0.47960631060935	0.995546367230678	0.99999999864303
GO:0019787	ubiquitin-like protein transferase activity	37/2115	479/18639	0.0772442588726514	0.68073557500111	0.996821108543887	0.99999999864303
GO:0005249	voltage-gated potassium channel activity	4/2115	98/18639	0.0408163265306122	0.359704732957013	0.996985441512661	0.99999999864303
GO:0004842	ubiquitin-protein transferase activity	34/2115	449/18639	0.0757238307349666	0.667336397668578	0.997104079697215	0.99999999864303
GO:0061630	ubiquitin protein ligase activity	25/2115	353/18639	0.0708215297450425	0.624133566391417	0.997364636751169	0.99999999864303
GO:0005272	sodium channel activity	1/2115	51/18639	0.0196078431372549	0.172799332498957	0.997869352171648	0.99999999864303
GO:0061659	ubiquitin-like protein ligase activity	26/2115	372/18639	0.0698924731182796	0.61594600777854	0.998290342759525	0.99999999864303
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/2115	53/18639	0.0188679245283019	0.166278602970694	0.998326642475027	0.99999999864303
GO:0005267	potassium channel activity	5/2115	124/18639	0.0403225806451613	0.355353466026081	0.998948749001348	0.99999999864303
GO:0140101	catalytic activity, acting on a tRNA	6/2115	139/18639	0.0431654676258993	0.380407163630798	0.999018188441604	0.99999999864303
GO:0030594	neurotransmitter receptor activity	3/2115	97/18639	0.0309278350515464	0.272559771879798	0.999259600712324	0.99999999864303
GO:0005244	voltage-gated monoatomic ion channel activity	8/2115	173/18639	0.046242774566474	0.407526749477309	0.999434619753811	0.99999999864303
GO:0005262	calcium channel activity	5/2115	131/18639	0.0381679389312977	0.336365112879649	0.999446192584058	0.99999999864303
GO:0022824	transmitter-gated monoatomic ion channel activity	1/2115	63/18639	0.0158730158730159	0.139885173927727	0.999500202574359	0.99999999864303
GO:0022835	transmitter-gated channel activity	1/2115	63/18639	0.0158730158730159	0.139885173927727	0.999500202574359	0.99999999864303
GO:0022832	voltage-gated channel activity	8/2115	175/18639	0.0457142857142857	0.402869300911854	0.999520805973187	0.99999999864303
GO:0099094	ligand-gated monoatomic cation channel activity	5/2115	136/18639	0.0367647058823529	0.323998748435544	0.999651855170593	0.99999999864303
GO:0022843	voltage-gated monoatomic cation channel activity	5/2115	143/18639	0.034965034965035	0.308138669840798	0.999819721053545	0.99999999864303
GO:0015079	potassium ion transmembrane transporter activity	6/2115	160/18639	0.0375	0.330478723404255	0.999849647726424	0.99999999864303
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/2115	73/18639	0.0136986301369863	0.120722821334888	0.999850824014629	0.99999999864303
GO:0030527	structural constituent of chromatin	2/2115	98/18639	0.0204081632653061	0.179852366478506	0.999901429564959	0.99999999864303
GO:0022836	gated channel activity	16/2115	318/18639	0.050314465408805	0.443409607921852	0.999975098552621	0.99999999864303
GO:0005216	monoatomic ion channel activity	26/2115	448/18639	0.0580357142857143	0.511455167173252	0.999983529126472	0.99999999864303
GO:0003823	antigen binding	5/2115	174/18639	0.028735632183908	0.253240401076058	0.999991130030312	0.99999999864303
GO:0045182	translation regulator activity	17/2115	356/18639	0.047752808988764	0.42083432942864	0.999996315478247	0.99999999864303
GO:0015276	ligand-gated monoatomic ion channel activity	5/2115	186/18639	0.0268817204301075	0.236902310684054	0.999997331773296	0.99999999864303
GO:0022834	ligand-gated channel activity	5/2115	188/18639	0.0265957446808511	0.234382073336351	0.9999978194713	0.99999999864303
GO:0005261	monoatomic cation channel activity	14/2115	341/18639	0.0410557184750733	0.361814438135646	0.999999539441024	0.99999999864303
GO:0030371	translation repressor activity	9/2115	329/18639	0.027355623100304	0.241078704003104	0.99999999864303	0.99999999864303