ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	104/2245	175/18639	0.594285714285714	4.93402736239262	6.78277388065612e-51	8.45811902917819e-48
GO:0045296	cadherin binding	90/2245	334/18639	0.269461077844311	2.2371870957417	6.43660161793771e-14	4.01322110878416e-11
GO:0019843	rRNA binding	29/2245	65/18639	0.446153846153846	3.70416995031694	5.81789758991588e-11	2.41830609820837e-08
GO:0009055	electron transfer activity	39/2245	116/18639	0.336206896551724	2.79134091083634	9.57566560902366e-10	2.98521375361313e-07
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	28/2245	68/18639	0.411764705882353	3.41865583649941	1.19963773593938e-09	2.99189651343282e-07
GO:0048027	mRNA 5'-UTR binding	14/2245	24/18639	0.583333333333333	4.84309576837417	7.84422770762285e-08	1.63029199190095e-05
GO:0051087	protein-folding chaperone binding	38/2245	134/18639	0.283582089552239	2.35442608782369	2.67155714508438e-07	4.75918822845747e-05
GO:0003697	single-stranded DNA binding	35/2245	121/18639	0.289256198347107	2.40153509175578	4.64632158739303e-07	6.56039657182083e-05
GO:0140104	molecular carrier activity	58/2245	249/18639	0.232931726907631	1.93390399012531	4.73484916971832e-07	6.56039657182083e-05
GO:0022853	active monoatomic ion transmembrane transporter activity	34/2245	118/18639	0.288135593220339	2.39223132384583	7.44616297910534e-07	9.28536523494436e-05
GO:0055105	ubiquitin-protein transferase inhibitor activity	10/2245	15/18639	0.666666666666667	5.53496659242762	1.06554954129272e-06	0.000120794570726547
GO:0051082	unfolded protein binding	34/2245	121/18639	0.28099173553719	2.3329198034199	1.40474966105151e-06	0.000142873198876106
GO:0031720	haptoglobin binding	8/2245	10/18639	0.8	6.64195991091314	1.57338495616843e-06	0.000142873198876106
GO:0008017	microtubule binding	61/2245	276/18639	0.221014492753623	1.83496175075046	1.60402949820809e-06	0.000142873198876106
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	21/2245	60/18639	0.35	2.9058574610245	3.33460846059554e-06	0.000277217116690843
GO:1990948	ubiquitin ligase inhibitor activity	8/2245	11/18639	0.727272727272727	6.0381453735574	5.15515547567633e-06	0.000401779929885524
GO:0003954	NADH dehydrogenase activity	17/2245	44/18639	0.386363636363636	3.20776472970237	6.1426214644127e-06	0.000450579350948391
GO:0030515	snoRNA binding	14/2245	32/18639	0.4375	3.63232182628062	7.35982334867851e-06	0.00050987220643345
GO:0008137	NADH dehydrogenase (ubiquinone) activity	16/2245	41/18639	0.390243902439024	3.23998044434787	9.88555104878087e-06	0.000648804324096303
GO:0003684	damaged DNA binding	23/2245	74/18639	0.310810810810811	2.58049118160477	1.13849627539862e-05	0.000686704632196145
GO:0015399	primary active transmembrane transporter activity	40/2245	166/18639	0.240963855421687	2.00059033461239	1.15643923625654e-05	0.000686704632196145
GO:0140297	DNA-binding transcription factor binding	91/2245	488/18639	0.186475409836066	1.54820274562781	1.2728737198064e-05	0.000720501926473127
GO:0004129	cytochrome-c oxidase activity	9/2245	15/18639	0.6	4.98146993318486	1.32891293575637e-05	0.000720501926473127
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	15/2245	38/18639	0.394736842105263	3.27728285077951	1.58872701517241e-05	0.000825476078299998
GO:0000287	magnesium ion binding	50/2245	230/18639	0.217391304347826	1.80488041057422	2.1562067391244e-05	0.00106797052599269
GO:0016829	lyase activity	45/2245	200/18639	0.225	1.86805122494432	2.22672282885405e-05	0.00106797052599269
GO:0003713	transcription coactivator activity	54/2245	256/18639	0.2109375	1.7512980233853	2.52974962116664e-05	0.00112721699102651
GO:0000175	3'-5'-RNA exonuclease activity	14/2245	35/18639	0.4	3.32097995545657	2.54856507214536e-05	0.00112721699102651
GO:0003688	DNA replication origin binding	9/2245	16/18639	0.5625	4.6701280623608	2.71182916846795e-05	0.00112721699102651
GO:0016675	oxidoreductase activity, acting on a heme group of donors	9/2245	16/18639	0.5625	4.6701280623608	2.71182916846795e-05	0.00112721699102651
GO:0004532	RNA exonuclease activity	15/2245	40/18639	0.375	3.11341870824053	3.2656240203146e-05	0.00131362359784913
GO:0015631	tubulin binding	73/2245	385/18639	0.18961038961039	1.57423075810604	5.09626003406319e-05	0.001985948832024
GO:0070182	DNA polymerase binding	10/2245	21/18639	0.476190476190476	3.95354756601973	6.29483570065324e-05	0.00237868488445897
GO:0005344	oxygen carrier activity	8/2245	14/18639	0.571428571428571	4.74425707922367	6.70182378141703e-05	0.00245799242806677
GO:0015078	proton transmembrane transporter activity	41/2245	185/18639	0.221621621621622	1.84000240775296	7.24926356854798e-05	0.00258280904856552
GO:0004601	peroxidase activity	18/2245	57/18639	0.315789473684211	2.62182628062361	7.91034793186609e-05	0.00274005663084361
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	18/2245	58/18639	0.310344827586207	2.57662237923355	0.000101907456846374	0.00334417364966917
GO:0017116	single-stranded DNA helicase activity	18/2245	58/18639	0.310344827586207	2.57662237923355	0.000101907456846374	0.00334417364966917
GO:0004527	exonuclease activity	23/2245	84/18639	0.273809523809524	2.27328985046134	0.000105328310430894	0.00336780520788011
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	18/2245	59/18639	0.305084745762712	2.53295081348382	0.000130300350206254	0.00406211341767996
GO:0055106	ubiquitin-protein transferase regulator activity	13/2245	36/18639	0.361111111111111	2.99810690423163	0.000170445566365668	0.00518403954287775
GO:0031625	ubiquitin protein ligase binding	58/2245	302/18639	0.19205298013245	1.59451024351392	0.000203105579674025	0.0060303013774645
GO:0140597	protein carrier chaperone	40/2245	188/18639	0.212765957446809	1.76647869971094	0.000221696337958122	0.00631230696896165
GO:0140097	catalytic activity, acting on DNA	63/2245	336/18639	0.1875	1.55670935412027	0.000222727751912039	0.00631230696896165
GO:0016887	ATP hydrolysis activity	75/2245	417/18639	0.179856115107914	1.49324638284918	0.000230947606102647	0.00639981477355556
GO:0016835	carbon-oxygen lyase activity	21/2245	79/18639	0.265822784810127	2.20698035014519	0.000322985954569543	0.00856661463041
GO:0008408	3'-5' exonuclease activity	17/2245	58/18639	0.293103448275862	2.43347669149835	0.000338697560760162	0.00856661463041
GO:0016860	intramolecular oxidoreductase activity	16/2245	53/18639	0.30188679245283	2.50639996638232	0.000347066861505341	0.00856661463041
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	15/2245	48/18639	0.3125	2.59451559020045	0.00034786462781114	0.00856661463041
GO:0036121	double-stranded DNA helicase activity	15/2245	48/18639	0.3125	2.59451559020045	0.00034786462781114	0.00856661463041
GO:0003678	DNA helicase activity	20/2245	74/18639	0.27027027027027	2.24390537530849	0.000350358737891668	0.00856661463041
GO:0044389	ubiquitin-like protein ligase binding	60/2245	322/18639	0.186335403726708	1.54704035192076	0.00036724182966587	0.00880674156910268
GO:0000217	DNA secondary structure binding	13/2245	39/18639	0.333333333333333	2.76748329621381	0.000423269186202508	0.00995880519234959
GO:0003712	transcription coregulator activity	85/2245	495/18639	0.171717171717172	1.42567321320105	0.00044236449244025	0.0102153430013517
GO:0140713	histone chaperone activity	35/2245	164/18639	0.213414634146341	1.77186430550274	0.000499913765888699	0.0113344084738765
GO:0016651	oxidoreductase activity, acting on NAD(P)H	22/2245	88/18639	0.25	2.07561247216036	0.000594928866654008	0.0131071850022864
GO:0070034	telomerase RNA binding	9/2245	22/18639	0.409090909090909	3.39645677262604	0.000599125537394003	0.0131071850022864
GO:0016853	isomerase activity	37/2245	180/18639	0.205555555555556	1.70661469933185	0.000745005100162969	0.0160176096535038
GO:0061749	forked DNA-dependent helicase activity	14/2245	47/18639	0.297872340425532	2.47307017959532	0.000927825862971812	0.0196101500190822
GO:0031491	nucleosome binding	19/2245	74/18639	0.256756756756757	2.13171010654307	0.000968015020113286	0.0198590140891398
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	7/2245	15/18639	0.466666666666667	3.87447661469933	0.00097145137084004	0.0198590140891398
GO:0004540	RNA nuclease activity	27/2245	121/18639	0.223140495867769	1.85261278506875	0.00103647776733558	0.0206472976915432
GO:0097718	disordered domain specific binding	10/2245	28/18639	0.357142857142857	2.9651606745148	0.00105734931753321	0.0206472976915432
GO:0004518	nuclease activity	41/2245	209/18639	0.196172248803828	1.62871026523588	0.00105968488553229	0.0206472976915432
GO:0016209	antioxidant activity	21/2245	86/18639	0.244186046511628	2.02734241466826	0.00108760684859206	0.0208653190799123
GO:0009378	four-way junction helicase activity	14/2245	48/18639	0.291666666666667	2.42154788418708	0.00116663343039091	0.0220423013287495
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	6/2245	12/18639	0.5	4.15122494432071	0.00146706026877395	0.0269032963994282
GO:1990247	N6-methyladenosine-containing RNA reader activity	6/2245	12/18639	0.5	4.15122494432071	0.00146706026877395	0.0269032963994282
GO:0004386	helicase activity	32/2245	155/18639	0.206451612903226	1.71405417055823	0.00151765355380706	0.0274277388637304
GO:0180051	translation factor activity	20/2245	84/18639	0.238095238095238	1.97677378300986	0.00196049992489016	0.0349249058048291
GO:0043021	ribonucleoprotein complex binding	35/2245	177/18639	0.19774011299435	1.64172737910989	0.00205321165349885	0.0360613370691981
GO:0022804	active transmembrane transporter activity	76/2245	457/18639	0.166301969365427	1.38071376703884	0.00212540188379152	0.0368107798484449
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	6/2245	13/18639	0.461538461538462	3.83189994860374	0.00244808778297205	0.0412535873698128
GO:0004535	poly(A)-specific ribonuclease activity	6/2245	13/18639	0.461538461538462	3.83189994860374	0.00244808778297205	0.0412535873698128
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	60/2245	349/18639	0.171919770773639	1.42735528171486	0.00277283060610341	0.0461029302108127
GO:1990518	single-stranded 3'-5' DNA helicase activity	13/2245	47/18639	0.276595744680851	2.29642230962422	0.00291703298369579	0.0475283641172831
GO:0140517	protein-RNA adaptor activity	8/2245	22/18639	0.363636363636364	3.0190726867787	0.00293479072737033	0.0475283641172831
GO:0098641	cadherin binding involved in cell-cell adhesion	7/2245	18/18639	0.388888888888889	3.22873051224944	0.00346469934354438	0.0553907702743569
GO:0043138	3'-5' DNA helicase activity	13/2245	48/18639	0.270833333333333	2.24858017817372	0.00356718138920902	0.0563072809157424
GO:0033204	ribonuclease P RNA binding	5/2245	10/18639	0.5	4.15122494432071	0.00376708222948418	0.0572872139044729
GO:0050815	phosphoserine residue binding	5/2245	10/18639	0.5	4.15122494432071	0.00376708222948418	0.0572872139044729
GO:0097177	mitochondrial ribosome binding	5/2245	10/18639	0.5	4.15122494432071	0.00376708222948418	0.0572872139044729
GO:0051287	NAD binding	14/2245	54/18639	0.259259259259259	2.1524870081663	0.00392740277429683	0.0590056778258813
GO:0008135	translation factor activity, RNA binding	19/2245	83/18639	0.228915662650602	1.90056081788177	0.00401509680726377	0.059605068079261
GO:0019205	nucleobase-containing compound kinase activity	12/2245	44/18639	0.272727272727273	2.26430451508402	0.00472676901243622	0.0693444818647996
GO:0003689	DNA clamp loader activity	31/2245	160/18639	0.19375	1.60859966592428	0.00489416725926638	0.0709654252593625
GO:0019206	nucleoside kinase activity	5/2245	11/18639	0.454545454545455	3.77384085847337	0.00622581014038022	0.0882225596028879
GO:0050786	RAGE receptor binding	5/2245	11/18639	0.454545454545455	3.77384085847337	0.00622581014038022	0.0882225596028879
GO:0008094	ATP-dependent activity, acting on DNA	38/2245	210/18639	0.180952380952381	1.5023480750875	0.00660347322926091	0.0925228215380714
GO:0031072	heat shock protein binding	26/2245	131/18639	0.198473282442748	1.64781448171509	0.00684398877066639	0.0933836106944945
GO:0016769	transferase activity, transferring nitrogenous groups	9/2245	30/18639	0.3	2.49073496659243	0.00705780651220517	0.0933836106944945
GO:0017056	structural constituent of nuclear pore	8/2245	25/18639	0.32	2.65678396436526	0.00713878628559482	0.0933836106944945
GO:0000510	H3-H4 histone complex chaperone activity	29/2245	151/18639	0.19205298013245	1.59451024351392	0.00718911517776381	0.0933836106944945
GO:0140584	chromatin extrusion motor activity	29/2245	151/18639	0.19205298013245	1.59451024351392	0.00718911517776381	0.0933836106944945
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	29/2245	151/18639	0.19205298013245	1.59451024351392	0.00718911517776381	0.0933836106944945
GO:0140849	ATP-dependent H2AZ histone chaperone activity	29/2245	151/18639	0.19205298013245	1.59451024351392	0.00718911517776381	0.0933836106944945
GO:0140658	ATP-dependent chromatin remodeler activity	30/2245	158/18639	0.189873417721519	1.57641453581799	0.00747671805095826	0.0961182207169582
GO:0015616	DNA translocase activity	29/2245	152/18639	0.190789473684211	1.58402004454343	0.00788824332485766	0.0993599942030051
GO:0140674	ATP-dependent histone chaperone activity	29/2245	152/18639	0.190789473684211	1.58402004454343	0.00788824332485766	0.0993599942030051
GO:0042393	histone binding	43/2245	247/18639	0.174089068825911	1.44536577008737	0.00814832785522815	0.101609648354695
GO:0061775	cohesin loader activity	29/2245	153/18639	0.189542483660131	1.57366697235687	0.00864251273316346	0.106705082953018
GO:0045309	protein phosphorylated amino acid binding	14/2245	59/18639	0.23728813559322	1.97007285493186	0.00906611209879534	0.110837664580371
GO:0031492	nucleosomal DNA binding	11/2245	42/18639	0.261904761904762	2.17445116131085	0.00927055353251561	0.111157502452375
GO:0051879	Hsp90 protein binding	11/2245	42/18639	0.261904761904762	2.17445116131085	0.00927055353251561	0.111157502452375
GO:0004526	ribonuclease P activity	5/2245	12/18639	0.416666666666667	3.45935412026726	0.00962491719152756	0.114307349884142
GO:0017069	snRNA binding	13/2245	54/18639	0.240740740740741	1.99873793615442	0.0103276910267517	0.121496516135466
GO:0031369	translation initiation factor binding	9/2245	32/18639	0.28125	2.3350640311804	0.011091072132304	0.129257635037226
GO:0140098	catalytic activity, acting on RNA	62/2245	387/18639	0.160206718346253	1.33010825089346	0.0114672833745072	0.130873298088793
GO:0004549	tRNA-specific ribonuclease activity	6/2245	17/18639	0.352941176470588	2.93027643128521	0.0115445571690194	0.130873298088793
GO:1990226	histone methyltransferase binding	6/2245	17/18639	0.352941176470588	2.93027643128521	0.0115445571690194	0.130873298088793
GO:0098632	cell-cell adhesion mediator activity	13/2245	55/18639	0.236363636363636	1.96239724640615	0.0120708157680319	0.135606371736359
GO:0043531	ADP binding	10/2245	38/18639	0.263157894736842	2.18485523385301	0.0124010271023252	0.138072149969638
GO:0030145	manganese ion binding	15/2245	68/18639	0.220588235294118	1.83142276955326	0.0139518029228188	0.149116213204473
GO:0051219	phosphoprotein binding	19/2245	93/18639	0.204301075268817	1.69619943961491	0.014065157099023	0.149116213204473
GO:0005542	folic acid binding	5/2245	13/18639	0.384615384615385	3.19324995716978	0.0141104355718747	0.149116213204473
GO:0019104	DNA N-glycosylase activity	5/2245	13/18639	0.384615384615385	3.19324995716978	0.0141104355718747	0.149116213204473
GO:0043560	insulin receptor substrate binding	5/2245	13/18639	0.384615384615385	3.19324995716978	0.0141104355718747	0.149116213204473
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	5/2245	13/18639	0.384615384615385	3.19324995716978	0.0141104355718747	0.149116213204473
GO:0000400	four-way junction DNA binding	6/2245	18/18639	0.333333333333333	2.76748329621381	0.015584486081757	0.161948784532925
GO:0070628	proteasome binding	6/2245	18/18639	0.333333333333333	2.76748329621381	0.015584486081757	0.161948784532925
GO:0016874	ligase activity	30/2245	167/18639	0.179640718562874	1.4914580638278	0.016018344700507	0.161967136193802
GO:0003743	translation initiation factor activity	12/2245	51/18639	0.235294117647059	1.95351762085681	0.0161057938155825	0.161967136193802
GO:0016830	carbon-carbon lyase activity	12/2245	51/18639	0.235294117647059	1.95351762085681	0.0161057938155825	0.161967136193802
GO:0030544	Hsp70 protein binding	12/2245	51/18639	0.235294117647059	1.95351762085681	0.0161057938155825	0.161967136193802
GO:0016831	carboxy-lyase activity	9/2245	34/18639	0.264705882352941	2.19770732346391	0.0166390561193604	0.163377188825531
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	9/2245	34/18639	0.264705882352941	2.19770732346391	0.0166390561193604	0.163377188825531
GO:0019825	oxygen binding	9/2245	34/18639	0.264705882352941	2.19770732346391	0.0166390561193604	0.163377188825531
GO:0098631	cell adhesion mediator activity	16/2245	76/18639	0.210526315789474	1.74788418708241	0.0175472048127252	0.170948159386471
GO:0003727	single-stranded RNA binding	18/2245	89/18639	0.202247191011236	1.67914716848928	0.0182559764812201	0.176474439318461
GO:0030276	clathrin binding	11/2245	46/18639	0.239130434782609	1.98536845163165	0.0184507948356903	0.176985701231583
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	23/2245	122/18639	0.188524590163934	1.56521596261273	0.0190114887365502	0.180971957667772
GO:0050699	WW domain binding	7/2245	24/18639	0.291666666666667	2.42154788418708	0.0197383873421811	0.185156395887261
GO:0051540	metal cluster binding	16/2245	77/18639	0.207792207792208	1.72518439244497	0.0197480358083446	0.185156395887261
GO:0008301	DNA binding, bending	6/2245	19/18639	0.315789473684211	2.62182628062361	0.0205056382882087	0.189411340336268
GO:0008574	plus-end-directed microtubule motor activity	6/2245	19/18639	0.315789473684211	2.62182628062361	0.0205056382882087	0.189411340336268
GO:0016877	ligase activity, forming carbon-sulfur bonds	10/2245	41/18639	0.24390243902439	2.02498777771742	0.0210788365325007	0.191863570481959
GO:0061650	ubiquitin-like protein conjugating enzyme activity	10/2245	41/18639	0.24390243902439	2.02498777771742	0.0210788365325007	0.191863570481959
GO:0070063	RNA polymerase binding	13/2245	59/18639	0.220338983050847	1.82935336529387	0.0213945144538201	0.193325793651548
GO:0019887	protein kinase regulator activity	42/2245	255/18639	0.164705882352941	1.36746233459976	0.0216266533863477	0.194017530739393
GO:0016922	nuclear receptor binding	25/2245	137/18639	0.182481751824818	1.51504560011705	0.0218912592831834	0.19498857375807
GO:0030957	Tat protein binding	4/2245	10/18639	0.4	3.32097995545657	0.0242060122839609	0.209617342486801
GO:0031996	thioesterase binding	4/2245	10/18639	0.4	3.32097995545657	0.0242060122839609	0.209617342486801
GO:0032356	oxidized DNA binding	4/2245	10/18639	0.4	3.32097995545657	0.0242060122839609	0.209617342486801
GO:0098505	G-rich strand telomeric DNA binding	4/2245	10/18639	0.4	3.32097995545657	0.0242060122839609	0.209617342486801
GO:0008483	transaminase activity	7/2245	25/18639	0.28	2.3246859688196	0.0246382321975203	0.210437503769231
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	7/2245	25/18639	0.28	2.3246859688196	0.0246382321975203	0.210437503769231
GO:0003925	G protein activity	12/2245	54/18639	0.222222222222222	1.84498886414254	0.0248355160678147	0.210679513854183
GO:0043022	ribosome binding	21/2245	112/18639	0.1875	1.55670935412027	0.0256043917790863	0.215734301003518
GO:0043539	protein serine/threonine kinase activator activity	15/2245	73/18639	0.205479452054795	1.70598285383043	0.0258291939734325	0.216167818019264
GO:0031386	protein tag activity	5/2245	15/18639	0.333333333333333	2.76748329621381	0.0268304583825753	0.220115668441259
GO:0061578	K63-linked deubiquitinase activity	5/2245	15/18639	0.333333333333333	2.76748329621381	0.0268304583825753	0.220115668441259
GO:0141047	molecular tag activity	5/2245	15/18639	0.333333333333333	2.76748329621381	0.0268304583825753	0.220115668441259
GO:0048306	calcium-dependent protein binding	16/2245	80/18639	0.2	1.66048997772829	0.0276189853231683	0.222808573883519
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	13/2245	61/18639	0.213114754098361	1.76937456643178	0.0276947305147919	0.222808573883519
GO:0016836	hydro-lyase activity	13/2245	61/18639	0.213114754098361	1.76937456643178	0.0276947305147919	0.222808573883519
GO:0016763	pentosyltransferase activity	11/2245	49/18639	0.224489795918367	1.86381528112359	0.0288404937782873	0.228098205271057
GO:0060590	ATPase regulator activity	11/2245	49/18639	0.224489795918367	1.86381528112359	0.0288404937782873	0.228098205271057
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	10/2245	43/18639	0.232558139534884	1.93080229968405	0.0289009754874314	0.228098205271057
GO:0003777	microtubule motor activity	14/2245	68/18639	0.205882352941176	1.7093279182497	0.0301535642175274	0.23623043679707
GO:0004529	DNA exonuclease activity	7/2245	26/18639	0.269230769230769	2.23527497001885	0.0303102404871942	0.23623043679707
GO:0030170	pyridoxal phosphate binding	12/2245	56/18639	0.214285714285714	1.77909640470888	0.0323155245065318	0.24710963014686
GO:0051059	NF-kappaB binding	8/2245	32/18639	0.25	2.07561247216036	0.0324420119143104	0.24710963014686
GO:0140142	nucleocytoplasmic carrier activity	8/2245	32/18639	0.25	2.07561247216036	0.0324420119143104	0.24710963014686
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	6/2245	21/18639	0.285714285714286	2.37212853961184	0.0332733153379711	0.24710963014686
GO:0042162	telomeric DNA binding	9/2245	38/18639	0.236842105263158	1.96636971046771	0.0333723637143089	0.24710963014686
GO:0002039	p53 binding	14/2245	69/18639	0.202898550724638	1.68455504986927	0.0337822080109076	0.24710963014686
GO:0005225	volume-sensitive anion channel activity	4/2245	11/18639	0.363636363636364	3.0190726867787	0.0344804135088642	0.24710963014686
GO:0005536	D-glucose binding	4/2245	11/18639	0.363636363636364	3.0190726867787	0.0344804135088642	0.24710963014686
GO:0010854	adenylate cyclase regulator activity	4/2245	11/18639	0.363636363636364	3.0190726867787	0.0344804135088642	0.24710963014686
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	4/2245	11/18639	0.363636363636364	3.0190726867787	0.0344804135088642	0.24710963014686
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	4/2245	11/18639	0.363636363636364	3.0190726867787	0.0344804135088642	0.24710963014686
GO:0034511	U3 snoRNA binding	4/2245	11/18639	0.363636363636364	3.0190726867787	0.0344804135088642	0.24710963014686
GO:0045294	alpha-catenin binding	4/2245	11/18639	0.363636363636364	3.0190726867787	0.0344804135088642	0.24710963014686
GO:0048407	platelet-derived growth factor binding	4/2245	11/18639	0.363636363636364	3.0190726867787	0.0344804135088642	0.24710963014686
GO:0044325	transmembrane transporter binding	24/2245	136/18639	0.176470588235294	1.4651382156426	0.0348300361345506	0.248188886055912
GO:0031435	mitogen-activated protein kinase kinase kinase binding	5/2245	16/18639	0.3125	2.59451559020045	0.0352519803453845	0.24835717226381
GO:0034450	ubiquitin-ubiquitin ligase activity	5/2245	16/18639	0.3125	2.59451559020045	0.0352519803453845	0.24835717226381
GO:0051536	iron-sulfur cluster binding	15/2245	76/18639	0.197368421052632	1.63864142538975	0.0358673957417309	0.251273272415385
GO:0015932	nucleobase-containing compound transmembrane transporter activity	12/2245	57/18639	0.210526315789474	1.74788418708241	0.0366051165499744	0.25351481785892
GO:0070279	vitamin B6 binding	12/2245	57/18639	0.210526315789474	1.74788418708241	0.0366051165499744	0.25351481785892
GO:0001671	ATPase activator activity	7/2245	27/18639	0.259259259259259	2.1524870081663	0.036797259047686	0.25351481785892
GO:0097110	scaffold protein binding	14/2245	70/18639	0.2	1.66048997772829	0.0377160686490939	0.25841723959022
GO:0019207	kinase regulator activity	45/2245	287/18639	0.156794425087108	1.30177785710406	0.0383116700263736	0.260602052076187
GO:0140416	transcription regulator inhibitor activity	8/2245	33/18639	0.242424242424242	2.01271512451913	0.0384529090473282	0.260602052076187
GO:0008649	rRNA methyltransferase activity	6/2245	22/18639	0.272727272727273	2.26430451508402	0.041231299081083	0.277921242995192
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	23/2245	132/18639	0.174242424242424	1.44663899574813	0.0433485806872692	0.290621936113036
GO:0051537	2 iron, 2 sulfur cluster binding	7/2245	28/18639	0.25	2.07561247216036	0.0441348137526801	0.291816503376222
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	10/2245	46/18639	0.217391304347826	1.80488041057422	0.0441766006641429	0.291816503376222
GO:0004857	enzyme inhibitor activity	62/2245	416/18639	0.149038461538462	1.23738435840329	0.0442940882441611	0.291816503376222
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	9/2245	40/18639	0.225	1.86805122494432	0.0450339008059991	0.291816503376222
GO:0071949	FAD binding	9/2245	40/18639	0.225	1.86805122494432	0.0450339008059991	0.291816503376222
GO:0140662	ATP-dependent protein folding chaperone	9/2245	40/18639	0.225	1.86805122494432	0.0450339008059991	0.291816503376222
GO:0090482	vitamin transmembrane transporter activity	8/2245	34/18639	0.235294117647059	1.95351762085681	0.0451648637943953	0.291816503376222
GO:0004859	phospholipase inhibitor activity	4/2245	12/18639	0.333333333333333	2.76748329621381	0.0469081616675326	0.298441212241904
GO:0005049	nuclear export signal receptor activity	4/2245	12/18639	0.333333333333333	2.76748329621381	0.0469081616675326	0.298441212241904
GO:0043047	single-stranded telomeric DNA binding	4/2245	12/18639	0.333333333333333	2.76748329621381	0.0469081616675326	0.298441212241904
GO:0050660	flavin adenine dinucleotide binding	16/2245	86/18639	0.186046511627907	1.54464183974724	0.0499889011802525	0.31202132931358
GO:0042826	histone deacetylase binding	22/2245	127/18639	0.173228346456693	1.43821966574891	0.0500171049238982	0.31202132931358
GO:0004602	glutathione peroxidase activity	6/2245	23/18639	0.260869565217391	2.16585649268907	0.0502912944375823	0.31202132931358
GO:0140102	catalytic activity, acting on a rRNA	6/2245	23/18639	0.260869565217391	2.16585649268907	0.0502912944375823	0.31202132931358
GO:0005504	fatty acid binding	10/2245	47/18639	0.212765957446809	1.76647869971094	0.0502937347169443	0.31202132931358
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	12/2245	60/18639	0.2	1.66048997772829	0.0518504360017181	0.32008660244625
GO:0030695	GTPase regulator activity	71/2245	489/18639	0.14519427402863	1.20546818424037	0.0538988437080496	0.331092897063734
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	11/2245	54/18639	0.203703703703704	1.69123979213066	0.0544703712744263	0.332963494996125
GO:0060589	nucleoside-triphosphatase regulator activity	71/2245	490/18639	0.144897959183673	1.20300804508886	0.0558564166051361	0.33977049515417
GO:0000900	mRNA regulatory element binding translation repressor activity	5/2245	18/18639	0.277777777777778	2.30623608017817	0.0564937607408363	0.340327148037791
GO:0031690	adrenergic receptor binding	5/2245	18/18639	0.277777777777778	2.30623608017817	0.0564937607408363	0.340327148037791
GO:0001221	transcription coregulator binding	20/2245	115/18639	0.173913043478261	1.44390432845938	0.0575238999608323	0.344866842553643
GO:0001618	virus receptor activity	15/2245	81/18639	0.185185185185185	1.53749072011878	0.0583960472090782	0.348420434783352
GO:0004622	lysophospholipase activity	6/2245	24/18639	0.25	2.07561247216036	0.060475596802716	0.357407910962023
GO:0005540	hyaluronic acid binding	6/2245	24/18639	0.25	2.07561247216036	0.060475596802716	0.357407910962023
GO:0005338	nucleotide-sugar transmembrane transporter activity	4/2245	13/18639	0.307692307692308	2.55459996573582	0.0614849288211581	0.359690107684795
GO:0140666	annealing activity	4/2245	13/18639	0.307692307692308	2.55459996573582	0.0614849288211581	0.359690107684795
GO:0004620	phospholipase activity	19/2245	109/18639	0.174311926605505	1.44721603563474	0.0617270914551293	0.359690107684795
GO:0003725	double-stranded RNA binding	14/2245	75/18639	0.186666666666667	1.54979064587973	0.0623386216296485	0.359890098019313
GO:0044183	protein folding chaperone	14/2245	75/18639	0.186666666666667	1.54979064587973	0.0623386216296485	0.359890098019313
GO:0140272	exogenous protein binding	15/2245	82/18639	0.182926829268293	1.51874083328807	0.063851404904477	0.36692489362158
GO:0004712	protein serine/threonine/tyrosine kinase activity	9/2245	43/18639	0.209302325581395	1.73772206971565	0.067138802702227	0.384046270503106
GO:0046624	sphingolipid transporter activity	5/2245	19/18639	0.263157894736842	2.18485523385301	0.0693466616167747	0.394728678307835
GO:0030165	PDZ domain binding	15/2245	83/18639	0.180722891566265	1.50044275095929	0.069639381898736	0.394728678307835
GO:0016878	acid-thiol ligase activity	7/2245	31/18639	0.225806451612903	1.87474674904806	0.0714852295451689	0.401459399816574
GO:0017025	TBP-class protein binding	6/2245	25/18639	0.24	1.99258797327394	0.07179265930962	0.401459399816574
GO:0042974	nuclear retinoic acid receptor binding	6/2245	25/18639	0.24	1.99258797327394	0.07179265930962	0.401459399816574
GO:0051117	ATPase binding	15/2245	84/18639	0.178571428571429	1.4825803372574	0.0757650184598128	0.420040078330072
GO:0001046	core promoter sequence-specific DNA binding	9/2245	44/18639	0.204545454545455	1.69822838631302	0.0757891079585133	0.420040078330072
GO:0008474	palmitoyl-(protein) hydrolase activity	4/2245	14/18639	0.285714285714286	2.37212853961184	0.0781547682260654	0.425585135274688
GO:0015926	glucosidase activity	4/2245	14/18639	0.285714285714286	2.37212853961184	0.0781547682260654	0.425585135274688
GO:0098599	palmitoyl hydrolase activity	4/2245	14/18639	0.285714285714286	2.37212853961184	0.0781547682260654	0.425585135274688
GO:0098847	sequence-specific single stranded DNA binding	4/2245	14/18639	0.285714285714286	2.37212853961184	0.0781547682260654	0.425585135274688
GO:0004519	endonuclease activity	21/2245	127/18639	0.165354330708661	1.3728460445785	0.0815054788813248	0.441901444195705
GO:0032182	ubiquitin-like protein binding	20/2245	120/18639	0.166666666666667	1.3837416481069	0.0820896369155872	0.442993151339725
GO:0070717	poly-purine tract binding	7/2245	32/18639	0.21875	1.81616091314031	0.0824173304818092	0.442993151339725
GO:0005326	neurotransmitter transmembrane transporter activity	5/2245	20/18639	0.25	2.07561247216036	0.0836684654499632	0.445874258188479
GO:0030742	GTP-dependent protein binding	5/2245	20/18639	0.25	2.07561247216036	0.0836684654499632	0.445874258188479
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	21/2245	128/18639	0.1640625	1.36212068485523	0.0869429901573601	0.461352803090332
GO:0043130	ubiquitin binding	17/2245	100/18639	0.17	1.41141648106904	0.0891890694904762	0.471265973112813
GO:0019838	growth factor binding	22/2245	136/18639	0.161764705882353	1.34304336433905	0.0915270138822139	0.480165379962335
GO:0031406	carboxylic acid binding	29/2245	187/18639	0.155080213903743	1.28754570465562	0.091700190442386	0.480165379962335
GO:0036002	pre-mRNA binding	11/2245	59/18639	0.186440677966102	1.54791438601789	0.0920284890224523	0.480165379962335
GO:0140311	protein sequestering activity	7/2245	33/18639	0.212121212121212	1.76112573395424	0.0942539054834002	0.488689908091297
GO:0017124	SH3 domain binding	19/2245	115/18639	0.165217391304348	1.37170911203641	0.0944879954643511	0.488689908091297
GO:0030291	protein serine/threonine kinase inhibitor activity	9/2245	46/18639	0.195652173913043	1.6243923695168	0.0950423759073168	0.488689908091297
GO:0004521	RNA endonuclease activity	13/2245	73/18639	0.178082191780822	1.47851847331971	0.0952298698205174	0.488689908091297
GO:0004467	long-chain fatty acid-CoA ligase activity	4/2245	15/18639	0.266666666666667	2.21398663697105	0.0968181536236982	0.490781453531511
GO:0016846	carbon-sulfur lyase activity	4/2245	15/18639	0.266666666666667	2.21398663697105	0.0968181536236982	0.490781453531511
GO:0042809	nuclear vitamin D receptor binding	4/2245	15/18639	0.266666666666667	2.21398663697105	0.0968181536236982	0.490781453531511
GO:0034212	protein N-acetyltransferase activity	10/2245	53/18639	0.188679245283019	1.56649997898895	0.0986343839707259	0.491956097124488
GO:1901505	carbohydrate derivative transmembrane transporter activity	10/2245	53/18639	0.188679245283019	1.56649997898895	0.0986343839707259	0.491956097124488
GO:0019200	carbohydrate kinase activity	5/2245	21/18639	0.238095238095238	1.97677378300986	0.0994169498599607	0.491956097124488
GO:0051010	microtubule plus-end binding	5/2245	21/18639	0.238095238095238	1.97677378300986	0.0994169498599607	0.491956097124488
GO:0072542	protein phosphatase activator activity	5/2245	21/18639	0.238095238095238	1.97677378300986	0.0994169498599607	0.491956097124488
GO:0140312	cargo adaptor activity	5/2245	21/18639	0.238095238095238	1.97677378300986	0.0994169498599607	0.491956097124488
GO:0004177	aminopeptidase activity	8/2245	40/18639	0.2	1.66048997772829	0.101050079893577	0.494154704420745
GO:0015036	disulfide oxidoreductase activity	8/2245	40/18639	0.2	1.66048997772829	0.101050079893577	0.494154704420745
GO:0030331	nuclear estrogen receptor binding	8/2245	40/18639	0.2	1.66048997772829	0.101050079893577	0.494154704420745
GO:0043177	organic acid binding	29/2245	189/18639	0.153439153439153	1.27392088238413	0.10148018986761	0.49431951861293
GO:0061733	protein-lysine-acetyltransferase activity	9/2245	47/18639	0.191489361702128	1.58983082973985	0.10564073829451	0.506083539579948
GO:0003774	cytoskeletal motor activity	24/2245	153/18639	0.156862745098039	1.3023450805712	0.10565651160128	0.506083539579948
GO:0015035	protein-disulfide reductase activity	7/2245	34/18639	0.205882352941176	1.7093279182497	0.106980694069439	0.506083539579948
GO:0050661	NADP binding	10/2245	54/18639	0.185185185185185	1.53749072011878	0.108671659583521	0.506083539579948
GO:0001094	TFIID-class transcription factor complex binding	3/2245	10/18639	0.3	2.49073496659243	0.109577029419877	0.506083539579948
GO:0005337	nucleoside transmembrane transporter activity	3/2245	10/18639	0.3	2.49073496659243	0.109577029419877	0.506083539579948
GO:0005345	purine nucleobase transmembrane transporter activity	3/2245	10/18639	0.3	2.49073496659243	0.109577029419877	0.506083539579948
GO:0008641	ubiquitin-like modifier activating enzyme activity	3/2245	10/18639	0.3	2.49073496659243	0.109577029419877	0.506083539579948
GO:0015658	branched-chain amino acid transmembrane transporter activity	3/2245	10/18639	0.3	2.49073496659243	0.109577029419877	0.506083539579948
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/2245	10/18639	0.3	2.49073496659243	0.109577029419877	0.506083539579948
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	3/2245	10/18639	0.3	2.49073496659243	0.109577029419877	0.506083539579948
GO:0016868	intramolecular phosphotransferase activity	3/2245	10/18639	0.3	2.49073496659243	0.109577029419877	0.506083539579948
GO:0031957	very long-chain fatty acid-CoA ligase activity	3/2245	10/18639	0.3	2.49073496659243	0.109577029419877	0.506083539579948
GO:0051880	G-quadruplex DNA binding	3/2245	10/18639	0.3	2.49073496659243	0.109577029419877	0.506083539579948
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	14/2245	82/18639	0.170731707317073	1.41749144440219	0.111994609334089	0.515340508633241
GO:0046966	nuclear thyroid hormone receptor binding	6/2245	28/18639	0.214285714285714	1.77909640470888	0.112425404705952	0.515420881133538
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	8/2245	41/18639	0.195121951219512	1.61999022217394	0.112996459835554	0.516141338516248
GO:0005324	long-chain fatty acid transmembrane transporter activity	4/2245	16/18639	0.25	2.07561247216036	0.117340211383136	0.526342602858887
GO:0008296	3'-5'-DNA exonuclease activity	4/2245	16/18639	0.25	2.07561247216036	0.117340211383136	0.526342602858887
GO:0017070	U6 snRNA binding	4/2245	16/18639	0.25	2.07561247216036	0.117340211383136	0.526342602858887
GO:0043023	ribosomal large subunit binding	4/2245	16/18639	0.25	2.07561247216036	0.117340211383136	0.526342602858887
GO:0055102	lipase inhibitor activity	4/2245	16/18639	0.25	2.07561247216036	0.117340211383136	0.526342602858887
GO:0010485	histone H4 acetyltransferase activity	7/2245	35/18639	0.2	1.66048997772829	0.120575691302866	0.535137950977326
GO:0061631	ubiquitin conjugating enzyme activity	7/2245	35/18639	0.2	1.66048997772829	0.120575691302866	0.535137950977326
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	14/2245	83/18639	0.168674698795181	1.40041323422867	0.120588423596334	0.535137950977326
GO:0004402	histone acetyltransferase activity	8/2245	42/18639	0.19047619047619	1.58141902640789	0.125669618257804	0.555709269388233
GO:0003785	actin monomer binding	6/2245	29/18639	0.206896551724138	1.71774825282236	0.128097112019116	0.560481048027502
GO:0010484	histone H3 acetyltransferase activity	6/2245	29/18639	0.206896551724138	1.71774825282236	0.128097112019116	0.560481048027502
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	6/2245	29/18639	0.206896551724138	1.71774825282236	0.128097112019116	0.560481048027502
GO:0020037	heme binding	22/2245	142/18639	0.154929577464789	1.2862950531698	0.129022585131635	0.562556516290731
GO:0005096	GTPase activator activity	39/2245	271/18639	0.143911439114391	1.1948175116495	0.136144515455846	0.576257344705412
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/2245	11/18639	0.272727272727273	2.26430451508402	0.137738260386506	0.576257344705412
GO:0004523	RNA-DNA hybrid ribonuclease activity	3/2245	11/18639	0.272727272727273	2.26430451508402	0.137738260386506	0.576257344705412
GO:0015173	aromatic amino acid transmembrane transporter activity	3/2245	11/18639	0.272727272727273	2.26430451508402	0.137738260386506	0.576257344705412
GO:0015205	nucleobase transmembrane transporter activity	3/2245	11/18639	0.272727272727273	2.26430451508402	0.137738260386506	0.576257344705412
GO:0032404	mismatch repair complex binding	3/2245	11/18639	0.272727272727273	2.26430451508402	0.137738260386506	0.576257344705412
GO:0034056	estrogen response element binding	3/2245	11/18639	0.272727272727273	2.26430451508402	0.137738260386506	0.576257344705412
GO:0035252	UDP-xylosyltransferase activity	3/2245	11/18639	0.272727272727273	2.26430451508402	0.137738260386506	0.576257344705412
GO:0042285	xylosyltransferase activity	3/2245	11/18639	0.272727272727273	2.26430451508402	0.137738260386506	0.576257344705412
GO:0047676	arachidonate-CoA ligase activity	3/2245	11/18639	0.272727272727273	2.26430451508402	0.137738260386506	0.576257344705412
GO:0070990	snRNP binding	3/2245	11/18639	0.272727272727273	2.26430451508402	0.137738260386506	0.576257344705412
GO:0016779	nucleotidyltransferase activity	21/2245	136/18639	0.154411764705882	1.28199593868728	0.138878451798065	0.576257344705412
GO:0140789	histone phosphatase activity	21/2245	136/18639	0.154411764705882	1.28199593868728	0.138878451798065	0.576257344705412
GO:0048156	tau protein binding	8/2245	43/18639	0.186046511627907	1.54464183974724	0.139048090384793	0.576257344705412
GO:0004659	prenyltransferase activity	4/2245	17/18639	0.235294117647059	1.95351762085681	0.139558715397782	0.576257344705412
GO:0031489	myosin V binding	4/2245	17/18639	0.235294117647059	1.95351762085681	0.139558715397782	0.576257344705412
GO:0015605	organophosphate ester transmembrane transporter activity	9/2245	50/18639	0.18	1.49444097995546	0.141210087951914	0.581151748105732
GO:0016504	peptidase activator activity	10/2245	57/18639	0.175438596491228	1.456570155902	0.142096489320323	0.582876059810668
GO:0019903	protein phosphatase binding	22/2245	144/18639	0.152777777777778	1.268429844098	0.143298597827814	0.584174942925314
GO:0008187	poly-pyrimidine tract binding	6/2245	30/18639	0.2	1.66048997772829	0.14475545899272	0.584174942925314
GO:0043995	histone H4K5 acetyltransferase activity	6/2245	30/18639	0.2	1.66048997772829	0.14475545899272	0.584174942925314
GO:0043996	histone H4K8 acetyltransferase activity	6/2245	30/18639	0.2	1.66048997772829	0.14475545899272	0.584174942925314
GO:0043997	histone H4K12 acetyltransferase activity	6/2245	30/18639	0.2	1.66048997772829	0.14475545899272	0.584174942925314
GO:0019902	phosphatase binding	28/2245	190/18639	0.147368421052632	1.22351893095768	0.150713449299904	0.605945602943781
GO:0004721	phosphoprotein phosphatase activity	26/2245	175/18639	0.148571428571429	1.23350684059815	0.151180795117919	0.605945602943781
GO:0016790	thiolester hydrolase activity	8/2245	44/18639	0.181818181818182	1.50953634338935	0.153105642035078	0.605945602943781
GO:0030020	extracellular matrix structural constituent conferring tensile strength	8/2245	44/18639	0.181818181818182	1.50953634338935	0.153105642035078	0.605945602943781
GO:0038024	cargo receptor activity	11/2245	65/18639	0.169230769230769	1.4050299811547	0.153548718847512	0.605945602943781
GO:0005048	signal sequence binding	9/2245	51/18639	0.176470588235294	1.4651382156426	0.154270924700173	0.605945602943781
GO:0015295	solute:proton symporter activity	5/2245	24/18639	0.208333333333333	1.72967706013363	0.154523417591116	0.605945602943781
GO:0070300	phosphatidic acid binding	5/2245	24/18639	0.208333333333333	1.72967706013363	0.154523417591116	0.605945602943781
GO:0140033	acetylation-dependent protein binding	5/2245	24/18639	0.208333333333333	1.72967706013363	0.154523417591116	0.605945602943781
GO:0000049	tRNA binding	13/2245	80/18639	0.1625	1.34914810690423	0.161148366985839	0.626226961330992
GO:0030295	protein kinase activator activity	21/2245	139/18639	0.151079136690647	1.25432696159331	0.162184081557147	0.626226961330992
GO:0008327	methyl-CpG binding	6/2245	31/18639	0.193548387096774	1.60692578489834	0.162340314060133	0.626226961330992
GO:0008409	5'-3' exonuclease activity	4/2245	18/18639	0.222222222222222	1.84498886414254	0.163291559585481	0.626226961330992
GO:0035615	clathrin adaptor activity	4/2245	18/18639	0.222222222222222	1.84498886414254	0.163291559585481	0.626226961330992
GO:0005085	guanyl-nucleotide exchange factor activity	33/2245	230/18639	0.143478260869565	1.19122107097899	0.163575994394787	0.626226961330992
GO:0008514	organic anion transmembrane transporter activity	38/2245	269/18639	0.141263940520446	1.17283678724303	0.167349207871631	0.626226961330992
GO:0005080	protein kinase C binding	9/2245	52/18639	0.173076923076923	1.4369624807264	0.167898259824965	0.626226961330992
GO:0008504	monoamine transmembrane transporter activity	3/2245	12/18639	0.25	2.07561247216036	0.168014959959497	0.626226961330992
GO:0010853	cyclase activator activity	3/2245	12/18639	0.25	2.07561247216036	0.168014959959497	0.626226961330992
GO:0016801	hydrolase activity, acting on ether bonds	3/2245	12/18639	0.25	2.07561247216036	0.168014959959497	0.626226961330992
GO:0016803	ether hydrolase activity	3/2245	12/18639	0.25	2.07561247216036	0.168014959959497	0.626226961330992
GO:0070008	serine-type exopeptidase activity	3/2245	12/18639	0.25	2.07561247216036	0.168014959959497	0.626226961330992
GO:0097371	MDM2/MDM4 family protein binding	3/2245	12/18639	0.25	2.07561247216036	0.168014959959497	0.626226961330992
GO:0097677	STAT family protein binding	3/2245	12/18639	0.25	2.07561247216036	0.168014959959497	0.626226961330992
GO:0015101	organic cation transmembrane transporter activity	13/2245	81/18639	0.160493827160494	1.33249195743628	0.17211679755667	0.626226961330992
GO:0033192	calmodulin-dependent protein phosphatase activity	13/2245	81/18639	0.160493827160494	1.33249195743628	0.17211679755667	0.626226961330992
GO:0140791	histone H2AXS140 phosphatase activity	13/2245	81/18639	0.160493827160494	1.33249195743628	0.17211679755667	0.626226961330992
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	13/2245	81/18639	0.160493827160494	1.33249195743628	0.17211679755667	0.626226961330992
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	13/2245	81/18639	0.160493827160494	1.33249195743628	0.17211679755667	0.626226961330992
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	13/2245	81/18639	0.160493827160494	1.33249195743628	0.17211679755667	0.626226961330992
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	13/2245	81/18639	0.160493827160494	1.33249195743628	0.17211679755667	0.626226961330992
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	13/2245	81/18639	0.160493827160494	1.33249195743628	0.17211679755667	0.626226961330992
GO:1990439	MAP kinase serine/threonine phosphatase activity	13/2245	81/18639	0.160493827160494	1.33249195743628	0.17211679755667	0.626226961330992
GO:0004722	protein serine/threonine phosphatase activity	16/2245	103/18639	0.155339805825243	1.28970095357537	0.17225007837733	0.626226961330992
GO:0008139	nuclear localization sequence binding	5/2245	25/18639	0.2	1.66048997772829	0.17520610716149	0.629631168963627
GO:0015645	fatty acid ligase activity	5/2245	25/18639	0.2	1.66048997772829	0.17520610716149	0.629631168963627
GO:0019211	phosphatase activator activity	5/2245	25/18639	0.2	1.66048997772829	0.17520610716149	0.629631168963627
GO:0120515	fatty acid-CoA ligase activity	5/2245	25/18639	0.2	1.66048997772829	0.17520610716149	0.629631168963627
GO:0001098	basal transcription machinery binding	10/2245	60/18639	0.166666666666667	1.3837416481069	0.180202283342411	0.643874634177611
GO:0001099	basal RNA polymerase II transcription machinery binding	10/2245	60/18639	0.166666666666667	1.3837416481069	0.180202283342411	0.643874634177611
GO:0043425	bHLH transcription factor binding	6/2245	32/18639	0.1875	1.55670935412027	0.180784079501284	0.644107848966004
GO:0016776	phosphotransferase activity, phosphate group as acceptor	7/2245	39/18639	0.179487179487179	1.4901833133459	0.182956846848978	0.649871805230764
GO:0033549	MAP kinase phosphatase activity	13/2245	82/18639	0.158536585365854	1.31624205551632	0.183444166352228	0.649871805230764
GO:0005229	intracellularly calcium-gated chloride channel activity	4/2245	19/18639	0.210526315789474	1.74788418708241	0.188343532377136	0.657883431020418
GO:0015245	fatty acid transmembrane transporter activity	4/2245	19/18639	0.210526315789474	1.74788418708241	0.188343532377136	0.657883431020418
GO:0050145	nucleoside monophosphate kinase activity	4/2245	19/18639	0.210526315789474	1.74788418708241	0.188343532377136	0.657883431020418
GO:0097001	ceramide binding	4/2245	19/18639	0.210526315789474	1.74788418708241	0.188343532377136	0.657883431020418
GO:0141147	intracellularly calcium-gated channel activity	4/2245	19/18639	0.210526315789474	1.74788418708241	0.188343532377136	0.657883431020418
GO:0019210	kinase inhibitor activity	14/2245	90/18639	0.155555555555556	1.29149220489978	0.190777636996827	0.664309083207635
GO:0019842	vitamin binding	22/2245	150/18639	0.146666666666667	1.21769265033408	0.191248565253842	0.664309083207635
GO:0005227	calcium-activated cation channel activity	5/2245	26/18639	0.192307692307692	1.59662497858489	0.196865326734143	0.667948579925134
GO:0008143	poly(A) binding	5/2245	26/18639	0.192307692307692	1.59662497858489	0.196865326734143	0.667948579925134
GO:0070006	metalloaminopeptidase activity	5/2245	26/18639	0.192307692307692	1.59662497858489	0.196865326734143	0.667948579925134
GO:0120014	phospholipid transfer activity	5/2245	26/18639	0.192307692307692	1.59662497858489	0.196865326734143	0.667948579925134
GO:0031490	chromatin DNA binding	19/2245	128/18639	0.1484375	1.23239490534521	0.197443613701699	0.667948579925134
GO:0001784	phosphotyrosine residue binding	8/2245	47/18639	0.170212765957447	1.41318295976875	0.199027030772211	0.667948579925134
GO:0002161	aminoacyl-tRNA editing activity	3/2245	13/18639	0.230769230769231	1.91594997430187	0.199973969300999	0.667948579925134
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/2245	13/18639	0.230769230769231	1.91594997430187	0.199973969300999	0.667948579925134
GO:0019855	calcium channel inhibitor activity	3/2245	13/18639	0.230769230769231	1.91594997430187	0.199973969300999	0.667948579925134
GO:0045159	myosin II binding	3/2245	13/18639	0.230769230769231	1.91594997430187	0.199973969300999	0.667948579925134
GO:0071837	HMG box domain binding	3/2245	13/18639	0.230769230769231	1.91594997430187	0.199973969300999	0.667948579925134
GO:0097157	pre-mRNA intronic binding	3/2245	13/18639	0.230769230769231	1.91594997430187	0.199973969300999	0.667948579925134
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	6/2245	33/18639	0.181818181818182	1.50953634338935	0.200013007060814	0.667948579925134
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	7/2245	40/18639	0.175	1.45292873051225	0.200331009536488	0.667948579925134
GO:0050997	quaternary ammonium group binding	7/2245	40/18639	0.175	1.45292873051225	0.200331009536488	0.667948579925134
GO:0004860	protein kinase inhibitor activity	13/2245	84/18639	0.154761904761905	1.28490295895641	0.207122101415097	0.686918245916558
GO:0017018	myosin phosphatase activity	13/2245	84/18639	0.154761904761905	1.28490295895641	0.207122101415097	0.686918245916558
GO:0046906	tetrapyrrole binding	22/2245	152/18639	0.144736842105263	1.20167037861915	0.208841195988954	0.690782417501924
GO:0051020	GTPase binding	43/2245	315/18639	0.136507936507936	1.13335030225899	0.210693615205919	0.692580827949734
GO:0140313	molecular sequestering activity	9/2245	55/18639	0.163636363636364	1.35858270905042	0.211903217626578	0.692580827949734
GO:0003724	RNA helicase activity	12/2245	77/18639	0.155844155844156	1.29388829433373	0.212190651466812	0.692580827949734
GO:0019888	protein phosphatase regulator activity	16/2245	107/18639	0.149532710280374	1.24148783381554	0.213789502499053	0.692580827949734
GO:0010851	cyclase regulator activity	4/2245	20/18639	0.2	1.66048997772829	0.214512299108929	0.692580827949734
GO:0015095	magnesium ion transmembrane transporter activity	4/2245	20/18639	0.2	1.66048997772829	0.214512299108929	0.692580827949734
GO:0043024	ribosomal small subunit binding	4/2245	20/18639	0.2	1.66048997772829	0.214512299108929	0.692580827949734
GO:0061608	nuclear import signal receptor activity	4/2245	20/18639	0.2	1.66048997772829	0.214512299108929	0.692580827949734
GO:0140693	molecular condensate scaffold activity	8/2245	48/18639	0.166666666666667	1.3837416481069	0.215457030917141	0.692580827949734
GO:0016298	lipase activity	19/2245	130/18639	0.146153846153846	1.21343498372452	0.216905116562771	0.692580827949734
GO:0004812	aminoacyl-tRNA ligase activity	7/2245	41/18639	0.170731707317073	1.41749144440219	0.218311652121974	0.692580827949734
GO:0016875	ligase activity, forming carbon-oxygen bonds	7/2245	41/18639	0.170731707317073	1.41749144440219	0.218311652121974	0.692580827949734
GO:0004364	glutathione transferase activity	5/2245	27/18639	0.185185185185185	1.53749072011878	0.21938205857269	0.692580827949734
GO:0004683	calcium/calmodulin-dependent protein kinase activity	5/2245	27/18639	0.185185185185185	1.53749072011878	0.21938205857269	0.692580827949734
GO:0008266	poly(U) RNA binding	5/2245	27/18639	0.185185185185185	1.53749072011878	0.21938205857269	0.692580827949734
GO:0016405	CoA-ligase activity	5/2245	27/18639	0.185185185185185	1.53749072011878	0.21938205857269	0.692580827949734
GO:0023026	MHC class II protein complex binding	5/2245	27/18639	0.185185185185185	1.53749072011878	0.21938205857269	0.692580827949734
GO:0035255	ionotropic glutamate receptor binding	5/2245	27/18639	0.185185185185185	1.53749072011878	0.21938205857269	0.692580827949734
GO:0140101	catalytic activity, acting on a tRNA	20/2245	139/18639	0.143884892086331	1.19459710627934	0.230490083895044	0.718017635942342
GO:0001222	transcription corepressor binding	8/2245	49/18639	0.163265306122449	1.35550202263533	0.232377647729853	0.718017635942342
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/2245	14/18639	0.214285714285714	1.77909640470888	0.233197387775981	0.718017635942342
GO:0032036	myosin heavy chain binding	3/2245	14/18639	0.214285714285714	1.77909640470888	0.233197387775981	0.718017635942342
GO:0034236	protein kinase A catalytic subunit binding	3/2245	14/18639	0.214285714285714	1.77909640470888	0.233197387775981	0.718017635942342
GO:0044548	S100 protein binding	3/2245	14/18639	0.214285714285714	1.77909640470888	0.233197387775981	0.718017635942342
GO:0061665	SUMO ligase activity	3/2245	14/18639	0.214285714285714	1.77909640470888	0.233197387775981	0.718017635942342
GO:0070742	C2H2 zinc finger domain binding	3/2245	14/18639	0.214285714285714	1.77909640470888	0.233197387775981	0.718017635942342
GO:0071933	Arp2/3 complex binding	3/2245	14/18639	0.214285714285714	1.77909640470888	0.233197387775981	0.718017635942342
GO:1990825	sequence-specific mRNA binding	3/2245	14/18639	0.214285714285714	1.77909640470888	0.233197387775981	0.718017635942342
GO:0051015	actin filament binding	29/2245	209/18639	0.138755980861244	1.15201457784977	0.23448731681424	0.720211044500879
GO:0043175	RNA polymerase core enzyme binding	7/2245	42/18639	0.166666666666667	1.3837416481069	0.236840058894808	0.72535366260979
GO:0004536	DNA nuclease activity	10/2245	64/18639	0.15625	1.29725779510022	0.237325015513067	0.72535366260979
GO:0016410	N-acyltransferase activity	14/2245	94/18639	0.148936170212766	1.23653508979766	0.23795312129926	0.725495213350067
GO:0008186	ATP-dependent activity, acting on RNA	12/2245	79/18639	0.151898734177215	1.26113162865439	0.238635441557916	0.725573095483521
GO:0019208	phosphatase regulator activity	17/2245	117/18639	0.145299145299145	1.20633887270858	0.240393551982561	0.725573095483521
GO:0005154	epidermal growth factor receptor binding	6/2245	35/18639	0.171428571428571	1.4232771237671	0.2405083947154	0.725573095483521
GO:0009931	calcium-dependent protein serine/threonine kinase activity	4/2245	21/18639	0.19047619047619	1.58141902640789	0.241593557755746	0.725573095483521
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	4/2245	21/18639	0.19047619047619	1.58141902640789	0.241593557755746	0.725573095483521
GO:0016866	intramolecular transferase activity	5/2245	28/18639	0.178571428571429	1.4825803372574	0.24263350506546	0.725573095483521
GO:0036408	histone H3K14 acetyltransferase activity	5/2245	28/18639	0.178571428571429	1.4825803372574	0.24263350506546	0.725573095483521
GO:0046625	sphingolipid binding	5/2245	28/18639	0.178571428571429	1.4825803372574	0.24263350506546	0.725573095483521
GO:0019209	kinase activator activity	21/2245	148/18639	0.141891891891892	1.17805032203696	0.243491117140645	0.726395748981781
GO:0008234	cysteine-type peptidase activity	26/2245	187/18639	0.13903743315508	1.15435132141539	0.245882825727154	0.73178015198511
GO:0106310	protein serine kinase activity	48/2245	361/18639	0.132963988919668	1.10392685499941	0.252215364322904	0.748839426930147
GO:0008200	ion channel inhibitor activity	7/2245	43/18639	0.162790697674419	1.35156160977884	0.255855163882867	0.757841779957091
GO:0003714	transcription corepressor activity	28/2245	204/18639	0.137254901960784	1.1395519454998	0.258007225051471	0.762405236111812
GO:0016407	acetyltransferase activity	14/2245	96/18639	0.145833333333333	1.21077394209354	0.263130689341833	0.77039004721748
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	5/2245	29/18639	0.172413793103448	1.43145687735197	0.266495253616781	0.77039004721748
GO:0035250	UDP-galactosyltransferase activity	5/2245	29/18639	0.172413793103448	1.43145687735197	0.266495253616781	0.77039004721748
GO:0043236	laminin binding	5/2245	29/18639	0.172413793103448	1.43145687735197	0.266495253616781	0.77039004721748
GO:0097472	cyclin-dependent protein kinase activity	5/2245	29/18639	0.172413793103448	1.43145687735197	0.266495253616781	0.77039004721748
GO:0003779	actin binding	58/2245	443/18639	0.130925507900677	1.0870024684903	0.266623773602457	0.77039004721748
GO:0000774	adenyl-nucleotide exchange factor activity	3/2245	15/18639	0.2	1.66048997772829	0.267292196314052	0.77039004721748
GO:0004559	alpha-mannosidase activity	3/2245	15/18639	0.2	1.66048997772829	0.267292196314052	0.77039004721748
GO:0010181	FMN binding	3/2245	15/18639	0.2	1.66048997772829	0.267292196314052	0.77039004721748
GO:0140776	protein-containing complex destabilizing activity	3/2245	15/18639	0.2	1.66048997772829	0.267292196314052	0.77039004721748
GO:0005010	insulin-like growth factor receptor activity	8/2245	51/18639	0.156862745098039	1.3023450805712	0.267505124655308	0.77039004721748
GO:0046972	histone H4K16 acetyltransferase activity	4/2245	22/18639	0.181818181818182	1.50953634338935	0.269385375799327	0.772238077291404
GO:0061133	endopeptidase activator activity	4/2245	22/18639	0.181818181818182	1.50953634338935	0.269385375799327	0.772238077291404
GO:0035064	methylated histone binding	11/2245	74/18639	0.148648648648649	1.23414795641967	0.274843570652534	0.781986208372895
GO:0048029	monosaccharide binding	11/2245	74/18639	0.148648648648649	1.23414795641967	0.274843570652534	0.781986208372895
GO:0001223	transcription coactivator binding	7/2245	44/18639	0.159090909090909	1.32084430046568	0.275294262610827	0.781986208372895
GO:0016248	channel inhibitor activity	7/2245	44/18639	0.159090909090909	1.32084430046568	0.275294262610827	0.781986208372895
GO:0002020	protease binding	19/2245	136/18639	0.139705882352941	1.15990108738373	0.279995752796356	0.793533417584219
GO:0022829	wide pore channel activity	6/2245	37/18639	0.162162162162162	1.3463432251851	0.283161980901324	0.800687052571318
GO:0022839	monoatomic ion-gated channel activity	5/2245	30/18639	0.166666666666667	1.3837416481069	0.290843212541593	0.820546348505355
GO:0008009	chemokine activity	7/2245	45/18639	0.155555555555556	1.29149220489978	0.29509369209428	0.823660679624349
GO:0141110	transporter inhibitor activity	7/2245	45/18639	0.155555555555556	1.29149220489978	0.29509369209428	0.823660679624349
GO:0003887	DNA-directed DNA polymerase activity	4/2245	23/18639	0.173913043478261	1.44390432845938	0.29769174510581	0.823660679624349
GO:0017134	fibroblast growth factor binding	4/2245	23/18639	0.173913043478261	1.44390432845938	0.29769174510581	0.823660679624349
GO:0070577	lysine-acetylated histone binding	4/2245	23/18639	0.173913043478261	1.44390432845938	0.29769174510581	0.823660679624349
GO:0072341	modified amino acid binding	13/2245	91/18639	0.142857142857143	1.18606426980592	0.299018141986568	0.823660679624349
GO:0004708	MAP kinase kinase activity	3/2245	16/18639	0.1875	1.55670935412027	0.301896500528878	0.823660679624349
GO:0005159	insulin-like growth factor receptor binding	3/2245	16/18639	0.1875	1.55670935412027	0.301896500528878	0.823660679624349
GO:0005521	lamin binding	3/2245	16/18639	0.1875	1.55670935412027	0.301896500528878	0.823660679624349
GO:0008142	oxysterol binding	3/2245	16/18639	0.1875	1.55670935412027	0.301896500528878	0.823660679624349
GO:0015562	efflux transmembrane transporter activity	3/2245	16/18639	0.1875	1.55670935412027	0.301896500528878	0.823660679624349
GO:0015923	mannosidase activity	3/2245	16/18639	0.1875	1.55670935412027	0.301896500528878	0.823660679624349
GO:0030275	LRR domain binding	3/2245	16/18639	0.1875	1.55670935412027	0.301896500528878	0.823660679624349
GO:0097027	ubiquitin-protein transferase activator activity	3/2245	16/18639	0.1875	1.55670935412027	0.301896500528878	0.823660679624349
GO:0004674	protein serine/threonine kinase activity	56/2245	433/18639	0.12933025404157	1.0737579532654	0.303835101438581	0.823660679624349
GO:0051018	protein kinase A binding	8/2245	53/18639	0.150943396226415	1.25319998319116	0.30402428023452	0.823660679624349
GO:0140296	general transcription initiation factor binding	8/2245	53/18639	0.150943396226415	1.25319998319116	0.30402428023452	0.823660679624349
GO:0042887	amide transmembrane transporter activity	6/2245	38/18639	0.157894736842105	1.3109131403118	0.305083953244843	0.823660679624349
GO:0140034	methylation-dependent protein binding	11/2245	76/18639	0.144736842105263	1.20167037861915	0.305236797163601	0.823660679624349
GO:0061134	peptidase regulator activity	30/2245	226/18639	0.132743362831858	1.10209511796125	0.312674521690029	0.823660679624349
GO:0052689	carboxylic ester hydrolase activity	13/2245	92/18639	0.141304347826087	1.17317226687324	0.313042174882551	0.823660679624349
GO:0005164	tumor necrosis factor receptor binding	5/2245	31/18639	0.161290322580645	1.33910482074862	0.315555308403413	0.823660679624349
GO:0005310	dicarboxylic acid transmembrane transporter activity	5/2245	31/18639	0.161290322580645	1.33910482074862	0.315555308403413	0.823660679624349
GO:0072349	modified amino acid transmembrane transporter activity	5/2245	31/18639	0.161290322580645	1.33910482074862	0.315555308403413	0.823660679624349
GO:0008080	N-acetyltransferase activity	10/2245	69/18639	0.144927536231884	1.20325360704948	0.316368055237441	0.823660679624349
GO:0042578	phosphoric ester hydrolase activity	47/2245	363/18639	0.129476584022039	1.07497285059545	0.319883011070781	0.823660679624349
GO:0031267	small GTPase binding	37/2245	283/18639	0.130742049469965	1.08547931406266	0.321975016152183	0.823660679624349
GO:0140463	chromatin-protein adaptor activity	8/2245	54/18639	0.148148148148148	1.22999257609503	0.322681596268788	0.823660679624349
GO:0001091	RNA polymerase II general transcription initiation factor binding	4/2245	24/18639	0.166666666666667	1.3837416481069	0.326325410608748	0.823660679624349
GO:0005315	phosphate transmembrane transporter activity	4/2245	24/18639	0.166666666666667	1.3837416481069	0.326325410608748	0.823660679624349
GO:0042625	ATPase-coupled ion transmembrane transporter activity	4/2245	24/18639	0.166666666666667	1.3837416481069	0.326325410608748	0.823660679624349
GO:0043998	histone H2A acetyltransferase activity	4/2245	24/18639	0.166666666666667	1.3837416481069	0.326325410608748	0.823660679624349
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	4/2245	24/18639	0.166666666666667	1.3837416481069	0.326325410608748	0.823660679624349
GO:0046961	proton-transporting ATPase activity, rotational mechanism	4/2245	24/18639	0.166666666666667	1.3837416481069	0.326325410608748	0.823660679624349
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	6/2245	39/18639	0.153846153846154	1.27729998286791	0.327288881680455	0.823660679624349
GO:0046943	carboxylic acid transmembrane transporter activity	25/2245	188/18639	0.132978723404255	1.10404918731934	0.329654283969135	0.823660679624349
GO:0008028	monocarboxylic acid transmembrane transporter activity	10/2245	70/18639	0.142857142857143	1.18606426980592	0.332877124798445	0.823660679624349
GO:0004550	nucleoside diphosphate kinase activity	3/2245	17/18639	0.176470588235294	1.4651382156426	0.336683168771255	0.823660679624349
GO:0005092	GDP-dissociation inhibitor activity	3/2245	17/18639	0.176470588235294	1.4651382156426	0.336683168771255	0.823660679624349
GO:0008429	phosphatidylethanolamine binding	3/2245	17/18639	0.176470588235294	1.4651382156426	0.336683168771255	0.823660679624349
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	3/2245	17/18639	0.176470588235294	1.4651382156426	0.336683168771255	0.823660679624349
GO:0017110	nucleoside diphosphate phosphatase activity	3/2245	17/18639	0.176470588235294	1.4651382156426	0.336683168771255	0.823660679624349
GO:0030169	low-density lipoprotein particle binding	3/2245	17/18639	0.176470588235294	1.4651382156426	0.336683168771255	0.823660679624349
GO:0032977	membrane insertase activity	3/2245	17/18639	0.176470588235294	1.4651382156426	0.336683168771255	0.823660679624349
GO:0036041	long-chain fatty acid binding	3/2245	17/18639	0.176470588235294	1.4651382156426	0.336683168771255	0.823660679624349
GO:0046965	nuclear retinoid X receptor binding	3/2245	17/18639	0.176470588235294	1.4651382156426	0.336683168771255	0.823660679624349
GO:0048038	quinone binding	3/2245	17/18639	0.176470588235294	1.4651382156426	0.336683168771255	0.823660679624349
GO:0051787	misfolded protein binding	3/2245	17/18639	0.176470588235294	1.4651382156426	0.336683168771255	0.823660679624349
GO:0140030	modification-dependent protein binding	23/2245	173/18639	0.132947976878613	1.10379391583094	0.339170851651716	0.823660679624349
GO:0005342	organic acid transmembrane transporter activity	25/2245	189/18639	0.132275132275132	1.0982076572277	0.33969698732463	0.823660679624349
GO:0008378	galactosyltransferase activity	5/2245	32/18639	0.15625	1.29725779510022	0.340512943385289	0.823660679624349
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	5/2245	32/18639	0.15625	1.29725779510022	0.340512943385289	0.823660679624349
GO:0042910	xenobiotic transmembrane transporter activity	5/2245	32/18639	0.15625	1.29725779510022	0.340512943385289	0.823660679624349
GO:0071813	lipoprotein particle binding	5/2245	32/18639	0.15625	1.29725779510022	0.340512943385289	0.823660679624349
GO:0071814	protein-lipid complex binding	5/2245	32/18639	0.15625	1.29725779510022	0.340512943385289	0.823660679624349
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0004862	cAMP-dependent protein kinase inhibitor activity	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0008239	dipeptidyl-peptidase activity	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0015187	glycine transmembrane transporter activity	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0016303	1-phosphatidylinositol-3-kinase activity	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0016783	sulfurtransferase activity	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0019911	structural constituent of myelin sheath	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0035374	chondroitin sulfate binding	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0042975	peroxisome proliferator activated receptor binding	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0043121	neurotrophin binding	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0047429	nucleoside triphosphate diphosphatase activity	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0140135	mechanosensitive monoatomic cation channel activity	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0140999	histone H3K4 trimethyltransferase activity	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/2245	10/18639	0.2	1.66048997772829	0.343467163917131	0.823660679624349
GO:1901682	sulfur compound transmembrane transporter activity	9/2245	63/18639	0.142857142857143	1.18606426980592	0.346067238690803	0.828302968613111
GO:0061791	GTPase motor activity	6/2245	40/18639	0.15	1.24536748329621	0.349693212058801	0.833780947298902
GO:1990606	membrane scission GTPase motor activity	6/2245	40/18639	0.15	1.24536748329621	0.349693212058801	0.833780947298902
GO:0033293	monocarboxylic acid binding	11/2245	79/18639	0.139240506329114	1.15603732626653	0.35224016829901	0.838250934864246
GO:0008081	phosphoric diester hydrolase activity	12/2245	87/18639	0.137931034482759	1.14516550188158	0.354350785644032	0.840818317118932
GO:0047617	fatty acyl-CoA hydrolase activity	4/2245	25/18639	0.16	1.32839198218263	0.355110039836797	0.840818317118932
GO:0004867	serine-type endopeptidase inhibitor activity	13/2245	95/18639	0.136842105263158	1.13612472160356	0.356005372972672	0.840818317118932
GO:0016879	ligase activity, forming carbon-nitrogen bonds	7/2245	48/18639	0.145833333333333	1.21077394209354	0.356016095780911	0.840818317118932
GO:0016741	transferase activity, transferring one-carbon groups	28/2245	215/18639	0.130232558139535	1.08124928782307	0.359061426771153	0.845493586149311
GO:0019783	ubiquitin-like protein peptidase activity	17/2245	127/18639	0.133858267716535	1.11135155989688	0.35964095379393	0.845493586149311
GO:0015297	antiporter activity	18/2245	135/18639	0.133333333333333	1.10699331848552	0.36004938511043	0.845493586149311
GO:0004197	cysteine-type endopeptidase activity	12/2245	88/18639	0.136363636363636	1.13215225754201	0.369543283097407	0.845493586149311
GO:0003746	translation elongation factor activity	3/2245	18/18639	0.166666666666667	1.3837416481069	0.37136149060841	0.845493586149311
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/2245	18/18639	0.166666666666667	1.3837416481069	0.37136149060841	0.845493586149311
GO:0070064	proline-rich region binding	3/2245	18/18639	0.166666666666667	1.3837416481069	0.37136149060841	0.845493586149311
GO:1901611	phosphatidylglycerol binding	3/2245	18/18639	0.166666666666667	1.3837416481069	0.37136149060841	0.845493586149311
GO:0005200	structural constituent of cytoskeleton	15/2245	112/18639	0.133928571428571	1.11193525294305	0.371768259948153	0.845493586149311
GO:0015175	neutral L-amino acid transmembrane transporter activity	6/2245	41/18639	0.146341463414634	1.21499266663045	0.372215765190829	0.845493586149311
GO:0017080	sodium channel regulator activity	6/2245	41/18639	0.146341463414634	1.21499266663045	0.372215765190829	0.845493586149311
GO:0005004	GPI-linked ephrin receptor activity	7/2245	49/18639	0.142857142857143	1.18606426980592	0.37662250378942	0.845493586149311
GO:0005008	hepatocyte growth factor receptor activity	7/2245	49/18639	0.142857142857143	1.18606426980592	0.37662250378942	0.845493586149311
GO:0005009	insulin receptor activity	7/2245	49/18639	0.142857142857143	1.18606426980592	0.37662250378942	0.845493586149311
GO:0005011	macrophage colony-stimulating factor receptor activity	7/2245	49/18639	0.142857142857143	1.18606426980592	0.37662250378942	0.845493586149311
GO:0005018	platelet-derived growth factor alpha-receptor activity	7/2245	49/18639	0.142857142857143	1.18606426980592	0.37662250378942	0.845493586149311
GO:0005020	stem cell factor receptor activity	7/2245	49/18639	0.142857142857143	1.18606426980592	0.37662250378942	0.845493586149311
GO:0008288	boss receptor activity	7/2245	49/18639	0.142857142857143	1.18606426980592	0.37662250378942	0.845493586149311
GO:0036332	placental growth factor receptor activity	7/2245	49/18639	0.142857142857143	1.18606426980592	0.37662250378942	0.845493586149311
GO:0038062	protein tyrosine kinase collagen receptor activity	7/2245	49/18639	0.142857142857143	1.18606426980592	0.37662250378942	0.845493586149311
GO:0060175	brain-derived neurotrophic factor receptor activity	7/2245	49/18639	0.142857142857143	1.18606426980592	0.37662250378942	0.845493586149311
GO:0016289	acyl-CoA hydrolase activity	4/2245	26/18639	0.153846153846154	1.27729998286791	0.383881805855461	0.845493586149311
GO:0034237	protein kinase A regulatory subunit binding	4/2245	26/18639	0.153846153846154	1.27729998286791	0.383881805855461	0.845493586149311
GO:0097602	cullin family protein binding	4/2245	26/18639	0.153846153846154	1.27729998286791	0.383881805855461	0.845493586149311
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	12/2245	89/18639	0.134831460674157	1.11943144565952	0.384816155468965	0.845493586149311
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	12/2245	89/18639	0.134831460674157	1.11943144565952	0.384816155468965	0.845493586149311
GO:0035591	signaling adaptor activity	17/2245	129/18639	0.131782945736434	1.0941213031543	0.384889294325247	0.845493586149311
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0002162	dystroglycan binding	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0008046	axon guidance receptor activity	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0008271	secondary active sulfate transmembrane transporter activity	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0008526	phosphatidylinositol transfer activity	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0015217	ADP transmembrane transporter activity	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0019107	myristoyltransferase activity	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0019215	intermediate filament binding	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0032050	clathrin heavy chain binding	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0032794	GTPase activating protein binding	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0034713	type I transforming growth factor beta receptor binding	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0043522	leucine zipper domain binding	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0140537	transcription regulator activator activity	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/2245	11/18639	0.181818181818182	1.50953634338935	0.389184698035048	0.845493586149311
GO:0008376	acetylgalactosaminyltransferase activity	5/2245	34/18639	0.147058823529412	1.2209485130355	0.390714927216379	0.845870684442403
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	5/2245	34/18639	0.147058823529412	1.2209485130355	0.390714927216379	0.845870684442403
GO:0004520	DNA endonuclease activity	6/2245	42/18639	0.142857142857143	1.18606426980592	0.394778382906832	0.851211034984109
GO:0005006	epidermal growth factor receptor activity	7/2245	50/18639	0.14	1.1623429844098	0.397277323464917	0.851211034984109
GO:0005007	fibroblast growth factor receptor activity	7/2245	50/18639	0.14	1.1623429844098	0.397277323464917	0.851211034984109
GO:0005017	platelet-derived growth factor receptor activity	7/2245	50/18639	0.14	1.1623429844098	0.397277323464917	0.851211034984109
GO:0005019	platelet-derived growth factor beta-receptor activity	7/2245	50/18639	0.14	1.1623429844098	0.397277323464917	0.851211034984109
GO:0032813	tumor necrosis factor receptor superfamily binding	7/2245	50/18639	0.14	1.1623429844098	0.397277323464917	0.851211034984109
GO:0004725	protein tyrosine phosphatase activity	13/2245	98/18639	0.13265306122449	1.10134539339121	0.399854938274921	0.854419437901059
GO:0140793	histone H2AXY142 phosphatase activity	12/2245	90/18639	0.133333333333333	1.10699331848552	0.400145109650536	0.854419437901059
GO:0003756	protein disulfide isomerase activity	3/2245	19/18639	0.157894736842105	1.3109131403118	0.405677357776774	0.855972360655901
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	3/2245	19/18639	0.157894736842105	1.3109131403118	0.405677357776774	0.855972360655901
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/2245	19/18639	0.157894736842105	1.3109131403118	0.405677357776774	0.855972360655901
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/2245	19/18639	0.157894736842105	1.3109131403118	0.405677357776774	0.855972360655901
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	3/2245	19/18639	0.157894736842105	1.3109131403118	0.405677357776774	0.855972360655901
GO:0031420	alkali metal ion binding	3/2245	19/18639	0.157894736842105	1.3109131403118	0.405677357776774	0.855972360655901
GO:0042800	histone H3K4 methyltransferase activity	3/2245	19/18639	0.157894736842105	1.3109131403118	0.405677357776774	0.855972360655901
GO:0008320	protein transmembrane transporter activity	4/2245	27/18639	0.148148148148148	1.22999257609503	0.412490457556813	0.857370012156412
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	4/2245	27/18639	0.148148148148148	1.22999257609503	0.412490457556813	0.857370012156412
GO:0101005	deubiquitinase activity	15/2245	115/18639	0.130434782608696	1.08292824634453	0.412525421765803	0.857370012156412
GO:0016229	steroid dehydrogenase activity	5/2245	35/18639	0.142857142857143	1.18606426980592	0.415749349299875	0.857370012156412
GO:0034061	DNA polymerase activity	5/2245	35/18639	0.142857142857143	1.18606426980592	0.415749349299875	0.857370012156412
GO:0019003	GDP binding	10/2245	75/18639	0.133333333333333	1.10699331848552	0.417089921078968	0.857370012156412
GO:0008173	RNA methyltransferase activity	9/2245	67/18639	0.134328358208955	1.11525446265333	0.417652700706418	0.857370012156412
GO:0005021	vascular endothelial growth factor receptor activity	7/2245	51/18639	0.137254901960784	1.1395519454998	0.417922900548264	0.857370012156412
GO:0005030	neurotrophin receptor activity	7/2245	51/18639	0.137254901960784	1.1395519454998	0.417922900548264	0.857370012156412
GO:0016597	amino acid binding	7/2245	51/18639	0.137254901960784	1.1395519454998	0.417922900548264	0.857370012156412
GO:0004879	nuclear receptor activity	8/2245	59/18639	0.135593220338983	1.12575591710392	0.417970510280613	0.857370012156412
GO:0035173	histone kinase activity	45/2245	360/18639	0.125	1.03780623608018	0.418614500121457	0.857370012156412
GO:0035402	histone H3T11 kinase activity	31/2245	247/18639	0.125506072874494	1.04200788076066	0.432020767886993	0.857370012156412
GO:0000995	RNA polymerase III general transcription initiation factor activity	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0004032	aldose reductase (NADPH) activity	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0004126	cytidine deaminase activity	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0004300	enoyl-CoA hydratase activity	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0005095	GTPase inhibitor activity	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0008179	adenylate cyclase binding	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0008603	cAMP-dependent protein kinase regulator activity	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0015132	prostaglandin transmembrane transporter activity	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0016208	AMP binding	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0016840	carbon-nitrogen lyase activity	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0031543	peptidyl-proline dioxygenase activity	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0042301	phosphate ion binding	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0045295	gamma-catenin binding	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0070679	inositol 1,4,5 trisphosphate binding	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:1990817	poly(A) RNA polymerase activity	2/2245	12/18639	0.166666666666667	1.3837416481069	0.433418645650157	0.857370012156412
GO:0005548	phospholipid transporter activity	9/2245	68/18639	0.132352941176471	1.09885366173195	0.435592377298511	0.857370012156412
GO:0140223	general transcription initiation factor activity	9/2245	68/18639	0.132352941176471	1.09885366173195	0.435592377298511	0.857370012156412
GO:1990841	promoter-specific chromatin binding	9/2245	68/18639	0.132352941176471	1.09885366173195	0.435592377298511	0.857370012156412
GO:0004714	transmembrane receptor protein tyrosine kinase activity	8/2245	60/18639	0.133333333333333	1.10699331848552	0.437096953411406	0.857370012156412
GO:0098531	ligand-modulated transcription factor activity	8/2245	60/18639	0.133333333333333	1.10699331848552	0.437096953411406	0.857370012156412
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	3/2245	20/18639	0.15	1.24536748329621	0.439412368129923	0.857370012156412
GO:0016004	phospholipase activator activity	3/2245	20/18639	0.15	1.24536748329621	0.439412368129923	0.857370012156412
GO:0016505	peptidase activator activity involved in apoptotic process	3/2245	20/18639	0.15	1.24536748329621	0.439412368129923	0.857370012156412
GO:0140664	ATP-dependent DNA damage sensor activity	3/2245	20/18639	0.15	1.24536748329621	0.439412368129923	0.857370012156412
GO:1990782	protein tyrosine kinase binding	15/2245	117/18639	0.128205128205128	1.06441665238993	0.43983001524053	0.857370012156412
GO:0000993	RNA polymerase II complex binding	5/2245	36/18639	0.138888888888889	1.15311804008909	0.440610834003307	0.857370012156412
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	5/2245	36/18639	0.138888888888889	1.15311804008909	0.440610834003307	0.857370012156412
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	5/2245	36/18639	0.138888888888889	1.15311804008909	0.440610834003307	0.857370012156412
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	5/2245	36/18639	0.138888888888889	1.15311804008909	0.440610834003307	0.857370012156412
GO:0019789	SUMO transferase activity	4/2245	28/18639	0.142857142857143	1.18606426980592	0.440799949638705	0.857370012156412
GO:0045499	chemorepellent activity	4/2245	28/18639	0.142857142857143	1.18606426980592	0.440799949638705	0.857370012156412
GO:0004679	AMP-activated protein kinase activity	31/2245	248/18639	0.125	1.03780623608018	0.441404609305867	0.857370012156412
GO:0016791	phosphatase activity	34/2245	273/18639	0.124542124542125	1.03400474803593	0.444928502374841	0.862870672568316
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	21/2245	167/18639	0.125748502994012	1.04402064467946	0.45163183072507	0.865080883466322
GO:0061135	endopeptidase regulator activity	23/2245	184/18639	0.125	1.03780623608018	0.45817275628229	0.865080883466322
GO:0008238	exopeptidase activity	13/2245	102/18639	0.127450980392157	1.0581553779641	0.45871205742568	0.865080883466322
GO:0005003	ephrin receptor activity	7/2245	53/18639	0.132075471698113	1.09654998529226	0.458968371303739	0.865080883466322
GO:0005005	transmembrane-ephrin receptor activity	7/2245	53/18639	0.132075471698113	1.09654998529226	0.458968371303739	0.865080883466322
GO:0005544	calcium-dependent phospholipid binding	7/2245	53/18639	0.132075471698113	1.09654998529226	0.458968371303739	0.865080883466322
GO:0016251	RNA polymerase II general transcription initiation factor activity	7/2245	53/18639	0.132075471698113	1.09654998529226	0.458968371303739	0.865080883466322
GO:0038064	collagen receptor activity	7/2245	53/18639	0.132075471698113	1.09654998529226	0.458968371303739	0.865080883466322
GO:0140303	intramembrane lipid transporter activity	6/2245	45/18639	0.133333333333333	1.10699331848552	0.46198110850512	0.865080883466322
GO:0005539	glycosaminoglycan binding	30/2245	242/18639	0.12396694214876	1.02922932503819	0.462398955551985	0.865080883466322
GO:1901681	sulfur compound binding	34/2245	275/18639	0.123636363636364	1.02648471350476	0.462852435309813	0.865080883466322
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	11/2245	86/18639	0.127906976744186	1.06194126482623	0.464563342726222	0.865080883466322
GO:0023023	MHC protein complex binding	5/2245	37/18639	0.135135135135135	1.12195268765425	0.465212217300491	0.865080883466322
GO:0004629	phospholipase C activity	4/2245	29/18639	0.137931034482759	1.14516550188158	0.468688701002213	0.865080883466322
GO:0106222	lncRNA binding	4/2245	29/18639	0.137931034482759	1.14516550188158	0.468688701002213	0.865080883466322
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	30/2245	243/18639	0.123456790123457	1.02499381341252	0.471940533020353	0.865080883466322
GO:0035613	RNA stem-loop binding	3/2245	21/18639	0.142857142857143	1.18606426980592	0.472382169858953	0.865080883466322
GO:1904047	S-adenosyl-L-methionine binding	3/2245	21/18639	0.142857142857143	1.18606426980592	0.472382169858953	0.865080883466322
GO:0015179	L-amino acid transmembrane transporter activity	8/2245	62/18639	0.129032258064516	1.07128385659889	0.475066251255437	0.865080883466322
GO:0003964	RNA-directed DNA polymerase activity	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0005172	vascular endothelial growth factor receptor binding	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0008035	high-density lipoprotein particle binding	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0015651	quaternary ammonium group transmembrane transporter activity	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0030955	potassium ion binding	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0031432	titin binding	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0031994	insulin-like growth factor I binding	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0035325	Toll-like receptor binding	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0046975	histone H3K36 methyltransferase activity	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0051011	microtubule minus-end binding	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0061459	L-arginine transmembrane transporter activity	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0070700	BMP receptor binding	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0071714	icosanoid transmembrane transporter activity	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0140852	histone ubiquitin ligase activity	2/2245	13/18639	0.153846153846154	1.27729998286791	0.475863132259096	0.865080883466322
GO:0005178	integrin binding	20/2245	161/18639	0.124223602484472	1.03136023461384	0.477401021064167	0.865080883466322
GO:0005319	lipid transporter activity	22/2245	178/18639	0.123595505617978	1.02614549185456	0.482899704228601	0.865080883466322
GO:0140299	molecular sensor activity	9/2245	71/18639	0.126760563380282	1.05242322532074	0.488939439131534	0.865080883466322
GO:0004676	3-phosphoinositide-dependent protein kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:0004711	ribosomal protein S6 kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:0035175	histone H3S10 kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:0035979	histone H2AXS139 kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:0044022	histone H3S28 kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:0044023	histone H4S1 kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:0044024	histone H2AS1 kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:0044025	histone H2BS14 kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:0072354	histone H3T3 kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:0072371	histone H2AS121 kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:0072518	Rho-dependent protein serine/threonine kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:0140823	histone H2BS36 kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:0140855	histone H3S57 kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:0140995	histone H2A kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:0140997	histone H4 kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:0140998	histone H2B kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:1990244	histone H2AT120 kinase activity	30/2245	245/18639	0.122448979591837	1.0166265169765	0.490983729573202	0.865080883466322
GO:0004896	cytokine receptor activity	12/2245	96/18639	0.125	1.03780623608018	0.491987720891819	0.865080883466322
GO:0015291	secondary active transmembrane transporter activity	35/2245	287/18639	0.121951219512195	1.01249388885871	0.495988353895486	0.865080883466322
GO:0008106	alcohol dehydrogenase (NADP+) activity	4/2245	30/18639	0.133333333333333	1.10699331848552	0.49604954538077	0.865080883466322
GO:0015215	nucleotide transmembrane transporter activity	4/2245	30/18639	0.133333333333333	1.10699331848552	0.49604954538077	0.865080883466322
GO:0033612	receptor serine/threonine kinase binding	4/2245	30/18639	0.133333333333333	1.10699331848552	0.49604954538077	0.865080883466322
GO:0035925	mRNA 3'-UTR AU-rich region binding	4/2245	30/18639	0.133333333333333	1.10699331848552	0.49604954538077	0.865080883466322
GO:0070566	adenylyltransferase activity	4/2245	30/18639	0.133333333333333	1.10699331848552	0.49604954538077	0.865080883466322
GO:0004677	DNA-dependent protein kinase activity	30/2245	246/18639	0.121951219512195	1.01249388885871	0.500474742295157	0.865080883466322
GO:0140857	histone H3T45 kinase activity	30/2245	246/18639	0.121951219512195	1.01249388885871	0.500474742295157	0.865080883466322
GO:0141003	histone H2AX kinase activity	43/2245	354/18639	0.121468926553672	1.00848967573893	0.501045508235573	0.865080883466322
GO:0004407	histone deacetylase activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0008093	cytoskeletal anchor activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0031683	G-protein beta/gamma-subunit complex binding	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0032931	histone H3K56 acetyltransferase activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0033558	protein lysine deacetylase activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0034062	5'-3' RNA polymerase activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0043992	histone H3K9 acetyltransferase activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0043993	histone H3K18 acetyltransferase activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0043994	histone H3K23 acetyltransferase activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0043999	histone H2AK5 acetyltransferase activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0044012	histone H2AK9 acetyltransferase activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0044014	histone H2BK5 acetyltransferase activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0044015	histone H2BK12 acetyltransferase activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0044016	histone H3K4 acetyltransferase activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0044017	histone H3K27 acetyltransferase activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0044018	histone H3K36 acetyltransferase activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0097747	RNA polymerase activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0140908	histone H3K122 acetyltransferase activity	3/2245	22/18639	0.136363636363636	1.13215225754201	0.504434295236789	0.865080883466322
GO:0140359	ABC-type transporter activity	6/2245	47/18639	0.127659574468085	1.05988721982656	0.505728920647112	0.865080883466322
GO:0140938	histone H3 methyltransferase activity	6/2245	47/18639	0.127659574468085	1.05988721982656	0.505728920647112	0.865080883466322
GO:0008201	heparin binding	21/2245	172/18639	0.122093023255814	1.01367120733413	0.508620866820555	0.866271326878313
GO:0035403	histone H3T6 kinase activity	30/2245	247/18639	0.121457489878543	1.00839472331677	0.50993842539306	0.866271326878313
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	5/2245	39/18639	0.128205128205128	1.06441665238993	0.513324839286372	0.866271326878313
GO:0004705	JUN kinase activity	2/2245	14/18639	0.142857142857143	1.18606426980592	0.516307423006281	0.866271326878313
GO:0005347	ATP transmembrane transporter activity	2/2245	14/18639	0.142857142857143	1.18606426980592	0.516307423006281	0.866271326878313
GO:0008174	mRNA methyltransferase activity	2/2245	14/18639	0.142857142857143	1.18606426980592	0.516307423006281	0.866271326878313
GO:0008392	arachidonate epoxygenase activity	2/2245	14/18639	0.142857142857143	1.18606426980592	0.516307423006281	0.866271326878313
GO:0008494	translation activator activity	2/2245	14/18639	0.142857142857143	1.18606426980592	0.516307423006281	0.866271326878313
GO:0008559	ABC-type xenobiotic transporter activity	2/2245	14/18639	0.142857142857143	1.18606426980592	0.516307423006281	0.866271326878313
GO:0019992	diacylglycerol binding	2/2245	14/18639	0.142857142857143	1.18606426980592	0.516307423006281	0.866271326878313
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/2245	14/18639	0.142857142857143	1.18606426980592	0.516307423006281	0.866271326878313
GO:0030983	mismatched DNA binding	2/2245	14/18639	0.142857142857143	1.18606426980592	0.516307423006281	0.866271326878313
GO:0043176	amine binding	2/2245	14/18639	0.142857142857143	1.18606426980592	0.516307423006281	0.866271326878313
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/2245	14/18639	0.142857142857143	1.18606426980592	0.516307423006281	0.866271326878313
GO:0004497	monooxygenase activity	13/2245	106/18639	0.122641509433962	1.01822498634282	0.516845122050894	0.866271326878313
GO:0019212	phosphatase inhibitor activity	7/2245	56/18639	0.125	1.03780623608018	0.519181781521077	0.869019706787628
GO:0042626	ATPase-coupled transmembrane transporter activity	12/2245	98/18639	0.122448979591837	1.0166265169765	0.522026906533754	0.869224562837936
GO:0005452	solute:inorganic anion antiporter activity	4/2245	31/18639	0.129032258064516	1.07128385659889	0.522789432340379	0.869224562837936
GO:0017147	Wnt-protein binding	4/2245	31/18639	0.129032258064516	1.07128385659889	0.522789432340379	0.869224562837936
GO:0047499	calcium-independent phospholipase A2 activity	4/2245	31/18639	0.129032258064516	1.07128385659889	0.522789432340379	0.869224562837936
GO:0070273	phosphatidylinositol-4-phosphate binding	4/2245	31/18639	0.129032258064516	1.07128385659889	0.522789432340379	0.869224562837936
GO:0140996	histone H3 kinase activity	43/2245	357/18639	0.120448179271709	1.00001497258146	0.524730305839963	0.870615368866504
GO:0035401	histone H3Y41 kinase activity	14/2245	115/18639	0.121739130434783	1.01073302992156	0.525861228651204	0.870615368866504
GO:0140801	histone H2AXY142 kinase activity	14/2245	115/18639	0.121739130434783	1.01073302992156	0.525861228651204	0.870615368866504
GO:0005516	calmodulin binding	25/2245	207/18639	0.120772946859903	1.0027113392079	0.526418595128584	0.870615368866504
GO:0160215	deacylase activity	8/2245	65/18639	0.123076923076923	1.02183998629433	0.530733072216727	0.876588266297031
GO:0000295	adenine nucleotide transmembrane transporter activity	3/2245	23/18639	0.130434782608696	1.08292824634453	0.535445677756436	0.878553631792469
GO:0008171	O-methyltransferase activity	3/2245	23/18639	0.130434782608696	1.08292824634453	0.535445677756436	0.878553631792469
GO:0016493	C-C chemokine receptor activity	3/2245	23/18639	0.130434782608696	1.08292824634453	0.535445677756436	0.878553631792469
GO:0043274	phospholipase binding	3/2245	23/18639	0.130434782608696	1.08292824634453	0.535445677756436	0.878553631792469
GO:0044013	histone H2B acetyltransferase activity	3/2245	23/18639	0.130434782608696	1.08292824634453	0.535445677756436	0.878553631792469
GO:0004843	cysteine-type deubiquitinase activity	13/2245	108/18639	0.12037037037037	0.999368968077208	0.545277334214583	0.88667688458829
GO:0015106	bicarbonate transmembrane transporter activity	4/2245	32/18639	0.125	1.03780623608018	0.548828930762535	0.88667688458829
GO:0022884	macromolecule transmembrane transporter activity	4/2245	32/18639	0.125	1.03780623608018	0.548828930762535	0.88667688458829
GO:0047498	calcium-dependent phospholipase A2 activity	4/2245	32/18639	0.125	1.03780623608018	0.548828930762535	0.88667688458829
GO:0004089	carbonate dehydratase activity	2/2245	15/18639	0.133333333333333	1.10699331848552	0.55461745788201	0.88667688458829
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/2245	15/18639	0.133333333333333	1.10699331848552	0.55461745788201	0.88667688458829
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/2245	15/18639	0.133333333333333	1.10699331848552	0.55461745788201	0.88667688458829
GO:0004953	icosanoid receptor activity	2/2245	15/18639	0.133333333333333	1.10699331848552	0.55461745788201	0.88667688458829
GO:0005041	low-density lipoprotein particle receptor activity	2/2245	15/18639	0.133333333333333	1.10699331848552	0.55461745788201	0.88667688458829
GO:0005523	tropomyosin binding	2/2245	15/18639	0.133333333333333	1.10699331848552	0.55461745788201	0.88667688458829
GO:0008242	omega peptidase activity	2/2245	15/18639	0.133333333333333	1.10699331848552	0.55461745788201	0.88667688458829
GO:0008252	nucleotidase activity	2/2245	15/18639	0.133333333333333	1.10699331848552	0.55461745788201	0.88667688458829
GO:0015116	sulfate transmembrane transporter activity	2/2245	15/18639	0.133333333333333	1.10699331848552	0.55461745788201	0.88667688458829
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/2245	15/18639	0.133333333333333	1.10699331848552	0.55461745788201	0.88667688458829
GO:0015929	hexosaminidase activity	2/2245	15/18639	0.133333333333333	1.10699331848552	0.55461745788201	0.88667688458829
GO:0017081	chloride channel regulator activity	2/2245	15/18639	0.133333333333333	1.10699331848552	0.55461745788201	0.88667688458829
GO:0048531	beta-1,3-galactosyltransferase activity	2/2245	15/18639	0.133333333333333	1.10699331848552	0.55461745788201	0.88667688458829
GO:0050780	dopamine receptor binding	2/2245	15/18639	0.133333333333333	1.10699331848552	0.55461745788201	0.88667688458829
GO:0141050	histone H3K deacetylase activity	2/2245	15/18639	0.133333333333333	1.10699331848552	0.55461745788201	0.88667688458829
GO:0141051	histone H4K deacetylase activity	2/2245	15/18639	0.133333333333333	1.10699331848552	0.55461745788201	0.88667688458829
GO:0140318	protein transporter activity	5/2245	41/18639	0.121951219512195	1.01249388885871	0.559545927816826	0.892386528492662
GO:1901981	phosphatidylinositol phosphate binding	22/2245	185/18639	0.118918918918919	0.987318365135737	0.559620100466128	0.892386528492662
GO:0019957	C-C chemokine binding	3/2245	24/18639	0.125	1.03780623608018	0.565320001634677	0.895748465106026
GO:0030215	semaphorin receptor binding	3/2245	24/18639	0.125	1.03780623608018	0.565320001634677	0.895748465106026
GO:0060229	lipase activator activity	3/2245	24/18639	0.125	1.03780623608018	0.565320001634677	0.895748465106026
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	3/2245	24/18639	0.125	1.03780623608018	0.565320001634677	0.895748465106026
GO:0140612	DNA damage sensor activity	3/2245	24/18639	0.125	1.03780623608018	0.565320001634677	0.895748465106026
GO:0016500	protein-hormone receptor activity	8/2245	67/18639	0.119402985074627	0.99133730013629	0.566591312091468	0.896623561139671
GO:0048020	CCR chemokine receptor binding	6/2245	50/18639	0.12	0.996293986636971	0.568684483984049	0.89848087880343
GO:0030414	peptidase inhibitor activity	20/2245	169/18639	0.118343195266272	0.982538448359932	0.569206009827354	0.89848087880343
GO:0019956	chemokine binding	4/2245	33/18639	0.121212121212121	1.00635756225957	0.574101580836133	0.903276192012184
GO:0004866	endopeptidase inhibitor activity	19/2245	161/18639	0.118012422360248	0.979792222883149	0.574392703206869	0.903276192012184
GO:0017022	myosin binding	9/2245	76/18639	0.118421052631579	0.983184855233853	0.574417017053458	0.903276192012184
GO:0001786	phosphatidylserine binding	7/2245	59/18639	0.11864406779661	0.985036427465932	0.576759300883885	0.905766953674607
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	27/2245	229/18639	0.117903930131004	0.978891471586544	0.577996245076627	0.905766953674607
GO:0008168	methyltransferase activity	24/2245	204/18639	0.117647058823529	0.976758810428403	0.581581889017722	0.905766953674607
GO:0008307	structural constituent of muscle	5/2245	42/18639	0.119047619047619	0.988386891504931	0.581811812264122	0.905766953674607
GO:0016859	cis-trans isomerase activity	5/2245	42/18639	0.119047619047619	0.988386891504931	0.581811812264122	0.905766953674607
GO:0019894	kinesin binding	5/2245	42/18639	0.119047619047619	0.988386891504931	0.581811812264122	0.905766953674607
GO:0035198	miRNA binding	5/2245	42/18639	0.119047619047619	0.988386891504931	0.581811812264122	0.905766953674607
GO:0042056	chemoattractant activity	5/2245	42/18639	0.119047619047619	0.988386891504931	0.581811812264122	0.905766953674607
GO:1902936	phosphatidylinositol bisphosphate binding	13/2245	111/18639	0.117117117117117	0.972358995967014	0.5867771532342	0.9082964283374
GO:0000062	fatty-acyl-CoA binding	2/2245	16/18639	0.125	1.03780623608018	0.5907204517896	0.9082964283374
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/2245	16/18639	0.125	1.03780623608018	0.5907204517896	0.9082964283374
GO:0004707	MAP kinase activity	2/2245	16/18639	0.125	1.03780623608018	0.5907204517896	0.9082964283374
GO:0008391	arachidonate monooxygenase activity	2/2245	16/18639	0.125	1.03780623608018	0.5907204517896	0.9082964283374
GO:0022858	alanine transmembrane transporter activity	2/2245	16/18639	0.125	1.03780623608018	0.5907204517896	0.9082964283374
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/2245	16/18639	0.125	1.03780623608018	0.5907204517896	0.9082964283374
GO:0070411	I-SMAD binding	2/2245	16/18639	0.125	1.03780623608018	0.5907204517896	0.9082964283374
GO:0140327	flippase activity	2/2245	16/18639	0.125	1.03780623608018	0.5907204517896	0.9082964283374
GO:0140328	floppase activity	2/2245	16/18639	0.125	1.03780623608018	0.5907204517896	0.9082964283374
GO:0000030	mannosyltransferase activity	3/2245	25/18639	0.12	0.996293986636971	0.593984996425297	0.911069238059466
GO:0003707	nuclear steroid receptor activity	3/2245	25/18639	0.12	0.996293986636971	0.593984996425297	0.911069238059466
GO:0019001	guanyl nucleotide binding	47/2245	400/18639	0.1175	0.975537861915368	0.595979429809872	0.911885090764308
GO:0032561	guanyl ribonucleotide binding	47/2245	400/18639	0.1175	0.975537861915368	0.595979429809872	0.911885090764308
GO:0015293	symporter activity	17/2245	146/18639	0.116438356164384	0.966723617170577	0.597553148724798	0.913172520171352
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	4/2245	34/18639	0.117647058823529	0.976758810428403	0.5985531346521	0.913581100258469
GO:0008276	protein methyltransferase activity	11/2245	95/18639	0.115789473684211	0.961336302895323	0.602810037471258	0.9189536879299
GO:0030159	signaling receptor complex adaptor activity	6/2245	52/18639	0.115384615384615	0.957974987150934	0.608388024666487	0.926119305158321
GO:0016798	hydrolase activity, acting on glycosyl bonds	15/2245	130/18639	0.115384615384615	0.957974987150934	0.611002874298256	0.926119305158321
GO:0019905	syntaxin binding	7/2245	61/18639	0.114754098360656	0.952740151155574	0.613231932388547	0.926119305158321
GO:0005525	GTP binding	44/2245	378/18639	0.116402116402116	0.966422738360378	0.620320847732586	0.926119305158321
GO:0001637	G protein-coupled chemoattractant receptor activity	3/2245	26/18639	0.115384615384615	0.957974987150934	0.621389760412667	0.926119305158321
GO:0004435	phosphatidylinositol phospholipase C activity	3/2245	26/18639	0.115384615384615	0.957974987150934	0.621389760412667	0.926119305158321
GO:0004950	chemokine receptor activity	3/2245	26/18639	0.115384615384615	0.957974987150934	0.621389760412667	0.926119305158321
GO:0005160	transforming growth factor beta receptor binding	3/2245	26/18639	0.115384615384615	0.957974987150934	0.621389760412667	0.926119305158321
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	3/2245	26/18639	0.115384615384615	0.957974987150934	0.621389760412667	0.926119305158321
GO:0015216	purine nucleotide transmembrane transporter activity	3/2245	26/18639	0.115384615384615	0.957974987150934	0.621389760412667	0.926119305158321
GO:0070412	R-SMAD binding	3/2245	26/18639	0.115384615384615	0.957974987150934	0.621389760412667	0.926119305158321
GO:0004623	phospholipase A2 activity	4/2245	35/18639	0.114285714285714	0.948851415844734	0.62214071985884	0.926119305158321
GO:0043015	gamma-tubulin binding	4/2245	35/18639	0.114285714285714	0.948851415844734	0.62214071985884	0.926119305158321
GO:0140566	histone reader activity	4/2245	35/18639	0.114285714285714	0.948851415844734	0.62214071985884	0.926119305158321
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/2245	17/18639	0.117647058823529	0.976758810428403	0.624592089525379	0.926119305158321
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/2245	17/18639	0.117647058823529	0.976758810428403	0.624592089525379	0.926119305158321
GO:0016018	cyclosporin A binding	2/2245	17/18639	0.117647058823529	0.976758810428403	0.624592089525379	0.926119305158321
GO:0016805	dipeptidase activity	2/2245	17/18639	0.117647058823529	0.976758810428403	0.624592089525379	0.926119305158321
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/2245	17/18639	0.117647058823529	0.976758810428403	0.624592089525379	0.926119305158321
GO:0032183	SUMO binding	2/2245	17/18639	0.117647058823529	0.976758810428403	0.624592089525379	0.926119305158321
GO:0038191	neuropilin binding	2/2245	17/18639	0.117647058823529	0.976758810428403	0.624592089525379	0.926119305158321
GO:0070403	NAD+ binding	2/2245	17/18639	0.117647058823529	0.976758810428403	0.624592089525379	0.926119305158321
GO:1901567	fatty acid derivative binding	2/2245	17/18639	0.117647058823529	0.976758810428403	0.624592089525379	0.926119305158321
GO:0004864	protein phosphatase inhibitor activity	6/2245	53/18639	0.113207547169811	0.939899987393369	0.627462874031944	0.929271026030682
GO:0000149	SNARE binding	12/2245	106/18639	0.113207547169811	0.939899987393369	0.635386545310103	0.938776092419074
GO:0008013	beta-catenin binding	12/2245	106/18639	0.113207547169811	0.939899987393369	0.635386545310103	0.938776092419074
GO:0051539	4 iron, 4 sulfur cluster binding	5/2245	45/18639	0.111111111111111	0.922494432071269	0.644756355964895	0.946056248837376
GO:0004033	aldo-keto reductase (NADPH) activity	4/2245	36/18639	0.111111111111111	0.922494432071269	0.644831955590781	0.946056248837376
GO:0005484	SNAP receptor activity	4/2245	36/18639	0.111111111111111	0.922494432071269	0.644831955590781	0.946056248837376
GO:0016409	palmitoyltransferase activity	4/2245	36/18639	0.111111111111111	0.922494432071269	0.644831955590781	0.946056248837376
GO:0008170	N-methyltransferase activity	11/2245	98/18639	0.112244897959184	0.931907640561793	0.645039931469084	0.946056248837376
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	6/2245	54/18639	0.111111111111111	0.922494432071269	0.645987433082426	0.946056248837376
GO:0005044	scavenger receptor activity	3/2245	27/18639	0.111111111111111	0.922494432071269	0.647502173269649	0.946056248837376
GO:0005385	zinc ion transmembrane transporter activity	3/2245	27/18639	0.111111111111111	0.922494432071269	0.647502173269649	0.946056248837376
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	3/2245	27/18639	0.111111111111111	0.922494432071269	0.647502173269649	0.946056248837376
GO:0042379	chemokine receptor binding	8/2245	72/18639	0.111111111111111	0.922494432071269	0.650312375212986	0.946056248837376
GO:0008236	serine-type peptidase activity	22/2245	194/18639	0.11340206185567	0.941514935825316	0.651961034193372	0.946056248837376
GO:0015294	solute:monoatomic cation symporter activity	13/2245	116/18639	0.112068965517241	0.930446970278781	0.652020219616031	0.946056248837376
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/2245	18/18639	0.111111111111111	0.922494432071269	0.65624591439	0.946056248837376
GO:0008308	voltage-gated monoatomic anion channel activity	2/2245	18/18639	0.111111111111111	0.922494432071269	0.65624591439	0.946056248837376
GO:0008525	phosphatidylcholine transporter activity	2/2245	18/18639	0.111111111111111	0.922494432071269	0.65624591439	0.946056248837376
GO:0016854	racemase and epimerase activity	2/2245	18/18639	0.111111111111111	0.922494432071269	0.65624591439	0.946056248837376
GO:0017128	phospholipid scramblase activity	2/2245	18/18639	0.111111111111111	0.922494432071269	0.65624591439	0.946056248837376
GO:0030228	lipoprotein particle receptor activity	2/2245	18/18639	0.111111111111111	0.922494432071269	0.65624591439	0.946056248837376
GO:0034185	apolipoprotein binding	2/2245	18/18639	0.111111111111111	0.922494432071269	0.65624591439	0.946056248837376
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	2/2245	18/18639	0.111111111111111	0.922494432071269	0.65624591439	0.946056248837376
GO:0050811	GABA receptor binding	2/2245	18/18639	0.111111111111111	0.922494432071269	0.65624591439	0.946056248837376
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	5/2245	46/18639	0.108695652173913	0.902440205287111	0.664360807420238	0.956648876273714
GO:0019213	deacetylase activity	4/2245	37/18639	0.108108108108108	0.897562150123397	0.666604045080513	0.957667332045391
GO:0043394	proteoglycan binding	4/2245	37/18639	0.108108108108108	0.897562150123397	0.666604045080513	0.957667332045391
GO:0046875	ephrin receptor binding	3/2245	28/18639	0.107142857142857	0.889548202354438	0.672306440105363	0.962532871195623
GO:0051959	dynein light intermediate chain binding	3/2245	28/18639	0.107142857142857	0.889548202354438	0.672306440105363	0.962532871195623
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	3/2245	28/18639	0.107142857142857	0.889548202354438	0.672306440105363	0.962532871195623
GO:0120013	lipid transfer activity	7/2245	65/18639	0.107692307692308	0.894109988007538	0.680740323728025	0.968634183836403
GO:0170055	lipid transmembrane transporter activity	6/2245	56/18639	0.107142857142857	0.889548202354438	0.681314131646792	0.968634183836403
GO:0043495	protein-membrane adaptor activity	5/2245	47/18639	0.106382978723404	0.883239349855471	0.683245555845609	0.968634183836403
GO:0035091	phosphatidylinositol binding	32/2245	284/18639	0.112676056338028	0.935487311396217	0.684386292482476	0.968634183836403
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/2245	19/18639	0.105263157894737	0.873942093541203	0.685724568109204	0.968634183836403
GO:0005520	insulin-like growth factor binding	2/2245	19/18639	0.105263157894737	0.873942093541203	0.685724568109204	0.968634183836403
GO:0008381	mechanosensitive monoatomic ion channel activity	2/2245	19/18639	0.105263157894737	0.873942093541203	0.685724568109204	0.968634183836403
GO:0034987	immunoglobulin receptor binding	2/2245	19/18639	0.105263157894737	0.873942093541203	0.685724568109204	0.968634183836403
GO:0046527	glucosyltransferase activity	2/2245	19/18639	0.105263157894737	0.873942093541203	0.685724568109204	0.968634183836403
GO:0120227	acyl-CoA binding	2/2245	19/18639	0.105263157894737	0.873942093541203	0.685724568109204	0.968634183836403
GO:0140036	ubiquitin-modified protein reader activity	2/2245	19/18639	0.105263157894737	0.873942093541203	0.685724568109204	0.968634183836403
GO:0016757	glycosyltransferase activity	30/2245	267/18639	0.112359550561798	0.932859538049598	0.686483257718819	0.968634183836403
GO:0000146	microfilament motor activity	4/2245	38/18639	0.105263157894737	0.873942093541203	0.687442865032251	0.968634183836403
GO:0005109	frizzled binding	4/2245	38/18639	0.105263157894737	0.873942093541203	0.687442865032251	0.968634183836403
GO:0017171	serine hydrolase activity	22/2245	198/18639	0.111111111111111	0.922494432071269	0.689723235225104	0.970750422489509
GO:0016417	S-acyltransferase activity	3/2245	29/18639	0.103448275862069	0.858874126411182	0.695800794617265	0.974682317706872
GO:0005253	monoatomic anion channel activity	11/2245	103/18639	0.106796116504854	0.886669405583065	0.709651123727971	0.974682317706872
GO:0042054	histone methyltransferase activity	7/2245	67/18639	0.104477611940299	0.867420137619253	0.711536931214184	0.974682317706872
GO:0003924	GTPase activity	37/2245	331/18639	0.11178247734139	0.928068416555084	0.712146004606669	0.974682317706872
GO:0000339	RNA cap binding	2/2245	20/18639	0.1	0.830244988864143	0.713092590329123	0.974682317706872
GO:0042288	MHC class I protein binding	2/2245	20/18639	0.1	0.830244988864143	0.713092590329123	0.974682317706872
GO:0052745	inositol phosphate phosphatase activity	2/2245	20/18639	0.1	0.830244988864143	0.713092590329123	0.974682317706872
GO:0061980	regulatory RNA binding	6/2245	58/18639	0.103448275862069	0.858874126411182	0.714263823274105	0.974682317706872
GO:0001968	fibronectin binding	3/2245	30/18639	0.1	0.830244988864143	0.717995377865764	0.974682317706872
GO:0031210	phosphatidylcholine binding	3/2245	30/18639	0.1	0.830244988864143	0.717995377865764	0.974682317706872
GO:0035254	glutamate receptor binding	5/2245	49/18639	0.102040816326531	0.847188764147084	0.718818791545897	0.974682317706872
GO:0008237	metallopeptidase activity	20/2245	184/18639	0.108695652173913	0.902440205287111	0.721626725886533	0.974682317706872
GO:0000182	rDNA binding	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0004090	carbonyl reductase (NADPH) activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0004382	GDP phosphatase activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0004935	adrenergic receptor activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0004955	prostaglandin receptor activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0005528	FK506 binding	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0008190	eukaryotic initiation factor 4E binding	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0008401	retinoic acid 4-hydroxylase activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0015203	polyamine transmembrane transporter activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0015279	store-operated calcium channel activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0016427	tRNA (cytidine) methyltransferase activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0019531	oxalate transmembrane transporter activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0031434	mitogen-activated protein kinase kinase binding	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0043295	glutathione binding	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0043422	protein kinase B binding	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0050308	sugar-phosphatase activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0051378	serotonin binding	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0070097	delta-catenin binding	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0140940	histone H2A methyltransferase activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0141109	transporter activator activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:1990259	histone H2AQ104 methyltransferase activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:1990757	ubiquitin ligase activator activity	1/2245	10/18639	0.1	0.830244988864143	0.723000115379997	0.974682317706872
GO:0004713	protein tyrosine kinase activity	15/2245	140/18639	0.107142857142857	0.889548202354438	0.724086647416648	0.975092925840778
GO:0008509	monoatomic anion transmembrane transporter activity	16/2245	149/18639	0.10738255033557	0.891538243075589	0.725178582587914	0.975509916383095
GO:0032934	sterol binding	7/2245	68/18639	0.102941176470588	0.854663959124852	0.726165679761488	0.975785132179499
GO:0004252	serine-type endopeptidase activity	19/2245	176/18639	0.107954545454545	0.896287203887427	0.72907710945781	0.978375077714134
GO:0005179	hormone activity	14/2245	132/18639	0.106060606060606	0.880562866977121	0.733567416004043	0.978375077714134
GO:0019199	transmembrane receptor protein kinase activity	8/2245	78/18639	0.102564102564103	0.851533321911941	0.737227913684792	0.978375077714134
GO:0001846	opsonin binding	2/2245	21/18639	0.0952380952380952	0.790709513203945	0.738430529325984	0.978375077714134
GO:0005123	death receptor binding	2/2245	21/18639	0.0952380952380952	0.790709513203945	0.738430529325984	0.978375077714134
GO:0008373	sialyltransferase activity	2/2245	21/18639	0.0952380952380952	0.790709513203945	0.738430529325984	0.978375077714134
GO:0015174	basic amino acid transmembrane transporter activity	2/2245	21/18639	0.0952380952380952	0.790709513203945	0.738430529325984	0.978375077714134
GO:0051428	peptide hormone receptor binding	2/2245	21/18639	0.0952380952380952	0.790709513203945	0.738430529325984	0.978375077714134
GO:0061891	calcium ion sensor activity	2/2245	21/18639	0.0952380952380952	0.790709513203945	0.738430529325984	0.978375077714134
GO:0016279	protein-lysine N-methyltransferase activity	7/2245	69/18639	0.101449275362319	0.842277524934637	0.740276591329796	0.978375077714134
GO:0099106	ion channel regulator activity	17/2245	160/18639	0.10625	0.882135300668151	0.745130361357655	0.978375077714134
GO:0016278	lysine N-methyltransferase activity	7/2245	70/18639	0.1	0.830244988864143	0.753868832727526	0.978375077714134
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0000099	sulfur amino acid transmembrane transporter activity	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0003953	NAD+ nucleosidase activity	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0004016	adenylate cyclase activity	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0004954	prostanoid receptor activity	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0005114	type II transforming growth factor beta receptor binding	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0008199	ferric iron binding	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0008432	JUN kinase binding	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0016594	glycine binding	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0019203	carbohydrate phosphatase activity	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0031731	CCR6 chemokine receptor binding	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0048185	activin binding	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0050998	nitric-oxide synthase binding	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0070697	activin receptor binding	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0097493	structural molecule activity conferring elasticity	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0140031	phosphorylation-dependent protein binding	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:1900750	oligopeptide binding	1/2245	11/18639	0.0909090909090909	0.754768171694675	0.756381657114492	0.978375077714134
GO:0015026	coreceptor activity	6/2245	61/18639	0.0983606557377049	0.816634415276206	0.759140366905876	0.978375077714134
GO:0005243	gap junction channel activity	2/2245	22/18639	0.0909090909090909	0.754768171694675	0.761830152734903	0.978375077714134
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	2/2245	22/18639	0.0909090909090909	0.754768171694675	0.761830152734903	0.978375077714134
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/2245	22/18639	0.0909090909090909	0.754768171694675	0.761830152734903	0.978375077714134
GO:0033691	sialic acid binding	2/2245	22/18639	0.0909090909090909	0.754768171694675	0.761830152734903	0.978375077714134
GO:0050321	tau-protein kinase activity	2/2245	22/18639	0.0909090909090909	0.754768171694675	0.761830152734903	0.978375077714134
GO:0140035	ubiquitin-like protein reader activity	2/2245	22/18639	0.0909090909090909	0.754768171694675	0.761830152734903	0.978375077714134
GO:0140784	metal ion sensor activity	2/2245	22/18639	0.0909090909090909	0.754768171694675	0.761830152734903	0.978375077714134
GO:0019955	cytokine binding	15/2245	144/18639	0.104166666666667	0.864838530066815	0.762980749354973	0.978844644491411
GO:0005496	steroid binding	11/2245	108/18639	0.101851851851852	0.84561989606533	0.766329321127718	0.979061388673325
GO:0005506	iron ion binding	16/2245	154/18639	0.103896103896104	0.862592196222486	0.771767073535386	0.979061388673325
GO:0030971	receptor tyrosine kinase binding	8/2245	81/18639	0.0987654320987654	0.819995050730017	0.774646257324982	0.979061388673325
GO:0030296	protein tyrosine kinase activator activity	3/2245	33/18639	0.0909090909090909	0.754768171694675	0.777021121558652	0.979061388673325
GO:0005246	calcium channel regulator activity	5/2245	53/18639	0.0943396226415094	0.783249989494474	0.78116709479634	0.979061388673325
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	9/2245	91/18639	0.0989010989010989	0.821121417557943	0.782149062584147	0.979061388673325
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	2/2245	23/18639	0.0869565217391304	0.721952164229689	0.783390578923329	0.979061388673325
GO:0099186	structural constituent of postsynapse	2/2245	23/18639	0.0869565217391304	0.721952164229689	0.783390578923329	0.979061388673325
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	2/2245	23/18639	0.0869565217391304	0.721952164229689	0.783390578923329	0.979061388673325
GO:0000340	RNA 7-methylguanosine cap binding	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0003720	telomerase activity	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0003995	acyl-CoA dehydrogenase activity	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0004875	complement receptor activity	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0005165	neurotrophin receptor binding	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0005247	voltage-gated chloride channel activity	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0005436	sodium:phosphate symporter activity	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0005527	macrolide binding	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0015269	calcium-activated potassium channel activity	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0016273	arginine N-methyltransferase activity	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0016274	protein-arginine N-methyltransferase activity	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0035197	siRNA binding	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0035251	UDP-glucosyltransferase activity	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0035259	nuclear glucocorticoid receptor binding	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0036009	protein-glutamine N-methyltransferase activity	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0070410	co-SMAD binding	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	1/2245	12/18639	0.0833333333333333	0.691870824053452	0.785741930883977	0.979061388673325
GO:0046982	protein heterodimerization activity	40/2245	369/18639	0.10840108401084	0.899994567874409	0.785750773210693	0.979061388673325
GO:0005507	copper ion binding	6/2245	63/18639	0.0952380952380952	0.790709513203945	0.786041895635333	0.979061388673325
GO:0004222	metalloendopeptidase activity	11/2245	110/18639	0.1	0.830244988864143	0.786703698035823	0.979061388673325
GO:0015103	inorganic anion transmembrane transporter activity	17/2245	165/18639	0.103030303030303	0.855403927920632	0.788261708703557	0.98002228390163
GO:0043178	alcohol binding	9/2245	92/18639	0.0978260869565217	0.8121961847584	0.792881287814066	0.983900818358264
GO:0043014	alpha-tubulin binding	4/2245	44/18639	0.0909090909090909	0.754768171694675	0.792959360425065	0.983900818358264
GO:0030332	cyclin binding	3/2245	34/18639	0.0882352941176471	0.732569107821302	0.794292217065738	0.984574945010909
GO:0015171	amino acid transmembrane transporter activity	10/2245	102/18639	0.0980392156862745	0.813965675357002	0.799413009606837	0.989938453803104
GO:0015149	hexose transmembrane transporter activity	2/2245	24/18639	0.0833333333333333	0.691870824053452	0.803215176858661	0.990711499053165
GO:0050431	transforming growth factor beta binding	2/2245	24/18639	0.0833333333333333	0.691870824053452	0.803215176858661	0.990711499053165
GO:0055056	D-glucose transmembrane transporter activity	2/2245	24/18639	0.0833333333333333	0.691870824053452	0.803215176858661	0.990711499053165
GO:0070840	dynein complex binding	2/2245	24/18639	0.0833333333333333	0.691870824053452	0.803215176858661	0.990711499053165
GO:0005126	cytokine receptor binding	29/2245	275/18639	0.105454545454545	0.875531079165823	0.804344832495115	0.991124511977676
GO:0004465	lipoprotein lipase activity	1/2245	13/18639	0.0769230769230769	0.638649991433956	0.811565164102717	0.993157290038811
GO:0005035	death receptor activity	1/2245	13/18639	0.0769230769230769	0.638649991433956	0.811565164102717	0.993157290038811
GO:0008253	5'-nucleotidase activity	1/2245	13/18639	0.0769230769230769	0.638649991433956	0.811565164102717	0.993157290038811
GO:0009982	pseudouridine synthase activity	1/2245	13/18639	0.0769230769230769	0.638649991433956	0.811565164102717	0.993157290038811
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/2245	13/18639	0.0769230769230769	0.638649991433956	0.811565164102717	0.993157290038811
GO:0017154	semaphorin receptor activity	1/2245	13/18639	0.0769230769230769	0.638649991433956	0.811565164102717	0.993157290038811
GO:0016247	channel regulator activity	17/2245	168/18639	0.101190476190476	0.840128857779192	0.811569589855292	0.993157290038811
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	28/2245	268/18639	0.104477611940299	0.867420137619253	0.815849860382188	0.997416446957439
GO:0001848	complement binding	2/2245	25/18639	0.08	0.664195991091314	0.821409105591996	0.999073839729689
GO:0004709	MAP kinase kinase kinase activity	2/2245	25/18639	0.08	0.664195991091314	0.821409105591996	0.999073839729689
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/2245	25/18639	0.08	0.664195991091314	0.821409105591996	0.999073839729689
GO:0019707	protein-cysteine S-acyltransferase activity	2/2245	25/18639	0.08	0.664195991091314	0.821409105591996	0.999073839729689
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/2245	25/18639	0.08	0.664195991091314	0.821409105591996	0.999073839729689
GO:0008235	metalloexopeptidase activity	6/2245	66/18639	0.0909090909090909	0.754768171694675	0.822012637981284	0.999073839729689
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/2245	36/18639	0.0833333333333333	0.691870824053452	0.825485916686894	0.999122847316544
GO:0044390	ubiquitin-like protein conjugating enzyme binding	3/2245	36/18639	0.0833333333333333	0.691870824053452	0.825485916686894	0.999122847316544
GO:0141108	transporter regulator activity	17/2245	170/18639	0.1	0.830244988864143	0.826046824049773	0.999122847316544
GO:0099095	ligand-gated monoatomic anion channel activity	4/2245	47/18639	0.0851063829787234	0.706591479884377	0.833861042015914	0.999122847316544
GO:0004065	arylsulfatase activity	1/2245	14/18639	0.0714285714285714	0.593032134902959	0.834277298033212	0.999122847316544
GO:0005545	1-phosphatidylinositol binding	1/2245	14/18639	0.0714285714285714	0.593032134902959	0.834277298033212	0.999122847316544
GO:0016530	metallochaperone activity	1/2245	14/18639	0.0714285714285714	0.593032134902959	0.834277298033212	0.999122847316544
GO:0042813	Wnt receptor activity	1/2245	14/18639	0.0714285714285714	0.593032134902959	0.834277298033212	0.999122847316544
GO:0046030	inositol trisphosphate phosphatase activity	1/2245	14/18639	0.0714285714285714	0.593032134902959	0.834277298033212	0.999122847316544
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/2245	14/18639	0.0714285714285714	0.593032134902959	0.834277298033212	0.999122847316544
GO:1901474	azole transmembrane transporter activity	1/2245	14/18639	0.0714285714285714	0.593032134902959	0.834277298033212	0.999122847316544
GO:1901612	cardiolipin binding	1/2245	14/18639	0.0714285714285714	0.593032134902959	0.834277298033212	0.999122847316544
GO:0005112	Notch binding	2/2245	26/18639	0.0769230769230769	0.638649991433956	0.83807738435694	0.999122847316544
GO:0008157	protein phosphatase 1 binding	2/2245	26/18639	0.0769230769230769	0.638649991433956	0.83807738435694	0.999122847316544
GO:0008198	ferrous iron binding	2/2245	26/18639	0.0769230769230769	0.638649991433956	0.83807738435694	0.999122847316544
GO:0015145	monosaccharide transmembrane transporter activity	2/2245	26/18639	0.0769230769230769	0.638649991433956	0.83807738435694	0.999122847316544
GO:0043548	phosphatidylinositol 3-kinase binding	2/2245	26/18639	0.0769230769230769	0.638649991433956	0.83807738435694	0.999122847316544
GO:0050681	nuclear androgen receptor binding	2/2245	26/18639	0.0769230769230769	0.638649991433956	0.83807738435694	0.999122847316544
GO:0050750	low-density lipoprotein particle receptor binding	2/2245	26/18639	0.0769230769230769	0.638649991433956	0.83807738435694	0.999122847316544
GO:0052742	phosphatidylinositol kinase activity	2/2245	26/18639	0.0769230769230769	0.638649991433956	0.83807738435694	0.999122847316544
GO:0030551	cyclic nucleotide binding	3/2245	37/18639	0.0810810810810811	0.673171612592548	0.839504905358045	0.99986878412749
GO:0008194	UDP-glycosyltransferase activity	14/2245	145/18639	0.096551724137931	0.801615851317103	0.845699040428618	0.999999999971031
GO:0032266	phosphatidylinositol-3-phosphate binding	4/2245	48/18639	0.0833333333333333	0.691870824053452	0.845902945739758	0.999999999971031
GO:0008395	steroid hydroxylase activity	2/2245	27/18639	0.0740740740740741	0.614996288047513	0.853323401243923	0.999999999971031
GO:0015252	proton channel activity	2/2245	27/18639	0.0740740740740741	0.614996288047513	0.853323401243923	0.999999999971031
GO:0015370	solute:sodium symporter activity	7/2245	79/18639	0.0886075949367089	0.735660116715063	0.853588052725162	0.999999999971031
GO:0046332	SMAD binding	7/2245	79/18639	0.0886075949367089	0.735660116715063	0.853588052725162	0.999999999971031
GO:0015459	potassium channel regulator activity	5/2245	59/18639	0.0847457627118644	0.703597448189951	0.853904499422146	0.999999999971031
GO:0031593	polyubiquitin modification-dependent protein binding	5/2245	59/18639	0.0847457627118644	0.703597448189951	0.853904499422146	0.999999999971031
GO:0070888	E-box binding	5/2245	59/18639	0.0847457627118644	0.703597448189951	0.853904499422146	0.999999999971031
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/2245	15/18639	0.0666666666666667	0.553496659242762	0.854253000901155	0.999999999971031
GO:0030553	cGMP binding	1/2245	15/18639	0.0666666666666667	0.553496659242762	0.854253000901155	0.999999999971031
GO:0031005	filamin binding	1/2245	15/18639	0.0666666666666667	0.553496659242762	0.854253000901155	0.999999999971031
GO:0033130	acetylcholine receptor binding	1/2245	15/18639	0.0666666666666667	0.553496659242762	0.854253000901155	0.999999999971031
GO:0047372	monoacylglycerol lipase activity	1/2245	15/18639	0.0666666666666667	0.553496659242762	0.854253000901155	0.999999999971031
GO:0050700	CARD domain binding	1/2245	15/18639	0.0666666666666667	0.553496659242762	0.854253000901155	0.999999999971031
GO:0120283	protein serine/threonine kinase binding	1/2245	15/18639	0.0666666666666667	0.553496659242762	0.854253000901155	0.999999999971031
GO:0140161	monocarboxylate:sodium symporter activity	1/2245	15/18639	0.0666666666666667	0.553496659242762	0.854253000901155	0.999999999971031
GO:0042277	peptide binding	25/2245	249/18639	0.100401606425703	0.833579306088497	0.860255134322462	0.999999999971031
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	51/2245	484/18639	0.105371900826446	0.874844926282464	0.865972363774293	0.999999999971031
GO:0051119	sugar transmembrane transporter activity	2/2245	28/18639	0.0714285714285714	0.593032134902959	0.867247782869967	0.999999999971031
GO:0001217	DNA-binding transcription repressor activity	28/2245	278/18639	0.100719424460432	0.836217974395539	0.868146246361535	0.999999999971031
GO:0070851	growth factor receptor binding	13/2245	139/18639	0.0935251798561151	0.776488119081572	0.868619701361444	0.999999999971031
GO:0004175	endopeptidase activity	42/2245	405/18639	0.103703703703704	0.860994803266518	0.870691995143038	0.999999999971031
GO:0001664	G protein-coupled receptor binding	30/2245	297/18639	0.101010101010101	0.838631301882972	0.871721750508005	0.999999999971031
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/2245	16/18639	0.0625	0.518903118040089	0.871821837508592	0.999999999971031
GO:0015378	sodium:chloride symporter activity	1/2245	16/18639	0.0625	0.518903118040089	0.871821837508592	0.999999999971031
GO:0016722	oxidoreductase activity, acting on metal ions	1/2245	16/18639	0.0625	0.518903118040089	0.871821837508592	0.999999999971031
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/2245	16/18639	0.0625	0.518903118040089	0.871821837508592	0.999999999971031
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/2245	16/18639	0.0625	0.518903118040089	0.871821837508592	0.999999999971031
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/2245	16/18639	0.0625	0.518903118040089	0.871821837508592	0.999999999971031
GO:0005201	extracellular matrix structural constituent	16/2245	168/18639	0.0952380952380952	0.790709513203945	0.872425964297896	0.999999999971031
GO:0003730	mRNA 3'-UTR binding	26/2245	262/18639	0.099236641221374	0.823907240857546	0.878512760090364	0.999999999971031
GO:0005416	amino acid:monoatomic cation symporter activity	2/2245	29/18639	0.0689655172413793	0.572582750940788	0.879947559777574	0.999999999971031
GO:0051861	glycolipid binding	2/2245	29/18639	0.0689655172413793	0.572582750940788	0.879947559777574	0.999999999971031
GO:0099604	ligand-gated calcium channel activity	2/2245	29/18639	0.0689655172413793	0.572582750940788	0.879947559777574	0.999999999971031
GO:0005543	phospholipid binding	52/2245	497/18639	0.104627766599598	0.86866678915363	0.880014879847388	0.999999999971031
GO:0005254	chloride channel activity	7/2245	83/18639	0.0843373493975904	0.700206617114337	0.885951860423883	0.999999999971031
GO:0001530	lipopolysaccharide binding	3/2245	41/18639	0.0731707317073171	0.607496333315226	0.886238537004736	0.999999999971031
GO:0001727	lipid kinase activity	3/2245	41/18639	0.0731707317073171	0.607496333315226	0.886238537004736	0.999999999971031
GO:0042169	SH2 domain binding	3/2245	41/18639	0.0731707317073171	0.607496333315226	0.886238537004736	0.999999999971031
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	4/2245	52/18639	0.0769230769230769	0.638649991433956	0.886933943853567	0.999999999971031
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/2245	17/18639	0.0588235294117647	0.488379405214202	0.887273696757543	0.999999999971031
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/2245	17/18639	0.0588235294117647	0.488379405214202	0.887273696757543	0.999999999971031
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/2245	17/18639	0.0588235294117647	0.488379405214202	0.887273696757543	0.999999999971031
GO:0008484	sulfuric ester hydrolase activity	1/2245	17/18639	0.0588235294117647	0.488379405214202	0.887273696757543	0.999999999971031
GO:0015278	intracellularly gated calcium channel activity	1/2245	17/18639	0.0588235294117647	0.488379405214202	0.887273696757543	0.999999999971031
GO:0019198	transmembrane receptor protein phosphatase activity	1/2245	17/18639	0.0588235294117647	0.488379405214202	0.887273696757543	0.999999999971031
GO:0030548	acetylcholine receptor regulator activity	1/2245	17/18639	0.0588235294117647	0.488379405214202	0.887273696757543	0.999999999971031
GO:0045236	CXCR chemokine receptor binding	1/2245	17/18639	0.0588235294117647	0.488379405214202	0.887273696757543	0.999999999971031
GO:0070402	NADPH binding	1/2245	17/18639	0.0588235294117647	0.488379405214202	0.887273696757543	0.999999999971031
GO:0070492	oligosaccharide binding	1/2245	17/18639	0.0588235294117647	0.488379405214202	0.887273696757543	0.999999999971031
GO:0001216	DNA-binding transcription activator activity	51/2245	491/18639	0.103869653767821	0.862372595357867	0.889337877467575	0.999999999971031
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	17/2245	181/18639	0.0939226519337017	0.779788111087869	0.891273904682691	0.999999999971031
GO:0001965	G-protein alpha-subunit binding	2/2245	30/18639	0.0666666666666667	0.553496659242762	0.891515572771275	0.999999999971031
GO:0051721	protein phosphatase 2A binding	2/2245	30/18639	0.0666666666666667	0.553496659242762	0.891515572771275	0.999999999971031
GO:0098918	structural constituent of synapse	2/2245	30/18639	0.0666666666666667	0.553496659242762	0.891515572771275	0.999999999971031
GO:0048487	beta-tubulin binding	3/2245	42/18639	0.0714285714285714	0.593032134902959	0.895838648657352	0.999999999971031
GO:0004706	JUN kinase kinase kinase activity	1/2245	18/18639	0.0555555555555556	0.461247216035635	0.900863566308575	0.999999999971031
GO:0004970	glutamate-gated receptor activity	1/2245	18/18639	0.0555555555555556	0.461247216035635	0.900863566308575	0.999999999971031
GO:0015373	monoatomic anion:sodium symporter activity	1/2245	18/18639	0.0555555555555556	0.461247216035635	0.900863566308575	0.999999999971031
GO:0017075	syntaxin-1 binding	1/2245	18/18639	0.0555555555555556	0.461247216035635	0.900863566308575	0.999999999971031
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/2245	18/18639	0.0555555555555556	0.461247216035635	0.900863566308575	0.999999999971031
GO:0099602	neurotransmitter receptor regulator activity	1/2245	18/18639	0.0555555555555556	0.461247216035635	0.900863566308575	0.999999999971031
GO:0070325	lipoprotein particle receptor binding	2/2245	31/18639	0.0645161290322581	0.535641928299447	0.902040074300285	0.999999999971031
GO:0015485	cholesterol binding	4/2245	54/18639	0.0740740740740741	0.614996288047513	0.903616535109607	0.999999999971031
GO:0008375	acetylglucosaminyltransferase activity	3/2245	43/18639	0.0697674418604651	0.579240689905216	0.904703536401744	0.999999999971031
GO:0019787	ubiquitin-like protein transferase activity	49/2245	479/18639	0.102296450939457	0.84931115771071	0.906778789500788	0.999999999971031
GO:0120015	sterol transfer activity	2/2245	32/18639	0.0625	0.518903118040089	0.911604486548046	0.999999999971031
GO:0030506	ankyrin binding	1/2245	19/18639	0.0526315789473684	0.436971046770601	0.912815732875207	0.999999999971031
GO:0042834	peptidoglycan binding	1/2245	19/18639	0.0526315789473684	0.436971046770601	0.912815732875207	0.999999999971031
GO:0043395	heparan sulfate proteoglycan binding	1/2245	19/18639	0.0526315789473684	0.436971046770601	0.912815732875207	0.999999999971031
GO:0070003	threonine-type peptidase activity	1/2245	19/18639	0.0526315789473684	0.436971046770601	0.912815732875207	0.999999999971031
GO:0050840	extracellular matrix binding	5/2245	67/18639	0.0746268656716418	0.619585812585181	0.918501868431793	0.999999999971031
GO:0016758	hexosyltransferase activity	18/2245	197/18639	0.0913705583756345	0.758599482210892	0.919148350235849	0.999999999971031
GO:0019239	deaminase activity	2/2245	33/18639	0.0606060606060606	0.503178781129783	0.920287284289297	0.999999999971031
GO:0071889	14-3-3 protein binding	2/2245	33/18639	0.0606060606060606	0.503178781129783	0.920287284289297	0.999999999971031
GO:0140767	enzyme-substrate adaptor activity	12/2245	139/18639	0.0863309352517986	0.716758263767605	0.92029365721737	0.999999999971031
GO:0004715	non-membrane spanning protein tyrosine kinase activity	3/2245	45/18639	0.0666666666666667	0.553496659242762	0.920412921621524	0.999999999971031
GO:0042605	peptide antigen binding	3/2245	45/18639	0.0666666666666667	0.553496659242762	0.920412921621524	0.999999999971031
GO:0046915	transition metal ion transmembrane transporter activity	3/2245	45/18639	0.0666666666666667	0.553496659242762	0.920412921621524	0.999999999971031
GO:0001972	retinoic acid binding	1/2245	20/18639	0.05	0.415122494432071	0.923327477219737	0.999999999971031
GO:0015464	acetylcholine receptor activity	1/2245	20/18639	0.05	0.415122494432071	0.923327477219737	0.999999999971031
GO:0016408	C-acyltransferase activity	1/2245	20/18639	0.05	0.415122494432071	0.923327477219737	0.999999999971031
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/2245	20/18639	0.05	0.415122494432071	0.923327477219737	0.999999999971031
GO:0031418	L-ascorbic acid binding	1/2245	20/18639	0.05	0.415122494432071	0.923327477219737	0.999999999971031
GO:0140939	histone H4 methyltransferase activity	1/2245	20/18639	0.05	0.415122494432071	0.923327477219737	0.999999999971031
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	11/2245	130/18639	0.0846153846153846	0.702514990577351	0.924352781943397	0.999999999971031
GO:0004180	carboxypeptidase activity	3/2245	46/18639	0.0652173913043478	0.541464123172267	0.927345727588092	0.999999999971031
GO:0008175	tRNA methyltransferase activity	2/2245	34/18639	0.0588235294117647	0.488379405214202	0.928161975990769	0.999999999971031
GO:0051427	hormone receptor binding	2/2245	34/18639	0.0588235294117647	0.488379405214202	0.928161975990769	0.999999999971031
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	1/2245	21/18639	0.0476190476190476	0.395354756601973	0.932572324614425	0.999999999971031
GO:0009975	cyclase activity	1/2245	21/18639	0.0476190476190476	0.395354756601973	0.932572324614425	0.999999999971031
GO:0010314	phosphatidylinositol-5-phosphate binding	1/2245	21/18639	0.0476190476190476	0.395354756601973	0.932572324614425	0.999999999971031
GO:0036122	BMP binding	1/2245	21/18639	0.0476190476190476	0.395354756601973	0.932572324614425	0.999999999971031
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	10/2245	122/18639	0.0819672131147541	0.680528679396838	0.932992256661638	0.999999999971031
GO:0005343	organic acid:sodium symporter activity	2/2245	35/18639	0.0571428571428571	0.474425707922367	0.935297161206641	0.999999999971031
GO:0030246	carbohydrate binding	26/2245	280/18639	0.0928571428571429	0.770941775373847	0.940208296076091	0.999999999971031
GO:0008970	phospholipase A1 activity	1/2245	22/18639	0.0454545454545455	0.377384085847338	0.940702904227736	0.999999999971031
GO:0015377	chloride:monoatomic cation symporter activity	1/2245	22/18639	0.0454545454545455	0.377384085847338	0.940702904227736	0.999999999971031
GO:0016881	acid-amino acid ligase activity	1/2245	22/18639	0.0454545454545455	0.377384085847338	0.940702904227736	0.999999999971031
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	4/2245	60/18639	0.0666666666666667	0.553496659242762	0.941313413358572	0.999999999971031
GO:0004190	aspartic-type endopeptidase activity	2/2245	36/18639	0.0555555555555556	0.461247216035635	0.941756646178391	0.999999999971031
GO:0016755	aminoacyltransferase activity	49/2245	496/18639	0.0987903225806452	0.820201702708528	0.945142312181879	0.999999999971031
GO:0140375	immune receptor activity	13/2245	156/18639	0.0833333333333333	0.691870824053452	0.946032108639155	0.999999999971031
GO:0042805	actinin binding	2/2245	37/18639	0.0540540540540541	0.448781075061699	0.947599602796696	0.999999999971031
GO:0070001	aspartic-type peptidase activity	2/2245	37/18639	0.0540540540540541	0.448781075061699	0.947599602796696	0.999999999971031
GO:0005158	insulin receptor binding	1/2245	23/18639	0.0434782608695652	0.360976082114845	0.947853464468845	0.999999999971031
GO:0005212	structural constituent of eye lens	1/2245	23/18639	0.0434782608695652	0.360976082114845	0.947853464468845	0.999999999971031
GO:0005283	amino acid:sodium symporter activity	1/2245	23/18639	0.0434782608695652	0.360976082114845	0.947853464468845	0.999999999971031
GO:0016849	phosphorus-oxygen lyase activity	1/2245	23/18639	0.0434782608695652	0.360976082114845	0.947853464468845	0.999999999971031
GO:0031681	G-protein beta-subunit binding	1/2245	23/18639	0.0434782608695652	0.360976082114845	0.947853464468845	0.999999999971031
GO:0042171	lysophosphatidic acid acyltransferase activity	1/2245	23/18639	0.0434782608695652	0.360976082114845	0.947853464468845	0.999999999971031
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/2245	23/18639	0.0434782608695652	0.360976082114845	0.947853464468845	0.999999999971031
GO:0071617	lysophospholipid acyltransferase activity	1/2245	23/18639	0.0434782608695652	0.360976082114845	0.947853464468845	0.999999999971031
GO:0140103	catalytic activity, acting on a glycoprotein	1/2245	23/18639	0.0434782608695652	0.360976082114845	0.947853464468845	0.999999999971031
GO:0005501	retinoid binding	2/2245	38/18639	0.0526315789473684	0.436971046770601	0.952880758811578	0.999999999971031
GO:0019840	isoprenoid binding	2/2245	38/18639	0.0526315789473684	0.436971046770601	0.952880758811578	0.999999999971031
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/2245	24/18639	0.0416666666666667	0.345935412026726	0.954142085669288	0.999999999971031
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/2245	24/18639	0.0416666666666667	0.345935412026726	0.954142085669288	0.999999999971031
GO:0004806	triacylglycerol lipase activity	1/2245	24/18639	0.0416666666666667	0.345935412026726	0.954142085669288	0.999999999971031
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/2245	24/18639	0.0416666666666667	0.345935412026726	0.954142085669288	0.999999999971031
GO:0030552	cAMP binding	1/2245	24/18639	0.0416666666666667	0.345935412026726	0.954142085669288	0.999999999971031
GO:0035035	histone acetyltransferase binding	1/2245	24/18639	0.0416666666666667	0.345935412026726	0.954142085669288	0.999999999971031
GO:0061659	ubiquitin-like protein ligase activity	35/2245	372/18639	0.0940860215053763	0.781144478770027	0.95520554947642	0.999999999971031
GO:0004842	ubiquitin-protein transferase activity	43/2245	449/18639	0.0957683741648107	0.795112127420003	0.958853595217912	0.999999999971031
GO:0005251	delayed rectifier potassium channel activity	1/2245	25/18639	0.04	0.332097995545657	0.959672626505842	0.999999999971031
GO:0005537	D-mannose binding	1/2245	25/18639	0.04	0.332097995545657	0.959672626505842	0.999999999971031
GO:0015271	outward rectifier potassium channel activity	1/2245	25/18639	0.04	0.332097995545657	0.959672626505842	0.999999999971031
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/2245	25/18639	0.04	0.332097995545657	0.959672626505842	0.999999999971031
GO:0015662	P-type ion transporter activity	1/2245	25/18639	0.04	0.332097995545657	0.959672626505842	0.999999999971031
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/2245	25/18639	0.04	0.332097995545657	0.959672626505842	0.999999999971031
GO:0120020	cholesterol transfer activity	1/2245	25/18639	0.04	0.332097995545657	0.959672626505842	0.999999999971031
GO:0140358	P-type transmembrane transporter activity	1/2245	25/18639	0.04	0.332097995545657	0.959672626505842	0.999999999971031
GO:0015144	carbohydrate transmembrane transporter activity	2/2245	40/18639	0.05	0.415122494432071	0.961955642624373	0.999999999971031
GO:0071855	neuropeptide receptor binding	2/2245	40/18639	0.05	0.415122494432071	0.961955642624373	0.999999999971031
GO:0015108	chloride transmembrane transporter activity	9/2245	121/18639	0.0743801652892562	0.617537595022916	0.963129594922157	0.999999999971031
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/2245	26/18639	0.0384615384615385	0.319324995716978	0.964536436191798	0.999999999971031
GO:0008066	glutamate receptor activity	1/2245	26/18639	0.0384615384615385	0.319324995716978	0.964536436191798	0.999999999971031
GO:0030247	polysaccharide binding	1/2245	26/18639	0.0384615384615385	0.319324995716978	0.964536436191798	0.999999999971031
GO:0051139	metal cation:proton antiporter activity	1/2245	26/18639	0.0384615384615385	0.319324995716978	0.964536436191798	0.999999999971031
GO:0005125	cytokine activity	20/2245	234/18639	0.0854700854700855	0.709611101593284	0.965437717804368	0.999999999971031
GO:0042287	MHC protein binding	2/2245	41/18639	0.0487804878048781	0.404997555543484	0.965838571117688	0.999999999971031
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	4/2245	67/18639	0.0597014925373134	0.495668650068145	0.968025927229367	0.999999999971031
GO:0008374	O-acyltransferase activity	3/2245	55/18639	0.0545454545454545	0.452860903016805	0.96889303674813	0.999999999971031
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/2245	56/18639	0.0535714285714286	0.444774101177219	0.971769140970579	0.999999999971031
GO:0099094	ligand-gated monoatomic cation channel activity	10/2245	136/18639	0.0735294117647059	0.610474256517752	0.97243121706882	0.999999999971031
GO:0005242	inward rectifier potassium channel activity	1/2245	28/18639	0.0357142857142857	0.296516067451479	0.97257556719594	0.999999999971031
GO:0051019	mitogen-activated protein kinase binding	1/2245	28/18639	0.0357142857142857	0.296516067451479	0.97257556719594	0.999999999971031
GO:0051393	alpha-actinin binding	1/2245	28/18639	0.0357142857142857	0.296516067451479	0.97257556719594	0.999999999971031
GO:0042562	hormone binding	6/2245	94/18639	0.0638297872340425	0.529943609913282	0.976305504051835	0.999999999971031
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/2245	30/18639	0.0333333333333333	0.276748329621381	0.978792956440326	0.999999999971031
GO:0031624	ubiquitin conjugating enzyme binding	1/2245	30/18639	0.0333333333333333	0.276748329621381	0.978792956440326	0.999999999971031
GO:0061630	ubiquitin protein ligase activity	31/2245	353/18639	0.0878186968838527	0.729110330163978	0.9799745802121	0.999999999971031
GO:0016411	acylglycerol O-acyltransferase activity	1/2245	31/18639	0.032258064516129	0.267820964149723	0.981351385844994	0.999999999971031
GO:0033218	amide binding	20/2245	247/18639	0.0809716599190283	0.672263148877848	0.982477211710164	0.999999999971031
GO:0015020	glucuronosyltransferase activity	1/2245	34/18639	0.0294117647058824	0.244189702607101	0.987319783896872	0.999999999971031
GO:0052866	phosphatidylinositol phosphate phosphatase activity	1/2245	34/18639	0.0294117647058824	0.244189702607101	0.987319783896872	0.999999999971031
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/2245	36/18639	0.0277777777777778	0.230623608017817	0.99019538145929	0.999999999971031
GO:0051213	dioxygenase activity	5/2245	93/18639	0.0537634408602151	0.446368273582872	0.990602119369814	0.999999999971031
GO:0017046	peptide hormone binding	2/2245	53/18639	0.0377358490566038	0.31329999579779	0.99088877780987	0.999999999971031
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/2245	53/18639	0.0377358490566038	0.31329999579779	0.99088877780987	0.999999999971031
GO:0030280	structural constituent of skin epidermis	1/2245	37/18639	0.027027027027027	0.224390537530849	0.991378597533251	0.999999999971031
GO:0098960	postsynaptic neurotransmitter receptor activity	3/2245	69/18639	0.0434782608695652	0.360976082114845	0.992315996962279	0.999999999971031
GO:0016782	transferase activity, transferring sulphur-containing groups	3/2245	70/18639	0.0428571428571429	0.355819280941775	0.993066570896873	0.999999999971031
GO:0032451	demethylase activity	1/2245	40/18639	0.025	0.207561247216036	0.994138613679258	0.999999999971031
GO:0005518	collagen binding	3/2245	72/18639	0.0416666666666667	0.345935412026726	0.994360576767838	0.999999999971031
GO:0008227	G protein-coupled amine receptor activity	1/2245	41/18639	0.024390243902439	0.202498777771742	0.994846114743297	0.999999999971031
GO:0140828	metal cation:monoatomic cation antiporter activity	1/2245	41/18639	0.024390243902439	0.202498777771742	0.994846114743297	0.999999999971031
GO:0008083	growth factor activity	10/2245	162/18639	0.0617283950617284	0.512496906706261	0.995694643032656	0.999999999971031
GO:0015276	ligand-gated monoatomic ion channel activity	12/2245	186/18639	0.0645161290322581	0.535641928299447	0.996073772814385	0.999999999971031
GO:0030547	signaling receptor inhibitor activity	1/2245	44/18639	0.0227272727272727	0.188692042923669	0.996496366201424	0.999999999971031
GO:0022834	ligand-gated channel activity	12/2245	188/18639	0.0638297872340425	0.529943609913282	0.996602788300835	0.999999999971031
GO:0022824	transmitter-gated monoatomic ion channel activity	2/2245	63/18639	0.0317460317460317	0.263569837734648	0.997067374244001	0.999999999971031
GO:0022835	transmitter-gated channel activity	2/2245	63/18639	0.0317460317460317	0.263569837734648	0.997067374244001	0.999999999971031
GO:0008188	neuropeptide receptor activity	1/2245	48/18639	0.0208333333333333	0.172967706013363	0.997905956204673	0.999999999971031
GO:0038187	pattern recognition receptor activity	1/2245	48/18639	0.0208333333333333	0.172967706013363	0.997905956204673	0.999999999971031
GO:0001540	amyloid-beta binding	3/2245	83/18639	0.036144578313253	0.300088550191859	0.998227775872046	0.999999999971031
GO:0015081	sodium ion transmembrane transporter activity	9/2245	164/18639	0.0548780487804878	0.45562224998642	0.998556296423988	0.999999999971031
GO:0005272	sodium channel activity	1/2245	51/18639	0.0196078431372549	0.1627931350714	0.998576680611265	0.999999999971031
GO:0008146	sulfotransferase activity	1/2245	53/18639	0.0188679245283019	0.156649997898895	0.998899734768146	0.999999999971031
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	2/2245	73/18639	0.0273972602739726	0.227464380510724	0.999075856918668	0.999999999971031
GO:0005267	potassium channel activity	5/2245	124/18639	0.0403225806451613	0.334776205187154	0.999493965728848	0.999999999971031
GO:0030594	neurotransmitter receptor activity	3/2245	97/18639	0.0309278350515464	0.256776800679632	0.999611010161137	0.999999999971031
GO:0008528	G protein-coupled peptide receptor activity	4/2245	122/18639	0.0327868852459016	0.272211471758735	0.999860077932063	0.999999999971031
GO:0001653	peptide receptor activity	4/2245	128/18639	0.03125	0.259451559020045	0.999926099495755	0.999999999971031
GO:0015079	potassium ion transmembrane transporter activity	6/2245	160/18639	0.0375	0.311341870824053	0.999941855347165	0.999999999971031
GO:0005262	calcium channel activity	4/2245	131/18639	0.0305343511450382	0.25350992026386	0.999946418431264	0.999999999971031
GO:0005249	voltage-gated potassium channel activity	2/2245	98/18639	0.0204081632653061	0.169437752829417	0.999951710342549	0.999999999971031
GO:0030527	structural constituent of chromatin	2/2245	98/18639	0.0204081632653061	0.169437752829417	0.999951710342549	0.999999999971031
GO:0015085	calcium ion transmembrane transporter activity	4/2245	147/18639	0.0272108843537415	0.225917003772556	0.999990578647587	0.999999999971031
GO:0005244	voltage-gated monoatomic ion channel activity	5/2245	173/18639	0.0289017341040462	0.239955199093683	0.999996790387592	0.999999999971031
GO:0022832	voltage-gated channel activity	5/2245	175/18639	0.0285714285714286	0.237212853961184	0.999997410122577	0.999999999971031
GO:0005216	monoatomic ion channel activity	26/2245	448/18639	0.0580357142857143	0.481838609608654	0.999997617292988	0.999999999971031
GO:0005261	monoatomic cation channel activity	17/2245	341/18639	0.0498533724340176	0.413905126413209	0.999997813372334	0.999999999971031
GO:0022843	voltage-gated monoatomic cation channel activity	3/2245	143/18639	0.020979020979021	0.174177270391079	0.999997871130805	0.999999999971031
GO:0022836	gated channel activity	15/2245	318/18639	0.0471698113207547	0.391624994747237	0.999998190581969	0.999999999971031
GO:0046873	metal ion transmembrane transporter activity	24/2245	450/18639	0.0533333333333333	0.442797327394209	0.999999669378172	0.999999999971031
GO:0045182	translation regulator activity	15/2245	356/18639	0.0421348314606742	0.349822326768599	0.999999938246616	0.999999999971031
GO:0003823	antigen binding	3/2245	174/18639	0.0172413793103448	0.143145687735197	0.999999943873414	0.999999999971031
GO:0030371	translation repressor activity	8/2245	329/18639	0.0243161094224924	0.201883279966965	0.999999999971031	0.999999999971031