ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0031720 haptoglobin binding 9/970 10/18639 0.9 17.2939175257732 2.57733244429168e-11 1.69559956890389e-08 GO:0005201 extracellular matrix structural constituent 33/970 168/18639 0.196428571428571 3.77446612665685 3.22357332491234e-11 1.69559956890389e-08 GO:0045296 cadherin binding 48/970 334/18639 0.143712574850299 2.76150379653065 1.55776958421283e-10 5.46257867530633e-08 GO:0005344 oxygen carrier activity 9/970 14/18639 0.642857142857143 12.3527982326951 4.26725120700632e-09 1.12228706744266e-06 GO:0051082 unfolded protein binding 24/970 121/18639 0.198347107438017 3.81133168612081 1.27028100685967e-08 2.67267123843275e-06 GO:0004601 peroxidase activity 16/970 57/18639 0.280701754385965 5.39381443298969 1.97548182074103e-08 3.46367812569928e-06 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 16/970 59/18639 0.271186440677966 5.2109732657697 3.39297369633959e-08 5.09915475507036e-06 GO:0009055 electron transfer activity 21/970 116/18639 0.181034482758621 3.47866157127622 5.13830864053532e-07 6.75687586230394e-05 GO:0044183 protein folding chaperone 16/970 75/18639 0.213333333333333 4.09929896907216 1.20673097066999e-06 0.000141053442349426 GO:0003743 translation initiation factor activity 13/970 51/18639 0.254901960784314 4.89805942995755 1.42505191357636e-06 0.000149915461308233 GO:0016860 intramolecular oxidoreductase activity 13/970 53/18639 0.245283018867925 4.7132269986384 2.28519917667573e-06 0.000218548139442079 GO:0004857 enzyme inhibitor activity 45/970 416/18639 0.108173076923077 2.07859585646312 2.81920793311744e-06 0.000247150562136629 GO:0019825 oxygen binding 10/970 34/18639 0.294117647058824 5.6516070345664 5.80992718742332e-06 0.000470157184705333 GO:0016853 isomerase activity 25/970 180/18639 0.138888888888889 2.66881443298969 7.15538985201807e-06 0.000510653309764021 GO:0019838 growth factor binding 21/970 136/18639 0.154411764705882 2.96709369314736 7.28117837116e-06 0.000510653309764021 GO:0016209 antioxidant activity 16/970 86/18639 0.186046511627907 3.57497003116759 7.96739668414085e-06 0.000523856331982261 GO:0005178 integrin binding 23/970 161/18639 0.142857142857143 2.74506627393225 1.02871075325998e-05 0.000636590419076176 GO:0030020 extracellular matrix structural constituent conferring tensile strength 11/970 44/18639 0.25 4.80386597938144 1.12722909492844e-05 0.000658802782147066 GO:0008135 translation factor activity, RNA binding 15/970 83/18639 0.180722891566265 3.47267420196249 2.18449501869425e-05 0.0012095203998244 GO:0180051 translation factor activity 15/970 84/18639 0.178571428571429 3.43133284241532 2.53319613050448e-05 0.00133246116464536 GO:0140662 ATP-dependent protein folding chaperone 10/970 40/18639 0.25 4.80386597938144 2.82506252193714e-05 0.00141522179670375 GO:0022853 active monoatomic ion transmembrane transporter activity 18/970 118/18639 0.152542372881356 2.93117246199546 3.80106894089822e-05 0.00181760205719315 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 13/970 68/18639 0.191176470588235 3.67354457246816 4.12815542862748e-05 0.00188818239605048 GO:0015399 primary active transmembrane transporter activity 22/970 166/18639 0.132530120481928 2.54662774810583 5.16769284650726e-05 0.00226517203105235 GO:0005518 collagen binding 13/970 72/18639 0.180555555555556 3.4694587628866 7.69642964132094e-05 0.00323865759306785 GO:0003735 structural constituent of ribosome 22/970 175/18639 0.125714285714286 2.41565832106038 0.000114574940832287 0.00463274389330467 GO:0008171 O-methyltransferase activity 7/970 23/18639 0.304347826086957 5.84818467055132 0.000118901221596223 0.00463274389330467 GO:0048407 platelet-derived growth factor binding 5/970 11/18639 0.454545454545455 8.73430178069353 0.000134138489726115 0.00503977468542403 GO:0070492 oligosaccharide binding 6/970 17/18639 0.352941176470588 6.78192844147969 0.000147453594380326 0.00534900625131388 GO:0043022 ribosome binding 16/970 112/18639 0.142857142857143 2.74506627393225 0.000221117909333668 0.00775386802063396 GO:0051015 actin filament binding 24/970 209/18639 0.114832535885167 2.20656044985942 0.0002351820943818 0.007981018170634 GO:0003756 protein disulfide isomerase activity 6/970 19/18639 0.315789473684211 6.0680412371134 0.0002955333172878 0.0094212439329323 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 6/970 19/18639 0.315789473684211 6.0680412371134 0.0002955333172878 0.0094212439329323 GO:0005539 glycosaminoglycan binding 26/970 242/18639 0.107438016528926 2.06447132998211 0.00038016439054941 0.0117627334958229 GO:0043024 ribosomal small subunit binding 6/970 20/18639 0.3 5.76463917525773 0.000403704986681745 0.0121342184568342 GO:1901681 sulfur compound binding 28/970 275/18639 0.101818181818182 1.95648359887535 0.000552970086613834 0.0158535587777889 GO:0019212 phosphatase inhibitor activity 10/970 56/18639 0.178571428571429 3.43133284241532 0.000557587143325276 0.0158535587777889 GO:0140104 molecular carrier activity 26/970 249/18639 0.104417670682731 2.0064339833561 0.000588106998939555 0.0162812779706424 GO:0061134 peptidase regulator activity 24/970 226/18639 0.106194690265487 2.04058023902929 0.000740070750207962 0.0199629340825327 GO:0043021 ribonucleoprotein complex binding 20/970 177/18639 0.112994350282486 2.17123886073738 0.000923125050740975 0.0242781888344876 GO:0003779 actin binding 39/970 443/18639 0.0880361173814898 1.69165483698308 0.000968724414717552 0.0248560508361674 GO:0008137 NADH dehydrogenase (ubiquinone) activity 8/970 41/18639 0.195121951219512 3.74935881317576 0.00107749610146486 0.0267613893225732 GO:0019208 phosphatase regulator activity 15/970 117/18639 0.128205128205128 2.46352101506741 0.00109385906926868 0.0267613893225732 GO:0016830 carbon-carbon lyase activity 9/970 51/18639 0.176470588235294 3.39096422073984 0.00114012267222514 0.0272592966177464 GO:0051117 ATPase binding 12/970 84/18639 0.142857142857143 2.74506627393225 0.00130820488885937 0.0305829231795567 GO:0061135 endopeptidase regulator activity 20/970 184/18639 0.108695652173913 2.08863738233976 0.00148904106053721 0.0340537216453292 GO:0015035 protein-disulfide reductase activity 7/970 34/18639 0.205882352941176 3.95612492419648 0.00158151923127142 0.0352285848757845 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 15/970 122/18639 0.122950819672131 2.36255703904005 0.00167684328800958 0.0352285848757845 GO:0003925 G protein activity 9/970 54/18639 0.166666666666667 3.20257731958763 0.00173379977812571 0.0352285848757845 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 9/970 54/18639 0.166666666666667 3.20257731958763 0.00173379977812571 0.0352285848757845 GO:0051287 NAD binding 9/970 54/18639 0.166666666666667 3.20257731958763 0.00173379977812571 0.0352285848757845 GO:0003954 NADH dehydrogenase activity 8/970 44/18639 0.181818181818182 3.49372071227741 0.00174133689500075 0.0352285848757845 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 5/970 18/18639 0.277777777777778 5.33762886597938 0.00183347663758305 0.0357472923573054 GO:0050750 low-density lipoprotein particle receptor binding 6/970 26/18639 0.230769230769231 4.43433782712133 0.00183493706016586 0.0357472923573054 GO:0016651 oxidoreductase activity, acting on NAD(P)H 12/970 88/18639 0.136363636363636 2.62029053420806 0.00196683889470812 0.0376202639496899 GO:0050840 extracellular matrix binding 10/970 67/18639 0.149253731343284 2.86797968918295 0.00231907433137307 0.0435654677965084 GO:0005520 insulin-like growth factor binding 5/970 19/18639 0.263157894736842 5.05670103092783 0.00238274210911707 0.0439762227858097 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 9/970 58/18639 0.155172413793103 2.98170991823676 0.00288464392005983 0.0523214724810852 GO:0030414 peptidase inhibitor activity 18/970 169/18639 0.106508875739645 2.04661745867138 0.00312562113181769 0.05573141407919 GO:0031994 insulin-like growth factor I binding 4/970 13/18639 0.307692307692308 5.91245043616178 0.00357123735806335 0.0626107914390145 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 15/970 132/18639 0.113636363636364 2.18357544517338 0.00363047364807974 0.0626107914390145 GO:0008201 heparin binding 18/970 172/18639 0.104651162790698 2.01092064253177 0.00377416359544825 0.0640390339098638 GO:0001968 fibronectin binding 6/970 30/18639 0.2 3.84309278350515 0.0039631277558737 0.0661779428441131 GO:0004860 protein kinase inhibitor activity 11/970 84/18639 0.130952380952381 2.51631075110457 0.0041028210556492 0.0666264043901594 GO:0015036 disulfide oxidoreductase activity 7/970 40/18639 0.175 3.36270618556701 0.00417998354539023 0.0666264043901594 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 7/970 40/18639 0.175 3.36270618556701 0.00417998354539023 0.0666264043901594 GO:0004866 endopeptidase inhibitor activity 17/970 161/18639 0.105590062111801 2.02896202855862 0.004382553628304 0.0688126330891911 GO:0070325 lipoprotein particle receptor binding 6/970 31/18639 0.193548387096774 3.71912204855338 0.00470170624188602 0.0708257393800557 GO:0030021 extracellular matrix structural constituent conferring compression resistance 5/970 22/18639 0.227272727272727 4.36715089034677 0.00474004973816336 0.0708257393800557 GO:0032036 myosin heavy chain binding 4/970 14/18639 0.285714285714286 5.49013254786451 0.00479580035743755 0.0708257393800557 GO:0002020 protease binding 15/970 136/18639 0.110294117647059 2.1193526379624 0.00481100764642254 0.0708257393800557 GO:0048029 monosaccharide binding 10/970 74/18639 0.135135135135135 2.59668431317916 0.00484738900700001 0.0708257393800557 GO:0003725 double-stranded RNA binding 10/970 75/18639 0.133333333333333 2.5620618556701 0.00533897589310336 0.0769397621855444 GO:0030515 snoRNA binding 6/970 32/18639 0.1875 3.60289948453608 0.005536698311102 0.0787109003145851 GO:0004129 cytochrome-c oxidase activity 4/970 15/18639 0.266666666666667 5.12412371134021 0.00627350047742919 0.0879963000300734 GO:0019210 kinase inhibitor activity 11/970 90/18639 0.122222222222222 2.34855670103093 0.00693855984128518 0.0959012461361662 GO:0001091 RNA polymerase II general transcription initiation factor binding 5/970 24/18639 0.208333333333333 4.00322164948454 0.00701938778753308 0.0959012461361662 GO:0016831 carboxy-lyase activity 6/970 34/18639 0.176470588235294 3.39096422073984 0.00752366111570668 0.101472967868249 GO:0015078 proton transmembrane transporter activity 18/970 185/18639 0.0972972972972973 1.86961270548899 0.00799748519082809 0.104223561027882 GO:0005159 insulin-like growth factor receptor binding 4/970 16/18639 0.25 4.80386597938144 0.00802481791184259 0.104223561027882 GO:0016675 oxidoreductase activity, acting on a heme group of donors 4/970 16/18639 0.25 4.80386597938144 0.00802481791184259 0.104223561027882 GO:0019211 phosphatase activator activity 5/970 25/18639 0.2 3.84309278350515 0.00840531310584264 0.10613293671949 GO:0030145 manganese ion binding 9/970 68/18639 0.132352941176471 2.54322316555488 0.00841936945266991 0.10613293671949 GO:0005525 GTP binding 31/970 378/18639 0.082010582010582 1.57587137947963 0.00847449304604292 0.10613293671949 GO:0000287 magnesium ion binding 21/970 230/18639 0.091304347826087 1.7544554011654 0.00897161312460017 0.11103690596564 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 7/970 46/18639 0.152173913043478 2.92409233527566 0.00916667593662952 0.112131896341096 GO:0004029 aldehyde dehydrogenase (NAD+) activity 4/970 17/18639 0.235294117647059 4.52128562765312 0.010068478526017 0.120364084197385 GO:0051787 misfolded protein binding 4/970 17/18639 0.235294117647059 4.52128562765312 0.010068478526017 0.120364084197385 GO:0030246 carbohydrate binding 24/970 280/18639 0.0857142857142857 1.64703976435935 0.0115643479844111 0.136693191905624 GO:0098641 cadherin binding involved in cell-cell adhesion 4/970 18/18639 0.222222222222222 4.27010309278351 0.0124213362084267 0.143273399764235 GO:0001094 TFIID-class transcription factor complex binding 3/970 10/18639 0.3 5.76463917525773 0.012801995796424 0.143273399764235 GO:0003680 minor groove of adenine-thymine-rich DNA binding 3/970 10/18639 0.3 5.76463917525773 0.012801995796424 0.143273399764235 GO:0005522 profilin binding 3/970 10/18639 0.3 5.76463917525773 0.012801995796424 0.143273399764235 GO:0047429 nucleoside triphosphate diphosphatase activity 3/970 10/18639 0.3 5.76463917525773 0.012801995796424 0.143273399764235 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 8/970 61/18639 0.131147540983607 2.52006084164272 0.0133344571039228 0.14766156708765 GO:0005200 structural constituent of cytoskeleton 12/970 112/18639 0.107142857142857 2.05879970544919 0.013655479180168 0.148296920240168 GO:0046625 sphingolipid binding 5/970 28/18639 0.178571428571429 3.43133284241532 0.0136737654594071 0.148296920240168 GO:0005506 iron ion binding 15/970 154/18639 0.0974025974025974 1.8716360958629 0.0144993782502661 0.155646386931428 GO:0046624 sphingolipid transporter activity 4/970 19/18639 0.210526315789474 4.04536082474227 0.0150982946349092 0.157666419327485 GO:0097001 ceramide binding 4/970 19/18639 0.210526315789474 4.04536082474227 0.0150982946349092 0.157666419327485 GO:0031625 ubiquitin protein ligase binding 25/970 302/18639 0.0827814569536424 1.59068409913293 0.015137175239616 0.157666419327485 GO:0043236 laminin binding 5/970 29/18639 0.172413793103448 3.31301102026306 0.0158320457577764 0.161702059584279 GO:0051861 glycolipid binding 5/970 29/18639 0.172413793103448 3.31301102026306 0.0158320457577764 0.161702059584279 GO:0050997 quaternary ammonium group binding 6/970 40/18639 0.15 2.88231958762887 0.0165037005269309 0.161919978535622 GO:0061791 GTPase motor activity 6/970 40/18639 0.15 2.88231958762887 0.0165037005269309 0.161919978535622 GO:1990606 membrane scission GTPase motor activity 6/970 40/18639 0.15 2.88231958762887 0.0165037005269309 0.161919978535622 GO:0098631 cell adhesion mediator activity 9/970 76/18639 0.118421052631579 2.27551546391753 0.0168754696416297 0.161919978535622 GO:0010854 adenylate cyclase regulator activity 3/970 11/18639 0.272727272727273 5.24058106841612 0.0169307962347133 0.161919978535622 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 3/970 11/18639 0.272727272727273 5.24058106841612 0.0169307962347133 0.161919978535622 GO:0034511 U3 snoRNA binding 3/970 11/18639 0.272727272727273 5.24058106841612 0.0169307962347133 0.161919978535622 GO:0019001 guanyl nucleotide binding 31/970 400/18639 0.0775 1.48919845360825 0.0178268222212328 0.165570560794411 GO:0032561 guanyl ribonucleotide binding 31/970 400/18639 0.0775 1.48919845360825 0.0178268222212328 0.165570560794411 GO:0042288 MHC class I protein binding 4/970 20/18639 0.2 3.84309278350515 0.0181122630061543 0.165570560794411 GO:0016769 transferase activity, transferring nitrogenous groups 5/970 30/18639 0.166666666666667 3.20257731958763 0.0182058293581569 0.165570560794411 GO:0031210 phosphatidylcholine binding 5/970 30/18639 0.166666666666667 3.20257731958763 0.0182058293581569 0.165570560794411 GO:0051540 metal cluster binding 9/970 77/18639 0.116883116883117 2.24596331503548 0.0182568298974826 0.165570560794411 GO:0140318 protein transporter activity 6/970 41/18639 0.146341463414634 2.81201910988182 0.018506838166922 0.166403365398307 GO:0004864 protein phosphatase inhibitor activity 7/970 53/18639 0.132075471698113 2.53789146080529 0.0193203864082445 0.170798710096414 GO:0140296 general transcription initiation factor binding 7/970 53/18639 0.132075471698113 2.53789146080529 0.0193203864082445 0.170798710096414 GO:0046332 SMAD binding 9/970 79/18639 0.113924050632911 2.18910348427509 0.0212629725516686 0.186405392702961 GO:0004252 serine-type endopeptidase activity 16/970 176/18639 0.0909090909090909 1.74686035613871 0.0214954640558989 0.18688618336203 GO:0010853 cyclase activator activity 3/970 12/18639 0.25 4.80386597938144 0.021715148285073 0.187248655704072 GO:0051087 protein-folding chaperone binding 13/970 134/18639 0.0970149253731343 1.86418679796892 0.0225097836255043 0.192522702227891 GO:0000049 tRNA binding 9/970 80/18639 0.1125 2.16173969072165 0.0228924478723005 0.194207645223939 GO:0022804 active transmembrane transporter activity 34/970 457/18639 0.074398249452954 1.42959687789032 0.0233582245184783 0.194207645223939 GO:0031369 translation initiation factor binding 5/970 32/18639 0.15625 3.0024162371134 0.0236298275557645 0.194207645223939 GO:0071813 lipoprotein particle binding 5/970 32/18639 0.15625 3.0024162371134 0.0236298275557645 0.194207645223939 GO:0071814 protein-lipid complex binding 5/970 32/18639 0.15625 3.0024162371134 0.0236298275557645 0.194207645223939 GO:0003924 GTPase activity 26/970 331/18639 0.0785498489425982 1.5093717880836 0.0243760490259695 0.198787624614883 GO:0008236 serine-type peptidase activity 17/970 194/18639 0.0876288659793814 1.68382931236051 0.0250121236828418 0.202405800879612 GO:0030170 pyridoxal phosphate binding 7/970 56/18639 0.125 2.40193298969072 0.0254473510634564 0.204355826860734 GO:0019887 protein kinase regulator activity 21/970 255/18639 0.0823529411764706 1.58244996967859 0.0257256930694188 0.205025978098701 GO:0008035 high-density lipoprotein particle binding 3/970 13/18639 0.230769230769231 4.43433782712133 0.027158321563176 0.21311700920847 GO:0045159 myosin II binding 3/970 13/18639 0.230769230769231 4.43433782712133 0.027158321563176 0.21311700920847 GO:0046906 tetrapyrrole binding 14/970 152/18639 0.0921052631578947 1.76984536082474 0.0273486656303645 0.21311700920847 GO:0070279 vitamin B6 binding 7/970 57/18639 0.12280701754386 2.35979381443299 0.0277542946737047 0.214687632328951 GO:0140101 catalytic activity, acting on a tRNA 13/970 139/18639 0.0935251798561151 1.79712971890529 0.0293260449872038 0.224735776450934 GO:0016887 ATP hydrolysis activity 31/970 417/18639 0.0743405275779376 1.42848772528369 0.0296046696217751 0.224735776450934 GO:0017171 serine hydrolase activity 17/970 198/18639 0.0858585858585859 1.64981255857545 0.0296941757858174 0.224735776450934 GO:0044389 ubiquitin-like protein ligase binding 25/970 322/18639 0.077639751552795 1.4918838445284 0.030364800045217 0.228169783196916 GO:0008237 metallopeptidase activity 16/970 184/18639 0.0869565217391304 1.67090990587181 0.0309067792014751 0.23059526042519 GO:0140098 catalytic activity, acting on RNA 29/970 387/18639 0.0749354005167959 1.43991848477583 0.0315482982705723 0.233724012539733 GO:0008191 metalloendopeptidase inhibitor activity 3/970 14/18639 0.214285714285714 4.11759941089838 0.0332571909829228 0.243128152899477 GO:0004175 endopeptidase activity 30/970 405/18639 0.0740740740740741 1.4233676975945 0.0332798992562022 0.243128152899477 GO:0050431 transforming growth factor beta binding 4/970 24/18639 0.166666666666667 3.20257731958763 0.0337264269183122 0.244691042193548 GO:0020037 heme binding 13/970 142/18639 0.0915492957746479 1.75916218963264 0.0340752414323207 0.245528451964393 GO:0043539 protein serine/threonine kinase activator activity 8/970 73/18639 0.10958904109589 2.10580426493433 0.0354798818670454 0.250739752707399 GO:0001098 basal transcription machinery binding 7/970 60/18639 0.116666666666667 2.24180412371134 0.035513520107797 0.250739752707399 GO:0001099 basal RNA polymerase II transcription machinery binding 7/970 60/18639 0.116666666666667 2.24180412371134 0.035513520107797 0.250739752707399 GO:0005523 tropomyosin binding 3/970 15/18639 0.2 3.84309278350515 0.0400031136092962 0.275054088346272 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 3/970 15/18639 0.2 3.84309278350515 0.0400031136092962 0.275054088346272 GO:0031386 protein tag activity 3/970 15/18639 0.2 3.84309278350515 0.0400031136092962 0.275054088346272 GO:0141047 molecular tag activity 3/970 15/18639 0.2 3.84309278350515 0.0400031136092962 0.275054088346272 GO:0043394 proteoglycan binding 5/970 37/18639 0.135135135135135 2.59668431317916 0.0414066166598448 0.282855589130888 GO:0051536 iron-sulfur cluster binding 8/970 76/18639 0.105263157894737 2.02268041237113 0.0435305532480733 0.291269669706829 GO:0050681 nuclear androgen receptor binding 4/970 26/18639 0.153846153846154 2.95622521808089 0.0437458249179457 0.291269669706829 GO:0070006 metalloaminopeptidase activity 4/970 26/18639 0.153846153846154 2.95622521808089 0.0437458249179457 0.291269669706829 GO:0120014 phospholipid transfer activity 4/970 26/18639 0.153846153846154 2.95622521808089 0.0437458249179457 0.291269669706829 GO:0019207 kinase regulator activity 22/970 287/18639 0.0766550522648084 1.47296239089048 0.0452735730535533 0.299545904731686 GO:0005324 long-chain fatty acid transmembrane transporter activity 3/970 16/18639 0.1875 3.60289948453608 0.0473827203087085 0.311541386029758 GO:0019888 protein phosphatase regulator activity 10/970 107/18639 0.0934579439252336 1.79583774930147 0.0519665465303363 0.339557807142322 GO:0004177 aminopeptidase activity 5/970 40/18639 0.125 2.40193298969072 0.0551113243260966 0.355233646242524 GO:0051537 2 iron, 2 sulfur cluster binding 4/970 28/18639 0.142857142857143 2.74506627393225 0.0552552919945525 0.355233646242524 GO:0030169 low-density lipoprotein particle binding 3/970 17/18639 0.176470588235294 3.39096422073984 0.0553786292621424 0.355233646242524 GO:0048306 calcium-dependent protein binding 8/970 80/18639 0.1 1.92154639175258 0.0560126912223588 0.357123340399524 GO:0016829 lyase activity 16/970 200/18639 0.08 1.53723711340206 0.0582777318921501 0.36932634909965 GO:0004867 serine-type endopeptidase inhibitor activity 9/970 95/18639 0.0947368421052632 1.82041237113402 0.058889667793027 0.370969643821942 GO:0001530 lipopolysaccharide binding 5/970 41/18639 0.121951219512195 2.34334925823485 0.060195280737093 0.372502560796599 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 5/970 41/18639 0.121951219512195 2.34334925823485 0.060195280737093 0.372502560796599 GO:0042287 MHC protein binding 5/970 41/18639 0.121951219512195 2.34334925823485 0.060195280737093 0.372502560796599 GO:0003785 actin monomer binding 4/970 29/18639 0.137931034482759 2.65040881621045 0.0615630113924367 0.378738526227155 GO:0008525 phosphatidylcholine transporter activity 3/970 18/18639 0.166666666666667 3.20257731958763 0.0639700878728856 0.38516448823399 GO:0031690 adrenergic receptor binding 3/970 18/18639 0.166666666666667 3.20257731958763 0.0639700878728856 0.38516448823399 GO:1990381 ubiquitin-specific protease binding 3/970 18/18639 0.166666666666667 3.20257731958763 0.0639700878728856 0.38516448823399 GO:0140313 molecular sequestering activity 6/970 55/18639 0.109090909090909 2.09623242736645 0.0651534983564 0.38516448823399 GO:0008307 structural constituent of muscle 5/970 42/18639 0.119047619047619 2.28755522827688 0.06553654315008 0.38516448823399 GO:0035198 miRNA binding 5/970 42/18639 0.119047619047619 2.28755522827688 0.06553654315008 0.38516448823399 GO:0042056 chemoattractant activity 5/970 42/18639 0.119047619047619 2.28755522827688 0.06553654315008 0.38516448823399 GO:0048487 beta-tubulin binding 5/970 42/18639 0.119047619047619 2.28755522827688 0.06553654315008 0.38516448823399 GO:0098918 structural constituent of synapse 4/970 30/18639 0.133333333333333 2.5620618556701 0.0682333470900182 0.398786006326106 GO:0042626 ATPase-coupled transmembrane transporter activity 9/970 98/18639 0.0918367346938776 1.76468546181359 0.0689488222586488 0.400741221083417 GO:0008200 ion channel inhibitor activity 5/970 43/18639 0.116279069767442 2.23435626947974 0.0711337105375238 0.406708277493873 GO:0008028 monocarboxylic acid transmembrane transporter activity 7/970 70/18639 0.1 1.92154639175258 0.0711352880787762 0.406708277493873 GO:0097110 scaffold protein binding 7/970 70/18639 0.1 1.92154639175258 0.0711352880787762 0.406708277493873 GO:0015245 fatty acid transmembrane transporter activity 3/970 19/18639 0.157894736842105 3.0340206185567 0.0731335491050061 0.411425099777895 GO:0070003 threonine-type peptidase activity 3/970 19/18639 0.157894736842105 3.0340206185567 0.0731335491050061 0.411425099777895 GO:0140036 ubiquitin-modified protein reader activity 3/970 19/18639 0.157894736842105 3.0340206185567 0.0731335491050061 0.411425099777895 GO:0016504 peptidase activator activity 6/970 57/18639 0.105263157894737 2.02268041237113 0.074878699720712 0.419002085671218 GO:0016248 channel inhibitor activity 5/970 44/18639 0.113636363636364 2.18357544517338 0.0769847031730297 0.428507448349351 GO:0005319 lipid transporter activity 14/970 178/18639 0.0786516853932584 1.51132862272675 0.0812908878648539 0.448242578630419 GO:0070717 poly-purine tract binding 4/970 32/18639 0.125 2.40193298969072 0.0826358513161785 0.448242578630419 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 3/970 20/18639 0.15 2.88231958762887 0.0828431878283329 0.448242578630419 GO:0010851 cyclase regulator activity 3/970 20/18639 0.15 2.88231958762887 0.0828431878283329 0.448242578630419 GO:0052745 inositol phosphate phosphatase activity 3/970 20/18639 0.15 2.88231958762887 0.0828431878283329 0.448242578630419 GO:0141110 transporter inhibitor activity 5/970 45/18639 0.111111111111111 2.13505154639175 0.0830867897651441 0.448242578630419 GO:0008238 exopeptidase activity 9/970 102/18639 0.0882352941176471 1.69548211036992 0.0839352023260213 0.450509351260073 GO:0031593 polyubiquitin modification-dependent protein binding 6/970 59/18639 0.101694915254237 1.95411497466364 0.0853830512427012 0.4559541619661 GO:0019842 vitamin binding 12/970 150/18639 0.08 1.53723711340206 0.091868255563082 0.461844684711072 GO:0005528 FK506 binding 2/970 10/18639 0.2 3.84309278350515 0.0922600777849486 0.461844684711072 GO:0008190 eukaryotic initiation factor 4E binding 2/970 10/18639 0.2 3.84309278350515 0.0922600777849486 0.461844684711072 GO:0008239 dipeptidyl-peptidase activity 2/970 10/18639 0.2 3.84309278350515 0.0922600777849486 0.461844684711072 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/970 10/18639 0.2 3.84309278350515 0.0922600777849486 0.461844684711072 GO:0016427 tRNA (cytidine) methyltransferase activity 2/970 10/18639 0.2 3.84309278350515 0.0922600777849486 0.461844684711072 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 2/970 10/18639 0.2 3.84309278350515 0.0922600777849486 0.461844684711072 GO:0030957 Tat protein binding 2/970 10/18639 0.2 3.84309278350515 0.0922600777849486 0.461844684711072 GO:0031957 very long-chain fatty acid-CoA ligase activity 2/970 10/18639 0.2 3.84309278350515 0.0922600777849486 0.461844684711072 GO:0031996 thioesterase binding 2/970 10/18639 0.2 3.84309278350515 0.0922600777849486 0.461844684711072 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/970 10/18639 0.2 3.84309278350515 0.0922600777849486 0.461844684711072 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/970 10/18639 0.2 3.84309278350515 0.0922600777849486 0.461844684711072 GO:0140135 mechanosensitive monoatomic cation channel activity 2/970 10/18639 0.2 3.84309278350515 0.0922600777849486 0.461844684711072 GO:0009931 calcium-dependent protein serine/threonine kinase activity 3/970 21/18639 0.142857142857143 2.74506627393225 0.0930713623182008 0.461844684711072 GO:0072542 protein phosphatase activator activity 3/970 21/18639 0.142857142857143 2.74506627393225 0.0930713623182008 0.461844684711072 GO:0033218 amide binding 18/970 247/18639 0.0728744939271255 1.40031720856463 0.0944472222100683 0.466471726596206 GO:0008376 acetylgalactosaminyltransferase activity 4/970 34/18639 0.117647058823529 2.26064281382656 0.0983992564900825 0.483719709474611 GO:0034062 5'-3' RNA polymerase activity 3/970 22/18639 0.136363636363636 2.62029053420806 0.103789025661354 0.494258249449036 GO:0061133 endopeptidase activator activity 3/970 22/18639 0.136363636363636 2.62029053420806 0.103789025661354 0.494258249449036 GO:0097747 RNA polymerase activity 3/970 22/18639 0.136363636363636 2.62029053420806 0.103789025661354 0.494258249449036 GO:0140035 ubiquitin-like protein reader activity 3/970 22/18639 0.136363636363636 2.62029053420806 0.103789025661354 0.494258249449036 GO:0140517 protein-RNA adaptor activity 3/970 22/18639 0.136363636363636 2.62029053420806 0.103789025661354 0.494258249449036 GO:1901682 sulfur compound transmembrane transporter activity 6/970 63/18639 0.0952380952380952 1.8300441826215 0.10867821476881 0.494258249449036 GO:0000099 sulfur amino acid transmembrane transporter activity 2/970 11/18639 0.181818181818182 3.49372071227741 0.108999918129445 0.494258249449036 GO:0008199 ferric iron binding 2/970 11/18639 0.181818181818182 3.49372071227741 0.108999918129445 0.494258249449036 GO:0008526 phosphatidylinositol transfer activity 2/970 11/18639 0.181818181818182 3.49372071227741 0.108999918129445 0.494258249449036 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/970 11/18639 0.181818181818182 3.49372071227741 0.108999918129445 0.494258249449036 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 2/970 11/18639 0.181818181818182 3.49372071227741 0.108999918129445 0.494258249449036 GO:0034713 type I transforming growth factor beta receptor binding 2/970 11/18639 0.181818181818182 3.49372071227741 0.108999918129445 0.494258249449036 GO:0047676 arachidonate-CoA ligase activity 2/970 11/18639 0.181818181818182 3.49372071227741 0.108999918129445 0.494258249449036 GO:0048185 activin binding 2/970 11/18639 0.181818181818182 3.49372071227741 0.108999918129445 0.494258249449036 GO:0050998 nitric-oxide synthase binding 2/970 11/18639 0.181818181818182 3.49372071227741 0.108999918129445 0.494258249449036 GO:0097493 structural molecule activity conferring elasticity 2/970 11/18639 0.181818181818182 3.49372071227741 0.108999918129445 0.494258249449036 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/970 11/18639 0.181818181818182 3.49372071227741 0.108999918129445 0.494258249449036 GO:0180030 inositol phosphate kinase activity 2/970 11/18639 0.181818181818182 3.49372071227741 0.108999918129445 0.494258249449036 GO:0004022 alcohol dehydrogenase (NAD+) activity 3/970 23/18639 0.130434782608696 2.50636485880771 0.11496609145108 0.506028931341208 GO:0004602 glutathione peroxidase activity 3/970 23/18639 0.130434782608696 2.50636485880771 0.11496609145108 0.506028931341208 GO:0005158 insulin receptor binding 3/970 23/18639 0.130434782608696 2.50636485880771 0.11496609145108 0.506028931341208 GO:0017134 fibroblast growth factor binding 3/970 23/18639 0.130434782608696 2.50636485880771 0.11496609145108 0.506028931341208 GO:0099186 structural constituent of postsynapse 3/970 23/18639 0.130434782608696 2.50636485880771 0.11496609145108 0.506028931341208 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 4/970 36/18639 0.111111111111111 2.13505154639175 0.115443862663393 0.506028931341208 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 4/970 36/18639 0.111111111111111 2.13505154639175 0.115443862663393 0.506028931341208 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 4/970 36/18639 0.111111111111111 2.13505154639175 0.115443862663393 0.506028931341208 GO:0016835 carbon-oxygen lyase activity 7/970 79/18639 0.0886075949367089 1.70263604332507 0.116533659262958 0.508686346658225 GO:0003713 transcription coactivator activity 18/970 256/18639 0.0703125 1.35108730670103 0.120643865186092 0.512128804689135 GO:0003712 transcription coregulator activity 32/970 495/18639 0.0646464646464646 1.24221180880975 0.121332593185465 0.512128804689135 GO:0019843 rRNA binding 6/970 65/18639 0.0923076923076923 1.77373513084853 0.121429395549725 0.512128804689135 GO:0038024 cargo receptor activity 6/970 65/18639 0.0923076923076923 1.77373513084853 0.121429395549725 0.512128804689135 GO:0140658 ATP-dependent chromatin remodeler activity 12/970 158/18639 0.0759493670886076 1.45940232285006 0.121884430901882 0.512128804689135 GO:0005048 signal sequence binding 5/970 51/18639 0.0980392156862745 1.88386901152213 0.124744845902989 0.512128804689135 GO:0005049 nuclear export signal receptor activity 2/970 12/18639 0.166666666666667 3.20257731958763 0.12645687209832 0.512128804689135 GO:0005527 macrolide binding 2/970 12/18639 0.166666666666667 3.20257731958763 0.12645687209832 0.512128804689135 GO:0015132 prostaglandin transmembrane transporter activity 2/970 12/18639 0.166666666666667 3.20257731958763 0.12645687209832 0.512128804689135 GO:0015166 polyol transmembrane transporter activity 2/970 12/18639 0.166666666666667 3.20257731958763 0.12645687209832 0.512128804689135 GO:0016423 tRNA (guanine) methyltransferase activity 2/970 12/18639 0.166666666666667 3.20257731958763 0.12645687209832 0.512128804689135 GO:0031543 peptidyl-proline dioxygenase activity 2/970 12/18639 0.166666666666667 3.20257731958763 0.12645687209832 0.512128804689135 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/970 12/18639 0.166666666666667 3.20257731958763 0.12645687209832 0.512128804689135 GO:0005540 hyaluronic acid binding 3/970 24/18639 0.125 2.40193298969072 0.126571757812904 0.512128804689135 GO:0042625 ATPase-coupled ion transmembrane transporter activity 3/970 24/18639 0.125 2.40193298969072 0.126571757812904 0.512128804689135 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 3/970 24/18639 0.125 2.40193298969072 0.126571757812904 0.512128804689135 GO:0046961 proton-transporting ATPase activity, rotational mechanism 3/970 24/18639 0.125 2.40193298969072 0.126571757812904 0.512128804689135 GO:0048027 mRNA 5'-UTR binding 3/970 24/18639 0.125 2.40193298969072 0.126571757812904 0.512128804689135 GO:0070300 phosphatidic acid binding 3/970 24/18639 0.125 2.40193298969072 0.126571757812904 0.512128804689135 GO:0008235 metalloexopeptidase activity 6/970 66/18639 0.0909090909090909 1.74686035613871 0.128069658643577 0.515100234514301 GO:0001618 virus receptor activity 7/970 81/18639 0.0864197530864197 1.66059564719359 0.128285419622383 0.515100234514301 GO:0019955 cytokine binding 11/970 144/18639 0.0763888888888889 1.46784793814433 0.130615830003591 0.522463320014363 GO:0005109 frizzled binding 4/970 38/18639 0.105263157894737 2.02268041237113 0.133676977940814 0.532682503006578 GO:0140272 exogenous protein binding 7/970 82/18639 0.0853658536585366 1.6403444807644 0.134376306742379 0.533440344740025 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 6/970 67/18639 0.0895522388059701 1.72078781350977 0.134881303898143 0.533440344740025 GO:0005537 D-mannose binding 3/970 25/18639 0.12 2.30585567010309 0.138574793485219 0.542616563353077 GO:0008483 transaminase activity 3/970 25/18639 0.12 2.30585567010309 0.138574793485219 0.542616563353077 GO:0008083 growth factor activity 12/970 162/18639 0.0740740740740741 1.4233676975945 0.138748912112146 0.542616563353077 GO:0005548 phospholipid transporter activity 6/970 68/18639 0.0882352941176471 1.69548211036992 0.141860196096285 0.544895104023362 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 4/970 39/18639 0.102564102564103 1.97081681205393 0.143207447265342 0.544895104023362 GO:0009982 pseudouridine synthase activity 2/970 13/18639 0.153846153846154 2.95622521808089 0.1445111540138 0.544895104023362 GO:0019855 calcium channel inhibitor activity 2/970 13/18639 0.153846153846154 2.95622521808089 0.1445111540138 0.544895104023362 GO:0030955 potassium ion binding 2/970 13/18639 0.153846153846154 2.95622521808089 0.1445111540138 0.544895104023362 GO:0031432 titin binding 2/970 13/18639 0.153846153846154 2.95622521808089 0.1445111540138 0.544895104023362 GO:0039706 co-receptor binding 2/970 13/18639 0.153846153846154 2.95622521808089 0.1445111540138 0.544895104023362 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/970 13/18639 0.153846153846154 2.95622521808089 0.1445111540138 0.544895104023362 GO:0071714 icosanoid transmembrane transporter activity 2/970 13/18639 0.153846153846154 2.95622521808089 0.1445111540138 0.544895104023362 GO:0140666 annealing activity 2/970 13/18639 0.153846153846154 2.95622521808089 0.1445111540138 0.544895104023362 GO:0140713 histone chaperone activity 12/970 164/18639 0.0731707317073171 1.40600955494091 0.147631059860332 0.552285855505845 GO:0015485 cholesterol binding 5/970 54/18639 0.0925925925925926 1.77920962199313 0.148571194969728 0.552285855505845 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 5/970 54/18639 0.0925925925925926 1.77920962199313 0.148571194969728 0.552285855505845 GO:0140463 chromatin-protein adaptor activity 5/970 54/18639 0.0925925925925926 1.77920962199313 0.148571194969728 0.552285855505845 GO:0008143 poly(A) binding 3/970 26/18639 0.115384615384615 2.21716891356067 0.150943789385299 0.557167952397663 GO:0008198 ferrous iron binding 3/970 26/18639 0.115384615384615 2.21716891356067 0.150943789385299 0.557167952397663 GO:0098632 cell-cell adhesion mediator activity 5/970 55/18639 0.0909090909090909 1.74686035613871 0.156912964631061 0.577176359412156 GO:0008559 ABC-type xenobiotic transporter activity 2/970 14/18639 0.142857142857143 2.74506627393225 0.163053481185613 0.580550523053914 GO:0016530 metallochaperone activity 2/970 14/18639 0.142857142857143 2.74506627393225 0.163053481185613 0.580550523053914 GO:0044548 S100 protein binding 2/970 14/18639 0.142857142857143 2.74506627393225 0.163053481185613 0.580550523053914 GO:1990825 sequence-specific mRNA binding 2/970 14/18639 0.142857142857143 2.74506627393225 0.163053481185613 0.580550523053914 GO:0008266 poly(U) RNA binding 3/970 27/18639 0.111111111111111 2.13505154639175 0.163647378818698 0.580550523053914 GO:0008320 protein transmembrane transporter activity 3/970 27/18639 0.111111111111111 2.13505154639175 0.163647378818698 0.580550523053914 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 3/970 27/18639 0.111111111111111 2.13505154639175 0.163647378818698 0.580550523053914 GO:0000510 H3-H4 histone complex chaperone activity 11/970 151/18639 0.0728476821192053 1.39980200723698 0.163900670481951 0.580550523053914 GO:0140584 chromatin extrusion motor activity 11/970 151/18639 0.0728476821192053 1.39980200723698 0.163900670481951 0.580550523053914 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 11/970 151/18639 0.0728476821192053 1.39980200723698 0.163900670481951 0.580550523053914 GO:0140849 ATP-dependent H2AZ histone chaperone activity 11/970 151/18639 0.0728476821192053 1.39980200723698 0.163900670481951 0.580550523053914 GO:0008514 organic anion transmembrane transporter activity 18/970 269/18639 0.0669144981412639 1.2857931245928 0.165380943224318 0.58208975348017 GO:0170055 lipid transmembrane transporter activity 5/970 56/18639 0.0892857142857143 1.71566642120766 0.165441859591797 0.58208975348017 GO:0015616 DNA translocase activity 11/970 152/18639 0.0723684210526316 1.39059278350515 0.168971527267269 0.590558294635106 GO:0140674 ATP-dependent histone chaperone activity 11/970 152/18639 0.0723684210526316 1.39059278350515 0.168971527267269 0.590558294635106 GO:0044325 transmembrane transporter binding 10/970 136/18639 0.0735294117647059 1.4129017586416 0.171314644714442 0.594942967534806 GO:0042379 chemokine receptor binding 6/970 72/18639 0.0833333333333333 1.60128865979381 0.17135714749339 0.594942967534806 GO:0016859 cis-trans isomerase activity 4/970 42/18639 0.0952380952380952 1.8300441826215 0.173290706612079 0.596651617881173 GO:0019894 kinesin binding 4/970 42/18639 0.0952380952380952 1.8300441826215 0.173290706612079 0.596651617881173 GO:0003774 cytoskeletal motor activity 11/970 153/18639 0.0718954248366013 1.3815039417829 0.174117915104106 0.596651617881173 GO:0061775 cohesin loader activity 11/970 153/18639 0.0718954248366013 1.3815039417829 0.174117915104106 0.596651617881173 GO:0016866 intramolecular transferase activity 3/970 28/18639 0.107142857142857 2.05879970544919 0.176654429237595 0.599485353412743 GO:0046875 ephrin receptor binding 3/970 28/18639 0.107142857142857 2.05879970544919 0.176654429237595 0.599485353412743 GO:0097718 disordered domain specific binding 3/970 28/18639 0.107142857142857 2.05879970544919 0.176654429237595 0.599485353412743 GO:0003727 single-stranded RNA binding 7/970 89/18639 0.0786516853932584 1.51132862272675 0.180755420641577 0.600148874385102 GO:0004467 long-chain fatty acid-CoA ligase activity 2/970 15/18639 0.133333333333333 2.5620618556701 0.181984306966585 0.600148874385102 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/970 15/18639 0.133333333333333 2.5620618556701 0.181984306966585 0.600148874385102 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/970 15/18639 0.133333333333333 2.5620618556701 0.181984306966585 0.600148874385102 GO:0004865 protein serine/threonine phosphatase inhibitor activity 2/970 15/18639 0.133333333333333 2.5620618556701 0.181984306966585 0.600148874385102 GO:0015250 water channel activity 2/970 15/18639 0.133333333333333 2.5620618556701 0.181984306966585 0.600148874385102 GO:0033130 acetylcholine receptor binding 2/970 15/18639 0.133333333333333 2.5620618556701 0.181984306966585 0.600148874385102 GO:0050780 dopamine receptor binding 2/970 15/18639 0.133333333333333 2.5620618556701 0.181984306966585 0.600148874385102 GO:0120283 protein serine/threonine kinase binding 2/970 15/18639 0.133333333333333 2.5620618556701 0.181984306966585 0.600148874385102 GO:0061980 regulatory RNA binding 5/970 58/18639 0.0862068965517241 1.65650551013153 0.183028705601516 0.601706869664983 GO:0048156 tau protein binding 4/970 43/18639 0.0930232558139535 1.78748501558379 0.183768347235111 0.60225639031569 GO:0030295 protein kinase activator activity 10/970 139/18639 0.0719424460431655 1.38240747608099 0.188067748757681 0.614432520785963 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 3/970 29/18639 0.103448275862069 1.98780661215784 0.189934208219729 0.618609247824009 GO:0019902 phosphatase binding 13/970 190/18639 0.068421052631579 1.31474226804124 0.191602400536895 0.619808614504559 GO:0070063 RNA polymerase binding 5/970 59/18639 0.0847457627118644 1.62842914555303 0.192069969893998 0.619808614504559 GO:0070888 E-box binding 5/970 59/18639 0.0847457627118644 1.62842914555303 0.192069969893998 0.619808614504559 GO:0140297 DNA-binding transcription factor binding 30/970 488/18639 0.0614754098360656 1.18127851952003 0.195898375148322 0.629988650368206 GO:0000062 fatty-acyl-CoA binding 2/970 16/18639 0.125 2.40193298969072 0.201213105060568 0.629988650368206 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/970 16/18639 0.125 2.40193298969072 0.201213105060568 0.629988650368206 GO:0004708 MAP kinase kinase activity 2/970 16/18639 0.125 2.40193298969072 0.201213105060568 0.629988650368206 GO:0005024 transforming growth factor beta receptor activity 2/970 16/18639 0.125 2.40193298969072 0.201213105060568 0.629988650368206 GO:0005521 lamin binding 2/970 16/18639 0.125 2.40193298969072 0.201213105060568 0.629988650368206 GO:0008142 oxysterol binding 2/970 16/18639 0.125 2.40193298969072 0.201213105060568 0.629988650368206 GO:0015562 efflux transmembrane transporter activity 2/970 16/18639 0.125 2.40193298969072 0.201213105060568 0.629988650368206 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/970 16/18639 0.125 2.40193298969072 0.201213105060568 0.629988650368206 GO:0097027 ubiquitin-protein transferase activator activity 2/970 16/18639 0.125 2.40193298969072 0.201213105060568 0.629988650368206 GO:0017022 myosin binding 6/970 76/18639 0.0789473684210526 1.51701030927835 0.2031412783143 0.631375414399492 GO:0008106 alcohol dehydrogenase (NADP+) activity 3/970 30/18639 0.1 1.92154639175258 0.20345652612303 0.631375414399492 GO:0008187 poly-pyrimidine tract binding 3/970 30/18639 0.1 1.92154639175258 0.20345652612303 0.631375414399492 GO:0046915 transition metal ion transmembrane transporter activity 4/970 45/18639 0.0888888888888889 1.7080412371134 0.205311094263385 0.633393757082348 GO:0051539 4 iron, 4 sulfur cluster binding 4/970 45/18639 0.0888888888888889 1.7080412371134 0.205311094263385 0.633393757082348 GO:0001664 G protein-coupled receptor binding 19/970 297/18639 0.063973063973064 1.22927210246798 0.207267694701317 0.637560277268377 GO:0019905 syntaxin binding 5/970 61/18639 0.0819672131147541 1.5750380260267 0.210605207814857 0.645937838545859 GO:0003724 RNA helicase activity 6/970 77/18639 0.0779220779220779 1.49730887669032 0.211403566964019 0.646501605948106 GO:0003689 DNA clamp loader activity 11/970 160/18639 0.06875 1.3210631443299 0.212142136125336 0.646879788996677 GO:0004222 metalloendopeptidase activity 8/970 110/18639 0.0727272727272727 1.39748828491097 0.213994073144307 0.650229418288636 GO:0030291 protein serine/threonine kinase inhibitor activity 4/970 46/18639 0.0869565217391304 1.67090990587181 0.216346758813111 0.650229418288636 GO:0016878 acid-thiol ligase activity 3/970 31/18639 0.0967741935483871 1.85956102427669 0.217191857670556 0.650229418288636 GO:0042562 hormone binding 7/970 94/18639 0.074468085106383 1.43093880236894 0.217440669007258 0.650229418288636 GO:0019903 protein phosphatase binding 10/970 144/18639 0.0694444444444444 1.33440721649485 0.217521257866766 0.650229418288636 GO:0019199 transmembrane receptor protein kinase activity 6/970 78/18639 0.0769230769230769 1.47811260904044 0.219780733266776 0.650229418288636 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 2/970 17/18639 0.117647058823529 2.26064281382656 0.220657701833691 0.650229418288636 GO:0008429 phosphatidylethanolamine binding 2/970 17/18639 0.117647058823529 2.26064281382656 0.220657701833691 0.650229418288636 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/970 17/18639 0.117647058823529 2.26064281382656 0.220657701833691 0.650229418288636 GO:0016805 dipeptidase activity 2/970 17/18639 0.117647058823529 2.26064281382656 0.220657701833691 0.650229418288636 GO:0031489 myosin V binding 2/970 17/18639 0.117647058823529 2.26064281382656 0.220657701833691 0.650229418288636 GO:1901567 fatty acid derivative binding 2/970 17/18639 0.117647058823529 2.26064281382656 0.220657701833691 0.650229418288636 GO:0035091 phosphatidylinositol binding 18/970 284/18639 0.0633802816901408 1.21788151589952 0.226362577470337 0.662477492235998 GO:0005504 fatty acid binding 4/970 47/18639 0.0851063829787234 1.63535863127879 0.227538993343523 0.662477492235998 GO:0140359 ABC-type transporter activity 4/970 47/18639 0.0851063829787234 1.63535863127879 0.227538993343523 0.662477492235998 GO:0008186 ATP-dependent activity, acting on RNA 6/970 79/18639 0.0759493670886076 1.45940232285006 0.228266794143802 0.662477492235998 GO:0033293 monocarboxylic acid binding 6/970 79/18639 0.0759493670886076 1.45940232285006 0.228266794143802 0.662477492235998 GO:0005507 copper ion binding 5/970 63/18639 0.0793650793650794 1.52503681885125 0.229685355163169 0.662477492235998 GO:0022884 macromolecule transmembrane transporter activity 3/970 32/18639 0.09375 1.80144974226804 0.231111444534802 0.662477492235998 GO:0042910 xenobiotic transmembrane transporter activity 3/970 32/18639 0.09375 1.80144974226804 0.231111444534802 0.662477492235998 GO:0051059 NF-kappaB binding 3/970 32/18639 0.09375 1.80144974226804 0.231111444534802 0.662477492235998 GO:0140142 nucleocytoplasmic carrier activity 3/970 32/18639 0.09375 1.80144974226804 0.231111444534802 0.662477492235998 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 9/970 130/18639 0.0692307692307692 1.3303013481364 0.236074979376404 0.668614612605526 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4/970 48/18639 0.0833333333333333 1.60128865979381 0.238873161160268 0.668614612605526 GO:0003746 translation elongation factor activity 2/970 18/18639 0.111111111111111 2.13505154639175 0.240243653578792 0.668614612605526 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/970 18/18639 0.111111111111111 2.13505154639175 0.240243653578792 0.668614612605526 GO:0005372 water transmembrane transporter activity 2/970 18/18639 0.111111111111111 2.13505154639175 0.240243653578792 0.668614612605526 GO:0016854 racemase and epimerase activity 2/970 18/18639 0.111111111111111 2.13505154639175 0.240243653578792 0.668614612605526 GO:0034185 apolipoprotein binding 2/970 18/18639 0.111111111111111 2.13505154639175 0.240243653578792 0.668614612605526 GO:0035615 clathrin adaptor activity 2/970 18/18639 0.111111111111111 2.13505154639175 0.240243653578792 0.668614612605526 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 2/970 18/18639 0.111111111111111 2.13505154639175 0.240243653578792 0.668614612605526 GO:0070628 proteasome binding 2/970 18/18639 0.111111111111111 2.13505154639175 0.240243653578792 0.668614612605526 GO:1901611 phosphatidylglycerol binding 2/970 18/18639 0.111111111111111 2.13505154639175 0.240243653578792 0.668614612605526 GO:0019209 kinase activator activity 10/970 148/18639 0.0675675675675676 1.29834215658958 0.242322586010589 0.672621003913298 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3/970 33/18639 0.0909090909090909 1.74686035613871 0.245187380818869 0.677000327090422 GO:0140416 transcription regulator inhibitor activity 3/970 33/18639 0.0909090909090909 1.74686035613871 0.245187380818869 0.677000327090422 GO:0001221 transcription coregulator binding 8/970 115/18639 0.0695652173913043 1.33672792469745 0.249654575068674 0.685735281911867 GO:0017124 SH3 domain binding 8/970 115/18639 0.0695652173913043 1.33672792469745 0.249654575068674 0.685735281911867 GO:0016874 ligase activity 11/970 167/18639 0.0658682634730539 1.26568924007655 0.253281610019922 0.693886077450412 GO:0008175 tRNA methyltransferase activity 3/970 34/18639 0.0882352941176471 1.69548211036992 0.259392683173268 0.69749657269147 GO:0052866 phosphatidylinositol phosphate phosphatase activity 3/970 34/18639 0.0882352941176471 1.69548211036992 0.259392683173268 0.69749657269147 GO:0008301 DNA binding, bending 2/970 19/18639 0.105263157894737 2.02268041237113 0.259903665869825 0.69749657269147 GO:0008381 mechanosensitive monoatomic ion channel activity 2/970 19/18639 0.105263157894737 2.02268041237113 0.259903665869825 0.69749657269147 GO:0030506 ankyrin binding 2/970 19/18639 0.105263157894737 2.02268041237113 0.259903665869825 0.69749657269147 GO:0031420 alkali metal ion binding 2/970 19/18639 0.105263157894737 2.02268041237113 0.259903665869825 0.69749657269147 GO:0043395 heparan sulfate proteoglycan binding 2/970 19/18639 0.105263157894737 2.02268041237113 0.259903665869825 0.69749657269147 GO:0120227 acyl-CoA binding 2/970 19/18639 0.105263157894737 2.02268041237113 0.259903665869825 0.69749657269147 GO:0048020 CCR chemokine receptor binding 4/970 50/18639 0.08 1.53723711340206 0.261909403335523 0.701090820124607 GO:0008173 RNA methyltransferase activity 5/970 67/18639 0.0746268656716418 1.43398984459148 0.269194242658645 0.718762292580949 GO:0046943 carboxylic acid transmembrane transporter activity 12/970 188/18639 0.0638297872340425 1.22651897345909 0.274506618522396 0.726210022319659 GO:0140597 protein carrier chaperone 12/970 188/18639 0.0638297872340425 1.22651897345909 0.274506618522396 0.726210022319659 GO:0015631 tubulin binding 23/970 385/18639 0.0597402597402597 1.14793680546258 0.276376872388863 0.726210022319659 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 21/970 349/18639 0.0601719197707736 1.15623135320356 0.276819539017687 0.726210022319659 GO:0032934 sterol binding 5/970 68/18639 0.0735294117647059 1.4129017586416 0.279300119369943 0.726210022319659 GO:0140223 general transcription initiation factor activity 5/970 68/18639 0.0735294117647059 1.4129017586416 0.279300119369943 0.726210022319659 GO:1990841 promoter-specific chromatin binding 5/970 68/18639 0.0735294117647059 1.4129017586416 0.279300119369943 0.726210022319659 GO:0000339 RNA cap binding 2/970 20/18639 0.1 1.92154639175258 0.27957705231888 0.726210022319659 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 2/970 20/18639 0.1 1.92154639175258 0.27957705231888 0.726210022319659 GO:0030742 GTP-dependent protein binding 2/970 20/18639 0.1 1.92154639175258 0.27957705231888 0.726210022319659 GO:0031418 L-ascorbic acid binding 2/970 20/18639 0.1 1.92154639175258 0.27957705231888 0.726210022319659 GO:0005342 organic acid transmembrane transporter activity 12/970 189/18639 0.0634920634920635 1.220029455081 0.280457168113456 0.726701824766885 GO:0005516 calmodulin binding 13/970 207/18639 0.0628019323671498 1.20676826535186 0.282333342817576 0.72976579028032 GO:0016922 nuclear receptor binding 9/970 137/18639 0.0656934306569343 1.2623297464068 0.284344228580678 0.732050694505802 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 4/970 52/18639 0.0769230769230769 1.47811260904044 0.285341579844157 0.732050694505802 GO:0005543 phospholipid binding 29/970 497/18639 0.0583501006036217 1.12122425273289 0.287772205186066 0.732050694505802 GO:0004386 helicase activity 10/970 155/18639 0.0645161290322581 1.23970734951779 0.287930697787875 0.732050694505802 GO:0004033 aldo-keto reductase (NADPH) activity 3/970 36/18639 0.0833333333333333 1.60128865979381 0.288088391183842 0.732050694505802 GO:0005484 SNAP receptor activity 3/970 36/18639 0.0833333333333333 1.60128865979381 0.288088391183842 0.732050694505802 GO:0055106 ubiquitin-protein transferase regulator activity 3/970 36/18639 0.0833333333333333 1.60128865979381 0.288088391183842 0.732050694505802 GO:0002039 p53 binding 5/970 69/18639 0.072463768115942 1.39242492155984 0.289479663792177 0.733813509179205 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 6/970 86/18639 0.0697674418604651 1.34061376168784 0.290203863860343 0.733880924954521 GO:0016251 RNA polymerase II general transcription initiation factor activity 4/970 53/18639 0.0754716981132075 1.45022369188874 0.29717156031352 0.738218761045693 GO:0001846 opsonin binding 2/970 21/18639 0.0952380952380952 1.8300441826215 0.299209230213688 0.738218761045693 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/970 21/18639 0.0952380952380952 1.8300441826215 0.299209230213688 0.738218761045693 GO:0035613 RNA stem-loop binding 2/970 21/18639 0.0952380952380952 1.8300441826215 0.299209230213688 0.738218761045693 GO:0036122 BMP binding 2/970 21/18639 0.0952380952380952 1.8300441826215 0.299209230213688 0.738218761045693 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/970 21/18639 0.0952380952380952 1.8300441826215 0.299209230213688 0.738218761045693 GO:0051010 microtubule plus-end binding 2/970 21/18639 0.0952380952380952 1.8300441826215 0.299209230213688 0.738218761045693 GO:0051428 peptide hormone receptor binding 2/970 21/18639 0.0952380952380952 1.8300441826215 0.299209230213688 0.738218761045693 GO:0140312 cargo adaptor activity 2/970 21/18639 0.0952380952380952 1.8300441826215 0.299209230213688 0.738218761045693 GO:1904047 S-adenosyl-L-methionine binding 2/970 21/18639 0.0952380952380952 1.8300441826215 0.299209230213688 0.738218761045693 GO:0008094 ATP-dependent activity, acting on DNA 13/970 210/18639 0.0619047619047619 1.18952871870398 0.299638223352197 0.738218761045693 GO:0004713 protein tyrosine kinase activity 9/970 140/18639 0.0642857142857143 1.23527982326951 0.305814337170602 0.751674492297834 GO:0000146 microfilament motor activity 3/970 38/18639 0.0789473684210526 1.51701030927835 0.317002996457393 0.775551516914366 GO:0043531 ADP binding 3/970 38/18639 0.0789473684210526 1.51701030927835 0.317002996457393 0.775551516914366 GO:0016881 acid-amino acid ligase activity 2/970 22/18639 0.0909090909090909 1.74686035613871 0.318751250668921 0.778019293976113 GO:0008374 O-acyltransferase activity 4/970 55/18639 0.0727272727272727 1.39748828491097 0.320992658161412 0.781676565707883 GO:0004521 RNA endonuclease activity 5/970 73/18639 0.0684931506849315 1.31612766558396 0.330760669056957 0.801662594832979 GO:0000217 DNA secondary structure binding 3/970 39/18639 0.0769230769230769 1.47811260904044 0.331485958890063 0.801662594832979 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/970 39/18639 0.0769230769230769 1.47811260904044 0.331485958890063 0.801662594832979 GO:0005212 structural constituent of eye lens 2/970 23/18639 0.0869565217391304 1.67090990587181 0.338159361070621 0.810349995094061 GO:0031681 G-protein beta-subunit binding 2/970 23/18639 0.0869565217391304 1.67090990587181 0.338159361070621 0.810349995094061 GO:0042171 lysophosphatidic acid acyltransferase activity 2/970 23/18639 0.0869565217391304 1.67090990587181 0.338159361070621 0.810349995094061 GO:0071617 lysophospholipid acyltransferase activity 2/970 23/18639 0.0869565217391304 1.67090990587181 0.338159361070621 0.810349995094061 GO:0043178 alcohol binding 6/970 92/18639 0.0652173913043478 1.25318242940385 0.345699236763391 0.823411646859916 GO:0015144 carbohydrate transmembrane transporter activity 3/970 40/18639 0.075 1.44115979381443 0.345958125391714 0.823411646859916 GO:0030331 nuclear estrogen receptor binding 3/970 40/18639 0.075 1.44115979381443 0.345958125391714 0.823411646859916 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 8/970 128/18639 0.0625 1.20096649484536 0.349363022297062 0.829638599224626 GO:0019003 GDP binding 5/970 75/18639 0.0666666666666667 1.28103092783505 0.351620598719754 0.833119076245904 GO:0051219 phosphoprotein binding 6/970 93/18639 0.0645161290322581 1.23970734951779 0.355065053861945 0.833656578297993 GO:1902936 phosphatidylinositol bisphosphate binding 7/970 111/18639 0.0630630630630631 1.21178601281694 0.35672130806459 0.833656578297993 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/970 24/18639 0.0833333333333333 1.60128865979381 0.357394597730413 0.833656578297993 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/970 24/18639 0.0833333333333333 1.60128865979381 0.357394597730413 0.833656578297993 GO:0015295 solute:proton symporter activity 2/970 24/18639 0.0833333333333333 1.60128865979381 0.357394597730413 0.833656578297993 GO:0030215 semaphorin receptor binding 2/970 24/18639 0.0833333333333333 1.60128865979381 0.357394597730413 0.833656578297993 GO:0050699 WW domain binding 2/970 24/18639 0.0833333333333333 1.60128865979381 0.357394597730413 0.833656578297993 GO:0015175 neutral L-amino acid transmembrane transporter activity 3/970 41/18639 0.0731707317073171 1.40600955494091 0.360399945396587 0.835111767747159 GO:0016877 ligase activity, forming carbon-sulfur bonds 3/970 41/18639 0.0731707317073171 1.40600955494091 0.360399945396587 0.835111767747159 GO:0017080 sodium channel regulator activity 3/970 41/18639 0.0731707317073171 1.40600955494091 0.360399945396587 0.835111767747159 GO:0016410 N-acyltransferase activity 6/970 94/18639 0.0638297872340425 1.22651897345909 0.364448534647492 0.841368607564257 GO:0008017 microtubule binding 16/970 276/18639 0.0579710144927536 1.11393993724787 0.364699700617207 0.841368607564257 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 10/970 167/18639 0.0598802395209581 1.15062658188777 0.37059248235324 0.844692592936244 GO:0008168 methyltransferase activity 12/970 204/18639 0.0588235294117647 1.13032140691328 0.373495156902966 0.844692592936244 GO:0001848 complement binding 2/970 25/18639 0.08 1.53723711340206 0.376422406795212 0.844692592936244 GO:0015645 fatty acid ligase activity 2/970 25/18639 0.08 1.53723711340206 0.376422406795212 0.844692592936244 GO:0015662 P-type ion transporter activity 2/970 25/18639 0.08 1.53723711340206 0.376422406795212 0.844692592936244 GO:0017025 TBP-class protein binding 2/970 25/18639 0.08 1.53723711340206 0.376422406795212 0.844692592936244 GO:0047617 fatty acyl-CoA hydrolase activity 2/970 25/18639 0.08 1.53723711340206 0.376422406795212 0.844692592936244 GO:0120515 fatty acid-CoA ligase activity 2/970 25/18639 0.08 1.53723711340206 0.376422406795212 0.844692592936244 GO:0140358 P-type transmembrane transporter activity 2/970 25/18639 0.08 1.53723711340206 0.376422406795212 0.844692592936244 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/970 60/18639 0.0666666666666667 1.28103092783505 0.38090358676522 0.844692592936244 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 4/970 60/18639 0.0666666666666667 1.28103092783505 0.38090358676522 0.844692592936244 GO:0005179 hormone activity 8/970 132/18639 0.0606060606060606 1.16457357075914 0.381182275237445 0.844692592936244 GO:0016407 acetyltransferase activity 6/970 96/18639 0.0625 1.20096649484536 0.383245894139625 0.844692592936244 GO:0004712 protein serine/threonine/tyrosine kinase activity 3/970 43/18639 0.0697674418604651 1.34061376168784 0.38911981000434 0.844692592936244 GO:0016836 hydro-lyase activity 4/970 61/18639 0.0655737704918033 1.26003042082136 0.392854350200333 0.844692592936244 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/970 26/18639 0.0769230769230769 1.47811260904044 0.395212291579372 0.844692592936244 GO:0005160 transforming growth factor beta receptor binding 2/970 26/18639 0.0769230769230769 1.47811260904044 0.395212291579372 0.844692592936244 GO:0016289 acyl-CoA hydrolase activity 2/970 26/18639 0.0769230769230769 1.47811260904044 0.395212291579372 0.844692592936244 GO:0001046 core promoter sequence-specific DNA binding 3/970 44/18639 0.0681818181818182 1.31014526710403 0.403364183055293 0.844692592936244 GO:0016790 thiolester hydrolase activity 3/970 44/18639 0.0681818181818182 1.31014526710403 0.403364183055293 0.844692592936244 GO:0030547 signaling receptor inhibitor activity 3/970 44/18639 0.0681818181818182 1.31014526710403 0.403364183055293 0.844692592936244 GO:0043014 alpha-tubulin binding 3/970 44/18639 0.0681818181818182 1.31014526710403 0.403364183055293 0.844692592936244 GO:0001671 ATPase activator activity 2/970 27/18639 0.0740740740740741 1.4233676975945 0.413737484600226 0.844692592936244 GO:0004364 glutathione transferase activity 2/970 27/18639 0.0740740740740741 1.4233676975945 0.413737484600226 0.844692592936244 GO:0004683 calcium/calmodulin-dependent protein kinase activity 2/970 27/18639 0.0740740740740741 1.4233676975945 0.413737484600226 0.844692592936244 GO:0005044 scavenger receptor activity 2/970 27/18639 0.0740740740740741 1.4233676975945 0.413737484600226 0.844692592936244 GO:0016405 CoA-ligase activity 2/970 27/18639 0.0740740740740741 1.4233676975945 0.413737484600226 0.844692592936244 GO:0023026 MHC class II protein complex binding 2/970 27/18639 0.0740740740740741 1.4233676975945 0.413737484600226 0.844692592936244 GO:0035255 ionotropic glutamate receptor binding 2/970 27/18639 0.0740740740740741 1.4233676975945 0.413737484600226 0.844692592936244 GO:0004090 carbonyl reductase (NADPH) activity 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0008140 cAMP response element binding protein binding 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0008519 ammonium channel activity 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0016868 intramolecular phosphotransferase activity 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0019531 oxalate transmembrane transporter activity 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0031419 cobalamin binding 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0031434 mitogen-activated protein kinase kinase binding 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0032052 bile acid binding 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0032356 oxidized DNA binding 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0033204 ribonuclease P RNA binding 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0035374 chondroitin sulfate binding 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0042975 peroxisome proliferator activated receptor binding 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0045322 unmethylated CpG binding 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0070739 protein-glutamic acid ligase activity 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0070740 tubulin-glutamic acid ligase activity 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0097177 mitochondrial ribosome binding 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0140940 histone H2A methyltransferase activity 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:1990259 histone H2AQ104 methyltransferase activity 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:1990757 ubiquitin ligase activator activity 1/970 10/18639 0.1 1.92154639175258 0.414083076523472 0.844692592936244 GO:0015101 organic cation transmembrane transporter activity 5/970 81/18639 0.0617283950617284 1.18613974799542 0.414316899196865 0.844692592936244 GO:0008009 chemokine activity 3/970 45/18639 0.0666666666666667 1.28103092783505 0.417510832254715 0.849557825013463 GO:0004180 carboxypeptidase activity 3/970 46/18639 0.0652173913043478 1.25318242940385 0.431545535052967 0.854380203953617 GO:0045499 chemorepellent activity 2/970 28/18639 0.0714285714285714 1.37253313696613 0.431974642705044 0.854380203953617 GO:0120013 lipid transfer activity 4/970 65/18639 0.0615384615384615 1.18249008723236 0.440207220068215 0.854380203953617 GO:0160215 deacylase activity 4/970 65/18639 0.0615384615384615 1.18249008723236 0.440207220068215 0.854380203953617 GO:0016741 transferase activity, transferring one-carbon groups 12/970 215/18639 0.0558139534883721 1.07249100935028 0.443950368190646 0.854380203953617 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0002162 dystroglycan binding 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0005225 volume-sensitive anion channel activity 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0005536 D-glucose binding 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0008271 secondary active sulfate transmembrane transporter activity 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0008432 JUN kinase binding 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0015173 aromatic amino acid transmembrane transporter activity 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0015217 ADP transmembrane transporter activity 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0031731 CCR6 chemokine receptor binding 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0032404 mismatch repair complex binding 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0032794 GTPase activating protein binding 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0042608 T cell receptor binding 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0043855 cyclic nucleotide-activated monoatomic ion channel activity 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0050786 RAGE receptor binding 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0070990 snRNP binding 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0140537 transcription regulator activator activity 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/970 11/18639 0.0909090909090909 1.74686035613871 0.444591392362874 0.854380203953617 GO:0001784 phosphotyrosine residue binding 3/970 47/18639 0.0638297872340425 1.22651897345909 0.445455071987702 0.854380203953617 GO:0004181 metallocarboxypeptidase activity 2/970 29/18639 0.0689655172413793 1.32520440810523 0.44990356377803 0.854380203953617 GO:0106222 lncRNA binding 2/970 29/18639 0.0689655172413793 1.32520440810523 0.44990356377803 0.854380203953617 GO:0046982 protein heterodimerization activity 20/970 369/18639 0.0542005420054201 1.04148855921549 0.458528756103451 0.854380203953617 GO:0001965 G-protein alpha-subunit binding 2/970 30/18639 0.0666666666666667 1.28103092783505 0.46750692361053 0.854380203953617 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/970 30/18639 0.0666666666666667 1.28103092783505 0.46750692361053 0.854380203953617 GO:0048019 receptor antagonist activity 2/970 30/18639 0.0666666666666667 1.28103092783505 0.46750692361053 0.854380203953617 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0004000 adenosine deaminase activity 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0004526 ribonuclease P activity 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0004859 phospholipase inhibitor activity 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0005025 transforming growth factor beta receptor activity, type I 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0005026 transforming growth factor beta receptor activity, type II 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0005078 MAP-kinase scaffold activity 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0005095 GTPase inhibitor activity 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0005165 neurotrophin receptor binding 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0008179 adenylate cyclase binding 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0008603 cAMP-dependent protein kinase regulator activity 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0015368 calcium:monoatomic cation antiporter activity 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0016208 AMP binding 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0016361 activin receptor activity, type I 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0016362 activin receptor activity, type II 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0017002 activin receptor activity 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0017166 vinculin binding 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0034452 dynactin binding 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0035251 UDP-glucosyltransferase activity 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0035259 nuclear glucocorticoid receptor binding 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0035497 cAMP response element binding 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0036009 protein-glutamine N-methyltransferase activity 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0070008 serine-type exopeptidase activity 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0097371 MDM2/MDM4 family protein binding 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0097677 STAT family protein binding 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:1990459 transferrin receptor binding 1/970 12/18639 0.0833333333333333 1.60128865979381 0.473512712386924 0.854380203953617 GO:0051020 GTPase binding 17/970 315/18639 0.053968253968254 1.03702503681885 0.474294713981856 0.854380203953617 GO:0000149 SNARE binding 6/970 106/18639 0.0566037735849057 1.08766776891655 0.476475514255577 0.856841437601482 GO:0140097 catalytic activity, acting on DNA 18/970 336/18639 0.0535714285714286 1.02939985272459 0.484279935375365 0.858159342259962 GO:0005310 dicarboxylic acid transmembrane transporter activity 2/970 31/18639 0.0645161290322581 1.23970734951779 0.48477003160639 0.858159342259962 GO:0005452 solute:inorganic anion antiporter activity 2/970 31/18639 0.0645161290322581 1.23970734951779 0.48477003160639 0.858159342259962 GO:0016411 acylglycerol O-acyltransferase activity 2/970 31/18639 0.0645161290322581 1.23970734951779 0.48477003160639 0.858159342259962 GO:0017147 Wnt-protein binding 2/970 31/18639 0.0645161290322581 1.23970734951779 0.48477003160639 0.858159342259962 GO:0047499 calcium-independent phospholipase A2 activity 2/970 31/18639 0.0645161290322581 1.23970734951779 0.48477003160639 0.858159342259962 GO:0072349 modified amino acid transmembrane transporter activity 2/970 31/18639 0.0645161290322581 1.23970734951779 0.48477003160639 0.858159342259962 GO:0005007 fibroblast growth factor receptor activity 3/970 50/18639 0.06 1.15292783505155 0.486314953126574 0.858159342259962 GO:0008080 N-acetyltransferase activity 4/970 69/18639 0.0579710144927536 1.11393993724787 0.48641469626848 0.858159342259962 GO:0042826 histone deacetylase binding 7/970 127/18639 0.0551181102362205 1.0591200584463 0.493449575592737 0.858159342259962 GO:1901981 phosphatidylinositol phosphate binding 10/970 185/18639 0.0540540540540541 1.03867372527166 0.497253805378129 0.858159342259962 GO:0016782 transferase activity, transferring sulphur-containing groups 4/970 70/18639 0.0571428571428571 1.0980265095729 0.49772927766145 0.858159342259962 GO:0005021 vascular endothelial growth factor receptor activity 3/970 51/18639 0.0588235294117647 1.13032140691328 0.499610701278767 0.858159342259962 GO:0002161 aminoacyl-tRNA editing activity 1/970 13/18639 0.0769230769230769 1.47811260904044 0.500929508918019 0.858159342259962 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/970 13/18639 0.0769230769230769 1.47811260904044 0.500929508918019 0.858159342259962 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/970 13/18639 0.0769230769230769 1.47811260904044 0.500929508918019 0.858159342259962 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/970 13/18639 0.0769230769230769 1.47811260904044 0.500929508918019 0.858159342259962 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/970 13/18639 0.0769230769230769 1.47811260904044 0.500929508918019 0.858159342259962 GO:0017154 semaphorin receptor activity 1/970 13/18639 0.0769230769230769 1.47811260904044 0.500929508918019 0.858159342259962 GO:0019104 DNA N-glycosylase activity 1/970 13/18639 0.0769230769230769 1.47811260904044 0.500929508918019 0.858159342259962 GO:0035673 oligopeptide transmembrane transporter activity 1/970 13/18639 0.0769230769230769 1.47811260904044 0.500929508918019 0.858159342259962 GO:0043560 insulin receptor substrate binding 1/970 13/18639 0.0769230769230769 1.47811260904044 0.500929508918019 0.858159342259962 GO:0061459 L-arginine transmembrane transporter activity 1/970 13/18639 0.0769230769230769 1.47811260904044 0.500929508918019 0.858159342259962 GO:0070123 transforming growth factor beta receptor activity, type III 1/970 13/18639 0.0769230769230769 1.47811260904044 0.500929508918019 0.858159342259962 GO:0097157 pre-mRNA intronic binding 1/970 13/18639 0.0769230769230769 1.47811260904044 0.500929508918019 0.858159342259962 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/970 13/18639 0.0769230769230769 1.47811260904044 0.500929508918019 0.858159342259962 GO:0015106 bicarbonate transmembrane transporter activity 2/970 32/18639 0.0625 1.20096649484536 0.501680604077829 0.858159342259962 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/970 32/18639 0.0625 1.20096649484536 0.501680604077829 0.858159342259962 GO:0043425 bHLH transcription factor binding 2/970 32/18639 0.0625 1.20096649484536 0.501680604077829 0.858159342259962 GO:0047498 calcium-dependent phospholipase A2 activity 2/970 32/18639 0.0625 1.20096649484536 0.501680604077829 0.858159342259962 GO:0031406 carboxylic acid binding 10/970 187/18639 0.053475935828877 1.02756491537571 0.511050851572474 0.861804137095922 GO:0016247 channel regulator activity 9/970 168/18639 0.0535714285714286 1.02939985272459 0.513151144507894 0.861804137095922 GO:0043177 organic acid binding 10/970 189/18639 0.0529100529100529 1.0166912125675 0.524735141268199 0.861804137095922 GO:0005246 calcium channel regulator activity 3/970 53/18639 0.0566037735849057 1.08766776891655 0.525662678433867 0.861804137095922 GO:0005544 calcium-dependent phospholipid binding 3/970 53/18639 0.0566037735849057 1.08766776891655 0.525662678433867 0.861804137095922 GO:0008146 sulfotransferase activity 3/970 53/18639 0.0566037735849057 1.08766776891655 0.525662678433867 0.861804137095922 GO:0017046 peptide hormone binding 3/970 53/18639 0.0566037735849057 1.08766776891655 0.525662678433867 0.861804137095922 GO:0052689 carboxylic ester hydrolase activity 5/970 92/18639 0.0543478260869565 1.04431869116988 0.525707329744614 0.861804137095922 GO:0031072 heat shock protein binding 7/970 131/18639 0.0534351145038168 1.02678051467695 0.526510188146051 0.861804137095922 GO:0004065 arylsulfatase activity 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0004705 JUN kinase activity 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0005313 L-glutamate transmembrane transporter activity 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0005347 ATP transmembrane transporter activity 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0005545 1-phosphatidylinositol binding 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0008174 mRNA methyltransferase activity 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0008474 palmitoyl-(protein) hydrolase activity 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0019992 diacylglycerol binding 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0030983 mismatched DNA binding 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0031404 chloride ion binding 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0046030 inositol trisphosphate phosphatase activity 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0071933 Arp2/3 complex binding 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0098599 palmitoyl hydrolase activity 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0098821 BMP receptor activity 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0098847 sequence-specific single stranded DNA binding 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:1901612 cardiolipin binding 1/970 14/18639 0.0714285714285714 1.37253313696613 0.526919972589742 0.861804137095922 GO:0141108 transporter regulator activity 9/970 170/18639 0.0529411764705882 1.01728926622195 0.527568312062522 0.861804137095922 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 12/970 229/18639 0.0524017467248908 1.00692387340746 0.532398724268341 0.864738096288831 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 2/970 34/18639 0.0588235294117647 1.13032140691328 0.534405795890019 0.864738096288831 GO:0030332 cyclin binding 2/970 34/18639 0.0588235294117647 1.13032140691328 0.534405795890019 0.864738096288831 GO:0051427 hormone receptor binding 2/970 34/18639 0.0588235294117647 1.13032140691328 0.534405795890019 0.864738096288831 GO:0090482 vitamin transmembrane transporter activity 2/970 34/18639 0.0588235294117647 1.13032140691328 0.534405795890019 0.864738096288831 GO:0017069 snRNA binding 3/970 54/18639 0.0555555555555556 1.06752577319588 0.538404036604034 0.864738096288831 GO:0005085 guanyl-nucleotide exchange factor activity 12/970 230/18639 0.0521739130434783 1.00254594352308 0.538565652723552 0.864738096288831 GO:0003678 DNA helicase activity 4/970 74/18639 0.0540540540540541 1.03867372527166 0.541846278775436 0.864738096288831 GO:0004623 phospholipase A2 activity 2/970 35/18639 0.0571428571428571 1.0980265095729 0.550206065511204 0.864738096288831 GO:0005154 epidermal growth factor receptor binding 2/970 35/18639 0.0571428571428571 1.0980265095729 0.550206065511204 0.864738096288831 GO:0016229 steroid dehydrogenase activity 2/970 35/18639 0.0571428571428571 1.0980265095729 0.550206065511204 0.864738096288831 GO:0043015 gamma-tubulin binding 2/970 35/18639 0.0571428571428571 1.0980265095729 0.550206065511204 0.864738096288831 GO:0140566 histone reader activity 2/970 35/18639 0.0571428571428571 1.0980265095729 0.550206065511204 0.864738096288831 GO:0004559 alpha-mannosidase activity 1/970 15/18639 0.0666666666666667 1.28103092783505 0.551558234419967 0.864738096288831 GO:0005041 low-density lipoprotein particle receptor activity 1/970 15/18639 0.0666666666666667 1.28103092783505 0.551558234419967 0.864738096288831 GO:0008242 omega peptidase activity 1/970 15/18639 0.0666666666666667 1.28103092783505 0.551558234419967 0.864738096288831 GO:0010181 FMN binding 1/970 15/18639 0.0666666666666667 1.28103092783505 0.551558234419967 0.864738096288831 GO:0015116 sulfate transmembrane transporter activity 1/970 15/18639 0.0666666666666667 1.28103092783505 0.551558234419967 0.864738096288831 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/970 15/18639 0.0666666666666667 1.28103092783505 0.551558234419967 0.864738096288831 GO:0015929 hexosaminidase activity 1/970 15/18639 0.0666666666666667 1.28103092783505 0.551558234419967 0.864738096288831 GO:0017081 chloride channel regulator activity 1/970 15/18639 0.0666666666666667 1.28103092783505 0.551558234419967 0.864738096288831 GO:0050700 CARD domain binding 1/970 15/18639 0.0666666666666667 1.28103092783505 0.551558234419967 0.864738096288831 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/970 15/18639 0.0666666666666667 1.28103092783505 0.551558234419967 0.864738096288831 GO:0061578 K63-linked deubiquitinase activity 1/970 15/18639 0.0666666666666667 1.28103092783505 0.551558234419967 0.864738096288831 GO:0140776 protein-containing complex destabilizing activity 1/970 15/18639 0.0666666666666667 1.28103092783505 0.551558234419967 0.864738096288831 GO:0141050 histone H3K deacetylase activity 1/970 15/18639 0.0666666666666667 1.28103092783505 0.551558234419967 0.864738096288831 GO:0141051 histone H4K deacetylase activity 1/970 15/18639 0.0666666666666667 1.28103092783505 0.551558234419967 0.864738096288831 GO:0035401 histone H3Y41 kinase activity 6/970 115/18639 0.0521739130434783 1.00254594352308 0.556597576644611 0.870045543283998 GO:0140801 histone H2AXY142 kinase activity 6/970 115/18639 0.0521739130434783 1.00254594352308 0.556597576644611 0.870045543283998 GO:0000993 RNA polymerase II complex binding 2/970 36/18639 0.0555555555555556 1.06752577319588 0.565624752236343 0.875267922357277 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/970 36/18639 0.0555555555555556 1.06752577319588 0.565624752236343 0.875267922357277 GO:0045505 dynein intermediate chain binding 2/970 36/18639 0.0555555555555556 1.06752577319588 0.565624752236343 0.875267922357277 GO:0003688 DNA replication origin binding 1/970 16/18639 0.0625 1.20096649484536 0.574914576377261 0.875267922357277 GO:0004707 MAP kinase activity 1/970 16/18639 0.0625 1.20096649484536 0.574914576377261 0.875267922357277 GO:0008296 3'-5'-DNA exonuclease activity 1/970 16/18639 0.0625 1.20096649484536 0.574914576377261 0.875267922357277 GO:0015923 mannosidase activity 1/970 16/18639 0.0625 1.20096649484536 0.574914576377261 0.875267922357277 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/970 16/18639 0.0625 1.20096649484536 0.574914576377261 0.875267922357277 GO:0016722 oxidoreductase activity, acting on metal ions 1/970 16/18639 0.0625 1.20096649484536 0.574914576377261 0.875267922357277 GO:0017070 U6 snRNA binding 1/970 16/18639 0.0625 1.20096649484536 0.574914576377261 0.875267922357277 GO:0022841 potassium ion leak channel activity 1/970 16/18639 0.0625 1.20096649484536 0.574914576377261 0.875267922357277 GO:0022858 alanine transmembrane transporter activity 1/970 16/18639 0.0625 1.20096649484536 0.574914576377261 0.875267922357277 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/970 16/18639 0.0625 1.20096649484536 0.574914576377261 0.875267922357277 GO:0043023 ribosomal large subunit binding 1/970 16/18639 0.0625 1.20096649484536 0.574914576377261 0.875267922357277 GO:0055102 lipase inhibitor activity 1/970 16/18639 0.0625 1.20096649484536 0.574914576377261 0.875267922357277 GO:0070411 I-SMAD binding 1/970 16/18639 0.0625 1.20096649484536 0.574914576377261 0.875267922357277 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/970 16/18639 0.0625 1.20096649484536 0.574914576377261 0.875267922357277 GO:0140328 floppase activity 1/970 16/18639 0.0625 1.20096649484536 0.574914576377261 0.875267922357277 GO:0022829 wide pore channel activity 2/970 37/18639 0.0540540540540541 1.03867372527166 0.580658744379425 0.881461759144525 GO:0023023 MHC protein complex binding 2/970 37/18639 0.0540540540540541 1.03867372527166 0.580658744379425 0.881461759144525 GO:0042162 telomeric DNA binding 2/970 38/18639 0.0526315789473684 1.01134020618557 0.595306285930649 0.882268166841021 GO:0042887 amide transmembrane transporter activity 2/970 38/18639 0.0526315789473684 1.01134020618557 0.595306285930649 0.882268166841021 GO:0004549 tRNA-specific ribonuclease activity 1/970 17/18639 0.0588235294117647 1.13032140691328 0.597055631036234 0.882268166841021 GO:0004550 nucleoside diphosphate kinase activity 1/970 17/18639 0.0588235294117647 1.13032140691328 0.597055631036234 0.882268166841021 GO:0004659 prenyltransferase activity 1/970 17/18639 0.0588235294117647 1.13032140691328 0.597055631036234 0.882268166841021 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/970 17/18639 0.0588235294117647 1.13032140691328 0.597055631036234 0.882268166841021 GO:0005092 GDP-dissociation inhibitor activity 1/970 17/18639 0.0588235294117647 1.13032140691328 0.597055631036234 0.882268166841021 GO:0008484 sulfuric ester hydrolase activity 1/970 17/18639 0.0588235294117647 1.13032140691328 0.597055631036234 0.882268166841021 GO:0015278 intracellularly gated calcium channel activity 1/970 17/18639 0.0588235294117647 1.13032140691328 0.597055631036234 0.882268166841021 GO:0016018 cyclosporin A binding 1/970 17/18639 0.0588235294117647 1.13032140691328 0.597055631036234 0.882268166841021 GO:0017110 nucleoside diphosphate phosphatase activity 1/970 17/18639 0.0588235294117647 1.13032140691328 0.597055631036234 0.882268166841021 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/970 17/18639 0.0588235294117647 1.13032140691328 0.597055631036234 0.882268166841021 GO:0030548 acetylcholine receptor regulator activity 1/970 17/18639 0.0588235294117647 1.13032140691328 0.597055631036234 0.882268166841021 GO:0032183 SUMO binding 1/970 17/18639 0.0588235294117647 1.13032140691328 0.597055631036234 0.882268166841021 GO:0045236 CXCR chemokine receptor binding 1/970 17/18639 0.0588235294117647 1.13032140691328 0.597055631036234 0.882268166841021 GO:0046965 nuclear retinoid X receptor binding 1/970 17/18639 0.0588235294117647 1.13032140691328 0.597055631036234 0.882268166841021 GO:0070402 NADPH binding 1/970 17/18639 0.0588235294117647 1.13032140691328 0.597055631036234 0.882268166841021 GO:0070403 NAD+ binding 1/970 17/18639 0.0588235294117647 1.13032140691328 0.597055631036234 0.882268166841021 GO:0099106 ion channel regulator activity 8/970 160/18639 0.05 0.960773195876289 0.597124462728904 0.882268166841021 GO:0001786 phosphatidylserine binding 3/970 59/18639 0.0508474576271186 0.977057487331819 0.599033444229459 0.882609500461332 GO:0045309 protein phosphorylated amino acid binding 3/970 59/18639 0.0508474576271186 0.977057487331819 0.599033444229459 0.882609500461332 GO:0004540 RNA nuclease activity 6/970 121/18639 0.0495867768595041 0.952832921530204 0.606691330850066 0.887717241798041 GO:0033192 calmodulin-dependent protein phosphatase activity 4/970 81/18639 0.0493827160493827 0.948911798396334 0.613912826454053 0.887717241798041 GO:0140791 histone H2AXS140 phosphatase activity 4/970 81/18639 0.0493827160493827 0.948911798396334 0.613912826454053 0.887717241798041 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 4/970 81/18639 0.0493827160493827 0.948911798396334 0.613912826454053 0.887717241798041 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 4/970 81/18639 0.0493827160493827 0.948911798396334 0.613912826454053 0.887717241798041 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 4/970 81/18639 0.0493827160493827 0.948911798396334 0.613912826454053 0.887717241798041 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 4/970 81/18639 0.0493827160493827 0.948911798396334 0.613912826454053 0.887717241798041 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 4/970 81/18639 0.0493827160493827 0.948911798396334 0.613912826454053 0.887717241798041 GO:1990439 MAP kinase serine/threonine phosphatase activity 4/970 81/18639 0.0493827160493827 0.948911798396334 0.613912826454053 0.887717241798041 GO:0008308 voltage-gated monoatomic anion channel activity 1/970 18/18639 0.0555555555555556 1.06752577319588 0.618044570886672 0.887717241798041 GO:0015172 acidic amino acid transmembrane transporter activity 1/970 18/18639 0.0555555555555556 1.06752577319588 0.618044570886672 0.887717241798041 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/970 18/18639 0.0555555555555556 1.06752577319588 0.618044570886672 0.887717241798041 GO:0017128 phospholipid scramblase activity 1/970 18/18639 0.0555555555555556 1.06752577319588 0.618044570886672 0.887717241798041 GO:0030228 lipoprotein particle receptor activity 1/970 18/18639 0.0555555555555556 1.06752577319588 0.618044570886672 0.887717241798041 GO:0070064 proline-rich region binding 1/970 18/18639 0.0555555555555556 1.06752577319588 0.618044570886672 0.887717241798041 GO:0099602 neurotransmitter receptor regulator activity 1/970 18/18639 0.0555555555555556 1.06752577319588 0.618044570886672 0.887717241798041 GO:0003714 transcription corepressor activity 10/970 204/18639 0.0490196078431373 0.941934505761067 0.62250342448481 0.887717241798041 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/970 40/18639 0.05 0.960773195876289 0.623440987241551 0.887717241798041 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 4/970 82/18639 0.0487804878048781 0.93733970329394 0.62361571649887 0.887717241798041 GO:0033549 MAP kinase phosphatase activity 4/970 82/18639 0.0487804878048781 0.93733970329394 0.62361571649887 0.887717241798041 GO:0004722 protein serine/threonine phosphatase activity 5/970 103/18639 0.0485436893203883 0.932789510559504 0.626791223489473 0.887717241798041 GO:0005253 monoatomic anion channel activity 5/970 103/18639 0.0485436893203883 0.932789510559504 0.626791223489473 0.887717241798041 GO:0015179 L-amino acid transmembrane transporter activity 3/970 62/18639 0.0483870967741935 0.929780512138344 0.632806244687853 0.887717241798041 GO:0001540 amyloid-beta binding 4/970 83/18639 0.0481927710843374 0.926046453856664 0.633162798039513 0.887717241798041 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 4/970 83/18639 0.0481927710843374 0.926046453856664 0.633162798039513 0.887717241798041 GO:0005254 chloride channel activity 4/970 83/18639 0.0481927710843374 0.926046453856664 0.633162798039513 0.887717241798041 GO:0008194 UDP-glycosyltransferase activity 7/970 145/18639 0.0482758620689655 0.927643085673658 0.634531858832314 0.887717241798041 GO:0004812 aminoacyl-tRNA ligase activity 2/970 41/18639 0.0487804878048781 0.93733970329394 0.636930271438729 0.887717241798041 GO:0016875 ligase activity, forming carbon-oxygen bonds 2/970 41/18639 0.0487804878048781 0.93733970329394 0.636930271438729 0.887717241798041 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/970 19/18639 0.0526315789473684 1.01134020618557 0.637941287832052 0.887717241798041 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/970 19/18639 0.0526315789473684 1.01134020618557 0.637941287832052 0.887717241798041 GO:0005229 intracellularly calcium-gated chloride channel activity 1/970 19/18639 0.0526315789473684 1.01134020618557 0.637941287832052 0.887717241798041 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/970 19/18639 0.0526315789473684 1.01134020618557 0.637941287832052 0.887717241798041 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/970 19/18639 0.0526315789473684 1.01134020618557 0.637941287832052 0.887717241798041 GO:0022840 leak channel activity 1/970 19/18639 0.0526315789473684 1.01134020618557 0.637941287832052 0.887717241798041 GO:0022842 narrow pore channel activity 1/970 19/18639 0.0526315789473684 1.01134020618557 0.637941287832052 0.887717241798041 GO:0034987 immunoglobulin receptor binding 1/970 19/18639 0.0526315789473684 1.01134020618557 0.637941287832052 0.887717241798041 GO:0042577 lipid phosphatase activity 1/970 19/18639 0.0526315789473684 1.01134020618557 0.637941287832052 0.887717241798041 GO:0042800 histone H3K4 methyltransferase activity 1/970 19/18639 0.0526315789473684 1.01134020618557 0.637941287832052 0.887717241798041 GO:0046527 glucosyltransferase activity 1/970 19/18639 0.0526315789473684 1.01134020618557 0.637941287832052 0.887717241798041 GO:0050145 nucleoside monophosphate kinase activity 1/970 19/18639 0.0526315789473684 1.01134020618557 0.637941287832052 0.887717241798041 GO:0141147 intracellularly calcium-gated channel activity 1/970 19/18639 0.0526315789473684 1.01134020618557 0.637941287832052 0.887717241798041 GO:0017018 myosin phosphatase activity 4/970 84/18639 0.0476190476190476 0.915022091310751 0.642552249320023 0.892952399319239 GO:0042277 peptide binding 12/970 249/18639 0.0481927710843374 0.926046453856664 0.649302705605112 0.900973739047694 GO:0043175 RNA polymerase core enzyme binding 2/970 42/18639 0.0476190476190476 0.915022091310751 0.650037136822434 0.900973739047694 GO:0015095 magnesium ion transmembrane transporter activity 1/970 20/18639 0.05 0.960773195876289 0.656802563385377 0.905578370486785 GO:0016408 C-acyltransferase activity 1/970 20/18639 0.05 0.960773195876289 0.656802563385377 0.905578370486785 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/970 20/18639 0.05 0.960773195876289 0.656802563385377 0.905578370486785 GO:0061608 nuclear import signal receptor activity 1/970 20/18639 0.05 0.960773195876289 0.656802563385377 0.905578370486785 GO:0004674 protein serine/threonine kinase activity 21/970 433/18639 0.0484988452655889 0.931927811242589 0.662672905403682 0.909033352658456 GO:0008509 monoatomic anion transmembrane transporter activity 7/970 149/18639 0.0469798657718121 0.902739915588459 0.662683191822697 0.909033352658456 GO:0008375 acetylglucosaminyltransferase activity 2/970 43/18639 0.0465116279069767 0.893742507791896 0.662764811301365 0.909033352658456 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/970 43/18639 0.0465116279069767 0.893742507791896 0.662764811301365 0.909033352658456 GO:0005496 steroid binding 5/970 108/18639 0.0462962962962963 0.889604810996564 0.668180411077224 0.915267958923489 GO:0008081 phosphoric diester hydrolase activity 4/970 87/18639 0.0459770114942529 0.883469605403484 0.669760681300721 0.916239579620752 GO:0015174 basic amino acid transmembrane transporter activity 1/970 21/18639 0.0476190476190476 0.915022091310751 0.674682230043961 0.919299698820056 GO:0001223 transcription coactivator binding 2/970 44/18639 0.0454545454545455 0.873430178069353 0.675117222170226 0.919299698820056 GO:0019205 nucleobase-containing compound kinase activity 2/970 44/18639 0.0454545454545455 0.873430178069353 0.675117222170226 0.919299698820056 GO:0004620 phospholipase activity 5/970 109/18639 0.0458715596330275 0.881443298969072 0.676086354377297 0.919299698820056 GO:0004197 cysteine-type endopeptidase activity 4/970 88/18639 0.0454545454545455 0.873430178069353 0.678506750836463 0.919299698820056 GO:0140030 modification-dependent protein binding 8/970 173/18639 0.046242774566474 0.888576366128359 0.68384406632765 0.919299698820056 GO:0042605 peptide antigen binding 2/970 45/18639 0.0444444444444444 0.854020618556701 0.687098914724435 0.919299698820056 GO:0140303 intramembrane lipid transporter activity 2/970 45/18639 0.0444444444444444 0.854020618556701 0.687098914724435 0.919299698820056 GO:0004407 histone deacetylase activity 1/970 22/18639 0.0454545454545455 0.873430178069353 0.691631324299916 0.919299698820056 GO:0005243 gap junction channel activity 1/970 22/18639 0.0454545454545455 0.873430178069353 0.691631324299916 0.919299698820056 GO:0008649 rRNA methyltransferase activity 1/970 22/18639 0.0454545454545455 0.873430178069353 0.691631324299916 0.919299698820056 GO:0031683 G-protein beta/gamma-subunit complex binding 1/970 22/18639 0.0454545454545455 0.873430178069353 0.691631324299916 0.919299698820056 GO:0033558 protein lysine deacetylase activity 1/970 22/18639 0.0454545454545455 0.873430178069353 0.691631324299916 0.919299698820056 GO:0033691 sialic acid binding 1/970 22/18639 0.0454545454545455 0.873430178069353 0.691631324299916 0.919299698820056 GO:0050321 tau-protein kinase activity 1/970 22/18639 0.0454545454545455 0.873430178069353 0.691631324299916 0.919299698820056 GO:0070034 telomerase RNA binding 1/970 22/18639 0.0454545454545455 0.873430178069353 0.691631324299916 0.919299698820056 GO:0140784 metal ion sensor activity 1/970 22/18639 0.0454545454545455 0.873430178069353 0.691631324299916 0.919299698820056 GO:0001217 DNA-binding transcription repressor activity 13/970 278/18639 0.0467625899280576 0.898564859452644 0.693704507405228 0.919299698820056 GO:0016758 hexosyltransferase activity 9/970 197/18639 0.0456852791878173 0.877863833795594 0.702563527708637 0.919299698820056 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 4/970 91/18639 0.043956043956044 0.84463577659454 0.703766914923066 0.919299698820056 GO:0072341 modified amino acid binding 4/970 91/18639 0.043956043956044 0.84463577659454 0.703766914923066 0.919299698820056 GO:0000295 adenine nucleotide transmembrane transporter activity 1/970 23/18639 0.0434782608695652 0.835454952935903 0.707698231719429 0.919299698820056 GO:0005283 amino acid:sodium symporter activity 1/970 23/18639 0.0434782608695652 0.835454952935903 0.707698231719429 0.919299698820056 GO:0016493 C-C chemokine receptor activity 1/970 23/18639 0.0434782608695652 0.835454952935903 0.707698231719429 0.919299698820056 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/970 23/18639 0.0434782608695652 0.835454952935903 0.707698231719429 0.919299698820056 GO:0070577 lysine-acetylated histone binding 1/970 23/18639 0.0434782608695652 0.835454952935903 0.707698231719429 0.919299698820056 GO:0140102 catalytic activity, acting on a rRNA 1/970 23/18639 0.0434782608695652 0.835454952935903 0.707698231719429 0.919299698820056 GO:0061749 forked DNA-dependent helicase activity 2/970 47/18639 0.0425531914893617 0.817679315639395 0.709970973234511 0.919299698820056 GO:1990518 single-stranded 3'-5' DNA helicase activity 2/970 47/18639 0.0425531914893617 0.817679315639395 0.709970973234511 0.919299698820056 GO:0140789 histone phosphatase activity 6/970 136/18639 0.0441176470588235 0.847741055184961 0.716978407119766 0.919299698820056 GO:0101005 deubiquitinase activity 5/970 115/18639 0.0434782608695652 0.835454952935903 0.720853190171221 0.919299698820056 GO:0009378 four-way junction helicase activity 2/970 48/18639 0.0416666666666667 0.800644329896907 0.720872876445742 0.919299698820056 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/970 48/18639 0.0416666666666667 0.800644329896907 0.720872876445742 0.919299698820056 GO:0036121 double-stranded DNA helicase activity 2/970 48/18639 0.0416666666666667 0.800644329896907 0.720872876445742 0.919299698820056 GO:0038187 pattern recognition receptor activity 2/970 48/18639 0.0416666666666667 0.800644329896907 0.720872876445742 0.919299698820056 GO:0043138 3'-5' DNA helicase activity 2/970 48/18639 0.0416666666666667 0.800644329896907 0.720872876445742 0.919299698820056 GO:0140299 molecular sensor activity 3/970 71/18639 0.0422535211267606 0.811921010599681 0.721918487534672 0.919299698820056 GO:0004622 lysophospholipase activity 1/970 24/18639 0.0416666666666667 0.800644329896907 0.72292882450156 0.919299698820056 GO:0005315 phosphate transmembrane transporter activity 1/970 24/18639 0.0416666666666667 0.800644329896907 0.72292882450156 0.919299698820056 GO:0015149 hexose transmembrane transporter activity 1/970 24/18639 0.0416666666666667 0.800644329896907 0.72292882450156 0.919299698820056 GO:0019957 C-C chemokine binding 1/970 24/18639 0.0416666666666667 0.800644329896907 0.72292882450156 0.919299698820056 GO:0030552 cAMP binding 1/970 24/18639 0.0416666666666667 0.800644329896907 0.72292882450156 0.919299698820056 GO:0035035 histone acetyltransferase binding 1/970 24/18639 0.0416666666666667 0.800644329896907 0.72292882450156 0.919299698820056 GO:0055056 D-glucose transmembrane transporter activity 1/970 24/18639 0.0416666666666667 0.800644329896907 0.72292882450156 0.919299698820056 GO:0070840 dynein complex binding 1/970 24/18639 0.0416666666666667 0.800644329896907 0.72292882450156 0.919299698820056 GO:0140033 acetylation-dependent protein binding 1/970 24/18639 0.0416666666666667 0.800644329896907 0.72292882450156 0.919299698820056 GO:0001222 transcription corepressor binding 2/970 49/18639 0.0408163265306122 0.784304649694929 0.731427015011982 0.919299698820056 GO:0005004 GPI-linked ephrin receptor activity 2/970 49/18639 0.0408163265306122 0.784304649694929 0.731427015011982 0.919299698820056 GO:0005008 hepatocyte growth factor receptor activity 2/970 49/18639 0.0408163265306122 0.784304649694929 0.731427015011982 0.919299698820056 GO:0005009 insulin receptor activity 2/970 49/18639 0.0408163265306122 0.784304649694929 0.731427015011982 0.919299698820056 GO:0005011 macrophage colony-stimulating factor receptor activity 2/970 49/18639 0.0408163265306122 0.784304649694929 0.731427015011982 0.919299698820056 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/970 49/18639 0.0408163265306122 0.784304649694929 0.731427015011982 0.919299698820056 GO:0005020 stem cell factor receptor activity 2/970 49/18639 0.0408163265306122 0.784304649694929 0.731427015011982 0.919299698820056 GO:0008288 boss receptor activity 2/970 49/18639 0.0408163265306122 0.784304649694929 0.731427015011982 0.919299698820056 GO:0016763 pentosyltransferase activity 2/970 49/18639 0.0408163265306122 0.784304649694929 0.731427015011982 0.919299698820056 GO:0035254 glutamate receptor binding 2/970 49/18639 0.0408163265306122 0.784304649694929 0.731427015011982 0.919299698820056 GO:0036332 placental growth factor receptor activity 2/970 49/18639 0.0408163265306122 0.784304649694929 0.731427015011982 0.919299698820056 GO:0038062 protein tyrosine kinase collagen receptor activity 2/970 49/18639 0.0408163265306122 0.784304649694929 0.731427015011982 0.919299698820056 GO:0060175 brain-derived neurotrophic factor receptor activity 2/970 49/18639 0.0408163265306122 0.784304649694929 0.731427015011982 0.919299698820056 GO:0060590 ATPase regulator activity 2/970 49/18639 0.0408163265306122 0.784304649694929 0.731427015011982 0.919299698820056 GO:0008276 protein methyltransferase activity 4/970 95/18639 0.0421052631578947 0.809072164948454 0.735165691400552 0.919299698820056 GO:0004709 MAP kinase kinase kinase activity 1/970 25/18639 0.04 0.768618556701031 0.737366591905992 0.919299698820056 GO:0005251 delayed rectifier potassium channel activity 1/970 25/18639 0.04 0.768618556701031 0.737366591905992 0.919299698820056 GO:0008139 nuclear localization sequence binding 1/970 25/18639 0.04 0.768618556701031 0.737366591905992 0.919299698820056 GO:0015271 outward rectifier potassium channel activity 1/970 25/18639 0.04 0.768618556701031 0.737366591905992 0.919299698820056 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/970 25/18639 0.04 0.768618556701031 0.737366591905992 0.919299698820056 GO:0042974 nuclear retinoic acid receptor binding 1/970 25/18639 0.04 0.768618556701031 0.737366591905992 0.919299698820056 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/970 25/18639 0.04 0.768618556701031 0.737366591905992 0.919299698820056 GO:0120020 cholesterol transfer activity 1/970 25/18639 0.04 0.768618556701031 0.737366591905992 0.919299698820056 GO:0005006 epidermal growth factor receptor activity 2/970 50/18639 0.04 0.768618556701031 0.741640017590541 0.919299698820056 GO:0005017 platelet-derived growth factor receptor activity 2/970 50/18639 0.04 0.768618556701031 0.741640017590541 0.919299698820056 GO:0005019 platelet-derived growth factor beta-receptor activity 2/970 50/18639 0.04 0.768618556701031 0.741640017590541 0.919299698820056 GO:0015605 organophosphate ester transmembrane transporter activity 2/970 50/18639 0.04 0.768618556701031 0.741640017590541 0.919299698820056 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 12/970 268/18639 0.0447761194029851 0.860393906754885 0.744019100629329 0.919299698820056 GO:0042393 histone binding 11/970 247/18639 0.0445344129554656 0.855749405233941 0.74405438033997 0.919299698820056 GO:0003684 damaged DNA binding 3/970 74/18639 0.0405405405405405 0.779005293953748 0.747596005692357 0.919299698820056 GO:0001637 G protein-coupled chemoattractant receptor activity 1/970 26/18639 0.0384615384615385 0.739056304520222 0.751052763919056 0.919299698820056 GO:0004529 DNA exonuclease activity 1/970 26/18639 0.0384615384615385 0.739056304520222 0.751052763919056 0.919299698820056 GO:0004950 chemokine receptor activity 1/970 26/18639 0.0384615384615385 0.739056304520222 0.751052763919056 0.919299698820056 GO:0005112 Notch binding 1/970 26/18639 0.0384615384615385 0.739056304520222 0.751052763919056 0.919299698820056 GO:0008157 protein phosphatase 1 binding 1/970 26/18639 0.0384615384615385 0.739056304520222 0.751052763919056 0.919299698820056 GO:0015145 monosaccharide transmembrane transporter activity 1/970 26/18639 0.0384615384615385 0.739056304520222 0.751052763919056 0.919299698820056 GO:0015216 purine nucleotide transmembrane transporter activity 1/970 26/18639 0.0384615384615385 0.739056304520222 0.751052763919056 0.919299698820056 GO:0019865 immunoglobulin binding 1/970 26/18639 0.0384615384615385 0.739056304520222 0.751052763919056 0.919299698820056 GO:0030247 polysaccharide binding 1/970 26/18639 0.0384615384615385 0.739056304520222 0.751052763919056 0.919299698820056 GO:0030507 spectrin binding 1/970 26/18639 0.0384615384615385 0.739056304520222 0.751052763919056 0.919299698820056 GO:0034237 protein kinase A regulatory subunit binding 1/970 26/18639 0.0384615384615385 0.739056304520222 0.751052763919056 0.919299698820056 GO:0070412 R-SMAD binding 1/970 26/18639 0.0384615384615385 0.739056304520222 0.751052763919056 0.919299698820056 GO:0097602 cullin family protein binding 1/970 26/18639 0.0384615384615385 0.739056304520222 0.751052763919056 0.919299698820056 GO:0005010 insulin-like growth factor receptor activity 2/970 51/18639 0.0392156862745098 0.753547604608854 0.751518765195103 0.919299698820056 GO:0005030 neurotrophin receptor activity 2/970 51/18639 0.0392156862745098 0.753547604608854 0.751518765195103 0.919299698820056 GO:0032182 ubiquitin-like protein binding 5/970 120/18639 0.0416666666666667 0.800644329896907 0.754644018161534 0.921738305952604 GO:0008170 N-methyltransferase activity 4/970 98/18639 0.0408163265306122 0.784304649694929 0.757021674487687 0.921738305952604 GO:0003697 single-stranded DNA binding 5/970 121/18639 0.0413223140495868 0.794027434608503 0.761021289166338 0.921738305952604 GO:0015108 chloride transmembrane transporter activity 5/970 121/18639 0.0413223140495868 0.794027434608503 0.761021289166338 0.921738305952604 GO:0005080 protein kinase C binding 2/970 52/18639 0.0384615384615385 0.739056304520222 0.761070347046202 0.921738305952604 GO:0015103 inorganic anion transmembrane transporter activity 7/970 165/18639 0.0424242424242424 0.815201499531396 0.761318097335817 0.921738305952604 GO:0008234 cysteine-type peptidase activity 8/970 187/18639 0.0427807486631016 0.822051932300568 0.763075494089198 0.921738305952604 GO:0005104 fibroblast growth factor receptor binding 1/970 27/18639 0.037037037037037 0.711683848797251 0.764026428508242 0.921738305952604 GO:0005385 zinc ion transmembrane transporter activity 1/970 27/18639 0.037037037037037 0.711683848797251 0.764026428508242 0.921738305952604 GO:0008395 steroid hydroxylase activity 1/970 27/18639 0.037037037037037 0.711683848797251 0.764026428508242 0.921738305952604 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/970 27/18639 0.037037037037037 0.711683848797251 0.764026428508242 0.921738305952604 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/970 27/18639 0.037037037037037 0.711683848797251 0.764026428508242 0.921738305952604 GO:0005003 ephrin receptor activity 2/970 53/18639 0.0377358490566038 0.725111845944369 0.770302020325117 0.923556271078869 GO:0005005 transmembrane-ephrin receptor activity 2/970 53/18639 0.0377358490566038 0.725111845944369 0.770302020325117 0.923556271078869 GO:0034212 protein N-acetyltransferase activity 2/970 53/18639 0.0377358490566038 0.725111845944369 0.770302020325117 0.923556271078869 GO:0038064 collagen receptor activity 2/970 53/18639 0.0377358490566038 0.725111845944369 0.770302020325117 0.923556271078869 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/970 53/18639 0.0377358490566038 0.725111845944369 0.770302020325117 0.923556271078869 GO:0043130 ubiquitin binding 4/970 100/18639 0.04 0.768618556701031 0.770800766166585 0.923556271078869 GO:0005126 cytokine receptor binding 12/970 275/18639 0.0436363636363636 0.838492970946579 0.774241937194047 0.924907728451536 GO:0050698 proteoglycan sulfotransferase activity 1/970 28/18639 0.0357142857142857 0.686266568483063 0.77632464279725 0.924907728451536 GO:0051119 sugar transmembrane transporter activity 1/970 28/18639 0.0357142857142857 0.686266568483063 0.77632464279725 0.924907728451536 GO:0051959 dynein light intermediate chain binding 1/970 28/18639 0.0357142857142857 0.686266568483063 0.77632464279725 0.924907728451536 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/970 28/18639 0.0357142857142857 0.686266568483063 0.77632464279725 0.924907728451536 GO:0015293 symporter activity 6/970 146/18639 0.0410958904109589 0.789676599350374 0.777512374934532 0.92527490772752 GO:0050661 NADP binding 2/970 54/18639 0.037037037037037 0.711683848797251 0.779221173545159 0.926260649231082 GO:0015171 amino acid transmembrane transporter activity 4/970 102/18639 0.0392156862745098 0.753547604608854 0.783959050217017 0.930840768429234 GO:0004629 phospholipase C activity 1/970 29/18639 0.0344827586206897 0.662602204052613 0.787982538476507 0.931413067952007 GO:0005416 amino acid:monoatomic cation symporter activity 1/970 29/18639 0.0344827586206897 0.662602204052613 0.787982538476507 0.931413067952007 GO:0035250 UDP-galactosyltransferase activity 1/970 29/18639 0.0344827586206897 0.662602204052613 0.787982538476507 0.931413067952007 GO:0099604 ligand-gated calcium channel activity 1/970 29/18639 0.0344827586206897 0.662602204052613 0.787982538476507 0.931413067952007 GO:0004519 endonuclease activity 5/970 127/18639 0.0393700787401575 0.756514327461645 0.796674713939243 0.938150847855615 GO:0019783 ubiquitin-like protein peptidase activity 5/970 127/18639 0.0393700787401575 0.756514327461645 0.796674713939243 0.938150847855615 GO:0015215 nucleotide transmembrane transporter activity 1/970 30/18639 0.0333333333333333 0.640515463917526 0.799033421747748 0.938150847855615 GO:0032452 histone demethylase activity 1/970 30/18639 0.0333333333333333 0.640515463917526 0.799033421747748 0.938150847855615 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/970 30/18639 0.0333333333333333 0.640515463917526 0.799033421747748 0.938150847855615 GO:0051721 protein phosphatase 2A binding 1/970 30/18639 0.0333333333333333 0.640515463917526 0.799033421747748 0.938150847855615 GO:0030971 receptor tyrosine kinase binding 3/970 81/18639 0.037037037037037 0.711683848797251 0.800124029609911 0.938384034726451 GO:0031490 chromatin DNA binding 5/970 128/18639 0.0390625 0.75060405927835 0.802190641950915 0.939760083889046 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/970 57/18639 0.0350877192982456 0.674226804123711 0.804178690602234 0.941041137389934 GO:0140457 protein demethylase activity 1/970 31/18639 0.032258064516129 0.619853674758896 0.809508868085793 0.944407199179958 GO:0004721 phosphoprotein phosphatase activity 7/970 175/18639 0.04 0.768618556701031 0.811351384259463 0.944407199179958 GO:0008408 3'-5' exonuclease activity 2/970 58/18639 0.0344827586206897 0.662602204052613 0.811923174147108 0.944407199179958 GO:0017116 single-stranded DNA helicase activity 2/970 58/18639 0.0344827586206897 0.662602204052613 0.811923174147108 0.944407199179958 GO:0016298 lipase activity 5/970 130/18639 0.0384615384615385 0.739056304520222 0.812867041484467 0.944407199179958 GO:0016798 hydrolase activity, acting on glycosyl bonds 5/970 130/18639 0.0384615384615385 0.739056304520222 0.812867041484467 0.944407199179958 GO:0030165 PDZ domain binding 3/970 83/18639 0.036144578313253 0.694534840392498 0.813339279902132 0.944407199179958 GO:0036002 pre-mRNA binding 2/970 59/18639 0.0338983050847458 0.651371658221213 0.819392989231937 0.946995442972534 GO:0008378 galactosyltransferase activity 1/970 32/18639 0.03125 0.60048324742268 0.81943881208605 0.946995442972534 GO:0120015 sterol transfer activity 1/970 32/18639 0.03125 0.60048324742268 0.81943881208605 0.946995442972534 GO:0004527 exonuclease activity 3/970 84/18639 0.0357142857142857 0.686266568483063 0.819664725479247 0.946995442972534 GO:0015291 secondary active transmembrane transporter activity 12/970 287/18639 0.0418118466898955 0.803434031394806 0.820069247669181 0.946995442972534 GO:0016757 glycosyltransferase activity 11/970 267/18639 0.0411985018726592 0.7916483261902 0.826234068643083 0.950874501145297 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/970 60/18639 0.0333333333333333 0.640515463917526 0.826595714272922 0.950874501145297 GO:0019239 deaminase activity 1/970 33/18639 0.0303030303030303 0.582286785379569 0.828851632652317 0.950874501145297 GO:0019956 chemokine binding 1/970 33/18639 0.0303030303030303 0.582286785379569 0.828851632652317 0.950874501145297 GO:0030296 protein tyrosine kinase activator activity 1/970 33/18639 0.0303030303030303 0.582286785379569 0.828851632652317 0.950874501145297 GO:0140311 protein sequestering activity 1/970 33/18639 0.0303030303030303 0.582286785379569 0.828851632652317 0.950874501145297 GO:0050660 flavin adenine dinucleotide binding 3/970 86/18639 0.0348837209302326 0.670306880843922 0.831768964892293 0.953181863907073 GO:0015026 coreceptor activity 2/970 61/18639 0.0327868852459016 0.630015210410681 0.833538883608273 0.954170735098916 GO:0015297 antiporter activity 5/970 135/18639 0.037037037037037 0.711683848797251 0.837545244741065 0.955898583429691 GO:0015020 glucuronosyltransferase activity 1/970 34/18639 0.0294117647058824 0.56516070345664 0.837774233766326 0.955898583429691 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/970 34/18639 0.0294117647058824 0.56516070345664 0.837774233766326 0.955898583429691 GO:0000175 3'-5'-RNA exonuclease activity 1/970 35/18639 0.0285714285714286 0.549013254786451 0.846232121067947 0.961726040191092 GO:0005343 organic acid:sodium symporter activity 1/970 35/18639 0.0285714285714286 0.549013254786451 0.846232121067947 0.961726040191092 GO:0061631 ubiquitin conjugating enzyme activity 1/970 35/18639 0.0285714285714286 0.549013254786451 0.846232121067947 0.961726040191092 GO:0016791 phosphatase activity 11/970 273/18639 0.0402930402930403 0.774249461878328 0.846538320548432 0.961726040191092 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 3/970 89/18639 0.0337078651685393 0.647712266882891 0.848613038562144 0.962005298025189 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 3/970 89/18639 0.0337078651685393 0.647712266882891 0.848613038562144 0.962005298025189 GO:0004536 DNA nuclease activity 2/970 64/18639 0.03125 0.60048324742268 0.852885417422655 0.964238677183712 GO:0140793 histone H2AXY142 phosphatase activity 3/970 90/18639 0.0333333333333333 0.640515463917526 0.853892450379498 0.964238677183712 GO:0004190 aspartic-type endopeptidase activity 1/970 36/18639 0.0277777777777778 0.533762886597938 0.854249474463136 0.964238677183712 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/970 36/18639 0.0277777777777778 0.533762886597938 0.854249474463136 0.964238677183712 GO:0004518 nuclease activity 8/970 209/18639 0.0382775119617225 0.73552014995314 0.857049492687275 0.966362343308696 GO:0015294 solute:monoatomic cation symporter activity 4/970 116/18639 0.0344827586206897 0.662602204052613 0.859895893353397 0.966594217748044 GO:0019213 deacetylase activity 1/970 37/18639 0.027027027027027 0.519336862635832 0.861849216965462 0.966594217748044 GO:0030280 structural constituent of skin epidermis 1/970 37/18639 0.027027027027027 0.519336862635832 0.861849216965462 0.966594217748044 GO:0030551 cyclic nucleotide binding 1/970 37/18639 0.027027027027027 0.519336862635832 0.861849216965462 0.966594217748044 GO:0070001 aspartic-type peptidase activity 1/970 37/18639 0.027027027027027 0.519336862635832 0.861849216965462 0.966594217748044 GO:1990782 protein tyrosine kinase binding 4/970 117/18639 0.0341880341880342 0.656938937351309 0.864325760154449 0.96766200687568 GO:0005125 cytokine activity 9/970 234/18639 0.0384615384615385 0.739056304520222 0.864700215095685 0.96766200687568 GO:0051213 dioxygenase activity 3/970 93/18639 0.032258064516129 0.619853674758896 0.868776448495763 0.96766200687568 GO:0005501 retinoid binding 1/970 38/18639 0.0263157894736842 0.505670103092783 0.869053079966402 0.96766200687568 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/970 38/18639 0.0263157894736842 0.505670103092783 0.869053079966402 0.96766200687568 GO:0019840 isoprenoid binding 1/970 38/18639 0.0263157894736842 0.505670103092783 0.869053079966402 0.96766200687568 GO:0016500 protein-hormone receptor activity 2/970 67/18639 0.0298507462686567 0.57359593783659 0.8701599415441 0.96766200687568 GO:0042054 histone methyltransferase activity 2/970 67/18639 0.0298507462686567 0.57359593783659 0.8701599415441 0.96766200687568 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/970 39/18639 0.0256410256410256 0.492704203013481 0.875881665119491 0.972345294433476 GO:0031267 small GTPase binding 11/970 283/18639 0.03886925795053 0.746890823649412 0.876219904109254 0.972345294433476 GO:0004896 cytokine receptor activity 3/970 96/18639 0.03125 0.60048324742268 0.882306114714335 0.975038799548859 GO:0004532 RNA exonuclease activity 1/970 40/18639 0.025 0.480386597938144 0.882354503013797 0.975038799548859 GO:0032451 demethylase activity 1/970 40/18639 0.025 0.480386597938144 0.882354503013797 0.975038799548859 GO:0071855 neuropeptide receptor binding 1/970 40/18639 0.025 0.480386597938144 0.882354503013797 0.975038799548859 GO:0008528 G protein-coupled peptide receptor activity 4/970 122/18639 0.0327868852459016 0.630015210410681 0.884713685349431 0.976619933879959 GO:0001727 lipid kinase activity 1/970 41/18639 0.024390243902439 0.46866985164697 0.888490108803173 0.97771087286709 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/970 41/18639 0.024390243902439 0.46866985164697 0.888490108803173 0.97771087286709 GO:0140828 metal cation:monoatomic cation antiporter activity 1/970 41/18639 0.024390243902439 0.46866985164697 0.888490108803173 0.97771087286709 GO:0004725 protein tyrosine phosphatase activity 3/970 98/18639 0.0306122448979592 0.588228487271197 0.890621773342905 0.977972919715588 GO:0140996 histone H3 kinase activity 14/970 357/18639 0.0392156862745098 0.753547604608854 0.893188551418536 0.977972919715588 GO:0030695 GTPase regulator activity 20/970 489/18639 0.0408997955010225 0.785908544684081 0.893506070491302 0.977972919715588 GO:0004402 histone acetyltransferase activity 1/970 42/18639 0.0238095238095238 0.457511045655376 0.894306034949045 0.977972919715588 GO:0031492 nucleosomal DNA binding 1/970 42/18639 0.0238095238095238 0.457511045655376 0.894306034949045 0.977972919715588 GO:0051879 Hsp90 protein binding 1/970 42/18639 0.0238095238095238 0.457511045655376 0.894306034949045 0.977972919715588 GO:0060589 nucleoside-triphosphatase regulator activity 20/970 490/18639 0.0408163265306122 0.784304649694929 0.895381942980835 0.978132714450507 GO:0035173 histone kinase activity 14/970 360/18639 0.0388888888888889 0.747268041237113 0.899597139313686 0.981718039997923 GO:0035402 histone H3T11 kinase activity 9/970 247/18639 0.0364372469635627 0.700158604282316 0.901091772456518 0.982330098056224 GO:0001653 peptide receptor activity 4/970 128/18639 0.03125 0.60048324742268 0.905611437134575 0.985298888081612 GO:0042578 phosphoric ester hydrolase activity 14/970 363/18639 0.0385674931129477 0.74109227230127 0.90568823647806 0.985298888081612 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/970 45/18639 0.0222222222222222 0.42701030927835 0.909997851848522 0.988964607587443 GO:0008013 beta-catenin binding 3/970 106/18639 0.0283018867924528 0.543833884458277 0.918855040940539 0.993770779637367 GO:0043495 protein-membrane adaptor activity 1/970 47/18639 0.0212765957446809 0.408839657819697 0.919143506261557 0.993770779637367 GO:0061733 protein-lysine-acetyltransferase activity 1/970 47/18639 0.0212765957446809 0.408839657819697 0.919143506261557 0.993770779637367 GO:0099095 ligand-gated monoatomic anion channel activity 1/970 47/18639 0.0212765957446809 0.408839657819697 0.919143506261557 0.993770779637367 GO:0140938 histone H3 methyltransferase activity 1/970 47/18639 0.0212765957446809 0.408839657819697 0.919143506261557 0.993770779637367 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 19/970 484/18639 0.0392561983471074 0.754326062878078 0.922121937563793 0.995263172003894 GO:0008188 neuropeptide receptor activity 1/970 48/18639 0.0208333333333333 0.400322164948454 0.923362030300191 0.995263172003894 GO:0140693 molecular condensate scaffold activity 1/970 48/18639 0.0208333333333333 0.400322164948454 0.923362030300191 0.995263172003894 GO:0004843 cysteine-type deubiquitinase activity 3/970 108/18639 0.0277777777777778 0.533762886597938 0.924788399146432 0.995780343809668 GO:0016779 nucleotidyltransferase activity 4/970 136/18639 0.0294117647058824 0.56516070345664 0.928225493710983 0.99845932452347 GO:0141003 histone H2AX kinase activity 13/970 354/18639 0.0367231638418079 0.705652629739647 0.930060469374515 0.999411250032676 GO:0001216 DNA-binding transcription activator activity 19/970 491/18639 0.0386965376782077 0.743571923488777 0.932022254296235 0.999999995480277 GO:0005272 sodium channel activity 1/970 51/18639 0.0196078431372549 0.376773802304427 0.934743536555509 0.999999995480277 GO:0030544 Hsp70 protein binding 1/970 51/18639 0.0196078431372549 0.376773802304427 0.934743536555509 0.999999995480277 GO:0004842 ubiquitin-protein transferase activity 17/970 449/18639 0.0378619153674833 0.72753426859229 0.93583511774349 0.999999995480277 GO:0030159 signaling receptor complex adaptor activity 1/970 52/18639 0.0192307692307692 0.369528152260111 0.938148893212554 0.999999995480277 GO:0051018 protein kinase A binding 1/970 53/18639 0.0188679245283019 0.362555922972184 0.941376717691158 0.999999995480277 GO:0015085 calcium ion transmembrane transporter activity 4/970 147/18639 0.0272108843537415 0.522869766463286 0.951348719248374 0.999999995480277 GO:0004879 nuclear receptor activity 1/970 59/18639 0.0169491525423729 0.325685829110606 0.957500967829982 0.999999995480277 GO:0015459 potassium channel regulator activity 1/970 59/18639 0.0169491525423729 0.325685829110606 0.957500967829982 0.999999995480277 GO:0005267 potassium channel activity 3/970 124/18639 0.0241935483870968 0.464890256069172 0.959695510636301 0.999999995480277 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/970 60/18639 0.0166666666666667 0.320257731958763 0.959719700941118 0.999999995480277 GO:0098531 ligand-modulated transcription factor activity 1/970 60/18639 0.0166666666666667 0.320257731958763 0.959719700941118 0.999999995480277 GO:0016755 aminoacyltransferase activity 18/970 496/18639 0.0362903225806452 0.697335384103758 0.961643037395491 0.999999995480277 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 5/970 181/18639 0.0276243093922652 0.53081392037364 0.962040927616921 0.999999995480277 GO:0005249 voltage-gated potassium channel activity 2/970 98/18639 0.0204081632653061 0.392152324847465 0.966418781907007 0.999999995480277 GO:0019787 ubiquitin-like protein transferase activity 17/970 479/18639 0.0354906054279749 0.681968448012397 0.966500774238641 0.999999995480277 GO:0106310 protein serine kinase activity 12/970 361/18639 0.0332409972299169 0.638741182854042 0.966553340460441 0.999999995480277 GO:0035591 signaling adaptor activity 3/970 129/18639 0.0232558139534884 0.446871253895948 0.967012513521546 0.999999995480277 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 7/970 243/18639 0.0288065843621399 0.553531882397862 0.972084269418448 0.999999995480277 GO:0003777 microtubule motor activity 1/970 68/18639 0.0147058823529412 0.28258035172832 0.973772584780721 0.999999995480277 GO:0004676 3-phosphoinositide-dependent protein kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:0004711 ribosomal protein S6 kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:0035175 histone H3S10 kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:0035979 histone H2AXS139 kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:0044022 histone H3S28 kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:0044023 histone H4S1 kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:0044024 histone H2AS1 kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:0044025 histone H2BS14 kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:0072354 histone H3T3 kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:0072371 histone H2AS121 kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:0072518 Rho-dependent protein serine/threonine kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:0140823 histone H2BS36 kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:0140855 histone H3S57 kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:0140995 histone H2A kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:0140997 histone H4 kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:0140998 histone H2B kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:1990244 histone H2AT120 kinase activity 7/970 245/18639 0.0285714285714286 0.549013254786451 0.973788424789175 0.999999995480277 GO:0004677 DNA-dependent protein kinase activity 7/970 246/18639 0.0284552845528455 0.546781493588132 0.974604214805908 0.999999995480277 GO:0140857 histone H3T45 kinase activity 7/970 246/18639 0.0284552845528455 0.546781493588132 0.974604214805908 0.999999995480277 GO:0016279 protein-lysine N-methyltransferase activity 1/970 69/18639 0.0144927536231884 0.278484984311968 0.975142494465859 0.999999995480277 GO:0035403 histone H3T6 kinase activity 7/970 247/18639 0.0283400809716599 0.54456780333069 0.975396619551814 0.999999995480277 GO:0004679 AMP-activated protein kinase activity 7/970 248/18639 0.0282258064516129 0.542371965414034 0.976166229176454 0.999999995480277 GO:0016278 lysine N-methyltransferase activity 1/970 70/18639 0.0142857142857143 0.274506627393225 0.976440920980028 0.999999995480277 GO:0004497 monooxygenase activity 2/970 106/18639 0.0188679245283019 0.362555922972184 0.976640068366446 0.999999995480277 GO:0070851 growth factor receptor binding 3/970 139/18639 0.0215827338129496 0.414722242824297 0.978050720563433 0.999999995480277 GO:0061630 ubiquitin protein ligase activity 11/970 353/18639 0.0311614730878187 0.598782161735931 0.978406092650063 0.999999995480277 GO:0031491 nucleosome binding 1/970 74/18639 0.0135135135135135 0.259668431317916 0.98099147257885 0.999999995480277 GO:0035064 methylated histone binding 1/970 74/18639 0.0135135135135135 0.259668431317916 0.98099147257885 0.999999995480277 GO:0140034 methylation-dependent protein binding 1/970 76/18639 0.0131578947368421 0.252835051546392 0.982925978689449 0.999999995480277 GO:0015370 solute:sodium symporter activity 1/970 79/18639 0.0126582278481013 0.24323372047501 0.985465263493699 0.999999995480277 GO:0061659 ubiquitin-like protein ligase activity 11/970 372/18639 0.0295698924731183 0.568199201862321 0.987375390857736 0.999999995480277 GO:0005096 GTPase activator activity 7/970 271/18639 0.025830258302583 0.496340396393655 0.988766046197496 0.999999995480277 GO:0015276 ligand-gated monoatomic ion channel activity 4/970 186/18639 0.021505376344086 0.413235783172597 0.988838011417316 0.999999995480277 GO:0140375 immune receptor activity 3/970 156/18639 0.0192307692307692 0.369528152260111 0.989216470723403 0.999999995480277 GO:0022834 ligand-gated channel activity 4/970 188/18639 0.0212765957446809 0.408839657819697 0.989683853496998 0.999999995480277 GO:0015079 potassium ion transmembrane transporter activity 3/970 160/18639 0.01875 0.360289948453608 0.99090395273076 0.999999995480277 GO:0015081 sodium ion transmembrane transporter activity 3/970 164/18639 0.0182926829268293 0.351502388735228 0.992335248425273 0.999999995480277 GO:0005262 calcium channel activity 2/970 131/18639 0.0152671755725191 0.293365861336271 0.992677616180287 0.999999995480277 GO:0022836 gated channel activity 8/970 318/18639 0.0251572327044025 0.483407897296246 0.994193129648654 0.999999995480277 GO:0099094 ligand-gated monoatomic cation channel activity 2/970 136/18639 0.0147058823529412 0.28258035172832 0.994216663930964 0.999999995480277 GO:0030527 structural constituent of chromatin 1/970 98/18639 0.0102040816326531 0.196076162423732 0.994760910182452 0.999999995480277 GO:0005244 voltage-gated monoatomic ion channel activity 3/970 173/18639 0.0173410404624277 0.333216137298135 0.994804120056801 0.999999995480277 GO:0003823 antigen binding 3/970 174/18639 0.0172413793103448 0.331301102026306 0.995025224556611 0.999999995480277 GO:0022832 voltage-gated channel activity 3/970 175/18639 0.0171428571428571 0.32940795287187 0.995237186299934 0.999999995480277 GO:0022843 voltage-gated monoatomic cation channel activity 2/970 143/18639 0.013986013986014 0.268747747098263 0.99585141965531 0.999999995480277 GO:0005216 monoatomic ion channel activity 12/970 448/18639 0.0267857142857143 0.514699926362297 0.997177271626536 0.999999995480277 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/970 122/18639 0.00819672131147541 0.15750380260267 0.998558487412617 0.999999995480277 GO:0046873 metal ion transmembrane transporter activity 11/970 450/18639 0.0244444444444444 0.469711340206186 0.998883047254185 0.999999995480277 GO:0140767 enzyme-substrate adaptor activity 1/970 139/18639 0.00719424460431655 0.138240747608099 0.999422715037342 0.999999995480277 GO:0003730 mRNA 3'-UTR binding 4/970 262/18639 0.0152671755725191 0.293365861336271 0.999525970926503 0.999999995480277 GO:0005261 monoatomic cation channel activity 6/970 341/18639 0.0175953079178886 0.338102004413943 0.999723407033265 0.999999995480277 GO:0030371 translation repressor activity 1/970 329/18639 0.00303951367781155 0.0584056654028139 0.999999980328488 0.999999995480277 GO:0045182 translation regulator activity 1/970 356/18639 0.00280898876404494 0.0539760222402409 0.999999995480277 0.999999995480277