category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	43/80	238/9376	21.1747899159664	RPL37/RPS27/RPS6/RPS18/RPL38/RPL37A/RPL36/RPL39/RPL6/RPL21/RPL14/RPS29/RPS16/RPL23/RPL18A/RPL13A/RPLP2/FGG/RPS26/RPS7/RPL24/RPL13/RPL27A/RPS14/RPS11/RPL23A/RPLP0/RPS3A/RPL10/RPL18/RPL34/RPS8/RPL26/RPS4X/RPL29/RPL31/RPL32/RPL28/RPL11/RPS23/RPS13/RPL35/RPLP1	29.2451933423805
Genetic Information Processing	Translation	hsa03010	Ribosome	42/80	222/9376	22.172972972973	RPL37/RPS27/RPS6/RPS18/RPL38/RPL37A/RPL36/RPL39/RPL6/RPL21/RPL14/RPS29/RPS16/RPL23/RPL18A/RPL13A/RPLP2/RPS26/RPS7/RPL24/RPL13/RPL27A/RPS14/RPS11/RPL23A/RPLP0/RPS3A/RPL10/RPL18/RPL34/RPS8/RPL26/RPS4X/RPL29/RPL31/RPL32/RPL28/RPL11/RPS23/RPS13/RPL35/RPLP1	29.6166170941746
NA	NA	hsa04382	Cornified envelope formation	7/80	217/9376	3.78064516129032	KRT19/KRT18/COL4A1/KRT8/COL4A2/KRT7/S100A12	3.84444793418734
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	3/80	50/9376	7.032	HBA2/HBA1/GYPB	3.96717358549127
Metabolism	Energy metabolism	hsa00910	Nitrogen metabolism	2/80	17/9376	13.7882352941176	CA1/GLUD2	4.89556622177253
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	3/80	88/9376	3.99545454545455	TFPI/FGG/SERPINB2	2.61893995064629
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	2/80	37/9376	6.33513513513514	HBA2/HBA1	3.01632874438358
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	3/80	89/9376	3.95056179775281	COL4A1/COL4A2/RELN	2.59444560557881
NA	NA	hsa04518	Integrin signaling	4/80	154/9376	3.04415584415584	COL4A1/FGG/COL4A2/RELN	2.37270845857708
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	3/80	93/9376	3.78064516129032	CCNE1/COL4A1/COL4A2	2.49991616739913
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	2/80	41/9376	5.71707317073171	ALAS2/GCSH	2.80795377712295
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	3/80	99/9376	3.55151515151515	KRT19/KRT18/FGG	2.36752484267424
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	2/80	52/9376	4.50769230769231	CGA/LDLR	2.35290614478872
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	2/80	52/9376	4.50769230769231	LDLR/APOC3	2.35290614478872
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	2/80	54/9376	4.34074074074074	CGA/HLA-G	2.28385053375641
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	6/80	362/9376	1.94254143646409	RPS6/CCNE1/COL4A1/COL4A2/ERBB3/RELN	1.69659637419704
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/80	75/9376	3.12533333333333	CCNE1/RRM2	1.71425504932188
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	4/80	233/9376	2.01201716738197	COL4A1/TPM1/MYOZ2/COL4A2	1.45112242827871
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	2/80	80/9376	2.93	RPS6/ERBB3	1.60818800735377
Metabolism	Metabolism of cofactors and vitamins	hsa00785	Lipoic acid metabolism	1/80	19/9376	6.16842105263158	GCSH	2.09193866376665
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	5/80	333/9376	1.75975975975976	CCNE1/COL4A1/HLA-G/COL4A2/RELN	1.3095579251958
Metabolism	Amino acid metabolism	hsa00220	Arginine biosynthesis	1/80	23/9376	5.09565217391304	GLUD2	1.8242909000473
Organismal Systems	Excretory system	hsa04964	Proximal tubule bicarbonate reclamation	1/80	23/9376	5.09565217391304	GLUD2	1.8242909000473
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/80	101/9376	2.32079207920792	COL4A1/COL4A2	1.23800032221563
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	2/80	103/9376	2.27572815533981	COL4A1/COL4A2	1.20767255586891
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/80	103/9376	2.27572815533981	COL4A1/COL4A2	1.20767255586891
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/80	31/9376	3.78064516129032	GCSH	1.43853138076403
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	3/80	203/9376	1.7320197044335	COL4A1/COL4A2/RELN	0.978132451846269
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	3/80	204/9376	1.72352941176471	RPS6/ERBB3/EZR	0.969218789583294
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	2/80	116/9376	2.02068965517241	GLUD2/GCSH	1.02612386572279
NA	NA	hsa04519	Cadherin signaling	5/80	404/9376	1.45049504950495	KRT19/KRT18/KRT8/PCDHGA4/KRT7	0.858654889200367
Metabolism	Amino acid metabolism	hsa00250	Alanine, aspartate and glutamate metabolism	1/80	37/9376	3.16756756756757	GLUD2	1.22547905420245
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	1/80	39/9376	3.00512820512821	GCSH	1.16400097560193
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/80	39/9376	3.00512820512821	HLA-G	1.16400097560193
NA	NA	hsa04081	Hormone signaling	3/80	219/9376	1.60547945205479	CGA/LEP/DIO2	0.84106088093978
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	4/80	323/9376	1.45139318885449	CCNE1/TPM1/ERBB3/EZR	0.765847989881874
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/80	130/9376	1.80307692307692	COL4A1/COL4A2	0.855331471815029
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/80	44/9376	2.66363636363636	HLA-G	1.02607699792976
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/80	45/9376	2.60444444444444	HLA-G	1.00080489335996
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/80	46/9376	2.54782608695652	ALAS2	0.976209051360726
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	2/80	139/9376	1.6863309352518	KRT19/KRT18	0.756237269727456
NA	NA	hsa03272	Virion - Hepatitis viruses	1/80	48/9376	2.44166666666667	LDLR	0.928910305899481
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/80	155/9376	1.51225806451613	LDLR/CCNE1	0.596551876984666
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	2/80	157/9376	1.49299363057325	CCNE1/HLA-G	0.577872198703625
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	2/80	158/9376	1.48354430379747	CCNE1/CDKN1C	0.5686290425521
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/80	160/9376	1.465	HLA-G/L1CAM	0.550331390492143
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/80	59/9376	1.9864406779661	RRM2	0.705085048179421
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/80	59/9376	1.9864406779661	RRM2	0.705085048179421
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/80	59/9376	1.9864406779661	CGA	0.705085048179421
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/80	65/9376	1.80307692307692	LDLR	0.602695897856979
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/80	65/9376	1.80307692307692	CGA	0.602695897856979
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/80	70/9376	1.67428571428571	LEP	0.525283826050388
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/80	70/9376	1.67428571428571	HLA-G	0.525283826050388
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/80	71/9376	1.65070422535211	CGA	0.510548714038414
NA	NA	hsa04517	IgSF CAM signaling	3/80	299/9376	1.17591973244147	L1CAM/FGG/EZR	0.286788383760348
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/80	75/9376	1.56266666666667	CGA	0.453836656721351
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/80	76/9376	1.54210526315789	APOC3	0.440181230158526
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/80	76/9376	1.54210526315789	EZR	0.440181230158526
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/80	82/9376	1.42926829268293	RRM2	0.362173756262142
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/80	82/9376	1.42926829268293	HLA-G	0.362173756262142
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/80	85/9376	1.37882352941176	RRM2	0.32546009957275
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/80	86/9376	1.36279069767442	ERBB3	0.313530709739528
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	2/80	205/9376	1.14341463414634	CCNE1/HLA-G	0.192594831133054
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	2/80	205/9376	1.14341463414634	CCNE1/HLA-G	0.192594831133054
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	1/80	87/9376	1.34712643678161	TPM1	0.301748701142452
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/80	90/9376	1.30222222222222	LDLR	0.267248873846756
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/80	93/9376	1.26021505376344	CGA	0.233944204373778
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	2/80	216/9376	1.08518518518519	LDLR/CCL3L1	0.117496731259751
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/80	95/9376	1.23368421052632	CCL3L1	0.212361781337799
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/80	98/9376	1.19591836734694	LDLR	0.180860439114652
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/80	224/9376	1.04642857142857	CCNE1/HLA-G	0.0652429964017257
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/80	99/9376	1.18383838383838	PCYT1B	0.170581758260773
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/80	99/9376	1.18383838383838	TPM1	0.170581758260773
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/80	100/9376	1.172	CCL3L1	0.160409709048837
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	2/80	227/9376	1.03259911894273	CCL3L1/HLA-G	0.0461226818139807
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/80	103/9376	1.1378640776699	CCL3L1	0.130509515170004
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/80	104/9376	1.12692307692308	PCYT1B	0.120740542888842
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	2/80	232/9376	1.01034482758621	CHRM5/EZR	0.0148006815587401
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/80	105/9376	1.11619047619048	TPM1	0.11106685252855
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/80	106/9376	1.10566037735849	CCNE1	0.101486388308871
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/80	109/9376	1.07522935779817	CCL3L1	0.0732847475391476
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/80	110/9376	1.06545454545455	RPS6	0.0640578827334169
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	3/80	370/9376	0.95027027027027	CGA/LEP/CHRM5	-0.0905385560388308
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/80	112/9376	1.04642857142857	LDLR	0.0458540429342902
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/80	115/9376	1.01913043478261	CHRM5	0.0191481752099759
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/80	116/9376	1.01034482758621	EZR	0.0103999040444878
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	2/80	250/9376	0.9376	LDLR/HLA-G	-0.0927677313474139
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/80	254/9376	0.922834645669291	ERBB3/CHRM5	-0.115658286342533
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/80	122/9376	0.960655737704918	LEP	-0.0405769265307334
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/80	122/9376	0.960655737704918	DIO2	-0.0405769265307334
Organismal Systems	Immune system	hsa04611	Platelet activation	1/80	126/9376	0.93015873015873	FGG	-0.0732165241281627
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	1/80	128/9376	0.915625	RRM2	-0.0891615139843511
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/80	133/9376	0.881203007518797	HLA-G	-0.127999232074313
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/80	136/9376	0.861764705882353	CCNE1	-0.15063815354056
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/80	138/9376	0.849275362318841	CCNE1	-0.165469283735231
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/80	138/9376	0.849275362318841	RPS6	-0.165469283735231
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/80	140/9376	0.837142857142857	RPS6	-0.180099057976658
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/80	144/9376	0.813888888888889	RELN	-0.208779678388699
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/80	150/9376	0.781333333333333	CCNE1	-0.250440212272662
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/80	298/9376	0.786577181208054	LEP/CCL3L1	-0.347325339247352
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/80	154/9376	0.761038961038961	ALAS2	-0.277368714344461
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/80	154/9376	0.761038961038961	TPM1	-0.277368714344461
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	1/80	155/9376	0.756129032258064	HLA-G	-0.284000767632498
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/80	156/9376	0.751282051282051	LDLR	-0.290593931110637
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	1/80	157/9376	0.746496815286624	LEP	-0.297148753338557
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/80	158/9376	0.741772151898734	RPS6	-0.303665771415257
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/80	163/9376	0.719018404907976	CCNE1	-0.335701834393631
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/80	168/9376	0.697619047619048	GLUD2	-0.366867288842588
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/80	168/9376	0.697619047619048	LEP	-0.366867288842588
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/80	170/9376	0.689411764705882	EZR	-0.37910241474911
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/80	178/9376	0.658426966292135	NOTUM	-0.426804951993262
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/80	180/9376	0.651111111111111	HLA-G	-0.4384362798228
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/80	184/9376	0.63695652173913	L1CAM	-0.46136550168584
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/80	193/9376	0.607253886010363	CCL3L1	-0.511423680272985
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/80	194/9376	0.604123711340206	TPM1	-0.51686162067356
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/80	195/9376	0.601025641025641	FGG	-0.5222757624897
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/80	196/9376	0.597959183673469	HLA-G	-0.527666369284867
NA	NA	hsa04082	Neuroactive ligand signaling	1/80	199/9376	0.58894472361809	CHRM5	-0.543699550293743
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/80	200/9376	0.586	EZR	-0.548998566780055
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/80	214/9376	0.547663551401869	HLA-G	-0.620948955778297
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/80	226/9376	0.51858407079646	CGA	-0.679589566891926
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	1/80	235/9376	0.498723404255319	RPS6	-0.721933307332808
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/80	248/9376	0.47258064516129	RHOJ	-0.780866267171106
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	1/80	300/9376	0.390666666666667	ERBB3	-0.995063725597739
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	1/80	388/9376	0.302061855670103	CHRM5	-1.3025183173672
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	1/80	480/9376	0.244166666666667	CHRM5	-1.57700055711372