ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 80/551 175/18639 0.457142857142857 15.464039408867 1.75564209177949e-75 1.38169032623045e-72 GO:0004601 peroxidase activity 18/551 57/18639 0.315789473684211 10.6823956442831 2.40568398355696e-14 9.46636647529664e-12 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 18/551 59/18639 0.305084745762712 10.3202805376973 4.75144038269915e-14 1.24646119372808e-11 GO:0019843 rRNA binding 18/551 65/18639 0.276923076923077 9.36763925729443 3.09995503718625e-13 6.09916153566395e-11 GO:0048027 mRNA 5'-UTR binding 12/551 24/18639 0.5 16.9137931034483 7.74330026890644e-13 1.21879546232587e-10 GO:0031720 haptoglobin binding 8/551 10/18639 0.8 27.0620689655172 2.36990617471499e-11 3.10852693250117e-09 GO:0016209 antioxidant activity 18/551 86/18639 0.209302325581395 7.08019246190858 5.33684949606722e-11 6.00014364772129e-09 GO:0005344 oxygen carrier activity 8/551 14/18639 0.571428571428571 19.3300492610837 1.42404139257574e-09 1.27280442286123e-07 GO:0045296 cadherin binding 33/551 334/18639 0.0988023952095808 3.34224654139996 1.45555778980319e-09 1.27280442286123e-07 GO:1990948 ubiquitin ligase inhibitor activity 7/551 11/18639 0.636363636363636 21.5266457680251 5.65661698662013e-09 4.45175756847005e-07 GO:0055105 ubiquitin-protein transferase inhibitor activity 7/551 15/18639 0.466666666666667 15.7862068965517 9.94781460297516e-08 7.11720917503769e-06 GO:0019825 oxygen binding 9/551 34/18639 0.264705882352941 8.95436105476673 4.37898761852478e-07 2.8718860464825e-05 GO:0098632 cell-cell adhesion mediator activity 11/551 55/18639 0.2 6.76551724137931 5.01942807244147e-07 3.03868453308572e-05 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 12/551 68/18639 0.176470588235294 5.96957403651116 6.36787573689844e-07 3.57965586067077e-05 GO:0009055 electron transfer activity 15/551 116/18639 0.129310344827586 4.37425683709869 1.67569693947651e-06 8.79182327578674e-05 GO:0098631 cell adhesion mediator activity 12/551 76/18639 0.157894736842105 5.34119782214156 2.18826940276661e-06 0.000107635501248582 GO:0004129 cytochrome-c oxidase activity 6/551 15/18639 0.4 13.5310344827586 2.589537675312e-06 0.000119880361792385 GO:0004602 glutathione peroxidase activity 7/551 23/18639 0.304347826086957 10.2953523238381 3.08394480731324e-06 0.000134836920186418 GO:0044389 ubiquitin-like protein ligase binding 26/551 322/18639 0.0807453416149068 2.73142000428357 3.91394844106478e-06 0.000158968213713808 GO:0016675 oxidoreductase activity, acting on a heme group of donors 6/551 16/18639 0.375 12.6853448275862 4.03985295333693e-06 0.000158968213713808 GO:0055106 ubiquitin-protein transferase regulator activity 8/551 36/18639 0.222222222222222 7.51724137931035 8.07799138658695e-06 0.000302732343868759 GO:0001968 fibronectin binding 7/551 30/18639 0.233333333333333 7.89310344827586 2.13948052331056e-05 0.000765350532657003 GO:0016860 intramolecular oxidoreductase activity 9/551 53/18639 0.169811320754717 5.74430709173715 2.24429983285593e-05 0.000767940855851138 GO:0140517 protein-RNA adaptor activity 6/551 22/18639 0.272727272727273 9.2257053291536 3.23532219021167e-05 0.00106091606820691 GO:0015399 primary active transmembrane transporter activity 16/551 166/18639 0.0963855421686747 3.26049023680931 3.45675474093887e-05 0.00107529364996164 GO:0031625 ubiquitin protein ligase binding 23/551 302/18639 0.076158940397351 2.57627312171729 3.55243137217315e-05 0.00107529364996164 GO:0022853 active monoatomic ion transmembrane transporter activity 13/551 118/18639 0.110169491525424 3.72676797194623 4.66827421046158e-05 0.00136071548282714 GO:0004857 enzyme inhibitor activity 28/551 416/18639 0.0673076923076923 2.27685676392573 4.90652997921054e-05 0.00137908539058525 GO:0015078 proton transmembrane transporter activity 16/551 185/18639 0.0864864864864865 2.92562907735322 0.000126616758412809 0.00343611685761658 GO:0015036 disulfide oxidoreductase activity 7/551 40/18639 0.175 5.9198275862069 0.000151687272393098 0.00397926277911227 GO:0008301 DNA binding, bending 5/551 19/18639 0.263157894736842 8.90199637023593 0.000182747332752186 0.00463942422180549 GO:0048407 platelet-derived growth factor binding 4/551 11/18639 0.363636363636364 12.3009404388715 0.00021125260300228 0.00519549370508731 GO:0030020 extracellular matrix structural constituent conferring tensile strength 7/551 44/18639 0.159090909090909 5.38166144200627 0.000281532625134987 0.00671412654488591 GO:0016853 isomerase activity 15/551 180/18639 0.0833333333333333 2.81896551724138 0.000305558805627368 0.00695906884922311 GO:1990247 N6-methyladenosine-containing RNA reader activity 4/551 12/18639 0.333333333333333 11.2758620689655 0.00030948844945719 0.00695906884922311 GO:0015035 protein-disulfide reductase activity 6/551 34/18639 0.176470588235294 5.96957403651116 0.000431483276266961 0.00928709324970607 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 4/551 13/18639 0.307692307692308 10.4084880636605 0.0004366231896304 0.00928709324970607 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 7/551 48/18639 0.145833333333333 4.93318965517241 0.00048854410387324 0.0101180055196905 GO:0008135 translation factor activity, RNA binding 9/551 83/18639 0.108433734939759 3.66805151641047 0.000760241237806802 0.0153412783116398 GO:0180051 translation factor activity 9/551 84/18639 0.107142857142857 3.6243842364532 0.000829621145414365 0.0163227960360276 GO:0051082 unfolded protein binding 11/551 121/18639 0.0909090909090909 3.07523510971787 0.000927485826731031 0.0178032035521298 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 7/551 54/18639 0.12962962962963 4.38505747126437 0.00100894336351567 0.0189056768354008 GO:0017070 U6 snRNA binding 4/551 16/18639 0.25 8.45689655172414 0.00103566571319736 0.0189550910764261 GO:0008017 microtubule binding 18/551 276/18639 0.0652173913043478 2.20614692653673 0.00150798698851675 0.0269724036355156 GO:0098641 cadherin binding involved in cell-cell adhesion 4/551 18/18639 0.222222222222222 7.51724137931035 0.00166145130044415 0.0290569371877677 GO:0003756 protein disulfide isomerase activity 4/551 19/18639 0.210526315789474 7.12159709618875 0.00205577235849534 0.0344232520454432 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 4/551 19/18639 0.210526315789474 7.12159709618875 0.00205577235849534 0.0344232520454432 GO:0019838 growth factor binding 11/551 136/18639 0.0808823529411765 2.73605476673428 0.00238330469565297 0.0390762665724768 GO:0035374 chondroitin sulfate binding 3/551 10/18639 0.3 10.148275862069 0.00263983567899708 0.0423989934565449 GO:0003697 single-stranded DNA binding 10/551 121/18639 0.0826446280991736 2.7956682815617 0.00316557601700747 0.0498261665076975 GO:0020037 heme binding 11/551 142/18639 0.0774647887323944 2.6204468188441 0.00333311352039478 0.0514345164813861 GO:0070990 snRNP binding 3/551 11/18639 0.272727272727273 9.2257053291536 0.00355055433249512 0.0537362742244935 GO:0003743 translation initiation factor activity 6/551 51/18639 0.117647058823529 3.97971602434077 0.00378443614187637 0.0561953064840888 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 3/551 12/18639 0.25 8.45689655172414 0.00463090962684109 0.0662641068422534 GO:0097371 MDM2/MDM4 family protein binding 3/551 12/18639 0.25 8.45689655172414 0.00463090962684109 0.0662641068422534 GO:0046906 tetrapyrrole binding 11/551 152/18639 0.0723684210526316 2.44804900181488 0.00556998212144944 0.0782781415996555 GO:0005539 glycosaminoglycan binding 15/551 242/18639 0.0619834710743802 2.09675121117127 0.00575183773580839 0.0794157245277404 GO:0031994 insulin-like growth factor I binding 3/551 13/18639 0.230769230769231 7.80636604774536 0.0058891955580043 0.0799102914508515 GO:0005200 structural constituent of cytoskeleton 9/551 112/18639 0.0803571428571429 2.7182881773399 0.00600207861727342 0.0800616249456641 GO:0042277 peptide binding 15/551 249/18639 0.0602409638554217 2.03780639800582 0.00741493223443185 0.0972591944749644 GO:0031492 nucleosomal DNA binding 5/551 42/18639 0.119047619047619 4.02709359605911 0.00765013997533138 0.0986993468948491 GO:1901681 sulfur compound binding 16/551 275/18639 0.0581818181818182 1.96815047021944 0.00799522209078489 0.101487738474963 GO:0016835 carbon-oxygen lyase activity 7/551 79/18639 0.0886075949367089 2.99738105630729 0.00879292009628254 0.105326812555535 GO:0097718 disordered domain specific binding 4/551 28/18639 0.142857142857143 4.83251231527094 0.00880508259593616 0.105326812555535 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 3/551 15/18639 0.2 6.76551724137931 0.00896683156444835 0.105326812555535 GO:0031386 protein tag activity 3/551 15/18639 0.2 6.76551724137931 0.00896683156444835 0.105326812555535 GO:0141047 molecular tag activity 3/551 15/18639 0.2 6.76551724137931 0.00896683156444835 0.105326812555535 GO:0048306 calcium-dependent protein binding 7/551 80/18639 0.0875 2.95991379310345 0.00939781858052663 0.108765929748154 GO:0022804 active transmembrane transporter activity 23/551 457/18639 0.050328227571116 1.70248245680223 0.00956647283121696 0.109113248089388 GO:0001618 virus receptor activity 7/551 81/18639 0.0864197530864197 2.92337164750958 0.0100325945218945 0.112795026981871 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 9/551 122/18639 0.0737704918032787 2.49547767100057 0.0103059366743718 0.114236227644093 GO:0140272 exogenous protein binding 7/551 82/18639 0.0853658536585366 2.88772077375946 0.0106980564311749 0.116401618873208 GO:0005159 insulin-like growth factor receptor binding 3/551 16/18639 0.1875 6.3426724137931 0.0107971006070447 0.116401618873208 GO:0015631 tubulin binding 20/551 385/18639 0.051948051948052 1.75727720555307 0.0109506065151521 0.116461180100333 GO:0008201 heparin binding 11/551 172/18639 0.063953488372093 2.16339214113873 0.0134603333329257 0.141243764440167 GO:0003746 translation elongation factor activity 3/551 18/18639 0.166666666666667 5.63793103448276 0.0150604520704646 0.155954944466522 GO:0016829 lyase activity 12/551 200/18639 0.06 2.02965517241379 0.0160895839812017 0.164448085626049 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 9/551 132/18639 0.0681818181818182 2.3064263322884 0.0166003037008216 0.167492807853161 GO:0061134 peptidase regulator activity 13/551 226/18639 0.0575221238938053 1.94583460482148 0.0172640190889725 0.170019491721643 GO:0005520 insulin-like growth factor binding 3/551 19/18639 0.157894736842105 5.34119782214156 0.0174988295164589 0.170019491721643 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 3/551 19/18639 0.157894736842105 5.34119782214156 0.0174988295164589 0.170019491721643 GO:0005080 protein kinase C binding 5/551 52/18639 0.0961538461538462 3.2526525198939 0.0183961600158567 0.176558267469259 GO:0051287 NAD binding 5/551 54/18639 0.0925925925925926 3.13218390804598 0.0213438757045247 0.202381086499529 GO:0031491 nucleosome binding 6/551 74/18639 0.0810810810810811 2.74277726001864 0.0221227404646778 0.207269008877398 GO:0019208 phosphatase regulator activity 8/551 117/18639 0.0683760683760684 2.31299734748011 0.0228528664890875 0.208024020453635 GO:0070182 DNA polymerase binding 3/551 21/18639 0.142857142857143 4.83251231527094 0.0229963021340104 0.208024020453635 GO:0072542 protein phosphatase activator activity 3/551 21/18639 0.142857142857143 4.83251231527094 0.0229963021340104 0.208024020453635 GO:0019212 phosphatase inhibitor activity 5/551 56/18639 0.0892857142857143 3.02032019704433 0.0245830184830714 0.219850403933832 GO:0070034 telomerase RNA binding 3/551 22/18639 0.136363636363636 4.6128526645768 0.0260561955445816 0.230407032512199 GO:0000217 DNA secondary structure binding 4/551 39/18639 0.102564102564103 3.46949602122016 0.0274522653238614 0.240054808998655 GO:0005201 extracellular matrix structural constituent 10/551 168/18639 0.0595238095238095 2.01354679802956 0.027900028636401 0.240566481555529 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 5/551 58/18639 0.0862068965517241 2.91617122473246 0.0281221299912436 0.240566481555529 GO:0030414 peptidase inhibitor activity 10/551 169/18639 0.0591715976331361 2.00163231993471 0.0289050198162419 0.244604845111639 GO:0017134 fibroblast growth factor binding 3/551 23/18639 0.130434782608696 4.41229385307346 0.0293230019816646 0.245502154889043 GO:0008137 NADH dehydrogenase (ubiquinone) activity 4/551 41/18639 0.0975609756097561 3.30025231286796 0.0322892507434926 0.266083962778286 GO:0005540 hyaluronic acid binding 3/551 24/18639 0.125 4.22844827586207 0.0327956091353161 0.266083962778286 GO:0015295 solute:proton symporter activity 3/551 24/18639 0.125 4.22844827586207 0.0327956091353161 0.266083962778286 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/551 10/18639 0.2 6.76551724137931 0.0335428917737423 0.26664904874682 GO:0030957 Tat protein binding 2/551 10/18639 0.2 6.76551724137931 0.0335428917737423 0.26664904874682 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 5/551 61/18639 0.0819672131147541 2.77275296777841 0.0340089276286873 0.267650260437769 GO:0140104 molecular carrier activity 13/551 249/18639 0.0522088353413655 1.76609887827171 0.0344683838157553 0.268580376861381 GO:0008307 structural constituent of muscle 4/551 42/18639 0.0952380952380952 3.22167487684729 0.0348828413506675 0.269145060225248 GO:0019211 phosphatase activator activity 3/551 25/18639 0.12 4.05931034482759 0.0364723855440787 0.277061210987194 GO:0043021 ribonucleoprotein complex binding 10/551 177/18639 0.0564971751412429 1.91116306253653 0.0378845592532712 0.277061210987194 GO:0019888 protein phosphatase regulator activity 7/551 107/18639 0.0654205607476635 2.2130196583951 0.039456809212297 0.277061210987194 GO:0005536 D-glucose binding 2/551 11/18639 0.181818181818182 6.15047021943574 0.040207855649575 0.277061210987194 GO:0010854 adenylate cyclase regulator activity 2/551 11/18639 0.181818181818182 6.15047021943574 0.040207855649575 0.277061210987194 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/551 11/18639 0.181818181818182 6.15047021943574 0.040207855649575 0.277061210987194 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/551 11/18639 0.181818181818182 6.15047021943574 0.040207855649575 0.277061210987194 GO:0019206 nucleoside kinase activity 2/551 11/18639 0.181818181818182 6.15047021943574 0.040207855649575 0.277061210987194 GO:0032794 GTPase activating protein binding 2/551 11/18639 0.181818181818182 6.15047021943574 0.040207855649575 0.277061210987194 GO:0045294 alpha-catenin binding 2/551 11/18639 0.181818181818182 6.15047021943574 0.040207855649575 0.277061210987194 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/551 11/18639 0.181818181818182 6.15047021943574 0.040207855649575 0.277061210987194 GO:0003954 NADH dehydrogenase activity 4/551 44/18639 0.0909090909090909 3.07523510971787 0.0404223256899044 0.277061210987194 GO:0019887 protein kinase regulator activity 13/551 255/18639 0.0509803921568627 1.72454361054767 0.0404854374377729 0.277061210987194 GO:0038024 cargo receptor activity 5/551 65/18639 0.0769230769230769 2.60212201591512 0.0429658831001095 0.291501293101605 GO:0004364 glutathione transferase activity 3/551 27/18639 0.111111111111111 3.75862068965517 0.0444295823333366 0.296322722850304 GO:0008320 protein transmembrane transporter activity 3/551 27/18639 0.111111111111111 3.75862068965517 0.0444295823333366 0.296322722850304 GO:0019207 kinase regulator activity 14/551 287/18639 0.0487804878048781 1.65012615643398 0.0468208100957864 0.300349949195112 GO:0061135 endopeptidase regulator activity 10/551 184/18639 0.0543478260869565 1.83845577211394 0.0471851486775242 0.300349949195112 GO:0004859 phospholipase inhibitor activity 2/551 12/18639 0.166666666666667 5.63793103448276 0.0473232448541218 0.300349949195112 GO:0005049 nuclear export signal receptor activity 2/551 12/18639 0.166666666666667 5.63793103448276 0.0473232448541218 0.300349949195112 GO:0010853 cyclase activator activity 2/551 12/18639 0.166666666666667 5.63793103448276 0.0473232448541218 0.300349949195112 GO:0015132 prostaglandin transmembrane transporter activity 2/551 12/18639 0.166666666666667 5.63793103448276 0.0473232448541218 0.300349949195112 GO:0004866 endopeptidase inhibitor activity 9/551 161/18639 0.0559006211180124 1.89098307988863 0.0500376929013681 0.312537018360133 GO:0005178 integrin binding 9/551 161/18639 0.0559006211180124 1.89098307988863 0.0500376929013681 0.312537018360133 GO:0072341 modified amino acid binding 6/551 91/18639 0.0659340659340659 2.23039029935582 0.0527397069235586 0.319794292454021 GO:0043236 laminin binding 3/551 29/18639 0.103448275862069 3.49940546967895 0.0531727456813446 0.319794292454021 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 2/551 13/18639 0.153846153846154 5.20424403183024 0.0548567083625068 0.319794292454021 GO:0005542 folic acid binding 2/551 13/18639 0.153846153846154 5.20424403183024 0.0548567083625068 0.319794292454021 GO:0008035 high-density lipoprotein particle binding 2/551 13/18639 0.153846153846154 5.20424403183024 0.0548567083625068 0.319794292454021 GO:0008253 5'-nucleotidase activity 2/551 13/18639 0.153846153846154 5.20424403183024 0.0548567083625068 0.319794292454021 GO:0019855 calcium channel inhibitor activity 2/551 13/18639 0.153846153846154 5.20424403183024 0.0548567083625068 0.319794292454021 GO:0071714 icosanoid transmembrane transporter activity 2/551 13/18639 0.153846153846154 5.20424403183024 0.0548567083625068 0.319794292454021 GO:0071837 HMG box domain binding 2/551 13/18639 0.153846153846154 5.20424403183024 0.0548567083625068 0.319794292454021 GO:0097110 scaffold protein binding 5/551 70/18639 0.0714285714285714 2.41625615763547 0.0559797736643604 0.323941778484203 GO:0004867 serine-type endopeptidase inhibitor activity 6/551 95/18639 0.0631578947368421 2.13647912885662 0.0624669600015243 0.355437555674888 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 2/551 14/18639 0.142857142857143 4.83251231527094 0.0627774081814606 0.355437555674888 GO:0044548 S100 protein binding 2/551 14/18639 0.142857142857143 4.83251231527094 0.0627774081814606 0.355437555674888 GO:0043539 protein serine/threonine kinase activator activity 5/551 73/18639 0.0684931506849315 2.31695795937648 0.064763714095899 0.364064592810518 GO:0022884 macromolecule transmembrane transporter activity 3/551 32/18639 0.09375 3.17133620689655 0.0676994419964253 0.372583642315991 GO:0031369 translation initiation factor binding 3/551 32/18639 0.09375 3.17133620689655 0.0676994419964253 0.372583642315991 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/551 32/18639 0.09375 3.17133620689655 0.0676994419964253 0.372583642315991 GO:0044183 protein folding chaperone 5/551 75/18639 0.0666666666666667 2.2551724137931 0.0710240643826018 0.380817221977021 GO:0008252 nucleotidase activity 2/551 15/18639 0.133333333333333 4.51034482758621 0.0710559584302317 0.380817221977021 GO:0016846 carbon-sulfur lyase activity 2/551 15/18639 0.133333333333333 4.51034482758621 0.0710559584302317 0.380817221977021 GO:0004864 protein phosphatase inhibitor activity 4/551 53/18639 0.0754716981132075 2.5530253741054 0.0711310440033318 0.380817221977021 GO:0003925 G protein activity 4/551 54/18639 0.0740740740740741 2.50574712643678 0.0751140174672363 0.396743166085335 GO:0017069 snRNA binding 4/551 54/18639 0.0740740740740741 2.50574712643678 0.0751140174672363 0.396743166085335 GO:0055102 lipase inhibitor activity 2/551 16/18639 0.125 4.22844827586207 0.079664366690687 0.417972377237138 GO:0030170 pyridoxal phosphate binding 4/551 56/18639 0.0714285714285714 2.41625615763547 0.0834090164897569 0.425056672736229 GO:0016229 steroid dehydrogenase activity 3/551 35/18639 0.0857142857142857 2.89950738916256 0.0838192203497419 0.425056672736229 GO:0061631 ubiquitin conjugating enzyme activity 3/551 35/18639 0.0857142857142857 2.89950738916256 0.0838192203497419 0.425056672736229 GO:0046332 SMAD binding 5/551 79/18639 0.0632911392405063 2.14098646879092 0.0845020943554876 0.425056672736229 GO:0031490 chromatin DNA binding 7/551 128/18639 0.0546875 1.84994612068966 0.0855954367768555 0.425056672736229 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 7/551 128/18639 0.0546875 1.84994612068966 0.0855954367768555 0.425056672736229 GO:0005506 iron ion binding 8/551 154/18639 0.051948051948052 1.75727720555307 0.086994953287676 0.425056672736229 GO:0070279 vitamin B6 binding 4/551 57/18639 0.0701754385964912 2.37386569872958 0.0877180296984151 0.425056672736229 GO:0008429 phosphatidylethanolamine binding 2/551 17/18639 0.117647058823529 3.97971602434077 0.0885759775460503 0.425056672736229 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/551 17/18639 0.117647058823529 3.97971602434077 0.0885759775460503 0.425056672736229 GO:0016018 cyclosporin A binding 2/551 17/18639 0.117647058823529 3.97971602434077 0.0885759775460503 0.425056672736229 GO:0046965 nuclear retinoid X receptor binding 2/551 17/18639 0.117647058823529 3.97971602434077 0.0885759775460503 0.425056672736229 GO:0070492 oligosaccharide binding 2/551 17/18639 0.117647058823529 3.97971602434077 0.0885759775460503 0.425056672736229 GO:1990226 histone methyltransferase binding 2/551 17/18639 0.117647058823529 3.97971602434077 0.0885759775460503 0.425056672736229 GO:0042805 actinin binding 3/551 37/18639 0.0810810810810811 2.74277726001864 0.0953875538235657 0.452228944934616 GO:0043394 proteoglycan binding 3/551 37/18639 0.0810810810810811 2.74277726001864 0.0953875538235657 0.452228944934616 GO:0000400 four-way junction DNA binding 2/551 18/18639 0.111111111111111 3.75862068965517 0.0977654182304986 0.452596377337661 GO:0008525 phosphatidylcholine transporter activity 2/551 18/18639 0.111111111111111 3.75862068965517 0.0977654182304986 0.452596377337661 GO:0031690 adrenergic receptor binding 2/551 18/18639 0.111111111111111 3.75862068965517 0.0977654182304986 0.452596377337661 GO:1901611 phosphatidylglycerol binding 2/551 18/18639 0.111111111111111 3.75862068965517 0.0977654182304986 0.452596377337661 GO:0043531 ADP binding 3/551 38/18639 0.0789473684210526 2.67059891107078 0.101402988184675 0.466690945621866 GO:0051087 protein-folding chaperone binding 7/551 134/18639 0.0522388059701493 1.76711271230057 0.10278153597263 0.470285283781741 GO:0031406 carboxylic acid binding 9/551 187/18639 0.0481283422459893 1.62806564632122 0.103764378865599 0.472037954723854 GO:0016836 hydro-lyase activity 4/551 61/18639 0.0655737704918033 2.21820237422272 0.105991101494604 0.479396533771573 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 2/551 19/18639 0.105263157894737 3.56079854809437 0.107208546314503 0.481537383145396 GO:0004222 metalloendopeptidase activity 6/551 110/18639 0.0545454545454545 1.84514106583072 0.107688156840648 0.481537383145396 GO:0043177 organic acid binding 9/551 189/18639 0.0476190476190476 1.61083743842365 0.108890513272804 0.484162903648006 GO:0071949 FAD binding 3/551 40/18639 0.075 2.53706896551724 0.113869842174196 0.502658187383179 GO:0043022 ribosome binding 6/551 112/18639 0.0535714285714286 1.8121921182266 0.114729384267415 0.502658187383179 GO:0005507 copper ion binding 4/551 63/18639 0.0634920634920635 2.14778325123153 0.115723251782528 0.502658187383179 GO:0010851 cyclase regulator activity 2/551 20/18639 0.1 3.38275862068966 0.116882399353395 0.502658187383179 GO:0016004 phospholipase activator activity 2/551 20/18639 0.1 3.38275862068966 0.116882399353395 0.502658187383179 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/551 20/18639 0.1 3.38275862068966 0.116882399353395 0.502658187383179 GO:0016651 oxidoreductase activity, acting on NAD(P)H 5/551 88/18639 0.0568181818181818 1.92202194357367 0.119306318692508 0.506333137690601 GO:0017080 sodium channel regulator activity 3/551 41/18639 0.0731707317073171 2.47518923465097 0.120310415181884 0.506333137690601 GO:0061650 ubiquitin-like protein conjugating enzyme activity 3/551 41/18639 0.0731707317073171 2.47518923465097 0.120310415181884 0.506333137690601 GO:0140318 protein transporter activity 3/551 41/18639 0.0731707317073171 2.47518923465097 0.120310415181884 0.506333137690601 GO:0001846 opsonin binding 2/551 21/18639 0.0952380952380952 3.22167487684729 0.12676514642912 0.520083076254414 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/551 21/18639 0.0952380952380952 3.22167487684729 0.12676514642912 0.520083076254414 GO:0051428 peptide hormone receptor binding 2/551 21/18639 0.0952380952380952 3.22167487684729 0.12676514642912 0.520083076254414 GO:0019894 kinesin binding 3/551 42/18639 0.0714285714285714 2.41625615763547 0.126881767015054 0.520083076254414 GO:0042056 chemoattractant activity 3/551 42/18639 0.0714285714285714 2.41625615763547 0.126881767015054 0.520083076254414 GO:0004712 protein serine/threonine/tyrosine kinase activity 3/551 43/18639 0.0697674418604651 2.36006415396953 0.133578365697569 0.540211936255589 GO:0008200 ion channel inhibitor activity 3/551 43/18639 0.0697674418604651 2.36006415396953 0.133578365697569 0.540211936255589 GO:0046982 protein heterodimerization activity 15/551 369/18639 0.040650406504065 1.37510513036165 0.133851750406404 0.540211936255589 GO:0140297 DNA-binding transcription factor binding 19/551 488/18639 0.0389344262295082 1.31705765969474 0.136098277885386 0.546476248447952 GO:0005243 gap junction channel activity 2/551 22/18639 0.0909090909090909 3.07523510971787 0.136836041517573 0.546649566874772 GO:0016248 channel inhibitor activity 3/551 44/18639 0.0681818181818182 2.3064263322884 0.140394661307886 0.555229137936214 GO:0019205 nucleobase-containing compound kinase activity 3/551 44/18639 0.0681818181818182 2.3064263322884 0.140394661307886 0.555229137936214 GO:0003777 microtubule motor activity 4/551 68/18639 0.0588235294117647 1.98985801217039 0.14165497640543 0.557412332155366 GO:0005158 insulin receptor binding 2/551 23/18639 0.0869565217391304 2.94152923538231 0.147075378616231 0.568357120588923 GO:0099186 structural constituent of postsynapse 2/551 23/18639 0.0869565217391304 2.94152923538231 0.147075378616231 0.568357120588923 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/551 23/18639 0.0869565217391304 2.94152923538231 0.147075378616231 0.568357120588923 GO:0141110 transporter inhibitor activity 3/551 45/18639 0.0666666666666667 2.2551724137931 0.147325098602465 0.568357120588923 GO:0008028 monocarboxylic acid transmembrane transporter activity 4/551 70/18639 0.0571428571428571 1.93300492610837 0.152619762065948 0.585910989004395 GO:0019842 vitamin binding 7/551 150/18639 0.0466666666666667 1.57862068965517 0.156841339645392 0.598669183690028 GO:0060229 lipase activator activity 2/551 24/18639 0.0833333333333333 2.81896551724138 0.157464448569042 0.598669183690028 GO:0005504 fatty acid binding 3/551 47/18639 0.0638297872340425 2.15920763022744 0.1615062199769 0.611083630393367 GO:0001848 complement binding 2/551 25/18639 0.08 2.70620689655172 0.167985497527734 0.629545650258699 GO:0042974 nuclear retinoic acid receptor binding 2/551 25/18639 0.08 2.70620689655172 0.167985497527734 0.629545650258699 GO:0042826 histone deacetylase binding 6/551 127/18639 0.047244094488189 1.59815367906598 0.174360149675894 0.647537732318331 GO:0003684 damaged DNA binding 4/551 74/18639 0.0540540540540541 1.82851817334576 0.175456809440072 0.647537732318331 GO:0048029 monosaccharide binding 4/551 74/18639 0.0540540540540541 1.82851817334576 0.175456809440072 0.647537732318331 GO:0016763 pentosyltransferase activity 3/551 49/18639 0.0612244897959184 2.07107670654469 0.176077604467755 0.647537732318331 GO:0070412 R-SMAD binding 2/551 26/18639 0.0769230769230769 2.60212201591512 0.178621686990794 0.650122684732959 GO:0120014 phospholipid transfer activity 2/551 26/18639 0.0769230769230769 2.60212201591512 0.178621686990794 0.650122684732959 GO:0008237 metallopeptidase activity 8/551 184/18639 0.0434782608695652 1.47076461769115 0.179258732639202 0.650122684732959 GO:0003725 double-stranded RNA binding 4/551 75/18639 0.0533333333333333 1.80413793103448 0.181340344372887 0.654655279914964 GO:0016791 phosphatase activity 11/551 273/18639 0.0402930402930403 1.36301629405078 0.186738970228426 0.671066527715852 GO:0005044 scavenger receptor activity 2/551 27/18639 0.0740740740740741 2.50574712643678 0.189357055363391 0.671279290860308 GO:0008266 poly(U) RNA binding 2/551 27/18639 0.0740740740740741 2.50574712643678 0.189357055363391 0.671279290860308 GO:0023026 MHC class II protein complex binding 2/551 27/18639 0.0740740740740741 2.50574712643678 0.189357055363391 0.671279290860308 GO:0005048 signal sequence binding 3/551 51/18639 0.0588235294117647 1.98985801217039 0.190995703271581 0.674052100783562 GO:0099106 ion channel regulator activity 7/551 160/18639 0.04375 1.47995689655172 0.196059015822053 0.686977215122829 GO:0005179 hormone activity 6/551 132/18639 0.0454545454545455 1.53761755485893 0.196614796050774 0.686977215122829 GO:0033218 amide binding 10/551 247/18639 0.0404858299595142 1.36953790311322 0.197276811458398 0.686977215122829 GO:0051393 alpha-actinin binding 2/551 28/18639 0.0714285714285714 2.41625615763547 0.200176480983511 0.694003923057371 GO:0033293 monocarboxylic acid binding 4/551 79/18639 0.0506329113924051 1.71278917503274 0.205494104831082 0.705623531349439 GO:0005246 calcium channel regulator activity 3/551 53/18639 0.0566037735849057 1.91476903057905 0.206217804587511 0.705623531349439 GO:0005544 calcium-dependent phospholipid binding 3/551 53/18639 0.0566037735849057 1.91476903057905 0.206217804587511 0.705623531349439 GO:0003785 actin monomer binding 2/551 29/18639 0.0689655172413793 2.33293697978597 0.211065646561449 0.711913566935208 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/551 29/18639 0.0689655172413793 2.33293697978597 0.211065646561449 0.711913566935208 GO:0097472 cyclin-dependent protein kinase activity 2/551 29/18639 0.0689655172413793 2.33293697978597 0.211065646561449 0.711913566935208 GO:0000049 tRNA binding 4/551 80/18639 0.05 1.69137931034483 0.211674427779973 0.711913566935208 GO:0002020 protease binding 6/551 136/18639 0.0441176470588235 1.49239350912779 0.215139445063676 0.720488269213246 GO:0016922 nuclear receptor binding 6/551 137/18639 0.0437956204379562 1.48150012584948 0.219862160144858 0.724990294276132 GO:0004620 phospholipase activity 5/551 109/18639 0.0458715596330275 1.55172413793103 0.220806923843662 0.724990294276132 GO:0140313 molecular sequestering activity 3/551 55/18639 0.0545454545454545 1.84514106583072 0.22170225163686 0.724990294276132 GO:0008106 alcohol dehydrogenase (NADP+) activity 2/551 30/18639 0.0666666666666667 2.2551724137931 0.222011004981636 0.724990294276132 GO:0008187 poly-pyrimidine tract binding 2/551 30/18639 0.0666666666666667 2.2551724137931 0.222011004981636 0.724990294276132 GO:0098918 structural constituent of synapse 2/551 30/18639 0.0666666666666667 2.2551724137931 0.222011004981636 0.724990294276132 GO:0030295 protein kinase activator activity 6/551 139/18639 0.0431654676258993 1.46018357727611 0.229410042648446 0.730376569387499 GO:0170055 lipid transmembrane transporter activity 3/551 56/18639 0.0535714285714286 1.8121921182266 0.229530170607451 0.730376569387499 GO:0016247 channel regulator activity 7/551 168/18639 0.0416666666666667 1.40948275862069 0.229927216276168 0.730376569387499 GO:0001540 amyloid-beta binding 4/551 83/18639 0.0481927710843374 1.63024511840465 0.23051422990596 0.730376569387499 GO:0047499 calcium-independent phospholipase A2 activity 2/551 31/18639 0.0645161290322581 2.18242491657397 0.23299974641757 0.730376569387499 GO:0016504 peptidase activator activity 3/551 57/18639 0.0526315789473684 1.78039927404719 0.237408622880175 0.730376569387499 GO:0141108 transporter regulator activity 7/551 170/18639 0.0411764705882353 1.39290060851927 0.238691558828094 0.730376569387499 GO:0003779 actin binding 16/551 443/18639 0.036117381489842 1.221763835915 0.24022616184892 0.730376569387499 GO:0042910 xenobiotic transmembrane transporter activity 2/551 32/18639 0.0625 2.11422413793103 0.244019766712313 0.730376569387499 GO:0047498 calcium-dependent phospholipase A2 activity 2/551 32/18639 0.0625 2.11422413793103 0.244019766712313 0.730376569387499 GO:0071813 lipoprotein particle binding 2/551 32/18639 0.0625 2.11422413793103 0.244019766712313 0.730376569387499 GO:0071814 protein-lipid complex binding 2/551 32/18639 0.0625 2.11422413793103 0.244019766712313 0.730376569387499 GO:0140142 nucleocytoplasmic carrier activity 2/551 32/18639 0.0625 2.11422413793103 0.244019766712313 0.730376569387499 GO:0001786 phosphatidylserine binding 3/551 59/18639 0.0508474576271186 1.72004675628288 0.253297878635158 0.730376569387499 GO:0070888 E-box binding 3/551 59/18639 0.0508474576271186 1.72004675628288 0.253297878635158 0.730376569387499 GO:0001221 transcription coregulator binding 5/551 115/18639 0.0434782608695652 1.47076461769115 0.253672990380012 0.730376569387499 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0004090 carbonyl reductase (NADPH) activity 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0004955 prostaglandin receptor activity 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0005522 profilin binding 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0016783 sulfurtransferase activity 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0032052 bile acid binding 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0032356 oxidized DNA binding 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0042975 peroxisome proliferator activated receptor binding 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0047429 nucleoside triphosphate diphosphatase activity 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0050815 phosphoserine residue binding 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0097177 mitochondrial ribosome binding 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0098505 G-rich strand telomeric DNA binding 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:1990757 ubiquitin ligase activator activity 1/551 10/18639 0.1 3.38275862068966 0.259291277306265 0.730376569387499 GO:0004252 serine-type endopeptidase activity 7/551 176/18639 0.0397727272727273 1.34541536050157 0.265597485845042 0.730376569387499 GO:0051427 hormone receptor binding 2/551 34/18639 0.0588235294117647 1.98985801217039 0.266108574374884 0.730376569387499 GO:0003727 single-stranded RNA binding 4/551 89/18639 0.0449438202247191 1.52034095311895 0.269306661003821 0.730376569387499 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 10/551 268/18639 0.0373134328358209 1.26222336592898 0.270800703929034 0.730376569387499 GO:0019209 kinase activator activity 6/551 148/18639 0.0405405405405405 1.37138863000932 0.273851318472847 0.730376569387499 GO:0005319 lipid transporter activity 7/551 178/18639 0.0393258426966292 1.33029833397908 0.274748893597217 0.730376569387499 GO:0004623 phospholipase A2 activity 2/551 35/18639 0.0571428571428571 1.93300492610837 0.277156414012772 0.730376569387499 GO:0051015 actin filament binding 8/551 209/18639 0.0382775119617225 1.29483583567068 0.278466507077236 0.730376569387499 GO:0003953 NAD+ nucleosidase activity 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0004954 prostanoid receptor activity 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0008046 axon guidance receptor activity 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0008199 ferric iron binding 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0008432 JUN kinase binding 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0008526 phosphatidylinositol transfer activity 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0015217 ADP transmembrane transporter activity 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0016594 glycine binding 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0019215 intermediate filament binding 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0019864 IgG binding 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0034056 estrogen response element binding 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0034511 U3 snoRNA binding 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0048185 activin binding 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0050786 RAGE receptor binding 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0050998 nitric-oxide synthase binding 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0140537 transcription regulator activator activity 1/551 11/18639 0.0909090909090909 3.07523510971787 0.281199619471934 0.730376569387499 GO:0004033 aldo-keto reductase (NADPH) activity 2/551 36/18639 0.0555555555555556 1.87931034482759 0.288193581957636 0.734681765598415 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/551 36/18639 0.0555555555555556 1.87931034482759 0.288193581957636 0.734681765598415 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/551 36/18639 0.0555555555555556 1.87931034482759 0.288193581957636 0.734681765598415 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/551 36/18639 0.0555555555555556 1.87931034482759 0.288193581957636 0.734681765598415 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/551 36/18639 0.0555555555555556 1.87931034482759 0.288193581957636 0.734681765598415 GO:0022829 wide pore channel activity 2/551 37/18639 0.0540540540540541 1.82851817334576 0.299211069279582 0.734681765598415 GO:0023023 MHC protein complex binding 2/551 37/18639 0.0540540540540541 1.82851817334576 0.299211069279582 0.734681765598415 GO:0003774 cytoskeletal motor activity 6/551 153/18639 0.0392156862745098 1.32657200811359 0.299379588116379 0.734681765598415 GO:0004032 aldose reductase (NADPH) activity 1/551 12/18639 0.0833333333333333 2.81896551724138 0.302461108073553 0.734681765598415 GO:0004300 enoyl-CoA hydratase activity 1/551 12/18639 0.0833333333333333 2.81896551724138 0.302461108073553 0.734681765598415 GO:0008179 adenylate cyclase binding 1/551 12/18639 0.0833333333333333 2.81896551724138 0.302461108073553 0.734681765598415 GO:0008603 cAMP-dependent protein kinase regulator activity 1/551 12/18639 0.0833333333333333 2.81896551724138 0.302461108073553 0.734681765598415 GO:0016208 AMP binding 1/551 12/18639 0.0833333333333333 2.81896551724138 0.302461108073553 0.734681765598415 GO:0031543 peptidyl-proline dioxygenase activity 1/551 12/18639 0.0833333333333333 2.81896551724138 0.302461108073553 0.734681765598415 GO:0043047 single-stranded telomeric DNA binding 1/551 12/18639 0.0833333333333333 2.81896551724138 0.302461108073553 0.734681765598415 GO:0045295 gamma-catenin binding 1/551 12/18639 0.0833333333333333 2.81896551724138 0.302461108073553 0.734681765598415 GO:0097677 STAT family protein binding 1/551 12/18639 0.0833333333333333 2.81896551724138 0.302461108073553 0.734681765598415 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/551 12/18639 0.0833333333333333 2.81896551724138 0.302461108073553 0.734681765598415 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/551 12/18639 0.0833333333333333 2.81896551724138 0.302461108073553 0.734681765598415 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/551 12/18639 0.0833333333333333 2.81896551724138 0.302461108073553 0.734681765598415 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/551 12/18639 0.0833333333333333 2.81896551724138 0.302461108073553 0.734681765598415 GO:0001217 DNA-binding transcription repressor activity 10/551 278/18639 0.0359712230215827 1.21681964773009 0.30848268533101 0.745728295171453 GO:0042393 histone binding 9/551 247/18639 0.0364372469635627 1.2325841128019 0.308903969791478 0.745728295171453 GO:0042162 telomeric DNA binding 2/551 38/18639 0.0526315789473684 1.78039927404719 0.310200407118189 0.746567952299738 GO:0030246 carbohydrate binding 10/551 280/18639 0.0357142857142857 1.20812807881773 0.316170942120861 0.750075557330195 GO:0050840 extracellular matrix binding 3/551 67/18639 0.0447761194029851 1.51466803911477 0.317957148008898 0.750075557330195 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/551 39/18639 0.0512820512820513 1.73474801061008 0.32115364272333 0.750075557330195 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/551 13/18639 0.0769230769230769 2.60212201591512 0.323094808049474 0.750075557330195 GO:0005172 vascular endothelial growth factor receptor binding 1/551 13/18639 0.0769230769230769 2.60212201591512 0.323094808049474 0.750075557330195 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/551 13/18639 0.0769230769230769 2.60212201591512 0.323094808049474 0.750075557330195 GO:0031432 titin binding 1/551 13/18639 0.0769230769230769 2.60212201591512 0.323094808049474 0.750075557330195 GO:0043560 insulin receptor substrate binding 1/551 13/18639 0.0769230769230769 2.60212201591512 0.323094808049474 0.750075557330195 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/551 13/18639 0.0769230769230769 2.60212201591512 0.323094808049474 0.750075557330195 GO:0045159 myosin II binding 1/551 13/18639 0.0769230769230769 2.60212201591512 0.323094808049474 0.750075557330195 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/551 13/18639 0.0769230769230769 2.60212201591512 0.323094808049474 0.750075557330195 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/551 13/18639 0.0769230769230769 2.60212201591512 0.323094808049474 0.750075557330195 GO:0005548 phospholipid transporter activity 3/551 68/18639 0.0441176470588235 1.49239350912779 0.326094171313673 0.754812096540767 GO:0042626 ATPase-coupled transmembrane transporter activity 4/551 98/18639 0.0408163265306122 1.38071780436312 0.329270106916335 0.755300086807745 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/551 40/18639 0.05 1.69137931034483 0.332063316436442 0.755300086807745 GO:0030331 nuclear estrogen receptor binding 2/551 40/18639 0.05 1.69137931034483 0.332063316436442 0.755300086807745 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/551 40/18639 0.05 1.69137931034483 0.332063316436442 0.755300086807745 GO:0050997 quaternary ammonium group binding 2/551 40/18639 0.05 1.69137931034483 0.332063316436442 0.755300086807745 GO:0140662 ATP-dependent protein folding chaperone 2/551 40/18639 0.05 1.69137931034483 0.332063316436442 0.755300086807745 GO:0016298 lipase activity 5/551 130/18639 0.0384615384615385 1.30106100795756 0.339918576573689 0.756097880527307 GO:0001530 lipopolysaccharide binding 2/551 41/18639 0.0487804878048781 1.65012615643398 0.342922439577701 0.756097880527307 GO:0005347 ATP transmembrane transporter activity 1/551 14/18639 0.0714285714285714 2.41625615763547 0.343119223423937 0.756097880527307 GO:0008559 ABC-type xenobiotic transporter activity 1/551 14/18639 0.0714285714285714 2.41625615763547 0.343119223423937 0.756097880527307 GO:0019763 immunoglobulin receptor activity 1/551 14/18639 0.0714285714285714 2.41625615763547 0.343119223423937 0.756097880527307 GO:0019992 diacylglycerol binding 1/551 14/18639 0.0714285714285714 2.41625615763547 0.343119223423937 0.756097880527307 GO:0032036 myosin heavy chain binding 1/551 14/18639 0.0714285714285714 2.41625615763547 0.343119223423937 0.756097880527307 GO:0034236 protein kinase A catalytic subunit binding 1/551 14/18639 0.0714285714285714 2.41625615763547 0.343119223423937 0.756097880527307 GO:0098847 sequence-specific single stranded DNA binding 1/551 14/18639 0.0714285714285714 2.41625615763547 0.343119223423937 0.756097880527307 GO:1901612 cardiolipin binding 1/551 14/18639 0.0714285714285714 2.41625615763547 0.343119223423937 0.756097880527307 GO:1990825 sequence-specific mRNA binding 1/551 14/18639 0.0714285714285714 2.41625615763547 0.343119223423937 0.756097880527307 GO:0008236 serine-type peptidase activity 7/551 194/18639 0.0360824742268041 1.22058300746534 0.35030727360655 0.756097880527307 GO:0140299 molecular sensor activity 3/551 71/18639 0.0422535211267606 1.42933462846042 0.350486152778136 0.756097880527307 GO:0016859 cis-trans isomerase activity 2/551 42/18639 0.0476190476190476 1.61083743842365 0.353724473205834 0.756097880527307 GO:0035198 miRNA binding 2/551 42/18639 0.0476190476190476 1.61083743842365 0.353724473205834 0.756097880527307 GO:0005518 collagen binding 3/551 72/18639 0.0416666666666667 1.40948275862069 0.358598865813377 0.756097880527307 GO:0015103 inorganic anion transmembrane transporter activity 6/551 165/18639 0.0363636363636364 1.23009404388715 0.362127374471656 0.756097880527307 GO:0000774 adenyl-nucleotide exchange factor activity 1/551 15/18639 0.0666666666666667 2.2551724137931 0.36255231378063 0.756097880527307 GO:0004089 carbonate dehydratase activity 1/551 15/18639 0.0666666666666667 2.2551724137931 0.36255231378063 0.756097880527307 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/551 15/18639 0.0666666666666667 2.2551724137931 0.36255231378063 0.756097880527307 GO:0004953 icosanoid receptor activity 1/551 15/18639 0.0666666666666667 2.2551724137931 0.36255231378063 0.756097880527307 GO:0008242 omega peptidase activity 1/551 15/18639 0.0666666666666667 2.2551724137931 0.36255231378063 0.756097880527307 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/551 15/18639 0.0666666666666667 2.2551724137931 0.36255231378063 0.756097880527307 GO:0015929 hexosaminidase activity 1/551 15/18639 0.0666666666666667 2.2551724137931 0.36255231378063 0.756097880527307 GO:0017081 chloride channel regulator activity 1/551 15/18639 0.0666666666666667 2.2551724137931 0.36255231378063 0.756097880527307 GO:0033130 acetylcholine receptor binding 1/551 15/18639 0.0666666666666667 2.2551724137931 0.36255231378063 0.756097880527307 GO:0050780 dopamine receptor binding 1/551 15/18639 0.0666666666666667 2.2551724137931 0.36255231378063 0.756097880527307 GO:0051371 muscle alpha-actinin binding 1/551 15/18639 0.0666666666666667 2.2551724137931 0.36255231378063 0.756097880527307 GO:0140161 monocarboxylate:sodium symporter activity 1/551 15/18639 0.0666666666666667 2.2551724137931 0.36255231378063 0.756097880527307 GO:0140776 protein-containing complex destabilizing activity 1/551 15/18639 0.0666666666666667 2.2551724137931 0.36255231378063 0.756097880527307 GO:0048156 tau protein binding 2/551 43/18639 0.0465116279069767 1.57337610264635 0.364463307718432 0.756097880527307 GO:0017171 serine hydrolase activity 7/551 198/18639 0.0353535353535354 1.19592476489028 0.369610574709315 0.756097880527307 GO:0000287 magnesium ion binding 8/551 230/18639 0.0347826086956522 1.17661169415292 0.370712604429608 0.756097880527307 GO:0003730 mRNA 3'-UTR binding 9/551 262/18639 0.0343511450381679 1.16201632008423 0.371095520315673 0.756097880527307 GO:0001046 core promoter sequence-specific DNA binding 2/551 44/18639 0.0454545454545455 1.53761755485893 0.375133243261791 0.756097880527307 GO:0001223 transcription coactivator binding 2/551 44/18639 0.0454545454545455 1.53761755485893 0.375133243261791 0.756097880527307 GO:0030547 signaling receptor inhibitor activity 2/551 44/18639 0.0454545454545455 1.53761755485893 0.375133243261791 0.756097880527307 GO:0044325 transmembrane transporter binding 5/551 136/18639 0.0367647058823529 1.24366125760649 0.375184128483308 0.756097880527307 GO:0140789 histone phosphatase activity 5/551 136/18639 0.0367647058823529 1.24366125760649 0.375184128483308 0.756097880527307 GO:0003688 DNA replication origin binding 1/551 16/18639 0.0625 2.11422413793103 0.381411510253292 0.756097880527307 GO:0004708 MAP kinase kinase activity 1/551 16/18639 0.0625 2.11422413793103 0.381411510253292 0.756097880527307 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/551 16/18639 0.0625 2.11422413793103 0.381411510253292 0.756097880527307 GO:0008142 oxysterol binding 1/551 16/18639 0.0625 2.11422413793103 0.381411510253292 0.756097880527307 GO:0015378 sodium:chloride symporter activity 1/551 16/18639 0.0625 2.11422413793103 0.381411510253292 0.756097880527307 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/551 16/18639 0.0625 2.11422413793103 0.381411510253292 0.756097880527307 GO:0016722 oxidoreductase activity, acting on metal ions 1/551 16/18639 0.0625 2.11422413793103 0.381411510253292 0.756097880527307 GO:0034450 ubiquitin-ubiquitin ligase activity 1/551 16/18639 0.0625 2.11422413793103 0.381411510253292 0.756097880527307 GO:0043023 ribosomal large subunit binding 1/551 16/18639 0.0625 2.11422413793103 0.381411510253292 0.756097880527307 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/551 16/18639 0.0625 2.11422413793103 0.381411510253292 0.756097880527307 GO:0097027 ubiquitin-protein transferase activator activity 1/551 16/18639 0.0625 2.11422413793103 0.381411510253292 0.756097880527307 GO:0140328 floppase activity 1/551 16/18639 0.0625 2.11422413793103 0.381411510253292 0.756097880527307 GO:0008009 chemokine activity 2/551 45/18639 0.0444444444444444 1.50344827586207 0.385728970920365 0.760823809810344 GO:0042605 peptide antigen binding 2/551 45/18639 0.0444444444444444 1.50344827586207 0.385728970920365 0.760823809810344 GO:0042578 phosphoric ester hydrolase activity 12/551 363/18639 0.0330578512396694 1.11826731262468 0.38778944513288 0.762975733298942 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/551 46/18639 0.0434782608695652 1.47076461769115 0.396245554656997 0.765388579889 GO:0030291 protein serine/threonine kinase inhibitor activity 2/551 46/18639 0.0434782608695652 1.47076461769115 0.396245554656997 0.765388579889 GO:0004550 nucleoside diphosphate kinase activity 1/551 17/18639 0.0588235294117647 1.98985801217039 0.399713731047495 0.765388579889 GO:0004659 prenyltransferase activity 1/551 17/18639 0.0588235294117647 1.98985801217039 0.399713731047495 0.765388579889 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/551 17/18639 0.0588235294117647 1.98985801217039 0.399713731047495 0.765388579889 GO:0005092 GDP-dissociation inhibitor activity 1/551 17/18639 0.0588235294117647 1.98985801217039 0.399713731047495 0.765388579889 GO:0019198 transmembrane receptor protein phosphatase activity 1/551 17/18639 0.0588235294117647 1.98985801217039 0.399713731047495 0.765388579889 GO:0030169 low-density lipoprotein particle binding 1/551 17/18639 0.0588235294117647 1.98985801217039 0.399713731047495 0.765388579889 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/551 17/18639 0.0588235294117647 1.98985801217039 0.399713731047495 0.765388579889 GO:0030548 acetylcholine receptor regulator activity 1/551 17/18639 0.0588235294117647 1.98985801217039 0.399713731047495 0.765388579889 GO:0036041 long-chain fatty acid binding 1/551 17/18639 0.0588235294117647 1.98985801217039 0.399713731047495 0.765388579889 GO:0140359 ABC-type transporter activity 2/551 47/18639 0.0425531914893617 1.43947175348496 0.406678413976112 0.776834737376699 GO:0004721 phosphoprotein phosphatase activity 6/551 175/18639 0.0342857142857143 1.15980295566502 0.414981740097088 0.78226937393157 GO:0000900 mRNA regulatory element binding translation repressor activity 1/551 18/18639 0.0555555555555556 1.87931034482759 0.417475396507318 0.78226937393157 GO:0015373 monoatomic anion:sodium symporter activity 1/551 18/18639 0.0555555555555556 1.87931034482759 0.417475396507318 0.78226937393157 GO:0016854 racemase and epimerase activity 1/551 18/18639 0.0555555555555556 1.87931034482759 0.417475396507318 0.78226937393157 GO:0034185 apolipoprotein binding 1/551 18/18639 0.0555555555555556 1.87931034482759 0.417475396507318 0.78226937393157 GO:0035615 clathrin adaptor activity 1/551 18/18639 0.0555555555555556 1.87931034482759 0.417475396507318 0.78226937393157 GO:0070064 proline-rich region binding 1/551 18/18639 0.0555555555555556 1.87931034482759 0.417475396507318 0.78226937393157 GO:0099602 neurotransmitter receptor regulator activity 1/551 18/18639 0.0555555555555556 1.87931034482759 0.417475396507318 0.78226937393157 GO:0004175 endopeptidase activity 13/551 405/18639 0.0320987654320988 1.08582375478927 0.420753266611475 0.782562881541903 GO:0033192 calmodulin-dependent protein phosphatase activity 3/551 81/18639 0.037037037037037 1.25287356321839 0.430605305836971 0.782562881541903 GO:0140791 histone H2AXS140 phosphatase activity 3/551 81/18639 0.037037037037037 1.25287356321839 0.430605305836971 0.782562881541903 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 3/551 81/18639 0.037037037037037 1.25287356321839 0.430605305836971 0.782562881541903 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 3/551 81/18639 0.037037037037037 1.25287356321839 0.430605305836971 0.782562881541903 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 3/551 81/18639 0.037037037037037 1.25287356321839 0.430605305836971 0.782562881541903 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 3/551 81/18639 0.037037037037037 1.25287356321839 0.430605305836971 0.782562881541903 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 3/551 81/18639 0.037037037037037 1.25287356321839 0.430605305836971 0.782562881541903 GO:1990439 MAP kinase serine/threonine phosphatase activity 3/551 81/18639 0.037037037037037 1.25287356321839 0.430605305836971 0.782562881541903 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/551 19/18639 0.0526315789473684 1.78039927404719 0.434712443740253 0.782562881541903 GO:0008574 plus-end-directed microtubule motor activity 1/551 19/18639 0.0526315789473684 1.78039927404719 0.434712443740253 0.782562881541903 GO:0015245 fatty acid transmembrane transporter activity 1/551 19/18639 0.0526315789473684 1.78039927404719 0.434712443740253 0.782562881541903 GO:0030506 ankyrin binding 1/551 19/18639 0.0526315789473684 1.78039927404719 0.434712443740253 0.782562881541903 GO:0043395 heparan sulfate proteoglycan binding 1/551 19/18639 0.0526315789473684 1.78039927404719 0.434712443740253 0.782562881541903 GO:0046624 sphingolipid transporter activity 1/551 19/18639 0.0526315789473684 1.78039927404719 0.434712443740253 0.782562881541903 GO:0050145 nucleoside monophosphate kinase activity 1/551 19/18639 0.0526315789473684 1.78039927404719 0.434712443740253 0.782562881541903 GO:0097001 ceramide binding 1/551 19/18639 0.0526315789473684 1.78039927404719 0.434712443740253 0.782562881541903 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 3/551 82/18639 0.0365853658536585 1.23759461732548 0.438443972337675 0.782562881541903 GO:0033549 MAP kinase phosphatase activity 3/551 82/18639 0.0365853658536585 1.23759461732548 0.438443972337675 0.782562881541903 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 3/551 83/18639 0.036144578313253 1.22268383880349 0.446241337678864 0.782562881541903 GO:0005254 chloride channel activity 3/551 83/18639 0.036144578313253 1.22268383880349 0.446241337678864 0.782562881541903 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 6/551 181/18639 0.0331491712707182 1.1213564488474 0.446508537360644 0.782562881541903 GO:0016830 carbon-carbon lyase activity 2/551 51/18639 0.0392156862745098 1.32657200811359 0.447492527809868 0.782562881541903 GO:0030544 Hsp70 protein binding 2/551 51/18639 0.0392156862745098 1.32657200811359 0.447492527809868 0.782562881541903 GO:0015294 solute:monoatomic cation symporter activity 4/551 116/18639 0.0344827586206897 1.16646848989298 0.449679230141631 0.782562881541903 GO:0000339 RNA cap binding 1/551 20/18639 0.05 1.69137931034483 0.451440340813245 0.782562881541903 GO:0001614 purinergic nucleotide receptor activity 1/551 20/18639 0.05 1.69137931034483 0.451440340813245 0.782562881541903 GO:0015095 magnesium ion transmembrane transporter activity 1/551 20/18639 0.05 1.69137931034483 0.451440340813245 0.782562881541903 GO:0016408 C-acyltransferase activity 1/551 20/18639 0.05 1.69137931034483 0.451440340813245 0.782562881541903 GO:0016502 nucleotide receptor activity 1/551 20/18639 0.05 1.69137931034483 0.451440340813245 0.782562881541903 GO:0042288 MHC class I protein binding 1/551 20/18639 0.05 1.69137931034483 0.451440340813245 0.782562881541903 GO:0043024 ribosomal small subunit binding 1/551 20/18639 0.05 1.69137931034483 0.451440340813245 0.782562881541903 GO:0052745 inositol phosphate phosphatase activity 1/551 20/18639 0.05 1.69137931034483 0.451440340813245 0.782562881541903 GO:0140664 ATP-dependent DNA damage sensor activity 1/551 20/18639 0.05 1.69137931034483 0.451440340813245 0.782562881541903 GO:0004860 protein kinase inhibitor activity 3/551 84/18639 0.0357142857142857 1.20812807881773 0.453995271230904 0.783540084339301 GO:0017018 myosin phosphatase activity 3/551 84/18639 0.0357142857142857 1.20812807881773 0.453995271230904 0.783540084339301 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 2/551 52/18639 0.0384615384615385 1.30106100795756 0.45744937355518 0.787773866494368 GO:0051018 protein kinase A binding 2/551 53/18639 0.0377358490566038 1.2765126870527 0.467301591946069 0.793231717928964 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/551 21/18639 0.0476190476190476 1.61083743842365 0.467674100532452 0.793231717928964 GO:0035613 RNA stem-loop binding 1/551 21/18639 0.0476190476190476 1.61083743842365 0.467674100532452 0.793231717928964 GO:0051010 microtubule plus-end binding 1/551 21/18639 0.0476190476190476 1.61083743842365 0.467674100532452 0.793231717928964 GO:0061891 calcium ion sensor activity 1/551 21/18639 0.0476190476190476 1.61083743842365 0.467674100532452 0.793231717928964 GO:0140312 cargo adaptor activity 1/551 21/18639 0.0476190476190476 1.61083743842365 0.467674100532452 0.793231717928964 GO:1904047 S-adenosyl-L-methionine binding 1/551 21/18639 0.0476190476190476 1.61083743842365 0.467674100532452 0.793231717928964 GO:0050660 flavin adenine dinucleotide binding 3/551 86/18639 0.0348837209302326 1.18003207698476 0.469364788954115 0.794387287971804 GO:0050661 NADP binding 2/551 54/18639 0.037037037037037 1.25287356321839 0.477046661172257 0.803930882960528 GO:0140463 chromatin-protein adaptor activity 2/551 54/18639 0.037037037037037 1.25287356321839 0.477046661172257 0.803930882960528 GO:0015108 chloride transmembrane transporter activity 4/551 121/18639 0.0330578512396694 1.11826731262468 0.482110714633851 0.804040982326362 GO:0015377 chloride:monoatomic cation symporter activity 1/551 22/18639 0.0454545454545455 1.53761755485893 0.483428293818874 0.804040982326362 GO:0016881 acid-amino acid ligase activity 1/551 22/18639 0.0454545454545455 1.53761755485893 0.483428293818874 0.804040982326362 GO:0031683 G-protein beta/gamma-subunit complex binding 1/551 22/18639 0.0454545454545455 1.53761755485893 0.483428293818874 0.804040982326362 GO:0061133 endopeptidase activator activity 1/551 22/18639 0.0454545454545455 1.53761755485893 0.483428293818874 0.804040982326362 GO:0140784 metal ion sensor activity 1/551 22/18639 0.0454545454545455 1.53761755485893 0.483428293818874 0.804040982326362 GO:0003713 transcription coactivator activity 8/551 256/18639 0.03125 1.05711206896552 0.487059259990944 0.804040982326362 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 3/551 89/18639 0.0337078651685393 1.14025571483921 0.492045377191728 0.804040982326362 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 3/551 89/18639 0.0337078651685393 1.14025571483921 0.492045377191728 0.804040982326362 GO:0003712 transcription coregulator activity 15/551 495/18639 0.0303030303030303 1.02507836990596 0.498199815952224 0.804040982326362 GO:0000295 adenine nucleotide transmembrane transporter activity 1/551 23/18639 0.0434782608695652 1.47076461769115 0.498717062691722 0.804040982326362 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/551 23/18639 0.0434782608695652 1.47076461769115 0.498717062691722 0.804040982326362 GO:0005212 structural constituent of eye lens 1/551 23/18639 0.0434782608695652 1.47076461769115 0.498717062691722 0.804040982326362 GO:0005283 amino acid:sodium symporter activity 1/551 23/18639 0.0434782608695652 1.47076461769115 0.498717062691722 0.804040982326362 GO:0016493 C-C chemokine receptor activity 1/551 23/18639 0.0434782608695652 1.47076461769115 0.498717062691722 0.804040982326362 GO:0043274 phospholipase binding 1/551 23/18639 0.0434782608695652 1.47076461769115 0.498717062691722 0.804040982326362 GO:0070577 lysine-acetylated histone binding 1/551 23/18639 0.0434782608695652 1.47076461769115 0.498717062691722 0.804040982326362 GO:0019210 kinase inhibitor activity 3/551 90/18639 0.0333333333333333 1.12758620689655 0.49949912264914 0.804040982326362 GO:0140793 histone H2AXY142 phosphatase activity 3/551 90/18639 0.0333333333333333 1.12758620689655 0.49949912264914 0.804040982326362 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/551 24/18639 0.0416666666666667 1.40948275862069 0.513554132870969 0.804040982326362 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/551 24/18639 0.0416666666666667 1.40948275862069 0.513554132870969 0.804040982326362 GO:0004622 lysophospholipase activity 1/551 24/18639 0.0416666666666667 1.40948275862069 0.513554132870969 0.804040982326362 GO:0005315 phosphate transmembrane transporter activity 1/551 24/18639 0.0416666666666667 1.40948275862069 0.513554132870969 0.804040982326362 GO:0015149 hexose transmembrane transporter activity 1/551 24/18639 0.0416666666666667 1.40948275862069 0.513554132870969 0.804040982326362 GO:0019957 C-C chemokine binding 1/551 24/18639 0.0416666666666667 1.40948275862069 0.513554132870969 0.804040982326362 GO:0035035 histone acetyltransferase binding 1/551 24/18639 0.0416666666666667 1.40948275862069 0.513554132870969 0.804040982326362 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/551 24/18639 0.0416666666666667 1.40948275862069 0.513554132870969 0.804040982326362 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/551 24/18639 0.0416666666666667 1.40948275862069 0.513554132870969 0.804040982326362 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/551 24/18639 0.0416666666666667 1.40948275862069 0.513554132870969 0.804040982326362 GO:0050699 WW domain binding 1/551 24/18639 0.0416666666666667 1.40948275862069 0.513554132870969 0.804040982326362 GO:0055056 D-glucose transmembrane transporter activity 1/551 24/18639 0.0416666666666667 1.40948275862069 0.513554132870969 0.804040982326362 GO:0070300 phosphatidic acid binding 1/551 24/18639 0.0416666666666667 1.40948275862069 0.513554132870969 0.804040982326362 GO:0070840 dynein complex binding 1/551 24/18639 0.0416666666666667 1.40948275862069 0.513554132870969 0.804040982326362 GO:0140033 acetylation-dependent protein binding 1/551 24/18639 0.0416666666666667 1.40948275862069 0.513554132870969 0.804040982326362 GO:0140612 DNA damage sensor activity 1/551 24/18639 0.0416666666666667 1.40948275862069 0.513554132870969 0.804040982326362 GO:0017116 single-stranded DNA helicase activity 2/551 58/18639 0.0344827586206897 1.16646848989298 0.514913157677873 0.804040982326362 GO:0061980 regulatory RNA binding 2/551 58/18639 0.0344827586206897 1.16646848989298 0.514913157677873 0.804040982326362 GO:0001664 G protein-coupled receptor binding 9/551 297/18639 0.0303030303030303 1.02507836990596 0.517405013222741 0.80633216912138 GO:0004879 nuclear receptor activity 2/551 59/18639 0.0338983050847458 1.14669783752192 0.524092641153056 0.811930922416251 GO:0045309 protein phosphorylated amino acid binding 2/551 59/18639 0.0338983050847458 1.14669783752192 0.524092641153056 0.811930922416251 GO:0070063 RNA polymerase binding 2/551 59/18639 0.0338983050847458 1.14669783752192 0.524092641153056 0.811930922416251 GO:0005537 D-mannose binding 1/551 25/18639 0.04 1.35310344827586 0.52795282601027 0.812438903020712 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/551 25/18639 0.04 1.35310344827586 0.52795282601027 0.812438903020712 GO:0120020 cholesterol transfer activity 1/551 25/18639 0.04 1.35310344827586 0.52795282601027 0.812438903020712 GO:0098531 ligand-modulated transcription factor activity 2/551 60/18639 0.0333333333333333 1.12758620689655 0.533154480659682 0.812438903020712 GO:0001637 G protein-coupled chemoattractant receptor activity 1/551 26/18639 0.0384615384615385 1.30106100795756 0.541926071571049 0.812438903020712 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/551 26/18639 0.0384615384615385 1.30106100795756 0.541926071571049 0.812438903020712 GO:0004950 chemokine receptor activity 1/551 26/18639 0.0384615384615385 1.30106100795756 0.541926071571049 0.812438903020712 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/551 26/18639 0.0384615384615385 1.30106100795756 0.541926071571049 0.812438903020712 GO:0015145 monosaccharide transmembrane transporter activity 1/551 26/18639 0.0384615384615385 1.30106100795756 0.541926071571049 0.812438903020712 GO:0015216 purine nucleotide transmembrane transporter activity 1/551 26/18639 0.0384615384615385 1.30106100795756 0.541926071571049 0.812438903020712 GO:0019865 immunoglobulin binding 1/551 26/18639 0.0384615384615385 1.30106100795756 0.541926071571049 0.812438903020712 GO:0030247 polysaccharide binding 1/551 26/18639 0.0384615384615385 1.30106100795756 0.541926071571049 0.812438903020712 GO:0034237 protein kinase A regulatory subunit binding 1/551 26/18639 0.0384615384615385 1.30106100795756 0.541926071571049 0.812438903020712 GO:0050681 nuclear androgen receptor binding 1/551 26/18639 0.0384615384615385 1.30106100795756 0.541926071571049 0.812438903020712 GO:0070006 metalloaminopeptidase activity 1/551 26/18639 0.0384615384615385 1.30106100795756 0.541926071571049 0.812438903020712 GO:0097602 cullin family protein binding 1/551 26/18639 0.0384615384615385 1.30106100795756 0.541926071571049 0.812438903020712 GO:0019905 syntaxin binding 2/551 61/18639 0.0327868852459016 1.10910118711136 0.542097599397046 0.812438903020712 GO:0004896 cytokine receptor activity 3/551 96/18639 0.03125 1.05711206896552 0.543002367203169 0.812438903020712 GO:0008395 steroid hydroxylase activity 1/551 27/18639 0.037037037037037 1.25287356321839 0.555486418348267 0.82640418003797 GO:0035255 ionotropic glutamate receptor binding 1/551 27/18639 0.037037037037037 1.25287356321839 0.555486418348267 0.82640418003797 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/551 27/18639 0.037037037037037 1.25287356321839 0.555486418348267 0.82640418003797 GO:0004725 protein tyrosine phosphatase activity 3/551 98/18639 0.0306122448979592 1.03553835327234 0.557009809790772 0.827107019444033 GO:0003714 transcription corepressor activity 6/551 204/18639 0.0294117647058824 0.994929006085193 0.56258898685867 0.83381832892236 GO:0046625 sphingolipid binding 1/551 28/18639 0.0357142857142857 1.20812807881773 0.568646045658073 0.838060745192703 GO:0046966 nuclear thyroid hormone receptor binding 1/551 28/18639 0.0357142857142857 1.20812807881773 0.568646045658073 0.838060745192703 GO:0051119 sugar transmembrane transporter activity 1/551 28/18639 0.0357142857142857 1.20812807881773 0.568646045658073 0.838060745192703 GO:0043130 ubiquitin binding 3/551 100/18639 0.03 1.0148275862069 0.570756899820297 0.839599402165559 GO:0120013 lipid transfer activity 2/551 65/18639 0.0307692307692308 1.04084880636605 0.576666959877627 0.846710629521815 GO:0004629 phospholipase C activity 1/551 29/18639 0.0344827586206897 1.16646848989298 0.581416774197238 0.850511154820123 GO:0005416 amino acid:monoatomic cation symporter activity 1/551 29/18639 0.0344827586206897 1.16646848989298 0.581416774197238 0.850511154820123 GO:0008238 exopeptidase activity 3/551 102/18639 0.0294117647058824 0.994929006085193 0.58423715014334 0.852490698667072 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 10/551 349/18639 0.0286532951289398 0.969271811085861 0.58493643872963 0.852490698667072 GO:0051020 GTPase binding 9/551 315/18639 0.0285714285714286 0.966502463054187 0.588584506158083 0.854348318595236 GO:0004722 protein serine/threonine phosphatase activity 3/551 103/18639 0.029126213592233 0.985269501171744 0.590875459724881 0.854348318595236 GO:0005253 monoatomic anion channel activity 3/551 103/18639 0.029126213592233 0.985269501171744 0.590875459724881 0.854348318595236 GO:0001965 G-protein alpha-subunit binding 1/551 30/18639 0.0333333333333333 1.12758620689655 0.593810076583983 0.854348318595236 GO:0015215 nucleotide transmembrane transporter activity 1/551 30/18639 0.0333333333333333 1.12758620689655 0.593810076583983 0.854348318595236 GO:0016769 transferase activity, transferring nitrogenous groups 1/551 30/18639 0.0333333333333333 1.12758620689655 0.593810076583983 0.854348318595236 GO:0031210 phosphatidylcholine binding 1/551 30/18639 0.0333333333333333 1.12758620689655 0.593810076583983 0.854348318595236 GO:0005164 tumor necrosis factor receptor binding 1/551 31/18639 0.032258064516129 1.09121245828699 0.605837087589529 0.863756862197391 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/551 31/18639 0.032258064516129 1.09121245828699 0.605837087589529 0.863756862197391 GO:0005452 solute:inorganic anion antiporter activity 1/551 31/18639 0.032258064516129 1.09121245828699 0.605837087589529 0.863756862197391 GO:0017147 Wnt-protein binding 1/551 31/18639 0.032258064516129 1.09121245828699 0.605837087589529 0.863756862197391 GO:0072349 modified amino acid transmembrane transporter activity 1/551 31/18639 0.032258064516129 1.09121245828699 0.605837087589529 0.863756862197391 GO:0000149 SNARE binding 3/551 106/18639 0.0283018867924528 0.957384515289525 0.610376152685034 0.867086700655454 GO:0004497 monooxygenase activity 3/551 106/18639 0.0283018867924528 0.957384515289525 0.610376152685034 0.867086700655454 GO:0016782 transferase activity, transferring sulphur-containing groups 2/551 70/18639 0.0285714285714286 0.966502463054187 0.617141096184731 0.869372592616546 GO:0030515 snoRNA binding 1/551 32/18639 0.03125 1.05711206896552 0.61750861406944 0.869372592616546 GO:0043425 bHLH transcription factor binding 1/551 32/18639 0.03125 1.05711206896552 0.61750861406944 0.869372592616546 GO:0051059 NF-kappaB binding 1/551 32/18639 0.03125 1.05711206896552 0.61750861406944 0.869372592616546 GO:0120015 sterol transfer activity 1/551 32/18639 0.03125 1.05711206896552 0.61750861406944 0.869372592616546 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/551 33/18639 0.0303030303030303 1.02507836990596 0.628835144603526 0.879028878868517 GO:0019956 chemokine binding 1/551 33/18639 0.0303030303030303 1.02507836990596 0.628835144603526 0.879028878868517 GO:0030296 protein tyrosine kinase activator activity 1/551 33/18639 0.0303030303030303 1.02507836990596 0.628835144603526 0.879028878868517 GO:0140311 protein sequestering activity 1/551 33/18639 0.0303030303030303 1.02507836990596 0.628835144603526 0.879028878868517 GO:0015293 symporter activity 4/551 146/18639 0.0273972602739726 0.92678318375059 0.630171046970796 0.87933442192556 GO:0042379 chemokine receptor binding 2/551 72/18639 0.0277777777777778 0.939655172413793 0.632477978098146 0.88099144913848 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/551 34/18639 0.0294117647058824 0.994929006085193 0.639826858852879 0.884962632543437 GO:0016831 carboxy-lyase activity 1/551 34/18639 0.0294117647058824 0.994929006085193 0.639826858852879 0.884962632543437 GO:0030332 cyclin binding 1/551 34/18639 0.0294117647058824 0.994929006085193 0.639826858852879 0.884962632543437 GO:0090482 vitamin transmembrane transporter activity 1/551 34/18639 0.0294117647058824 0.994929006085193 0.639826858852879 0.884962632543437 GO:0008509 monoatomic anion transmembrane transporter activity 4/551 149/18639 0.0268456375838926 0.90812311964823 0.646013727264505 0.89179614313621 GO:0003678 DNA helicase activity 2/551 74/18639 0.027027027027027 0.91425908667288 0.647331072267323 0.89179614313621 GO:0005154 epidermal growth factor receptor binding 1/551 35/18639 0.0285714285714286 0.966502463054187 0.650493636642294 0.89179614313621 GO:0005343 organic acid:sodium symporter activity 1/551 35/18639 0.0285714285714286 0.966502463054187 0.650493636642294 0.89179614313621 GO:0140566 histone reader activity 1/551 35/18639 0.0285714285714286 0.966502463054187 0.650493636642294 0.89179614313621 GO:0008234 cysteine-type peptidase activity 5/551 187/18639 0.0267379679144385 0.904480914622902 0.651566432405744 0.89179614313621 GO:0005484 SNAP receptor activity 1/551 36/18639 0.0277777777777778 0.939655172413793 0.660845066776141 0.90136060234458 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/551 36/18639 0.0277777777777778 0.939655172413793 0.660845066776141 0.90136060234458 GO:0017124 SH3 domain binding 3/551 115/18639 0.0260869565217391 0.882458770614693 0.665061173913775 0.902419213569208 GO:0035401 histone H3Y41 kinase activity 3/551 115/18639 0.0260869565217391 0.882458770614693 0.665061173913775 0.902419213569208 GO:0140801 histone H2AXY142 kinase activity 3/551 115/18639 0.0260869565217391 0.882458770614693 0.665061173913775 0.902419213569208 GO:0051540 metal cluster binding 2/551 77/18639 0.025974025974026 0.878638602776534 0.668713155366459 0.905812828353533 GO:0030280 structural constituent of skin epidermis 1/551 37/18639 0.027027027027027 0.91425908667288 0.67089045559549 0.907200667617956 GO:0004386 helicase activity 4/551 155/18639 0.0258064516129032 0.872969966629588 0.676332197299999 0.910202297994602 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 13/551 484/18639 0.0268595041322314 0.908592191507552 0.677269525663048 0.910202297994602 GO:0000146 microfilament motor activity 1/551 38/18639 0.0263157894736842 0.890199637023594 0.680638835284066 0.910202297994602 GO:0005109 frizzled binding 1/551 38/18639 0.0263157894736842 0.890199637023594 0.680638835284066 0.910202297994602 GO:0005501 retinoid binding 1/551 38/18639 0.0263157894736842 0.890199637023594 0.680638835284066 0.910202297994602 GO:0019840 isoprenoid binding 1/551 38/18639 0.0263157894736842 0.890199637023594 0.680638835284066 0.910202297994602 GO:0140375 immune receptor activity 4/551 156/18639 0.0256410256410256 0.86737400530504 0.681206040049327 0.910202297994602 GO:0008514 organic anion transmembrane transporter activity 7/551 269/18639 0.0260223048327138 0.880271760030765 0.686112155744108 0.915203841645106 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/551 39/18639 0.0256410256410256 0.86737400530504 0.690098971930401 0.917221444715108 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/551 39/18639 0.0256410256410256 0.86737400530504 0.690098971930401 0.917221444715108 GO:0016887 ATP hydrolysis activity 11/551 417/18639 0.026378896882494 0.892334408335401 0.692180779361646 0.917221444715108 GO:0032182 ubiquitin-like protein binding 3/551 120/18639 0.025 0.845689655172414 0.69293424621796 0.917221444715108 GO:0001216 DNA-binding transcription activator activity 13/551 491/18639 0.0264765784114053 0.895638738675469 0.696739325522653 0.917221444715108 GO:0004177 aminopeptidase activity 1/551 40/18639 0.025 0.845689655172414 0.699279373353322 0.917221444715108 GO:0015144 carbohydrate transmembrane transporter activity 1/551 40/18639 0.025 0.845689655172414 0.699279373353322 0.917221444715108 GO:0061791 GTPase motor activity 1/551 40/18639 0.025 0.845689655172414 0.699279373353322 0.917221444715108 GO:0071855 neuropeptide receptor binding 1/551 40/18639 0.025 0.845689655172414 0.699279373353322 0.917221444715108 GO:1990606 membrane scission GTPase motor activity 1/551 40/18639 0.025 0.845689655172414 0.699279373353322 0.917221444715108 GO:0005126 cytokine receptor binding 7/551 275/18639 0.0254545454545455 0.861065830721003 0.70782342455895 0.924285554728193 GO:0042169 SH2 domain binding 1/551 41/18639 0.024390243902439 0.825063078216989 0.708188296697713 0.924285554728193 GO:0042287 MHC protein binding 1/551 41/18639 0.024390243902439 0.825063078216989 0.708188296697713 0.924285554728193 GO:0008083 growth factor activity 4/551 162/18639 0.0246913580246914 0.835249042145594 0.709366181837272 0.924290041566115 GO:0051117 ATPase binding 2/551 84/18639 0.0238095238095238 0.805418719211823 0.714524544935033 0.929403897562311 GO:0004520 DNA endonuclease activity 1/551 42/18639 0.0238095238095238 0.805418719211823 0.716833755807271 0.929403897562311 GO:0051879 Hsp90 protein binding 1/551 42/18639 0.0238095238095238 0.805418719211823 0.716833755807271 0.929403897562311 GO:0019783 ubiquitin-like protein peptidase activity 3/551 127/18639 0.0236220472440945 0.799076839532989 0.728967133023392 0.943434549903529 GO:0008081 phosphoric diester hydrolase activity 2/551 87/18639 0.0229885057471264 0.777645659928656 0.732472262973256 0.943434549903529 GO:0004197 cysteine-type endopeptidase activity 2/551 88/18639 0.0227272727272727 0.768808777429467 0.738238191633596 0.943434549903529 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/551 45/18639 0.0222222222222222 0.751724137931034 0.741265985463878 0.943434549903529 GO:0140303 intramembrane lipid transporter activity 1/551 45/18639 0.0222222222222222 0.751724137931034 0.741265985463878 0.943434549903529 GO:0008094 ATP-dependent activity, acting on DNA 5/551 210/18639 0.0238095238095238 0.805418719211823 0.747489376646693 0.943434549903529 GO:0031072 heat shock protein binding 3/551 131/18639 0.0229007633587786 0.774677546722822 0.748022288982087 0.943434549903529 GO:0015291 secondary active transmembrane transporter activity 7/551 287/18639 0.024390243902439 0.825063078216989 0.748180949910566 0.943434549903529 GO:0001784 phosphotyrosine residue binding 1/551 47/18639 0.0212765957446809 0.71973587674248 0.756373425543526 0.943434549903529 GO:0043495 protein-membrane adaptor activity 1/551 47/18639 0.0212765957446809 0.71973587674248 0.756373425543526 0.943434549903529 GO:0061749 forked DNA-dependent helicase activity 1/551 47/18639 0.0212765957446809 0.71973587674248 0.756373425543526 0.943434549903529 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/551 47/18639 0.0212765957446809 0.71973587674248 0.756373425543526 0.943434549903529 GO:0052689 carboxylic ester hydrolase activity 2/551 92/18639 0.0217391304347826 0.735382308845577 0.760251108107092 0.943434549903529 GO:0009378 four-way junction helicase activity 1/551 48/18639 0.0208333333333333 0.704741379310345 0.763593640825665 0.943434549903529 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/551 48/18639 0.0208333333333333 0.704741379310345 0.763593640825665 0.943434549903529 GO:0036121 double-stranded DNA helicase activity 1/551 48/18639 0.0208333333333333 0.704741379310345 0.763593640825665 0.943434549903529 GO:0043138 3'-5' DNA helicase activity 1/551 48/18639 0.0208333333333333 0.704741379310345 0.763593640825665 0.943434549903529 GO:0140693 molecular condensate scaffold activity 1/551 48/18639 0.0208333333333333 0.704741379310345 0.763593640825665 0.943434549903529 GO:0051219 phosphoprotein binding 2/551 93/18639 0.021505376344086 0.727474972191324 0.765497948562509 0.943434549903529 GO:0003924 GTPase activity 8/551 331/18639 0.0241691842900302 0.817585165121367 0.766167670851545 0.943434549903529 GO:0001222 transcription corepressor binding 1/551 49/18639 0.0204081632653061 0.690358902181562 0.770600251761336 0.943434549903529 GO:0005004 GPI-linked ephrin receptor activity 1/551 49/18639 0.0204081632653061 0.690358902181562 0.770600251761336 0.943434549903529 GO:0005008 hepatocyte growth factor receptor activity 1/551 49/18639 0.0204081632653061 0.690358902181562 0.770600251761336 0.943434549903529 GO:0005009 insulin receptor activity 1/551 49/18639 0.0204081632653061 0.690358902181562 0.770600251761336 0.943434549903529 GO:0005011 macrophage colony-stimulating factor receptor activity 1/551 49/18639 0.0204081632653061 0.690358902181562 0.770600251761336 0.943434549903529 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/551 49/18639 0.0204081632653061 0.690358902181562 0.770600251761336 0.943434549903529 GO:0005020 stem cell factor receptor activity 1/551 49/18639 0.0204081632653061 0.690358902181562 0.770600251761336 0.943434549903529 GO:0008288 boss receptor activity 1/551 49/18639 0.0204081632653061 0.690358902181562 0.770600251761336 0.943434549903529 GO:0035254 glutamate receptor binding 1/551 49/18639 0.0204081632653061 0.690358902181562 0.770600251761336 0.943434549903529 GO:0036332 placental growth factor receptor activity 1/551 49/18639 0.0204081632653061 0.690358902181562 0.770600251761336 0.943434549903529 GO:0038062 protein tyrosine kinase collagen receptor activity 1/551 49/18639 0.0204081632653061 0.690358902181562 0.770600251761336 0.943434549903529 GO:0060175 brain-derived neurotrophic factor receptor activity 1/551 49/18639 0.0204081632653061 0.690358902181562 0.770600251761336 0.943434549903529 GO:0060590 ATPase regulator activity 1/551 49/18639 0.0204081632653061 0.690358902181562 0.770600251761336 0.943434549903529 GO:0042562 hormone binding 2/551 94/18639 0.0212765957446809 0.71973587674248 0.770644814319265 0.943434549903529 GO:0005006 epidermal growth factor receptor activity 1/551 50/18639 0.02 0.676551724137931 0.777399566515478 0.943434549903529 GO:0005007 fibroblast growth factor receptor activity 1/551 50/18639 0.02 0.676551724137931 0.777399566515478 0.943434549903529 GO:0005017 platelet-derived growth factor receptor activity 1/551 50/18639 0.02 0.676551724137931 0.777399566515478 0.943434549903529 GO:0005019 platelet-derived growth factor beta-receptor activity 1/551 50/18639 0.02 0.676551724137931 0.777399566515478 0.943434549903529 GO:0015605 organophosphate ester transmembrane transporter activity 1/551 50/18639 0.02 0.676551724137931 0.777399566515478 0.943434549903529 GO:0032813 tumor necrosis factor receptor superfamily binding 1/551 50/18639 0.02 0.676551724137931 0.777399566515478 0.943434549903529 GO:0048020 CCR chemokine receptor binding 1/551 50/18639 0.02 0.676551724137931 0.777399566515478 0.943434549903529 GO:0140097 catalytic activity, acting on DNA 8/551 336/18639 0.0238095238095238 0.805418719211823 0.780138285481492 0.943434549903529 GO:0070851 growth factor receptor binding 3/551 139/18639 0.0215827338129496 0.730091788638055 0.782905683283693 0.943434549903529 GO:0005010 insulin-like growth factor receptor activity 1/551 51/18639 0.0196078431372549 0.663286004056795 0.783997707289591 0.943434549903529 GO:0005021 vascular endothelial growth factor receptor activity 1/551 51/18639 0.0196078431372549 0.663286004056795 0.783997707289591 0.943434549903529 GO:0005030 neurotrophin receptor activity 1/551 51/18639 0.0196078431372549 0.663286004056795 0.783997707289591 0.943434549903529 GO:0016597 amino acid binding 1/551 51/18639 0.0196078431372549 0.663286004056795 0.783997707289591 0.943434549903529 GO:0004713 protein tyrosine kinase activity 3/551 140/18639 0.0214285714285714 0.72487684729064 0.786973183453258 0.945569305920174 GO:0005525 GTP binding 9/551 378/18639 0.0238095238095238 0.805418719211823 0.789887698674746 0.947032120977509 GO:0005003 ephrin receptor activity 1/551 53/18639 0.0188679245283019 0.63825634352635 0.796614058560496 0.947032120977509 GO:0005005 transmembrane-ephrin receptor activity 1/551 53/18639 0.0188679245283019 0.63825634352635 0.796614058560496 0.947032120977509 GO:0008146 sulfotransferase activity 1/551 53/18639 0.0188679245283019 0.63825634352635 0.796614058560496 0.947032120977509 GO:0017046 peptide hormone binding 1/551 53/18639 0.0188679245283019 0.63825634352635 0.796614058560496 0.947032120977509 GO:0038064 collagen receptor activity 1/551 53/18639 0.0188679245283019 0.63825634352635 0.796614058560496 0.947032120977509 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/551 53/18639 0.0188679245283019 0.63825634352635 0.796614058560496 0.947032120977509 GO:0015485 cholesterol binding 1/551 54/18639 0.0185185185185185 0.626436781609195 0.802643632096124 0.951326112138026 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/551 54/18639 0.0185185185185185 0.626436781609195 0.802643632096124 0.951326112138026 GO:0008374 O-acyltransferase activity 1/551 55/18639 0.0181818181818182 0.615047021943574 0.808494767889238 0.956820123802753 GO:0046943 carboxylic acid transmembrane transporter activity 4/551 188/18639 0.0212765957446809 0.71973587674248 0.810381346608226 0.957612792463475 GO:0005342 organic acid transmembrane transporter activity 4/551 189/18639 0.0211640211640212 0.715927750410509 0.813616646904842 0.959994454443944 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/551 57/18639 0.0175438596491228 0.593466424682396 0.819682656103748 0.965703967595284 GO:0015459 potassium channel regulator activity 1/551 59/18639 0.0169491525423729 0.573348918760959 0.830218055758713 0.975196432659862 GO:0036002 pre-mRNA binding 1/551 59/18639 0.0169491525423729 0.573348918760959 0.830218055758713 0.975196432659862 GO:0005496 steroid binding 2/551 108/18639 0.0185185185185185 0.626436781609195 0.832949928843568 0.975288035423409 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/551 60/18639 0.0166666666666667 0.563793103448276 0.835253031607849 0.975288035423409 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/551 60/18639 0.0166666666666667 0.563793103448276 0.835253031607849 0.975288035423409 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/551 60/18639 0.0166666666666667 0.563793103448276 0.835253031607849 0.975288035423409 GO:0019001 guanyl nucleotide binding 9/551 400/18639 0.0225 0.761120689655172 0.83996674736207 0.97664602357638 GO:0032561 guanyl ribonucleotide binding 9/551 400/18639 0.0225 0.761120689655172 0.83996674736207 0.97664602357638 GO:0015026 coreceptor activity 1/551 61/18639 0.0163934426229508 0.554550593555681 0.84013895547803 0.97664602357638 GO:0031267 small GTPase binding 6/551 283/18639 0.0212014134275618 0.717192640428902 0.846054730254 0.982072378628168 GO:1901682 sulfur compound transmembrane transporter activity 1/551 63/18639 0.0158730158730159 0.536945812807882 0.84948113593849 0.984597428547263 GO:0004536 DNA nuclease activity 1/551 64/18639 0.015625 0.528556034482759 0.853945815853321 0.988316701583182 GO:0101005 deubiquitinase activity 2/551 115/18639 0.0173913043478261 0.588305847076462 0.85799773401993 0.991548042105264 GO:0008235 metalloexopeptidase activity 1/551 66/18639 0.0151515151515152 0.512539184952978 0.862482489741382 0.994663243854705 GO:1990782 protein tyrosine kinase binding 2/551 117/18639 0.0170940170940171 0.578249336870027 0.864497167533575 0.994663243854705 GO:0016500 protein-hormone receptor activity 1/551 67/18639 0.0149253731343284 0.50488934637159 0.866562183283217 0.994663243854705 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/551 67/18639 0.0149253731343284 0.50488934637159 0.866562183283217 0.994663243854705 GO:0140713 histone chaperone activity 3/551 164/18639 0.0182926829268293 0.618797308662742 0.867012687781865 0.994663243854705 GO:0030145 manganese ion binding 1/551 68/18639 0.0147058823529412 0.497464503042596 0.870521058849174 0.995784990282412 GO:0032934 sterol binding 1/551 68/18639 0.0147058823529412 0.497464503042596 0.870521058849174 0.995784990282412 GO:0005543 phospholipid binding 11/551 497/18639 0.0221327967806841 0.748699091098314 0.872911290175344 0.997069935222054 GO:0002039 p53 binding 1/551 69/18639 0.0144927536231884 0.490254872563718 0.874362688086915 0.997280341339714 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/551 122/18639 0.0163934426229508 0.554550593555681 0.879570009486815 0.999992004914144 GO:0003823 antigen binding 3/551 174/18639 0.0172413793103448 0.583234244946492 0.891670378075125 0.999992004914144 GO:0019003 GDP binding 1/551 75/18639 0.0133333333333333 0.451034482758621 0.895137406226032 0.999992004914144 GO:0017022 myosin binding 1/551 76/18639 0.0131578947368421 0.445099818511797 0.89824984369476 0.999992004914144 GO:0051536 iron-sulfur cluster binding 1/551 76/18639 0.0131578947368421 0.445099818511797 0.89824984369476 0.999992004914144 GO:0016757 glycosyltransferase activity 5/551 267/18639 0.0187265917602996 0.633475397132894 0.899233416218599 0.999992004914144 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/551 130/18639 0.0153846153846154 0.520424403183024 0.900499504765952 0.999992004914144 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/551 130/18639 0.0153846153846154 0.520424403183024 0.900499504765952 0.999992004914144 GO:0003724 RNA helicase activity 1/551 77/18639 0.012987012987013 0.439319301388267 0.901270063278027 0.999992004914144 GO:0019199 transmembrane receptor protein kinase activity 1/551 78/18639 0.0128205128205128 0.43368700265252 0.904200792463126 0.999992004914144 GO:0045182 translation regulator activity 7/551 356/18639 0.0196629213483146 0.665149166989539 0.90516990202578 0.999992004914144 GO:0008186 ATP-dependent activity, acting on RNA 1/551 79/18639 0.0126582278481013 0.428197293758184 0.907044678210274 0.999992004914144 GO:0015370 solute:sodium symporter activity 1/551 79/18639 0.0126582278481013 0.428197293758184 0.907044678210274 0.999992004914144 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 4/551 229/18639 0.0174672489082969 0.590874868242734 0.910084391723639 0.999992004914144 GO:0015297 antiporter activity 2/551 135/18639 0.0148148148148148 0.501149425287356 0.911804889569367 0.999992004914144 GO:0030971 receptor tyrosine kinase binding 1/551 81/18639 0.0123456790123457 0.417624521072797 0.912482118766147 0.999992004914144 GO:0016779 nucleotidyltransferase activity 2/551 136/18639 0.0147058823529412 0.497464503042596 0.913916636046978 0.999992004914144 GO:0005125 cytokine activity 4/551 234/18639 0.0170940170940171 0.578249336870027 0.918325108382285 0.999992004914144 GO:0140597 protein carrier chaperone 3/551 188/18639 0.0159574468085106 0.53980190755686 0.919312962982057 0.999992004914144 GO:0140767 enzyme-substrate adaptor activity 2/551 139/18639 0.0143884892086331 0.486727859092037 0.919970807394716 0.999992004914144 GO:0004527 exonuclease activity 1/551 84/18639 0.0119047619047619 0.402709359605911 0.920048755332254 0.999992004914144 GO:0019902 phosphatase binding 3/551 190/18639 0.0157894736842105 0.534119782214156 0.922689577767118 0.999992004914144 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/551 86/18639 0.0116279069767442 0.393344025661588 0.924726761020683 0.999992004914144 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/551 91/18639 0.010989010989011 0.371731716559303 0.93526092319251 0.999992004914144 GO:0043178 alcohol binding 1/551 92/18639 0.0108695652173913 0.367691154422789 0.937184107973669 0.999992004914144 GO:0051213 dioxygenase activity 1/551 93/18639 0.010752688172043 0.363737486095662 0.939050261880312 0.999992004914144 GO:0000510 H3-H4 histone complex chaperone activity 2/551 151/18639 0.0132450331125828 0.448047499429093 0.940403427039945 0.999992004914144 GO:0140584 chromatin extrusion motor activity 2/551 151/18639 0.0132450331125828 0.448047499429093 0.940403427039945 0.999992004914144 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/551 151/18639 0.0132450331125828 0.448047499429093 0.940403427039945 0.999992004914144 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/551 151/18639 0.0132450331125828 0.448047499429093 0.940403427039945 0.999992004914144 GO:0016410 N-acyltransferase activity 1/551 94/18639 0.0106382978723404 0.35986793837124 0.940861073144409 0.999992004914144 GO:0015616 DNA translocase activity 2/551 152/18639 0.0131578947368421 0.445099818511797 0.941861918648289 0.999992004914144 GO:0140674 ATP-dependent histone chaperone activity 2/551 152/18639 0.0131578947368421 0.445099818511797 0.941861918648289 0.999992004914144 GO:0061775 cohesin loader activity 2/551 153/18639 0.0130718954248366 0.442190669371197 0.943286470146446 0.999992004914144 GO:0016407 acetyltransferase activity 1/551 96/18639 0.0104166666666667 0.352370689655172 0.944323172710266 0.999992004914144 GO:0004674 protein serine/threonine kinase activity 8/551 433/18639 0.0184757505773672 0.624990045393008 0.944760737317649 0.999992004914144 GO:0005516 calmodulin binding 3/551 207/18639 0.0144927536231884 0.490254872563718 0.946572188619203 0.999992004914144 GO:0030527 structural constituent of chromatin 1/551 98/18639 0.0102040816326531 0.345179451090781 0.947582940976096 0.999992004914144 GO:0140658 ATP-dependent chromatin remodeler activity 2/551 158/18639 0.0126582278481013 0.428197293758184 0.94992512056739 0.999992004914144 GO:0003689 DNA clamp loader activity 2/551 160/18639 0.0125 0.422844827586207 0.952367449663728 0.999992004914144 GO:0015171 amino acid transmembrane transporter activity 1/551 102/18639 0.00980392156862745 0.331643002028398 0.953542013554387 0.999992004914144 GO:0008013 beta-catenin binding 1/551 106/18639 0.00943396226415094 0.319128171763175 0.958824713227347 0.999992004914144 GO:0005096 GTPase activator activity 4/551 271/18639 0.014760147601476 0.499300165415447 0.961043181913309 0.999992004914144 GO:0004843 cysteine-type deubiquitinase activity 1/551 108/18639 0.00925925925925926 0.313218390804598 0.961236726122885 0.999992004914144 GO:1902936 phosphatidylinositol bisphosphate binding 1/551 111/18639 0.00900900900900901 0.30475302889096 0.96459286483479 0.999992004914144 GO:0005085 guanyl-nucleotide exchange factor activity 3/551 230/18639 0.0130434782608696 0.441229385307346 0.968096868633251 0.999992004914144 GO:1901981 phosphatidylinositol phosphate binding 2/551 185/18639 0.0108108108108108 0.365703634669152 0.974732910618705 0.999992004914144 GO:0004519 endonuclease activity 1/551 127/18639 0.0078740157480315 0.266358946510996 0.978161472633696 0.999992004914144 GO:0035591 signaling adaptor activity 1/551 129/18639 0.00775193798449612 0.262229350441059 0.979442184121017 0.999992004914144 GO:0016758 hexosyltransferase activity 2/551 197/18639 0.0101522842639594 0.343427271136006 0.981460202216781 0.999992004914144 GO:0035173 histone kinase activity 5/551 360/18639 0.0138888888888889 0.469827586206897 0.98282372477559 0.999992004914144 GO:0106310 protein serine kinase activity 5/551 361/18639 0.0138504155124654 0.46852612474926 0.983171053191499 0.999992004914144 GO:0004518 nuclease activity 2/551 209/18639 0.00956937799043062 0.32370895891767 0.98643669348618 0.999992004914144 GO:0019903 protein phosphatase binding 1/551 144/18639 0.00694444444444444 0.234913793103448 0.986937168576983 0.999992004914144 GO:0019955 cytokine binding 1/551 144/18639 0.00694444444444444 0.234913793103448 0.986937168576983 0.999992004914144 GO:0016741 transferase activity, transferring one-carbon groups 2/551 215/18639 0.00930232558139535 0.31467522052927 0.988410921378045 0.999992004914144 GO:0030695 GTPase regulator activity 7/551 489/18639 0.0143149284253579 0.484239475354347 0.990769796682047 0.999992004914144 GO:0060589 nucleoside-triphosphatase regulator activity 7/551 490/18639 0.0142857142857143 0.483251231527094 0.990945739609775 0.999992004914144 GO:0035091 phosphatidylinositol binding 3/551 284/18639 0.0105633802816901 0.357333657115104 0.99102281929957 0.999992004914144 GO:0015081 sodium ion transmembrane transporter activity 1/551 164/18639 0.00609756097560976 0.206265769554247 0.992868207081193 0.999992004914144 GO:0016874 ligase activity 1/551 167/18639 0.00598802395209581 0.202560396448482 0.993487495733966 0.999992004914144 GO:0141003 histone H2AX kinase activity 4/551 354/18639 0.0112994350282486 0.382232612507306 0.993612330368545 0.999992004914144 GO:0140996 histone H3 kinase activity 4/551 357/18639 0.0112044817927171 0.37902057374674 0.994034786896352 0.999992004914144 GO:0140030 modification-dependent protein binding 1/551 173/18639 0.00578034682080925 0.195535180386685 0.994569659087446 0.999992004914144 GO:0004842 ubiquitin-protein transferase activity 5/551 449/18639 0.0111358574610245 0.376699178250518 0.997450604905009 0.999992004914144 GO:0008168 methyltransferase activity 1/551 204/18639 0.00490196078431373 0.165821501014199 0.997878447505634 0.999992004914144 GO:0061630 ubiquitin protein ligase activity 3/551 353/18639 0.0084985835694051 0.287486568330566 0.998373555006376 0.999992004914144 GO:0019787 ubiquitin-like protein transferase activity 5/551 479/18639 0.0104384133611691 0.353106327838169 0.998706007860053 0.999992004914144 GO:0061659 ubiquitin-like protein ligase activity 3/551 372/18639 0.00806451612903226 0.272803114571746 0.998997502641219 0.999992004914144 GO:0016755 aminoacyltransferase activity 5/551 496/18639 0.0100806451612903 0.341003893214683 0.999124697904596 0.999992004914144 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/551 243/18639 0.00411522633744856 0.139208173690932 0.999351134863903 0.999992004914144 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:0004711 ribosomal protein S6 kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:0035175 histone H3S10 kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:0035979 histone H2AXS139 kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:0044022 histone H3S28 kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:0044023 histone H4S1 kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:0044024 histone H2AS1 kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:0044025 histone H2BS14 kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:0072354 histone H3T3 kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:0072371 histone H2AS121 kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:0140823 histone H2BS36 kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:0140855 histone H3S57 kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:0140995 histone H2A kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:0140997 histone H4 kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:0140998 histone H2B kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:1990244 histone H2AT120 kinase activity 1/551 245/18639 0.00408163265306122 0.138071780436312 0.999389423600358 0.999992004914144 GO:0004677 DNA-dependent protein kinase activity 1/551 246/18639 0.0040650406504065 0.137510513036165 0.999407713673002 0.999992004914144 GO:0140857 histone H3T45 kinase activity 1/551 246/18639 0.0040650406504065 0.137510513036165 0.999407713673002 0.999992004914144 GO:0035402 histone H3T11 kinase activity 1/551 247/18639 0.00404858299595142 0.136953790311322 0.999425456823449 0.999992004914144 GO:0035403 histone H3T6 kinase activity 1/551 247/18639 0.00404858299595142 0.136953790311322 0.999425456823449 0.999992004914144 GO:0004679 AMP-activated protein kinase activity 1/551 248/18639 0.00403225806451613 0.136401557285873 0.999442669377292 0.999992004914144 GO:0005216 monoatomic ion channel activity 3/551 448/18639 0.00669642857142857 0.226524014778325 0.999861798605056 0.999992004914144 GO:0030371 translation repressor activity 1/551 329/18639 0.00303951367781155 0.102819410963211 0.999952827081559 0.999992004914144 GO:0046873 metal ion transmembrane transporter activity 2/551 450/18639 0.00444444444444444 0.150344827586207 0.999982605502008 0.999992004914144 GO:0140098 catalytic activity, acting on RNA 1/551 387/18639 0.00258397932816537 0.0874097834803528 0.999992004914144 0.999992004914144