ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 81/816 175/18639 0.462857142857143 10.5725420168067 7.12349311822878e-63 6.84567688661786e-60 GO:0045296 cadherin binding 56/816 334/18639 0.167664670658683 3.8297816132441 3.05113273430742e-18 1.46606927883472e-15 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 23/816 68/18639 0.338235294117647 7.72594074394464 5.11944609406043e-15 1.63992923213069e-12 GO:0004601 peroxidase activity 21/816 57/18639 0.368421052631579 8.41544117647059 1.09023645759463e-14 2.26207652006964e-12 GO:0009055 electron transfer activity 29/816 116/18639 0.25 5.71047794117647 1.17693887620689e-14 2.26207652006964e-12 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 21/816 59/18639 0.355932203389831 8.13017198404786 2.44189908433315e-14 3.91110836674027e-12 GO:0016209 antioxidant activity 22/816 86/18639 0.255813953488372 5.84327975376197 1.15612329569711e-11 1.58719212452132e-09 GO:0019843 rRNA binding 19/816 65/18639 0.292307692307692 6.6768665158371 2.284927640483e-11 2.74476932813021e-09 GO:0051082 unfolded protein binding 25/816 121/18639 0.206611570247934 4.71940325717064 7.25697739363398e-11 7.69605890605935e-09 GO:0008137 NADH dehydrogenase (ubiquinone) activity 15/816 41/18639 0.365853658536585 8.35679698708752 8.00838595843845e-11 7.69605890605935e-09 GO:0022853 active monoatomic ion transmembrane transporter activity 24/816 118/18639 0.203389830508475 4.64581256231306 2.45268435028688e-10 2.05541803473707e-08 GO:0003954 NADH dehydrogenase activity 15/816 44/18639 0.340909090909091 7.78701537433155 2.56659900279343e-10 2.05541803473707e-08 GO:0031720 haptoglobin binding 8/816 10/18639 0.8 18.2735294117647 5.43148669785247e-10 4.01512208972017e-08 GO:0015399 primary active transmembrane transporter activity 28/816 166/18639 0.168674698795181 3.85285258681786 7.77497519904288e-10 5.33696511877157e-08 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 16/816 58/18639 0.275862068965517 6.30121703853955 2.2414741671444e-09 1.43603778308385e-07 GO:0015078 proton transmembrane transporter activity 28/816 185/18639 0.151351351351351 3.45715421303657 9.51313301360587e-09 5.71382551629702e-07 GO:0048027 mRNA 5'-UTR binding 10/816 24/18639 0.416666666666667 9.51746323529412 2.74614609802769e-08 1.55238023541448e-06 GO:0005344 oxygen carrier activity 8/816 14/18639 0.571428571428571 13.0525210084034 3.09799168715421e-08 1.65398333964178e-06 GO:0140662 ATP-dependent protein folding chaperone 12/816 40/18639 0.3 6.85257352941176 8.23440423305463e-08 4.16487498313974e-06 GO:0044183 protein folding chaperone 16/816 75/18639 0.213333333333333 4.87294117647059 1.19312982494115e-07 5.73298880884221e-06 GO:0016860 intramolecular oxidoreductase activity 13/816 53/18639 0.245283018867925 5.60273307436182 3.26852654256529e-07 1.49574000352631e-05 GO:0015036 disulfide oxidoreductase activity 11/816 40/18639 0.275 6.28152573529412 7.63068670439663e-07 3.33322269223871e-05 GO:0016651 oxidoreductase activity, acting on NAD(P)H 16/816 88/18639 0.181818181818182 4.15307486631016 1.18642866714551e-06 4.73611322440074e-05 GO:0015035 protein-disulfide reductase activity 10/816 34/18639 0.294117647058824 6.71820934256055 1.23207940280977e-06 4.73611322440074e-05 GO:0019825 oxygen binding 10/816 34/18639 0.294117647058824 6.71820934256055 1.23207940280977e-06 4.73611322440074e-05 GO:0004857 enzyme inhibitor activity 40/816 416/18639 0.0961538461538462 2.19633766968326 2.8053841752887e-06 0.000103691315094325 GO:0022804 active transmembrane transporter activity 42/816 457/18639 0.0919037199124726 2.09925666108894 5.00082587130945e-06 0.000177992357864014 GO:0003743 translation initiation factor activity 11/816 51/18639 0.215686274509804 4.92668685121107 1.01195271422961e-05 0.00034731662799095 GO:0016853 isomerase activity 22/816 180/18639 0.122222222222222 2.79178921568627 1.33740018938615e-05 0.000433246297732175 GO:0008135 translation factor activity, RNA binding 14/816 83/18639 0.168674698795181 3.85285258681786 1.35248584099534e-05 0.000433246297732175 GO:0044389 ubiquitin-like protein ligase binding 32/816 322/18639 0.0993788819875776 2.27000365363537 1.41235238358831e-05 0.000437829238912376 GO:0180051 translation factor activity 14/816 84/18639 0.166666666666667 3.80698529411765 1.55853013431196e-05 0.000468046080960561 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 11/816 54/18639 0.203703703703704 4.65298202614379 1.80415756818371e-05 0.000525392552431679 GO:0031386 protein tag activity 6/816 15/18639 0.4 9.13676470588235 2.46264850937198e-05 0.000657390338196243 GO:0055105 ubiquitin-protein transferase inhibitor activity 6/816 15/18639 0.4 9.13676470588235 2.46264850937198e-05 0.000657390338196243 GO:0141047 molecular tag activity 6/816 15/18639 0.4 9.13676470588235 2.46264850937198e-05 0.000657390338196243 GO:0031625 ubiquitin protein ligase binding 30/816 302/18639 0.0993377483443709 2.26906408258668 2.6183493911171e-05 0.000680063179692847 GO:0140517 protein-RNA adaptor activity 7/816 22/18639 0.318181818181818 7.26788101604278 2.87572767256176e-05 0.000721405792936389 GO:0005200 structural constituent of cytoskeleton 16/816 112/18639 0.142857142857143 3.26313025210084 2.92766138652645e-05 0.000721405792936389 GO:0004602 glutathione peroxidase activity 7/816 23/18639 0.304347826086957 6.95188618925831 3.9782426517017e-05 0.000955772797071333 GO:1990948 ubiquitin ligase inhibitor activity 5/816 11/18639 0.454545454545455 10.3826871657754 5.88669124177103e-05 0.00137978299593706 GO:0043021 ribonucleoprotein complex binding 20/816 177/18639 0.112994350282486 2.58100697906281 9.95337693755273e-05 0.00227742743737814 GO:0008301 DNA binding, bending 6/816 19/18639 0.315789473684211 7.21323529411765 0.000114834139839351 0.00256640949733992 GO:0055106 ubiquitin-protein transferase regulator activity 8/816 36/18639 0.222222222222222 5.07598039215686 0.000132387708372612 0.00289146790332001 GO:0003697 single-stranded DNA binding 15/816 121/18639 0.12396694214876 2.83164195430238 0.000261657725867243 0.00558784610129823 GO:0004129 cytochrome-c oxidase activity 5/816 15/18639 0.333333333333333 7.61397058823529 0.000330465917562674 0.00675697333569638 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 5/816 15/18639 0.333333333333333 7.61397058823529 0.000330465917562674 0.00675697333569638 GO:0051015 actin filament binding 21/816 209/18639 0.100478468899522 2.29512032085561 0.000350405905368852 0.00701541823040557 GO:0043022 ribosome binding 14/816 112/18639 0.125 2.85523897058824 0.000380832858877248 0.00746898729349051 GO:0016675 oxidoreductase activity, acting on a heme group of donors 5/816 16/18639 0.3125 7.13809742647059 0.00046343017215522 0.00873247834198365 GO:0017070 U6 snRNA binding 5/816 16/18639 0.3125 7.13809742647059 0.00046343017215522 0.00873247834198365 GO:0003756 protein disulfide isomerase activity 5/816 19/18639 0.263157894736842 6.01102941176471 0.00110587878397645 0.0200518775736108 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 5/816 19/18639 0.263157894736842 6.01102941176471 0.00110587878397645 0.0200518775736108 GO:0043560 insulin receptor substrate binding 4/816 13/18639 0.307692307692308 7.02828054298643 0.0018987808257563 0.0337912661768853 GO:0051087 protein-folding chaperone binding 14/816 134/18639 0.104477611940299 2.38646839332748 0.00224086952767495 0.0390255190946174 GO:0017069 snRNA binding 8/816 54/18639 0.148148148148148 3.38398692810457 0.00227411973912443 0.0390255190946174 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 13/816 122/18639 0.10655737704918 2.43397420443587 0.00266465987219388 0.0449252304768126 GO:0001618 virus receptor activity 10/816 81/18639 0.123456790123457 2.81998910675381 0.00276293270044394 0.0457789366401143 GO:0019212 phosphatase inhibitor activity 8/816 56/18639 0.142857142857143 3.26313025210084 0.00287572664797436 0.0468402255712434 GO:0140272 exogenous protein binding 10/816 82/18639 0.121951219512195 2.78559899569584 0.00302620413623276 0.048469702915328 GO:0140104 molecular carrier activity 21/816 249/18639 0.0843373493975904 1.92642629340893 0.0032090226814644 0.0505552589653654 GO:0020037 heme binding 14/816 142/18639 0.0985915492957746 2.25201946975973 0.00381947585790356 0.0592018757975052 GO:0005159 insulin-like growth factor receptor binding 4/816 16/18639 0.25 5.71047794117647 0.00435236170385051 0.0663907872603229 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 7/816 48/18639 0.145833333333333 3.33111213235294 0.00461876174510514 0.0693535943288444 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 13/816 132/18639 0.0984848484848485 2.24958221925134 0.00525401963405205 0.0776786595126772 GO:0098631 cell adhesion mediator activity 9/816 76/18639 0.118421052631579 2.70496323529412 0.00583613614584614 0.0849776793357294 GO:0097718 disordered domain specific binding 5/816 28/18639 0.178571428571429 4.07891281512605 0.00674827138047333 0.0964651879660534 GO:0098641 cadherin binding involved in cell-cell adhesion 4/816 18/18639 0.222222222222222 5.07598039215686 0.00682584056367495 0.0964651879660534 GO:0046906 tetrapyrrole binding 14/816 152/18639 0.0921052631578947 2.10386029411765 0.00695568228171338 0.0968755169960371 GO:0061135 endopeptidase regulator activity 16/816 184/18639 0.0869565217391304 1.98625319693095 0.00706212844564568 0.0969529348037929 GO:0001094 TFIID-class transcription factor complex binding 3/816 10/18639 0.3 6.85257352941176 0.00796187897114725 0.105487860229505 GO:0005528 FK506 binding 3/816 10/18639 0.3 6.85257352941176 0.00796187897114725 0.105487860229505 GO:0004864 protein phosphatase inhibitor activity 7/816 53/18639 0.132075471698113 3.01685627081021 0.0080131256990155 0.105487860229505 GO:0048306 calcium-dependent protein binding 9/816 80/18639 0.1125 2.56971507352941 0.00814450098392906 0.105768451966971 GO:0061650 ubiquitin-like protein conjugating enzyme activity 6/816 41/18639 0.146341463414634 3.34271879483501 0.00839265752609734 0.107537918434394 GO:0042056 chemoattractant activity 6/816 42/18639 0.142857142857143 3.26313025210084 0.00943768244414625 0.119337010905586 GO:0098632 cell-cell adhesion mediator activity 7/816 55/18639 0.127272727272727 2.90715240641711 0.00978760233443225 0.12215436160246 GO:0005536 D-glucose binding 3/816 11/18639 0.272727272727273 6.22961229946524 0.010595066775921 0.124169014288538 GO:0010854 adenylate cyclase regulator activity 3/816 11/18639 0.272727272727273 6.22961229946524 0.010595066775921 0.124169014288538 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 3/816 11/18639 0.272727272727273 6.22961229946524 0.010595066775921 0.124169014288538 GO:0050786 RAGE receptor binding 3/816 11/18639 0.272727272727273 6.22961229946524 0.010595066775921 0.124169014288538 GO:0070990 snRNP binding 3/816 11/18639 0.272727272727273 6.22961229946524 0.010595066775921 0.124169014288538 GO:0019205 nucleobase-containing compound kinase activity 6/816 44/18639 0.136363636363636 3.11480614973262 0.011800200960577 0.136626423170054 GO:0031369 translation initiation factor binding 5/816 32/18639 0.15625 3.56904871323529 0.0119776083022993 0.137029542601305 GO:0005527 macrolide binding 3/816 12/18639 0.25 5.71047794117647 0.0136729462414955 0.149314787932695 GO:0010853 cyclase activator activity 3/816 12/18639 0.25 5.71047794117647 0.0136729462414955 0.149314787932695 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 3/816 12/18639 0.25 5.71047794117647 0.0136729462414955 0.149314787932695 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/816 12/18639 0.25 5.71047794117647 0.0136729462414955 0.149314787932695 GO:0070034 telomerase RNA binding 4/816 22/18639 0.181818181818182 4.15307486631016 0.0142074864645106 0.153408926880839 GO:0016829 lyase activity 16/816 200/18639 0.08 1.82735294117647 0.0149481530130946 0.159613056062043 GO:0005504 fatty acid binding 6/816 47/18639 0.127659574468085 2.9159887359199 0.0160808348630771 0.169820684652935 GO:0030414 peptidase inhibitor activity 14/816 169/18639 0.0828402366863905 1.89222937695788 0.0166740622746638 0.172231179452445 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 7/816 61/18639 0.114754098360656 2.62120298939248 0.0168191031890279 0.172231179452445 GO:0005172 vascular endothelial growth factor receptor binding 3/816 13/18639 0.230769230769231 5.27121040723982 0.0172051958662172 0.172231179452445 GO:0019855 calcium channel inhibitor activity 3/816 13/18639 0.230769230769231 5.27121040723982 0.0172051958662172 0.172231179452445 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 3/816 13/18639 0.230769230769231 5.27121040723982 0.0172051958662172 0.172231179452445 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 5/816 36/18639 0.138888888888889 3.17248774509804 0.0194383275396533 0.188689219854614 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 5/816 36/18639 0.138888888888889 3.17248774509804 0.0194383275396533 0.188689219854614 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 5/816 36/18639 0.138888888888889 3.17248774509804 0.0194383275396533 0.188689219854614 GO:0003779 actin binding 29/816 443/18639 0.0654627539503386 1.49529444960829 0.0206479739796852 0.198427029944775 GO:0032036 myosin heavy chain binding 3/816 14/18639 0.214285714285714 4.89469537815126 0.0211974623624502 0.199713346375634 GO:0044548 S100 protein binding 3/816 14/18639 0.214285714285714 4.89469537815126 0.0211974623624502 0.199713346375634 GO:0061134 peptidase regulator activity 17/816 226/18639 0.0752212389380531 1.71819690265487 0.0214110906692709 0.199767554690964 GO:0016835 carbon-oxygen lyase activity 8/816 79/18639 0.10126582278481 2.31310498883098 0.0220505766639848 0.201815277848471 GO:0033293 monocarboxylic acid binding 8/816 79/18639 0.10126582278481 2.31310498883098 0.0220505766639848 0.201815277848471 GO:0004867 serine-type endopeptidase inhibitor activity 9/816 95/18639 0.0947368421052632 2.16397058823529 0.0232505045826917 0.210789951924214 GO:0004866 endopeptidase inhibitor activity 13/816 161/18639 0.0807453416149068 1.84437796857874 0.0248000364860713 0.21767987984484 GO:0005178 integrin binding 13/816 161/18639 0.0807453416149068 1.84437796857874 0.0248000364860713 0.21767987984484 GO:0000287 magnesium ion binding 17/816 230/18639 0.0739130434782609 1.6883152173913 0.0248710211814013 0.21767987984484 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 11/816 128/18639 0.0859375 1.96297679227941 0.0249165315118964 0.21767987984484 GO:0005080 protein kinase C binding 6/816 52/18639 0.115384615384615 2.63560520361991 0.0254055355148494 0.219952429097029 GO:0033130 acetylcholine receptor binding 3/816 15/18639 0.2 4.56838235294118 0.0256517957478311 0.220101568872015 GO:0000217 DNA secondary structure binding 5/816 39/18639 0.128205128205128 2.92845022624434 0.0266846420448386 0.224946850921841 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 5/816 39/18639 0.128205128205128 2.92845022624434 0.0266846420448386 0.224946850921841 GO:0016887 ATP hydrolysis activity 27/816 417/18639 0.0647482014388489 1.47897270418959 0.0280744681015816 0.234604903005391 GO:0008266 poly(U) RNA binding 4/816 27/18639 0.148148148148148 3.38398692810457 0.0287081409189397 0.234734781482405 GO:0008320 protein transmembrane transporter activity 4/816 27/18639 0.148148148148148 3.38398692810457 0.0287081409189397 0.234734781482405 GO:0030145 manganese ion binding 7/816 68/18639 0.102941176470588 2.35137326989619 0.0288227931476835 0.234734781482405 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 5/816 40/18639 0.125 2.85523897058824 0.0294348350044122 0.235723970327001 GO:0030331 nuclear estrogen receptor binding 5/816 40/18639 0.125 2.85523897058824 0.0294348350044122 0.235723970327001 GO:0003925 G protein activity 6/816 54/18639 0.111111111111111 2.53799019607843 0.0299705896363387 0.236079808528864 GO:0051287 NAD binding 6/816 54/18639 0.111111111111111 2.53799019607843 0.0299705896363387 0.236079808528864 GO:0019887 protein kinase regulator activity 18/816 255/18639 0.0705882352941176 1.61237024221453 0.0319525829970223 0.249645790732833 GO:0051537 2 iron, 2 sulfur cluster binding 4/816 28/18639 0.142857142857143 3.26313025210084 0.0323681191753508 0.250708940799908 GO:0019208 phosphatase regulator activity 10/816 117/18639 0.0854700854700855 1.95230015082956 0.0326104241415073 0.250708940799908 GO:0003713 transcription coactivator activity 18/816 256/18639 0.0703125 1.60607192095588 0.0330258280974442 0.251887466679713 GO:0008307 structural constituent of muscle 5/816 42/18639 0.119047619047619 2.71927521008403 0.0354546133312095 0.259681347501377 GO:0016859 cis-trans isomerase activity 5/816 42/18639 0.119047619047619 2.71927521008403 0.0354546133312095 0.259681347501377 GO:0004029 aldehyde dehydrogenase (NAD+) activity 3/816 17/18639 0.176470588235294 4.03092560553633 0.0359392499663716 0.259681347501377 GO:0004550 nucleoside diphosphate kinase activity 3/816 17/18639 0.176470588235294 4.03092560553633 0.0359392499663716 0.259681347501377 GO:0046965 nuclear retinoid X receptor binding 3/816 17/18639 0.176470588235294 4.03092560553633 0.0359392499663716 0.259681347501377 GO:0051787 misfolded protein binding 3/816 17/18639 0.176470588235294 4.03092560553633 0.0359392499663716 0.259681347501377 GO:1990226 histone methyltransferase binding 3/816 17/18639 0.176470588235294 4.03092560553633 0.0359392499663716 0.259681347501377 GO:0003785 actin monomer binding 4/816 29/18639 0.137931034482759 3.15060851926978 0.0362884473331157 0.2602477454263 GO:0044325 transmembrane transporter binding 11/816 136/18639 0.0808823529411765 1.84750756920415 0.0366098473473648 0.260607876302352 GO:0005506 iron ion binding 12/816 154/18639 0.0779220779220779 1.77988922841864 0.0382538764723806 0.26867727352647 GO:0016922 nuclear receptor binding 11/816 137/18639 0.0802919708029197 1.83402211249463 0.0383025873809848 0.26867727352647 GO:0140297 DNA-binding transcription factor binding 30/816 488/18639 0.0614754098360656 1.40421588717454 0.0390905170584399 0.272217296327251 GO:0043539 protein serine/threonine kinase activator activity 7/816 73/18639 0.0958904109589041 2.19032030620467 0.0402803093106959 0.275829699743828 GO:0001968 fibronectin binding 4/816 30/18639 0.133333333333333 3.04558823529412 0.040470330555546 0.275829699743828 GO:0008187 poly-pyrimidine tract binding 4/816 30/18639 0.133333333333333 3.04558823529412 0.040470330555546 0.275829699743828 GO:0000400 four-way junction DNA binding 3/816 18/18639 0.166666666666667 3.80698529411765 0.0417619318469109 0.280651863670499 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 3/816 18/18639 0.166666666666667 3.80698529411765 0.0417619318469109 0.280651863670499 GO:0030547 signaling receptor inhibitor activity 5/816 44/18639 0.113636363636364 2.59567179144385 0.0421809670263723 0.28149937022461 GO:0031491 nucleosome binding 7/816 74/18639 0.0945945945945946 2.16072138314785 0.0428815300605755 0.282254454713788 GO:0048029 monosaccharide binding 7/816 74/18639 0.0945945945945946 2.16072138314785 0.0428815300605755 0.282254454713788 GO:0033218 amide binding 17/816 247/18639 0.0688259109311741 1.57211538461538 0.0444024229508476 0.290277064324929 GO:0019888 protein phosphatase regulator activity 9/816 107/18639 0.0841121495327103 1.92128229796592 0.0450255963083483 0.29236214900218 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 3/816 19/18639 0.157894736842105 3.60661764705882 0.0480264508735328 0.309754491875604 GO:0019207 kinase regulator activity 19/816 287/18639 0.0662020905923345 1.51218231194917 0.0486258284007792 0.311529473954325 GO:0022884 macromolecule transmembrane transporter activity 4/816 32/18639 0.125 2.85523897058824 0.0496193322525091 0.311699241598506 GO:0140142 nucleocytoplasmic carrier activity 4/816 32/18639 0.125 2.85523897058824 0.0496193322525091 0.311699241598506 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 5/816 46/18639 0.108695652173913 2.48281649616368 0.0496253735323324 0.311699241598506 GO:0051540 metal cluster binding 7/816 77/18639 0.0909090909090909 2.07653743315508 0.0513261209675659 0.320288326297603 GO:0015631 tubulin binding 24/816 385/18639 0.0623376623376623 1.42391138273491 0.0527717368887168 0.327184768710044 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 3/816 20/18639 0.15 3.42628676470588 0.0547222666182539 0.332836064684443 GO:0010851 cyclase regulator activity 3/816 20/18639 0.15 3.42628676470588 0.0547222666182539 0.332836064684443 GO:0043024 ribosomal small subunit binding 3/816 20/18639 0.15 3.42628676470588 0.0547222666182539 0.332836064684443 GO:1901682 sulfur compound transmembrane transporter activity 6/816 63/18639 0.0952380952380952 2.17542016806723 0.0569715603859041 0.344337544219207 GO:0090482 vitamin transmembrane transporter activity 4/816 34/18639 0.117647058823529 2.68728373702422 0.0598082772073504 0.359223464976648 GO:0008017 microtubule binding 18/816 276/18639 0.0652173913043478 1.48968989769821 0.0604592854072242 0.360878094884115 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 3/816 21/18639 0.142857142857143 3.26313025210084 0.0618372026841905 0.366824393700661 GO:0038024 cargo receptor activity 6/816 65/18639 0.0923076923076923 2.10848416289593 0.0644645267281572 0.376569121520063 GO:0061631 ubiquitin conjugating enzyme activity 4/816 35/18639 0.114285714285714 2.61050420168067 0.065287300111563 0.376569121520063 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/816 10/18639 0.2 4.56838235294118 0.068224355156811 0.376569121520063 GO:0005345 purine nucleobase transmembrane transporter activity 2/816 10/18639 0.2 4.56838235294118 0.068224355156811 0.376569121520063 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/816 10/18639 0.2 4.56838235294118 0.068224355156811 0.376569121520063 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/816 10/18639 0.2 4.56838235294118 0.068224355156811 0.376569121520063 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 2/816 10/18639 0.2 4.56838235294118 0.068224355156811 0.376569121520063 GO:0030957 Tat protein binding 2/816 10/18639 0.2 4.56838235294118 0.068224355156811 0.376569121520063 GO:0031996 thioesterase binding 2/816 10/18639 0.2 4.56838235294118 0.068224355156811 0.376569121520063 GO:0035374 chondroitin sulfate binding 2/816 10/18639 0.2 4.56838235294118 0.068224355156811 0.376569121520063 GO:0047429 nucleoside triphosphate diphosphatase activity 2/816 10/18639 0.2 4.56838235294118 0.068224355156811 0.376569121520063 GO:0050815 phosphoserine residue binding 2/816 10/18639 0.2 4.56838235294118 0.068224355156811 0.376569121520063 GO:0034062 5'-3' RNA polymerase activity 3/816 22/18639 0.136363636363636 3.11480614973262 0.0693576841925611 0.376569121520063 GO:0061133 endopeptidase activator activity 3/816 22/18639 0.136363636363636 3.11480614973262 0.0693576841925611 0.376569121520063 GO:0097747 RNA polymerase activity 3/816 22/18639 0.136363636363636 3.11480614973262 0.0693576841925611 0.376569121520063 GO:0004869 cysteine-type endopeptidase inhibitor activity 4/816 36/18639 0.111111111111111 2.53799019607843 0.0710184216830517 0.383320881038959 GO:0005048 signal sequence binding 5/816 51/18639 0.0980392156862745 2.23940311418685 0.0713989986534585 0.383320881038959 GO:0004860 protein kinase inhibitor activity 7/816 84/18639 0.0833333333333333 1.90349264705882 0.0748592674028695 0.397457215326837 GO:0051117 ATPase binding 7/816 84/18639 0.0833333333333333 1.90349264705882 0.0748592674028695 0.397457215326837 GO:0042393 histone binding 16/816 247/18639 0.0647773279352227 1.47963800904977 0.0769739918929923 0.399336717959732 GO:0043394 proteoglycan binding 4/816 37/18639 0.108108108108108 2.46939586645469 0.0769976557583976 0.399336717959732 GO:0017134 fibroblast growth factor binding 3/816 23/18639 0.130434782608696 2.97937979539642 0.0772689544322629 0.399336717959732 GO:0043274 phospholipase binding 3/816 23/18639 0.130434782608696 2.97937979539642 0.0772689544322629 0.399336717959732 GO:0000099 sulfur amino acid transmembrane transporter activity 2/816 11/18639 0.181818181818182 4.15307486631016 0.0810308636858977 0.399336717959732 GO:0015173 aromatic amino acid transmembrane transporter activity 2/816 11/18639 0.181818181818182 4.15307486631016 0.0810308636858977 0.399336717959732 GO:0015205 nucleobase transmembrane transporter activity 2/816 11/18639 0.181818181818182 4.15307486631016 0.0810308636858977 0.399336717959732 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/816 11/18639 0.181818181818182 4.15307486631016 0.0810308636858977 0.399336717959732 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/816 11/18639 0.181818181818182 4.15307486631016 0.0810308636858977 0.399336717959732 GO:0019206 nucleoside kinase activity 2/816 11/18639 0.181818181818182 4.15307486631016 0.0810308636858977 0.399336717959732 GO:0032050 clathrin heavy chain binding 2/816 11/18639 0.181818181818182 4.15307486631016 0.0810308636858977 0.399336717959732 GO:0034056 estrogen response element binding 2/816 11/18639 0.181818181818182 4.15307486631016 0.0810308636858977 0.399336717959732 GO:0034511 U3 snoRNA binding 2/816 11/18639 0.181818181818182 4.15307486631016 0.0810308636858977 0.399336717959732 GO:0045294 alpha-catenin binding 2/816 11/18639 0.181818181818182 4.15307486631016 0.0810308636858977 0.399336717959732 GO:0042162 telomeric DNA binding 4/816 38/18639 0.105263157894737 2.40441176470588 0.0832204389591525 0.40803490734564 GO:0001091 RNA polymerase II general transcription initiation factor binding 3/816 24/18639 0.125 2.85523897058824 0.0855552721768056 0.411093082809551 GO:0005540 hyaluronic acid binding 3/816 24/18639 0.125 2.85523897058824 0.0855552721768056 0.411093082809551 GO:0015295 solute:proton symporter activity 3/816 24/18639 0.125 2.85523897058824 0.0855552721768056 0.411093082809551 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 3/816 24/18639 0.125 2.85523897058824 0.0855552721768056 0.411093082809551 GO:0016776 phosphotransferase activity, phosphate group as acceptor 4/816 39/18639 0.102564102564103 2.34276018099548 0.089681672892217 0.428776555469754 GO:0140313 molecular sequestering activity 5/816 55/18639 0.0909090909090909 2.07653743315508 0.092021581453396 0.436619479495008 GO:0042974 nuclear retinoic acid receptor binding 3/816 25/18639 0.12 2.74102941176471 0.0942000910758371 0.436619479495008 GO:0004859 phospholipase inhibitor activity 2/816 12/18639 0.166666666666667 3.80698529411765 0.094502447174778 0.436619479495008 GO:0005049 nuclear export signal receptor activity 2/816 12/18639 0.166666666666667 3.80698529411765 0.094502447174778 0.436619479495008 GO:0015132 prostaglandin transmembrane transporter activity 2/816 12/18639 0.166666666666667 3.80698529411765 0.094502447174778 0.436619479495008 GO:0016208 AMP binding 2/816 12/18639 0.166666666666667 3.80698529411765 0.094502447174778 0.436619479495008 GO:0097371 MDM2/MDM4 family protein binding 2/816 12/18639 0.166666666666667 3.80698529411765 0.094502447174778 0.436619479495008 GO:0003727 single-stranded RNA binding 7/816 89/18639 0.0786516853932584 1.79655485789822 0.0949811576447932 0.436731543046154 GO:0050997 quaternary ammonium group binding 4/816 40/18639 0.1 2.28419117647059 0.0963757659908618 0.436873165647256 GO:0061791 GTPase motor activity 4/816 40/18639 0.1 2.28419117647059 0.0963757659908618 0.436873165647256 GO:1990606 membrane scission GTPase motor activity 4/816 40/18639 0.1 2.28419117647059 0.0963757659908618 0.436873165647256 GO:0019210 kinase inhibitor activity 7/816 90/18639 0.0777777777777778 1.7765931372549 0.0993329784707407 0.448164283147332 GO:0050750 low-density lipoprotein particle receptor binding 3/816 26/18639 0.115384615384615 2.63560520361991 0.103186222436854 0.457456702614932 GO:0001530 lipopolysaccharide binding 4/816 41/18639 0.0975609756097561 2.22847919655667 0.103296674784017 0.457456702614932 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/816 41/18639 0.0975609756097561 2.22847919655667 0.103296674784017 0.457456702614932 GO:0140318 protein transporter activity 4/816 41/18639 0.0975609756097561 2.22847919655667 0.103296674784017 0.457456702614932 GO:0003684 damaged DNA binding 6/816 74/18639 0.0810810810810811 1.85204689984102 0.104934151646991 0.462576696021829 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 2/816 13/18639 0.153846153846154 3.51414027149321 0.108556492867244 0.467815200203682 GO:0031432 titin binding 2/816 13/18639 0.153846153846154 3.51414027149321 0.108556492867244 0.467815200203682 GO:0070700 BMP receptor binding 2/816 13/18639 0.153846153846154 3.51414027149321 0.108556492867244 0.467815200203682 GO:0071714 icosanoid transmembrane transporter activity 2/816 13/18639 0.153846153846154 3.51414027149321 0.108556492867244 0.467815200203682 GO:0071837 HMG box domain binding 2/816 13/18639 0.153846153846154 3.51414027149321 0.108556492867244 0.467815200203682 GO:0003725 double-stranded RNA binding 6/816 75/18639 0.08 1.82735294117647 0.110094606904157 0.469605595480591 GO:0031492 nucleosomal DNA binding 4/816 42/18639 0.0952380952380952 2.17542016806723 0.110437944410628 0.469605595480591 GO:0035198 miRNA binding 4/816 42/18639 0.0952380952380952 2.17542016806723 0.110437944410628 0.469605595480591 GO:0004364 glutathione transferase activity 3/816 27/18639 0.111111111111111 2.53799019607843 0.112495982626594 0.474160698702441 GO:0023026 MHC class II protein complex binding 3/816 27/18639 0.111111111111111 2.53799019607843 0.112495982626594 0.474160698702441 GO:0045309 protein phosphorylated amino acid binding 5/816 59/18639 0.0847457627118644 1.93575523429711 0.115357248762712 0.482097840348084 GO:0051536 iron-sulfur cluster binding 6/816 76/18639 0.0789473684210526 1.80330882352941 0.115382417565098 0.482097840348084 GO:0031406 carboxylic acid binding 12/816 187/18639 0.0641711229946524 1.46579112928594 0.119881498028411 0.498727790499149 GO:0031072 heat shock protein binding 9/816 131/18639 0.0687022900763359 1.56929164795689 0.121101503719722 0.501333874426295 GO:0046875 ephrin receptor binding 3/816 28/18639 0.107142857142857 2.44734768907563 0.122111326240743 0.501333874426295 GO:0008559 ABC-type xenobiotic transporter activity 2/816 14/18639 0.142857142857143 3.26313025210084 0.123116331284709 0.501333874426295 GO:0016530 metallochaperone activity 2/816 14/18639 0.142857142857143 3.26313025210084 0.123116331284709 0.501333874426295 GO:1990825 sequence-specific mRNA binding 2/816 14/18639 0.142857142857143 3.26313025210084 0.123116331284709 0.501333874426295 GO:0043177 organic acid binding 12/816 189/18639 0.0634920634920635 1.45028011204482 0.126736261187504 0.513896822789835 GO:0001221 transcription coregulator binding 8/816 115/18639 0.0695652173913043 1.58900255754476 0.131653922795968 0.528605922650944 GO:0035250 UDP-galactosyltransferase activity 3/816 29/18639 0.103448275862069 2.36295638945233 0.1320139661147 0.528605922650944 GO:0051861 glycolipid binding 3/816 29/18639 0.103448275862069 2.36295638945233 0.1320139661147 0.528605922650944 GO:0008514 organic anion transmembrane transporter activity 16/816 269/18639 0.0594795539033457 1.35862672206429 0.133300575109058 0.531542957177615 GO:0000049 tRNA binding 6/816 80/18639 0.075 1.71314338235294 0.137765910863868 0.546191568231007 GO:0004559 alpha-mannosidase activity 2/816 15/18639 0.133333333333333 3.04558823529412 0.13811087521346 0.546191568231007 GO:0030291 protein serine/threonine kinase inhibitor activity 4/816 46/18639 0.0869565217391304 1.98625319693095 0.141065323021757 0.553199382230493 GO:0003712 transcription coregulator activity 27/816 495/18639 0.0545454545454545 1.24592245989305 0.141800761358132 0.553199382230493 GO:0031210 phosphatidylcholine binding 3/816 30/18639 0.1 2.28419117647059 0.142185481176828 0.553199382230493 GO:0033612 receptor serine/threonine kinase binding 3/816 30/18639 0.1 2.28419117647059 0.142185481176828 0.553199382230493 GO:1901681 sulfur compound binding 16/816 275/18639 0.0581818181818182 1.32898395721925 0.151927688579143 0.569454756659493 GO:0070325 lipoprotein particle receptor binding 3/816 31/18639 0.0967741935483871 2.21050759013283 0.152607413078767 0.569454756659493 GO:0003688 DNA replication origin binding 2/816 16/18639 0.125 2.85523897058824 0.153474278849957 0.569454756659493 GO:0005521 lamin binding 2/816 16/18639 0.125 2.85523897058824 0.153474278849957 0.569454756659493 GO:0008142 oxysterol binding 2/816 16/18639 0.125 2.85523897058824 0.153474278849957 0.569454756659493 GO:0015923 mannosidase activity 2/816 16/18639 0.125 2.85523897058824 0.153474278849957 0.569454756659493 GO:0030275 LRR domain binding 2/816 16/18639 0.125 2.85523897058824 0.153474278849957 0.569454756659493 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/816 16/18639 0.125 2.85523897058824 0.153474278849957 0.569454756659493 GO:0034450 ubiquitin-ubiquitin ligase activity 2/816 16/18639 0.125 2.85523897058824 0.153474278849957 0.569454756659493 GO:0055102 lipase inhibitor activity 2/816 16/18639 0.125 2.85523897058824 0.153474278849957 0.569454756659493 GO:0070411 I-SMAD binding 2/816 16/18639 0.125 2.85523897058824 0.153474278849957 0.569454756659493 GO:0097027 ubiquitin-protein transferase activator activity 2/816 16/18639 0.125 2.85523897058824 0.153474278849957 0.569454756659493 GO:0008378 galactosyltransferase activity 3/816 32/18639 0.09375 2.14142922794118 0.163261352474587 0.596555740410942 GO:0030515 snoRNA binding 3/816 32/18639 0.09375 2.14142922794118 0.163261352474587 0.596555740410942 GO:0042910 xenobiotic transmembrane transporter activity 3/816 32/18639 0.09375 2.14142922794118 0.163261352474587 0.596555740410942 GO:0043425 bHLH transcription factor binding 3/816 32/18639 0.09375 2.14142922794118 0.163261352474587 0.596555740410942 GO:0004659 prenyltransferase activity 2/816 17/18639 0.117647058823529 2.68728373702422 0.169145616034435 0.604271141297739 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/816 17/18639 0.117647058823529 2.68728373702422 0.169145616034435 0.604271141297739 GO:0016018 cyclosporin A binding 2/816 17/18639 0.117647058823529 2.68728373702422 0.169145616034435 0.604271141297739 GO:0017110 nucleoside diphosphate phosphatase activity 2/816 17/18639 0.117647058823529 2.68728373702422 0.169145616034435 0.604271141297739 GO:0030548 acetylcholine receptor regulator activity 2/816 17/18639 0.117647058823529 2.68728373702422 0.169145616034435 0.604271141297739 GO:0070492 oligosaccharide binding 2/816 17/18639 0.117647058823529 2.68728373702422 0.169145616034435 0.604271141297739 GO:0019956 chemokine binding 3/816 33/18639 0.0909090909090909 2.07653743315508 0.174129015761692 0.619770311655503 GO:0005539 glycosaminoglycan binding 14/816 242/18639 0.0578512396694215 1.32143291200778 0.176616262582724 0.626303425616229 GO:0003746 translation elongation factor activity 2/816 18/18639 0.111111111111111 2.53799019607843 0.185068576557875 0.642061018310895 GO:0008525 phosphatidylcholine transporter activity 2/816 18/18639 0.111111111111111 2.53799019607843 0.185068576557875 0.642061018310895 GO:0031690 adrenergic receptor binding 2/816 18/18639 0.111111111111111 2.53799019607843 0.185068576557875 0.642061018310895 GO:0034185 apolipoprotein binding 2/816 18/18639 0.111111111111111 2.53799019607843 0.185068576557875 0.642061018310895 GO:0070628 proteasome binding 2/816 18/18639 0.111111111111111 2.53799019607843 0.185068576557875 0.642061018310895 GO:0099602 neurotransmitter receptor regulator activity 2/816 18/18639 0.111111111111111 2.53799019607843 0.185068576557875 0.642061018310895 GO:0015293 symporter activity 9/816 146/18639 0.0616438356164384 1.40806305398872 0.19074869456184 0.657992703428564 GO:0008028 monocarboxylic acid transmembrane transporter activity 5/816 70/18639 0.0714285714285714 1.63156512605042 0.191714835546304 0.657992703428564 GO:0097110 scaffold protein binding 5/816 70/18639 0.0714285714285714 1.63156512605042 0.191714835546304 0.657992703428564 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 19/816 349/18639 0.0544412607449857 1.24354247429631 0.194219806233069 0.664217913843341 GO:0005154 epidermal growth factor receptor binding 3/816 35/18639 0.0857142857142857 1.9578781512605 0.196433408003293 0.669406046422568 GO:0043395 heparan sulfate proteoglycan binding 2/816 19/18639 0.105263157894737 2.40441176470588 0.201191179579562 0.679076103023496 GO:0050145 nucleoside monophosphate kinase activity 2/816 19/18639 0.105263157894737 2.40441176470588 0.201191179579562 0.679076103023496 GO:0005246 calcium channel regulator activity 4/816 53/18639 0.0754716981132075 1.72391786903441 0.201390935860246 0.679076103023496 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 8/816 130/18639 0.0615384615384615 1.40565610859729 0.210248064811197 0.706462903089371 GO:0000339 RNA cap binding 2/816 20/18639 0.1 2.28419117647059 0.21746550324193 0.718159273592766 GO:0015095 magnesium ion transmembrane transporter activity 2/816 20/18639 0.1 2.28419117647059 0.21746550324193 0.718159273592766 GO:0030742 GTP-dependent protein binding 2/816 20/18639 0.1 2.28419117647059 0.21746550324193 0.718159273592766 GO:0042288 MHC class I protein binding 2/816 20/18639 0.1 2.28419117647059 0.21746550324193 0.718159273592766 GO:0061608 nuclear import signal receptor activity 2/816 20/18639 0.1 2.28419117647059 0.21746550324193 0.718159273592766 GO:0023023 MHC protein complex binding 3/816 37/18639 0.0810810810810811 1.85204689984102 0.219379221687598 0.719533897753523 GO:0042805 actinin binding 3/816 37/18639 0.0810810810810811 1.85204689984102 0.219379221687598 0.719533897753523 GO:0005179 hormone activity 8/816 132/18639 0.0606060606060606 1.38435828877005 0.221904262184703 0.724414170933259 GO:0008201 heparin binding 10/816 172/18639 0.0581395348837209 1.32801812585499 0.22237479752894 0.724414170933259 GO:0001846 opsonin binding 2/816 21/18639 0.0952380952380952 2.17542016806723 0.233847429616429 0.751596588165179 GO:0051428 peptide hormone receptor binding 2/816 21/18639 0.0952380952380952 2.17542016806723 0.233847429616429 0.751596588165179 GO:0070182 DNA polymerase binding 2/816 21/18639 0.0952380952380952 2.17542016806723 0.233847429616429 0.751596588165179 GO:0072542 protein phosphatase activator activity 2/816 21/18639 0.0952380952380952 2.17542016806723 0.233847429616429 0.751596588165179 GO:0004252 serine-type endopeptidase activity 10/816 176/18639 0.0568181818181818 1.29783589572192 0.243262218935592 0.779249974657014 GO:0015294 solute:monoatomic cation symporter activity 7/816 116/18639 0.0603448275862069 1.37839122718053 0.245788796938376 0.782471875842399 GO:0140789 histone phosphatase activity 8/816 136/18639 0.0588235294117647 1.34364186851211 0.245896468787101 0.782471875842399 GO:0061980 regulatory RNA binding 4/816 58/18639 0.0689655172413793 1.57530425963489 0.248372699679121 0.787743116804078 GO:0005319 lipid transporter activity 10/816 178/18639 0.0561797752808989 1.2832534699273 0.253961223437011 0.799908097416476 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/816 40/18639 0.075 1.71314338235294 0.254705387939065 0.799908097416476 GO:0071855 neuropeptide receptor binding 3/816 40/18639 0.075 1.71314338235294 0.254705387939065 0.799908097416476 GO:0030295 protein kinase activator activity 8/816 139/18639 0.0575539568345324 1.31464240372408 0.264422487194499 0.821701845345469 GO:0005158 insulin receptor binding 2/816 23/18639 0.0869565217391304 1.98625319693095 0.266775208894679 0.821701845345469 GO:0005283 amino acid:sodium symporter activity 2/816 23/18639 0.0869565217391304 1.98625319693095 0.266775208894679 0.821701845345469 GO:0008171 O-methyltransferase activity 2/816 23/18639 0.0869565217391304 1.98625319693095 0.266775208894679 0.821701845345469 GO:0016493 C-C chemokine receptor activity 2/816 23/18639 0.0869565217391304 1.98625319693095 0.266775208894679 0.821701845345469 GO:0099186 structural constituent of postsynapse 2/816 23/18639 0.0869565217391304 1.98625319693095 0.266775208894679 0.821701845345469 GO:0016836 hydro-lyase activity 4/816 61/18639 0.0655737704918033 1.49783027965284 0.277604470320994 0.831840853109378 GO:0019894 kinesin binding 3/816 42/18639 0.0714285714285714 1.63156512605042 0.278675689166986 0.831840853109378 GO:0051879 Hsp90 protein binding 3/816 42/18639 0.0714285714285714 1.63156512605042 0.278675689166986 0.831840853109378 GO:0030971 receptor tyrosine kinase binding 5/816 81/18639 0.0617283950617284 1.40999455337691 0.281091769177748 0.831840853109378 GO:0015149 hexose transmembrane transporter activity 2/816 24/18639 0.0833333333333333 1.90349264705882 0.283249748596304 0.831840853109378 GO:0019957 C-C chemokine binding 2/816 24/18639 0.0833333333333333 1.90349264705882 0.283249748596304 0.831840853109378 GO:0055056 D-glucose transmembrane transporter activity 2/816 24/18639 0.0833333333333333 1.90349264705882 0.283249748596304 0.831840853109378 GO:0070840 dynein complex binding 2/816 24/18639 0.0833333333333333 1.90349264705882 0.283249748596304 0.831840853109378 GO:0008237 metallopeptidase activity 10/816 184/18639 0.0543478260869565 1.24140824808184 0.286951416424242 0.831840853109378 GO:0015171 amino acid transmembrane transporter activity 6/816 102/18639 0.0588235294117647 1.34364186851211 0.288817777471136 0.831840853109378 GO:0004712 protein serine/threonine/tyrosine kinase activity 3/816 43/18639 0.0697674418604651 1.59362175102599 0.290741909737832 0.831840853109378 GO:0008200 ion channel inhibitor activity 3/816 43/18639 0.0697674418604651 1.59362175102599 0.290741909737832 0.831840853109378 GO:0005253 monoatomic anion channel activity 6/816 103/18639 0.058252427184466 1.33059680182753 0.296461657615134 0.831840853109378 GO:0001848 complement binding 2/816 25/18639 0.08 1.82735294117647 0.299688849250257 0.831840853109378 GO:0005537 D-mannose binding 2/816 25/18639 0.08 1.82735294117647 0.299688849250257 0.831840853109378 GO:0008139 nuclear localization sequence binding 2/816 25/18639 0.08 1.82735294117647 0.299688849250257 0.831840853109378 GO:0019211 phosphatase activator activity 2/816 25/18639 0.08 1.82735294117647 0.299688849250257 0.831840853109378 GO:0016248 channel inhibitor activity 3/816 44/18639 0.0681818181818182 1.55740307486631 0.302843469498505 0.831840853109378 GO:0046943 carboxylic acid transmembrane transporter activity 10/816 188/18639 0.0531914893617021 1.21499530663329 0.309578436860239 0.831840853109378 GO:0141110 transporter inhibitor activity 3/816 45/18639 0.0666666666666667 1.52279411764706 0.31496700138653 0.831840853109378 GO:0005342 organic acid transmembrane transporter activity 10/816 189/18639 0.0529100529100529 1.20856676003735 0.315301433054111 0.831840853109378 GO:0016247 channel regulator activity 9/816 168/18639 0.0535714285714286 1.22367384453782 0.315772082177695 0.831840853109378 GO:0001637 G protein-coupled chemoattractant receptor activity 2/816 26/18639 0.0769230769230769 1.75707013574661 0.316064068151374 0.831840853109378 GO:0004950 chemokine receptor activity 2/816 26/18639 0.0769230769230769 1.75707013574661 0.316064068151374 0.831840853109378 GO:0015145 monosaccharide transmembrane transporter activity 2/816 26/18639 0.0769230769230769 1.75707013574661 0.316064068151374 0.831840853109378 GO:0050681 nuclear androgen receptor binding 2/816 26/18639 0.0769230769230769 1.75707013574661 0.316064068151374 0.831840853109378 GO:0070006 metalloaminopeptidase activity 2/816 26/18639 0.0769230769230769 1.75707013574661 0.316064068151374 0.831840853109378 GO:0070412 R-SMAD binding 2/816 26/18639 0.0769230769230769 1.75707013574661 0.316064068151374 0.831840853109378 GO:0097602 cullin family protein binding 2/816 26/18639 0.0769230769230769 1.75707013574661 0.316064068151374 0.831840853109378 GO:0120014 phospholipid transfer activity 2/816 26/18639 0.0769230769230769 1.75707013574661 0.316064068151374 0.831840853109378 GO:0042826 histone deacetylase binding 7/816 127/18639 0.0551181102362205 1.25900301065308 0.321539781097468 0.831840853109378 GO:0019209 kinase activator activity 8/816 148/18639 0.0540540540540541 1.23469793322735 0.322137001441302 0.831840853109378 GO:0141108 transporter regulator activity 9/816 170/18639 0.0529411764705882 1.2092776816609 0.328010263481994 0.831840853109378 GO:0001671 ATPase activator activity 2/816 27/18639 0.0740740740740741 1.69199346405229 0.332349514993357 0.831840853109378 GO:0008395 steroid hydroxylase activity 2/816 27/18639 0.0740740740740741 1.69199346405229 0.332349514993357 0.831840853109378 GO:0019842 vitamin binding 8/816 150/18639 0.0533333333333333 1.21823529411765 0.335288888027421 0.831840853109378 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/816 67/18639 0.0597014925373134 1.36369622475856 0.337384301825997 0.831840853109378 GO:0001784 phosphotyrosine residue binding 3/816 47/18639 0.0638297872340425 1.45799436795995 0.339229207799926 0.831840853109378 GO:0140359 ABC-type transporter activity 3/816 47/18639 0.0638297872340425 1.45799436795995 0.339229207799926 0.831840853109378 GO:0030246 carbohydrate binding 14/816 280/18639 0.05 1.14209558823529 0.343505959714291 0.831840853109378 GO:0008236 serine-type peptidase activity 10/816 194/18639 0.0515463917525773 1.17741813220133 0.344242256059942 0.831840853109378 GO:0005548 phospholipid transporter activity 4/816 68/18639 0.0588235294117647 1.34364186851211 0.347429017935554 0.831840853109378 GO:0046625 sphingolipid binding 2/816 28/18639 0.0714285714285714 1.63156512605042 0.348521683358942 0.831840853109378 GO:0051119 sugar transmembrane transporter activity 2/816 28/18639 0.0714285714285714 1.63156512605042 0.348521683358942 0.831840853109378 GO:0051393 alpha-actinin binding 2/816 28/18639 0.0714285714285714 1.63156512605042 0.348521683358942 0.831840853109378 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 5/816 89/18639 0.0561797752808989 1.2832534699273 0.35035972475581 0.831840853109378 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 5/816 89/18639 0.0561797752808989 1.2832534699273 0.35035972475581 0.831840853109378 GO:0004222 metalloendopeptidase activity 6/816 110/18639 0.0545454545454545 1.24592245989305 0.350858494433815 0.831840853109378 GO:0140693 molecular condensate scaffold activity 3/816 48/18639 0.0625 1.42761948529412 0.351343849625298 0.831840853109378 GO:0046982 protein heterodimerization activity 18/816 369/18639 0.0487804878048781 1.11423959827834 0.352470262968452 0.831840853109378 GO:0004721 phosphoprotein phosphatase activity 9/816 175/18639 0.0514285714285714 1.1747268907563 0.358954408869746 0.831840853109378 GO:0140793 histone H2AXY142 phosphatase activity 5/816 90/18639 0.0555555555555556 1.26899509803922 0.359119055501158 0.831840853109378 GO:0004090 carbonyl reductase (NADPH) activity 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0004955 prostaglandin receptor activity 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0005337 nucleoside transmembrane transporter activity 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0015187 glycine transmembrane transporter activity 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0016868 intramolecular phosphotransferase activity 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0032052 bile acid binding 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0032356 oxidized DNA binding 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0033204 ribonuclease P RNA binding 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0042975 peroxisome proliferator activated receptor binding 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0097177 mitochondrial ribosome binding 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0098505 G-rich strand telomeric DNA binding 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0140940 histone H2A methyltransferase activity 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0141109 transporter activator activity 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:1990259 histone H2AQ104 methyltransferase activity 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:1990757 ubiquitin ligase activator activity 1/816 10/18639 0.1 2.28419117647059 0.360951284467677 0.831840853109378 GO:0001222 transcription corepressor binding 3/816 49/18639 0.0612244897959184 1.3984843937575 0.363432397512928 0.831840853109378 GO:0016763 pentosyltransferase activity 3/816 49/18639 0.0612244897959184 1.3984843937575 0.363432397512928 0.831840853109378 GO:0060590 ATPase regulator activity 3/816 49/18639 0.0612244897959184 1.3984843937575 0.363432397512928 0.831840853109378 GO:0004629 phospholipase C activity 2/816 29/18639 0.0689655172413793 1.57530425963489 0.364559292043701 0.831840853109378 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/816 29/18639 0.0689655172413793 1.57530425963489 0.364559292043701 0.831840853109378 GO:0005416 amino acid:monoatomic cation symporter activity 2/816 29/18639 0.0689655172413793 1.57530425963489 0.364559292043701 0.831840853109378 GO:0016417 S-acyltransferase activity 2/816 29/18639 0.0689655172413793 1.57530425963489 0.364559292043701 0.831840853109378 GO:0043236 laminin binding 2/816 29/18639 0.0689655172413793 1.57530425963489 0.364559292043701 0.831840853109378 GO:0097472 cyclin-dependent protein kinase activity 2/816 29/18639 0.0689655172413793 1.57530425963489 0.364559292043701 0.831840853109378 GO:0017171 serine hydrolase activity 10/816 198/18639 0.0505050505050505 1.15363190730838 0.367699912514228 0.831840853109378 GO:0072341 modified amino acid binding 5/816 91/18639 0.0549450549450549 1.25505009696186 0.367885008400573 0.831840853109378 GO:0048020 CCR chemokine receptor binding 3/816 50/18639 0.06 1.37051470588235 0.375484184305326 0.831840853109378 GO:0015291 secondary active transmembrane transporter activity 14/816 287/18639 0.0487804878048781 1.11423959827834 0.377695844580266 0.831840853109378 GO:0001965 G-protein alpha-subunit binding 2/816 30/18639 0.0666666666666667 1.52279411764706 0.380443135677049 0.831840853109378 GO:0008106 alcohol dehydrogenase (NADP+) activity 2/816 30/18639 0.0666666666666667 1.52279411764706 0.380443135677049 0.831840853109378 GO:0098918 structural constituent of synapse 2/816 30/18639 0.0666666666666667 1.52279411764706 0.380443135677049 0.831840853109378 GO:0051219 phosphoprotein binding 5/816 93/18639 0.0537634408602151 1.22805977229602 0.385418884457728 0.831840853109378 GO:0016779 nucleotidyltransferase activity 7/816 136/18639 0.0514705882352941 1.1756866349481 0.386054625871959 0.831840853109378 GO:0019838 growth factor binding 7/816 136/18639 0.0514705882352941 1.1756866349481 0.386054625871959 0.831840853109378 GO:0016830 carbon-carbon lyase activity 3/816 51/18639 0.0588235294117647 1.34364186851211 0.387489075303904 0.831840853109378 GO:0002162 dystroglycan binding 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0004016 adenylate cyclase activity 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0004523 RNA-DNA hybrid ribonuclease activity 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0004954 prostanoid receptor activity 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0005225 volume-sensitive anion channel activity 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0008199 ferric iron binding 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0008271 secondary active sulfate transmembrane transporter activity 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0008432 JUN kinase binding 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0008526 phosphatidylinositol transfer activity 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0015217 ADP transmembrane transporter activity 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0016594 glycine binding 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0032794 GTPase activating protein binding 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0034713 type I transforming growth factor beta receptor binding 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0043522 leucine zipper domain binding 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0047676 arachidonate-CoA ligase activity 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0048185 activin binding 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0048407 platelet-derived growth factor binding 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0050998 nitric-oxide synthase binding 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0070697 activin receptor binding 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0140031 phosphorylation-dependent protein binding 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0140537 transcription regulator activator activity 1/816 11/18639 0.0909090909090909 2.07653743315508 0.388943326545855 0.831840853109378 GO:0016410 N-acyltransferase activity 5/816 94/18639 0.0531914893617021 1.21499530663329 0.394178103641353 0.831840853109378 GO:0042562 hormone binding 5/816 94/18639 0.0531914893617021 1.21499530663329 0.394178103641353 0.831840853109378 GO:0072349 modified amino acid transmembrane transporter activity 2/816 31/18639 0.0645161290322581 1.47367172675522 0.396155944132103 0.831840853109378 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 3/816 52/18639 0.0576923076923077 1.31780260180995 0.399437461812301 0.831840853109378 GO:0003714 transcription corepressor activity 10/816 204/18639 0.0490196078431373 1.11970155709343 0.403181855677902 0.831840853109378 GO:1990782 protein tyrosine kinase binding 6/816 117/18639 0.0512820512820513 1.17138009049774 0.405964140302791 0.831840853109378 GO:0042277 peptide binding 12/816 249/18639 0.0481927710843374 1.1008150248051 0.408511557615443 0.831840853109378 GO:0005544 calcium-dependent phospholipid binding 3/816 53/18639 0.0566037735849057 1.2929384017758 0.411320253369423 0.831840853109378 GO:0140296 general transcription initiation factor binding 3/816 53/18639 0.0566037735849057 1.2929384017758 0.411320253369423 0.831840853109378 GO:0016407 acetyltransferase activity 5/816 96/18639 0.0520833333333333 1.18968290441176 0.411660109506015 0.831840853109378 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/816 32/18639 0.0625 1.42761948529412 0.411682250242604 0.831840853109378 GO:0051059 NF-kappaB binding 2/816 32/18639 0.0625 1.42761948529412 0.411682250242604 0.831840853109378 GO:0070717 poly-purine tract binding 2/816 32/18639 0.0625 1.42761948529412 0.411682250242604 0.831840853109378 GO:0071813 lipoprotein particle binding 2/816 32/18639 0.0625 1.42761948529412 0.411682250242604 0.831840853109378 GO:0071814 protein-lipid complex binding 2/816 32/18639 0.0625 1.42761948529412 0.411682250242604 0.831840853109378 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0003720 telomerase activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0003995 acyl-CoA dehydrogenase activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0004032 aldose reductase (NADPH) activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0004526 ribonuclease P activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0004875 complement receptor activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0005095 GTPase inhibitor activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0005165 neurotrophin receptor binding 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0008179 adenylate cyclase binding 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0008603 cAMP-dependent protein kinase regulator activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0016801 hydrolase activity, acting on ether bonds 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0016803 ether hydrolase activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0016840 carbon-nitrogen lyase activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0017166 vinculin binding 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0031543 peptidyl-proline dioxygenase activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0035197 siRNA binding 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0035259 nuclear glucocorticoid receptor binding 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0036009 protein-glutamine N-methyltransferase activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0042301 phosphate ion binding 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0043047 single-stranded telomeric DNA binding 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0045295 gamma-catenin binding 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0097677 STAT family protein binding 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:1990817 poly(A) RNA polymerase activity 1/816 12/18639 0.0833333333333333 1.90349264705882 0.415710679215952 0.831840853109378 GO:0015485 cholesterol binding 3/816 54/18639 0.0555555555555556 1.26899509803922 0.423128868836127 0.831840853109378 GO:0050661 NADP binding 3/816 54/18639 0.0555555555555556 1.26899509803922 0.423128868836127 0.831840853109378 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/816 33/18639 0.0606060606060606 1.38435828877005 0.427008265370404 0.831840853109378 GO:0140311 protein sequestering activity 2/816 33/18639 0.0606060606060606 1.38435828877005 0.427008265370404 0.831840853109378 GO:0140416 transcription regulator inhibitor activity 2/816 33/18639 0.0606060606060606 1.38435828877005 0.427008265370404 0.831840853109378 GO:0001664 G protein-coupled receptor binding 14/816 297/18639 0.0471380471380471 1.07672311348782 0.427168811217614 0.831840853109378 GO:0017022 myosin binding 4/816 76/18639 0.0526315789473684 1.20220588235294 0.427395012885838 0.831840853109378 GO:0005126 cytokine receptor binding 13/816 275/18639 0.0472727272727273 1.07979946524064 0.428602903045034 0.831840853109378 GO:0004725 protein tyrosine phosphatase activity 5/816 98/18639 0.0510204081632653 1.16540366146459 0.429066784819739 0.831840853109378 GO:0042626 ATPase-coupled transmembrane transporter activity 5/816 98/18639 0.0510204081632653 1.16540366146459 0.429066784819739 0.831840853109378 GO:0015103 inorganic anion transmembrane transporter activity 8/816 165/18639 0.0484848484848485 1.10748663101604 0.435406817557169 0.831840853109378 GO:0003964 RNA-directed DNA polymerase activity 1/816 13/18639 0.0769230769230769 1.75707013574661 0.441306861411678 0.831840853109378 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/816 13/18639 0.0769230769230769 1.75707013574661 0.441306861411678 0.831840853109378 GO:0005542 folic acid binding 1/816 13/18639 0.0769230769230769 1.75707013574661 0.441306861411678 0.831840853109378 GO:0008035 high-density lipoprotein particle binding 1/816 13/18639 0.0769230769230769 1.75707013574661 0.441306861411678 0.831840853109378 GO:0030955 potassium ion binding 1/816 13/18639 0.0769230769230769 1.75707013574661 0.441306861411678 0.831840853109378 GO:0031994 insulin-like growth factor I binding 1/816 13/18639 0.0769230769230769 1.75707013574661 0.441306861411678 0.831840853109378 GO:0035673 oligopeptide transmembrane transporter activity 1/816 13/18639 0.0769230769230769 1.75707013574661 0.441306861411678 0.831840853109378 GO:0039706 co-receptor binding 1/816 13/18639 0.0769230769230769 1.75707013574661 0.441306861411678 0.831840853109378 GO:0045159 myosin II binding 1/816 13/18639 0.0769230769230769 1.75707013574661 0.441306861411678 0.831840853109378 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/816 13/18639 0.0769230769230769 1.75707013574661 0.441306861411678 0.831840853109378 GO:0061459 L-arginine transmembrane transporter activity 1/816 13/18639 0.0769230769230769 1.75707013574661 0.441306861411678 0.831840853109378 GO:0140666 annealing activity 1/816 13/18639 0.0769230769230769 1.75707013574661 0.441306861411678 0.831840853109378 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/816 13/18639 0.0769230769230769 1.75707013574661 0.441306861411678 0.831840853109378 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/816 34/18639 0.0588235294117647 1.34364186851211 0.442121762390983 0.831840853109378 GO:0016831 carboxy-lyase activity 2/816 34/18639 0.0588235294117647 1.34364186851211 0.442121762390983 0.831840853109378 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 2/816 34/18639 0.0588235294117647 1.34364186851211 0.442121762390983 0.831840853109378 GO:0051427 hormone receptor binding 2/816 34/18639 0.0588235294117647 1.34364186851211 0.442121762390983 0.831840853109378 GO:0019903 protein phosphatase binding 7/816 144/18639 0.0486111111111111 1.11037071078431 0.443673151585157 0.831840853109378 GO:0030170 pyridoxal phosphate binding 3/816 56/18639 0.0535714285714286 1.22367384453782 0.446491733238424 0.831840853109378 GO:0170055 lipid transmembrane transporter activity 3/816 56/18639 0.0535714285714286 1.22367384453782 0.446491733238424 0.831840853109378 GO:0015370 solute:sodium symporter activity 4/816 79/18639 0.0506329113924051 1.15655249441549 0.456812451974283 0.831840853109378 GO:0046332 SMAD binding 4/816 79/18639 0.0506329113924051 1.15655249441549 0.456812451974283 0.831840853109378 GO:0005343 organic acid:sodium symporter activity 2/816 35/18639 0.0571428571428571 1.30525210084034 0.457011965687207 0.831840853109378 GO:0016229 steroid dehydrogenase activity 2/816 35/18639 0.0571428571428571 1.30525210084034 0.457011965687207 0.831840853109378 GO:0016504 peptidase activator activity 3/816 57/18639 0.0526315789473684 1.20220588235294 0.45803127315987 0.831840853109378 GO:0070279 vitamin B6 binding 3/816 57/18639 0.0526315789473684 1.20220588235294 0.45803127315987 0.831840853109378 GO:0005161 platelet-derived growth factor receptor binding 1/816 14/18639 0.0714285714285714 1.63156512605042 0.46578305603683 0.831840853109378 GO:0005347 ATP transmembrane transporter activity 1/816 14/18639 0.0714285714285714 1.63156512605042 0.46578305603683 0.831840853109378 GO:0008494 translation activator activity 1/816 14/18639 0.0714285714285714 1.63156512605042 0.46578305603683 0.831840853109378 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/816 14/18639 0.0714285714285714 1.63156512605042 0.46578305603683 0.831840853109378 GO:0034236 protein kinase A catalytic subunit binding 1/816 14/18639 0.0714285714285714 1.63156512605042 0.46578305603683 0.831840853109378 GO:0070742 C2H2 zinc finger domain binding 1/816 14/18639 0.0714285714285714 1.63156512605042 0.46578305603683 0.831840853109378 GO:0071933 Arp2/3 complex binding 1/816 14/18639 0.0714285714285714 1.63156512605042 0.46578305603683 0.831840853109378 GO:0098847 sequence-specific single stranded DNA binding 1/816 14/18639 0.0714285714285714 1.63156512605042 0.46578305603683 0.831840853109378 GO:1901474 azole transmembrane transporter activity 1/816 14/18639 0.0714285714285714 1.63156512605042 0.46578305603683 0.831840853109378 GO:0004033 aldo-keto reductase (NADPH) activity 2/816 36/18639 0.0555555555555556 1.26899509803922 0.471669447763157 0.831840853109378 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/816 36/18639 0.0555555555555556 1.26899509803922 0.471669447763157 0.831840853109378 GO:0015101 organic cation transmembrane transporter activity 4/816 81/18639 0.0493827160493827 1.12799564270152 0.476139392831151 0.831840853109378 GO:0033192 calmodulin-dependent protein phosphatase activity 4/816 81/18639 0.0493827160493827 1.12799564270152 0.476139392831151 0.831840853109378 GO:0140791 histone H2AXS140 phosphatase activity 4/816 81/18639 0.0493827160493827 1.12799564270152 0.476139392831151 0.831840853109378 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 4/816 81/18639 0.0493827160493827 1.12799564270152 0.476139392831151 0.831840853109378 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 4/816 81/18639 0.0493827160493827 1.12799564270152 0.476139392831151 0.831840853109378 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 4/816 81/18639 0.0493827160493827 1.12799564270152 0.476139392831151 0.831840853109378 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 4/816 81/18639 0.0493827160493827 1.12799564270152 0.476139392831151 0.831840853109378 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 4/816 81/18639 0.0493827160493827 1.12799564270152 0.476139392831151 0.831840853109378 GO:1990439 MAP kinase serine/threonine phosphatase activity 4/816 81/18639 0.0493827160493827 1.12799564270152 0.476139392831151 0.831840853109378 GO:0003730 mRNA 3'-UTR binding 12/816 262/18639 0.0458015267175573 1.04619443197126 0.478277701553962 0.831840853109378 GO:0008509 monoatomic anion transmembrane transporter activity 7/816 149/18639 0.0469798657718121 1.07310994867746 0.479255545134654 0.831840853109378 GO:0001786 phosphatidylserine binding 3/816 59/18639 0.0508474576271186 1.16145314057827 0.480793301315525 0.831840853109378 GO:0004879 nuclear receptor activity 3/816 59/18639 0.0508474576271186 1.16145314057827 0.480793301315525 0.831840853109378 GO:0036002 pre-mRNA binding 3/816 59/18639 0.0508474576271186 1.16145314057827 0.480793301315525 0.831840853109378 GO:0070063 RNA polymerase binding 3/816 59/18639 0.0508474576271186 1.16145314057827 0.480793301315525 0.831840853109378 GO:0070888 E-box binding 3/816 59/18639 0.0508474576271186 1.16145314057827 0.480793301315525 0.831840853109378 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 4/816 82/18639 0.0487804878048781 1.11423959827834 0.485704181060855 0.831840853109378 GO:0033549 MAP kinase phosphatase activity 4/816 82/18639 0.0487804878048781 1.11423959827834 0.485704181060855 0.831840853109378 GO:0022829 wide pore channel activity 2/816 37/18639 0.0540540540540541 1.23469793322735 0.486086032110332 0.831840853109378 GO:0030280 structural constituent of skin epidermis 2/816 37/18639 0.0540540540540541 1.23469793322735 0.486086032110332 0.831840853109378 GO:0000774 adenyl-nucleotide exchange factor activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0004089 carbonate dehydratase activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0004467 long-chain fatty acid-CoA ligase activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0004953 icosanoid receptor activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0005041 low-density lipoprotein particle receptor activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0008242 omega peptidase activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0015116 sulfate transmembrane transporter activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0015929 hexosaminidase activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0016846 carbon-sulfur lyase activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0031005 filamin binding 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0048531 beta-1,3-galactosyltransferase activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0050780 dopamine receptor binding 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0051371 muscle alpha-actinin binding 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0061578 K63-linked deubiquitinase activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0120283 protein serine/threonine kinase binding 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0140161 monocarboxylate:sodium symporter activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0140776 protein-containing complex destabilizing activity 1/816 15/18639 0.0666666666666667 1.52279411764706 0.489188211809928 0.831840853109378 GO:0031490 chromatin DNA binding 6/816 128/18639 0.046875 1.07071461397059 0.491398095046468 0.831840853109378 GO:0001098 basal transcription machinery binding 3/816 60/18639 0.05 1.14209558823529 0.492003831934154 0.831840853109378 GO:0001099 basal RNA polymerase II transcription machinery binding 3/816 60/18639 0.05 1.14209558823529 0.492003831934154 0.831840853109378 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 3/816 60/18639 0.05 1.14209558823529 0.492003831934154 0.831840853109378 GO:0098531 ligand-modulated transcription factor activity 3/816 60/18639 0.05 1.14209558823529 0.492003831934154 0.831840853109378 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 4/816 83/18639 0.0481927710843374 1.1008150248051 0.495197768526336 0.831840853109378 GO:0005254 chloride channel activity 4/816 83/18639 0.0481927710843374 1.1008150248051 0.495197768526336 0.831840853109378 GO:0016758 hexosyltransferase activity 9/816 197/18639 0.0456852791878173 1.04353911615408 0.496282810911845 0.831840853109378 GO:0000149 SNARE binding 5/816 106/18639 0.0471698113207547 1.0774486681465 0.497356166689263 0.831840853109378 GO:0004497 monooxygenase activity 5/816 106/18639 0.0471698113207547 1.0774486681465 0.497356166689263 0.831840853109378 GO:0005109 frizzled binding 2/816 38/18639 0.0526315789473684 1.20220588235294 0.500254701977968 0.831840853109378 GO:0005501 retinoid binding 2/816 38/18639 0.0526315789473684 1.20220588235294 0.500254701977968 0.831840853109378 GO:0019840 isoprenoid binding 2/816 38/18639 0.0526315789473684 1.20220588235294 0.500254701977968 0.831840853109378 GO:0042887 amide transmembrane transporter activity 2/816 38/18639 0.0526315789473684 1.20220588235294 0.500254701977968 0.831840853109378 GO:0043531 ADP binding 2/816 38/18639 0.0526315789473684 1.20220588235294 0.500254701977968 0.831840853109378 GO:0019905 syntaxin binding 3/816 61/18639 0.0491803278688525 1.12337270973963 0.503093454086559 0.831840853109378 GO:0017018 myosin phosphatase activity 4/816 84/18639 0.0476190476190476 1.08771008403361 0.504616352762543 0.831840853109378 GO:0016757 glycosyltransferase activity 12/816 267/18639 0.0449438202247191 1.02660277594184 0.504780209877746 0.831840853109378 GO:0003774 cytoskeletal motor activity 7/816 153/18639 0.0457516339869281 1.04505478662053 0.507272092443219 0.831840853109378 GO:0004175 endopeptidase activity 18/816 405/18639 0.0444444444444444 1.01519607843137 0.508244878073193 0.831840853109378 GO:0000062 fatty-acyl-CoA binding 1/816 16/18639 0.0625 1.42761948529412 0.511569140673925 0.831840853109378 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/816 16/18639 0.0625 1.42761948529412 0.511569140673925 0.831840853109378 GO:0004708 MAP kinase kinase activity 1/816 16/18639 0.0625 1.42761948529412 0.511569140673925 0.831840853109378 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/816 16/18639 0.0625 1.42761948529412 0.511569140673925 0.831840853109378 GO:0015378 sodium:chloride symporter activity 1/816 16/18639 0.0625 1.42761948529412 0.511569140673925 0.831840853109378 GO:0015562 efflux transmembrane transporter activity 1/816 16/18639 0.0625 1.42761948529412 0.511569140673925 0.831840853109378 GO:0016722 oxidoreductase activity, acting on metal ions 1/816 16/18639 0.0625 1.42761948529412 0.511569140673925 0.831840853109378 GO:0022858 alanine transmembrane transporter activity 1/816 16/18639 0.0625 1.42761948529412 0.511569140673925 0.831840853109378 GO:0043023 ribosomal large subunit binding 1/816 16/18639 0.0625 1.42761948529412 0.511569140673925 0.831840853109378 GO:0140328 floppase activity 1/816 16/18639 0.0625 1.42761948529412 0.511569140673925 0.831840853109378 GO:0015179 L-amino acid transmembrane transporter activity 3/816 62/18639 0.0483870967741935 1.10525379506641 0.514057247045413 0.834474686504463 GO:0051020 GTPase binding 14/816 315/18639 0.0444444444444444 1.01519607843137 0.515788804811506 0.835873594306674 GO:0005507 copper ion binding 3/816 63/18639 0.0476190476190476 1.08771008403361 0.524890688687862 0.838272924936664 GO:0004177 aminopeptidase activity 2/816 40/18639 0.05 1.14209558823529 0.527825521390258 0.838272924936664 GO:0015144 carbohydrate transmembrane transporter activity 2/816 40/18639 0.05 1.14209558823529 0.527825521390258 0.838272924936664 GO:0071949 FAD binding 2/816 40/18639 0.05 1.14209558823529 0.527825521390258 0.838272924936664 GO:0004549 tRNA-specific ribonuclease activity 1/816 17/18639 0.0588235294117647 1.34364186851211 0.532970610963893 0.838272924936664 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/816 17/18639 0.0588235294117647 1.34364186851211 0.532970610963893 0.838272924936664 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/816 17/18639 0.0588235294117647 1.34364186851211 0.532970610963893 0.838272924936664 GO:0005092 GDP-dissociation inhibitor activity 1/816 17/18639 0.0588235294117647 1.34364186851211 0.532970610963893 0.838272924936664 GO:0008429 phosphatidylethanolamine binding 1/816 17/18639 0.0588235294117647 1.34364186851211 0.532970610963893 0.838272924936664 GO:0019198 transmembrane receptor protein phosphatase activity 1/816 17/18639 0.0588235294117647 1.34364186851211 0.532970610963893 0.838272924936664 GO:0030169 low-density lipoprotein particle binding 1/816 17/18639 0.0588235294117647 1.34364186851211 0.532970610963893 0.838272924936664 GO:0031489 myosin V binding 1/816 17/18639 0.0588235294117647 1.34364186851211 0.532970610963893 0.838272924936664 GO:0032183 SUMO binding 1/816 17/18639 0.0588235294117647 1.34364186851211 0.532970610963893 0.838272924936664 GO:0036041 long-chain fatty acid binding 1/816 17/18639 0.0588235294117647 1.34364186851211 0.532970610963893 0.838272924936664 GO:0045236 CXCR chemokine receptor binding 1/816 17/18639 0.0588235294117647 1.34364186851211 0.532970610963893 0.838272924936664 GO:0070402 NADPH binding 1/816 17/18639 0.0588235294117647 1.34364186851211 0.532970610963893 0.838272924936664 GO:0070403 NAD+ binding 1/816 17/18639 0.0588235294117647 1.34364186851211 0.532970610963893 0.838272924936664 GO:1901567 fatty acid derivative binding 1/816 17/18639 0.0588235294117647 1.34364186851211 0.532970610963893 0.838272924936664 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 8/816 181/18639 0.0441988950276243 1.00958726031849 0.539925563600831 0.847086583674822 GO:0017080 sodium channel regulator activity 2/816 41/18639 0.0487804878048781 1.11423959827834 0.541218691338544 0.847086583674822 GO:0042287 MHC protein binding 2/816 41/18639 0.0487804878048781 1.11423959827834 0.541218691338544 0.847086583674822 GO:0002020 protease binding 6/816 136/18639 0.0441176470588235 1.00773140138408 0.550914160726816 0.851963233821086 GO:0008308 voltage-gated monoatomic anion channel activity 1/816 18/18639 0.0555555555555556 1.26899509803922 0.553435436517189 0.851963233821086 GO:0015373 monoatomic anion:sodium symporter activity 1/816 18/18639 0.0555555555555556 1.26899509803922 0.553435436517189 0.851963233821086 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/816 18/18639 0.0555555555555556 1.26899509803922 0.553435436517189 0.851963233821086 GO:0017128 phospholipid scramblase activity 1/816 18/18639 0.0555555555555556 1.26899509803922 0.553435436517189 0.851963233821086 GO:0030228 lipoprotein particle receptor activity 1/816 18/18639 0.0555555555555556 1.26899509803922 0.553435436517189 0.851963233821086 GO:0035615 clathrin adaptor activity 1/816 18/18639 0.0555555555555556 1.26899509803922 0.553435436517189 0.851963233821086 GO:0070064 proline-rich region binding 1/816 18/18639 0.0555555555555556 1.26899509803922 0.553435436517189 0.851963233821086 GO:1901611 phosphatidylglycerol binding 1/816 18/18639 0.0555555555555556 1.26899509803922 0.553435436517189 0.851963233821086 GO:1990381 ubiquitin-specific protease binding 1/816 18/18639 0.0555555555555556 1.26899509803922 0.553435436517189 0.851963233821086 GO:0048487 beta-tubulin binding 2/816 42/18639 0.0476190476190476 1.08771008403361 0.554345841447122 0.851963233821086 GO:0099106 ion channel regulator activity 7/816 160/18639 0.04375 0.999333639705882 0.554972928586889 0.851963233821086 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/816 43/18639 0.0465116279069767 1.06241450068399 0.567204569823184 0.853713148916876 GO:0048156 tau protein binding 2/816 43/18639 0.0465116279069767 1.06241450068399 0.567204569823184 0.853713148916876 GO:0017124 SH3 domain binding 5/816 115/18639 0.0434782608695652 0.993126598465473 0.570148555557384 0.853713148916876 GO:0035401 histone H3Y41 kinase activity 5/816 115/18639 0.0434782608695652 0.993126598465473 0.570148555557384 0.853713148916876 GO:0140801 histone H2AXY142 kinase activity 5/816 115/18639 0.0434782608695652 0.993126598465473 0.570148555557384 0.853713148916876 GO:0070851 growth factor receptor binding 6/816 139/18639 0.0431654676258993 0.98598180279306 0.572409685444945 0.853713148916876 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/816 19/18639 0.0526315789473684 1.20220588235294 0.573004561902613 0.853713148916876 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/816 19/18639 0.0526315789473684 1.20220588235294 0.573004561902613 0.853713148916876 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/816 19/18639 0.0526315789473684 1.20220588235294 0.573004561902613 0.853713148916876 GO:0005520 insulin-like growth factor binding 1/816 19/18639 0.0526315789473684 1.20220588235294 0.573004561902613 0.853713148916876 GO:0008574 plus-end-directed microtubule motor activity 1/816 19/18639 0.0526315789473684 1.20220588235294 0.573004561902613 0.853713148916876 GO:0015245 fatty acid transmembrane transporter activity 1/816 19/18639 0.0526315789473684 1.20220588235294 0.573004561902613 0.853713148916876 GO:0016918 retinal binding 1/816 19/18639 0.0526315789473684 1.20220588235294 0.573004561902613 0.853713148916876 GO:0031420 alkali metal ion binding 1/816 19/18639 0.0526315789473684 1.20220588235294 0.573004561902613 0.853713148916876 GO:0034987 immunoglobulin receptor binding 1/816 19/18639 0.0526315789473684 1.20220588235294 0.573004561902613 0.853713148916876 GO:0046624 sphingolipid transporter activity 1/816 19/18639 0.0526315789473684 1.20220588235294 0.573004561902613 0.853713148916876 GO:0070003 threonine-type peptidase activity 1/816 19/18639 0.0526315789473684 1.20220588235294 0.573004561902613 0.853713148916876 GO:0097001 ceramide binding 1/816 19/18639 0.0526315789473684 1.20220588235294 0.573004561902613 0.853713148916876 GO:0120227 acyl-CoA binding 1/816 19/18639 0.0526315789473684 1.20220588235294 0.573004561902613 0.853713148916876 GO:0008094 ATP-dependent activity, acting on DNA 9/816 210/18639 0.0428571428571429 0.978939075630252 0.573880014776589 0.853713148916876 GO:0032934 sterol binding 3/816 68/18639 0.0441176470588235 1.00773140138408 0.5769705017182 0.855661500233318 GO:1990841 promoter-specific chromatin binding 3/816 68/18639 0.0441176470588235 1.00773140138408 0.5769705017182 0.855661500233318 GO:0001046 core promoter sequence-specific DNA binding 2/816 44/18639 0.0454545454545455 1.03826871657754 0.57979319364817 0.857201937070601 GO:0001223 transcription coactivator binding 2/816 44/18639 0.0454545454545455 1.03826871657754 0.57979319364817 0.857201937070601 GO:0008080 N-acetyltransferase activity 3/816 69/18639 0.0434782608695652 0.993126598465473 0.586947439536725 0.860844741323934 GO:0003924 GTPase activity 14/816 331/18639 0.0422960725075529 0.966123156211125 0.591300736842357 0.860844741323934 GO:0005525 GTP binding 16/816 378/18639 0.0423280423280423 0.966853408029879 0.591414287242485 0.860844741323934 GO:0005326 neurotransmitter transmembrane transporter activity 1/816 20/18639 0.05 1.14209558823529 0.591717143937385 0.860844741323934 GO:0016004 phospholipase activator activity 1/816 20/18639 0.05 1.14209558823529 0.591717143937385 0.860844741323934 GO:0016408 C-acyltransferase activity 1/816 20/18639 0.05 1.14209558823529 0.591717143937385 0.860844741323934 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/816 20/18639 0.05 1.14209558823529 0.591717143937385 0.860844741323934 GO:0052745 inositol phosphate phosphatase activity 1/816 20/18639 0.05 1.14209558823529 0.591717143937385 0.860844741323934 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/816 45/18639 0.0444444444444444 1.01519607843137 0.592110690962664 0.860844741323934 GO:0008009 chemokine activity 2/816 45/18639 0.0444444444444444 1.01519607843137 0.592110690962664 0.860844741323934 GO:0140303 intramembrane lipid transporter activity 2/816 45/18639 0.0444444444444444 1.01519607843137 0.592110690962664 0.860844741323934 GO:0019902 phosphatase binding 8/816 190/18639 0.0421052631578947 0.961764705882353 0.595325688268919 0.864211459858658 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/816 46/18639 0.0434782608695652 0.993126598465473 0.604156646159999 0.869192604001408 GO:0030276 clathrin binding 2/816 46/18639 0.0434782608695652 0.993126598465473 0.604156646159999 0.869192604001408 GO:0032182 ubiquitin-like protein binding 5/816 120/18639 0.0416666666666667 0.951746323529412 0.608137873477851 0.869192604001408 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/816 21/18639 0.0476190476190476 1.08771008403361 0.609610629653433 0.869192604001408 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/816 21/18639 0.0476190476190476 1.08771008403361 0.609610629653433 0.869192604001408 GO:0009975 cyclase activity 1/816 21/18639 0.0476190476190476 1.08771008403361 0.609610629653433 0.869192604001408 GO:0015174 basic amino acid transmembrane transporter activity 1/816 21/18639 0.0476190476190476 1.08771008403361 0.609610629653433 0.869192604001408 GO:0019200 carbohydrate kinase activity 1/816 21/18639 0.0476190476190476 1.08771008403361 0.609610629653433 0.869192604001408 GO:0035613 RNA stem-loop binding 1/816 21/18639 0.0476190476190476 1.08771008403361 0.609610629653433 0.869192604001408 GO:0051010 microtubule plus-end binding 1/816 21/18639 0.0476190476190476 1.08771008403361 0.609610629653433 0.869192604001408 GO:0061891 calcium ion sensor activity 1/816 21/18639 0.0476190476190476 1.08771008403361 0.609610629653433 0.869192604001408 GO:0140312 cargo adaptor activity 1/816 21/18639 0.0476190476190476 1.08771008403361 0.609610629653433 0.869192604001408 GO:0140097 catalytic activity, acting on DNA 14/816 336/18639 0.0416666666666667 0.951746323529412 0.613865065253351 0.871777199427344 GO:0015108 chloride transmembrane transporter activity 5/816 121/18639 0.0413223140495868 0.943880651434127 0.615499722642441 0.871777199427344 GO:0061749 forked DNA-dependent helicase activity 2/816 47/18639 0.0425531914893617 0.971996245306633 0.615931198976003 0.871777199427344 GO:1990518 single-stranded 3'-5' DNA helicase activity 2/816 47/18639 0.0425531914893617 0.971996245306633 0.615931198976003 0.871777199427344 GO:0042379 chemokine receptor binding 3/816 72/18639 0.0416666666666667 0.951746323529412 0.615959124257198 0.871777199427344 GO:0005243 gap junction channel activity 1/816 22/18639 0.0454545454545455 1.03826871657754 0.626720830867462 0.875130670391407 GO:0008649 rRNA methyltransferase activity 1/816 22/18639 0.0454545454545455 1.03826871657754 0.626720830867462 0.875130670391407 GO:0015377 chloride:monoatomic cation symporter activity 1/816 22/18639 0.0454545454545455 1.03826871657754 0.626720830867462 0.875130670391407 GO:0016881 acid-amino acid ligase activity 1/816 22/18639 0.0454545454545455 1.03826871657754 0.626720830867462 0.875130670391407 GO:0031683 G-protein beta/gamma-subunit complex binding 1/816 22/18639 0.0454545454545455 1.03826871657754 0.626720830867462 0.875130670391407 GO:0140784 metal ion sensor activity 1/816 22/18639 0.0454545454545455 1.03826871657754 0.626720830867462 0.875130670391407 GO:0009378 four-way junction helicase activity 2/816 48/18639 0.0416666666666667 0.951746323529412 0.62743499677386 0.875130670391407 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/816 48/18639 0.0416666666666667 0.951746323529412 0.62743499677386 0.875130670391407 GO:0036121 double-stranded DNA helicase activity 2/816 48/18639 0.0416666666666667 0.951746323529412 0.62743499677386 0.875130670391407 GO:0043138 3'-5' DNA helicase activity 2/816 48/18639 0.0416666666666667 0.951746323529412 0.62743499677386 0.875130670391407 GO:0003678 DNA helicase activity 3/816 74/18639 0.0405405405405405 0.926023449920509 0.634519355090768 0.882859710968554 GO:0043130 ubiquitin binding 4/816 100/18639 0.04 0.913676470588235 0.642753583783486 0.882859710968554 GO:0000295 adenine nucleotide transmembrane transporter activity 1/816 23/18639 0.0434782608695652 0.993126598465473 0.643081995502589 0.882859710968554 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/816 23/18639 0.0434782608695652 0.993126598465473 0.643081995502589 0.882859710968554 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/816 23/18639 0.0434782608695652 0.993126598465473 0.643081995502589 0.882859710968554 GO:0005212 structural constituent of eye lens 1/816 23/18639 0.0434782608695652 0.993126598465473 0.643081995502589 0.882859710968554 GO:0016849 phosphorus-oxygen lyase activity 1/816 23/18639 0.0434782608695652 0.993126598465473 0.643081995502589 0.882859710968554 GO:0031681 G-protein beta-subunit binding 1/816 23/18639 0.0434782608695652 0.993126598465473 0.643081995502589 0.882859710968554 GO:0140102 catalytic activity, acting on a rRNA 1/816 23/18639 0.0434782608695652 0.993126598465473 0.643081995502589 0.882859710968554 GO:0140103 catalytic activity, acting on a glycoprotein 1/816 23/18639 0.0434782608695652 0.993126598465473 0.643081995502589 0.882859710968554 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/816 23/18639 0.0434782608695652 0.993126598465473 0.643081995502589 0.882859710968554 GO:0016791 phosphatase activity 11/816 273/18639 0.0402930402930403 0.920370071105365 0.653840015733679 0.891600743164156 GO:0019783 ubiquitin-like protein peptidase activity 5/816 127/18639 0.0393700787401575 0.8992878647522 0.657917825783789 0.891600743164156 GO:0004622 lysophospholipase activity 1/816 24/18639 0.0416666666666667 0.951746323529412 0.658726875802862 0.891600743164156 GO:0005315 phosphate transmembrane transporter activity 1/816 24/18639 0.0416666666666667 0.951746323529412 0.658726875802862 0.891600743164156 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/816 24/18639 0.0416666666666667 0.951746323529412 0.658726875802862 0.891600743164156 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/816 24/18639 0.0416666666666667 0.951746323529412 0.658726875802862 0.891600743164156 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/816 24/18639 0.0416666666666667 0.951746323529412 0.658726875802862 0.891600743164156 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/816 24/18639 0.0416666666666667 0.951746323529412 0.658726875802862 0.891600743164156 GO:0050699 WW domain binding 1/816 24/18639 0.0416666666666667 0.951746323529412 0.658726875802862 0.891600743164156 GO:0060229 lipase activator activity 1/816 24/18639 0.0416666666666667 0.951746323529412 0.658726875802862 0.891600743164156 GO:0030544 Hsp70 protein binding 2/816 51/18639 0.0392156862745098 0.89576124567474 0.660335031591465 0.892520345090573 GO:0004722 protein serine/threonine phosphatase activity 4/816 103/18639 0.0388349514563107 0.887064534551685 0.665646443324619 0.89519643984696 GO:0030159 signaling receptor complex adaptor activity 2/816 52/18639 0.0384615384615385 0.878535067873303 0.670770934382631 0.89519643984696 GO:0035591 signaling adaptor activity 5/816 129/18639 0.0387596899224806 0.885345417236662 0.671368240378794 0.89519643984696 GO:0003707 nuclear steroid receptor activity 1/816 25/18639 0.04 0.913676470588235 0.673686793575887 0.89519643984696 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/816 25/18639 0.04 0.913676470588235 0.673686793575887 0.89519643984696 GO:0015645 fatty acid ligase activity 1/816 25/18639 0.04 0.913676470588235 0.673686793575887 0.89519643984696 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/816 25/18639 0.04 0.913676470588235 0.673686793575887 0.89519643984696 GO:0017025 TBP-class protein binding 1/816 25/18639 0.04 0.913676470588235 0.673686793575887 0.89519643984696 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/816 25/18639 0.04 0.913676470588235 0.673686793575887 0.89519643984696 GO:0019707 protein-cysteine S-acyltransferase activity 1/816 25/18639 0.04 0.913676470588235 0.673686793575887 0.89519643984696 GO:0120515 fatty acid-CoA ligase activity 1/816 25/18639 0.04 0.913676470588235 0.673686793575887 0.89519643984696 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 9/816 229/18639 0.0393013100436681 0.897717056254816 0.676527705664469 0.89519643984696 GO:0004386 helicase activity 6/816 155/18639 0.0387096774193548 0.884203036053131 0.677526614552808 0.89519643984696 GO:0016298 lipase activity 5/816 130/18639 0.0384615384615385 0.878535067873303 0.677961258519171 0.89519643984696 GO:0019001 guanyl nucleotide binding 16/816 400/18639 0.04 0.913676470588235 0.680545587821014 0.89519643984696 GO:0032561 guanyl ribonucleotide binding 16/816 400/18639 0.04 0.913676470588235 0.680545587821014 0.89519643984696 GO:0017046 peptide hormone binding 2/816 53/18639 0.0377358490566038 0.861958934517203 0.680945470892953 0.89519643984696 GO:0034212 protein N-acetyltransferase activity 2/816 53/18639 0.0377358490566038 0.861958934517203 0.680945470892953 0.89519643984696 GO:0051018 protein kinase A binding 2/816 53/18639 0.0377358490566038 0.861958934517203 0.680945470892953 0.89519643984696 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/816 53/18639 0.0377358490566038 0.861958934517203 0.680945470892953 0.89519643984696 GO:0005160 transforming growth factor beta receptor binding 1/816 26/18639 0.0384615384615385 0.878535067873303 0.687991702592868 0.895880794297759 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/816 26/18639 0.0384615384615385 0.878535067873303 0.687991702592868 0.895880794297759 GO:0008143 poly(A) binding 1/816 26/18639 0.0384615384615385 0.878535067873303 0.687991702592868 0.895880794297759 GO:0015216 purine nucleotide transmembrane transporter activity 1/816 26/18639 0.0384615384615385 0.878535067873303 0.687991702592868 0.895880794297759 GO:0019865 immunoglobulin binding 1/816 26/18639 0.0384615384615385 0.878535067873303 0.687991702592868 0.895880794297759 GO:0034237 protein kinase A regulatory subunit binding 1/816 26/18639 0.0384615384615385 0.878535067873303 0.687991702592868 0.895880794297759 GO:0052742 phosphatidylinositol kinase activity 1/816 26/18639 0.0384615384615385 0.878535067873303 0.687991702592868 0.895880794297759 GO:0140658 ATP-dependent chromatin remodeler activity 6/816 158/18639 0.0379746835443038 0.867414370811616 0.695257707834426 0.903894247435993 GO:0005496 steroid binding 4/816 108/18639 0.037037037037037 0.845996732026144 0.701524909087928 0.903894247435993 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/816 27/18639 0.037037037037037 0.845996732026144 0.701670248269772 0.903894247435993 GO:0005044 scavenger receptor activity 1/816 27/18639 0.037037037037037 0.845996732026144 0.701670248269772 0.903894247435993 GO:0016405 CoA-ligase activity 1/816 27/18639 0.037037037037037 0.845996732026144 0.701670248269772 0.903894247435993 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/816 27/18639 0.037037037037037 0.845996732026144 0.701670248269772 0.903894247435993 GO:0035255 ionotropic glutamate receptor binding 1/816 27/18639 0.037037037037037 0.845996732026144 0.701670248269772 0.903894247435993 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/816 27/18639 0.037037037037037 0.845996732026144 0.701670248269772 0.903894247435993 GO:0004620 phospholipase activity 4/816 109/18639 0.036697247706422 0.838235294117647 0.70835698638908 0.911286564819151 GO:0001540 amyloid-beta binding 3/816 83/18639 0.036144578313253 0.825611268603827 0.710168554611263 0.912395696499229 GO:0016866 intramolecular transferase activity 1/816 28/18639 0.0357142857142857 0.81578256302521 0.714749824747951 0.913397049977102 GO:0046966 nuclear thyroid hormone receptor binding 1/816 28/18639 0.0357142857142857 0.81578256302521 0.714749824747951 0.913397049977102 GO:0051019 mitogen-activated protein kinase binding 1/816 28/18639 0.0357142857142857 0.81578256302521 0.714749824747951 0.913397049977102 GO:0051959 dynein light intermediate chain binding 1/816 28/18639 0.0357142857142857 0.81578256302521 0.714749824747951 0.913397049977102 GO:0008234 cysteine-type peptidase activity 7/816 187/18639 0.0374331550802139 0.855044825416798 0.715873243904261 0.913617778741029 GO:0008083 growth factor activity 6/816 162/18639 0.037037037037037 0.845996732026144 0.717870341751859 0.914951456795142 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/816 57/18639 0.0350877192982456 0.801470588235294 0.719090617302328 0.915292825466936 GO:0140597 protein carrier chaperone 7/816 188/18639 0.0372340425531915 0.850496714643304 0.721000689243017 0.916510135400185 GO:0106222 lncRNA binding 1/816 29/18639 0.0344827586206897 0.787652129817444 0.727256629487389 0.922676637187162 GO:0017116 single-stranded DNA helicase activity 2/816 58/18639 0.0344827586206897 0.787652129817444 0.72800573951492 0.922676637187162 GO:0140713 histone chaperone activity 6/816 164/18639 0.0365853658536585 0.835679698708752 0.728732120317436 0.922676637187162 GO:0015459 potassium channel regulator activity 2/816 59/18639 0.0338983050847458 0.774302093718844 0.736679860153496 0.927397261849994 GO:0004713 protein tyrosine kinase activity 5/816 140/18639 0.0357142857142857 0.81578256302521 0.738970806712874 0.927397261849994 GO:0015215 nucleotide transmembrane transporter activity 1/816 30/18639 0.0333333333333333 0.761397058823529 0.739215715480849 0.927397261849994 GO:0016769 transferase activity, transferring nitrogenous groups 1/816 30/18639 0.0333333333333333 0.761397058823529 0.739215715480849 0.927397261849994 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/816 30/18639 0.0333333333333333 0.761397058823529 0.739215715480849 0.927397261849994 GO:0048019 receptor antagonist activity 1/816 30/18639 0.0333333333333333 0.761397058823529 0.739215715480849 0.927397261849994 GO:0070566 adenylyltransferase activity 1/816 30/18639 0.0333333333333333 0.761397058823529 0.739215715480849 0.927397261849994 GO:0004197 cysteine-type endopeptidase activity 3/816 88/18639 0.0340909090909091 0.778701537433155 0.746684957441909 0.929607797146865 GO:0101005 deubiquitinase activity 4/816 115/18639 0.0347826086956522 0.794501278772379 0.746955000885553 0.929607797146865 GO:0005164 tumor necrosis factor receptor binding 1/816 31/18639 0.032258064516129 0.736835863377609 0.750651041192474 0.929607797146865 GO:0005184 neuropeptide hormone activity 1/816 31/18639 0.032258064516129 0.736835863377609 0.750651041192474 0.929607797146865 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/816 31/18639 0.032258064516129 0.736835863377609 0.750651041192474 0.929607797146865 GO:0005452 solute:inorganic anion antiporter activity 1/816 31/18639 0.032258064516129 0.736835863377609 0.750651041192474 0.929607797146865 GO:0008327 methyl-CpG binding 1/816 31/18639 0.032258064516129 0.736835863377609 0.750651041192474 0.929607797146865 GO:0016878 acid-thiol ligase activity 1/816 31/18639 0.032258064516129 0.736835863377609 0.750651041192474 0.929607797146865 GO:0017147 Wnt-protein binding 1/816 31/18639 0.032258064516129 0.736835863377609 0.750651041192474 0.929607797146865 GO:0047499 calcium-independent phospholipase A2 activity 1/816 31/18639 0.032258064516129 0.736835863377609 0.750651041192474 0.929607797146865 GO:0047498 calcium-dependent phospholipase A2 activity 1/816 32/18639 0.03125 0.713809742647059 0.761585518319889 0.940724528413127 GO:0160041 neuropeptide activity 1/816 32/18639 0.03125 0.713809742647059 0.761585518319889 0.940724528413127 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 3/816 91/18639 0.032967032967033 0.753030058177117 0.766772559113613 0.945915827096511 GO:0071889 14-3-3 protein binding 1/816 33/18639 0.0303030303030303 0.692179144385027 0.77204105747456 0.95015328215461 GO:0043178 alcohol binding 3/816 92/18639 0.0326086956521739 0.744844948849105 0.773173638548288 0.95015328215461 GO:0052689 carboxylic ester hydrolase activity 3/816 92/18639 0.0326086956521739 0.744844948849105 0.773173638548288 0.95015328215461 GO:0004536 DNA nuclease activity 2/816 64/18639 0.03125 0.713809742647059 0.776578531634701 0.953118734228541 GO:0008376 acetylgalactosaminyltransferase activity 1/816 34/18639 0.0294117647058824 0.671820934256055 0.782038611871032 0.956156623419926 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/816 34/18639 0.0294117647058824 0.671820934256055 0.782038611871032 0.956156623419926 GO:0030332 cyclin binding 1/816 34/18639 0.0294117647058824 0.671820934256055 0.782038611871032 0.956156623419926 GO:0120013 lipid transfer activity 2/816 65/18639 0.0307692307692308 0.702828054298643 0.783893712349405 0.957102261872392 GO:0008528 G protein-coupled peptide receptor activity 4/816 122/18639 0.0327868852459016 0.748915139826422 0.786906653798885 0.957102261872392 GO:0008235 metalloexopeptidase activity 2/816 66/18639 0.0303030303030303 0.692179144385027 0.790997598003625 0.957102261872392 GO:0008276 protein methyltransferase activity 3/816 95/18639 0.0315789473684211 0.721323529411765 0.79151662649697 0.957102261872392 GO:0004623 phospholipase A2 activity 1/816 35/18639 0.0285714285714286 0.652626050420168 0.791598219111733 0.957102261872392 GO:0034061 DNA polymerase activity 1/816 35/18639 0.0285714285714286 0.652626050420168 0.791598219111733 0.957102261872392 GO:0000510 H3-H4 histone complex chaperone activity 5/816 151/18639 0.033112582781457 0.756354694195559 0.795801791231585 0.957102261872392 GO:0140584 chromatin extrusion motor activity 5/816 151/18639 0.033112582781457 0.756354694195559 0.795801791231585 0.957102261872392 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 5/816 151/18639 0.033112582781457 0.756354694195559 0.795801791231585 0.957102261872392 GO:0140849 ATP-dependent H2AZ histone chaperone activity 5/816 151/18639 0.033112582781457 0.756354694195559 0.795801791231585 0.957102261872392 GO:0016500 protein-hormone receptor activity 2/816 67/18639 0.0298507462686567 0.68184811237928 0.797894641894465 0.957102261872392 GO:0042054 histone methyltransferase activity 2/816 67/18639 0.0298507462686567 0.68184811237928 0.797894641894465 0.957102261872392 GO:0050840 extracellular matrix binding 2/816 67/18639 0.0298507462686567 0.68184811237928 0.797894641894465 0.957102261872392 GO:0031267 small GTPase binding 10/816 283/18639 0.0353356890459364 0.807134691332363 0.797990117077601 0.957102261872392 GO:0015616 DNA translocase activity 5/816 152/18639 0.0328947368421053 0.751378676470588 0.800449994580092 0.957102261872392 GO:0140674 ATP-dependent histone chaperone activity 5/816 152/18639 0.0328947368421053 0.751378676470588 0.800449994580092 0.957102261872392 GO:0016409 palmitoyltransferase activity 1/816 36/18639 0.0277777777777778 0.634497549019608 0.800739041150264 0.957102261872392 GO:0045505 dynein intermediate chain binding 1/816 36/18639 0.0277777777777778 0.634497549019608 0.800739041150264 0.957102261872392 GO:0003777 microtubule motor activity 2/816 68/18639 0.0294117647058824 0.671820934256055 0.804589312808898 0.958635491627634 GO:0140223 general transcription initiation factor activity 2/816 68/18639 0.0294117647058824 0.671820934256055 0.804589312808898 0.958635491627634 GO:0061775 cohesin loader activity 5/816 153/18639 0.0326797385620915 0.74646770472895 0.805014403479189 0.958635491627634 GO:0042578 phosphoric ester hydrolase activity 13/816 363/18639 0.0358126721763085 0.818029897909577 0.808118307503976 0.960534974383514 GO:0008170 N-methyltransferase activity 3/816 98/18639 0.0306122448979592 0.699242196878751 0.808608526822334 0.960534974383514 GO:0001653 peptide receptor activity 4/816 128/18639 0.03125 0.713809742647059 0.816999619711064 0.969101344764557 GO:0000146 microfilament motor activity 1/816 38/18639 0.0263157894736842 0.601102941176471 0.817836826851255 0.969101344764557 GO:0140299 molecular sensor activity 2/816 71/18639 0.028169014084507 0.643434134217067 0.823503806244356 0.974614726355697 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/816 39/18639 0.0256410256410256 0.585690045248869 0.825828071907401 0.975428792907793 GO:0016798 hydrolase activity, acting on glycosyl bonds 4/816 130/18639 0.0307692307692308 0.702828054298643 0.826221683066538 0.975428792907793 GO:0005518 collagen binding 2/816 72/18639 0.0277777777777778 0.634497549019608 0.829433654301132 0.976951344979886 GO:0008238 exopeptidase activity 3/816 102/18639 0.0294117647058824 0.671820934256055 0.829544534342963 0.976951344979886 GO:0003689 DNA clamp loader activity 5/816 160/18639 0.03125 0.713809742647059 0.834681657282405 0.981187329882634 GO:0004521 RNA endonuclease activity 2/816 73/18639 0.0273972602739726 0.625805801772764 0.83518338797502 0.981187329882634 GO:0035064 methylated histone binding 2/816 74/18639 0.027027027027027 0.617348966613673 0.840757388888472 0.982950344491208 GO:0001727 lipid kinase activity 1/816 41/18639 0.024390243902439 0.557119799139168 0.840775424736496 0.982950344491208 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/816 41/18639 0.024390243902439 0.557119799139168 0.840775424736496 0.982950344491208 GO:0140828 metal cation:monoatomic cation antiporter activity 1/816 41/18639 0.024390243902439 0.557119799139168 0.840775424736496 0.982950344491208 GO:0019003 GDP binding 2/816 75/18639 0.0266666666666667 0.609117647058824 0.846160000723148 0.986318175739201 GO:0015297 antiporter activity 4/816 135/18639 0.0296296296296296 0.676797385620915 0.847600141707723 0.986318175739201 GO:0004402 histone acetyltransferase activity 1/816 42/18639 0.0238095238095238 0.543855042016807 0.847761512133798 0.986318175739201 GO:0004520 DNA endonuclease activity 1/816 42/18639 0.0238095238095238 0.543855042016807 0.847761512133798 0.986318175739201 GO:0015081 sodium ion transmembrane transporter activity 5/816 164/18639 0.0304878048780488 0.69639974892396 0.849912051834549 0.987624524562276 GO:0140034 methylation-dependent protein binding 2/816 76/18639 0.0263157894736842 0.601102941176471 0.851395524146072 0.988153500850694 GO:0008375 acetylglucosaminyltransferase activity 1/816 43/18639 0.0232558139534884 0.531207250341997 0.854441439331669 0.990492428465301 GO:0003724 RNA helicase activity 2/816 77/18639 0.025974025974026 0.59329640947288 0.856468212251618 0.991645725269644 GO:0016790 thiolester hydrolase activity 1/816 44/18639 0.0227272727272727 0.51913435828877 0.860828607835937 0.993104792473392 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/816 44/18639 0.0227272727272727 0.51913435828877 0.860828607835937 0.993104792473392 GO:0043014 alpha-tubulin binding 1/816 44/18639 0.0227272727272727 0.51913435828877 0.860828607835937 0.993104792473392 GO:0008186 ATP-dependent activity, acting on RNA 2/816 79/18639 0.0253164556962025 0.578276247207744 0.866141833007069 0.9943241350132 GO:0042605 peptide antigen binding 1/816 45/18639 0.0222222222222222 0.507598039215686 0.86693583321942 0.9943241350132 GO:0051539 4 iron, 4 sulfur cluster binding 1/816 45/18639 0.0222222222222222 0.507598039215686 0.86693583321942 0.9943241350132 GO:0106310 protein serine kinase activity 12/816 361/18639 0.0332409972299169 0.759287925696594 0.871057003643468 0.9943241350132 GO:0043495 protein-membrane adaptor activity 1/816 47/18639 0.0212765957446809 0.485998122653317 0.878358939660361 0.9943241350132 GO:0061733 protein-lysine-acetyltransferase activity 1/816 47/18639 0.0212765957446809 0.485998122653317 0.878358939660361 0.9943241350132 GO:0140938 histone H3 methyltransferase activity 1/816 47/18639 0.0212765957446809 0.485998122653317 0.878358939660361 0.9943241350132 GO:0019955 cytokine binding 4/816 144/18639 0.0277777777777778 0.634497549019608 0.880489611768537 0.9943241350132 GO:0005085 guanyl-nucleotide exchange factor activity 7/816 230/18639 0.0304347826086957 0.695188618925831 0.881211908237771 0.9943241350132 GO:0008188 neuropeptide receptor activity 1/816 48/18639 0.0208333333333333 0.475873161764706 0.883697746955818 0.9943241350132 GO:0030165 PDZ domain binding 2/816 83/18639 0.0240963855421687 0.550407512402551 0.88371604107522 0.9943241350132 GO:0008194 UDP-glycosyltransferase activity 4/816 145/18639 0.0275862068965517 0.630121703853955 0.88373422308915 0.9943241350132 GO:0005004 GPI-linked ephrin receptor activity 1/816 49/18639 0.0204081632653061 0.466161464585834 0.888802509393775 0.9943241350132 GO:0005008 hepatocyte growth factor receptor activity 1/816 49/18639 0.0204081632653061 0.466161464585834 0.888802509393775 0.9943241350132 GO:0005009 insulin receptor activity 1/816 49/18639 0.0204081632653061 0.466161464585834 0.888802509393775 0.9943241350132 GO:0005011 macrophage colony-stimulating factor receptor activity 1/816 49/18639 0.0204081632653061 0.466161464585834 0.888802509393775 0.9943241350132 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/816 49/18639 0.0204081632653061 0.466161464585834 0.888802509393775 0.9943241350132 GO:0005020 stem cell factor receptor activity 1/816 49/18639 0.0204081632653061 0.466161464585834 0.888802509393775 0.9943241350132 GO:0008288 boss receptor activity 1/816 49/18639 0.0204081632653061 0.466161464585834 0.888802509393775 0.9943241350132 GO:0035254 glutamate receptor binding 1/816 49/18639 0.0204081632653061 0.466161464585834 0.888802509393775 0.9943241350132 GO:0036332 placental growth factor receptor activity 1/816 49/18639 0.0204081632653061 0.466161464585834 0.888802509393775 0.9943241350132 GO:0038062 protein tyrosine kinase collagen receptor activity 1/816 49/18639 0.0204081632653061 0.466161464585834 0.888802509393775 0.9943241350132 GO:0060175 brain-derived neurotrophic factor receptor activity 1/816 49/18639 0.0204081632653061 0.466161464585834 0.888802509393775 0.9943241350132 GO:0005125 cytokine activity 7/816 234/18639 0.0299145299145299 0.683305052790347 0.89138713381394 0.9943241350132 GO:0005006 epidermal growth factor receptor activity 1/816 50/18639 0.02 0.456838235294118 0.893683475092252 0.9943241350132 GO:0005007 fibroblast growth factor receptor activity 1/816 50/18639 0.02 0.456838235294118 0.893683475092252 0.9943241350132 GO:0005017 platelet-derived growth factor receptor activity 1/816 50/18639 0.02 0.456838235294118 0.893683475092252 0.9943241350132 GO:0005019 platelet-derived growth factor beta-receptor activity 1/816 50/18639 0.02 0.456838235294118 0.893683475092252 0.9943241350132 GO:0015605 organophosphate ester transmembrane transporter activity 1/816 50/18639 0.02 0.456838235294118 0.893683475092252 0.9943241350132 GO:0032813 tumor necrosis factor receptor superfamily binding 1/816 50/18639 0.02 0.456838235294118 0.893683475092252 0.9943241350132 GO:0050660 flavin adenine dinucleotide binding 2/816 86/18639 0.0232558139534884 0.531207250341997 0.895468496461898 0.9943241350132 GO:0005010 insulin-like growth factor receptor activity 1/816 51/18639 0.0196078431372549 0.44788062283737 0.898350443962267 0.9943241350132 GO:0005021 vascular endothelial growth factor receptor activity 1/816 51/18639 0.0196078431372549 0.44788062283737 0.898350443962267 0.9943241350132 GO:0005030 neurotrophin receptor activity 1/816 51/18639 0.0196078431372549 0.44788062283737 0.898350443962267 0.9943241350132 GO:0016597 amino acid binding 1/816 51/18639 0.0196078431372549 0.44788062283737 0.898350443962267 0.9943241350132 GO:0008081 phosphoric diester hydrolase activity 2/816 87/18639 0.0229885057471264 0.525101419878296 0.899133895240864 0.9943241350132 GO:0005003 ephrin receptor activity 1/816 53/18639 0.0188679245283019 0.430979467258602 0.907079466448789 0.997951735912723 GO:0005005 transmembrane-ephrin receptor activity 1/816 53/18639 0.0188679245283019 0.430979467258602 0.907079466448789 0.997951735912723 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/816 53/18639 0.0188679245283019 0.430979467258602 0.907079466448789 0.997951735912723 GO:0038064 collagen receptor activity 1/816 53/18639 0.0188679245283019 0.430979467258602 0.907079466448789 0.997951735912723 GO:0004674 protein serine/threonine kinase activity 14/816 433/18639 0.0323325635103926 0.738537562831137 0.907606469498147 0.997951735912723 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/816 54/18639 0.0185185185185185 0.422998366013072 0.911159050833691 0.999822340796336 GO:0030695 GTPase regulator activity 16/816 489/18639 0.032719836400818 0.747383616023096 0.911991223738865 0.999822340796336 GO:0016741 transferase activity, transferring one-carbon groups 6/816 215/18639 0.027906976744186 0.637448700410397 0.913307605043532 0.999822340796336 GO:0060589 nucleoside-triphosphatase regulator activity 16/816 490/18639 0.0326530612244898 0.745858343337335 0.913469318646393 0.999822340796336 GO:0008374 O-acyltransferase activity 1/816 55/18639 0.0181818181818182 0.415307486631016 0.915059734961736 0.99999979689354 GO:0051213 dioxygenase activity 2/816 93/18639 0.021505376344086 0.491223908918406 0.918723666278175 0.99999979689354 GO:0004519 endonuclease activity 3/816 127/18639 0.0236220472440945 0.53957271885132 0.92061979432744 0.99999979689354 GO:0008408 3'-5' exonuclease activity 1/816 58/18639 0.0172413793103448 0.393826064908722 0.925765046981628 0.99999979689354 GO:0004896 cytokine receptor activity 2/816 96/18639 0.0208333333333333 0.475873161764706 0.927120318344472 0.99999979689354 GO:0031593 polyubiquitin modification-dependent protein binding 1/816 59/18639 0.0169491525423729 0.387151046859422 0.929025136409699 0.99999979689354 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/816 60/18639 0.0166666666666667 0.380698529411765 0.932142224067917 0.99999979689354 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/816 60/18639 0.0166666666666667 0.380698529411765 0.932142224067917 0.99999979689354 GO:0015026 coreceptor activity 1/816 61/18639 0.0163934426229508 0.374457569913211 0.935122575279531 0.99999979689354 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 4/816 167/18639 0.0239520958083832 0.547111659034871 0.938007727178438 0.99999979689354 GO:0016874 ligase activity 4/816 167/18639 0.0239520958083832 0.547111659034871 0.938007727178438 0.99999979689354 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 15/816 484/18639 0.0309917355371901 0.707910488575596 0.940178784920581 0.99999979689354 GO:0140767 enzyme-substrate adaptor activity 3/816 139/18639 0.0215827338129496 0.49299090139653 0.946117159399366 0.99999979689354 GO:0001216 DNA-binding transcription activator activity 15/816 491/18639 0.0305498981670061 0.697818078351504 0.947489396488381 0.99999979689354 GO:0140030 modification-dependent protein binding 4/816 173/18639 0.023121387283237 0.528136688201292 0.94814535342292 0.99999979689354 GO:0008013 beta-catenin binding 2/816 106/18639 0.0188679245283019 0.430979467258602 0.949566298420191 0.99999979689354 GO:0008173 RNA methyltransferase activity 1/816 67/18639 0.0149253731343284 0.34092405618964 0.950450995542117 0.99999979689354 GO:0005516 calmodulin binding 5/816 207/18639 0.0241545893719807 0.551736999147485 0.951590367176792 0.99999979689354 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 7/816 268/18639 0.0261194029850746 0.59661709833187 0.951698127334581 0.99999979689354 GO:0004843 cysteine-type deubiquitinase activity 2/816 108/18639 0.0185185185185185 0.422998366013072 0.953183613680427 0.99999979689354 GO:0002039 p53 binding 1/816 69/18639 0.0144927536231884 0.331042199488491 0.954709534854052 0.99999979689354 GO:0016279 protein-lysine N-methyltransferase activity 1/816 69/18639 0.0144927536231884 0.331042199488491 0.954709534854052 0.99999979689354 GO:0035173 histone kinase activity 10/816 360/18639 0.0277777777777778 0.634497549019608 0.956297050775598 0.99999979689354 GO:0016278 lysine N-methyltransferase activity 1/816 70/18639 0.0142857142857143 0.326313025210084 0.956699681303115 0.99999979689354 GO:0035402 histone H3T11 kinase activity 6/816 247/18639 0.0242914979757085 0.554864253393665 0.962134497317876 0.99999979689354 GO:0001217 DNA-binding transcription repressor activity 7/816 278/18639 0.0251798561151079 0.575156051629285 0.962516710711161 0.99999979689354 GO:0140375 immune receptor activity 3/816 156/18639 0.0192307692307692 0.439267533936652 0.969444868625877 0.99999979689354 GO:0019199 transmembrane receptor protein kinase activity 1/816 78/18639 0.0128205128205128 0.292845022624434 0.969777744072355 0.99999979689354 GO:0004540 RNA nuclease activity 2/816 121/18639 0.0165289256198347 0.377552260573651 0.971304448280259 0.99999979689354 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/816 122/18639 0.0163934426229508 0.374457569913211 0.97237536369605 0.99999979689354 GO:0141003 histone H2AX kinase activity 9/816 354/18639 0.0254237288135593 0.580726570289133 0.974703601932386 0.99999979689354 GO:0140996 histone H3 kinase activity 9/816 357/18639 0.0252100840336134 0.575846515076619 0.976499629569154 0.99999979689354 GO:0004527 exonuclease activity 1/816 84/18639 0.0119047619047619 0.271927521008403 0.976924106076208 0.99999979689354 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/816 86/18639 0.0116279069767442 0.265603625170999 0.978909163389689 0.99999979689354 GO:0005201 extracellular matrix structural constituent 3/816 168/18639 0.0178571428571429 0.407891281512605 0.979755254192035 0.99999979689354 GO:0008168 methyltransferase activity 4/816 204/18639 0.0196078431372549 0.44788062283737 0.980203001763235 0.99999979689354 GO:0005096 GTPase activator activity 6/816 271/18639 0.022140221402214 0.505724983720425 0.980545252181016 0.99999979689354 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 5/816 243/18639 0.0205761316872428 0.469998184458969 0.983102439111149 0.99999979689354 GO:0004518 nuclease activity 4/816 209/18639 0.0191387559808612 0.437165775401069 0.983145768579434 0.99999979689354 GO:0004676 3-phosphoinositide-dependent protein kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:0004711 ribosomal protein S6 kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:0035175 histone H3S10 kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:0035979 histone H2AXS139 kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:0044022 histone H3S28 kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:0044023 histone H4S1 kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:0044024 histone H2AS1 kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:0044025 histone H2BS14 kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:0072354 histone H3T3 kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:0072371 histone H2AS121 kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:0072518 Rho-dependent protein serine/threonine kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:0140823 histone H2BS36 kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:0140855 histone H3S57 kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:0140995 histone H2A kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:0140997 histone H4 kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:0140998 histone H2B kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:1990244 histone H2AT120 kinase activity 5/816 245/18639 0.0204081632653061 0.466161464585834 0.984098713544779 0.99999979689354 GO:0004677 DNA-dependent protein kinase activity 5/816 246/18639 0.0203252032520325 0.46426649928264 0.984575878763798 0.99999979689354 GO:0140857 histone H3T45 kinase activity 5/816 246/18639 0.0203252032520325 0.46426649928264 0.984575878763798 0.99999979689354 GO:0035403 histone H3T6 kinase activity 5/816 247/18639 0.0202429149797571 0.462386877828054 0.985039543669705 0.99999979689354 GO:0004679 AMP-activated protein kinase activity 5/816 248/18639 0.0201612903225806 0.460522414611006 0.985490058945527 0.99999979689354 GO:0030527 structural constituent of chromatin 1/816 98/18639 0.0102040816326531 0.233080732292917 0.98770821491167 0.99999979689354 GO:0005543 phospholipid binding 12/816 497/18639 0.0241448692152917 0.551514972186057 0.992966903544608 0.99999979689354 GO:1902936 phosphatidylinositol bisphosphate binding 1/816 111/18639 0.00900900900900901 0.205782988871224 0.993154250890105 0.99999979689354 GO:0140098 catalytic activity, acting on RNA 8/816 387/18639 0.020671834625323 0.47218422252622 0.995422818231775 0.99999979689354 GO:0045182 translation regulator activity 7/816 356/18639 0.0196629213483146 0.449138714474554 0.995716533891268 0.99999979689354 GO:0003823 antigen binding 2/816 174/18639 0.0114942528735632 0.262550709939148 0.996391317657734 0.99999979689354 GO:0016755 aminoacyltransferase activity 11/816 496/18639 0.0221774193548387 0.506574656072106 0.996733940185847 0.99999979689354 GO:0005262 calcium channel activity 1/816 131/18639 0.00763358778625954 0.174365738661877 0.997220306686237 0.99999979689354 GO:1901981 phosphatidylinositol phosphate binding 2/816 185/18639 0.0108108108108108 0.246939586645469 0.997680641552144 0.99999979689354 GO:0019787 ubiquitin-like protein transferase activity 10/816 479/18639 0.0208768267223382 0.476866633918703 0.997830479493792 0.99999979689354 GO:0140101 catalytic activity, acting on a tRNA 1/816 139/18639 0.00719424460431655 0.16433030046551 0.998062212771335 0.99999979689354 GO:0015085 calcium ion transmembrane transporter activity 1/816 147/18639 0.00680272108843537 0.155387154861945 0.998649340203287 0.99999979689354 GO:0035091 phosphatidylinositol binding 4/816 284/18639 0.0140845070422535 0.321717067108534 0.998692569081822 0.99999979689354 GO:0061659 ubiquitin-like protein ligase activity 6/816 372/18639 0.0161290322580645 0.368417931688805 0.999136525688405 0.99999979689354 GO:0004842 ubiquitin-protein transferase activity 8/816 449/18639 0.0178173719376392 0.406982837678501 0.999273522206396 0.99999979689354 GO:0061630 ubiquitin protein ligase activity 5/816 353/18639 0.0141643059490085 0.323539826695551 0.999542590294367 0.99999979689354 GO:0005244 voltage-gated monoatomic ion channel activity 1/816 173/18639 0.00578034682080925 0.132034172050323 0.999582558050714 0.99999979689354 GO:0022832 voltage-gated channel activity 1/816 175/18639 0.00571428571428571 0.130525210084034 0.999618636820827 0.99999979689354 GO:0005216 monoatomic ion channel activity 7/816 448/18639 0.015625 0.356904871323529 0.999761310033092 0.99999979689354 GO:0046873 metal ion transmembrane transporter activity 7/816 450/18639 0.0155555555555556 0.35531862745098 0.999776516726586 0.99999979689354 GO:0030371 translation repressor activity 2/816 329/18639 0.0060790273556231 0.138856606472376 0.999994261778913 0.99999979689354 GO:0022836 gated channel activity 1/816 318/18639 0.00314465408805031 0.0718299112097669 0.999999420429984 0.99999979689354 GO:0005261 monoatomic cation channel activity 1/816 341/18639 0.00293255131964809 0.0669850784888736 0.99999979689354 0.99999979689354