ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 76/789 175/18639 0.434285714285714 10.2593807713199 1.62509571217638e-57 1.42683403529086e-54 GO:0048027 mRNA 5'-UTR binding 13/789 24/18639 0.541666666666667 12.796102661597 2.06111224525595e-12 9.04828275667363e-10 GO:0031720 haptoglobin binding 8/789 10/18639 0.8 18.8988593155894 4.15587737363102e-10 1.21628677801601e-07 GO:0019843 rRNA binding 17/789 65/18639 0.261538461538462 6.17847323778883 1.05034550356314e-09 2.30550838032109e-07 GO:0005344 oxygen carrier activity 8/789 14/18639 0.571428571428571 13.499185225421 2.38309944619664e-08 4.18472262752129e-06 GO:0045296 cadherin binding 38/789 334/18639 0.11377245508982 2.68771202841465 3.13337157254697e-08 4.58516706782707e-06 GO:1990948 ubiquitin ligase inhibitor activity 7/789 11/18639 0.636363636363636 15.0331835464915 6.74606999348888e-08 8.46149922040463e-06 GO:0055105 ubiquitin-protein transferase inhibitor activity 7/789 15/18639 0.466666666666667 11.0243346007605 1.13316794572016e-06 0.000124365182042787 GO:0001216 DNA-binding transcription activator activity 44/789 491/18639 0.0896130346232179 2.11698016773404 2.41590783508069e-06 0.000235685231022317 GO:0004601 peroxidase activity 12/789 57/18639 0.210526315789474 4.97338403041825 3.72108315381681e-06 0.000312849780904335 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 43/789 484/18639 0.0888429752066116 2.09878861201018 3.91953028467845e-06 0.000312849780904335 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 12/789 59/18639 0.203389830508475 4.80479474125153 5.44921309997414e-06 0.000398700758481441 GO:0098632 cell-cell adhesion mediator activity 11/789 55/18639 0.2 4.72471482889734 1.58547187647035e-05 0.00107080331349305 GO:0140517 protein-RNA adaptor activity 7/789 22/18639 0.318181818181818 7.51659177324577 2.31512497750889e-05 0.00145191409303772 GO:0017147 Wnt-protein binding 8/789 31/18639 0.258064516129032 6.09640623083528 3.29663666162866e-05 0.00192963132593998 GO:0016209 antioxidant activity 13/789 86/18639 0.151162790697674 3.57100539393403 6.34492752635451e-05 0.00335602622810374 GO:0019825 oxygen binding 8/789 34/18639 0.235294117647059 5.55848803399687 6.77932727281943e-05 0.00335602622810374 GO:0003779 actin binding 37/789 443/18639 0.0835214446952596 1.97307504141311 6.88023600294616e-05 0.00335602622810374 GO:0098631 cell adhesion mediator activity 12/789 76/18639 0.157894736842105 3.73003802281369 7.81201819280634e-05 0.00360997472278103 GO:1990247 N6-methyladenosine-containing RNA reader activity 5/789 12/18639 0.416666666666667 9.84315589353612 8.28984415193352e-05 0.00363924158269882 GO:0008301 DNA binding, bending 6/789 19/18639 0.315789473684211 7.46007604562738 9.53507376092467e-05 0.00398656893432946 GO:0008266 poly(U) RNA binding 7/789 27/18639 0.259259259259259 6.12463033375581 0.000100173077637383 0.00399781646207373 GO:0070742 C2H2 zinc finger domain binding 5/789 14/18639 0.357142857142857 8.4369907658881 0.000195220572277232 0.00745233315040911 GO:0008187 poly-pyrimidine tract binding 7/789 30/18639 0.233333333333333 5.51216730038023 0.000205558895218641 0.00752002958341527 GO:0031386 protein tag activity 5/789 15/18639 0.333333333333333 7.8745247148289 0.000282658413312496 0.00954515718801428 GO:0141047 molecular tag activity 5/789 15/18639 0.333333333333333 7.8745247148289 0.000282658413312496 0.00954515718801428 GO:0055106 ubiquitin-protein transferase regulator activity 7/789 36/18639 0.194444444444444 4.59347275031686 0.000675798169184658 0.0217447191964217 GO:0097110 scaffold protein binding 10/789 70/18639 0.142857142857143 3.37479630635524 0.000693453459566978 0.0217447191964217 GO:0098641 cadherin binding involved in cell-cell adhesion 5/789 18/18639 0.277777777777778 6.56210392902408 0.00072547500404102 0.0219643811568281 GO:0036002 pre-mRNA binding 9/789 59/18639 0.152542372881356 3.60359605593865 0.000783546564986786 0.0229317961352799 GO:0045294 alpha-catenin binding 4/789 11/18639 0.363636363636364 8.59039059799516 0.000828326434484662 0.0234603422412107 GO:0140297 DNA-binding transcription factor binding 36/789 488/18639 0.0737704918032787 1.74272268279 0.000911707895796903 0.0250149853909275 GO:0015026 coreceptor activity 9/789 61/18639 0.147540983606557 3.48544536558 0.00100304287806436 0.0266870196042577 GO:0005246 calcium channel regulator activity 8/789 53/18639 0.150943396226415 3.56582251237535 0.0016290381169094 0.0396900645546179 GO:0031994 insulin-like growth factor I binding 4/789 13/18639 0.307692307692308 7.26879204445744 0.00167704931593672 0.0396900645546179 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 4/789 13/18639 0.307692307692308 7.26879204445744 0.00167704931593672 0.0396900645546179 GO:0097157 pre-mRNA intronic binding 4/789 13/18639 0.307692307692308 7.26879204445744 0.00167704931593672 0.0396900645546179 GO:0004857 enzyme inhibitor activity 31/789 416/18639 0.0745192307692308 1.76041057326704 0.00171779322673745 0.0396900645546179 GO:0019838 growth factor binding 14/789 136/18639 0.102941176470588 2.43183851487363 0.0018909698256101 0.0425710642791196 GO:0048306 calcium-dependent protein binding 10/789 80/18639 0.125 2.95294676806084 0.00197087176685629 0.0432606352824956 GO:0005201 extracellular matrix structural constituent 15/789 168/18639 0.0892857142857143 2.10924769147203 0.00522844014678874 0.111965132899525 GO:0019199 transmembrane receptor protein kinase activity 9/789 78/18639 0.115384615384615 2.72579701667154 0.00558487369745714 0.116750454913509 GO:0003746 translation elongation factor activity 4/789 18/18639 0.222222222222222 5.24968314321926 0.00606375706283359 0.123813458166695 GO:0005003 ephrin receptor activity 7/789 53/18639 0.132075471698113 3.12009469832843 0.00670790375186113 0.127822414905937 GO:0005005 transmembrane-ephrin receptor activity 7/789 53/18639 0.132075471698113 3.12009469832843 0.00670790375186113 0.127822414905937 GO:0051018 protein kinase A binding 7/789 53/18639 0.132075471698113 3.12009469832843 0.00670790375186113 0.127822414905937 GO:0003785 actin monomer binding 5/789 29/18639 0.172413793103448 4.0730300249115 0.0068424299551014 0.127822414905937 GO:0005522 profilin binding 3/789 10/18639 0.3 7.08707224334601 0.00725249143700982 0.132660155868638 GO:0005520 insulin-like growth factor binding 4/789 19/18639 0.210526315789474 4.97338403041825 0.00742728711028 0.13308485883318 GO:0051015 actin filament binding 17/789 209/18639 0.0813397129186603 1.92153473902523 0.00776220282025738 0.13630428152372 GO:0035198 miRNA binding 6/789 42/18639 0.142857142857143 3.37479630635524 0.00806177660708516 0.137997427659141 GO:0003730 mRNA 3'-UTR binding 20/789 262/18639 0.0763358778625954 1.8033262705715 0.0081729683807236 0.137997427659141 GO:0001540 amyloid-beta binding 9/789 83/18639 0.108433734939759 2.56159237711301 0.0083588023110252 0.138472234510946 GO:0001221 transcription coregulator binding 11/789 115/18639 0.0956521739130435 2.25964622251612 0.00954827715885677 0.152425224463204 GO:0017124 SH3 domain binding 11/789 115/18639 0.0956521739130435 2.25964622251612 0.00954827715885677 0.152425224463204 GO:0001223 transcription coactivator binding 6/789 44/18639 0.136363636363636 3.22139647424819 0.0101040470160019 0.155637776842976 GO:0030020 extracellular matrix structural constituent conferring tensile strength 6/789 44/18639 0.136363636363636 3.22139647424819 0.0101040470160019 0.155637776842976 GO:0016801 hydrolase activity, acting on ether bonds 3/789 12/18639 0.25 5.90589353612167 0.0124817242736199 0.182649231870637 GO:0016803 ether hydrolase activity 3/789 12/18639 0.25 5.90589353612167 0.0124817242736199 0.182649231870637 GO:0097371 MDM2/MDM4 family protein binding 3/789 12/18639 0.25 5.90589353612167 0.0124817242736199 0.182649231870637 GO:0003727 single-stranded RNA binding 9/789 89/18639 0.101123595505618 2.38890075618405 0.0129423115696052 0.184767493605427 GO:0004714 transmembrane receptor protein tyrosine kinase activity 7/789 60/18639 0.116666666666667 2.75608365019011 0.0130473628741873 0.184767493605427 GO:0019210 kinase inhibitor activity 9/789 90/18639 0.1 2.36235741444867 0.0138584174304297 0.191194415645819 GO:0008201 heparin binding 14/789 172/18639 0.0813953488372093 1.92284905827217 0.014733749625967 0.191194415645819 GO:0043274 phospholipase binding 4/789 23/18639 0.173913043478261 4.10844767730203 0.0148449363197982 0.191194415645819 GO:0005172 vascular endothelial growth factor receptor binding 3/789 13/18639 0.230769230769231 5.45159403334308 0.0157231267609248 0.191194415645819 GO:0019855 calcium channel inhibitor activity 3/789 13/18639 0.230769230769231 5.45159403334308 0.0157231267609248 0.191194415645819 GO:0005004 GPI-linked ephrin receptor activity 6/789 49/18639 0.122448979591837 2.89268254830449 0.0167676195953623 0.191194415645819 GO:0005008 hepatocyte growth factor receptor activity 6/789 49/18639 0.122448979591837 2.89268254830449 0.0167676195953623 0.191194415645819 GO:0005009 insulin receptor activity 6/789 49/18639 0.122448979591837 2.89268254830449 0.0167676195953623 0.191194415645819 GO:0005011 macrophage colony-stimulating factor receptor activity 6/789 49/18639 0.122448979591837 2.89268254830449 0.0167676195953623 0.191194415645819 GO:0005018 platelet-derived growth factor alpha-receptor activity 6/789 49/18639 0.122448979591837 2.89268254830449 0.0167676195953623 0.191194415645819 GO:0005020 stem cell factor receptor activity 6/789 49/18639 0.122448979591837 2.89268254830449 0.0167676195953623 0.191194415645819 GO:0008288 boss receptor activity 6/789 49/18639 0.122448979591837 2.89268254830449 0.0167676195953623 0.191194415645819 GO:0036332 placental growth factor receptor activity 6/789 49/18639 0.122448979591837 2.89268254830449 0.0167676195953623 0.191194415645819 GO:0038062 protein tyrosine kinase collagen receptor activity 6/789 49/18639 0.122448979591837 2.89268254830449 0.0167676195953623 0.191194415645819 GO:0060175 brain-derived neurotrophic factor receptor activity 6/789 49/18639 0.122448979591837 2.89268254830449 0.0167676195953623 0.191194415645819 GO:0042562 hormone binding 9/789 94/18639 0.0957446808510638 2.26183156702532 0.0180070601996131 0.196545132509879 GO:0005006 epidermal growth factor receptor activity 6/789 50/18639 0.12 2.8348288973384 0.0183931490624136 0.196545132509879 GO:0005007 fibroblast growth factor receptor activity 6/789 50/18639 0.12 2.8348288973384 0.0183931490624136 0.196545132509879 GO:0005017 platelet-derived growth factor receptor activity 6/789 50/18639 0.12 2.8348288973384 0.0183931490624136 0.196545132509879 GO:0005019 platelet-derived growth factor beta-receptor activity 6/789 50/18639 0.12 2.8348288973384 0.0183931490624136 0.196545132509879 GO:0099106 ion channel regulator activity 13/789 160/18639 0.08125 1.91941539923954 0.0185800068317995 0.196545132509879 GO:0042043 neurexin family protein binding 3/789 14/18639 0.214285714285714 5.06219445953286 0.0193922211102497 0.19798104807906 GO:0042813 Wnt receptor activity 3/789 14/18639 0.214285714285714 5.06219445953286 0.0193922211102497 0.19798104807906 GO:1990825 sequence-specific mRNA binding 3/789 14/18639 0.214285714285714 5.06219445953286 0.0193922211102497 0.19798104807906 GO:0005010 insulin-like growth factor receptor activity 6/789 51/18639 0.117647058823529 2.77924401699843 0.0201232150925218 0.198518908440833 GO:0005021 vascular endothelial growth factor receptor activity 6/789 51/18639 0.117647058823529 2.77924401699843 0.0201232150925218 0.198518908440833 GO:0005030 neurotrophin receptor activity 6/789 51/18639 0.117647058823529 2.77924401699843 0.0201232150925218 0.198518908440833 GO:0005109 frizzled binding 5/789 38/18639 0.131578947368421 3.10836501901141 0.0211881719465328 0.204430933725888 GO:0042162 telomeric DNA binding 5/789 38/18639 0.131578947368421 3.10836501901141 0.0211881719465328 0.204430933725888 GO:0008143 poly(A) binding 4/789 26/18639 0.153846153846154 3.63439602222872 0.0226852915028556 0.215652253715084 GO:0050840 extracellular matrix binding 7/789 67/18639 0.104477611940299 2.46813461211055 0.022842436896928 0.215652253715084 GO:0038064 collagen receptor activity 6/789 53/18639 0.113207547169811 2.67436688428151 0.0239076773002094 0.222626626176587 GO:0008135 translation factor activity, RNA binding 8/789 83/18639 0.0963855421686747 2.27697100187824 0.0240883023767378 0.222626626176587 GO:0004860 protein kinase inhibitor activity 8/789 84/18639 0.0952380952380952 2.24986420423683 0.0256743512283962 0.232392581221978 GO:0180051 translation factor activity 8/789 84/18639 0.0952380952380952 2.24986420423683 0.0256743512283962 0.232392581221978 GO:0016247 channel regulator activity 13/789 168/18639 0.0773809523809524 1.82801466594242 0.0265178337761433 0.237578143422998 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 3/789 16/18639 0.1875 4.42942015209125 0.0280232560419303 0.248529482876917 GO:0141108 transporter regulator activity 13/789 170/18639 0.0764705882352941 1.80650861104898 0.0288417665419265 0.25031576663122 GO:0046875 ephrin receptor binding 4/789 28/18639 0.142857142857143 3.37479630635524 0.0290799637772033 0.25031576663122 GO:0097718 disordered domain specific binding 4/789 28/18639 0.142857142857143 3.37479630635524 0.0290799637772033 0.25031576663122 GO:0019212 phosphatase inhibitor activity 6/789 56/18639 0.107142857142857 2.53109722976643 0.0304315563952431 0.25940685936916 GO:0031492 nucleosomal DNA binding 5/789 42/18639 0.119047619047619 2.81233025529603 0.0313082108806179 0.264313549549832 GO:0033218 amide binding 17/789 247/18639 0.0688259109311741 1.62591400994443 0.0340575107507014 0.28434527427276 GO:0008528 G protein-coupled peptide receptor activity 10/789 122/18639 0.0819672131147541 1.93635853643334 0.0343287005386248 0.28434527427276 GO:0061980 regulatory RNA binding 6/789 58/18639 0.103448275862069 2.4438180149469 0.0353702284648647 0.2902342111416 GO:0020037 heme binding 11/789 142/18639 0.0774647887323944 1.82999518020672 0.0389246540519045 0.316443020903446 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 22/789 349/18639 0.0630372492836676 1.48916513231721 0.0415029049968132 0.334307803552312 GO:0030291 protein serine/threonine kinase inhibitor activity 5/789 46/18639 0.108695652173913 2.56777979831377 0.0440193017790136 0.350998235877083 GO:0043425 bHLH transcription factor binding 4/789 32/18639 0.125 2.95294676806084 0.0447742624353454 0.350998235877083 GO:0070717 poly-purine tract binding 4/789 32/18639 0.125 2.95294676806084 0.0447742624353454 0.350998235877083 GO:0001653 peptide receptor activity 10/789 128/18639 0.078125 1.84559173003802 0.0452911202979988 0.351907996651707 GO:0003712 transcription coregulator activity 29/789 495/18639 0.0585858585858586 1.38400737412144 0.0489443043573852 0.376457016942631 GO:0140416 transcription regulator inhibitor activity 4/789 33/18639 0.121212121212121 2.86346353266505 0.0493081514218709 0.376457016942631 GO:0035401 histone H3Y41 kinase activity 9/789 115/18639 0.0782608695652174 1.84880145478592 0.0551981369802222 0.408951782270714 GO:0140801 histone H2AXY142 kinase activity 9/789 115/18639 0.0782608695652174 1.84880145478592 0.0551981369802222 0.408951782270714 GO:0001618 virus receptor activity 7/789 81/18639 0.0864197530864197 2.04154344458527 0.0554782170852783 0.408951782270714 GO:0031625 ubiquitin protein ligase binding 19/789 302/18639 0.0629139072847682 1.48625135346108 0.0560260471259763 0.408951782270714 GO:0044389 ubiquitin-like protein ligase binding 20/789 322/18639 0.062111801242236 1.46730274189358 0.0566871247162058 0.408951782270714 GO:0008373 sialyltransferase activity 3/789 21/18639 0.142857142857143 3.37479630635524 0.0569867907061817 0.408951782270714 GO:0046906 tetrapyrrole binding 11/789 152/18639 0.0723684210526316 1.70960076045627 0.058344331915045 0.408951782270714 GO:0140272 exogenous protein binding 7/789 82/18639 0.0853658536585366 2.01664657330984 0.0585494447879838 0.408951782270714 GO:0044325 transmembrane transporter binding 10/789 136/18639 0.0735294117647059 1.73702751062402 0.0632770062718837 0.408951782270714 GO:0016500 protein-hormone receptor activity 6/789 67/18639 0.0895522388059701 2.11554395323761 0.0637608125441202 0.408951782270714 GO:0005243 gap junction channel activity 3/789 22/18639 0.136363636363636 3.22139647424819 0.0639827711875699 0.408951782270714 GO:0070034 telomerase RNA binding 3/789 22/18639 0.136363636363636 3.22139647424819 0.0639827711875699 0.408951782270714 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.408951782270714 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.408951782270714 GO:0015187 glycine transmembrane transporter activity 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.408951782270714 GO:0015279 store-operated calcium channel activity 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.408951782270714 GO:0019911 structural constituent of myelin sheath 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.408951782270714 GO:0035374 chondroitin sulfate binding 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.408951782270714 GO:0042166 acetylcholine binding 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.408951782270714 GO:0043121 neurotrophin binding 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.408951782270714 GO:0050815 phosphoserine residue binding 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.408951782270714 GO:0098505 G-rich strand telomeric DNA binding 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.408951782270714 GO:0140135 mechanosensitive monoatomic cation channel activity 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.408951782270714 GO:0005080 protein kinase C binding 5/789 52/18639 0.0961538461538462 2.27149751389295 0.0681232484132114 0.43030368422158 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 3/789 23/18639 0.130434782608696 3.08133575797652 0.0713534464177356 0.444314288351282 GO:0004864 protein phosphatase inhibitor activity 5/789 53/18639 0.0943396226415094 2.22863907023459 0.0727290370708158 0.444314288351282 GO:0004713 protein tyrosine kinase activity 10/789 140/18639 0.0714285714285714 1.68739815317762 0.0737827182280459 0.444314288351282 GO:0008081 phosphoric diester hydrolase activity 7/789 87/18639 0.0804597701149425 1.9007473449587 0.0754526622482005 0.444314288351282 GO:0003953 NAD+ nucleosidase activity 2/789 11/18639 0.181818181818182 4.29519529899758 0.076413960752897 0.444314288351282 GO:0008046 axon guidance receptor activity 2/789 11/18639 0.181818181818182 4.29519529899758 0.076413960752897 0.444314288351282 GO:0015217 ADP transmembrane transporter activity 2/789 11/18639 0.181818181818182 4.29519529899758 0.076413960752897 0.444314288351282 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 2/789 11/18639 0.181818181818182 4.29519529899758 0.076413960752897 0.444314288351282 GO:0048185 activin binding 2/789 11/18639 0.181818181818182 4.29519529899758 0.076413960752897 0.444314288351282 GO:0050786 RAGE receptor binding 2/789 11/18639 0.181818181818182 4.29519529899758 0.076413960752897 0.444314288351282 GO:0070990 snRNP binding 2/789 11/18639 0.181818181818182 4.29519529899758 0.076413960752897 0.444314288351282 GO:0097493 structural molecule activity conferring elasticity 2/789 11/18639 0.181818181818182 4.29519529899758 0.076413960752897 0.444314288351282 GO:1901681 sulfur compound binding 17/789 275/18639 0.0618181818181818 1.46036640165918 0.0769417607106325 0.444439907262733 GO:0003713 transcription coactivator activity 16/789 256/18639 0.0625 1.47647338403042 0.0782156887336639 0.447979671873796 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/789 24/18639 0.125 2.95294676806084 0.0790852495904766 0.447979671873796 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/789 24/18639 0.125 2.95294676806084 0.0790852495904766 0.447979671873796 GO:0005267 potassium channel activity 9/789 124/18639 0.0725806451612903 1.71461425242242 0.0804115830544564 0.452572884114184 GO:0001664 G protein-coupled receptor binding 18/789 297/18639 0.0606060606060606 1.43173176633253 0.0813315289581584 0.453069172659312 GO:0000217 DNA secondary structure binding 4/789 39/18639 0.102564102564103 2.42293068148581 0.0815318101140903 0.453069172659312 GO:0022843 voltage-gated monoatomic cation channel activity 10/789 143/18639 0.0699300699300699 1.65199819192215 0.0823385662939394 0.45467459878037 GO:0030170 pyridoxal phosphate binding 5/789 56/18639 0.0892857142857143 2.10924769147203 0.0875351699059573 0.468969809980866 GO:0008603 cAMP-dependent protein kinase regulator activity 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.468969809980866 GO:0015269 calcium-activated potassium channel activity 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.468969809980866 GO:0015368 calcium:monoatomic cation antiporter activity 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.468969809980866 GO:0043047 single-stranded telomeric DNA binding 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.468969809980866 GO:0045295 gamma-catenin binding 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.468969809980866 GO:0070679 inositol 1,4,5 trisphosphate binding 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.468969809980866 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.468969809980866 GO:0005539 glycosaminoglycan binding 15/789 242/18639 0.0619834710743802 1.46427112465827 0.090750356050076 0.474278646499802 GO:0070279 vitamin B6 binding 5/789 57/18639 0.087719298245614 2.0722433460076 0.0927942529433758 0.480266473945155 GO:0003714 transcription corepressor activity 13/789 204/18639 0.0637254901960784 1.50542384254082 0.0935072753460614 0.480266473945155 GO:0031490 chromatin DNA binding 9/789 128/18639 0.0703125 1.66103255703422 0.093537092305947 0.480266473945155 GO:0004112 cyclic-nucleotide phosphodiesterase activity 3/789 26/18639 0.115384615384615 2.72579701667154 0.0955740372056913 0.482264394635615 GO:0004435 phosphatidylinositol phospholipase C activity 3/789 26/18639 0.115384615384615 2.72579701667154 0.0955740372056913 0.482264394635615 GO:0034237 protein kinase A regulatory subunit binding 3/789 26/18639 0.115384615384615 2.72579701667154 0.0955740372056913 0.482264394635615 GO:0042056 chemoattractant activity 4/789 42/18639 0.0952380952380952 2.24986420423683 0.100716312408348 0.503016378234627 GO:0005516 calmodulin binding 13/789 207/18639 0.0628019323671498 1.4836061056924 0.101723257215578 0.503016378234627 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 2/789 13/18639 0.153846153846154 3.63439602222872 0.102559913737448 0.503016378234627 GO:0071837 HMG box domain binding 2/789 13/18639 0.153846153846154 3.63439602222872 0.102559913737448 0.503016378234627 GO:0140333 glycerophospholipid flippase activity 2/789 13/18639 0.153846153846154 3.63439602222872 0.102559913737448 0.503016378234627 GO:0019207 kinase regulator activity 17/789 287/18639 0.0592334494773519 1.39930578556193 0.103124086654024 0.503016378234627 GO:0004364 glutathione transferase activity 3/789 27/18639 0.111111111111111 2.62484157160963 0.104300382163815 0.503163382086975 GO:0035255 ionotropic glutamate receptor binding 3/789 27/18639 0.111111111111111 2.62484157160963 0.104300382163815 0.503163382086975 GO:0008200 ion channel inhibitor activity 4/789 43/18639 0.0930232558139535 2.19754178088248 0.107534600466455 0.511804990870427 GO:0004867 serine-type endopeptidase inhibitor activity 7/789 95/18639 0.0736842105263158 1.74068441064639 0.107839271808603 0.511804990870427 GO:0005179 hormone activity 9/789 132/18639 0.0681818181818182 1.61069823712409 0.107840459351969 0.511804990870427 GO:0045499 chemorepellent activity 3/789 28/18639 0.107142857142857 2.53109722976643 0.113326832370208 0.52962595828632 GO:0051393 alpha-actinin binding 3/789 28/18639 0.107142857142857 2.53109722976643 0.113326832370208 0.52962595828632 GO:0016248 channel inhibitor activity 4/789 44/18639 0.0909090909090909 2.14759764949879 0.114554850426024 0.52962595828632 GO:0005347 ATP transmembrane transporter activity 2/789 14/18639 0.142857142857143 3.37479630635524 0.116421195841981 0.52962595828632 GO:0034236 protein kinase A catalytic subunit binding 2/789 14/18639 0.142857142857143 3.37479630635524 0.116421195841981 0.52962595828632 GO:0071933 Arp2/3 complex binding 2/789 14/18639 0.142857142857143 3.37479630635524 0.116421195841981 0.52962595828632 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 2/789 14/18639 0.142857142857143 3.37479630635524 0.116421195841981 0.52962595828632 GO:0098847 sequence-specific single stranded DNA binding 2/789 14/18639 0.142857142857143 3.37479630635524 0.116421195841981 0.52962595828632 GO:0005244 voltage-gated monoatomic ion channel activity 11/789 173/18639 0.0635838150289017 1.50207696872459 0.117328757819584 0.531003347245334 GO:0005249 voltage-gated potassium channel activity 7/789 98/18639 0.0714285714285714 1.68739815317762 0.121632034180515 0.541082217813511 GO:0141110 transporter inhibitor activity 4/789 45/18639 0.0888888888888889 2.09987325728771 0.121770727600346 0.541082217813511 GO:0004181 metallocarboxypeptidase activity 3/789 29/18639 0.103448275862069 2.4438180149469 0.122637085814224 0.541082217813511 GO:0004629 phospholipase C activity 3/789 29/18639 0.103448275862069 2.4438180149469 0.122637085814224 0.541082217813511 GO:0043236 laminin binding 3/789 29/18639 0.103448275862069 2.4438180149469 0.122637085814224 0.541082217813511 GO:0022832 voltage-gated channel activity 11/789 175/18639 0.0628571428571429 1.48491037479631 0.124257638400433 0.545491032577902 GO:0004089 carbonate dehydratase activity 2/789 15/18639 0.133333333333333 3.14980988593156 0.130717966941741 0.554446255917142 GO:0004953 icosanoid receptor activity 2/789 15/18639 0.133333333333333 3.14980988593156 0.130717966941741 0.554446255917142 GO:0005041 low-density lipoprotein particle receptor activity 2/789 15/18639 0.133333333333333 3.14980988593156 0.130717966941741 0.554446255917142 GO:0005523 tropomyosin binding 2/789 15/18639 0.133333333333333 3.14980988593156 0.130717966941741 0.554446255917142 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 2/789 15/18639 0.133333333333333 3.14980988593156 0.130717966941741 0.554446255917142 GO:0033130 acetylcholine receptor binding 2/789 15/18639 0.133333333333333 3.14980988593156 0.130717966941741 0.554446255917142 GO:0140776 protein-containing complex destabilizing activity 2/789 15/18639 0.133333333333333 3.14980988593156 0.130717966941741 0.554446255917142 GO:0001968 fibronectin binding 3/789 30/18639 0.1 2.36235741444867 0.132214638233668 0.558098328697886 GO:0003697 single-stranded DNA binding 8/789 121/18639 0.0661157024793388 1.56188919963548 0.141248538256062 0.592552598900066 GO:0140693 molecular condensate scaffold activity 4/789 48/18639 0.0833333333333333 1.96863117870722 0.144524879975113 0.592552598900066 GO:0005024 transforming growth factor beta receptor activity 2/789 16/18639 0.125 2.95294676806084 0.145388639927428 0.592552598900066 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/789 16/18639 0.125 2.95294676806084 0.145388639927428 0.592552598900066 GO:0070411 I-SMAD binding 2/789 16/18639 0.125 2.95294676806084 0.145388639927428 0.592552598900066 GO:0140327 flippase activity 2/789 16/18639 0.125 2.95294676806084 0.145388639927428 0.592552598900066 GO:0140328 floppase activity 2/789 16/18639 0.125 2.95294676806084 0.145388639927428 0.592552598900066 GO:0005178 integrin binding 10/789 161/18639 0.062111801242236 1.46730274189358 0.145776037998194 0.592552598900066 GO:0008235 metalloexopeptidase activity 5/789 66/18639 0.0757575757575758 1.78966470791566 0.146904695926838 0.594388585362967 GO:0035254 glutamate receptor binding 4/789 49/18639 0.0816326530612245 1.928455032203 0.152454936590219 0.614015753789967 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 6/789 86/18639 0.0697674418604651 1.64815633566186 0.156868557367092 0.628514143942968 GO:0031489 myosin V binding 2/789 17/18639 0.117647058823529 2.77924401699843 0.160376049667941 0.628514143942968 GO:0045236 CXCR chemokine receptor binding 2/789 17/18639 0.117647058823529 2.77924401699843 0.160376049667941 0.628514143942968 GO:0070492 oligosaccharide binding 2/789 17/18639 0.117647058823529 2.77924401699843 0.160376049667941 0.628514143942968 GO:1990841 promoter-specific chromatin binding 5/789 68/18639 0.0735294117647059 1.73702751062402 0.160439700224581 0.628514143942968 GO:0032813 tumor necrosis factor receptor superfamily binding 4/789 50/18639 0.08 1.88988593155894 0.160545469419425 0.628514143942968 GO:0019956 chemokine binding 3/789 33/18639 0.0909090909090909 2.14759764949879 0.162384842505534 0.628514143942968 GO:0140311 protein sequestering activity 3/789 33/18639 0.0909090909090909 2.14759764949879 0.162384842505534 0.628514143942968 GO:0008013 beta-catenin binding 7/789 106/18639 0.0660377358490566 1.56004734916422 0.162497392568398 0.628514143942968 GO:0003743 translation initiation factor activity 4/789 51/18639 0.0784313725490196 1.85282934466562 0.168788953983688 0.649985533323148 GO:0042826 histone deacetylase binding 8/789 127/18639 0.062992125984252 1.48809915870782 0.17055217680355 0.653907472635445 GO:0000400 four-way junction DNA binding 2/789 18/18639 0.111111111111111 2.62484157160963 0.175627189771966 0.664658071637011 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/789 18/18639 0.111111111111111 2.62484157160963 0.175627189771966 0.664658071637011 GO:0030228 lipoprotein particle receptor activity 2/789 18/18639 0.111111111111111 2.62484157160963 0.175627189771966 0.664658071637011 GO:0017046 peptide hormone binding 4/789 53/18639 0.0754716981132075 1.78291125618767 0.185704189369832 0.699778018312072 GO:1902936 phosphatidylinositol bisphosphate binding 7/789 111/18639 0.0630630630630631 1.48977494604871 0.19077803701686 0.707930894937277 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/789 19/18639 0.105263157894737 2.48669201520913 0.191092963667579 0.707930894937277 GO:0008381 mechanosensitive monoatomic ion channel activity 2/789 19/18639 0.105263157894737 2.48669201520913 0.191092963667579 0.707930894937277 GO:0046624 sphingolipid transporter activity 2/789 19/18639 0.105263157894737 2.48669201520913 0.191092963667579 0.707930894937277 GO:0003925 G protein activity 4/789 54/18639 0.0740740740740741 1.74989438107309 0.194360471242532 0.714385546495943 GO:0043178 alcohol binding 6/789 92/18639 0.0652173913043478 1.54066787898826 0.194462580424294 0.714385546495943 GO:0005200 structural constituent of cytoskeleton 7/789 112/18639 0.0625 1.47647338403042 0.196660692871099 0.719450368086771 GO:0005261 monoatomic cation channel activity 18/789 341/18639 0.0527859237536657 1.24699218357994 0.19895050352276 0.72480722860159 GO:0001217 DNA-binding transcription repressor activity 15/789 278/18639 0.0539568345323741 1.27465328117734 0.201655534379714 0.731626277625575 GO:0046873 metal ion transmembrane transporter activity 23/789 450/18639 0.0511111111111111 1.20742712294043 0.203256625423542 0.7318836268217 GO:0031491 nucleosome binding 5/789 74/18639 0.0675675675675676 1.59618744219505 0.203796375278514 0.7318836268217 GO:0022829 wide pore channel activity 3/789 37/18639 0.0810810810810811 1.91542493063406 0.205350699759157 0.7318836268217 GO:0042805 actinin binding 3/789 37/18639 0.0810810810810811 1.91542493063406 0.205350699759157 0.7318836268217 GO:0016004 phospholipase activator activity 2/789 20/18639 0.1 2.36235741444867 0.20672794926171 0.7318836268217 GO:0030742 GTP-dependent protein binding 2/789 20/18639 0.1 2.36235741444867 0.20672794926171 0.7318836268217 GO:0000146 microfilament motor activity 3/789 38/18639 0.0789473684210526 1.86501901140684 0.216474061912755 0.75722799346374 GO:0005501 retinoid binding 3/789 38/18639 0.0789473684210526 1.86501901140684 0.216474061912755 0.75722799346374 GO:0019840 isoprenoid binding 3/789 38/18639 0.0789473684210526 1.86501901140684 0.216474061912755 0.75722799346374 GO:0017022 myosin binding 5/789 76/18639 0.0657894736842105 1.5541825095057 0.219046165132263 0.763184654706854 GO:0005123 death receptor binding 2/789 21/18639 0.0952380952380952 2.24986420423683 0.222490176478081 0.766064215481394 GO:0009975 cyclase activity 2/789 21/18639 0.0952380952380952 2.24986420423683 0.222490176478081 0.766064215481394 GO:0070182 DNA polymerase binding 2/789 21/18639 0.0952380952380952 2.24986420423683 0.222490176478081 0.766064215481394 GO:0019208 phosphatase regulator activity 7/789 117/18639 0.0598290598290598 1.41337623086673 0.227089146795167 0.777966930412455 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 3/789 39/18639 0.0769230769230769 1.81719801111436 0.227719249562643 0.777966930412455 GO:0070851 growth factor receptor binding 8/789 139/18639 0.0575539568345324 1.35963016658916 0.236299836678519 0.795909420785188 GO:0015079 potassium ion transmembrane transporter activity 9/789 160/18639 0.05625 1.32882604562738 0.237728714146246 0.795909420785188 GO:0008093 cytoskeletal anchor activity 2/789 22/18639 0.0909090909090909 2.14759764949879 0.238340917007133 0.795909420785188 GO:0061791 GTPase motor activity 3/789 40/18639 0.075 1.7717680608365 0.239071398849202 0.795909420785188 GO:1990606 membrane scission GTPase motor activity 3/789 40/18639 0.075 1.7717680608365 0.239071398849202 0.795909420785188 GO:0004879 nuclear receptor activity 4/789 59/18639 0.0677966101694915 1.60159824708384 0.239316727889851 0.795909420785188 GO:0015459 potassium channel regulator activity 4/789 59/18639 0.0677966101694915 1.60159824708384 0.239316727889851 0.795909420785188 GO:0046332 SMAD binding 5/789 79/18639 0.0632911392405063 1.49516292053713 0.24254019782173 0.802654662693491 GO:0004866 endopeptidase inhibitor activity 9/789 161/18639 0.0559006211180124 1.32057246770422 0.243173280497117 0.802654662693491 GO:0098531 ligand-modulated transcription factor activity 4/789 60/18639 0.0666666666666667 1.57490494296578 0.248588569866682 0.805872412950403 GO:0008083 growth factor activity 9/789 162/18639 0.0555555555555556 1.31242078580482 0.248660684907277 0.805872412950403 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/789 41/18639 0.0731707317073171 1.72855420569415 0.250516034256395 0.805872412950403 GO:0000049 tRNA binding 5/789 80/18639 0.0625 1.47647338403042 0.250517686247314 0.805872412950403 GO:0000295 adenine nucleotide transmembrane transporter activity 2/789 23/18639 0.0869565217391304 2.05422383865102 0.254244485634694 0.805872412950403 GO:0004602 glutathione peroxidase activity 2/789 23/18639 0.0869565217391304 2.05422383865102 0.254244485634694 0.805872412950403 GO:0005283 amino acid:sodium symporter activity 2/789 23/18639 0.0869565217391304 2.05422383865102 0.254244485634694 0.805872412950403 GO:0016849 phosphorus-oxygen lyase activity 2/789 23/18639 0.0869565217391304 2.05422383865102 0.254244485634694 0.805872412950403 GO:0017134 fibroblast growth factor binding 2/789 23/18639 0.0869565217391304 2.05422383865102 0.254244485634694 0.805872412950403 GO:0031681 G-protein beta-subunit binding 2/789 23/18639 0.0869565217391304 2.05422383865102 0.254244485634694 0.805872412950403 GO:0070577 lysine-acetylated histone binding 2/789 23/18639 0.0869565217391304 2.05422383865102 0.254244485634694 0.805872412950403 GO:0140104 molecular carrier activity 13/789 249/18639 0.0522088353413655 1.23335929268404 0.257816337037933 0.814254474529875 GO:0008307 structural constituent of muscle 3/789 42/18639 0.0714285714285714 1.68739815317762 0.262039089783168 0.820787370716169 GO:0019955 cytokine binding 8/789 144/18639 0.0555555555555556 1.31242078580482 0.265975930011551 0.820787370716169 GO:0005085 guanyl-nucleotide exchange factor activity 12/789 230/18639 0.0521739130434783 1.23253430319061 0.269655738444138 0.820787370716169 GO:0015149 hexose transmembrane transporter activity 2/789 24/18639 0.0833333333333333 1.96863117870722 0.270168052547805 0.820787370716169 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/789 24/18639 0.0833333333333333 1.96863117870722 0.270168052547805 0.820787370716169 GO:0030215 semaphorin receptor binding 2/789 24/18639 0.0833333333333333 1.96863117870722 0.270168052547805 0.820787370716169 GO:0035035 histone acetyltransferase binding 2/789 24/18639 0.0833333333333333 1.96863117870722 0.270168052547805 0.820787370716169 GO:0050699 WW domain binding 2/789 24/18639 0.0833333333333333 1.96863117870722 0.270168052547805 0.820787370716169 GO:0055056 D-glucose transmembrane transporter activity 2/789 24/18639 0.0833333333333333 1.96863117870722 0.270168052547805 0.820787370716169 GO:0060229 lipase activator activity 2/789 24/18639 0.0833333333333333 1.96863117870722 0.270168052547805 0.820787370716169 GO:0140033 acetylation-dependent protein binding 2/789 24/18639 0.0833333333333333 1.96863117870722 0.270168052547805 0.820787370716169 GO:0005245 voltage-gated calcium channel activity 3/789 43/18639 0.0697674418604651 1.64815633566186 0.273626926481921 0.825582273027928 GO:0048156 tau protein binding 3/789 43/18639 0.0697674418604651 1.64815633566186 0.273626926481921 0.825582273027928 GO:0015085 calcium ion transmembrane transporter activity 8/789 147/18639 0.054421768707483 1.28563668813533 0.284281462306476 0.845722313766044 GO:0019887 protein kinase regulator activity 13/789 255/18639 0.0509803921568627 1.20433907403265 0.285237259590281 0.845722313766044 GO:0030547 signaling receptor inhibitor activity 3/789 44/18639 0.0681818181818182 1.61069823712409 0.285266346681133 0.845722313766044 GO:0008483 transaminase activity 2/789 25/18639 0.08 1.88988593155894 0.286081466046145 0.845722313766044 GO:0015271 outward rectifier potassium channel activity 2/789 25/18639 0.08 1.88988593155894 0.286081466046145 0.845722313766044 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/789 25/18639 0.08 1.88988593155894 0.286081466046145 0.845722313766044 GO:0030414 peptidase inhibitor activity 9/789 169/18639 0.0532544378698225 1.25806016154071 0.288147522268257 0.848971558897749 GO:0004715 non-membrane spanning protein tyrosine kinase activity 3/789 45/18639 0.0666666666666667 1.57490494296578 0.296944605186904 0.860773768610417 GO:0008009 chemokine activity 3/789 45/18639 0.0666666666666667 1.57490494296578 0.296944605186904 0.860773768610417 GO:0019888 protein phosphatase regulator activity 6/789 107/18639 0.0560747663551402 1.32468640062542 0.300044484302246 0.860773768610417 GO:0005227 calcium-activated cation channel activity 2/789 26/18639 0.0769230769230769 1.81719801111436 0.301957085116183 0.860773768610417 GO:0008066 glutamate receptor activity 2/789 26/18639 0.0769230769230769 1.81719801111436 0.301957085116183 0.860773768610417 GO:0015145 monosaccharide transmembrane transporter activity 2/789 26/18639 0.0769230769230769 1.81719801111436 0.301957085116183 0.860773768610417 GO:0015216 purine nucleotide transmembrane transporter activity 2/789 26/18639 0.0769230769230769 1.81719801111436 0.301957085116183 0.860773768610417 GO:0019865 immunoglobulin binding 2/789 26/18639 0.0769230769230769 1.81719801111436 0.301957085116183 0.860773768610417 GO:0043548 phosphatidylinositol 3-kinase binding 2/789 26/18639 0.0769230769230769 1.81719801111436 0.301957085116183 0.860773768610417 GO:0070006 metalloaminopeptidase activity 2/789 26/18639 0.0769230769230769 1.81719801111436 0.301957085116183 0.860773768610417 GO:0004180 carboxypeptidase activity 3/789 46/18639 0.0652173913043478 1.54066787898826 0.308649417737319 0.877003847162998 GO:0005104 fibroblast growth factor receptor binding 2/789 27/18639 0.0740740740740741 1.74989438107309 0.317769621352372 0.880000682439051 GO:0023026 MHC class II protein complex binding 2/789 27/18639 0.0740740740740741 1.74989438107309 0.317769621352372 0.880000682439051 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2/789 27/18639 0.0740740740740741 1.74989438107309 0.317769621352372 0.880000682439051 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 5/789 89/18639 0.0561797752808989 1.32716708676892 0.324681213698826 0.880000682439051 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 5/789 89/18639 0.0561797752808989 1.32716708676892 0.324681213698826 0.880000682439051 GO:0140793 histone H2AXY142 phosphatase activity 5/789 90/18639 0.0555555555555556 1.31242078580482 0.333099708888883 0.880000682439051 GO:0005242 inward rectifier potassium channel activity 2/789 28/18639 0.0714285714285714 1.68739815317762 0.333495989735615 0.880000682439051 GO:0046625 sphingolipid binding 2/789 28/18639 0.0714285714285714 1.68739815317762 0.333495989735615 0.880000682439051 GO:0051119 sugar transmembrane transporter activity 2/789 28/18639 0.0714285714285714 1.68739815317762 0.333495989735615 0.880000682439051 GO:0141052 histone H3 demethylase activity 2/789 28/18639 0.0714285714285714 1.68739815317762 0.333495989735615 0.880000682439051 GO:0016829 lyase activity 10/789 200/18639 0.05 1.18117870722433 0.340683804717546 0.880000682439051 GO:0001222 transcription corepressor binding 3/789 49/18639 0.0612244897959184 1.44634127415225 0.343807360629572 0.880000682439051 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 13/789 268/18639 0.0485074626865672 1.14591964133704 0.347326214863245 0.880000682439051 GO:0005416 amino acid:monoatomic cation symporter activity 2/789 29/18639 0.0689655172413793 1.6292120099646 0.349115167803866 0.880000682439051 GO:0051861 glycolipid binding 2/789 29/18639 0.0689655172413793 1.6292120099646 0.349115167803866 0.880000682439051 GO:0004935 adrenergic receptor activity 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0005337 nucleoside transmembrane transporter activity 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0005345 purine nucleobase transmembrane transporter activity 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0005528 FK506 binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0015643 toxic substance binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0030957 Tat protein binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0031434 mitogen-activated protein kinase kinase binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0031996 thioesterase binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0032356 oxidized DNA binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0035256 G protein-coupled glutamate receptor binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0042975 peroxisome proliferator activated receptor binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0043208 glycosphingolipid binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0070097 delta-catenin binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0071723 lipopeptide binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.880000682439051 GO:0042393 histone binding 12/789 247/18639 0.048582995951417 1.1477040070196 0.354155313807345 0.880000682439051 GO:0061134 peptidase regulator activity 11/789 226/18639 0.0486725663716814 1.14981998048387 0.361361596896944 0.880000682439051 GO:0042379 chemokine receptor binding 4/789 72/18639 0.0555555555555556 1.31242078580482 0.363678479052439 0.880000682439051 GO:0042277 peptide binding 12/789 249/18639 0.0481927710843374 1.13848550093912 0.364418970053059 0.880000682439051 GO:0015215 nucleotide transmembrane transporter activity 2/789 30/18639 0.0666666666666667 1.57490494296578 0.364608062773166 0.880000682439051 GO:0016769 transferase activity, transferring nitrogenous groups 2/789 30/18639 0.0666666666666667 1.57490494296578 0.364608062773166 0.880000682439051 GO:0022839 monoatomic ion-gated channel activity 2/789 30/18639 0.0666666666666667 1.57490494296578 0.364608062773166 0.880000682439051 GO:0032452 histone demethylase activity 2/789 30/18639 0.0666666666666667 1.57490494296578 0.364608062773166 0.880000682439051 GO:0098918 structural constituent of synapse 2/789 30/18639 0.0666666666666667 1.57490494296578 0.364608062773166 0.880000682439051 GO:0022836 gated channel activity 15/789 318/18639 0.0471698113207547 1.1143195351173 0.370857365079694 0.880000682439051 GO:0061135 endopeptidase regulator activity 9/789 184/18639 0.0489130434782609 1.1555009092412 0.377158712908717 0.880000682439051 GO:0002162 dystroglycan binding 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0004016 adenylate cyclase activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0004954 prostanoid receptor activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0005114 type II transforming growth factor beta receptor binding 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0008432 JUN kinase binding 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0010854 adenylate cyclase regulator activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0015205 nucleobase transmembrane transporter activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0019215 intermediate filament binding 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0034056 estrogen response element binding 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0043522 leucine zipper domain binding 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0048407 platelet-derived growth factor binding 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0050998 nitric-oxide synthase binding 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.880000682439051 GO:0005164 tumor necrosis factor receptor binding 2/789 31/18639 0.0645161290322581 1.52410155770882 0.379957386189692 0.880000682439051 GO:0047499 calcium-independent phospholipase A2 activity 2/789 31/18639 0.0645161290322581 1.52410155770882 0.379957386189692 0.880000682439051 GO:0070325 lipoprotein particle receptor binding 2/789 31/18639 0.0645161290322581 1.52410155770882 0.379957386189692 0.880000682439051 GO:0140457 protein demethylase activity 2/789 31/18639 0.0645161290322581 1.52410155770882 0.379957386189692 0.880000682439051 GO:0005126 cytokine receptor binding 13/789 275/18639 0.0472727272727273 1.11675077773937 0.381780491697852 0.880000682439051 GO:1901981 phosphatidylinositol phosphate binding 9/789 185/18639 0.0486486486486487 1.14925495838043 0.383211201896503 0.880000682439051 GO:1901505 carbohydrate derivative transmembrane transporter activity 3/789 53/18639 0.0566037735849057 1.33718344214076 0.390393317723501 0.880000682439051 GO:0019003 GDP binding 4/789 75/18639 0.0533333333333333 1.25992395437262 0.39274452353008 0.880000682439051 GO:0031369 translation initiation factor binding 2/789 32/18639 0.0625 1.47647338403042 0.395147535714598 0.880000682439051 GO:0042910 xenobiotic transmembrane transporter activity 2/789 32/18639 0.0625 1.47647338403042 0.395147535714598 0.880000682439051 GO:0047498 calcium-dependent phospholipase A2 activity 2/789 32/18639 0.0625 1.47647338403042 0.395147535714598 0.880000682439051 GO:0004725 protein tyrosine phosphatase activity 5/789 98/18639 0.0510204081632653 1.20528439512687 0.400787213286663 0.880000682439051 GO:0015485 cholesterol binding 3/789 54/18639 0.0555555555555556 1.31242078580482 0.401924661634147 0.880000682439051 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3/789 54/18639 0.0555555555555556 1.31242078580482 0.401924661634147 0.880000682439051 GO:0050661 NADP binding 3/789 54/18639 0.0555555555555556 1.31242078580482 0.401924661634147 0.880000682439051 GO:0005125 cytokine activity 11/789 234/18639 0.047008547008547 1.110509895681 0.404730690010887 0.880000682439051 GO:0003720 telomerase activity 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:0004859 phospholipase inhibitor activity 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:0005025 transforming growth factor beta receptor activity, type I 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:0005026 transforming growth factor beta receptor activity, type II 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:0005165 neurotrophin receptor binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:0005527 macrolide binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:0008179 adenylate cyclase binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:0008504 monoamine transmembrane transporter activity 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:0016208 AMP binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:0016361 activin receptor activity, type I 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:0016362 activin receptor activity, type II 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:0017002 activin receptor activity 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:0035251 UDP-glucosyltransferase activity 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:0035497 cAMP response element binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:0070410 co-SMAD binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:1990459 transferrin receptor binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.880000682439051 GO:0051082 unfolded protein binding 6/789 121/18639 0.0495867768595041 1.17141689972661 0.405922866045348 0.880000682439051 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/789 33/18639 0.0606060606060606 1.43173176633253 0.41016448366357 0.884826576551877 GO:0071889 14-3-3 protein binding 2/789 33/18639 0.0606060606060606 1.43173176633253 0.41016448366357 0.884826576551877 GO:0140313 molecular sequestering activity 3/789 55/18639 0.0545454545454545 1.28855858969927 0.413393076065079 0.88654239810168 GO:0015035 protein-disulfide reductase activity 2/789 34/18639 0.0588235294117647 1.38962200849922 0.424995671942199 0.88654239810168 GO:0016831 carboxy-lyase activity 2/789 34/18639 0.0588235294117647 1.38962200849922 0.424995671942199 0.88654239810168 GO:0030332 cyclin binding 2/789 34/18639 0.0588235294117647 1.38962200849922 0.424995671942199 0.88654239810168 GO:0090482 vitamin transmembrane transporter activity 2/789 34/18639 0.0588235294117647 1.38962200849922 0.424995671942199 0.88654239810168 GO:0003964 RNA-directed DNA polymerase activity 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.88654239810168 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.88654239810168 GO:0005035 death receptor activity 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.88654239810168 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.88654239810168 GO:0017154 semaphorin receptor activity 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.88654239810168 GO:0035325 Toll-like receptor binding 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.88654239810168 GO:0043560 insulin receptor substrate binding 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.88654239810168 GO:0045159 myosin II binding 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.88654239810168 GO:0046974 histone H3K9 methyltransferase activity 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.88654239810168 GO:0061459 L-arginine transmembrane transporter activity 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.88654239810168 GO:0070123 transforming growth factor beta receptor activity, type III 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.88654239810168 GO:0089720 caspase binding 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.88654239810168 GO:1901338 catecholamine binding 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.88654239810168 GO:0015370 solute:sodium symporter activity 4/789 79/18639 0.0506329113924051 1.19613033642971 0.431154446457195 0.88654239810168 GO:0016835 carbon-oxygen lyase activity 4/789 79/18639 0.0506329113924051 1.19613033642971 0.431154446457195 0.88654239810168 GO:0008238 exopeptidase activity 5/789 102/18639 0.0490196078431373 1.15801834041601 0.434446199022772 0.889389547571508 GO:0005216 monoatomic ion channel activity 20/789 448/18639 0.0446428571428571 1.05462384573601 0.435942930456686 0.889389547571508 GO:0015932 nucleobase-containing compound transmembrane transporter activity 3/789 57/18639 0.0526315789473684 1.24334600760456 0.436110933357821 0.889389547571508 GO:0004623 phospholipase A2 activity 2/789 35/18639 0.0571428571428571 1.3499185225421 0.439629913036486 0.889389547571508 GO:0005154 epidermal growth factor receptor binding 2/789 35/18639 0.0571428571428571 1.3499185225421 0.439629913036486 0.889389547571508 GO:0005343 organic acid:sodium symporter activity 2/789 35/18639 0.0571428571428571 1.3499185225421 0.439629913036486 0.889389547571508 GO:0061631 ubiquitin conjugating enzyme activity 2/789 35/18639 0.0571428571428571 1.3499185225421 0.439629913036486 0.889389547571508 GO:0015101 organic cation transmembrane transporter activity 4/789 81/18639 0.0493827160493827 1.16659625404873 0.450121454072127 0.896421484747643 GO:0030971 receptor tyrosine kinase binding 4/789 81/18639 0.0493827160493827 1.16659625404873 0.450121454072127 0.896421484747643 GO:0004705 JUN kinase activity 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.896421484747643 GO:0008494 translation activator activity 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.896421484747643 GO:0008559 ABC-type xenobiotic transporter activity 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.896421484747643 GO:0019763 immunoglobulin receptor activity 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.896421484747643 GO:0019992 diacylglycerol binding 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.896421484747643 GO:0031404 chloride ion binding 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.896421484747643 GO:0032036 myosin heavy chain binding 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.896421484747643 GO:0098821 BMP receptor activity 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.896421484747643 GO:1901474 azole transmembrane transporter activity 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.896421484747643 GO:0045309 protein phosphorylated amino acid binding 3/789 59/18639 0.0508474576271186 1.20119868531288 0.45849080413605 0.902589520249891 GO:0023023 MHC protein complex binding 2/789 37/18639 0.0540540540540541 1.27694995375604 0.46826910227659 0.90953688776137 GO:0030551 cyclic nucleotide binding 2/789 37/18639 0.0540540540540541 1.27694995375604 0.46826910227659 0.90953688776137 GO:0003774 cytoskeletal motor activity 7/789 153/18639 0.0457516339869281 1.08081711772161 0.471693485267375 0.90953688776137 GO:0004129 cytochrome-c oxidase activity 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.90953688776137 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.90953688776137 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.90953688776137 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.90953688776137 GO:0016846 carbon-sulfur lyase activity 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.90953688776137 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.90953688776137 GO:0030553 cGMP binding 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.90953688776137 GO:0031005 filamin binding 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.90953688776137 GO:0050780 dopamine receptor binding 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.90953688776137 GO:0051371 muscle alpha-actinin binding 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.90953688776137 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 3/789 61/18639 0.0491803278688525 1.16181512186 0.480483234589737 0.90953688776137 GO:0005262 calcium channel activity 6/789 131/18639 0.0458015267175573 1.0819957623429 0.481149057644493 0.90953688776137 GO:0005319 lipid transporter activity 8/789 178/18639 0.0449438202247191 1.06173366941513 0.482499190121094 0.90953688776137 GO:0004620 phospholipase activity 5/789 109/18639 0.0458715596330275 1.08365019011407 0.492200589262911 0.90953688776137 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0004707 MAP kinase activity 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0004708 MAP kinase kinase activity 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0005159 insulin-like growth factor receptor binding 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0008142 oxysterol binding 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0015378 sodium:chloride symporter activity 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0017070 U6 snRNA binding 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0019841 retinol binding 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0022841 potassium ion leak channel activity 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0022858 alanine transmembrane transporter activity 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0030275 LRR domain binding 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0043023 ribosomal large subunit binding 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0055102 lipase inhibitor activity 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.90953688776137 GO:0004177 aminopeptidase activity 2/789 40/18639 0.05 1.18117870722433 0.50953998072771 0.90953688776137 GO:0015036 disulfide oxidoreductase activity 2/789 40/18639 0.05 1.18117870722433 0.50953998072771 0.90953688776137 GO:0015144 carbohydrate transmembrane transporter activity 2/789 40/18639 0.05 1.18117870722433 0.50953998072771 0.90953688776137 GO:0030331 nuclear estrogen receptor binding 2/789 40/18639 0.05 1.18117870722433 0.50953998072771 0.90953688776137 GO:0032451 demethylase activity 2/789 40/18639 0.05 1.18117870722433 0.50953998072771 0.90953688776137 GO:0008237 metallopeptidase activity 8/789 184/18639 0.0434782608695652 1.02711191932551 0.520178795200132 0.90953688776137 GO:0004550 nucleoside diphosphate kinase activity 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.90953688776137 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.90953688776137 GO:0005092 GDP-dissociation inhibitor activity 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.90953688776137 GO:0008429 phosphatidylethanolamine binding 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.90953688776137 GO:0019198 transmembrane receptor protein phosphatase activity 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.90953688776137 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.90953688776137 GO:0030548 acetylcholine receptor regulator activity 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.90953688776137 GO:0038191 neuropilin binding 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.90953688776137 GO:0045125 bioactive lipid receptor activity 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.90953688776137 GO:0051787 misfolded protein binding 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.90953688776137 GO:1990226 histone methyltransferase binding 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.90953688776137 GO:0001530 lipopolysaccharide binding 2/789 41/18639 0.0487804878048781 1.15236947046277 0.522823260033932 0.90953688776137 GO:0008227 G protein-coupled amine receptor activity 2/789 41/18639 0.0487804878048781 1.15236947046277 0.522823260033932 0.90953688776137 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/789 41/18639 0.0487804878048781 1.15236947046277 0.522823260033932 0.90953688776137 GO:0017080 sodium channel regulator activity 2/789 41/18639 0.0487804878048781 1.15236947046277 0.522823260033932 0.90953688776137 GO:0042169 SH2 domain binding 2/789 41/18639 0.0487804878048781 1.15236947046277 0.522823260033932 0.90953688776137 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/789 41/18639 0.0487804878048781 1.15236947046277 0.522823260033932 0.90953688776137 GO:0140828 metal cation:monoatomic cation antiporter activity 2/789 41/18639 0.0487804878048781 1.15236947046277 0.522823260033932 0.90953688776137 GO:0038024 cargo receptor activity 3/789 65/18639 0.0461538461538462 1.09031880666862 0.523139098313772 0.90953688776137 GO:0003924 GTPase activity 14/789 331/18639 0.0422960725075529 0.999184404902761 0.540027931961224 0.920699416386187 GO:0004970 glutamate-gated receptor activity 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.920699416386187 GO:0008409 5'-3' exonuclease activity 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.920699416386187 GO:0008525 phosphatidylcholine transporter activity 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.920699416386187 GO:0015280 ligand-gated sodium channel activity 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.920699416386187 GO:0015373 monoatomic anion:sodium symporter activity 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.920699416386187 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.920699416386187 GO:0017075 syntaxin-1 binding 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.920699416386187 GO:0031690 adrenergic receptor binding 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.920699416386187 GO:0035615 clathrin adaptor activity 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.920699416386187 GO:0099602 neurotransmitter receptor regulator activity 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.920699416386187 GO:0015081 sodium ion transmembrane transporter activity 7/789 164/18639 0.0426829268292683 1.00832328665492 0.545323018355171 0.922716731814758 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/789 43/18639 0.0465116279069767 1.09877089044124 0.548654446208155 0.922716731814758 GO:0032934 sterol binding 3/789 68/18639 0.0441176470588235 1.04221650637441 0.553835235996295 0.922716731814758 GO:1990782 protein tyrosine kinase binding 5/789 117/18639 0.0427350427350427 1.00955445061909 0.555340087013737 0.922716731814758 GO:0019902 phosphatase binding 8/789 190/18639 0.0421052631578947 0.99467680608365 0.556866786806088 0.922716731814758 GO:0051213 dioxygenase activity 4/789 93/18639 0.043010752688172 1.01606770513921 0.558555476396716 0.922716731814758 GO:0051219 phosphoprotein binding 4/789 93/18639 0.043010752688172 1.01606770513921 0.558555476396716 0.922716731814758 GO:0015245 fatty acid transmembrane transporter activity 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.922716731814758 GO:0016918 retinal binding 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.922716731814758 GO:0022840 leak channel activity 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.922716731814758 GO:0022842 narrow pore channel activity 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.922716731814758 GO:0030506 ankyrin binding 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.922716731814758 GO:0031420 alkali metal ion binding 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.922716731814758 GO:0042577 lipid phosphatase activity 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.922716731814758 GO:0042800 histone H3K4 methyltransferase activity 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.922716731814758 GO:0046527 glucosyltransferase activity 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.922716731814758 GO:0097001 ceramide binding 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.922716731814758 GO:0043014 alpha-tubulin binding 2/789 44/18639 0.0454545454545455 1.0737988247494 0.561196736661823 0.922716731814758 GO:0140303 intramembrane lipid transporter activity 2/789 45/18639 0.0444444444444444 1.04993662864385 0.57348753347461 0.933032998620467 GO:0019903 protein phosphatase binding 6/789 144/18639 0.0416666666666667 0.984315589353612 0.573964793252787 0.933032998620467 GO:0001614 purinergic nucleotide receptor activity 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.933032998620467 GO:0001972 retinoic acid binding 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.933032998620467 GO:0005326 neurotransmitter transmembrane transporter activity 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.933032998620467 GO:0010851 cyclase regulator activity 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.933032998620467 GO:0015095 magnesium ion transmembrane transporter activity 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.933032998620467 GO:0015464 acetylcholine receptor activity 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.933032998620467 GO:0016502 nucleotide receptor activity 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.933032998620467 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.933032998620467 GO:0043024 ribosomal small subunit binding 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.933032998620467 GO:0015293 symporter activity 6/789 146/18639 0.0410958904109589 0.970831814156987 0.587515513994201 0.943234721299787 GO:0005248 voltage-gated sodium channel activity 1/789 21/18639 0.0476190476190476 1.12493210211841 0.596994094206349 0.943234721299787 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/789 21/18639 0.0476190476190476 1.12493210211841 0.596994094206349 0.943234721299787 GO:0015174 basic amino acid transmembrane transporter activity 1/789 21/18639 0.0476190476190476 1.12493210211841 0.596994094206349 0.943234721299787 GO:0035613 RNA stem-loop binding 1/789 21/18639 0.0476190476190476 1.12493210211841 0.596994094206349 0.943234721299787 GO:0051428 peptide hormone receptor binding 1/789 21/18639 0.0476190476190476 1.12493210211841 0.596994094206349 0.943234721299787 GO:0072542 protein phosphatase activator activity 1/789 21/18639 0.0476190476190476 1.12493210211841 0.596994094206349 0.943234721299787 GO:0140312 cargo adaptor activity 1/789 21/18639 0.0476190476190476 1.12493210211841 0.596994094206349 0.943234721299787 GO:0005504 fatty acid binding 2/789 47/18639 0.0425531914893617 1.00525847423348 0.597310370208066 0.943234721299787 GO:0043495 protein-membrane adaptor activity 2/789 47/18639 0.0425531914893617 1.00525847423348 0.597310370208066 0.943234721299787 GO:0140938 histone H3 methyltransferase activity 2/789 47/18639 0.0425531914893617 1.00525847423348 0.597310370208066 0.943234721299787 GO:0019209 kinase activator activity 6/789 148/18639 0.0405405405405405 0.957712465317028 0.600840091520394 0.94710520710037 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/789 48/18639 0.0416666666666667 0.984315589353612 0.608841607778131 0.950892298526713 GO:0032266 phosphatidylinositol-3-phosphate binding 2/789 48/18639 0.0416666666666667 0.984315589353612 0.608841607778131 0.950892298526713 GO:0003684 damaged DNA binding 3/789 74/18639 0.0405405405405405 0.957712465317028 0.611542577833531 0.950892298526713 GO:0019842 vitamin binding 6/789 150/18639 0.04 0.944942965779468 0.613929625950252 0.950892298526713 GO:0015377 chloride:monoatomic cation symporter activity 1/789 22/18639 0.0454545454545455 1.0737988247494 0.614072816930121 0.950892298526713 GO:0031683 G-protein beta/gamma-subunit complex binding 1/789 22/18639 0.0454545454545455 1.0737988247494 0.614072816930121 0.950892298526713 GO:0033691 sialic acid binding 1/789 22/18639 0.0454545454545455 1.0737988247494 0.614072816930121 0.950892298526713 GO:0034062 5'-3' RNA polymerase activity 1/789 22/18639 0.0454545454545455 1.0737988247494 0.614072816930121 0.950892298526713 GO:0050321 tau-protein kinase activity 1/789 22/18639 0.0454545454545455 1.0737988247494 0.614072816930121 0.950892298526713 GO:0097747 RNA polymerase activity 1/789 22/18639 0.0454545454545455 1.0737988247494 0.614072816930121 0.950892298526713 GO:0005543 phospholipid binding 20/789 497/18639 0.0402414486921529 0.950646846860632 0.624810841794057 0.957306929983904 GO:0043021 ribonucleoprotein complex binding 7/789 177/18639 0.0395480225988701 0.934265644132242 0.626220805630856 0.957306929983904 GO:0019001 guanyl nucleotide binding 16/789 400/18639 0.04 0.944942965779468 0.628129695209392 0.957306929983904 GO:0032561 guanyl ribonucleotide binding 16/789 400/18639 0.04 0.944942965779468 0.628129695209392 0.957306929983904 GO:0005158 insulin receptor binding 1/789 23/18639 0.0434782608695652 1.02711191932551 0.630428650170822 0.957306929983904 GO:0016493 C-C chemokine receptor activity 1/789 23/18639 0.0434782608695652 1.02711191932551 0.630428650170822 0.957306929983904 GO:0099186 structural constituent of postsynapse 1/789 23/18639 0.0434782608695652 1.02711191932551 0.630428650170822 0.957306929983904 GO:0140103 catalytic activity, acting on a glycoprotein 1/789 23/18639 0.0434782608695652 1.02711191932551 0.630428650170822 0.957306929983904 GO:0015605 organophosphate ester transmembrane transporter activity 2/789 50/18639 0.04 0.944942965779468 0.63114527471056 0.957306929983904 GO:0015171 amino acid transmembrane transporter activity 4/789 102/18639 0.0392156862745098 0.926414672332811 0.631766252465557 0.957306929983904 GO:0003724 RNA helicase activity 3/789 77/18639 0.038961038961039 0.920398992642339 0.638451090844878 0.957306929983904 GO:0141003 histone H2AX kinase activity 14/789 354/18639 0.0395480225988701 0.934265644132242 0.641301707585408 0.957306929983904 GO:0005272 sodium channel activity 2/789 51/18639 0.0392156862745098 0.926414672332811 0.641919584840002 0.957306929983904 GO:0016830 carbon-carbon lyase activity 2/789 51/18639 0.0392156862745098 0.926414672332811 0.641919584840002 0.957306929983904 GO:0035591 signaling adaptor activity 5/789 129/18639 0.0387596899224806 0.915642408701035 0.642092606053687 0.957306929983904 GO:0000287 magnesium ion binding 9/789 230/18639 0.0391304347826087 0.924400727392958 0.642417550411858 0.957306929983904 GO:0005315 phosphate transmembrane transporter activity 1/789 24/18639 0.0416666666666667 0.984315589353612 0.646092154415301 0.957306929983904 GO:0005540 hyaluronic acid binding 1/789 24/18639 0.0416666666666667 0.984315589353612 0.646092154415301 0.957306929983904 GO:0019957 C-C chemokine binding 1/789 24/18639 0.0416666666666667 0.984315589353612 0.646092154415301 0.957306929983904 GO:0030552 cAMP binding 1/789 24/18639 0.0416666666666667 0.984315589353612 0.646092154415301 0.957306929983904 GO:0050431 transforming growth factor beta binding 1/789 24/18639 0.0416666666666667 0.984315589353612 0.646092154415301 0.957306929983904 GO:0070300 phosphatidic acid binding 1/789 24/18639 0.0416666666666667 0.984315589353612 0.646092154415301 0.957306929983904 GO:0016298 lipase activity 5/789 130/18639 0.0384615384615385 0.908599005557181 0.648827012625779 0.957306929983904 GO:0140996 histone H3 kinase activity 14/789 357/18639 0.0392156862745098 0.926414672332811 0.653652714347377 0.957306929983904 GO:0008186 ATP-dependent activity, acting on RNA 3/789 79/18639 0.0379746835443038 0.897097752322279 0.655650112018692 0.957306929983904 GO:0033293 monocarboxylic acid binding 3/789 79/18639 0.0379746835443038 0.897097752322279 0.655650112018692 0.957306929983904 GO:0000030 mannosyltransferase activity 1/789 25/18639 0.04 0.944942965779468 0.661092599764016 0.957306929983904 GO:0003707 nuclear steroid receptor activity 1/789 25/18639 0.04 0.944942965779468 0.661092599764016 0.957306929983904 GO:0005251 delayed rectifier potassium channel activity 1/789 25/18639 0.04 0.944942965779468 0.661092599764016 0.957306929983904 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/789 25/18639 0.04 0.944942965779468 0.661092599764016 0.957306929983904 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/789 25/18639 0.04 0.944942965779468 0.661092599764016 0.957306929983904 GO:0019211 phosphatase activator activity 1/789 25/18639 0.04 0.944942965779468 0.661092599764016 0.957306929983904 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/789 25/18639 0.04 0.944942965779468 0.661092599764016 0.957306929983904 GO:0019707 protein-cysteine S-acyltransferase activity 1/789 25/18639 0.04 0.944942965779468 0.661092599764016 0.957306929983904 GO:0120020 cholesterol transfer activity 1/789 25/18639 0.04 0.944942965779468 0.661092599764016 0.957306929983904 GO:0035091 phosphatidylinositol binding 11/789 284/18639 0.0387323943661972 0.914997590103358 0.661262939717742 0.957306929983904 GO:0005544 calcium-dependent phospholipid binding 2/789 53/18639 0.0377358490566038 0.891455628093837 0.662720583191422 0.957306929983904 GO:0016860 intramolecular oxidoreductase activity 2/789 53/18639 0.0377358490566038 0.891455628093837 0.662720583191422 0.957306929983904 GO:0035173 histone kinase activity 14/789 360/18639 0.0388888888888889 0.918694550063371 0.665775344938051 0.957306929983904 GO:0017069 snRNA binding 2/789 54/18639 0.037037037037037 0.874947190536544 0.672751195559009 0.957306929983904 GO:0051287 NAD binding 2/789 54/18639 0.037037037037037 0.874947190536544 0.672751195559009 0.957306929983904 GO:0001637 G protein-coupled chemoattractant receptor activity 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.957306929983904 GO:0004529 DNA exonuclease activity 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.957306929983904 GO:0004950 chemokine receptor activity 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.957306929983904 GO:0005160 transforming growth factor beta receptor binding 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.957306929983904 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.957306929983904 GO:0008157 protein phosphatase 1 binding 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.957306929983904 GO:0030507 spectrin binding 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.957306929983904 GO:0050681 nuclear androgen receptor binding 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.957306929983904 GO:0050750 low-density lipoprotein particle receptor binding 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.957306929983904 GO:0070412 R-SMAD binding 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.957306929983904 GO:0097602 cullin family protein binding 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.957306929983904 GO:0005496 steroid binding 4/789 108/18639 0.037037037037037 0.874947190536544 0.676002615706174 0.957306929983904 GO:0015297 antiporter activity 5/789 135/18639 0.037037037037037 0.874947190536544 0.681279399321061 0.959955558395056 GO:0030695 GTPase regulator activity 19/789 489/18639 0.0388548057259714 0.917889383937111 0.682772985560341 0.959955558395056 GO:0060589 nucleoside-triphosphatase regulator activity 19/789 490/18639 0.0387755102040816 0.916016140296423 0.686138797995382 0.959955558395056 GO:0002020 protease binding 5/789 136/18639 0.0367647058823529 0.868513755312011 0.687522404354004 0.959955558395056 GO:0099094 ligand-gated monoatomic cation channel activity 5/789 136/18639 0.0367647058823529 0.868513755312011 0.687522404354004 0.959955558395056 GO:0140789 histone phosphatase activity 5/789 136/18639 0.0367647058823529 0.868513755312011 0.687522404354004 0.959955558395056 GO:0030165 PDZ domain binding 3/789 83/18639 0.036144578313253 0.853864125704338 0.688260877685376 0.959955558395056 GO:0005385 zinc ion transmembrane transporter activity 1/789 27/18639 0.037037037037037 0.874947190536544 0.68921526646522 0.959955558395056 GO:0008395 steroid hydroxylase activity 1/789 27/18639 0.037037037037037 0.874947190536544 0.68921526646522 0.959955558395056 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/789 27/18639 0.037037037037037 0.874947190536544 0.68921526646522 0.959955558395056 GO:0004222 metalloendopeptidase activity 4/789 110/18639 0.0363636363636364 0.859039059799516 0.68989972363016 0.959955558395056 GO:0170055 lipid transmembrane transporter activity 2/789 56/18639 0.0357142857142857 0.84369907658881 0.692084493947955 0.961471812794786 GO:0016922 nuclear receptor binding 5/789 137/18639 0.0364963503649635 0.862174238849879 0.693682049898915 0.962168783272112 GO:0016504 peptidase activator activity 2/789 57/18639 0.0350877192982456 0.828897338403042 0.70139262342396 0.96661201856456 GO:0019789 SUMO transferase activity 1/789 28/18639 0.0357142857142857 0.84369907658881 0.702390054492243 0.96661201856456 GO:0046966 nuclear thyroid hormone receptor binding 1/789 28/18639 0.0357142857142857 0.84369907658881 0.702390054492243 0.96661201856456 GO:0050698 proteoglycan sulfotransferase activity 1/789 28/18639 0.0357142857142857 0.84369907658881 0.702390054492243 0.96661201856456 GO:0051959 dynein light intermediate chain binding 1/789 28/18639 0.0357142857142857 0.84369907658881 0.702390054492243 0.96661201856456 GO:0016417 S-acyltransferase activity 1/789 29/18639 0.0344827586206897 0.8146060049823 0.715007014731113 0.980900248334246 GO:0099604 ligand-gated calcium channel activity 1/789 29/18639 0.0344827586206897 0.8146060049823 0.715007014731113 0.980900248334246 GO:0001786 phosphatidylserine binding 2/789 59/18639 0.0338983050847458 0.800799123541922 0.719306928841785 0.983725052216646 GO:0070888 E-box binding 2/789 59/18639 0.0338983050847458 0.800799123541922 0.719306928841785 0.983725052216646 GO:0001965 G-protein alpha-subunit binding 1/789 30/18639 0.0333333333333333 0.78745247148289 0.727089737212422 0.986262006548481 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/789 30/18639 0.0333333333333333 0.78745247148289 0.727089737212422 0.986262006548481 GO:0048019 receptor antagonist activity 1/789 30/18639 0.0333333333333333 0.78745247148289 0.727089737212422 0.986262006548481 GO:0051721 protein phosphatase 2A binding 1/789 30/18639 0.0333333333333333 0.78745247148289 0.727089737212422 0.986262006548481 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/789 60/18639 0.0333333333333333 0.78745247148289 0.727919640520804 0.986262006548481 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/789 60/18639 0.0333333333333333 0.78745247148289 0.727919640520804 0.986262006548481 GO:0015294 solute:monoatomic cation symporter activity 4/789 116/18639 0.0344827586206897 0.8146060049823 0.729025105068296 0.986262006548481 GO:0005525 GTP binding 14/789 378/18639 0.037037037037037 0.874947190536544 0.733361699368035 0.990602418530977 GO:0016836 hydro-lyase activity 2/789 61/18639 0.0327868852459016 0.774543414573334 0.736307315298128 0.991657792169885 GO:0005452 solute:inorganic anion antiporter activity 1/789 31/18639 0.032258064516129 0.762050778854409 0.738660815579846 0.991657792169885 GO:0070273 phosphatidylinositol-4-phosphate binding 1/789 31/18639 0.032258064516129 0.762050778854409 0.738660815579846 0.991657792169885 GO:0072349 modified amino acid transmembrane transporter activity 1/789 31/18639 0.032258064516129 0.762050778854409 0.738660815579846 0.991657792169885 GO:0015179 L-amino acid transmembrane transporter activity 2/789 62/18639 0.032258064516129 0.762050778854409 0.744473544565511 0.997935529967204 GO:0051059 NF-kappaB binding 1/789 32/18639 0.03125 0.738236692015209 0.749741889123887 0.999999419650112 GO:0120015 sterol transfer activity 1/789 32/18639 0.03125 0.738236692015209 0.749741889123887 0.999999419650112 GO:0015631 tubulin binding 14/789 385/18639 0.0363636363636364 0.859039059799516 0.757128262230823 0.999999419650112 GO:0004536 DNA nuclease activity 2/789 64/18639 0.03125 0.738236692015209 0.760156514504233 0.999999419650112 GO:0030296 protein tyrosine kinase activator activity 1/789 33/18639 0.0303030303030303 0.715865883166263 0.760353683044521 0.999999419650112 GO:0140097 catalytic activity, acting on DNA 12/789 336/18639 0.0357142857142857 0.84369907658881 0.766275573105278 0.999999419650112 GO:0042578 phosphoric ester hydrolase activity 13/789 363/18639 0.0358126721763085 0.84602331646922 0.769721030794717 0.999999419650112 GO:0008376 acetylgalactosaminyltransferase activity 1/789 34/18639 0.0294117647058824 0.694811004249609 0.770516047017319 0.999999419650112 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/789 34/18639 0.0294117647058824 0.694811004249609 0.770516047017319 0.999999419650112 GO:0051427 hormone receptor binding 1/789 34/18639 0.0294117647058824 0.694811004249609 0.770516047017319 0.999999419650112 GO:0004896 cytokine receptor activity 3/789 96/18639 0.03125 0.738236692015209 0.778141793591765 0.999999419650112 GO:0015291 secondary active transmembrane transporter activity 10/789 287/18639 0.0348432055749129 0.823121050330547 0.778142630528064 0.999999419650112 GO:0016853 isomerase activity 6/789 180/18639 0.0333333333333333 0.78745247148289 0.778638385858918 0.999999419650112 GO:0034061 DNA polymerase activity 1/789 35/18639 0.0285714285714286 0.674959261271048 0.780247992134402 0.999999419650112 GO:0042054 histone methyltransferase activity 2/789 67/18639 0.0298507462686567 0.705181317745871 0.782114866987238 0.999999419650112 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 6/789 181/18639 0.0331491712707182 0.7831019053421 0.783068199855278 0.999999419650112 GO:0005506 iron ion binding 5/789 154/18639 0.0324675324675325 0.766999160535282 0.785614458947654 0.999999419650112 GO:0005548 phospholipid transporter activity 2/789 68/18639 0.0294117647058824 0.694811004249609 0.789032431562721 0.999999419650112 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/789 36/18639 0.0277777777777778 0.656210392902408 0.789567726288668 0.999999419650112 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/789 36/18639 0.0277777777777778 0.656210392902408 0.789567726288668 0.999999419650112 GO:0005484 SNAP receptor activity 1/789 36/18639 0.0277777777777778 0.656210392902408 0.789567726288668 0.999999419650112 GO:0016409 palmitoyltransferase activity 1/789 36/18639 0.0277777777777778 0.656210392902408 0.789567726288668 0.999999419650112 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/789 36/18639 0.0277777777777778 0.656210392902408 0.789567726288668 0.999999419650112 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/789 36/18639 0.0277777777777778 0.656210392902408 0.789567726288668 0.999999419650112 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/789 36/18639 0.0277777777777778 0.656210392902408 0.789567726288668 0.999999419650112 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/789 36/18639 0.0277777777777778 0.656210392902408 0.789567726288668 0.999999419650112 GO:0016279 protein-lysine N-methyltransferase activity 2/789 69/18639 0.0289855072463768 0.684741279550339 0.795755716102737 0.999999419650112 GO:0098960 postsynaptic neurotransmitter receptor activity 2/789 69/18639 0.0289855072463768 0.684741279550339 0.795755716102737 0.999999419650112 GO:0030280 structural constituent of skin epidermis 1/789 37/18639 0.027027027027027 0.638474976878019 0.798492688066781 0.999999419650112 GO:0043394 proteoglycan binding 1/789 37/18639 0.027027027027027 0.638474976878019 0.798492688066781 0.999999419650112 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/789 70/18639 0.0285714285714286 0.674959261271048 0.802288748238125 0.999999419650112 GO:0016278 lysine N-methyltransferase activity 2/789 70/18639 0.0285714285714286 0.674959261271048 0.802288748238125 0.999999419650112 GO:0140658 ATP-dependent chromatin remodeler activity 5/789 158/18639 0.0316455696202532 0.747581460268566 0.803811218049866 0.999999419650112 GO:0043531 ADP binding 1/789 38/18639 0.0263157894736842 0.621673003802281 0.807039579213717 0.999999419650112 GO:0046943 carboxylic acid transmembrane transporter activity 6/789 188/18639 0.0319148936170213 0.753943855675107 0.812210378874705 0.999999419650112 GO:0005518 collagen binding 2/789 72/18639 0.0277777777777778 0.656210392902408 0.814800195721481 0.999999419650112 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/789 39/18639 0.0256410256410256 0.605732670371454 0.815224395728979 0.999999419650112 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/789 39/18639 0.0256410256410256 0.605732670371454 0.815224395728979 0.999999419650112 GO:0005342 organic acid transmembrane transporter activity 6/789 189/18639 0.0317460317460317 0.749954734745609 0.816111819692035 0.999999419650112 GO:0043177 organic acid binding 6/789 189/18639 0.0317460317460317 0.749954734745609 0.816111819692035 0.999999419650112 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/789 73/18639 0.0273972602739726 0.647221209437992 0.820786673345578 0.999999419650112 GO:0043539 protein serine/threonine kinase activator activity 2/789 73/18639 0.0273972602739726 0.647221209437992 0.820786673345578 0.999999419650112 GO:0071949 FAD binding 1/789 40/18639 0.025 0.590589353612167 0.823062457652088 0.999999419650112 GO:0140662 ATP-dependent protein folding chaperone 1/789 40/18639 0.025 0.590589353612167 0.823062457652088 0.999999419650112 GO:0051087 protein-folding chaperone binding 4/789 134/18639 0.0298507462686567 0.705181317745871 0.824079059920027 0.999999419650112 GO:0042287 MHC protein binding 1/789 41/18639 0.024390243902439 0.576184735231383 0.830568437592542 0.999999419650112 GO:0140318 protein transporter activity 1/789 41/18639 0.024390243902439 0.576184735231383 0.830568437592542 0.999999419650112 GO:0008017 microtubule binding 9/789 276/18639 0.0326086956521739 0.770333939494131 0.83083711348811 0.999999419650112 GO:0004520 DNA endonuclease activity 1/789 42/18639 0.0238095238095238 0.562466051059207 0.83775638805708 0.999999419650112 GO:0016859 cis-trans isomerase activity 1/789 42/18639 0.0238095238095238 0.562466051059207 0.83775638805708 0.999999419650112 GO:0048487 beta-tubulin binding 1/789 42/18639 0.0238095238095238 0.562466051059207 0.83775638805708 0.999999419650112 GO:0051879 Hsp90 protein binding 1/789 42/18639 0.0238095238095238 0.562466051059207 0.83775638805708 0.999999419650112 GO:0051540 metal cluster binding 2/789 77/18639 0.025974025974026 0.613599328428226 0.843030966655598 0.999999419650112 GO:0030295 protein kinase activator activity 4/789 139/18639 0.0287769784172662 0.679815083294581 0.844991293104781 0.999999419650112 GO:0017171 serine hydrolase activity 6/789 198/18639 0.0303030303030303 0.715865883166263 0.84840571891954 0.999999419650112 GO:0001046 core promoter sequence-specific DNA binding 1/789 44/18639 0.0227272727272727 0.536899412374698 0.851231466019402 0.999999419650112 GO:0019205 nucleobase-containing compound kinase activity 1/789 44/18639 0.0227272727272727 0.536899412374698 0.851231466019402 0.999999419650112 GO:0031267 small GTPase binding 9/789 283/18639 0.0318021201413428 0.751279743110884 0.851254063269801 0.999999419650112 GO:0042605 peptide antigen binding 1/789 45/18639 0.0222222222222222 0.524968314321926 0.857543828122693 0.999999419650112 GO:0046915 transition metal ion transmembrane transporter activity 1/789 45/18639 0.0222222222222222 0.524968314321926 0.857543828122693 0.999999419650112 GO:0043022 ribosome binding 3/789 112/18639 0.0267857142857143 0.632774307441608 0.858329089081775 0.999999419650112 GO:0046982 protein heterodimerization activity 12/789 369/18639 0.032520325203252 0.768246313641844 0.861080191781923 0.999999419650112 GO:0051020 GTPase binding 10/789 315/18639 0.0317460317460317 0.749954734745609 0.862837264717266 0.999999419650112 GO:0030276 clathrin binding 1/789 46/18639 0.0217391304347826 0.513555959662754 0.863588676977765 0.999999419650112 GO:0004721 phosphoprotein phosphatase activity 5/789 175/18639 0.0285714285714286 0.674959261271048 0.867833171400517 0.999999419650112 GO:0001784 phosphotyrosine residue binding 1/789 47/18639 0.0212765957446809 0.502629237116738 0.869377335820584 0.999999419650112 GO:0061749 forked DNA-dependent helicase activity 1/789 47/18639 0.0212765957446809 0.502629237116738 0.869377335820584 0.999999419650112 GO:0140359 ABC-type transporter activity 1/789 47/18639 0.0212765957446809 0.502629237116738 0.869377335820584 0.999999419650112 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/789 47/18639 0.0212765957446809 0.502629237116738 0.869377335820584 0.999999419650112 GO:0009378 four-way junction helicase activity 1/789 48/18639 0.0208333333333333 0.492157794676806 0.874920649183189 0.999999419650112 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/789 48/18639 0.0208333333333333 0.492157794676806 0.874920649183189 0.999999419650112 GO:0036121 double-stranded DNA helicase activity 1/789 48/18639 0.0208333333333333 0.492157794676806 0.874920649183189 0.999999419650112 GO:0043138 3'-5' DNA helicase activity 1/789 48/18639 0.0208333333333333 0.492157794676806 0.874920649183189 0.999999419650112 GO:0004527 exonuclease activity 2/789 84/18639 0.0238095238095238 0.562466051059207 0.876006879956484 0.999999419650112 GO:0051117 ATPase binding 2/789 84/18639 0.0238095238095238 0.562466051059207 0.876006879956484 0.999999419650112 GO:0008094 ATP-dependent activity, acting on DNA 6/789 210/18639 0.0285714285714286 0.674959261271048 0.884112961331444 0.999999419650112 GO:0000510 H3-H4 histone complex chaperone activity 4/789 151/18639 0.0264900662251656 0.625790043562561 0.886763986582813 0.999999419650112 GO:0140584 chromatin extrusion motor activity 4/789 151/18639 0.0264900662251656 0.625790043562561 0.886763986582813 0.999999419650112 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 4/789 151/18639 0.0264900662251656 0.625790043562561 0.886763986582813 0.999999419650112 GO:0140849 ATP-dependent H2AZ histone chaperone activity 4/789 151/18639 0.0264900662251656 0.625790043562561 0.886763986582813 0.999999419650112 GO:0008514 organic anion transmembrane transporter activity 8/789 269/18639 0.0297397769516729 0.70255982585834 0.887078009179751 0.999999419650112 GO:0015616 DNA translocase activity 4/789 152/18639 0.0263157894736842 0.621673003802281 0.889756592146357 0.999999419650112 GO:0140674 ATP-dependent histone chaperone activity 4/789 152/18639 0.0263157894736842 0.621673003802281 0.889756592146357 0.999999419650112 GO:0030544 Hsp70 protein binding 1/789 51/18639 0.0196078431372549 0.463207336166406 0.890180199695929 0.999999419650112 GO:0005096 GTPase activator activity 8/789 271/18639 0.029520295202952 0.697374882494072 0.891643909379291 0.999999419650112 GO:0061775 cohesin loader activity 4/789 153/18639 0.0261437908496732 0.617609781555208 0.892679820172092 0.999999419650112 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/789 122/18639 0.0245901639344262 0.580907560930001 0.894445438360303 0.999999419650112 GO:0030159 signaling receptor complex adaptor activity 1/789 52/18639 0.0192307692307692 0.45429950277859 0.894841692187855 0.999999419650112 GO:0004386 helicase activity 4/789 155/18639 0.0258064516129032 0.609640623083528 0.898323041137367 0.999999419650112 GO:0015276 ligand-gated monoatomic ion channel activity 5/789 186/18639 0.0268817204301075 0.635042315712008 0.899090843477935 0.999999419650112 GO:0008146 sulfotransferase activity 1/789 53/18639 0.0188679245283019 0.445727814046919 0.899305559668555 0.999999419650112 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/789 53/18639 0.0188679245283019 0.445727814046919 0.899305559668555 0.999999419650112 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/789 53/18639 0.0188679245283019 0.445727814046919 0.899305559668555 0.999999419650112 GO:0140375 immune receptor activity 4/789 156/18639 0.0256410256410256 0.605732670371454 0.90104546776261 0.999999419650112 GO:0031406 carboxylic acid binding 5/789 187/18639 0.0267379679144385 0.631646367499644 0.901586624988873 0.999999419650112 GO:0072341 modified amino acid binding 2/789 91/18639 0.021978021978022 0.51919943174696 0.902488580664453 0.999999419650112 GO:0140463 chromatin-protein adaptor activity 1/789 54/18639 0.0185185185185185 0.437473595268272 0.903580170312132 0.999999419650112 GO:0022834 ligand-gated channel activity 5/789 188/18639 0.0265957446808511 0.628286546395923 0.904028598926419 0.999999419650112 GO:0140597 protein carrier chaperone 5/789 188/18639 0.0265957446808511 0.628286546395923 0.904028598926419 0.999999419650112 GO:0052689 carboxylic ester hydrolase activity 2/789 92/18639 0.0217391304347826 0.513555959662754 0.90580977101933 0.999999419650112 GO:0008374 O-acyltransferase activity 1/789 55/18639 0.0181818181818182 0.429519529899758 0.907673538384433 0.999999419650112 GO:0003689 DNA clamp loader activity 4/789 160/18639 0.025 0.590589353612167 0.911301998140549 0.999999419650112 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/789 56/18639 0.0178571428571429 0.421849538294405 0.911593339192369 0.999999419650112 GO:0016410 N-acyltransferase activity 2/789 94/18639 0.0212765957446809 0.502629237116738 0.912137220580952 0.999999419650112 GO:0008276 protein methyltransferase activity 2/789 95/18639 0.0210526315789474 0.497338403041825 0.915149428767734 0.999999419650112 GO:0016798 hydrolase activity, acting on glycosyl bonds 3/789 130/18639 0.0230769230769231 0.545159403334308 0.917140048864876 0.999999419650112 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3/789 130/18639 0.0230769230769231 0.545159403334308 0.917140048864876 0.999999419650112 GO:0008236 serine-type peptidase activity 5/789 194/18639 0.0257731958762887 0.608855003723884 0.917599288169325 0.999999419650112 GO:0008408 3'-5' exonuclease activity 1/789 58/18639 0.0172413793103448 0.40730300249115 0.918941330755625 0.999999419650112 GO:0017116 single-stranded DNA helicase activity 1/789 58/18639 0.0172413793103448 0.40730300249115 0.918941330755625 0.999999419650112 GO:0031072 heat shock protein binding 3/789 131/18639 0.0229007633587786 0.540997881171451 0.919640680720407 0.999999419650112 GO:0140713 histone chaperone activity 4/789 164/18639 0.024390243902439 0.576184735231383 0.920601972907322 0.999999419650112 GO:0030594 neurotransmitter receptor activity 2/789 97/18639 0.0206185567010309 0.487084002979107 0.920885202888335 0.999999419650112 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 3/789 132/18639 0.0227272727272727 0.536899412374698 0.922072238456357 0.999999419650112 GO:0070063 RNA polymerase binding 1/789 59/18639 0.0169491525423729 0.400399561770961 0.922383303202416 0.999999419650112 GO:0008170 N-methyltransferase activity 2/789 98/18639 0.0204081632653061 0.482113758050749 0.923614333238831 0.999999419650112 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/789 60/18639 0.0166666666666667 0.393726235741445 0.925679297485155 0.999999419650112 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 6/789 229/18639 0.0262008733624454 0.618958274528036 0.926030590103979 0.999999419650112 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 4/789 167/18639 0.0239520958083832 0.56583411124519 0.926993347240192 0.999999419650112 GO:0043130 ubiquitin binding 2/789 100/18639 0.02 0.472471482889734 0.9288085153087 0.999999419650112 GO:0019905 syntaxin binding 1/789 61/18639 0.0163934426229508 0.387271707286667 0.928835497188272 0.999999419650112 GO:0005507 copper ion binding 1/789 63/18639 0.0158730158730159 0.374977367372805 0.934751950169598 0.999999419650112 GO:0022824 transmitter-gated monoatomic ion channel activity 1/789 63/18639 0.0158730158730159 0.374977367372805 0.934751950169598 0.999999419650112 GO:0022835 transmitter-gated channel activity 1/789 63/18639 0.0158730158730159 0.374977367372805 0.934751950169598 0.999999419650112 GO:0016757 glycosyltransferase activity 7/789 267/18639 0.0262172284644195 0.619344640492161 0.938322818596983 0.999999419650112 GO:0120013 lipid transfer activity 1/789 65/18639 0.0153846153846154 0.363439602222872 0.94017709425015 0.999999419650112 GO:0016887 ATP hydrolysis activity 12/789 417/18639 0.0287769784172662 0.679815083294581 0.94195623508929 0.999999419650112 GO:0000149 SNARE binding 2/789 106/18639 0.0188679245283019 0.445727814046919 0.942459554941401 0.999999419650112 GO:0004497 monooxygenase activity 2/789 106/18639 0.0188679245283019 0.445727814046919 0.942459554941401 0.999999419650112 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/789 67/18639 0.0149253731343284 0.352590658872936 0.945151680814487 0.999999419650112 GO:0003777 microtubule motor activity 1/789 68/18639 0.0147058823529412 0.347405502124804 0.947481818863021 0.999999419650112 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/789 68/18639 0.0147058823529412 0.347405502124804 0.947481818863021 0.999999419650112 GO:0030145 manganese ion binding 1/789 68/18639 0.0147058823529412 0.347405502124804 0.947481818863021 0.999999419650112 GO:0140223 general transcription initiation factor activity 1/789 68/18639 0.0147058823529412 0.347405502124804 0.947481818863021 0.999999419650112 GO:0008194 UDP-glycosyltransferase activity 3/789 145/18639 0.0206896551724138 0.48876360298938 0.948101115812492 0.999999419650112 GO:0002039 p53 binding 1/789 69/18639 0.0144927536231884 0.342370639775169 0.949713085080083 0.999999419650112 GO:0016782 transferase activity, transferring sulphur-containing groups 1/789 70/18639 0.0142857142857143 0.337479630635524 0.951849669671996 0.999999419650112 GO:0016741 transferase activity, transferring one-carbon groups 5/789 215/18639 0.0232558139534884 0.549385445220621 0.952693531496317 0.999999419650112 GO:0030246 carbohydrate binding 7/789 280/18639 0.025 0.590589353612167 0.954829949429316 0.999999419650112 GO:0004674 protein serine/threonine kinase activity 12/789 433/18639 0.0277136258660508 0.654694895459215 0.957778885679567 0.999999419650112 GO:0101005 deubiquitinase activity 2/789 115/18639 0.0173913043478261 0.410844767730203 0.958363531621098 0.999999419650112 GO:0003678 DNA helicase activity 1/789 74/18639 0.0135135135135135 0.319237488439009 0.959526943383209 0.999999419650112 GO:0035064 methylated histone binding 1/789 74/18639 0.0135135135135135 0.319237488439009 0.959526943383209 0.999999419650112 GO:0048029 monosaccharide binding 1/789 74/18639 0.0135135135135135 0.319237488439009 0.959526943383209 0.999999419650112 GO:0009055 electron transfer activity 2/789 116/18639 0.0172413793103448 0.40730300249115 0.959845116476836 0.999999419650112 GO:0003725 double-stranded RNA binding 1/789 75/18639 0.0133333333333333 0.314980988593156 0.96124702103851 0.999999419650112 GO:0044183 protein folding chaperone 1/789 75/18639 0.0133333333333333 0.314980988593156 0.96124702103851 0.999999419650112 GO:0051536 iron-sulfur cluster binding 1/789 76/18639 0.0131578947368421 0.310836501901141 0.962894085270389 0.999999419650112 GO:0140034 methylation-dependent protein binding 1/789 76/18639 0.0131578947368421 0.310836501901141 0.962894085270389 0.999999419650112 GO:0032182 ubiquitin-like protein binding 2/789 120/18639 0.0166666666666667 0.393726235741445 0.96528132252256 0.999999419650112 GO:0015108 chloride transmembrane transporter activity 2/789 121/18639 0.0165289256198347 0.390472299908871 0.96652561162401 0.999999419650112 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/789 122/18639 0.0163934426229508 0.387271707286667 0.967726947845072 0.999999419650112 GO:0016758 hexosyltransferase activity 4/789 197/18639 0.0203045685279188 0.4796664800911 0.969571543340022 0.999999419650112 GO:0033192 calmodulin-dependent protein phosphatase activity 1/789 81/18639 0.0123456790123457 0.291649063512181 0.970138074283358 0.999999419650112 GO:0140791 histone H2AXS140 phosphatase activity 1/789 81/18639 0.0123456790123457 0.291649063512181 0.970138074283358 0.999999419650112 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/789 81/18639 0.0123456790123457 0.291649063512181 0.970138074283358 0.999999419650112 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/789 81/18639 0.0123456790123457 0.291649063512181 0.970138074283358 0.999999419650112 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/789 81/18639 0.0123456790123457 0.291649063512181 0.970138074283358 0.999999419650112 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/789 81/18639 0.0123456790123457 0.291649063512181 0.970138074283358 0.999999419650112 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/789 81/18639 0.0123456790123457 0.291649063512181 0.970138074283358 0.999999419650112 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/789 81/18639 0.0123456790123457 0.291649063512181 0.970138074283358 0.999999419650112 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/789 82/18639 0.0121951219512195 0.288092367615691 0.971407664723623 0.999999419650112 GO:0033549 MAP kinase phosphatase activity 1/789 82/18639 0.0121951219512195 0.288092367615691 0.971407664723623 0.999999419650112 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/789 83/18639 0.0120481927710843 0.284621375234779 0.972623343579745 0.999999419650112 GO:0005254 chloride channel activity 1/789 83/18639 0.0120481927710843 0.284621375234779 0.972623343579745 0.999999419650112 GO:0015103 inorganic anion transmembrane transporter activity 3/789 165/18639 0.0181818181818182 0.429519529899758 0.972851405276194 0.999999419650112 GO:0019783 ubiquitin-like protein peptidase activity 2/789 127/18639 0.015748031496063 0.372024789676956 0.97313693223923 0.999999419650112 GO:0017018 myosin phosphatase activity 1/789 84/18639 0.0119047619047619 0.281233025529603 0.973787397358339 0.999999419650112 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/789 128/18639 0.015625 0.369118346007605 0.974108551145973 0.999999419650112 GO:0022804 active transmembrane transporter activity 12/789 457/18639 0.0262582056892779 0.620312669001839 0.974408412630449 0.999999419650112 GO:0008168 methyltransferase activity 4/789 204/18639 0.0196078431372549 0.463207336166406 0.975399102872024 0.999999419650112 GO:0050660 flavin adenine dinucleotide binding 1/789 86/18639 0.0116279069767442 0.27469272261031 0.975969295518953 0.999999419650112 GO:0016791 phosphatase activity 6/789 273/18639 0.021978021978022 0.51919943174696 0.976217636515706 0.999999419650112 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 5/789 243/18639 0.0205761316872428 0.486081772520302 0.978426288691754 0.999999419650112 GO:0004676 3-phosphoinositide-dependent protein kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:0004711 ribosomal protein S6 kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:0035175 histone H3S10 kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:0035979 histone H2AXS139 kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:0044022 histone H3S28 kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:0044023 histone H4S1 kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:0044024 histone H2AS1 kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:0044025 histone H2BS14 kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:0072354 histone H3T3 kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:0072371 histone H2AS121 kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:0072518 Rho-dependent protein serine/threonine kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:0140823 histone H2BS36 kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:0140855 histone H3S57 kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:0140995 histone H2A kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:0140997 histone H4 kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:0140998 histone H2B kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:1990244 histone H2AT120 kinase activity 5/789 245/18639 0.0204081632653061 0.482113758050749 0.979638667782936 0.999999419650112 GO:0004677 DNA-dependent protein kinase activity 5/789 246/18639 0.0203252032520325 0.480153946026152 0.980220680417785 0.999999419650112 GO:0140857 histone H3T45 kinase activity 5/789 246/18639 0.0203252032520325 0.480153946026152 0.980220680417785 0.999999419650112 GO:0035402 histone H3T11 kinase activity 5/789 247/18639 0.0202429149797571 0.478210002924832 0.980787094805539 0.999999419650112 GO:0035403 histone H3T6 kinase activity 5/789 247/18639 0.0202429149797571 0.478210002924832 0.980787094805539 0.999999419650112 GO:0004252 serine-type endopeptidase activity 3/789 176/18639 0.0170454545454545 0.402674559281023 0.981180217453023 0.999999419650112 GO:0004679 AMP-activated protein kinase activity 5/789 248/18639 0.0201612903225806 0.476281736784006 0.981338290767746 0.999999419650112 GO:0140767 enzyme-substrate adaptor activity 2/789 139/18639 0.0143884892086331 0.339907541647291 0.982785843064545 0.999999419650112 GO:0045182 translation regulator activity 8/789 356/18639 0.0224719101123595 0.530866834707566 0.985099563997209 0.999999419650112 GO:0042626 ATPase-coupled transmembrane transporter activity 1/789 98/18639 0.0102040816326531 0.241056879025374 0.985736789460836 0.999999419650112 GO:0008509 monoatomic anion transmembrane transporter activity 2/789 149/18639 0.0134228187919463 0.317094954959553 0.988173260335743 0.999999419650112 GO:0004722 protein serine/threonine phosphatase activity 1/789 103/18639 0.00970873786407767 0.229355088781424 0.988524343052015 0.999999419650112 GO:0005253 monoatomic anion channel activity 1/789 103/18639 0.00970873786407767 0.229355088781424 0.988524343052015 0.999999419650112 GO:0004843 cysteine-type deubiquitinase activity 1/789 108/18639 0.00925925925925926 0.218736797634136 0.99076766017991 0.999999419650112 GO:0015399 primary active transmembrane transporter activity 2/789 166/18639 0.0120481927710843 0.284621375234779 0.993802918974235 0.999999419650112 GO:0004518 nuclease activity 3/789 209/18639 0.0143540669856459 0.339094365710335 0.993946604971312 0.999999419650112 GO:0022853 active monoatomic ion transmembrane transporter activity 1/789 118/18639 0.00847457627118644 0.20019978088548 0.994025493284614 0.999999419650112 GO:0106310 protein serine kinase activity 7/789 361/18639 0.0193905817174515 0.458074844906944 0.994727496243597 0.999999419650112 GO:0140030 modification-dependent protein binding 2/789 173/18639 0.0115606936416185 0.27310490340447 0.995263458372663 0.999999419650112 GO:0003823 antigen binding 2/789 174/18639 0.0114942528735632 0.2715353349941 0.995442405155118 0.999999419650112 GO:0004519 endonuclease activity 1/789 127/18639 0.0078740157480315 0.186012394838478 0.995962578434185 0.999999419650112 GO:0015078 proton transmembrane transporter activity 2/789 185/18639 0.0108108108108108 0.255389990751207 0.997021707514464 0.999999419650112 GO:0016779 nucleotidyltransferase activity 1/789 136/18639 0.00735294117647059 0.173702751062402 0.997272143308544 0.999999419650112 GO:0004175 endopeptidase activity 7/789 405/18639 0.0172839506172839 0.408308688917054 0.998543758464697 0.999999419650112 GO:0016755 aminoacyltransferase activity 9/789 496/18639 0.0181451612903226 0.428653563105605 0.999179368773625 0.999999419650112 GO:0016874 ligase activity 1/789 167/18639 0.00598802395209581 0.141458527811298 0.99929426101648 0.999999419650112 GO:0061630 ubiquitin protein ligase activity 5/789 353/18639 0.0141643059490085 0.334611531791596 0.999311804997547 0.999999419650112 GO:0019787 ubiquitin-like protein transferase activity 8/789 479/18639 0.0167014613778706 0.394548211181406 0.99953020860534 0.999999419650112 GO:0004842 ubiquitin-protein transferase activity 7/789 449/18639 0.0155902004454343 0.368296256150127 0.999623340674642 0.999999419650112 GO:0061659 ubiquitin-like protein ligase activity 5/789 372/18639 0.0134408602150538 0.317521157856004 0.999636524701049 0.999999419650112 GO:0008234 cysteine-type peptidase activity 1/789 187/18639 0.0053475935828877 0.126329273499929 0.999705364422479 0.999999419650112 GO:0140098 catalytic activity, acting on RNA 4/789 387/18639 0.0103359173126615 0.244171308986943 0.999952786032568 0.999999419650112 GO:0030371 translation repressor activity 1/789 329/18639 0.00303951367781155 0.0718041767309626 0.999999419650112 0.999999419650112