ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	131/2246	175/18639	0.748571428571429	6.21220964253912	3.34672287159713e-83	4.04284122888933e-80
GO:0045296	cadherin binding	105/2246	334/18639	0.31437125748503	2.60888952282434	2.46169109368143e-21	1.48686142058358e-18
GO:0009055	electron transfer activity	55/2246	116/18639	0.474137931034483	3.93475373844689	4.57053820854808e-21	1.84040338530869e-18
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	40/2246	68/18639	0.588235294117647	4.88161961133518	4.07237570568232e-20	1.22985746311606e-17
GO:0008137	NADH dehydrogenase (ubiquinone) activity	26/2246	41/18639	0.634146341463415	5.26262406880525	1.14415486650239e-14	2.76427815746978e-12
GO:0022853	active monoatomic ion transmembrane transporter activity	46/2246	118/18639	0.389830508474576	3.23510723395264	6.99534113207952e-14	1.40839534792534e-11
GO:0003954	NADH dehydrogenase activity	26/2246	44/18639	0.590909090909091	4.90380879138671	1.28894731813923e-13	2.22435480044598e-11
GO:0019843	rRNA binding	31/2246	65/18639	0.476923076923077	3.95786697719022	1.43164535377748e-12	2.161784484204e-10
GO:0004601	peroxidase activity	28/2246	57/18639	0.491228070175439	4.07658058771149	6.96903219462842e-12	9.35398987901238e-10
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	28/2246	58/18639	0.482758620689655	4.00629471550956	1.19286469999137e-11	1.44098055758958e-09
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	28/2246	59/18639	0.474576271186441	3.93839141524669	2.01002657179857e-11	2.20737463521152e-09
GO:0016853	isomerase activity	55/2246	180/18639	0.305555555555556	2.53573018699911	2.7722008693902e-11	2.79068220851947e-09
GO:0043021	ribonucleoprotein complex binding	54/2246	177/18639	0.305084745762712	2.53182305265859	4.47219956673356e-11	4.15570544354934e-09
GO:0051082	unfolded protein binding	42/2246	121/18639	0.347107438016529	2.88055901032506	7.0385790405986e-11	6.07328820074508e-09
GO:0015399	primary active transmembrane transporter activity	50/2246	166/18639	0.301204819277108	2.49962449978006	3.82513366905811e-10	3.08050764814813e-08
GO:0048027	mRNA 5'-UTR binding	16/2246	24/18639	0.666666666666667	5.53250222617988	5.3343561325569e-10	4.02743888008046e-08
GO:0008135	translation factor activity, RNA binding	32/2246	83/18639	0.385542168674699	3.19951935971848	6.06372978114216e-10	4.30881504448219e-08
GO:0003743	translation initiation factor activity	24/2246	51/18639	0.470588235294118	3.90529568906815	6.82074501047397e-10	4.57747776258475e-08
GO:0180051	translation factor activity	32/2246	84/18639	0.380952380952381	3.16142984353136	8.67052411564505e-10	5.51262796405222e-08
GO:0016209	antioxidant activity	32/2246	86/18639	0.372093023255814	3.08790821926319	1.73529822468699e-09	1.0453504599075e-07
GO:0016860	intramolecular oxidoreductase activity	24/2246	53/18639	0.452830188679245	3.75792604042407	1.81724831606436e-09	1.0453504599075e-07
GO:0003779	actin binding	93/2246	443/18639	0.209932279909707	1.7421762089212	4.69917762126507e-08	2.47414055751343e-06
GO:0031720	haptoglobin binding	9/2246	10/18639	0.9	7.46887800534283	4.71069808135835e-08	2.47414055751343e-06
GO:0043022	ribosome binding	35/2246	112/18639	0.3125	2.59336041852182	5.72495601069527e-08	2.86066118389918e-06
GO:0015078	proton transmembrane transporter activity	49/2246	185/18639	0.264864864864865	2.19804818175255	5.92024251634765e-08	2.86066118389918e-06
GO:0140104	molecular carrier activity	60/2246	249/18639	0.240963855421687	1.99969959982405	8.69922455723255e-08	4.0417935635142e-06
GO:0016887	ATP hydrolysis activity	87/2246	417/18639	0.20863309352518	1.73139458157428	1.69074199487364e-07	7.56450492521245e-06
GO:0005344	oxygen carrier activity	10/2246	14/18639	0.714285714285714	5.9276809566213	4.0016448407421e-07	1.72642391700588e-05
GO:0051015	actin filament binding	51/2246	209/18639	0.244019138755981	2.02505464259694	5.22922682340054e-07	2.17824344919581e-05
GO:0008017	microtubule binding	62/2246	276/18639	0.22463768115942	1.86421270664757	7.494570935531e-07	3.01781389670715e-05
GO:0016651	oxidoreductase activity, acting on NAD(P)H	28/2246	88/18639	0.318181818181818	2.6405124261313	7.85121057296331e-07	3.05943947488377e-05
GO:0055105	ubiquitin-protein transferase inhibitor activity	10/2246	15/18639	0.666666666666667	5.53250222617988	1.07002321940042e-06	4.03933765323658e-05
GO:0015036	disulfide oxidoreductase activity	17/2246	40/18639	0.425	3.52697016918967	1.28443072333723e-06	4.70179489027689e-05
GO:0000287	magnesium ion binding	53/2246	230/18639	0.230434782608696	1.91232142165783	2.08068860096888e-06	7.39256420579531e-05
GO:0015631	tubulin binding	78/2246	385/18639	0.202597402597403	1.68130587133259	2.38509126324235e-06	8.23197213141932e-05
GO:0048029	monosaccharide binding	24/2246	74/18639	0.324324324324324	2.69148756949291	3.24183365281373e-06	0.000108781529238861
GO:1990948	ubiquitin ligase inhibitor activity	8/2246	11/18639	0.727272727272727	6.03545697401441	5.17275702431604e-06	0.000168883526631724
GO:0140662	ATP-dependent protein folding chaperone	16/2246	40/18639	0.4	3.31950133570793	6.822883634765e-06	0.000216895879757793
GO:0019838	growth factor binding	35/2246	136/18639	0.257352941176471	2.13570857995914	8.79988904319263e-06	0.000272570922158377
GO:0003697	single-stranded DNA binding	32/2246	121/18639	0.264462809917355	2.19471162691433	1.15033702558916e-05	0.000347401781727925
GO:0004129	cytochrome-c oxidase activity	9/2246	15/18639	0.6	4.97925200356189	1.33382898203457e-05	0.000383634621499468
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	9/2246	15/18639	0.6	4.97925200356189	1.33382898203457e-05	0.000383634621499468
GO:0015035	protein-disulfide reductase activity	14/2246	34/18639	0.411764705882353	3.41713372793463	1.72789831914838e-05	0.000485418876635173
GO:0016675	oxidoreductase activity, acting on a heme group of donors	9/2246	16/18639	0.5625	4.66804875333927	2.72171616532129e-05	0.000747234801751845
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	18/2246	54/18639	0.333333333333333	2.76625111308994	3.54548229535578e-05	0.00091924150454298
GO:0055106	ubiquitin-protein transferase regulator activity	14/2246	36/18639	0.388888888888889	3.22729296527159	3.72871140087798e-05	0.00091924150454298
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	14/2246	36/18639	0.388888888888889	3.22729296527159	3.72871140087798e-05	0.00091924150454298
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	14/2246	36/18639	0.388888888888889	3.22729296527159	3.72871140087798e-05	0.00091924150454298
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	14/2246	36/18639	0.388888888888889	3.22729296527159	3.72871140087798e-05	0.00091924150454298
GO:0030515	snoRNA binding	13/2246	32/18639	0.40625	3.37136854407836	4.09747578070127e-05	0.000989950148617427
GO:0044183	protein folding chaperone	22/2246	75/18639	0.293333333333333	2.43430097951914	4.79787444462642e-05	0.00113643771158995
GO:0031625	ubiquitin protein ligase binding	60/2246	302/18639	0.198675496688742	1.64875894157678	6.02726717534906e-05	0.00140018052842724
GO:0016859	cis-trans isomerase activity	15/2246	42/18639	0.357142857142857	2.96384047831065	6.36798753167325e-05	0.00143523394645303
GO:0044389	ubiquitin-like protein ligase binding	63/2246	322/18639	0.195652173913043	1.62366913159627	6.41578088646221e-05	0.00143523394645303
GO:0048407	platelet-derived growth factor binding	7/2246	11/18639	0.636363636363636	5.28102485226261	7.75205855674168e-05	0.0017026339520989
GO:0098641	cadherin binding involved in cell-cell adhesion	9/2246	18/18639	0.5	4.14937666963491	9.22320348207388e-05	0.00198957675113308
GO:0017116	single-stranded DNA helicase activity	18/2246	58/18639	0.310344827586207	2.57547517425615	0.000102499648761737	0.00213650780068457
GO:0000217	DNA secondary structure binding	14/2246	39/18639	0.358974358974359	2.9790396602507	0.00010434930483476	0.00213650780068457
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	14/2246	39/18639	0.358974358974359	2.9790396602507	0.00010434930483476	0.00213650780068457
GO:0003678	DNA helicase activity	21/2246	74/18639	0.283783783783784	2.3550516233063	0.000119726620554861	0.00237097963328314
GO:0003684	damaged DNA binding	21/2246	74/18639	0.283783783783784	2.3550516233063	0.000119726620554861	0.00237097963328314
GO:0003756	protein disulfide isomerase activity	9/2246	19/18639	0.473684210526316	3.93098842386465	0.000156519077482097	0.00300119119997417
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	9/2246	19/18639	0.473684210526316	3.93098842386465	0.000156519077482097	0.00300119119997417
GO:0004602	glutathione peroxidase activity	10/2246	23/18639	0.434782608695652	3.60815362576948	0.000163169518961577	0.00307982467039976
GO:0098631	cell adhesion mediator activity	21/2246	76/18639	0.276315789473684	2.29307658058771	0.000181116407391846	0.0033598675300356
GO:0005201	extracellular matrix structural constituent	37/2246	168/18639	0.220238095238095	1.82770162829157	0.000183568921343005	0.0033598675300356
GO:0140097	catalytic activity, acting on DNA	63/2246	336/18639	0.1875	1.55601625111309	0.000225484168120556	0.00406544589686017
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	30/2246	128/18639	0.234375	1.94502031389136	0.000232871814102703	0.00413689928582449
GO:0051087	protein-folding chaperone binding	31/2246	134/18639	0.23134328358209	1.91986084714451	0.000236995749832615	0.0041491429825768
GO:0031491	nucleosome binding	20/2246	74/18639	0.27027027027027	2.24290630791076	0.000352430904264864	0.0060819504621708
GO:0070182	DNA polymerase binding	9/2246	21/18639	0.428571428571429	3.55660857397278	0.000397490595133799	0.00676293857636097
GO:0035925	mRNA 3'-UTR AU-rich region binding	11/2246	30/18639	0.366666666666667	3.04287622439893	0.000463160390592622	0.00777080210883177
GO:0140517	protein-RNA adaptor activity	9/2246	22/18639	0.409090909090909	3.39494454788311	0.000601120127650172	0.00994730293426586
GO:0051540	metal cluster binding	20/2246	77/18639	0.25974025974026	2.15552034786229	0.000617692676214196	0.00996797665275478
GO:0008094	ATP-dependent activity, acting on DNA	42/2246	210/18639	0.2	1.65975066785396	0.00062410979026327	0.00996797665275478
GO:0000400	four-way junction DNA binding	8/2246	18/18639	0.444444444444444	3.68833481745325	0.000627124358948149	0.00996797665275478
GO:0050786	RAGE receptor binding	6/2246	11/18639	0.545454545454545	4.52659273051081	0.000818588436812964	0.0126768960522645
GO:0070990	snRNP binding	6/2246	11/18639	0.545454545454545	4.52659273051081	0.000818588436812964	0.0126768960522645
GO:0016829	lyase activity	40/2246	200/18639	0.2	1.65975066785396	0.000829035420636502	0.0126768960522645
GO:0031492	nucleosomal DNA binding	13/2246	42/18639	0.30952380952381	2.56866174786923	0.000944407459864651	0.0138434771296749
GO:0004857	enzyme inhibitor activity	72/2246	416/18639	0.173076923076923	1.43632269333516	0.000945158807778719	0.0138434771296749
GO:0008301	DNA binding, bending	8/2246	19/18639	0.421052631578947	3.49421193232413	0.000969382745468912	0.0138434771296749
GO:0005507	copper ion binding	17/2246	63/18639	0.26984126984127	2.23934613916804	0.000970843151476177	0.0138434771296749
GO:0031386	protein tag activity	7/2246	15/18639	0.466666666666667	3.87275155832591	0.000974085725184077	0.0138434771296749
GO:0141047	molecular tag activity	7/2246	15/18639	0.466666666666667	3.87275155832591	0.000974085725184077	0.0138434771296749
GO:0016866	intramolecular transferase activity	10/2246	28/18639	0.357142857142857	2.96384047831065	0.00106105430530729	0.0147328000093242
GO:0051537	2 iron, 2 sulfur cluster binding	10/2246	28/18639	0.357142857142857	2.96384047831065	0.00106105430530729	0.0147328000093242
GO:0043531	ADP binding	12/2246	38/18639	0.315789473684211	2.6206589492431	0.00120849648653108	0.0165893608605629
GO:0051536	iron-sulfur cluster binding	19/2246	76/18639	0.25	2.07468833481745	0.00137329130384513	0.0186397291578081
GO:0022804	active transmembrane transporter activity	77/2246	457/18639	0.168490153172867	1.39825822127741	0.00140335249915635	0.0188361090997874
GO:0043236	laminin binding	10/2246	29/18639	0.344827586206897	2.86163908250683	0.00144640356565514	0.019200609970455
GO:0019825	oxygen binding	11/2246	34/18639	0.323529411764706	2.68489078623435	0.00153705812122555	0.0201822414178312
GO:0005200	structural constituent of cytoskeleton	25/2246	112/18639	0.223214285714286	1.85240029894415	0.00156182133931842	0.0202868836332973
GO:0003712	transcription coregulator activity	82/2246	495/18639	0.165656565656566	1.37474297741439	0.00165207503937255	0.021111616932158
GO:0140297	DNA-binding transcription factor binding	81/2246	488/18639	0.165983606557377	1.37745700918208	0.00166026788787666	0.021111616932158
GO:0098632	cell-cell adhesion mediator activity	15/2246	55/18639	0.272727272727273	2.2632963652554	0.00168389529436495	0.0211890157874256
GO:0001968	fibronectin binding	10/2246	30/18639	0.333333333333333	2.76625111308994	0.0019380251531864	0.0241354060314347
GO:0019212	phosphatase inhibitor activity	15/2246	56/18639	0.267857142857143	2.22288035873299	0.00204793509990396	0.025243934700857
GO:0003777	microtubule motor activity	17/2246	68/18639	0.25	2.07468833481745	0.00240056392158725	0.0292917294674485
GO:0003774	cytoskeletal motor activity	31/2246	153/18639	0.202614379084967	1.68144675501545	0.002439754949675	0.029472239792074
GO:0000049	tRNA binding	19/2246	80/18639	0.2375	1.97095391807658	0.00260097746109216	0.0311087205247458
GO:0005178	integrin binding	32/2246	161/18639	0.198757763975155	1.64944165749462	0.00288044109298502	0.0341134592188814
GO:0019208	phosphatase regulator activity	25/2246	117/18639	0.213675213675214	1.77323789300637	0.0029364840778449	0.0344395414178315
GO:0004386	helicase activity	31/2246	155/18639	0.2	1.65975066785396	0.0030051678906453	0.0347656886021724
GO:0001618	virus receptor activity	19/2246	81/18639	0.234567901234568	1.94662115365588	0.00302185207220869	0.0347656886021724
GO:0140597	protein carrier chaperone	36/2246	188/18639	0.191489361702128	1.58912297986018	0.00317809507961931	0.036218291096039
GO:0008320	protein transmembrane transporter activity	9/2246	27/18639	0.333333333333333	2.76625111308994	0.00323652794031498	0.0365394930084159
GO:0019842	vitamin binding	30/2246	150/18639	0.2	1.65975066785396	0.00347217066740031	0.0387672741538902
GO:0140272	exogenous protein binding	19/2246	82/18639	0.231707317073171	1.92288187129423	0.00349804046587254	0.0387672741538902
GO:0001094	TFIID-class transcription factor complex binding	5/2246	10/18639	0.5	4.14937666963491	0.00377456262355071	0.0395096529123434
GO:0005528	FK506 binding	5/2246	10/18639	0.5	4.14937666963491	0.00377456262355071	0.0395096529123434
GO:0032356	oxidized DNA binding	5/2246	10/18639	0.5	4.14937666963491	0.00377456262355071	0.0395096529123434
GO:0047429	nucleoside triphosphate diphosphatase activity	5/2246	10/18639	0.5	4.14937666963491	0.00377456262355071	0.0395096529123434
GO:0050815	phosphoserine residue binding	5/2246	10/18639	0.5	4.14937666963491	0.00377456262355071	0.0395096529123434
GO:0097177	mitochondrial ribosome binding	5/2246	10/18639	0.5	4.14937666963491	0.00377456262355071	0.0395096529123434
GO:0016530	metallochaperone activity	6/2246	14/18639	0.428571428571429	3.55660857397278	0.00385938662554348	0.0395096529123434
GO:0032036	myosin heavy chain binding	6/2246	14/18639	0.428571428571429	3.55660857397278	0.00385938662554348	0.0395096529123434
GO:0044548	S100 protein binding	6/2246	14/18639	0.428571428571429	3.55660857397278	0.00385938662554348	0.0395096529123434
GO:0017069	snRNA binding	14/2246	54/18639	0.259259259259259	2.1515286435144	0.0039434093509926	0.0396969874666588
GO:0051287	NAD binding	14/2246	54/18639	0.259259259259259	2.1515286435144	0.0039434093509926	0.0396969874666588
GO:0003727	single-stranded RNA binding	20/2246	89/18639	0.224719101123595	1.86488839084715	0.0040430904954489	0.0403640770124154
GO:0004860	protein kinase inhibitor activity	19/2246	84/18639	0.226190476190476	1.87709896959674	0.00463823447555484	0.0459261249710676
GO:0008574	plus-end-directed microtubule motor activity	7/2246	19/18639	0.368421052631579	3.05743544078362	0.00493434704767525	0.0484609043381439
GO:0050840	extracellular matrix binding	16/2246	67/18639	0.238805970149254	1.98179184221369	0.00516407245136106	0.0503080606551948
GO:0016835	carbon-oxygen lyase activity	18/2246	79/18639	0.227848101265823	1.89085519122603	0.00531800359595596	0.0513931867513184
GO:0000774	adenyl-nucleotide exchange factor activity	6/2246	15/18639	0.4	3.31950133570793	0.00578292055911642	0.0554426034556559
GO:0003713	transcription coactivator activity	45/2246	256/18639	0.17578125	1.45876523541852	0.0058444633649553	0.055591431061937
GO:0004523	RNA-DNA hybrid ribonuclease activity	5/2246	11/18639	0.454545454545455	3.77216060875901	0.00623787444583217	0.0570860025042823
GO:0005536	D-glucose binding	5/2246	11/18639	0.454545454545455	3.77216060875901	0.00623787444583217	0.0570860025042823
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	5/2246	11/18639	0.454545454545455	3.77216060875901	0.00623787444583217	0.0570860025042823
GO:0034511	U3 snoRNA binding	5/2246	11/18639	0.454545454545455	3.77216060875901	0.00623787444583217	0.0570860025042823
GO:0045294	alpha-catenin binding	5/2246	11/18639	0.454545454545455	3.77216060875901	0.00623787444583217	0.0570860025042823
GO:0016504	peptidase activator activity	14/2246	57/18639	0.245614035087719	2.03829029385574	0.00662267017255904	0.0601517711913634
GO:0016004	phospholipase activator activity	7/2246	20/18639	0.35	2.90456366874443	0.00681260269355268	0.0614151048791913
GO:0008187	poly-pyrimidine tract binding	9/2246	30/18639	0.3	2.48962600178094	0.00707840464909883	0.0633386134526769
GO:0003688	DNA replication origin binding	6/2246	16/18639	0.375	3.11203250222618	0.00832119214156319	0.0726468226301858
GO:0017070	U6 snRNA binding	6/2246	16/18639	0.375	3.11203250222618	0.00832119214156319	0.0726468226301858
GO:0043023	ribosomal large subunit binding	6/2246	16/18639	0.375	3.11203250222618	0.00832119214156319	0.0726468226301858
GO:0061749	forked DNA-dependent helicase activity	12/2246	47/18639	0.25531914893617	2.11883063981357	0.00835919565032767	0.0726468226301858
GO:0004864	protein phosphatase inhibitor activity	13/2246	53/18639	0.245283018867925	2.03554327189637	0.00881895431121843	0.0760949771996561
GO:0003689	DNA clamp loader activity	30/2246	160/18639	0.1875	1.55601625111309	0.0089943538940895	0.077058010667093
GO:0008307	structural constituent of muscle	11/2246	42/18639	0.261904761904762	2.17348301742781	0.00930080532500063	0.0791223438915547
GO:0005506	iron ion binding	29/2246	154/18639	0.188311688311688	1.56275225220016	0.0095110795719186	0.0797868345333503
GO:0005527	macrolide binding	5/2246	12/18639	0.416666666666667	3.45781389136242	0.00964311079624929	0.0797868345333503
GO:0016840	carbon-nitrogen lyase activity	5/2246	12/18639	0.416666666666667	3.45781389136242	0.00964311079624929	0.0797868345333503
GO:0097371	MDM2/MDM4 family protein binding	5/2246	12/18639	0.416666666666667	3.45781389136242	0.00964311079624929	0.0797868345333503
GO:0009378	four-way junction helicase activity	12/2246	48/18639	0.25	2.07468833481745	0.00995188520795668	0.0811220796416132
GO:0036121	double-stranded DNA helicase activity	12/2246	48/18639	0.25	2.07468833481745	0.00995188520795668	0.0811220796416132
GO:0019210	kinase inhibitor activity	19/2246	90/18639	0.211111111111111	1.75195903829029	0.0100059518763248	0.0811220796416132
GO:0004527	exonuclease activity	18/2246	84/18639	0.214285714285714	1.77830428698639	0.0102653290967176	0.0826701169922323
GO:0020037	heme binding	27/2246	142/18639	0.190140845070423	1.57793197295975	0.0106153252359009	0.0849226018872068
GO:0022884	macromolecule transmembrane transporter activity	9/2246	32/18639	0.28125	2.33402437666963	0.0111223288454167	0.0878155114069502
GO:0031369	translation initiation factor binding	9/2246	32/18639	0.28125	2.33402437666963	0.0111223288454167	0.0878155114069502
GO:0044325	transmembrane transporter binding	26/2246	136/18639	0.191176470588235	1.58652637368393	0.0112021033308997	0.0878710443099141
GO:0032977	membrane insertase activity	6/2246	17/18639	0.352941176470588	2.92897176680111	0.0115691409310054	0.0895866810554776
GO:0051787	misfolded protein binding	6/2246	17/18639	0.352941176470588	2.92897176680111	0.0115691409310054	0.0895866810554776
GO:0060590	ATPase regulator activity	12/2246	49/18639	0.244897959183673	2.03234775655587	0.0117697917342453	0.0905599262099895
GO:0003714	transcription corepressor activity	36/2246	204/18639	0.176470588235294	1.46448588340056	0.0119112926705262	0.0910686173797196
GO:0031072	heat shock protein binding	25/2246	131/18639	0.190839694656489	1.58373155329577	0.0129729516841727	0.0985617964432745
GO:0042393	histone binding	42/2246	247/18639	0.17004048582996	1.41112404959244	0.0131763463496784	0.0994814149400721
GO:0030020	extracellular matrix structural constituent conferring tensile strength	11/2246	44/18639	0.25	2.07468833481745	0.0133105771578193	0.0998706658797869
GO:0048306	calcium-dependent protein binding	17/2246	80/18639	0.2125	1.76348508459484	0.0134456468194829	0.100261366407008
GO:0019104	DNA N-glycosylase activity	5/2246	13/18639	0.384615384615385	3.19182820741147	0.0141364432844064	0.102872430647969
GO:0031994	insulin-like growth factor I binding	5/2246	13/18639	0.384615384615385	3.19182820741147	0.0141364432844064	0.102872430647969
GO:0043560	insulin receptor substrate binding	5/2246	13/18639	0.384615384615385	3.19182820741147	0.0141364432844064	0.102872430647969
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	5/2246	13/18639	0.384615384615385	3.19182820741147	0.0141364432844064	0.102872430647969
GO:0046906	tetrapyrrole binding	28/2246	152/18639	0.184210526315789	1.52871772039181	0.0142567044011612	0.10312634081798
GO:0097718	disordered domain specific binding	8/2246	28/18639	0.285714285714286	2.37107238264852	0.0148221912847364	0.106578613523581
GO:0017134	fibroblast growth factor binding	7/2246	23/18639	0.304347826086957	2.52570753803864	0.0155973260047417	0.109681666561586
GO:0003746	translation elongation factor activity	6/2246	18/18639	0.333333333333333	2.76625111308994	0.0156169260336033	0.109681666561586
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	6/2246	18/18639	0.333333333333333	2.76625111308994	0.0156169260336033	0.109681666561586
GO:0070628	proteasome binding	6/2246	18/18639	0.333333333333333	2.76625111308994	0.0156169260336033	0.109681666561586
GO:0019888	protein phosphatase regulator activity	21/2246	107/18639	0.196261682242991	1.62872729088473	0.0159627622441546	0.111462524803115
GO:0030246	carbohydrate binding	46/2246	280/18639	0.164285714285714	1.3633666200229	0.0177383895544517	0.123149279205619
GO:0004532	RNA exonuclease activity	10/2246	40/18639	0.25	2.07468833481745	0.0178568701592505	0.123263423727855
GO:0001091	RNA polymerase II general transcription initiation factor binding	7/2246	24/18639	0.291666666666667	2.4204697239537	0.019783115277419	0.133188168893579
GO:0005540	hyaluronic acid binding	7/2246	24/18639	0.291666666666667	2.4204697239537	0.019783115277419	0.133188168893579
GO:0060229	lipase activator activity	7/2246	24/18639	0.291666666666667	2.4204697239537	0.019783115277419	0.133188168893579
GO:0070742	C2H2 zinc finger domain binding	5/2246	14/18639	0.357142857142857	2.96384047831065	0.0198459192059968	0.133188168893579
GO:1990825	sequence-specific mRNA binding	5/2246	14/18639	0.357142857142857	2.96384047831065	0.0198459192059968	0.133188168893579
GO:0140789	histone phosphatase activity	25/2246	136/18639	0.183823529411765	1.52550612854225	0.0202267551731716	0.134994034525919
GO:0005520	insulin-like growth factor binding	6/2246	19/18639	0.315789473684211	2.6206589492431	0.0205473471040315	0.136048284273607
GO:0033218	amide binding	41/2246	247/18639	0.165991902834008	1.37752585793548	0.0206099635944289	0.136048284273607
GO:0061650	ubiquitin-like protein conjugating enzyme activity	10/2246	41/18639	0.24390243902439	2.02408618030971	0.021138746111323	0.138030298932315
GO:0140318	protein transporter activity	10/2246	41/18639	0.24390243902439	2.02408618030971	0.021138746111323	0.138030298932315
GO:1990518	single-stranded 3'-5' DNA helicase activity	11/2246	47/18639	0.234042553191489	1.94226141982911	0.0216080924089131	0.139307271929741
GO:0140713	histone chaperone activity	29/2246	164/18639	0.176829268292683	1.46746248072454	0.0216458197805993	0.139307271929741
GO:0140296	general transcription initiation factor binding	12/2246	53/18639	0.226415094339623	1.87896302021203	0.0216802707970127	0.139307271929741
GO:0005518	collagen binding	15/2246	72/18639	0.208333333333333	1.72890694568121	0.0230833660912925	0.147538128244875
GO:0005522	profilin binding	4/2246	10/18639	0.4	3.31950133570793	0.0242424644689036	0.150651524460052
GO:0008641	ubiquitin-like modifier activating enzyme activity	4/2246	10/18639	0.4	3.31950133570793	0.0242424644689036	0.150651524460052
GO:0016868	intramolecular phosphotransferase activity	4/2246	10/18639	0.4	3.31950133570793	0.0242424644689036	0.150651524460052
GO:0030957	Tat protein binding	4/2246	10/18639	0.4	3.31950133570793	0.0242424644689036	0.150651524460052
GO:0001098	basal transcription machinery binding	13/2246	60/18639	0.216666666666667	1.79806322350846	0.0244752467714142	0.150651524460052
GO:0001099	basal RNA polymerase II transcription machinery binding	13/2246	60/18639	0.216666666666667	1.79806322350846	0.0244752467714142	0.150651524460052
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	13/2246	60/18639	0.216666666666667	1.79806322350846	0.0244752467714142	0.150651524460052
GO:0005537	D-mannose binding	7/2246	25/18639	0.28	2.32365093499555	0.0246928823204389	0.150651524460052
GO:0017025	TBP-class protein binding	7/2246	25/18639	0.28	2.32365093499555	0.0246928823204389	0.150651524460052
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	11/2246	48/18639	0.229166666666667	1.90179764024933	0.0250734513064947	0.151443645891228
GO:0043138	3'-5' DNA helicase activity	11/2246	48/18639	0.229166666666667	1.90179764024933	0.0250734513064947	0.151443645891228
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	6/2246	20/18639	0.3	2.48962600178094	0.0264336661370939	0.157299845781327
GO:0031418	L-ascorbic acid binding	6/2246	20/18639	0.3	2.48962600178094	0.0264336661370939	0.157299845781327
GO:0043024	ribosomal small subunit binding	6/2246	20/18639	0.3	2.48962600178094	0.0264336661370939	0.157299845781327
GO:0016763	pentosyltransferase activity	11/2246	49/18639	0.224489795918367	1.86298544350955	0.0289245106563565	0.171278474867052
GO:0030170	pyridoxal phosphate binding	12/2246	56/18639	0.214285714285714	1.77830428698639	0.0324134681447333	0.19068937764206
GO:0051059	NF-kappaB binding	8/2246	32/18639	0.25	2.07468833481745	0.0325182216839937	0.19068937764206
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	9/2246	38/18639	0.236842105263158	1.96549421193232	0.033456587297773	0.194141284347046
GO:0042162	telomeric DNA binding	9/2246	38/18639	0.236842105263158	1.96549421193232	0.033456587297773	0.194141284347046
GO:0019205	nucleobase-containing compound kinase activity	10/2246	44/18639	0.227272727272727	1.8860803043795	0.0335890135997787	0.194141284347046
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	22/2246	122/18639	0.180327868852459	1.49649650380275	0.0340719997461164	0.195836658980906
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4/2246	11/18639	0.363636363636364	3.0177284870072	0.0345308016249445	0.195836658980906
GO:0019206	nucleoside kinase activity	4/2246	11/18639	0.363636363636364	3.0177284870072	0.0345308016249445	0.195836658980906
GO:0032404	mismatch repair complex binding	4/2246	11/18639	0.363636363636364	3.0177284870072	0.0345308016249445	0.195836658980906
GO:0008142	oxysterol binding	5/2246	16/18639	0.3125	2.59336041852182	0.0353120668875615	0.198404543256625
GO:0034450	ubiquitin-ubiquitin ligase activity	5/2246	16/18639	0.3125	2.59336041852182	0.0353120668875615	0.198404543256625
GO:0070279	vitamin B6 binding	12/2246	57/18639	0.210526315789474	1.74710596616207	0.036714264087251	0.205278670306653
GO:0008266	poly(U) RNA binding	7/2246	27/18639	0.259259259259259	2.1515286435144	0.0368753902785957	0.205278670306653
GO:0005048	signal sequence binding	11/2246	51/18639	0.215686274509804	1.7899271908229	0.0378625457960889	0.209807134503098
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	8/2246	33/18639	0.242424242424242	2.01181899133814	0.0385414064187652	0.21259369385328
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	9/2246	39/18639	0.230769230769231	1.91509692444688	0.0390038073050988	0.214166360111633
GO:0030021	extracellular matrix structural constituent conferring compression resistance	6/2246	22/18639	0.272727272727273	2.2632963652554	0.0413093815696236	0.221785479716024
GO:0034062	5'-3' RNA polymerase activity	6/2246	22/18639	0.272727272727273	2.2632963652554	0.0413093815696236	0.221785479716024
GO:0061133	endopeptidase activator activity	6/2246	22/18639	0.272727272727273	2.2632963652554	0.0413093815696236	0.221785479716024
GO:0070034	telomerase RNA binding	6/2246	22/18639	0.272727272727273	2.2632963652554	0.0413093815696236	0.221785479716024
GO:0097747	RNA polymerase activity	6/2246	22/18639	0.272727272727273	2.2632963652554	0.0413093815696236	0.221785479716024
GO:0038024	cargo receptor activity	13/2246	65/18639	0.2	1.65975066785396	0.0443144792842476	0.235698873166116
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	9/2246	40/18639	0.225	1.86721950133571	0.0451432406700225	0.235698873166116
GO:0005092	GDP-dissociation inhibitor activity	5/2246	17/18639	0.294117647058824	2.44080980566759	0.0452049527027932	0.235698873166116
GO:0016018	cyclosporin A binding	5/2246	17/18639	0.294117647058824	2.44080980566759	0.0452049527027932	0.235698873166116
GO:0031489	myosin V binding	5/2246	17/18639	0.294117647058824	2.44080980566759	0.0452049527027932	0.235698873166116
GO:1990226	histone methyltransferase binding	5/2246	17/18639	0.294117647058824	2.44080980566759	0.0452049527027932	0.235698873166116
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	8/2246	34/18639	0.235294117647059	1.95264784453407	0.045266671005413	0.235698873166116
GO:0004859	phospholipase inhibitor activity	4/2246	12/18639	0.333333333333333	2.76625111308994	0.0469746470392921	0.240446498404512
GO:0031543	peptidyl-proline dioxygenase activity	4/2246	12/18639	0.333333333333333	2.76625111308994	0.0469746470392921	0.240446498404512
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	4/2246	12/18639	0.333333333333333	2.76625111308994	0.0469746470392921	0.240446498404512
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/2246	12/18639	0.333333333333333	2.76625111308994	0.0469746470392921	0.240446498404512
GO:0019887	protein kinase regulator activity	40/2246	255/18639	0.156862745098039	1.30176522968938	0.0484220092860866	0.246809228766214
GO:0000175	3'-5'-RNA exonuclease activity	8/2246	35/18639	0.228571428571429	1.89685790611881	0.052716802464795	0.266451453462227
GO:0061631	ubiquitin conjugating enzyme activity	8/2246	35/18639	0.228571428571429	1.89685790611881	0.052716802464795	0.266451453462227
GO:0070064	proline-rich region binding	5/2246	18/18639	0.277777777777778	2.30520926090828	0.0565849629601741	0.284810980232876
GO:0016879	ligase activity, forming carbon-nitrogen bonds	10/2246	48/18639	0.208333333333333	1.72890694568121	0.0570927019206621	0.286174207137593
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	12/2246	61/18639	0.19672131147541	1.63254164051209	0.0579271655750954	0.289157090969898
GO:0070840	dynein complex binding	6/2246	24/18639	0.25	2.07468833481745	0.0605845945210872	0.290607328777893
GO:0140658	ATP-dependent chromatin remodeler activity	26/2246	158/18639	0.164556962025316	1.36561763810769	0.0609087295700038	0.290607328777893
GO:0000510	H3-H4 histone complex chaperone activity	25/2246	151/18639	0.165562913907285	1.37396578464732	0.0613598331006402	0.290607328777893
GO:0140584	chromatin extrusion motor activity	25/2246	151/18639	0.165562913907285	1.37396578464732	0.0613598331006402	0.290607328777893
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	25/2246	151/18639	0.165562913907285	1.37396578464732	0.0613598331006402	0.290607328777893
GO:0140849	ATP-dependent H2AZ histone chaperone activity	25/2246	151/18639	0.165562913907285	1.37396578464732	0.0613598331006402	0.290607328777893
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	4/2246	13/18639	0.307692307692308	2.55346256592917	0.0615694042636857	0.290607328777893
GO:0005172	vascular endothelial growth factor receptor binding	4/2246	13/18639	0.307692307692308	2.55346256592917	0.0615694042636857	0.290607328777893
GO:0005542	folic acid binding	4/2246	13/18639	0.307692307692308	2.55346256592917	0.0615694042636857	0.290607328777893
GO:0009982	pseudouridine synthase activity	4/2246	13/18639	0.307692307692308	2.55346256592917	0.0615694042636857	0.290607328777893
GO:0019855	calcium channel inhibitor activity	4/2246	13/18639	0.307692307692308	2.55346256592917	0.0615694042636857	0.290607328777893
GO:0030955	potassium ion binding	4/2246	13/18639	0.307692307692308	2.55346256592917	0.0615694042636857	0.290607328777893
GO:0140666	annealing activity	4/2246	13/18639	0.307692307692308	2.55346256592917	0.0615694042636857	0.290607328777893
GO:0016769	transferase activity, transferring nitrogenous groups	7/2246	30/18639	0.233333333333333	1.93637577916296	0.0615856590787587	0.290607328777893
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	16/2246	89/18639	0.179775280898876	1.49191071267772	0.0651777064450898	0.303764890351619
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	16/2246	89/18639	0.179775280898876	1.49191071267772	0.0651777064450898	0.303764890351619
GO:0015616	DNA translocase activity	25/2246	152/18639	0.164473684210526	1.36492653606411	0.0653798605061433	0.303764890351619
GO:0140674	ATP-dependent histone chaperone activity	25/2246	152/18639	0.164473684210526	1.36492653606411	0.0653798605061433	0.303764890351619
GO:0048156	tau protein binding	9/2246	43/18639	0.209302325581395	1.73694837333554	0.0672923238117115	0.311452594500182
GO:0017022	myosin binding	14/2246	76/18639	0.184210526315789	1.52871772039181	0.0685187561323973	0.315918539724946
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	5/2246	19/18639	0.263157894736842	2.18388245770258	0.0694555400516536	0.317180357491459
GO:0031420	alkali metal ion binding	5/2246	19/18639	0.263157894736842	2.18388245770258	0.0694555400516536	0.317180357491459
GO:0061775	cohesin loader activity	25/2246	153/18639	0.163398692810458	1.35600544759311	0.0695801280920834	0.317180357491459
GO:0140793	histone H2AXY142 phosphatase activity	16/2246	90/18639	0.177777777777778	1.4753339269813	0.0707938129675822	0.321499722048268
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	22/2246	132/18639	0.166666666666667	1.38312555654497	0.0712322078521718	0.321770125434365
GO:0008327	methyl-CpG binding	7/2246	31/18639	0.225806451612903	1.87391204435125	0.0716237788383781	0.321770125434365
GO:0008483	transaminase activity	6/2246	25/18639	0.24	1.99170080142476	0.0719188194265552	0.321770125434365
GO:0019211	phosphatase activator activity	6/2246	25/18639	0.24	1.99170080142476	0.0719188194265552	0.321770125434365
GO:0097110	scaffold protein binding	13/2246	70/18639	0.185714285714286	1.54119704872154	0.0732840440572547	0.326668358749681
GO:0001046	core promoter sequence-specific DNA binding	9/2246	44/18639	0.204545454545455	1.69747227394155	0.0759588892947799	0.336269525351957
GO:0051117	ATPase binding	15/2246	84/18639	0.178571428571429	1.48192023915532	0.0759946857790432	0.336269525351957
GO:0004725	protein tyrosine phosphatase activity	17/2246	98/18639	0.173469387755102	1.43957966089374	0.0771335711758975	0.340063335695198
GO:0005161	platelet-derived growth factor receptor binding	4/2246	14/18639	0.285714285714286	2.37107238264852	0.0782587982867614	0.342524015689883
GO:0030983	mismatched DNA binding	4/2246	14/18639	0.285714285714286	2.37107238264852	0.0782587982867614	0.342524015689883
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	7/2246	32/18639	0.21875	1.81535229296527	0.0825733348416058	0.357521822539999
GO:0043425	bHLH transcription factor binding	7/2246	32/18639	0.21875	1.81535229296527	0.0825733348416058	0.357521822539999
GO:0140142	nucleocytoplasmic carrier activity	7/2246	32/18639	0.21875	1.81535229296527	0.0825733348416058	0.357521822539999
GO:0008408	3'-5' exonuclease activity	11/2246	58/18639	0.189655172413793	1.57390149537876	0.0837211564815633	0.357688222421649
GO:0000339	RNA cap binding	5/2246	20/18639	0.25	2.07468833481745	0.08379616468984	0.357688222421649
GO:0016408	C-acyltransferase activity	5/2246	20/18639	0.25	2.07468833481745	0.08379616468984	0.357688222421649
GO:0140664	ATP-dependent DNA damage sensor activity	5/2246	20/18639	0.25	2.07468833481745	0.08379616468984	0.357688222421649
GO:0004529	DNA exonuclease activity	6/2246	26/18639	0.230769230769231	1.91509692444688	0.0843816564445343	0.358919158397878
GO:0004540	RNA nuclease activity	20/2246	121/18639	0.165289256198347	1.37169476682146	0.0880298639632604	0.37312307251796
GO:0005080	protein kinase C binding	10/2246	52/18639	0.192307692307692	1.59591410370573	0.0893690625270056	0.377474921442737
GO:0016776	phosphotransferase activity, phosphate group as acceptor	8/2246	39/18639	0.205128205128205	1.70230837728612	0.0900285886221592	0.378935662214524
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	9/2246	46/18639	0.195652173913043	1.62366913159627	0.0952465595353118	0.398124027400196
GO:0030291	protein serine/threonine kinase inhibitor activity	9/2246	46/18639	0.195652173913043	1.62366913159627	0.0952465595353118	0.398124027400196
GO:0005523	tropomyosin binding	4/2246	15/18639	0.266666666666667	2.21300089047195	0.0969429363803337	0.401051599820011
GO:0016846	carbon-sulfur lyase activity	4/2246	15/18639	0.266666666666667	2.21300089047195	0.0969429363803337	0.401051599820011
GO:0061578	K63-linked deubiquitinase activity	4/2246	15/18639	0.266666666666667	2.21300089047195	0.0969429363803337	0.401051599820011
GO:0001671	ATPase activator activity	6/2246	27/18639	0.222222222222222	1.84416740872663	0.0979548753490881	0.401116913293893
GO:0004364	glutathione transferase activity	6/2246	27/18639	0.222222222222222	1.84416740872663	0.0979548753490881	0.401116913293893
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	6/2246	27/18639	0.222222222222222	1.84416740872663	0.0979548753490881	0.401116913293893
GO:0019200	carbohydrate kinase activity	5/2246	21/18639	0.238095238095238	1.9758936522071	0.099564381989656	0.403603266588941
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	5/2246	21/18639	0.238095238095238	1.9758936522071	0.099564381989656	0.403603266588941
GO:0051010	microtubule plus-end binding	5/2246	21/18639	0.238095238095238	1.9758936522071	0.099564381989656	0.403603266588941
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	8/2246	40/18639	0.2	1.65975066785396	0.101249925610193	0.406804789227911
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	11/2246	60/18639	0.183333333333333	1.52143811219947	0.10128946414322	0.406804789227911
GO:0016874	ligase activity	26/2246	167/18639	0.155688622754491	1.29202147797015	0.102385948190841	0.406804789227911
GO:0033192	calmodulin-dependent protein phosphatase activity	14/2246	81/18639	0.172839506172839	1.4343524290096	0.104058509827338	0.406804789227911
GO:0140791	histone H2AXS140 phosphatase activity	14/2246	81/18639	0.172839506172839	1.4343524290096	0.104058509827338	0.406804789227911
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	14/2246	81/18639	0.172839506172839	1.4343524290096	0.104058509827338	0.406804789227911
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	14/2246	81/18639	0.172839506172839	1.4343524290096	0.104058509827338	0.406804789227911
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	14/2246	81/18639	0.172839506172839	1.4343524290096	0.104058509827338	0.406804789227911
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	14/2246	81/18639	0.172839506172839	1.4343524290096	0.104058509827338	0.406804789227911
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	14/2246	81/18639	0.172839506172839	1.4343524290096	0.104058509827338	0.406804789227911
GO:1990439	MAP kinase serine/threonine phosphatase activity	14/2246	81/18639	0.172839506172839	1.4343524290096	0.104058509827338	0.406804789227911
GO:0019207	kinase regulator activity	42/2246	287/18639	0.146341463414634	1.21445170818583	0.105202832378144	0.409951682299349
GO:0004721	phosphoprotein phosphatase activity	27/2246	175/18639	0.154285714285714	1.2803790866302	0.105885895510248	0.410238161056734
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	7/2246	34/18639	0.205882352941176	1.70856686396731	0.107173636526539	0.410238161056734
GO:0030332	cyclin binding	7/2246	34/18639	0.205882352941176	1.70856686396731	0.107173636526539	0.410238161056734
GO:0090482	vitamin transmembrane transporter activity	7/2246	34/18639	0.205882352941176	1.70856686396731	0.107173636526539	0.410238161056734
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	3/2246	10/18639	0.3	2.48962600178094	0.109691163924938	0.410238161056734
GO:0003680	minor groove of adenine-thymine-rich DNA binding	3/2246	10/18639	0.3	2.48962600178094	0.109691163924938	0.410238161056734
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	3/2246	10/18639	0.3	2.48962600178094	0.109691163924938	0.410238161056734
GO:0031996	thioesterase binding	3/2246	10/18639	0.3	2.48962600178094	0.109691163924938	0.410238161056734
GO:0033204	ribonuclease P RNA binding	3/2246	10/18639	0.3	2.48962600178094	0.109691163924938	0.410238161056734
GO:0035374	chondroitin sulfate binding	3/2246	10/18639	0.3	2.48962600178094	0.109691163924938	0.410238161056734
GO:0051880	G-quadruplex DNA binding	3/2246	10/18639	0.3	2.48962600178094	0.109691163924938	0.410238161056734
GO:0140940	histone H2A methyltransferase activity	3/2246	10/18639	0.3	2.48962600178094	0.109691163924938	0.410238161056734
GO:1990259	histone H2AQ104 methyltransferase activity	3/2246	10/18639	0.3	2.48962600178094	0.109691163924938	0.410238161056734
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	14/2246	82/18639	0.170731707317073	1.4168603262168	0.112295330295065	0.417393104604426
GO:0033549	MAP kinase phosphatase activity	14/2246	82/18639	0.170731707317073	1.4168603262168	0.112295330295065	0.417393104604426
GO:0016877	ligase activity, forming carbon-sulfur bonds	8/2246	41/18639	0.195121951219512	1.61926894424777	0.113214876118202	0.419520154450271
GO:0005149	interleukin-1 receptor binding	4/2246	16/18639	0.25	2.07468833481745	0.117486559544591	0.431379221671326
GO:0055102	lipase inhibitor activity	4/2246	16/18639	0.25	2.07468833481745	0.117486559544591	0.431379221671326
GO:0097027	ubiquitin-protein transferase activator activity	4/2246	16/18639	0.25	2.07468833481745	0.117486559544591	0.431379221671326
GO:0140313	molecular sequestering activity	10/2246	55/18639	0.181818181818182	1.5088642435036	0.119527837634952	0.437544326857642
GO:0016229	steroid dehydrogenase activity	7/2246	35/18639	0.2	1.65975066785396	0.120787845041975	0.43992540630666
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	14/2246	83/18639	0.168674698795181	1.39978971987684	0.120906651402161	0.43992540630666
GO:0042056	chemoattractant activity	8/2246	42/18639	0.19047619047619	1.58071492176568	0.125906959078976	0.456743563265474
GO:0003785	actin monomer binding	6/2246	29/18639	0.206896551724138	1.7169834495041	0.128299720009743	0.461151004012371
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	6/2246	29/18639	0.206896551724138	1.7169834495041	0.128299720009743	0.461151004012371
GO:0097472	cyclin-dependent protein kinase activity	6/2246	29/18639	0.206896551724138	1.7169834495041	0.128299720009743	0.461151004012371
GO:0072341	modified amino acid binding	15/2246	91/18639	0.164835164835165	1.36792637460491	0.128648914198816	0.461151004012371
GO:0032182	ubiquitin-like protein binding	19/2246	120/18639	0.158333333333333	1.31396927871772	0.129373434547838	0.462376061934284
GO:0017018	myosin phosphatase activity	14/2246	84/18639	0.166666666666667	1.38312555654497	0.129889044526785	0.462849456602822
GO:0008028	monocarboxylic acid transmembrane transporter activity	12/2246	70/18639	0.171428571428571	1.42264342958911	0.131378297908272	0.466779364332919
GO:0031406	carboxylic acid binding	28/2246	187/18639	0.149732620320856	1.24259408288532	0.132221819227222	0.468398702716962
GO:0099186	structural constituent of postsynapse	5/2246	23/18639	0.217391304347826	1.80407681288474	0.135118755901617	0.474130003316298
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	3/2246	11/18639	0.272727272727273	2.2632963652554	0.137876299787435	0.474130003316298
GO:0002162	dystroglycan binding	3/2246	11/18639	0.272727272727273	2.2632963652554	0.137876299787435	0.474130003316298
GO:0003953	NAD+ nucleosidase activity	3/2246	11/18639	0.272727272727273	2.2632963652554	0.137876299787435	0.474130003316298
GO:0008199	ferric iron binding	3/2246	11/18639	0.272727272727273	2.2632963652554	0.137876299787435	0.474130003316298
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	3/2246	11/18639	0.272727272727273	2.2632963652554	0.137876299787435	0.474130003316298
GO:0019215	intermediate filament binding	3/2246	11/18639	0.272727272727273	2.2632963652554	0.137876299787435	0.474130003316298
GO:0032794	GTPase activating protein binding	3/2246	11/18639	0.272727272727273	2.2632963652554	0.137876299787435	0.474130003316298
GO:0047676	arachidonate-CoA ligase activity	3/2246	11/18639	0.272727272727273	2.2632963652554	0.137876299787435	0.474130003316298
GO:0097493	structural molecule activity conferring elasticity	3/2246	11/18639	0.272727272727273	2.2632963652554	0.137876299787435	0.474130003316298
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	8/2246	43/18639	0.186046511627907	1.54395410963159	0.139304589997208	0.474130003316298
GO:0004029	aldehyde dehydrogenase (NAD+) activity	4/2246	17/18639	0.235294117647059	1.95264784453407	0.139727053957452	0.474130003316298
GO:0004550	nucleoside diphosphate kinase activity	4/2246	17/18639	0.235294117647059	1.95264784453407	0.139727053957452	0.474130003316298
GO:0032183	SUMO binding	4/2246	17/18639	0.235294117647059	1.95264784453407	0.139727053957452	0.474130003316298
GO:0070492	oligosaccharide binding	4/2246	17/18639	0.235294117647059	1.95264784453407	0.139727053957452	0.474130003316298
GO:0061134	peptidase regulator activity	33/2246	226/18639	0.146017699115044	1.21176486812347	0.140121957040745	0.47413816275972
GO:0048020	CCR chemokine receptor binding	9/2246	50/18639	0.18	1.49377560106857	0.141488139555482	0.477423666433023
GO:0043177	organic acid binding	28/2246	189/18639	0.148148148148148	1.22944493915108	0.144748955679652	0.48706612384685
GO:0051219	phosphoprotein binding	15/2246	93/18639	0.161290322580645	1.33850860310803	0.146781057721575	0.49253199368795
GO:0030547	signaling receptor inhibitor activity	8/2246	44/18639	0.181818181818182	1.5088642435036	0.153381412375525	0.513254144458822
GO:0030544	Hsp70 protein binding	9/2246	51/18639	0.176470588235294	1.46448588340056	0.154567927908546	0.513509546008142
GO:0050699	WW domain binding	5/2246	24/18639	0.208333333333333	1.72890694568121	0.154733008896493	0.513509546008142
GO:0140612	DNA damage sensor activity	5/2246	24/18639	0.208333333333333	1.72890694568121	0.154733008896493	0.513509546008142
GO:1901681	sulfur compound binding	39/2246	275/18639	0.141818181818182	1.17691410993281	0.158297652284773	0.523900175232892
GO:0072349	modified amino acid transmembrane transporter activity	6/2246	31/18639	0.193548387096774	1.60621032372964	0.162583304779476	0.533222140813144
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	4/2246	18/18639	0.222222222222222	1.84416740872663	0.163481937099532	0.533222140813144
GO:1990381	ubiquitin-specific protease binding	4/2246	18/18639	0.222222222222222	1.84416740872663	0.163481937099532	0.533222140813144
GO:0019001	guanyl nucleotide binding	55/2246	400/18639	0.1375	1.1410785841496	0.163680089067432	0.533222140813144
GO:0032561	guanyl ribonucleotide binding	55/2246	400/18639	0.1375	1.1410785841496	0.163680089067432	0.533222140813144
GO:0045309	protein phosphorylated amino acid binding	10/2246	59/18639	0.169491525423729	1.4065683625881	0.167344246463354	0.533222140813144
GO:0070063	RNA polymerase binding	10/2246	59/18639	0.169491525423729	1.4065683625881	0.167344246463354	0.533222140813144
GO:0008009	chemokine activity	8/2246	45/18639	0.177777777777778	1.4753339269813	0.16810667516813	0.533222140813144
GO:0000340	RNA 7-methylguanosine cap binding	3/2246	12/18639	0.25	2.07468833481745	0.168176850703483	0.533222140813144
GO:0004526	ribonuclease P activity	3/2246	12/18639	0.25	2.07468833481745	0.168176850703483	0.533222140813144
GO:0005049	nuclear export signal receptor activity	3/2246	12/18639	0.25	2.07468833481745	0.168176850703483	0.533222140813144
GO:0016801	hydrolase activity, acting on ether bonds	3/2246	12/18639	0.25	2.07468833481745	0.168176850703483	0.533222140813144
GO:0016803	ether hydrolase activity	3/2246	12/18639	0.25	2.07468833481745	0.168176850703483	0.533222140813144
GO:0017166	vinculin binding	3/2246	12/18639	0.25	2.07468833481745	0.168176850703483	0.533222140813144
GO:0036009	protein-glutamine N-methyltransferase activity	3/2246	12/18639	0.25	2.07468833481745	0.168176850703483	0.533222140813144
GO:0045295	gamma-catenin binding	3/2246	12/18639	0.25	2.07468833481745	0.168176850703483	0.533222140813144
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	5/2246	25/18639	0.2	1.65975066785396	0.175436556263978	0.553335143516671
GO:0017056	structural constituent of nuclear pore	5/2246	25/18639	0.2	1.65975066785396	0.175436556263978	0.553335143516671
GO:0070717	poly-purine tract binding	6/2246	32/18639	0.1875	1.55601625111309	0.181047143995908	0.569544140487127
GO:0003725	double-stranded RNA binding	12/2246	75/18639	0.16	1.32780053428317	0.187486225898666	0.587049527625234
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	4/2246	19/18639	0.210526315789474	1.74710596616207	0.188555642978966	0.587049527625234
GO:0030506	ankyrin binding	4/2246	19/18639	0.210526315789474	1.74710596616207	0.188555642978966	0.587049527625234
GO:0140036	ubiquitin-modified protein reader activity	4/2246	19/18639	0.210526315789474	1.74710596616207	0.188555642978966	0.587049527625234
GO:0016836	hydro-lyase activity	10/2246	61/18639	0.163934426229508	1.36045136709341	0.194226974123297	0.601424460706307
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	26/2246	181/18639	0.143646408839779	1.19208611503323	0.19625080923845	0.601424460706307
GO:0003925	G protein activity	9/2246	54/18639	0.166666666666667	1.38312555654497	0.197098079917349	0.601424460706307
GO:0050661	NADP binding	9/2246	54/18639	0.166666666666667	1.38312555654497	0.197098079917349	0.601424460706307
GO:0140463	chromatin-protein adaptor activity	9/2246	54/18639	0.166666666666667	1.38312555654497	0.197098079917349	0.601424460706307
GO:0008198	ferrous iron binding	5/2246	26/18639	0.192307692307692	1.59591410370573	0.197116294316226	0.601424460706307
GO:0097602	cullin family protein binding	5/2246	26/18639	0.192307692307692	1.59591410370573	0.197116294316226	0.601424460706307
GO:0031490	chromatin DNA binding	19/2246	128/18639	0.1484375	1.23184619879786	0.197980307343268	0.601424460706307
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3/2246	13/18639	0.230769230769231	1.91509692444688	0.200159084635422	0.601424460706307
GO:0061459	L-arginine transmembrane transporter activity	3/2246	13/18639	0.230769230769231	1.91509692444688	0.200159084635422	0.601424460706307
GO:0070700	BMP receptor binding	3/2246	13/18639	0.230769230769231	1.91509692444688	0.200159084635422	0.601424460706307
GO:0140852	histone ubiquitin ligase activity	3/2246	13/18639	0.230769230769231	1.91509692444688	0.200159084635422	0.601424460706307
GO:0019956	chemokine binding	6/2246	33/18639	0.181818181818182	1.5088642435036	0.200295823816865	0.601424460706307
GO:0061791	GTPase motor activity	7/2246	40/18639	0.175	1.45228183437222	0.200640776212452	0.601424460706307
GO:1990606	membrane scission GTPase motor activity	7/2246	40/18639	0.175	1.45228183437222	0.200640776212452	0.601424460706307
GO:0046982	protein heterodimerization activity	50/2246	369/18639	0.13550135501355	1.12449232239428	0.206070536577066	0.616171307388852
GO:0016922	nuclear receptor binding	20/2246	137/18639	0.145985401459854	1.21149683784961	0.211604604953859	0.631156451319165
GO:0005525	GTP binding	51/2246	378/18639	0.134920634920635	1.11967306958402	0.212524666721092	0.632339402460786
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	4/2246	20/18639	0.2	1.65975066785396	0.214745512551247	0.635815145004672
GO:0061608	nuclear import signal receptor activity	4/2246	20/18639	0.2	1.65975066785396	0.214745512551247	0.635815145004672
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	7/2246	41/18639	0.170731707317073	1.4168603262168	0.218640226231856	0.644280921024109
GO:0140098	catalytic activity, acting on RNA	52/2246	387/18639	0.134366925064599	1.11507796806726	0.218918928993469	0.644280921024109
GO:0001221	transcription coregulator binding	17/2246	115/18639	0.147826086956522	1.22677223276162	0.21920484978552	0.644280921024109
GO:0016741	transferase activity, transferring one-carbon groups	30/2246	215/18639	0.13953488372093	1.15796558222369	0.221160211990387	0.648450330301913
GO:0070851	growth factor receptor binding	20/2246	139/18639	0.143884892086331	1.19406522867192	0.231099339833271	0.67291832379324
GO:0140299	molecular sensor activity	11/2246	71/18639	0.154929577464789	1.28572234833758	0.231663326683256	0.67291832379324
GO:0050660	flavin adenine dinucleotide binding	13/2246	86/18639	0.151162790697674	1.25446271407567	0.232547068990016	0.67291832379324
GO:0004705	JUN kinase activity	3/2246	14/18639	0.214285714285714	1.77830428698639	0.233404617275967	0.67291832379324
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/2246	14/18639	0.214285714285714	1.77830428698639	0.233404617275967	0.67291832379324
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	3/2246	14/18639	0.214285714285714	1.77830428698639	0.233404617275967	0.67291832379324
GO:0098847	sequence-specific single stranded DNA binding	3/2246	14/18639	0.214285714285714	1.77830428698639	0.233404617275967	0.67291832379324
GO:0035198	miRNA binding	7/2246	42/18639	0.166666666666667	1.38312555654497	0.237186879662432	0.682188677216991
GO:0004536	DNA nuclease activity	10/2246	64/18639	0.15625	1.29668020926091	0.237749530718835	0.682188677216991
GO:0005154	epidermal growth factor receptor binding	6/2246	35/18639	0.171428571428571	1.42264342958911	0.240829074759168	0.689035664348781
GO:0072542	protein phosphatase activator activity	4/2246	21/18639	0.19047619047619	1.58071492176568	0.241846955036327	0.689035664348781
GO:1904047	S-adenosyl-L-methionine binding	4/2246	21/18639	0.19047619047619	1.58071492176568	0.241846955036327	0.689035664348781
GO:0042379	chemokine receptor binding	11/2246	72/18639	0.152777777777778	1.26786509349956	0.245921990907469	0.698997094155817
GO:0004722	protein serine/threonine phosphatase activity	15/2246	103/18639	0.145631067961165	1.20855631154415	0.255718330200774	0.724855299516588
GO:0008200	ion channel inhibitor activity	7/2246	43/18639	0.162790697674419	1.35095984592764	0.256219547097337	0.724855299516588
GO:0004521	RNA endonuclease activity	11/2246	73/18639	0.150684931506849	1.25049707852011	0.260487218753533	0.733954835494839
GO:0005126	cytokine receptor binding	37/2246	275/18639	0.134545454545455	1.11655954019267	0.26065117916166	0.733954835494839
GO:0044390	ubiquitin-like protein conjugating enzyme binding	6/2246	36/18639	0.166666666666667	1.38312555654497	0.261946626716727	0.735887267613503
GO:0016407	acetyltransferase activity	14/2246	96/18639	0.145833333333333	1.21023486197685	0.263674544998083	0.7390228546582
GO:0106222	lncRNA binding	5/2246	29/18639	0.172413793103448	1.43081954125342	0.26680358814067	0.739506190617502
GO:0004467	long-chain fatty acid-CoA ligase activity	3/2246	15/18639	0.2	1.65975066785396	0.267520037499875	0.739506190617502
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/2246	15/18639	0.2	1.65975066785396	0.267520037499875	0.739506190617502
GO:0031005	filamin binding	3/2246	15/18639	0.2	1.65975066785396	0.267520037499875	0.739506190617502
GO:0140161	monocarboxylate:sodium symporter activity	3/2246	15/18639	0.2	1.65975066785396	0.267520037499875	0.739506190617502
GO:0140776	protein-containing complex destabilizing activity	3/2246	15/18639	0.2	1.65975066785396	0.267520037499875	0.739506190617502
GO:0008649	rRNA methyltransferase activity	4/2246	22/18639	0.181818181818182	1.5088642435036	0.269657788234932	0.74201960862824
GO:0140035	ubiquitin-like protein reader activity	4/2246	22/18639	0.181818181818182	1.5088642435036	0.269657788234932	0.74201960862824
GO:0016248	channel inhibitor activity	7/2246	44/18639	0.159090909090909	1.32025621306565	0.275675410423085	0.756854308616106
GO:0070888	E-box binding	9/2246	59/18639	0.152542372881356	1.26591152632929	0.277071368100196	0.758961933480809
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	46/2246	349/18639	0.131805157593123	1.09381849170892	0.279127930013409	0.7628654738828
GO:0002020	protease binding	19/2246	136/18639	0.139705882352941	1.15938465769211	0.280659855150554	0.765320778830403
GO:0019003	GDP binding	11/2246	75/18639	0.146666666666667	1.21715048975957	0.290431302537741	0.788636187744685
GO:0015215	nucleotide transmembrane transporter activity	5/2246	30/18639	0.166666666666667	1.38312555654497	0.291168658720306	0.788636187744685
GO:0098918	structural constituent of synapse	5/2246	30/18639	0.166666666666667	1.38312555654497	0.291168658720306	0.788636187744685
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	9/2246	60/18639	0.15	1.24481300089047	0.294103632542457	0.791733020692137
GO:0051539	4 iron, 4 sulfur cluster binding	7/2246	45/18639	0.155555555555556	1.29091718610864	0.295490703759524	0.791733020692137
GO:0141110	transporter inhibitor activity	7/2246	45/18639	0.155555555555556	1.29091718610864	0.295490703759524	0.791733020692137
GO:0008171	O-methyltransferase activity	4/2246	23/18639	0.173913043478261	1.44326145030779	0.297981795041945	0.791733020692137
GO:0043274	phospholipase binding	4/2246	23/18639	0.173913043478261	1.44326145030779	0.297981795041945	0.791733020692137
GO:0140102	catalytic activity, acting on a rRNA	4/2246	23/18639	0.173913043478261	1.44326145030779	0.297981795041945	0.791733020692137
GO:1990841	promoter-specific chromatin binding	10/2246	68/18639	0.147058823529412	1.2204049028338	0.300535961231893	0.791733020692137
GO:0004707	MAP kinase activity	3/2246	16/18639	0.1875	1.55601625111309	0.302143147797248	0.791733020692137
GO:0005159	insulin-like growth factor receptor binding	3/2246	16/18639	0.1875	1.55601625111309	0.302143147797248	0.791733020692137
GO:0005521	lamin binding	3/2246	16/18639	0.1875	1.55601625111309	0.302143147797248	0.791733020692137
GO:0008296	3'-5'-DNA exonuclease activity	3/2246	16/18639	0.1875	1.55601625111309	0.302143147797248	0.791733020692137
GO:0022858	alanine transmembrane transporter activity	3/2246	16/18639	0.1875	1.55601625111309	0.302143147797248	0.791733020692137
GO:0030275	LRR domain binding	3/2246	16/18639	0.1875	1.55601625111309	0.302143147797248	0.791733020692137
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	3/2246	16/18639	0.1875	1.55601625111309	0.302143147797248	0.791733020692137
GO:0070411	I-SMAD binding	3/2246	16/18639	0.1875	1.55601625111309	0.302143147797248	0.791733020692137
GO:0004518	nuclease activity	28/2246	209/18639	0.133971291866029	1.1117947057395	0.303426192413303	0.792643359041617
GO:0005246	calcium channel regulator activity	8/2246	53/18639	0.150943396226415	1.25264201347469	0.304459038572277	0.792643359041617
GO:0005544	calcium-dependent phospholipid binding	8/2246	53/18639	0.150943396226415	1.25264201347469	0.304459038572277	0.792643359041617
GO:0000146	microfilament motor activity	6/2246	38/18639	0.157894736842105	1.31032947462155	0.305455117941324	0.793526413920687
GO:0005539	glycosaminoglycan binding	32/2246	242/18639	0.132231404958678	1.09735581345717	0.314217422240885	0.814537867096543
GO:0005164	tumor necrosis factor receptor binding	5/2246	31/18639	0.161290322580645	1.33850860310803	0.315896611401235	0.816159451693422
GO:0043130	ubiquitin binding	14/2246	100/18639	0.14	1.16182546749777	0.316607922709126	0.816159451693422
GO:0002039	p53 binding	10/2246	69/18639	0.144927536231884	1.20271787525649	0.31686985334786	0.816159451693422
GO:0015485	cholesterol binding	8/2246	54/18639	0.148148148148148	1.22944493915108	0.323130509642699	0.827012009305624
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	4/2246	24/18639	0.166666666666667	1.38312555654497	0.326631552271036	0.827012009305624
GO:0005504	fatty acid binding	7/2246	47/18639	0.148936170212766	1.23598453989125	0.335943582113964	0.827012009305624
GO:0043495	protein-membrane adaptor activity	7/2246	47/18639	0.148936170212766	1.23598453989125	0.335943582113964	0.827012009305624
GO:0140938	histone H3 methyltransferase activity	7/2246	47/18639	0.148936170212766	1.23598453989125	0.335943582113964	0.827012009305624
GO:0004549	tRNA-specific ribonuclease activity	3/2246	17/18639	0.176470588235294	1.46448588340056	0.336946596477203	0.827012009305624
GO:0004659	prenyltransferase activity	3/2246	17/18639	0.176470588235294	1.46448588340056	0.336946596477203	0.827012009305624
GO:0017110	nucleoside diphosphate phosphatase activity	3/2246	17/18639	0.176470588235294	1.46448588340056	0.336946596477203	0.827012009305624
GO:0048038	quinone binding	3/2246	17/18639	0.176470588235294	1.46448588340056	0.336946596477203	0.827012009305624
GO:0070402	NADPH binding	3/2246	17/18639	0.176470588235294	1.46448588340056	0.336946596477203	0.827012009305624
GO:0042910	xenobiotic transmembrane transporter activity	5/2246	32/18639	0.15625	1.29668020926091	0.340868734994814	0.827012009305624
GO:0004862	cAMP-dependent protein kinase inhibitor activity	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0004935	adrenergic receptor activity	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0005345	purine nucleobase transmembrane transporter activity	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0008190	eukaryotic initiation factor 4E binding	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0016783	sulfurtransferase activity	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0019911	structural constituent of myelin sheath	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0071723	lipopeptide binding	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0098505	G-rich strand telomeric DNA binding	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0141109	transporter activator activity	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:1990757	ubiquitin ligase activator activity	2/2246	10/18639	0.2	1.65975066785396	0.343675520423364	0.827012009305624
GO:0033293	monocarboxylic acid binding	11/2246	79/18639	0.139240506329114	1.15552261686035	0.352796977522238	0.847273854566329
GO:0140311	protein sequestering activity	5/2246	33/18639	0.151515151515152	1.25738686958634	0.365971040562304	0.875431716830224
GO:0140416	transcription regulator inhibitor activity	5/2246	33/18639	0.151515151515152	1.25738686958634	0.365971040562304	0.875431716830224
GO:0004896	cytokine receptor activity	13/2246	96/18639	0.135416666666667	1.12378951469279	0.371174225594288	0.877453354611827
GO:0008308	voltage-gated monoatomic anion channel activity	3/2246	18/18639	0.166666666666667	1.38312555654497	0.371639528352738	0.877453354611827
GO:0008409	5'-3' exonuclease activity	3/2246	18/18639	0.166666666666667	1.38312555654497	0.371639528352738	0.877453354611827
GO:0017128	phospholipid scramblase activity	3/2246	18/18639	0.166666666666667	1.38312555654497	0.371639528352738	0.877453354611827
GO:0031690	adrenergic receptor binding	3/2246	18/18639	0.166666666666667	1.38312555654497	0.371639528352738	0.877453354611827
GO:0035615	clathrin adaptor activity	3/2246	18/18639	0.166666666666667	1.38312555654497	0.371639528352738	0.877453354611827
GO:0016247	channel regulator activity	22/2246	168/18639	0.130952380952381	1.0867415087139	0.372294386363099	0.877453354611827
GO:0015175	neutral L-amino acid transmembrane transporter activity	6/2246	41/18639	0.146341463414634	1.21445170818583	0.372627128241612	0.877453354611827
GO:0016791	phosphatase activity	35/2246	273/18639	0.128205128205128	1.06394273580382	0.374059885749067	0.879113505807145
GO:0043539	protein serine/threonine kinase activator activity	10/2246	73/18639	0.136986301369863	1.13681552592737	0.383752443819891	0.87926296471427
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	4/2246	26/18639	0.153846153846154	1.27673128296459	0.384215018186486	0.87926296471427
GO:0008143	poly(A) binding	4/2246	26/18639	0.153846153846154	1.27673128296459	0.384215018186486	0.87926296471427
GO:0050681	nuclear androgen receptor binding	4/2246	26/18639	0.153846153846154	1.27673128296459	0.384215018186486	0.87926296471427
GO:0015101	organic cation transmembrane transporter activity	11/2246	81/18639	0.135802469135802	1.12699119422183	0.384764262401664	0.87926296471427
GO:0010854	adenylate cyclase regulator activity	2/2246	11/18639	0.181818181818182	1.5088642435036	0.389408680564681	0.87926296471427
GO:0015173	aromatic amino acid transmembrane transporter activity	2/2246	11/18639	0.181818181818182	1.5088642435036	0.389408680564681	0.87926296471427
GO:0015205	nucleobase transmembrane transporter activity	2/2246	11/18639	0.181818181818182	1.5088642435036	0.389408680564681	0.87926296471427
GO:0015217	ADP transmembrane transporter activity	2/2246	11/18639	0.181818181818182	1.5088642435036	0.389408680564681	0.87926296471427
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/2246	11/18639	0.181818181818182	1.5088642435036	0.389408680564681	0.87926296471427
GO:0019107	myristoyltransferase activity	2/2246	11/18639	0.181818181818182	1.5088642435036	0.389408680564681	0.87926296471427
GO:0032050	clathrin heavy chain binding	2/2246	11/18639	0.181818181818182	1.5088642435036	0.389408680564681	0.87926296471427
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/2246	11/18639	0.181818181818182	1.5088642435036	0.389408680564681	0.87926296471427
GO:0034713	type I transforming growth factor beta receptor binding	2/2246	11/18639	0.181818181818182	1.5088642435036	0.389408680564681	0.87926296471427
GO:0035252	UDP-xylosyltransferase activity	2/2246	11/18639	0.181818181818182	1.5088642435036	0.389408680564681	0.87926296471427
GO:0042285	xylosyltransferase activity	2/2246	11/18639	0.181818181818182	1.5088642435036	0.389408680564681	0.87926296471427
GO:0048185	activin binding	2/2246	11/18639	0.181818181818182	1.5088642435036	0.389408680564681	0.87926296471427
GO:0050998	nitric-oxide synthase binding	2/2246	11/18639	0.181818181818182	1.5088642435036	0.389408680564681	0.87926296471427
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/2246	11/18639	0.181818181818182	1.5088642435036	0.389408680564681	0.87926296471427
GO:0140031	phosphorylation-dependent protein binding	2/2246	11/18639	0.181818181818182	1.5088642435036	0.389408680564681	0.87926296471427
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/2246	11/18639	0.181818181818182	1.5088642435036	0.389408680564681	0.87926296471427
GO:0016831	carboxy-lyase activity	5/2246	34/18639	0.147058823529412	1.2204049028338	0.391095258204733	0.881423641625592
GO:0141108	transporter regulator activity	22/2246	170/18639	0.129411764705882	1.07395631449374	0.394421996812542	0.882444006709444
GO:0004520	DNA endonuclease activity	6/2246	42/18639	0.142857142857143	1.18553619132426	0.395200503004809	0.882444006709444
GO:0019894	kinesin binding	6/2246	42/18639	0.142857142857143	1.18553619132426	0.395200503004809	0.882444006709444
GO:0043175	RNA polymerase core enzyme binding	6/2246	42/18639	0.142857142857143	1.18553619132426	0.395200503004809	0.882444006709444
GO:0048487	beta-tubulin binding	6/2246	42/18639	0.142857142857143	1.18553619132426	0.395200503004809	0.882444006709444
GO:0005006	epidermal growth factor receptor activity	7/2246	50/18639	0.14	1.16182546749777	0.397737364642351	0.884837452095691
GO:0005007	fibroblast growth factor receptor activity	7/2246	50/18639	0.14	1.16182546749777	0.397737364642351	0.884837452095691
GO:0061980	regulatory RNA binding	8/2246	58/18639	0.137931034482759	1.14465563300273	0.399300909762684	0.886682902561253
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/2246	19/18639	0.157894736842105	1.31032947462155	0.405967756860321	0.893276958628903
GO:0015245	fatty acid transmembrane transporter activity	3/2246	19/18639	0.157894736842105	1.31032947462155	0.405967756860321	0.893276958628903
GO:0050145	nucleoside monophosphate kinase activity	3/2246	19/18639	0.157894736842105	1.31032947462155	0.405967756860321	0.893276958628903
GO:0070003	threonine-type peptidase activity	3/2246	19/18639	0.157894736842105	1.31032947462155	0.405967756860321	0.893276958628903
GO:0097001	ceramide binding	3/2246	19/18639	0.157894736842105	1.31032947462155	0.405967756860321	0.893276958628903
GO:0008514	organic anion transmembrane transporter activity	34/2246	269/18639	0.12639405204461	1.04891306146905	0.41024352471689	0.897795289924041
GO:0008168	methyltransferase activity	26/2246	204/18639	0.127450980392157	1.05768424912262	0.411319132308723	0.897795289924041
GO:0005385	zinc ion transmembrane transporter activity	4/2246	27/18639	0.148148148148148	1.22944493915108	0.412834503011071	0.897795289924041
GO:0023026	MHC class II protein complex binding	4/2246	27/18639	0.148148148148148	1.22944493915108	0.412834503011071	0.897795289924041
GO:0035401	histone H3Y41 kinase activity	15/2246	115/18639	0.130434782608696	1.08244608773085	0.413223659931926	0.897795289924041
GO:0101005	deubiquitinase activity	15/2246	115/18639	0.130434782608696	1.08244608773085	0.413223659931926	0.897795289924041
GO:0140801	histone H2AXY142 kinase activity	15/2246	115/18639	0.130434782608696	1.08244608773085	0.413223659931926	0.897795289924041
GO:0008201	heparin binding	22/2246	172/18639	0.127906976744186	1.06146845037172	0.416707072549306	0.90109946311858
GO:0004712	protein serine/threonine/tyrosine kinase activity	6/2246	43/18639	0.13953488372093	1.15796558222369	0.417737955314129	0.90109946311858
GO:0042054	histone methyltransferase activity	9/2246	67/18639	0.134328358208955	1.1147579112452	0.418188712544391	0.90109946311858
GO:0016830	carbon-carbon lyase activity	7/2246	51/18639	0.137254901960784	1.13904457597821	0.41839190388822	0.90109946311858
GO:0001786	phosphatidylserine binding	8/2246	59/18639	0.135593220338983	1.12525469007048	0.418474171199937	0.90109946311858
GO:0004300	enoyl-CoA hydratase activity	2/2246	12/18639	0.166666666666667	1.38312555654497	0.433655046536921	0.910962061402435
GO:0005095	GTPase inhibitor activity	2/2246	12/18639	0.166666666666667	1.38312555654497	0.433655046536921	0.910962061402435
GO:0008603	cAMP-dependent protein kinase regulator activity	2/2246	12/18639	0.166666666666667	1.38312555654497	0.433655046536921	0.910962061402435
GO:0015132	prostaglandin transmembrane transporter activity	2/2246	12/18639	0.166666666666667	1.38312555654497	0.433655046536921	0.910962061402435
GO:0015368	calcium:monoatomic cation antiporter activity	2/2246	12/18639	0.166666666666667	1.38312555654497	0.433655046536921	0.910962061402435
GO:0016208	AMP binding	2/2246	12/18639	0.166666666666667	1.38312555654497	0.433655046536921	0.910962061402435
GO:0016273	arginine N-methyltransferase activity	2/2246	12/18639	0.166666666666667	1.38312555654497	0.433655046536921	0.910962061402435
GO:0016274	protein-arginine N-methyltransferase activity	2/2246	12/18639	0.166666666666667	1.38312555654497	0.433655046536921	0.910962061402435
GO:0016423	tRNA (guanine) methyltransferase activity	2/2246	12/18639	0.166666666666667	1.38312555654497	0.433655046536921	0.910962061402435
GO:0035197	siRNA binding	2/2246	12/18639	0.166666666666667	1.38312555654497	0.433655046536921	0.910962061402435
GO:0035497	cAMP response element binding	2/2246	12/18639	0.166666666666667	1.38312555654497	0.433655046536921	0.910962061402435
GO:0042301	phosphate ion binding	2/2246	12/18639	0.166666666666667	1.38312555654497	0.433655046536921	0.910962061402435
GO:0043047	single-stranded telomeric DNA binding	2/2246	12/18639	0.166666666666667	1.38312555654497	0.433655046536921	0.910962061402435
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/2246	12/18639	0.166666666666667	1.38312555654497	0.433655046536921	0.910962061402435
GO:0032934	sterol binding	9/2246	68/18639	0.132352941176471	1.09836441255042	0.436135742405619	0.910962061402435
GO:0004714	transmembrane receptor protein tyrosine kinase activity	8/2246	60/18639	0.133333333333333	1.10650044523598	0.437608100224165	0.910962061402435
GO:0030742	GTP-dependent protein binding	3/2246	20/18639	0.15	1.24481300089047	0.439712858797216	0.910962061402435
GO:0042288	MHC class I protein binding	3/2246	20/18639	0.15	1.24481300089047	0.439712858797216	0.910962061402435
GO:0140939	histone H4 methyltransferase activity	3/2246	20/18639	0.15	1.24481300089047	0.439712858797216	0.910962061402435
GO:0001223	transcription coactivator binding	6/2246	44/18639	0.136363636363636	1.1316481826277	0.44016888345482	0.910962061402435
GO:0000993	RNA polymerase II complex binding	5/2246	36/18639	0.138888888888889	1.15260463045414	0.441009460079359	0.910962061402435
GO:0046625	sphingolipid binding	4/2246	28/18639	0.142857142857143	1.18553619132426	0.441152985033464	0.910962061402435
GO:0046875	ephrin receptor binding	4/2246	28/18639	0.142857142857143	1.18553619132426	0.441152985033464	0.910962061402435
GO:0046966	nuclear thyroid hormone receptor binding	4/2246	28/18639	0.142857142857143	1.18553619132426	0.441152985033464	0.910962061402435
GO:0042277	peptide binding	31/2246	249/18639	0.124497991967871	1.03317812657576	0.451836222372697	0.931177195115606
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	21/2246	167/18639	0.125748502994012	1.04355580912974	0.452484282725878	0.931177195115606
GO:0061135	endopeptidase regulator activity	23/2246	184/18639	0.125	1.03734416740873	0.45906884835391	0.940887883872574
GO:0042562	hormone binding	12/2246	94/18639	0.127659574468085	1.05941531990678	0.46219026093375	0.940887883872574
GO:0004715	non-membrane spanning protein tyrosine kinase activity	6/2246	45/18639	0.133333333333333	1.10650044523598	0.462427064946404	0.940887883872574
GO:0019783	ubiquitin-like protein peptidase activity	16/2246	127/18639	0.125984251968504	1.04551223171903	0.464953544079597	0.940887883872574
GO:0022829	wide pore channel activity	5/2246	37/18639	0.135135135135135	1.12145315395538	0.465617605266623	0.940887883872574
GO:0043394	proteoglycan binding	5/2246	37/18639	0.135135135135135	1.12145315395538	0.465617605266623	0.940887883872574
GO:0016417	S-acyltransferase activity	4/2246	29/18639	0.137931034482759	1.14465563300273	0.469048888536311	0.940887883872574
GO:0051861	glycolipid binding	4/2246	29/18639	0.137931034482759	1.14465563300273	0.469048888536311	0.940887883872574
GO:0019955	cytokine binding	18/2246	144/18639	0.125	1.03734416740873	0.472029866952933	0.940887883872574
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/2246	21/18639	0.142857142857143	1.18553619132426	0.472690509424031	0.940887883872574
GO:0015174	basic amino acid transmembrane transporter activity	3/2246	21/18639	0.142857142857143	1.18553619132426	0.472690509424031	0.940887883872574
GO:0035613	RNA stem-loop binding	3/2246	21/18639	0.142857142857143	1.18553619132426	0.472690509424031	0.940887883872574
GO:0140312	cargo adaptor activity	3/2246	21/18639	0.142857142857143	1.18553619132426	0.472690509424031	0.940887883872574
GO:0016779	nucleotidyltransferase activity	17/2246	136/18639	0.125	1.03734416740873	0.474984928090717	0.940887883872574
GO:0015179	L-amino acid transmembrane transporter activity	8/2246	62/18639	0.129032258064516	1.07080688248643	0.475588776095639	0.940887883872574
GO:0003964	RNA-directed DNA polymerase activity	2/2246	13/18639	0.153846153846154	1.27673128296459	0.476108857791738	0.940887883872574
GO:0008253	5'-nucleotidase activity	2/2246	13/18639	0.153846153846154	1.27673128296459	0.476108857791738	0.940887883872574
GO:0015651	quaternary ammonium group transmembrane transporter activity	2/2246	13/18639	0.153846153846154	1.27673128296459	0.476108857791738	0.940887883872574
GO:0039706	co-receptor binding	2/2246	13/18639	0.153846153846154	1.27673128296459	0.476108857791738	0.940887883872574
GO:0046974	histone H3K9 methyltransferase activity	2/2246	13/18639	0.153846153846154	1.27673128296459	0.476108857791738	0.940887883872574
GO:0071714	icosanoid transmembrane transporter activity	2/2246	13/18639	0.153846153846154	1.27673128296459	0.476108857791738	0.940887883872574
GO:0071837	HMG box domain binding	2/2246	13/18639	0.153846153846154	1.27673128296459	0.476108857791738	0.940887883872574
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/2246	13/18639	0.153846153846154	1.27673128296459	0.476108857791738	0.940887883872574
GO:1901338	catecholamine binding	2/2246	13/18639	0.153846153846154	1.27673128296459	0.476108857791738	0.940887883872574
GO:0004867	serine-type endopeptidase inhibitor activity	12/2246	95/18639	0.126315789473684	1.04826357969724	0.477453868223417	0.940887883872574
GO:0008276	protein methyltransferase activity	12/2246	95/18639	0.126315789473684	1.04826357969724	0.477453868223417	0.940887883872574
GO:0046332	SMAD binding	10/2246	79/18639	0.126582278481013	1.05047510623669	0.485123979275026	0.954445874534579
GO:1901682	sulfur compound transmembrane transporter activity	8/2246	63/18639	0.126984126984127	1.05380994784379	0.494356166794438	0.971028047947449
GO:0033612	receptor serine/threonine kinase binding	4/2246	30/18639	0.133333333333333	1.10650044523598	0.496415077738773	0.971911529835394
GO:0048019	receptor antagonist activity	4/2246	30/18639	0.133333333333333	1.10650044523598	0.496415077738773	0.971911529835394
GO:0046943	carboxylic acid transmembrane transporter activity	23/2246	188/18639	0.122340425531915	1.01527301491067	0.502630869852587	0.982488820035477
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	16/2246	130/18639	0.123076923076923	1.02138502637167	0.504223800511617	0.984010260126063
GO:0140101	catalytic activity, acting on a tRNA	17/2246	139/18639	0.122302158273381	1.01495544437113	0.512935682166664	0.992057160523999
GO:0005342	organic acid transmembrane transporter activity	23/2246	189/18639	0.121693121693122	1.00990120001696	0.513434400405251	0.992057160523999
GO:0005347	ATP transmembrane transporter activity	2/2246	14/18639	0.142857142857143	1.18553619132426	0.516559564544367	0.992057160523999
GO:0008392	arachidonate epoxygenase activity	2/2246	14/18639	0.142857142857143	1.18553619132426	0.516559564544367	0.992057160523999
GO:0008559	ABC-type xenobiotic transporter activity	2/2246	14/18639	0.142857142857143	1.18553619132426	0.516559564544367	0.992057160523999
GO:0031404	chloride ion binding	2/2246	14/18639	0.142857142857143	1.18553619132426	0.516559564544367	0.992057160523999
GO:0034236	protein kinase A catalytic subunit binding	2/2246	14/18639	0.142857142857143	1.18553619132426	0.516559564544367	0.992057160523999
GO:0071933	Arp2/3 complex binding	2/2246	14/18639	0.142857142857143	1.18553619132426	0.516559564544367	0.992057160523999
GO:1901474	azole transmembrane transporter activity	2/2246	14/18639	0.142857142857143	1.18553619132426	0.516559564544367	0.992057160523999
GO:1901612	cardiolipin binding	2/2246	14/18639	0.142857142857143	1.18553619132426	0.516559564544367	0.992057160523999
GO:0008013	beta-catenin binding	13/2246	106/18639	0.122641509433962	1.01777163594818	0.517524815462287	0.99233329694991
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/2246	31/18639	0.129032258064516	1.07080688248643	0.523158554233224	0.99714461170278
GO:0016878	acid-thiol ligase activity	4/2246	31/18639	0.129032258064516	1.07080688248643	0.523158554233224	0.99714461170278
GO:0017147	Wnt-protein binding	4/2246	31/18639	0.129032258064516	1.07080688248643	0.523158554233224	0.99714461170278
GO:0051020	GTPase binding	38/2246	315/18639	0.120634920634921	1.0011194504516	0.523335830976459	0.99714461170278
GO:0004713	protein tyrosine kinase activity	17/2246	140/18639	0.121428571428571	1.00770576262562	0.525448436212251	0.998937395270461
GO:0000295	adenine nucleotide transmembrane transporter activity	3/2246	23/18639	0.130434782608696	1.08244608773085	0.535763284376207	0.998937395270461
GO:0003887	DNA-directed DNA polymerase activity	3/2246	23/18639	0.130434782608696	1.08244608773085	0.535763284376207	0.998937395270461
GO:0005212	structural constituent of eye lens	3/2246	23/18639	0.130434782608696	1.08244608773085	0.535763284376207	0.998937395270461
GO:0005283	amino acid:sodium symporter activity	3/2246	23/18639	0.130434782608696	1.08244608773085	0.535763284376207	0.998937395270461
GO:0031681	G-protein beta-subunit binding	3/2246	23/18639	0.130434782608696	1.08244608773085	0.535763284376207	0.998937395270461
GO:0030331	nuclear estrogen receptor binding	5/2246	40/18639	0.125	1.03734416740873	0.537117136605185	0.998937395270461
GO:0050997	quaternary ammonium group binding	5/2246	40/18639	0.125	1.03734416740873	0.537117136605185	0.998937395270461
GO:0071949	FAD binding	5/2246	40/18639	0.125	1.03734416740873	0.537117136605185	0.998937395270461
GO:0035064	methylated histone binding	9/2246	74/18639	0.121621621621622	1.00930783855984	0.54147285018181	0.998937395270461
GO:0001222	transcription corepressor binding	6/2246	49/18639	0.122448979591837	1.01617387827794	0.548573776444351	0.998937395270461
GO:0005004	GPI-linked ephrin receptor activity	6/2246	49/18639	0.122448979591837	1.01617387827794	0.548573776444351	0.998937395270461
GO:0005008	hepatocyte growth factor receptor activity	6/2246	49/18639	0.122448979591837	1.01617387827794	0.548573776444351	0.998937395270461
GO:0005009	insulin receptor activity	6/2246	49/18639	0.122448979591837	1.01617387827794	0.548573776444351	0.998937395270461
GO:0005011	macrophage colony-stimulating factor receptor activity	6/2246	49/18639	0.122448979591837	1.01617387827794	0.548573776444351	0.998937395270461
GO:0005018	platelet-derived growth factor alpha-receptor activity	6/2246	49/18639	0.122448979591837	1.01617387827794	0.548573776444351	0.998937395270461
GO:0005020	stem cell factor receptor activity	6/2246	49/18639	0.122448979591837	1.01617387827794	0.548573776444351	0.998937395270461
GO:0008288	boss receptor activity	6/2246	49/18639	0.122448979591837	1.01617387827794	0.548573776444351	0.998937395270461
GO:0036332	placental growth factor receptor activity	6/2246	49/18639	0.122448979591837	1.01617387827794	0.548573776444351	0.998937395270461
GO:0038062	protein tyrosine kinase collagen receptor activity	6/2246	49/18639	0.122448979591837	1.01617387827794	0.548573776444351	0.998937395270461
GO:0060175	brain-derived neurotrophic factor receptor activity	6/2246	49/18639	0.122448979591837	1.01617387827794	0.548573776444351	0.998937395270461
GO:1990782	protein tyrosine kinase binding	14/2246	117/18639	0.11965811965812	0.993013220083567	0.553802891531881	0.998937395270461
GO:0004089	carbonate dehydratase activity	2/2246	15/18639	0.133333333333333	1.10650044523598	0.554873337935827	0.998937395270461
GO:0004559	alpha-mannosidase activity	2/2246	15/18639	0.133333333333333	1.10650044523598	0.554873337935827	0.998937395270461
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/2246	15/18639	0.133333333333333	1.10650044523598	0.554873337935827	0.998937395270461
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/2246	15/18639	0.133333333333333	1.10650044523598	0.554873337935827	0.998937395270461
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/2246	15/18639	0.133333333333333	1.10650044523598	0.554873337935827	0.998937395270461
GO:0004953	icosanoid receptor activity	2/2246	15/18639	0.133333333333333	1.10650044523598	0.554873337935827	0.998937395270461
GO:0005041	low-density lipoprotein particle receptor activity	2/2246	15/18639	0.133333333333333	1.10650044523598	0.554873337935827	0.998937395270461
GO:0008242	omega peptidase activity	2/2246	15/18639	0.133333333333333	1.10650044523598	0.554873337935827	0.998937395270461
GO:0008252	nucleotidase activity	2/2246	15/18639	0.133333333333333	1.10650044523598	0.554873337935827	0.998937395270461
GO:0010181	FMN binding	2/2246	15/18639	0.133333333333333	1.10650044523598	0.554873337935827	0.998937395270461
GO:0033130	acetylcholine receptor binding	2/2246	15/18639	0.133333333333333	1.10650044523598	0.554873337935827	0.998937395270461
GO:0042809	nuclear vitamin D receptor binding	2/2246	15/18639	0.133333333333333	1.10650044523598	0.554873337935827	0.998937395270461
GO:0050780	dopamine receptor binding	2/2246	15/18639	0.133333333333333	1.10650044523598	0.554873337935827	0.998937395270461
GO:0141050	histone H3K deacetylase activity	2/2246	15/18639	0.133333333333333	1.10650044523598	0.554873337935827	0.998937395270461
GO:0141051	histone H4K deacetylase activity	2/2246	15/18639	0.133333333333333	1.10650044523598	0.554873337935827	0.998937395270461
GO:0017080	sodium channel regulator activity	5/2246	41/18639	0.121951219512195	1.01204309015486	0.559962971100127	0.999999999995683
GO:0099106	ion channel regulator activity	19/2246	160/18639	0.11875	0.98547695903829	0.563769146472989	0.999999999995683
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	3/2246	24/18639	0.125	1.03734416740873	0.565639246105517	0.999999999995683
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	3/2246	24/18639	0.125	1.03734416740873	0.565639246105517	0.999999999995683
GO:0015295	solute:proton symporter activity	3/2246	24/18639	0.125	1.03734416740873	0.565639246105517	0.999999999995683
GO:0035035	histone acetyltransferase binding	3/2246	24/18639	0.125	1.03734416740873	0.565639246105517	0.999999999995683
GO:0042625	ATPase-coupled ion transmembrane transporter activity	3/2246	24/18639	0.125	1.03734416740873	0.565639246105517	0.999999999995683
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	3/2246	24/18639	0.125	1.03734416740873	0.565639246105517	0.999999999995683
GO:0046961	proton-transporting ATPase activity, rotational mechanism	3/2246	24/18639	0.125	1.03734416740873	0.565639246105517	0.999999999995683
GO:0008173	RNA methyltransferase activity	8/2246	67/18639	0.119402985074627	0.990895921106843	0.567121795021038	0.999999999995683
GO:0005017	platelet-derived growth factor receptor activity	6/2246	50/18639	0.12	0.995850400712378	0.569142378053715	0.999999999995683
GO:0005019	platelet-derived growth factor beta-receptor activity	6/2246	50/18639	0.12	0.995850400712378	0.569142378053715	0.999999999995683
GO:0032813	tumor necrosis factor receptor superfamily binding	6/2246	50/18639	0.12	0.995850400712378	0.569142378053715	0.999999999995683
GO:0051213	dioxygenase activity	11/2246	93/18639	0.118279569892473	0.981572975612559	0.574019850949985	0.999999999995683
GO:0019903	protein phosphatase binding	17/2246	144/18639	0.118055555555556	0.97971393588602	0.574517142047556	0.999999999995683
GO:0140034	methylation-dependent protein binding	9/2246	76/18639	0.118421052631579	0.982747105966162	0.574979490664274	0.999999999995683
GO:0015459	potassium channel regulator activity	7/2246	59/18639	0.11864406779661	0.984597853811673	0.577254162834662	0.999999999995683
GO:0031593	polyubiquitin modification-dependent protein binding	7/2246	59/18639	0.11864406779661	0.984597853811673	0.577254162834662	0.999999999995683
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	27/2246	229/18639	0.117903930131004	0.978455633887707	0.578974552351159	0.999999999995683
GO:0051879	Hsp90 protein binding	5/2246	42/18639	0.119047619047619	0.987946826103549	0.582228169491386	0.999999999995683
GO:0003924	GTPase activity	39/2246	331/18639	0.117824773413897	0.977798731817289	0.58557819015888	0.999999999995683
GO:0016410	N-acyltransferase activity	11/2246	94/18639	0.117021276595745	0.971130709914553	0.588840639988281	0.999999999995683
GO:0005010	insulin-like growth factor receptor activity	6/2246	51/18639	0.117647058823529	0.976323922267037	0.589242441275781	0.999999999995683
GO:0005021	vascular endothelial growth factor receptor activity	6/2246	51/18639	0.117647058823529	0.976323922267037	0.589242441275781	0.999999999995683
GO:0005030	neurotrophin receptor activity	6/2246	51/18639	0.117647058823529	0.976323922267037	0.589242441275781	0.999999999995683
GO:0016597	amino acid binding	6/2246	51/18639	0.117647058823529	0.976323922267037	0.589242441275781	0.999999999995683
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/2246	16/18639	0.125	1.03734416740873	0.590977650812767	0.999999999995683
GO:0005324	long-chain fatty acid transmembrane transporter activity	2/2246	16/18639	0.125	1.03734416740873	0.590977650812767	0.999999999995683
GO:0008391	arachidonate monooxygenase activity	2/2246	16/18639	0.125	1.03734416740873	0.590977650812767	0.999999999995683
GO:0015378	sodium:chloride symporter activity	2/2246	16/18639	0.125	1.03734416740873	0.590977650812767	0.999999999995683
GO:0015923	mannosidase activity	2/2246	16/18639	0.125	1.03734416740873	0.590977650812767	0.999999999995683
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/2246	16/18639	0.125	1.03734416740873	0.590977650812767	0.999999999995683
GO:0016722	oxidoreductase activity, acting on metal ions	2/2246	16/18639	0.125	1.03734416740873	0.590977650812767	0.999999999995683
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/2246	16/18639	0.125	1.03734416740873	0.590977650812767	0.999999999995683
GO:0140328	floppase activity	2/2246	16/18639	0.125	1.03734416740873	0.590977650812767	0.999999999995683
GO:0000030	mannosyltransferase activity	3/2246	25/18639	0.12	0.995850400712378	0.594304061602243	0.999999999995683
GO:0008139	nuclear localization sequence binding	3/2246	25/18639	0.12	0.995850400712378	0.594304061602243	0.999999999995683
GO:0015645	fatty acid ligase activity	3/2246	25/18639	0.12	0.995850400712378	0.594304061602243	0.999999999995683
GO:0015662	P-type ion transporter activity	3/2246	25/18639	0.12	0.995850400712378	0.594304061602243	0.999999999995683
GO:0042974	nuclear retinoic acid receptor binding	3/2246	25/18639	0.12	0.995850400712378	0.594304061602243	0.999999999995683
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	3/2246	25/18639	0.12	0.995850400712378	0.594304061602243	0.999999999995683
GO:0120515	fatty acid-CoA ligase activity	3/2246	25/18639	0.12	0.995850400712378	0.594304061602243	0.999999999995683
GO:0140358	P-type transmembrane transporter activity	3/2246	25/18639	0.12	0.995850400712378	0.594304061602243	0.999999999995683
GO:0008175	tRNA methyltransferase activity	4/2246	34/18639	0.117647058823529	0.976323922267037	0.598923264672525	0.999999999995683
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	4/2246	34/18639	0.117647058823529	0.976323922267037	0.598923264672525	0.999999999995683
GO:0140030	modification-dependent protein binding	20/2246	173/18639	0.115606936416185	0.959393449626568	0.613770672153737	0.999999999995683
GO:0001637	G protein-coupled chemoattractant receptor activity	3/2246	26/18639	0.115384615384615	0.95754846222344	0.621706980308646	0.999999999995683
GO:0004112	cyclic-nucleotide phosphodiesterase activity	3/2246	26/18639	0.115384615384615	0.95754846222344	0.621706980308646	0.999999999995683
GO:0004950	chemokine receptor activity	3/2246	26/18639	0.115384615384615	0.95754846222344	0.621706980308646	0.999999999995683
GO:0005160	transforming growth factor beta receptor binding	3/2246	26/18639	0.115384615384615	0.95754846222344	0.621706980308646	0.999999999995683
GO:0015216	purine nucleotide transmembrane transporter activity	3/2246	26/18639	0.115384615384615	0.95754846222344	0.621706980308646	0.999999999995683
GO:0034237	protein kinase A regulatory subunit binding	3/2246	26/18639	0.115384615384615	0.95754846222344	0.621706980308646	0.999999999995683
GO:0050750	low-density lipoprotein particle receptor binding	3/2246	26/18639	0.115384615384615	0.95754846222344	0.621706980308646	0.999999999995683
GO:0070006	metalloaminopeptidase activity	3/2246	26/18639	0.115384615384615	0.95754846222344	0.621706980308646	0.999999999995683
GO:0005343	organic acid:sodium symporter activity	4/2246	35/18639	0.114285714285714	0.948428953059407	0.622508250809324	0.999999999995683
GO:0034061	DNA polymerase activity	4/2246	35/18639	0.114285714285714	0.948428953059407	0.622508250809324	0.999999999995683
GO:0140566	histone reader activity	4/2246	35/18639	0.114285714285714	0.948428953059407	0.622508250809324	0.999999999995683
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/2246	17/18639	0.117647058823529	0.976323922267037	0.624848458057509	0.999999999995683
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/2246	17/18639	0.117647058823529	0.976323922267037	0.624848458057509	0.999999999995683
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/2246	17/18639	0.117647058823529	0.976323922267037	0.624848458057509	0.999999999995683
GO:0019198	transmembrane receptor protein phosphatase activity	2/2246	17/18639	0.117647058823529	0.976323922267037	0.624848458057509	0.999999999995683
GO:0036041	long-chain fatty acid binding	2/2246	17/18639	0.117647058823529	0.976323922267037	0.624848458057509	0.999999999995683
GO:0038191	neuropilin binding	2/2246	17/18639	0.117647058823529	0.976323922267037	0.624848458057509	0.999999999995683
GO:0046965	nuclear retinoid X receptor binding	2/2246	17/18639	0.117647058823529	0.976323922267037	0.624848458057509	0.999999999995683
GO:0070403	NAD+ binding	2/2246	17/18639	0.117647058823529	0.976323922267037	0.624848458057509	0.999999999995683
GO:0043014	alpha-tubulin binding	5/2246	44/18639	0.113636363636364	0.943040152189751	0.624859148888109	0.999999999995683
GO:0005003	ephrin receptor activity	6/2246	53/18639	0.113207547169811	0.939481510106017	0.627912904689301	0.999999999995683
GO:0005005	transmembrane-ephrin receptor activity	6/2246	53/18639	0.113207547169811	0.939481510106017	0.627912904689301	0.999999999995683
GO:0016251	RNA polymerase II general transcription initiation factor activity	6/2246	53/18639	0.113207547169811	0.939481510106017	0.627912904689301	0.999999999995683
GO:0034212	protein N-acetyltransferase activity	6/2246	53/18639	0.113207547169811	0.939481510106017	0.627912904689301	0.999999999995683
GO:0038064	collagen receptor activity	6/2246	53/18639	0.113207547169811	0.939481510106017	0.627912904689301	0.999999999995683
GO:0051018	protein kinase A binding	6/2246	53/18639	0.113207547169811	0.939481510106017	0.627912904689301	0.999999999995683
GO:0046915	transition metal ion transmembrane transporter activity	5/2246	45/18639	0.111111111111111	0.922083704363313	0.645163159380822	0.999999999995683
GO:0140303	intramembrane lipid transporter activity	5/2246	45/18639	0.111111111111111	0.922083704363313	0.645163159380822	0.999999999995683
GO:0008170	N-methyltransferase activity	11/2246	98/18639	0.112244897959184	0.931492721754775	0.645642151776504	0.999999999995683
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	6/2246	54/18639	0.111111111111111	0.922083704363313	0.646432699749044	0.999999999995683
GO:0005044	scavenger receptor activity	3/2246	27/18639	0.111111111111111	0.922083704363313	0.647816039970843	0.999999999995683
GO:0016405	CoA-ligase activity	3/2246	27/18639	0.111111111111111	0.922083704363313	0.647816039970843	0.999999999995683
GO:0000900	mRNA regulatory element binding translation repressor activity	2/2246	18/18639	0.111111111111111	0.922083704363313	0.656499574270605	0.999999999995683
GO:0015172	acidic amino acid transmembrane transporter activity	2/2246	18/18639	0.111111111111111	0.922083704363313	0.656499574270605	0.999999999995683
GO:0015373	monoatomic anion:sodium symporter activity	2/2246	18/18639	0.111111111111111	0.922083704363313	0.656499574270605	0.999999999995683
GO:0016854	racemase and epimerase activity	2/2246	18/18639	0.111111111111111	0.922083704363313	0.656499574270605	0.999999999995683
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/2246	18/18639	0.111111111111111	0.922083704363313	0.656499574270605	0.999999999995683
GO:0030228	lipoprotein particle receptor activity	2/2246	18/18639	0.111111111111111	0.922083704363313	0.656499574270605	0.999999999995683
GO:1901611	phosphatidylglycerol binding	2/2246	18/18639	0.111111111111111	0.922083704363313	0.656499574270605	0.999999999995683
GO:0004843	cysteine-type deubiquitinase activity	12/2246	108/18639	0.111111111111111	0.922083704363313	0.662086352607378	0.999999999995683
GO:0030414	peptidase inhibitor activity	19/2246	169/18639	0.112426035502959	0.932995937551044	0.662121911323949	0.999999999995683
GO:0023023	MHC protein complex binding	4/2246	37/18639	0.108108108108108	0.897162523164304	0.666962629272867	0.999999999995683
GO:0030551	cyclic nucleotide binding	4/2246	37/18639	0.108108108108108	0.897162523164304	0.666962629272867	0.999999999995683
GO:0042805	actinin binding	4/2246	37/18639	0.108108108108108	0.897162523164304	0.666962629272867	0.999999999995683
GO:0051019	mitogen-activated protein kinase binding	3/2246	28/18639	0.107142857142857	0.889152143493194	0.672615606563328	0.999999999995683
GO:0051393	alpha-actinin binding	3/2246	28/18639	0.107142857142857	0.889152143493194	0.672615606563328	0.999999999995683
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	3/2246	28/18639	0.107142857142857	0.889152143493194	0.672615606563328	0.999999999995683
GO:0004519	endonuclease activity	14/2246	127/18639	0.110236220472441	0.914823202754153	0.67961157187773	0.999999999995683
GO:0001540	amyloid-beta binding	9/2246	83/18639	0.108433734939759	0.899864819920823	0.682432676462356	0.999999999995683
GO:0001784	phosphotyrosine residue binding	5/2246	47/18639	0.106382978723404	0.882846099922321	0.683640606834101	0.999999999995683
GO:0034987	immunoglobulin receptor binding	2/2246	19/18639	0.105263157894737	0.873552983081033	0.685973905730638	0.999999999995683
GO:0042800	histone H3K4 methyltransferase activity	2/2246	19/18639	0.105263157894737	0.873552983081033	0.685973905730638	0.999999999995683
GO:0043395	heparan sulfate proteoglycan binding	2/2246	19/18639	0.105263157894737	0.873552983081033	0.685973905730638	0.999999999995683
GO:0046624	sphingolipid transporter activity	2/2246	19/18639	0.105263157894737	0.873552983081033	0.685973905730638	0.999999999995683
GO:0120227	acyl-CoA binding	2/2246	19/18639	0.105263157894737	0.873552983081033	0.685973905730638	0.999999999995683
GO:1990380	K48-linked deubiquitinase activity	2/2246	19/18639	0.105263157894737	0.873552983081033	0.685973905730638	0.999999999995683
GO:0005109	frizzled binding	4/2246	38/18639	0.105263157894737	0.873552983081033	0.68779533285782	0.999999999995683
GO:0042887	amide transmembrane transporter activity	4/2246	38/18639	0.105263157894737	0.873552983081033	0.68779533285782	0.999999999995683
GO:0005416	amino acid:monoatomic cation symporter activity	3/2246	29/18639	0.103448275862069	0.85849172475205	0.696104074027984	0.999999999995683
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	3/2246	29/18639	0.103448275862069	0.85849172475205	0.696104074027984	0.999999999995683
GO:0015171	amino acid transmembrane transporter activity	11/2246	102/18639	0.107843137254902	0.894963595411451	0.697917579660726	0.999999999995683
GO:0016500	protein-hormone receptor activity	7/2246	67/18639	0.104477611940299	0.867033930968488	0.71198843007678	0.999999999995683
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	7/2246	67/18639	0.104477611940299	0.867033930968488	0.71198843007678	0.999999999995683
GO:0010851	cyclase regulator activity	2/2246	20/18639	0.1	0.829875333926981	0.713336244278796	0.999999999995683
GO:0016505	peptidase activator activity involved in apoptotic process	2/2246	20/18639	0.1	0.829875333926981	0.713336244278796	0.999999999995683
GO:0003730	mRNA 3'-UTR binding	29/2246	262/18639	0.110687022900763	0.918564300911544	0.71608406675804	0.999999999995683
GO:0001965	G-protein alpha-subunit binding	3/2246	30/18639	0.1	0.829875333926981	0.718291740282341	0.999999999995683
GO:0031210	phosphatidylcholine binding	3/2246	30/18639	0.1	0.829875333926981	0.718291740282341	0.999999999995683
GO:0004090	carbonyl reductase (NADPH) activity	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0004955	prostaglandin receptor activity	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0005381	iron ion transmembrane transporter activity	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0008401	retinoic acid 4-hydroxylase activity	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0008519	ammonium channel activity	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0015187	glycine transmembrane transporter activity	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0015643	toxic substance binding	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0016427	tRNA (cytidine) methyltransferase activity	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0031419	cobalamin binding	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0031434	mitogen-activated protein kinase kinase binding	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0032052	bile acid binding	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0035256	G protein-coupled glutamate receptor binding	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0042975	peroxisome proliferator activated receptor binding	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0043121	neurotrophin binding	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0043295	glutathione binding	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0099122	RNA polymerase II C-terminal domain binding	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0140999	histone H3K4 trimethyltransferase activity	1/2246	10/18639	0.1	0.829875333926981	0.723169079564833	0.999999999995683
GO:0005548	phospholipid transporter activity	7/2246	68/18639	0.102941176470588	0.854283431983657	0.72660831198305	0.999999999995683
GO:0030145	manganese ion binding	7/2246	68/18639	0.102941176470588	0.854283431983657	0.72660831198305	0.999999999995683
GO:0140223	general transcription initiation factor activity	7/2246	68/18639	0.102941176470588	0.854283431983657	0.72660831198305	0.999999999995683
GO:0036002	pre-mRNA binding	6/2246	59/18639	0.101694915254237	0.843941017552862	0.730239059255831	0.999999999995683
GO:0015605	organophosphate ester transmembrane transporter activity	5/2246	50/18639	0.1	0.829875333926981	0.735871550403106	0.999999999995683
GO:0019199	transmembrane receptor protein kinase activity	8/2246	78/18639	0.102564102564103	0.851154188643058	0.737692159477075	0.999999999995683
GO:0001846	opsonin binding	2/2246	21/18639	0.0952380952380952	0.790357460882839	0.738667374263508	0.999999999995683
GO:0008373	sialyltransferase activity	2/2246	21/18639	0.0952380952380952	0.790357460882839	0.738667374263508	0.999999999995683
GO:0009931	calcium-dependent protein serine/threonine kinase activity	2/2246	21/18639	0.0952380952380952	0.790357460882839	0.738667374263508	0.999999999995683
GO:0010314	phosphatidylinositol-5-phosphate binding	2/2246	21/18639	0.0952380952380952	0.790357460882839	0.738667374263508	0.999999999995683
GO:0051428	peptide hormone receptor binding	2/2246	21/18639	0.0952380952380952	0.790357460882839	0.738667374263508	0.999999999995683
GO:0047499	calcium-independent phospholipase A2 activity	3/2246	31/18639	0.0967741935483871	0.803105161864821	0.739198867359032	0.999999999995683
GO:0070325	lipoprotein particle receptor binding	3/2246	31/18639	0.0967741935483871	0.803105161864821	0.739198867359032	0.999999999995683
GO:0008080	N-acetyltransferase activity	7/2246	69/18639	0.101449275362319	0.841902512679546	0.740709807349514	0.999999999995683
GO:0016279	protein-lysine N-methyltransferase activity	7/2246	69/18639	0.101449275362319	0.841902512679546	0.740709807349514	0.999999999995683
GO:0001530	lipopolysaccharide binding	4/2246	41/18639	0.0975609756097561	0.809634472123884	0.744658849637432	0.999999999995683
GO:0042169	SH2 domain binding	4/2246	41/18639	0.0975609756097561	0.809634472123884	0.744658849637432	0.999999999995683
GO:0042287	MHC protein binding	4/2246	41/18639	0.0975609756097561	0.809634472123884	0.744658849637432	0.999999999995683
GO:0042578	phosphoric ester hydrolase activity	40/2246	363/18639	0.110192837465565	0.914463177880971	0.751793578606095	0.999999999995683
GO:0016278	lysine N-methyltransferase activity	7/2246	70/18639	0.1	0.829875333926981	0.754292146963032	0.999999999995683
GO:0004866	endopeptidase inhibitor activity	17/2246	161/18639	0.105590062111801	0.876265880544018	0.754832498198857	0.999999999995683
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0000099	sulfur amino acid transmembrane transporter activity	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0004954	prostanoid receptor activity	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0005114	type II transforming growth factor beta receptor binding	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0008046	axon guidance receptor activity	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0008172	S-methyltransferase activity	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0008271	secondary active sulfate transmembrane transporter activity	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0008432	JUN kinase binding	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0008503	benzodiazepine receptor activity	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0016594	glycine binding	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0031731	CCR6 chemokine receptor binding	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0034056	estrogen response element binding	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0042608	T cell receptor binding	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0043522	leucine zipper domain binding	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0070697	activin receptor binding	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0140537	transcription regulator activator activity	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:1900750	oligopeptide binding	1/2246	11/18639	0.0909090909090909	0.754432121751801	0.756545119464848	0.999999999995683
GO:0042626	ATPase-coupled transmembrane transporter activity	10/2246	98/18639	0.102040816326531	0.846811565231614	0.75772989232081	0.999999999995683
GO:0047498	calcium-dependent phospholipase A2 activity	3/2246	32/18639	0.09375	0.778008125556545	0.758853927053253	0.999999999995683
GO:0015026	coreceptor activity	6/2246	61/18639	0.0983606557377049	0.816270820256047	0.759529881892563	0.999999999995683
GO:0004407	histone deacetylase activity	2/2246	22/18639	0.0909090909090909	0.754432121751801	0.762059280939207	0.999999999995683
GO:0008093	cytoskeletal anchor activity	2/2246	22/18639	0.0909090909090909	0.754432121751801	0.762059280939207	0.999999999995683
GO:0015377	chloride:monoatomic cation symporter activity	2/2246	22/18639	0.0909090909090909	0.754432121751801	0.762059280939207	0.999999999995683
GO:0016881	acid-amino acid ligase activity	2/2246	22/18639	0.0909090909090909	0.754432121751801	0.762059280939207	0.999999999995683
GO:0031683	G-protein beta/gamma-subunit complex binding	2/2246	22/18639	0.0909090909090909	0.754432121751801	0.762059280939207	0.999999999995683
GO:0033558	protein lysine deacetylase activity	2/2246	22/18639	0.0909090909090909	0.754432121751801	0.762059280939207	0.999999999995683
GO:0140784	metal ion sensor activity	2/2246	22/18639	0.0909090909090909	0.754432121751801	0.762059280939207	0.999999999995683
GO:0005496	steroid binding	11/2246	108/18639	0.101851851851852	0.84524339566637	0.766842373769205	0.999999999995683
GO:0042826	histone deacetylase binding	13/2246	127/18639	0.102362204724409	0.849478688271713	0.774158938802449	0.999999999995683
GO:0030971	receptor tyrosine kinase binding	8/2246	81/18639	0.0987654320987654	0.819629959434055	0.775079391620637	0.999999999995683
GO:0001664	G protein-coupled receptor binding	32/2246	297/18639	0.107744107744108	0.894141773928061	0.776858370200908	0.999999999995683
GO:0071889	14-3-3 protein binding	3/2246	33/18639	0.0909090909090909	0.754432121751801	0.777292028661535	0.999999999995683
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/2246	23/18639	0.0869565217391304	0.721630725153897	0.783611280611874	0.999999999995683
GO:0005158	insulin receptor binding	2/2246	23/18639	0.0869565217391304	0.721630725153897	0.783611280611874	0.999999999995683
GO:0016493	C-C chemokine receptor activity	2/2246	23/18639	0.0869565217391304	0.721630725153897	0.783611280611874	0.999999999995683
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	2/2246	23/18639	0.0869565217391304	0.721630725153897	0.783611280611874	0.999999999995683
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	2/2246	23/18639	0.0869565217391304	0.721630725153897	0.783611280611874	0.999999999995683
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:0003720	telomerase activity	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:0003995	acyl-CoA dehydrogenase activity	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:0004000	adenosine deaminase activity	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:0004126	cytidine deaminase activity	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:0004875	complement receptor activity	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:0005165	neurotrophin receptor binding	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:0008179	adenylate cyclase binding	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:0010853	cyclase activator activity	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:0035259	nuclear glucocorticoid receptor binding	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:0097677	STAT family protein binding	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:1990459	transferrin receptor binding	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:1990817	poly(A) RNA polymerase activity	1/2246	12/18639	0.0833333333333333	0.691562778272484	0.785898762458297	0.999999999995683
GO:0004222	metalloendopeptidase activity	11/2246	110/18639	0.1	0.829875333926981	0.787194019546239	0.999999999995683
GO:0106310	protein serine kinase activity	39/2246	361/18639	0.10803324099723	0.896541219477902	0.790990058772392	0.999999999995683
GO:0043178	alcohol binding	9/2246	92/18639	0.0978260869565217	0.811834565798134	0.793320432142868	0.999999999995683
GO:0031267	small GTPase binding	30/2246	283/18639	0.106007067137809	0.879726502396093	0.799681561609672	0.999999999995683
GO:0015149	hexose transmembrane transporter activity	2/2246	24/18639	0.0833333333333333	0.691562778272484	0.803426920112452	0.999999999995683
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/2246	24/18639	0.0833333333333333	0.691562778272484	0.803426920112452	0.999999999995683
GO:0019957	C-C chemokine binding	2/2246	24/18639	0.0833333333333333	0.691562778272484	0.803426920112452	0.999999999995683
GO:0030215	semaphorin receptor binding	2/2246	24/18639	0.0833333333333333	0.691562778272484	0.803426920112452	0.999999999995683
GO:0055056	D-glucose transmembrane transporter activity	2/2246	24/18639	0.0833333333333333	0.691562778272484	0.803426920112452	0.999999999995683
GO:0070300	phosphatidic acid binding	2/2246	24/18639	0.0833333333333333	0.691562778272484	0.803426920112452	0.999999999995683
GO:0042605	peptide antigen binding	4/2246	45/18639	0.0888888888888889	0.73766696349065	0.807707672788171	0.999999999995683
GO:0004623	phospholipase A2 activity	3/2246	35/18639	0.0857142857142857	0.711321714794555	0.810682766120307	0.999999999995683
GO:0043015	gamma-tubulin binding	3/2246	35/18639	0.0857142857142857	0.711321714794555	0.810682766120307	0.999999999995683
GO:0004465	lipoprotein lipase activity	1/2246	13/18639	0.0769230769230769	0.638365641482293	0.811714587847176	0.999999999995683
GO:0004535	poly(A)-specific ribonuclease activity	1/2246	13/18639	0.0769230769230769	0.638365641482293	0.811714587847176	0.999999999995683
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/2246	13/18639	0.0769230769230769	0.638365641482293	0.811714587847176	0.999999999995683
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/2246	13/18639	0.0769230769230769	0.638365641482293	0.811714587847176	0.999999999995683
GO:0031432	titin binding	1/2246	13/18639	0.0769230769230769	0.638365641482293	0.811714587847176	0.999999999995683
GO:0035325	Toll-like receptor binding	1/2246	13/18639	0.0769230769230769	0.638365641482293	0.811714587847176	0.999999999995683
GO:0035673	oligopeptide transmembrane transporter activity	1/2246	13/18639	0.0769230769230769	0.638365641482293	0.811714587847176	0.999999999995683
GO:0045159	myosin II binding	1/2246	13/18639	0.0769230769230769	0.638365641482293	0.811714587847176	0.999999999995683
GO:0046975	histone H3K36 methyltransferase activity	1/2246	13/18639	0.0769230769230769	0.638365641482293	0.811714587847176	0.999999999995683
GO:0097157	pre-mRNA intronic binding	1/2246	13/18639	0.0769230769230769	0.638365641482293	0.811714587847176	0.999999999995683
GO:0140333	glycerophospholipid flippase activity	1/2246	13/18639	0.0769230769230769	0.638365641482293	0.811714587847176	0.999999999995683
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/2246	13/18639	0.0769230769230769	0.638365641482293	0.811714587847176	0.999999999995683
GO:0170055	lipid transmembrane transporter activity	5/2246	56/18639	0.0892857142857143	0.740960119577662	0.820798639738591	0.999999999995683
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	4/2246	46/18639	0.0869565217391304	0.721630725153897	0.821321526121489	0.999999999995683
GO:0001848	complement binding	2/2246	25/18639	0.08	0.663900267141585	0.821611516504643	0.999999999995683
GO:0015296	monoatomic anion:monoatomic cation symporter activity	2/2246	25/18639	0.08	0.663900267141585	0.821611516504643	0.999999999995683
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/2246	25/18639	0.08	0.663900267141585	0.821611516504643	0.999999999995683
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/2246	25/18639	0.08	0.663900267141585	0.821611516504643	0.999999999995683
GO:0019707	protein-cysteine S-acyltransferase activity	2/2246	25/18639	0.08	0.663900267141585	0.821611516504643	0.999999999995683
GO:0120020	cholesterol transfer activity	2/2246	25/18639	0.08	0.663900267141585	0.821611516504643	0.999999999995683
GO:0016409	palmitoyltransferase activity	3/2246	36/18639	0.0833333333333333	0.691562778272484	0.825727053981192	0.999999999995683
GO:0045505	dynein intermediate chain binding	3/2246	36/18639	0.0833333333333333	0.691562778272484	0.825727053981192	0.999999999995683
GO:0005125	cytokine activity	24/2246	234/18639	0.102564102564103	0.851154188643058	0.828271377377613	0.999999999995683
GO:0015932	nucleobase-containing compound transmembrane transporter activity	5/2246	57/18639	0.087719298245614	0.727960819234194	0.83255659687896	0.999999999995683
GO:0061733	protein-lysine-acetyltransferase activity	4/2246	47/18639	0.0851063829787234	0.706276879937856	0.83412905349706	0.999999999995683
GO:0005313	L-glutamate transmembrane transporter activity	1/2246	14/18639	0.0714285714285714	0.59276809566213	0.834418820408931	0.999999999995683
GO:0008174	mRNA methyltransferase activity	1/2246	14/18639	0.0714285714285714	0.59276809566213	0.834418820408931	0.999999999995683
GO:0008191	metalloendopeptidase inhibitor activity	1/2246	14/18639	0.0714285714285714	0.59276809566213	0.834418820408931	0.999999999995683
GO:0008195	phosphatidate phosphatase activity	1/2246	14/18639	0.0714285714285714	0.59276809566213	0.834418820408931	0.999999999995683
GO:0008331	high voltage-gated calcium channel activity	1/2246	14/18639	0.0714285714285714	0.59276809566213	0.834418820408931	0.999999999995683
GO:0008474	palmitoyl-(protein) hydrolase activity	1/2246	14/18639	0.0714285714285714	0.59276809566213	0.834418820408931	0.999999999995683
GO:0008494	translation activator activity	1/2246	14/18639	0.0714285714285714	0.59276809566213	0.834418820408931	0.999999999995683
GO:0015926	glucosidase activity	1/2246	14/18639	0.0714285714285714	0.59276809566213	0.834418820408931	0.999999999995683
GO:0032454	histone H3K9 demethylase activity	1/2246	14/18639	0.0714285714285714	0.59276809566213	0.834418820408931	0.999999999995683
GO:0042043	neurexin family protein binding	1/2246	14/18639	0.0714285714285714	0.59276809566213	0.834418820408931	0.999999999995683
GO:0042813	Wnt receptor activity	1/2246	14/18639	0.0714285714285714	0.59276809566213	0.834418820408931	0.999999999995683
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	1/2246	14/18639	0.0714285714285714	0.59276809566213	0.834418820408931	0.999999999995683
GO:0098599	palmitoyl hydrolase activity	1/2246	14/18639	0.0714285714285714	0.59276809566213	0.834418820408931	0.999999999995683
GO:0003724	RNA helicase activity	7/2246	77/18639	0.0909090909090909	0.754432121751801	0.835148256037083	0.999999999995683
GO:0004497	monooxygenase activity	10/2246	106/18639	0.0943396226415094	0.78290125842168	0.836338070000287	0.999999999995683
GO:0019902	phosphatase binding	19/2246	190/18639	0.1	0.829875333926981	0.837594810913351	0.999999999995683
GO:0008157	protein phosphatase 1 binding	2/2246	26/18639	0.0769230769230769	0.638365641482293	0.83827022785431	0.999999999995683
GO:0015145	monosaccharide transmembrane transporter activity	2/2246	26/18639	0.0769230769230769	0.638365641482293	0.83827022785431	0.999999999995683
GO:0030247	polysaccharide binding	2/2246	26/18639	0.0769230769230769	0.638365641482293	0.83827022785431	0.999999999995683
GO:0043548	phosphatidylinositol 3-kinase binding	2/2246	26/18639	0.0769230769230769	0.638365641482293	0.83827022785431	0.999999999995683
GO:0051139	metal cation:proton antiporter activity	2/2246	26/18639	0.0769230769230769	0.638365641482293	0.83827022785431	0.999999999995683
GO:0052742	phosphatidylinositol kinase activity	2/2246	26/18639	0.0769230769230769	0.638365641482293	0.83827022785431	0.999999999995683
GO:0070412	R-SMAD binding	2/2246	26/18639	0.0769230769230769	0.638365641482293	0.83827022785431	0.999999999995683
GO:0019213	deacetylase activity	3/2246	37/18639	0.0810810810810811	0.672871892373228	0.83973567969075	0.999999999995683
GO:0004674	protein serine/threonine kinase activity	46/2246	433/18639	0.106235565819861	0.881622756596793	0.840765615452069	0.999999999995683
GO:0015297	antiporter activity	13/2246	135/18639	0.0962962962962963	0.799139210448204	0.84163970785584	0.999999999995683
GO:0005501	retinoid binding	3/2246	38/18639	0.0789473684210526	0.655164737310775	0.852759137990715	0.999999999995683
GO:0019840	isoprenoid binding	3/2246	38/18639	0.0789473684210526	0.655164737310775	0.852759137990715	0.999999999995683
GO:0015293	symporter activity	14/2246	146/18639	0.0958904109589041	0.79577086814916	0.853008566571591	0.999999999995683
GO:0004683	calcium/calmodulin-dependent protein kinase activity	2/2246	27/18639	0.0740740740740741	0.614722469575542	0.853506562884987	0.999999999995683
GO:0008395	steroid hydroxylase activity	2/2246	27/18639	0.0740740740740741	0.614722469575542	0.853506562884987	0.999999999995683
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	2/2246	27/18639	0.0740740740740741	0.614722469575542	0.853506562884987	0.999999999995683
GO:0008186	ATP-dependent activity, acting on RNA	7/2246	79/18639	0.0886075949367089	0.73533257436568	0.853910011415542	0.999999999995683
GO:0008020	G protein-coupled photoreceptor activity	1/2246	15/18639	0.0666666666666667	0.553250222617988	0.854386354871296	0.999999999995683
GO:0015116	sulfate transmembrane transporter activity	1/2246	15/18639	0.0666666666666667	0.553250222617988	0.854386354871296	0.999999999995683
GO:0030553	cGMP binding	1/2246	15/18639	0.0666666666666667	0.553250222617988	0.854386354871296	0.999999999995683
GO:0045504	dynein heavy chain binding	1/2246	15/18639	0.0666666666666667	0.553250222617988	0.854386354871296	0.999999999995683
GO:0051371	muscle alpha-actinin binding	1/2246	15/18639	0.0666666666666667	0.553250222617988	0.854386354871296	0.999999999995683
GO:0120283	protein serine/threonine kinase binding	1/2246	15/18639	0.0666666666666667	0.553250222617988	0.854386354871296	0.999999999995683
GO:0008237	metallopeptidase activity	18/2246	184/18639	0.0978260869565217	0.811834565798134	0.857371821518504	0.999999999995683
GO:0019789	SUMO transferase activity	2/2246	28/18639	0.0714285714285714	0.59276809566213	0.867421251832807	0.999999999995683
GO:0045499	chemorepellent activity	2/2246	28/18639	0.0714285714285714	0.59276809566213	0.867421251832807	0.999999999995683
GO:0051119	sugar transmembrane transporter activity	2/2246	28/18639	0.0714285714285714	0.59276809566213	0.867421251832807	0.999999999995683
GO:0051959	dynein light intermediate chain binding	2/2246	28/18639	0.0714285714285714	0.59276809566213	0.867421251832807	0.999999999995683
GO:0141052	histone H3 demethylase activity	2/2246	28/18639	0.0714285714285714	0.59276809566213	0.867421251832807	0.999999999995683
GO:0030295	protein kinase activator activity	13/2246	139/18639	0.0935251798561151	0.776142398636745	0.869020005887107	0.999999999995683
GO:0000062	fatty-acyl-CoA binding	1/2246	16/18639	0.0625	0.518672083704363	0.871946935141864	0.999999999995683
GO:0004708	MAP kinase kinase activity	1/2246	16/18639	0.0625	0.518672083704363	0.871946935141864	0.999999999995683
GO:0015562	efflux transmembrane transporter activity	1/2246	16/18639	0.0625	0.518672083704363	0.871946935141864	0.999999999995683
GO:0140327	flippase activity	1/2246	16/18639	0.0625	0.518672083704363	0.871946935141864	0.999999999995683
GO:0004177	aminopeptidase activity	3/2246	40/18639	0.075	0.622406500445236	0.87605455396879	0.999999999995683
GO:0032451	demethylase activity	3/2246	40/18639	0.075	0.622406500445236	0.87605455396879	0.999999999995683
GO:0005319	lipid transporter activity	17/2246	178/18639	0.0955056179775281	0.792577566110038	0.876228406902754	0.999999999995683
GO:0052689	carboxylic ester hydrolase activity	8/2246	92/18639	0.0869565217391304	0.721630725153897	0.878892420473262	0.999999999995683
GO:0004629	phospholipase C activity	2/2246	29/18639	0.0689655172413793	0.572327816501366	0.880111413151683	0.999999999995683
GO:0005516	calmodulin binding	20/2246	207/18639	0.0966183574879227	0.801811916837663	0.881150225310302	0.999999999995683
GO:0005179	hormone activity	12/2246	132/18639	0.0909090909090909	0.754432121751801	0.884826175689212	0.999999999995683
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/2246	17/18639	0.0588235294117647	0.488161961133518	0.887390589959637	0.999999999995683
GO:0008569	minus-end-directed microtubule motor activity	1/2246	17/18639	0.0588235294117647	0.488161961133518	0.887390589959637	0.999999999995683
GO:0009881	photoreceptor activity	1/2246	17/18639	0.0588235294117647	0.488161961133518	0.887390589959637	0.999999999995683
GO:0015278	intracellularly gated calcium channel activity	1/2246	17/18639	0.0588235294117647	0.488161961133518	0.887390589959637	0.999999999995683
GO:0030169	low-density lipoprotein particle binding	1/2246	17/18639	0.0588235294117647	0.488161961133518	0.887390589959637	0.999999999995683
GO:0030548	acetylcholine receptor regulator activity	1/2246	17/18639	0.0588235294117647	0.488161961133518	0.887390589959637	0.999999999995683
GO:1901567	fatty acid derivative binding	1/2246	17/18639	0.0588235294117647	0.488161961133518	0.887390589959637	0.999999999995683
GO:0008083	growth factor activity	15/2246	162/18639	0.0925925925925926	0.768403086969427	0.891625042878524	0.999999999995683
GO:0031624	ubiquitin conjugating enzyme binding	2/2246	30/18639	0.0666666666666667	0.553250222617988	0.891669961213779	0.999999999995683
GO:0032452	histone demethylase activity	2/2246	30/18639	0.0666666666666667	0.553250222617988	0.891669961213779	0.999999999995683
GO:0051721	protein phosphatase 2A binding	2/2246	30/18639	0.0666666666666667	0.553250222617988	0.891669961213779	0.999999999995683
GO:0004402	histone acetyltransferase activity	3/2246	42/18639	0.0714285714285714	0.59276809566213	0.896017982361349	0.999999999995683
GO:0008525	phosphatidylcholine transporter activity	1/2246	18/18639	0.0555555555555556	0.461041852181656	0.900972414411933	0.999999999995683
GO:0034185	apolipoprotein binding	1/2246	18/18639	0.0555555555555556	0.461041852181656	0.900972414411933	0.999999999995683
GO:0099602	neurotransmitter receptor regulator activity	1/2246	18/18639	0.0555555555555556	0.461041852181656	0.900972414411933	0.999999999995683
GO:0005184	neuropeptide hormone activity	2/2246	31/18639	0.0645161290322581	0.535403441243214	0.90218520906583	0.999999999995683
GO:0140457	protein demethylase activity	2/2246	31/18639	0.0645161290322581	0.535403441243214	0.90218520906583	0.999999999995683
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	26/2246	268/18639	0.0970149253731343	0.80510293589931	0.903510809351881	0.999999999995683
GO:0035173	histone kinase activity	36/2246	360/18639	0.1	0.829875333926981	0.903768199699662	0.999999999995683
GO:0015294	solute:monoatomic cation symporter activity	10/2246	116/18639	0.0862068965517241	0.715409770626708	0.905008861512321	0.999999999995683
GO:0140375	immune receptor activity	14/2246	156/18639	0.0897435897435897	0.744759915062676	0.909151486137627	0.999999999995683
GO:0015106	bicarbonate transmembrane transporter activity	2/2246	32/18639	0.0625	0.518672083704363	0.911740627866669	0.999999999995683
GO:0071813	lipoprotein particle binding	2/2246	32/18639	0.0625	0.518672083704363	0.911740627866669	0.999999999995683
GO:0071814	protein-lipid complex binding	2/2246	32/18639	0.0625	0.518672083704363	0.911740627866669	0.999999999995683
GO:0120015	sterol transfer activity	2/2246	32/18639	0.0625	0.518672083704363	0.911740627866669	0.999999999995683
GO:0160041	neuropeptide activity	2/2246	32/18639	0.0625	0.518672083704363	0.911740627866669	0.999999999995683
GO:0004252	serine-type endopeptidase activity	16/2246	176/18639	0.0909090909090909	0.754432121751801	0.912264482554562	0.999999999995683
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/2246	19/18639	0.0526315789473684	0.436776491540516	0.912916776005338	0.999999999995683
GO:0016918	retinal binding	1/2246	19/18639	0.0526315789473684	0.436776491540516	0.912916776005338	0.999999999995683
GO:0022840	leak channel activity	1/2246	19/18639	0.0526315789473684	0.436776491540516	0.912916776005338	0.999999999995683
GO:0022842	narrow pore channel activity	1/2246	19/18639	0.0526315789473684	0.436776491540516	0.912916776005338	0.999999999995683
GO:0042577	lipid phosphatase activity	1/2246	19/18639	0.0526315789473684	0.436776491540516	0.912916776005338	0.999999999995683
GO:0042834	peptidoglycan binding	1/2246	19/18639	0.0526315789473684	0.436776491540516	0.912916776005338	0.999999999995683
GO:0019209	kinase activator activity	13/2246	148/18639	0.0878378378378378	0.728944550070997	0.916924526198132	0.999999999995683
GO:0008234	cysteine-type peptidase activity	17/2246	187/18639	0.0909090909090909	0.754432121751801	0.917909369392794	0.999999999995683
GO:0019239	deaminase activity	2/2246	33/18639	0.0606060606060606	0.502954747834534	0.920414731041193	0.999999999995683
GO:0001972	retinoic acid binding	1/2246	20/18639	0.05	0.414937666963491	0.923421014517261	0.999999999995683
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/2246	20/18639	0.05	0.414937666963491	0.923421014517261	0.999999999995683
GO:0015095	magnesium ion transmembrane transporter activity	1/2246	20/18639	0.05	0.414937666963491	0.923421014517261	0.999999999995683
GO:0052745	inositol phosphate phosphatase activity	1/2246	20/18639	0.05	0.414937666963491	0.923421014517261	0.999999999995683
GO:0016798	hydrolase activity, acting on glycosyl bonds	11/2246	130/18639	0.0846153846153846	0.702202205630523	0.924608023164798	0.999999999995683
GO:0008376	acetylgalactosaminyltransferase activity	2/2246	34/18639	0.0588235294117647	0.488161961133518	0.928281056609343	0.999999999995683
GO:0051427	hormone receptor binding	2/2246	34/18639	0.0588235294117647	0.488161961133518	0.928281056609343	0.999999999995683
GO:0005123	death receptor binding	1/2246	21/18639	0.0476190476190476	0.39517873044142	0.932658696529949	0.999999999995683
GO:0036122	BMP binding	1/2246	21/18639	0.0476190476190476	0.39517873044142	0.932658696529949	0.999999999995683
GO:0061891	calcium ion sensor activity	1/2246	21/18639	0.0476190476190476	0.39517873044142	0.932658696529949	0.999999999995683
GO:0140359	ABC-type transporter activity	3/2246	47/18639	0.0638297872340425	0.529707659953392	0.933852885335076	0.999999999995683
GO:0015291	secondary active transmembrane transporter activity	27/2246	287/18639	0.0940766550522648	0.780718955262317	0.934216533905268	0.999999999995683
GO:0001217	DNA-binding transcription repressor activity	26/2246	278/18639	0.0935251798561151	0.776142398636745	0.93534486866212	0.999999999995683
GO:0010485	histone H4 acetyltransferase activity	2/2246	35/18639	0.0571428571428571	0.474214476529704	0.935408225729891	0.999999999995683
GO:0004879	nuclear receptor activity	4/2246	59/18639	0.0677966101694915	0.562627345035242	0.936293699350626	0.999999999995683
GO:0141003	histone H2AX kinase activity	34/2246	354/18639	0.096045197740113	0.797055405466592	0.938072035819976	0.999999999995683
GO:0005253	monoatomic anion channel activity	8/2246	103/18639	0.0776699029126214	0.644563366156879	0.939578369460425	0.999999999995683
GO:0032266	phosphatidylinositol-3-phosphate binding	3/2246	48/18639	0.0625	0.518672083704363	0.939699073397037	0.999999999995683
GO:0038187	pattern recognition receptor activity	3/2246	48/18639	0.0625	0.518672083704363	0.939699073397037	0.999999999995683
GO:0140693	molecular condensate scaffold activity	3/2246	48/18639	0.0625	0.518672083704363	0.939699073397037	0.999999999995683
GO:0005243	gap junction channel activity	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0008970	phospholipase A1 activity	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0032931	histone H3K56 acetyltransferase activity	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0033691	sialic acid binding	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0043992	histone H3K9 acetyltransferase activity	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0043993	histone H3K18 acetyltransferase activity	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0043994	histone H3K23 acetyltransferase activity	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0043999	histone H2AK5 acetyltransferase activity	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0044012	histone H2AK9 acetyltransferase activity	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0044014	histone H2BK5 acetyltransferase activity	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0044015	histone H2BK12 acetyltransferase activity	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0044016	histone H3K4 acetyltransferase activity	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0044017	histone H3K27 acetyltransferase activity	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0044018	histone H3K36 acetyltransferase activity	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0046972	histone H4K16 acetyltransferase activity	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0050321	tau-protein kinase activity	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0140908	histone H3K122 acetyltransferase activity	1/2246	22/18639	0.0454545454545455	0.377216060875901	0.940782478224746	0.999999999995683
GO:0098531	ligand-modulated transcription factor activity	4/2246	60/18639	0.0666666666666667	0.553250222617988	0.941451191419174	0.999999999995683
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/2246	36/18639	0.0555555555555556	0.461041852181656	0.941860059362168	0.999999999995683
GO:0140996	histone H3 kinase activity	34/2246	357/18639	0.0952380952380952	0.790357460882839	0.944702426478305	0.999999999995683
GO:0030165	PDZ domain binding	6/2246	83/18639	0.072289156626506	0.599909879947215	0.944815087225856	0.999999999995683
GO:0035254	glutamate receptor binding	3/2246	49/18639	0.0612244897959184	0.508086939138968	0.94506343525162	0.999999999995683
GO:0017124	SH3 domain binding	9/2246	115/18639	0.0782608695652174	0.649467652638507	0.94550399017774	0.999999999995683
GO:0030280	structural constituent of skin epidermis	2/2246	37/18639	0.0540540540540541	0.448581261582152	0.947695738200534	0.999999999995683
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/2246	23/18639	0.0434782608695652	0.360815362576948	0.947926623570786	0.999999999995683
GO:0016849	phosphorus-oxygen lyase activity	1/2246	23/18639	0.0434782608695652	0.360815362576948	0.947926623570786	0.999999999995683
GO:0044013	histone H2B acetyltransferase activity	1/2246	23/18639	0.0434782608695652	0.360815362576948	0.947926623570786	0.999999999995683
GO:0070577	lysine-acetylated histone binding	1/2246	23/18639	0.0434782608695652	0.360815362576948	0.947926623570786	0.999999999995683
GO:0004622	lysophospholipase activity	1/2246	24/18639	0.0416666666666667	0.345781389136242	0.954209219373322	0.999999999995683
GO:0004806	triacylglycerol lipase activity	1/2246	24/18639	0.0416666666666667	0.345781389136242	0.954209219373322	0.999999999995683
GO:0005315	phosphate transmembrane transporter activity	1/2246	24/18639	0.0416666666666667	0.345781389136242	0.954209219373322	0.999999999995683
GO:0030552	cAMP binding	1/2246	24/18639	0.0416666666666667	0.345781389136242	0.954209219373322	0.999999999995683
GO:0043998	histone H2A acetyltransferase activity	1/2246	24/18639	0.0416666666666667	0.345781389136242	0.954209219373322	0.999999999995683
GO:0050431	transforming growth factor beta binding	1/2246	24/18639	0.0416666666666667	0.345781389136242	0.954209219373322	0.999999999995683
GO:0140033	acetylation-dependent protein binding	1/2246	24/18639	0.0416666666666667	0.345781389136242	0.954209219373322	0.999999999995683
GO:0008509	monoatomic anion transmembrane transporter activity	12/2246	149/18639	0.0805369127516778	0.668355973632468	0.955076930194447	0.999999999995683
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	6/2246	86/18639	0.0697674418604651	0.578982791111847	0.955943776989202	0.999999999995683
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	3/2246	52/18639	0.0576923076923077	0.47877423111172	0.958608648630028	0.999999999995683
GO:0030159	signaling receptor complex adaptor activity	3/2246	52/18639	0.0576923076923077	0.47877423111172	0.958608648630028	0.999999999995683
GO:0008081	phosphoric diester hydrolase activity	6/2246	87/18639	0.0689655172413793	0.572327816501366	0.959174904975661	0.999999999995683
GO:0047617	fatty acyl-CoA hydrolase activity	1/2246	25/18639	0.04	0.331950133570793	0.959734123659517	0.999999999995683
GO:0004620	phospholipase activity	8/2246	109/18639	0.073394495412844	0.609082813891362	0.959783883747667	0.999999999995683
GO:0160215	deacylase activity	4/2246	65/18639	0.0615384615384615	0.510692513185835	0.961960300474101	0.999999999995683
GO:0015144	carbohydrate transmembrane transporter activity	2/2246	40/18639	0.05	0.414937666963491	0.96203220330945	0.999999999995683
GO:0004197	cysteine-type endopeptidase activity	6/2246	88/18639	0.0681818181818182	0.565824091313851	0.962189132549058	0.999999999995683
GO:0017046	peptide hormone binding	3/2246	53/18639	0.0566037735849057	0.469740755053008	0.96237887950722	0.999999999995683
GO:1901505	carbohydrate derivative transmembrane transporter activity	3/2246	53/18639	0.0566037735849057	0.469740755053008	0.96237887950722	0.999999999995683
GO:0016289	acyl-CoA hydrolase activity	1/2246	26/18639	0.0384615384615385	0.319182820741147	0.964592679491725	0.999999999995683
GO:0019865	immunoglobulin binding	1/2246	26/18639	0.0384615384615385	0.319182820741147	0.964592679491725	0.999999999995683
GO:0030507	spectrin binding	1/2246	26/18639	0.0384615384615385	0.319182820741147	0.964592679491725	0.999999999995683
GO:0120014	phospholipid transfer activity	1/2246	26/18639	0.0384615384615385	0.319182820741147	0.964592679491725	0.999999999995683
GO:1902936	phosphatidylinositol bisphosphate binding	8/2246	111/18639	0.0720720720720721	0.598108348776203	0.965025740151712	0.999999999995683
GO:0008235	metalloexopeptidase activity	4/2246	66/18639	0.0606060606060606	0.502954747834534	0.965163391677364	0.999999999995683
GO:0008236	serine-type peptidase activity	16/2246	194/18639	0.0824742268041237	0.684433265094418	0.965256962551704	0.999999999995683
GO:0001727	lipid kinase activity	2/2246	41/18639	0.0487804878048781	0.404817236061942	0.965909347117751	0.999999999995683
GO:0004812	aminoacyl-tRNA ligase activity	2/2246	41/18639	0.0487804878048781	0.404817236061942	0.965909347117751	0.999999999995683
GO:0008227	G protein-coupled amine receptor activity	2/2246	41/18639	0.0487804878048781	0.404817236061942	0.965909347117751	0.999999999995683
GO:0016875	ligase activity, forming carbon-oxygen bonds	2/2246	41/18639	0.0487804878048781	0.404817236061942	0.965909347117751	0.999999999995683
GO:0140828	metal cation:monoatomic cation antiporter activity	2/2246	41/18639	0.0487804878048781	0.404817236061942	0.965909347117751	0.999999999995683
GO:0015370	solute:sodium symporter activity	5/2246	79/18639	0.0632911392405063	0.525237553118343	0.968701917919869	0.999999999995683
GO:0035255	ionotropic glutamate receptor binding	1/2246	27/18639	0.037037037037037	0.307361234787771	0.968865222438138	0.999999999995683
GO:0035402	histone H3T11 kinase activity	21/2246	247/18639	0.0850202429149798	0.705562024796219	0.970634667687371	0.999999999995683
GO:0016757	glycosyltransferase activity	23/2246	267/18639	0.0861423220973783	0.714873883158074	0.97108327078851	0.999999999995683
GO:0017171	serine hydrolase activity	16/2246	198/18639	0.0808080808080808	0.670606330446046	0.972167844633243	0.999999999995683
GO:0005245	voltage-gated calcium channel activity	2/2246	43/18639	0.0465116279069767	0.385988527407898	0.972551761552255	0.999999999995683
GO:0036408	histone H3K14 acetyltransferase activity	1/2246	28/18639	0.0357142857142857	0.296384047831065	0.972622406534632	0.999999999995683
GO:0016790	thiolester hydrolase activity	2/2246	44/18639	0.0454545454545455	0.377216060875901	0.975385658221471	0.999999999995683
GO:0016782	transferase activity, transferring sulphur-containing groups	4/2246	70/18639	0.0571428571428571	0.474214476529704	0.975624753888452	0.999999999995683
GO:0004181	metallocarboxypeptidase activity	1/2246	29/18639	0.0344827586206897	0.286163908250683	0.975926370584023	0.999999999995683
GO:0010484	histone H3 acetyltransferase activity	1/2246	29/18639	0.0344827586206897	0.286163908250683	0.975926370584023	0.999999999995683
GO:0035250	UDP-galactosyltransferase activity	1/2246	29/18639	0.0344827586206897	0.286163908250683	0.975926370584023	0.999999999995683
GO:0099604	ligand-gated calcium channel activity	1/2246	29/18639	0.0344827586206897	0.286163908250683	0.975926370584023	0.999999999995683
GO:0001653	peptide receptor activity	9/2246	128/18639	0.0703125	0.583506094167409	0.977290072646069	0.999999999995683
GO:0005254	chloride channel activity	5/2246	83/18639	0.0602409638554217	0.499924899956013	0.977627138811339	0.999999999995683
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	20/2246	243/18639	0.0823045267489712	0.683024966195046	0.978416133471747	0.999999999995683
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/2246	30/18639	0.0333333333333333	0.276625111308994	0.978831764010583	0.999999999995683
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/2246	30/18639	0.0333333333333333	0.276625111308994	0.978831764010583	0.999999999995683
GO:0043995	histone H4K5 acetyltransferase activity	1/2246	30/18639	0.0333333333333333	0.276625111308994	0.978831764010583	0.999999999995683
GO:0043996	histone H4K8 acetyltransferase activity	1/2246	30/18639	0.0333333333333333	0.276625111308994	0.978831764010583	0.999999999995683
GO:0043997	histone H4K12 acetyltransferase activity	1/2246	30/18639	0.0333333333333333	0.276625111308994	0.978831764010583	0.999999999995683
GO:0070566	adenylyltransferase activity	1/2246	30/18639	0.0333333333333333	0.276625111308994	0.978831764010583	0.999999999995683
GO:0035591	signaling adaptor activity	9/2246	129/18639	0.0697674418604651	0.578982791111847	0.978834088352946	0.999999999995683
GO:0030276	clathrin binding	2/2246	46/18639	0.0434782608695652	0.360815362576948	0.980228608589136	0.999999999995683
GO:0004676	3-phosphoinositide-dependent protein kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:0004711	ribosomal protein S6 kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:0035175	histone H3S10 kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:0035979	histone H2AXS139 kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:0044022	histone H3S28 kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:0044023	histone H4S1 kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:0044024	histone H2AS1 kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:0044025	histone H2BS14 kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:0072354	histone H3T3 kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:0072371	histone H2AS121 kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:0072518	Rho-dependent protein serine/threonine kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:0140823	histone H2BS36 kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:0140855	histone H3S57 kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:0140995	histone H2A kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:0140997	histone H4 kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:0140998	histone H2B kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:1990244	histone H2AT120 kinase activity	20/2246	245/18639	0.0816326530612245	0.677449252185291	0.980600361832594	0.999999999995683
GO:0005452	solute:inorganic anion antiporter activity	1/2246	31/18639	0.032258064516129	0.267701720621607	0.981386649175408	0.999999999995683
GO:0070273	phosphatidylinositol-4-phosphate binding	1/2246	31/18639	0.032258064516129	0.267701720621607	0.981386649175408	0.999999999995683
GO:0004677	DNA-dependent protein kinase activity	20/2246	246/18639	0.0813008130081301	0.67469539343657	0.981616087728164	0.999999999995683
GO:0140857	histone H3T45 kinase activity	20/2246	246/18639	0.0813008130081301	0.67469539343657	0.981616087728164	0.999999999995683
GO:1901981	phosphatidylinositol phosphate binding	14/2246	185/18639	0.0756756756756757	0.628013766215013	0.982195868344816	0.999999999995683
GO:0035403	histone H3T6 kinase activity	20/2246	247/18639	0.0809716599190283	0.671963833139256	0.982583613722947	0.999999999995683
GO:0019905	syntaxin binding	3/2246	61/18639	0.0491803278688525	0.408135410128024	0.982791485584921	0.999999999995683
GO:0004679	AMP-activated protein kinase activity	20/2246	248/18639	0.0806451612903226	0.669254301554017	0.983504907981373	0.999999999995683
GO:0008378	galactosyltransferase activity	1/2246	32/18639	0.03125	0.259336041852182	0.983633295024077	0.999999999995683
GO:0008188	neuropeptide receptor activity	2/2246	48/18639	0.0416666666666667	0.345781389136242	0.984141520473039	0.999999999995683
GO:0008528	G protein-coupled peptide receptor activity	8/2246	122/18639	0.0655737704918033	0.544180546837365	0.984291862544672	0.999999999995683
GO:0030296	protein tyrosine kinase activator activity	1/2246	33/18639	0.0303030303030303	0.251477373917267	0.985608875148542	0.999999999995683
GO:0015085	calcium ion transmembrane transporter activity	10/2246	147/18639	0.0680272108843537	0.564541043487742	0.987114142032125	0.999999999995683
GO:0015020	glucuronosyltransferase activity	1/2246	34/18639	0.0294117647058824	0.244080980566759	0.987346081770942	0.999999999995683
GO:0008238	exopeptidase activity	6/2246	102/18639	0.0588235294117647	0.488161961133518	0.987718447591281	0.999999999995683
GO:0120013	lipid transfer activity	3/2246	65/18639	0.0461538461538462	0.383019384889376	0.988484694593317	0.999999999995683
GO:0004175	endopeptidase activity	35/2246	405/18639	0.0864197530864197	0.717176214504799	0.989049950696478	0.999999999995683
GO:0004033	aldo-keto reductase (NADPH) activity	1/2246	36/18639	0.0277777777777778	0.230520926090828	0.990216911669578	0.999999999995683
GO:0004190	aspartic-type endopeptidase activity	1/2246	36/18639	0.0277777777777778	0.230520926090828	0.990216911669578	0.999999999995683
GO:0070001	aspartic-type peptidase activity	1/2246	37/18639	0.027027027027027	0.224290630791076	0.991398055377051	0.999999999995683
GO:0016298	lipase activity	8/2246	130/18639	0.0615384615384615	0.510692513185835	0.9914932131699	0.999999999995683
GO:0015103	inorganic anion transmembrane transporter activity	11/2246	165/18639	0.0666666666666667	0.553250222617988	0.992118525518924	0.999999999995683
GO:0005085	guanyl-nucleotide exchange factor activity	17/2246	230/18639	0.0739130434782609	0.613386116380812	0.992226998221981	0.999999999995683
GO:0008374	O-acyltransferase activity	2/2246	55/18639	0.0363636363636364	0.30177284870072	0.992743685246396	0.999999999995683
GO:0015108	chloride transmembrane transporter activity	7/2246	121/18639	0.0578512396694215	0.48009316838751	0.993174909455183	0.999999999995683
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	7/2246	122/18639	0.0573770491803279	0.476157978482694	0.993715616658431	0.999999999995683
GO:0071855	neuropeptide receptor binding	1/2246	40/18639	0.025	0.207468833481745	0.994152914975637	0.999999999995683
GO:0005096	GTPase activator activity	20/2246	271/18639	0.0738007380073801	0.612454120979322	0.995613297500202	0.999999999995683
GO:0030695	GTPase regulator activity	41/2246	489/18639	0.0838445807770961	0.695805494703604	0.996613636015512	0.999999999995683
GO:0060589	nucleoside-triphosphatase regulator activity	41/2246	490/18639	0.0836734693877551	0.694385483489923	0.996771563392678	0.999999999995683
GO:0005262	calcium channel activity	7/2246	131/18639	0.0534351145038168	0.443444834922814	0.997055583538146	0.999999999995683
GO:0000149	SNARE binding	5/2246	106/18639	0.0471698113207547	0.39145062921084	0.997152613495248	0.999999999995683
GO:0004180	carboxypeptidase activity	1/2246	46/18639	0.0217391304347826	0.180407681288474	0.997298914403791	0.999999999995683
GO:0140767	enzyme-substrate adaptor activity	7/2246	139/18639	0.0503597122302158	0.41792283003517	0.99853091179179	0.999999999995683
GO:0008146	sulfotransferase activity	1/2246	53/18639	0.0188679245283019	0.156580251684336	0.998903291804701	0.999999999995683
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	3/2246	91/18639	0.032967032967033	0.273585274920983	0.999254539578617	0.999999999995683
GO:0003823	antigen binding	9/2246	174/18639	0.0517241379310345	0.429245862376025	0.99937874438635	0.999999999995683
GO:0005543	phospholipid binding	38/2246	497/18639	0.0764587525150905	0.634512327751012	0.999527146744702	0.999999999995683
GO:0016758	hexosyltransferase activity	10/2246	197/18639	0.050761421319797	0.421256514683747	0.999746518900818	0.999999999995683
GO:0004842	ubiquitin-protein transferase activity	32/2246	449/18639	0.0712694877505568	0.591447899457982	0.999799092987856	0.999999999995683
GO:0035091	phosphatidylinositol binding	17/2246	284/18639	0.0598591549295775	0.4967563618577	0.999804348449452	0.999999999995683
GO:0019787	ubiquitin-like protein transferase activity	34/2246	479/18639	0.0709812108559499	0.589055560616229	0.999881766075907	0.999999999995683
GO:0016755	aminoacyltransferase activity	35/2246	496/18639	0.0705645161290323	0.585597513859765	0.999919726064835	0.999999999995683
GO:0008194	UDP-glycosyltransferase activity	5/2246	145/18639	0.0344827586206897	0.286163908250683	0.999939508746855	0.999999999995683
GO:0001216	DNA-binding transcription activator activity	34/2246	491/18639	0.0692464358452139	0.574659090703001	0.999943679573168	0.999999999995683
GO:0030527	structural constituent of chromatin	2/2246	98/18639	0.0204081632653061	0.169362313046323	0.999951976357938	0.999999999995683
GO:0015081	sodium ion transmembrane transporter activity	6/2246	164/18639	0.0365853658536585	0.303612927046457	0.999961265006761	0.999999999995683
GO:0061630	ubiquitin protein ligase activity	21/2246	353/18639	0.0594900849858357	0.493693541429649	0.999963622711274	0.999999999995683
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	32/2246	484/18639	0.0661157024793388	0.548677906728583	0.999978182922965	0.999999999995683
GO:0061659	ubiquitin-like protein ligase activity	21/2246	372/18639	0.0564516129032258	0.468478011087812	0.999991268427911	0.999999999995683
GO:0030594	neurotransmitter receptor activity	1/2246	97/18639	0.0103092783505155	0.0855541581368022	0.999996233336276	0.999999999995683
GO:0005244	voltage-gated monoatomic ion channel activity	5/2246	173/18639	0.0289017341040462	0.239848362406642	0.999996818103586	0.999999999995683
GO:0022832	voltage-gated channel activity	5/2246	175/18639	0.0285714285714286	0.237107238264852	0.999997432800466	0.999999999995683
GO:0099094	ligand-gated monoatomic cation channel activity	2/2246	136/18639	0.0147058823529412	0.12204049028338	0.999999518033113	0.999999999995683
GO:0022843	voltage-gated monoatomic cation channel activity	2/2246	143/18639	0.013986013986014	0.116066480269508	0.999999795620958	0.999999999995683
GO:0046873	metal ion transmembrane transporter activity	23/2246	450/18639	0.0511111111111111	0.424158504007124	0.999999877862359	0.999999999995683
GO:0005267	potassium channel activity	1/2246	124/18639	0.00806451612903226	0.0669254301554017	0.999999884977589	0.999999999995683
GO:0015079	potassium ion transmembrane transporter activity	2/2246	160/18639	0.0125	0.103734416740873	0.999999974813384	0.999999999995683
GO:0022834	ligand-gated channel activity	3/2246	188/18639	0.0159574468085106	0.132426914988348	0.999999989491858	0.999999999995683
GO:0045182	translation regulator activity	13/2246	356/18639	0.0365168539325843	0.303044363512662	0.999999995422742	0.999999999995683
GO:0015276	ligand-gated monoatomic ion channel activity	2/2246	186/18639	0.010752688172043	0.089233906873869	0.999999998999375	0.999999999995683
GO:0022836	gated channel activity	8/2246	318/18639	0.0251572327044025	0.208773668912448	0.999999999905404	0.999999999995683
GO:0005216	monoatomic ion channel activity	16/2246	448/18639	0.0357142857142857	0.296384047831065	0.999999999962795	0.999999999995683
GO:0005261	monoatomic cation channel activity	8/2246	341/18639	0.0234604105571848	0.194692160452078	0.999999999992382	0.999999999995683
GO:0030371	translation repressor activity	7/2246	329/18639	0.0212765957446809	0.176569219984464	0.999999999995683	0.999999999995683