ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 93/984 175/18639 0.531428571428571 10.0663588850174 8.35288707661437e-72 8.65359101137249e-69 GO:0045296 cadherin binding 58/984 334/18639 0.173652694610778 3.28934204761209 7.48247550907911e-16 3.87592231370298e-13 GO:0019843 rRNA binding 24/984 65/18639 0.369230769230769 6.99399624765478 8.33925645155788e-15 2.87982322793799e-12 GO:0051082 unfolded protein binding 29/984 121/18639 0.239669421487603 4.53983571860512 4.15280286663106e-12 1.07557594245744e-09 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 21/984 68/18639 0.308823529411765 5.84975789096126 2.12353746221476e-11 4.39996962170897e-09 GO:0009055 electron transfer activity 27/984 116/18639 0.232758620689655 4.40893082422204 4.71670518243568e-11 8.1441776150056e-09 GO:0044183 protein folding chaperone 20/984 75/18639 0.266666666666667 5.05121951219512 1.17758835997066e-09 1.74283077275658e-07 GO:0022853 active monoatomic ion transmembrane transporter activity 25/984 118/18639 0.211864406779661 4.01315109549401 2.02260025251253e-09 2.61926732700373e-07 GO:0031720 haptoglobin binding 8/984 10/18639 0.8 15.1536585365854 2.40242259380657e-09 2.76545534131512e-07 GO:0140662 ATP-dependent protein folding chaperone 14/984 40/18639 0.35 6.6297256097561 7.62270439981123e-09 7.89712175820444e-07 GO:0015399 primary active transmembrane transporter activity 29/984 166/18639 0.174698795180723 3.30915736115193 1.16739966624292e-08 1.09947823111606e-06 GO:0055106 ubiquitin-protein transferase regulator activity 13/984 36/18639 0.361111111111111 6.84019308943089 1.69848833287899e-08 1.4663615940522e-06 GO:0004601 peroxidase activity 16/984 57/18639 0.280701754385965 5.31707317073171 2.414757069181e-08 1.92437563359347e-06 GO:0003743 translation initiation factor activity 15/984 51/18639 0.294117647058824 5.57119799139168 3.30010692744281e-08 2.44207912630768e-06 GO:0015078 proton transmembrane transporter activity 30/984 185/18639 0.162162162162162 3.07168754119974 3.82733619227391e-08 2.64341353013051e-06 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 16/984 59/18639 0.271186440677966 5.13683340223233 4.14138227710782e-08 2.68154502442731e-06 GO:0008135 translation factor activity, RNA binding 19/984 83/18639 0.228915662650602 4.33613723185425 4.62809764955601e-08 2.82041715584707e-06 GO:0180051 translation factor activity 19/984 84/18639 0.226190476190476 4.28451655052265 5.68835656149573e-08 3.19353851381024e-06 GO:0016860 intramolecular oxidoreductase activity 15/984 53/18639 0.283018867924528 5.36096410492407 5.85687565274078e-08 3.19353851381024e-06 GO:0005344 oxygen carrier activity 8/984 14/18639 0.571428571428571 10.8240418118467 1.32533413569775e-07 6.86523082291433e-06 GO:0055105 ubiquitin-protein transferase inhibitor activity 8/984 15/18639 0.533333333333333 10.1024390243902 2.70821265539634e-07 1.33605157666219e-05 GO:1990948 ubiquitin ligase inhibitor activity 7/984 11/18639 0.636363636363636 12.0540465631929 3.06351652402983e-07 1.44263778131586e-05 GO:0044389 ubiquitin-like protein ligase binding 40/984 322/18639 0.124223602484472 2.35305256779276 4.43249573668867e-07 1.99655025356933e-05 GO:0031625 ubiquitin protein ligase binding 38/984 302/18639 0.125827814569536 2.38343967048942 6.20853784326654e-07 2.68001883567672e-05 GO:0008137 NADH dehydrogenase (ubiquinone) activity 12/984 41/18639 0.292682926829268 5.54402141582391 8.34393065957873e-07 3.45772486532943e-05 GO:0003954 NADH dehydrogenase activity 12/984 44/18639 0.272727272727273 5.1660199556541 1.92373871584891e-06 7.50324691258043e-05 GO:0048027 mRNA 5'-UTR binding 9/984 24/18639 0.375 7.10327743902439 1.95547940771884e-06 7.50324691258043e-05 GO:0022804 active transmembrane transporter activity 48/984 457/18639 0.105032822757112 1.9895394139937 4.46125942028406e-06 0.00016506659855051 GO:0003697 single-stranded DNA binding 20/984 121/18639 0.165289256198347 3.13092118524491 5.14135793085918e-06 0.000183670579874831 GO:0019825 oxygen binding 10/984 34/18639 0.294117647058824 5.57119799139168 6.5962222730582e-06 0.000227789542496277 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 13/984 58/18639 0.224137931034483 4.24563708999159 7.85621252299726e-06 0.00026254955399436 GO:0016209 antioxidant activity 16/984 86/18639 0.186046511627907 3.5241066364152 9.53596677487433e-06 0.000308726924336556 GO:0004857 enzyme inhibitor activity 43/984 416/18639 0.103365384615385 1.95795467870544 2.05417111131731e-05 0.000644885233734769 GO:0005200 structural constituent of cytoskeleton 18/984 112/18639 0.160714285714286 3.04426175958188 2.23317268898004e-05 0.000680460854642155 GO:0051087 protein-folding chaperone binding 20/984 134/18639 0.149253731343284 2.82717510010921 2.44901239392299e-05 0.000724907668601206 GO:0016853 isomerase activity 24/984 180/18639 0.133333333333333 2.52560975609756 2.73330759766671e-05 0.000786585186439642 GO:0015035 protein-disulfide reductase activity 9/984 34/18639 0.264705882352941 5.01407819225251 4.8649280300718e-05 0.00136217984842011 GO:0043021 ribonucleoprotein complex binding 23/984 177/18639 0.129943502824859 2.46139933856966 5.99555585457117e-05 0.00163457785929888 GO:0004129 cytochrome-c oxidase activity 6/984 15/18639 0.4 7.57682926829268 7.06860289221559e-05 0.00187771092213727 GO:0140517 protein-RNA adaptor activity 7/984 22/18639 0.318181818181818 6.02702328159645 9.47779828798718e-05 0.00245474975658868 GO:0016675 oxidoreductase activity, acting on a heme group of donors 6/984 16/18639 0.375 7.10327743902439 0.000108053900177094 0.00273033757520656 GO:0051540 metal cluster binding 13/984 77/18639 0.168831168831169 3.19801235350016 0.000180639539967397 0.0044557753191958 GO:0015036 disulfide oxidoreductase activity 9/984 40/18639 0.225 4.26196646341463 0.000190654865688494 0.00459345211286697 GO:0016651 oxidoreductase activity, acting on NAD(P)H 14/984 88/18639 0.159090909090909 3.01351164079823 0.000198413008972676 0.00467172448399301 GO:0003756 protein disulfide isomerase activity 6/984 19/18639 0.315789473684211 5.98170731707317 0.000319362750003662 0.00719260454356073 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 6/984 19/18639 0.315789473684211 5.98170731707317 0.000319362750003662 0.00719260454356073 GO:0070182 DNA polymerase binding 6/984 21/18639 0.285714285714286 5.41202090592335 0.000583281341571837 0.0128570099972005 GO:0051536 iron-sulfur cluster binding 12/984 76/18639 0.157894736842105 2.99085365853659 0.000596810713732794 0.0128811645713995 GO:0140104 molecular carrier activity 26/984 249/18639 0.104417670682731 1.97788715838966 0.000726302905767146 0.0153561185790768 GO:0044325 transmembrane transporter binding 17/984 136/18639 0.125 2.36775914634146 0.000826129555416544 0.0171174043882308 GO:0019887 protein kinase regulator activity 26/984 255/18639 0.101960784313725 1.93134863701578 0.00103240939707502 0.0209720810856807 GO:0097027 ubiquitin-protein transferase activator activity 5/984 16/18639 0.3125 5.91939786585366 0.00108768965212194 0.0216701246076601 GO:0030515 snoRNA binding 7/984 32/18639 0.21875 4.14357850609756 0.0011780478577504 0.0230275015213097 GO:0047429 nucleoside triphosphate diphosphatase activity 4/984 10/18639 0.4 7.57682926829268 0.00125462571227165 0.0240702266280265 GO:0031072 heat shock protein binding 16/984 131/18639 0.122137404580153 2.31353565444051 0.0014859736573662 0.0279903401642069 GO:0051015 actin filament binding 22/984 209/18639 0.105263157894737 1.99390243902439 0.00162046845214708 0.0299786663647209 GO:0048029 monosaccharide binding 11/984 74/18639 0.148648648648649 2.81571357943309 0.00165641858572716 0.0301061342949709 GO:0070990 snRNP binding 4/984 11/18639 0.363636363636364 6.8880266075388 0.00188951914602318 0.0330324309068635 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 9/984 54/18639 0.166666666666667 3.15701219512195 0.00191307514904615 0.0330324309068635 GO:0017069 snRNA binding 9/984 54/18639 0.166666666666667 3.15701219512195 0.00191307514904615 0.0330324309068635 GO:0098641 cadherin binding involved in cell-cell adhesion 5/984 18/18639 0.277777777777778 5.26168699186992 0.00195354236895547 0.0331781949875059 GO:0016829 lyase activity 21/984 200/18639 0.105 1.98891768292683 0.00210729283552614 0.0352121835097594 GO:0008301 DNA binding, bending 5/984 19/18639 0.263157894736842 4.98475609756098 0.00253717794715253 0.0413936922563058 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 8/984 46/18639 0.173913043478261 3.29427359490986 0.00255713928996483 0.0413936922563058 GO:0019207 kinase regulator activity 27/984 287/18639 0.0940766550522648 1.78200688365769 0.00269518631153424 0.0426419344594435 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 4/984 12/18639 0.333333333333333 6.3140243902439 0.00271657111421165 0.0426419344594435 GO:0051537 2 iron, 2 sulfur cluster binding 6/984 28/18639 0.214285714285714 4.05901567944251 0.00295173223504263 0.0449705087574141 GO:0097718 disordered domain specific binding 6/984 28/18639 0.214285714285714 4.05901567944251 0.00295173223504263 0.0449705087574141 GO:0005506 iron ion binding 17/984 154/18639 0.11038961038961 2.09100807728856 0.00320497125545183 0.0479161890925257 GO:0000339 RNA cap binding 5/984 20/18639 0.25 4.73551829268293 0.00323758034408958 0.0479161890925257 GO:0019855 calcium channel inhibitor activity 4/984 13/18639 0.307692307692308 5.82833020637899 0.00376129014806014 0.0541207860193098 GO:0043560 insulin receptor substrate binding 4/984 13/18639 0.307692307692308 5.82833020637899 0.00376129014806014 0.0541207860193098 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 9/984 61/18639 0.147540983606557 2.79473210715714 0.0044914701964678 0.0630948581069926 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 7/984 40/18639 0.175 3.31486280487805 0.00452145039984636 0.0630948581069926 GO:0051117 ATPase binding 11/984 84/18639 0.130952380952381 2.48050958188153 0.00456767795176104 0.0630948581069926 GO:0003713 transcription coactivator activity 24/984 256/18639 0.09375 1.7758193597561 0.00470159699366245 0.0640901905978197 GO:0032036 myosin heavy chain binding 4/984 14/18639 0.285714285714286 5.41202090592335 0.00504796714219079 0.0661986577127805 GO:0044548 S100 protein binding 4/984 14/18639 0.285714285714286 5.41202090592335 0.00504796714219079 0.0661986577127805 GO:1990825 sequence-specific mRNA binding 4/984 14/18639 0.285714285714286 5.41202090592335 0.00504796714219079 0.0661986577127805 GO:0061650 ubiquitin-like protein conjugating enzyme activity 7/984 41/18639 0.170731707317073 3.23401249256395 0.00520901207962198 0.0674567064311047 GO:0043022 ribosome binding 13/984 112/18639 0.116071428571429 2.19863349303136 0.00613483813349042 0.0784653371147663 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 4/984 15/18639 0.266666666666667 5.05121951219512 0.00659939029220956 0.0813924802705846 GO:0031386 protein tag activity 4/984 15/18639 0.266666666666667 5.05121951219512 0.00659939029220956 0.0813924802705846 GO:0141047 molecular tag activity 4/984 15/18639 0.266666666666667 5.05121951219512 0.00659939029220956 0.0813924802705846 GO:0003925 G protein activity 8/984 54/18639 0.148148148148148 2.80623306233062 0.00703916645207332 0.085795016992329 GO:0098632 cell-cell adhesion mediator activity 8/984 55/18639 0.145454545454545 2.75521064301552 0.00786587150938911 0.0947563126014781 GO:0020037 heme binding 15/984 142/18639 0.105633802816901 2.00092322226039 0.00810643553336461 0.0965318070409854 GO:0003688 DNA replication origin binding 4/984 16/18639 0.25 4.73551829268293 0.00843662383890544 0.0965988656647775 GO:0008142 oxysterol binding 4/984 16/18639 0.25 4.73551829268293 0.00843662383890544 0.0965988656647775 GO:0017070 U6 snRNA binding 4/984 16/18639 0.25 4.73551829268293 0.00843662383890544 0.0965988656647775 GO:0016835 carbon-oxygen lyase activity 10/984 79/18639 0.126582278481013 2.39773078110528 0.00848503549758181 0.0965988656647775 GO:0019212 phosphatase inhibitor activity 8/984 56/18639 0.142857142857143 2.70601045296167 0.00876338891426571 0.0986833795128182 GO:0004029 aldehyde dehydrogenase (NAD+) activity 4/984 17/18639 0.235294117647059 4.45695839311334 0.0105788424495965 0.114163341435228 GO:0004550 nucleoside diphosphate kinase activity 4/984 17/18639 0.235294117647059 4.45695839311334 0.0105788424495965 0.114163341435228 GO:0051787 misfolded protein binding 4/984 17/18639 0.235294117647059 4.45695839311334 0.0105788424495965 0.114163341435228 GO:1990226 histone methyltransferase binding 4/984 17/18639 0.235294117647059 4.45695839311334 0.0105788424495965 0.114163341435228 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 7/984 48/18639 0.145833333333333 2.76238567073171 0.0124093621913143 0.132537105465996 GO:0004860 protein kinase inhibitor activity 10/984 84/18639 0.119047619047619 2.25500871080139 0.0128589433047184 0.132599324029006 GO:0003746 translation elongation factor activity 4/984 18/18639 0.222222222222222 4.20934959349593 0.0130432139012082 0.132599324029006 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 4/984 18/18639 0.222222222222222 4.20934959349593 0.0130432139012082 0.132599324029006 GO:0015631 tubulin binding 31/984 385/18639 0.0805194805194805 1.52520589166931 0.0131002354227804 0.132599324029006 GO:0001094 TFIID-class transcription factor complex binding 3/984 10/18639 0.3 5.68262195121951 0.0133111290531048 0.132599324029006 GO:0005345 purine nucleobase transmembrane transporter activity 3/984 10/18639 0.3 5.68262195121951 0.0133111290531048 0.132599324029006 GO:0008519 ammonium channel activity 3/984 10/18639 0.3 5.68262195121951 0.0133111290531048 0.132599324029006 GO:0016887 ATP hydrolysis activity 33/984 417/18639 0.079136690647482 1.49901298473416 0.013592032102517 0.134108050078168 GO:0042162 telomeric DNA binding 6/984 38/18639 0.157894736842105 2.99085365853659 0.0138309442600706 0.135177908051256 GO:0046906 tetrapyrrole binding 15/984 152/18639 0.0986842105263158 1.86928353658537 0.0146221270852943 0.141574987480046 GO:0000217 DNA secondary structure binding 6/984 39/18639 0.153846153846154 2.91416510318949 0.0156357302871926 0.149987190532699 GO:0005048 signal sequence binding 7/984 51/18639 0.137254901960784 2.59989239598278 0.0170369828859386 0.158526682203534 GO:0004523 RNA-DNA hybrid ribonuclease activity 3/984 11/18639 0.272727272727273 5.1660199556541 0.0175942327682604 0.158526682203534 GO:0005536 D-glucose binding 3/984 11/18639 0.272727272727273 5.1660199556541 0.0175942327682604 0.158526682203534 GO:0010854 adenylate cyclase regulator activity 3/984 11/18639 0.272727272727273 5.1660199556541 0.0175942327682604 0.158526682203534 GO:0015205 nucleobase transmembrane transporter activity 3/984 11/18639 0.272727272727273 5.1660199556541 0.0175942327682604 0.158526682203534 GO:0050786 RAGE receptor binding 3/984 11/18639 0.272727272727273 5.1660199556541 0.0175942327682604 0.158526682203534 GO:0050997 quaternary ammonium group binding 6/984 40/18639 0.15 2.84131097560976 0.0175970737967243 0.158526682203534 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 13/984 128/18639 0.1015625 1.92380430640244 0.017771825388036 0.158720785362115 GO:0098631 cell adhesion mediator activity 9/984 76/18639 0.118421052631579 2.24314024390244 0.0183539121032051 0.162518401187355 GO:0000287 magnesium ion binding 20/984 230/18639 0.0869565217391304 1.64713679745493 0.0198545305290369 0.174316047695612 GO:0019210 kinase inhibitor activity 10/984 90/18639 0.111111111111111 2.10467479674797 0.0201238838647325 0.175196165410612 GO:0019208 phosphatase regulator activity 12/984 117/18639 0.102564102564103 1.94277673545966 0.0207238412491705 0.178110017334078 GO:0008017 microtubule binding 23/984 276/18639 0.0833333333333333 1.57850609756098 0.0208024248044628 0.178110017334078 GO:0051879 Hsp90 protein binding 6/984 42/18639 0.142857142857143 2.70601045296167 0.0220121767343154 0.186923074563531 GO:0010853 cyclase activator activity 3/984 12/18639 0.25 4.73551829268293 0.02255345331961 0.188430464831581 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/984 12/18639 0.25 4.73551829268293 0.02255345331961 0.188430464831581 GO:0008200 ion channel inhibitor activity 6/984 43/18639 0.13953488372093 2.6430799773114 0.0244764763757534 0.202861036202245 GO:0000049 tRNA binding 9/984 80/18639 0.1125 2.13098323170732 0.0248346428014861 0.203620026251333 GO:0031369 translation initiation factor binding 5/984 32/18639 0.15625 2.95969893292683 0.0249611422142078 0.203620026251333 GO:0070034 telomerase RNA binding 4/984 22/18639 0.181818181818182 3.4440133037694 0.0263920714099782 0.213610827974511 GO:0016248 channel inhibitor activity 6/984 44/18639 0.136363636363636 2.58300997782705 0.0271183706945129 0.217150792836489 GO:0030170 pyridoxal phosphate binding 7/984 56/18639 0.125 2.36775914634146 0.0272486516107564 0.217150792836489 GO:0019842 vitamin binding 14/984 150/18639 0.0933333333333333 1.76792682926829 0.0275262120449657 0.217688211286905 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 3/984 13/18639 0.230769230769231 4.37124765478424 0.028191102271075 0.217955089200252 GO:0005542 folic acid binding 3/984 13/18639 0.230769230769231 4.37124765478424 0.028191102271075 0.217955089200252 GO:0045159 myosin II binding 3/984 13/18639 0.230769230769231 4.37124765478424 0.028191102271075 0.217955089200252 GO:0003779 actin binding 33/984 443/18639 0.0744920993227991 1.41103479601387 0.0295766405178836 0.226248138110043 GO:0070279 vitamin B6 binding 7/984 57/18639 0.12280701754386 2.32621951219512 0.0297005277827855 0.226248138110043 GO:0141110 transporter inhibitor activity 6/984 45/18639 0.133333333333333 2.52560975609756 0.0299422054686772 0.226424269091603 GO:0004602 glutathione peroxidase activity 4/984 23/18639 0.173913043478261 3.29427359490986 0.0306510555026498 0.230105025367718 GO:0045309 protein phosphorylated amino acid binding 7/984 59/18639 0.11864406779661 2.24736461347664 0.0350403347019684 0.258100191335557 GO:0001091 RNA polymerase II general transcription initiation factor binding 4/984 24/18639 0.166666666666667 3.15701219512195 0.0352910512040415 0.258100191335557 GO:0005540 hyaluronic acid binding 4/984 24/18639 0.166666666666667 3.15701219512195 0.0352910512040415 0.258100191335557 GO:0061631 ubiquitin conjugating enzyme activity 5/984 35/18639 0.142857142857143 2.70601045296167 0.0353766671521709 0.258100191335557 GO:0003684 damaged DNA binding 8/984 74/18639 0.108108108108108 2.04779169413316 0.0408503872274267 0.295951057116182 GO:0033130 acetylcholine receptor binding 3/984 15/18639 0.2 3.78841463414634 0.0414787354233655 0.298416457629213 GO:0003725 double-stranded RNA binding 8/984 75/18639 0.106666666666667 2.02048780487805 0.0437045054258435 0.312261156008096 GO:0005159 insulin-like growth factor receptor binding 3/984 16/18639 0.1875 3.5516387195122 0.0491038380967024 0.348435453891669 GO:0004364 glutathione transferase activity 4/984 27/18639 0.148148148148148 2.80623306233062 0.0515145976688837 0.358182034798413 GO:0008320 protein transmembrane transporter activity 4/984 27/18639 0.148148148148148 2.80623306233062 0.0515145976688837 0.358182034798413 GO:0023026 MHC class II protein complex binding 4/984 27/18639 0.148148148148148 2.80623306233062 0.0515145976688837 0.358182034798413 GO:0016776 phosphotransferase activity, phosphate group as acceptor 5/984 39/18639 0.128205128205128 2.42847091932458 0.0528992535530653 0.365357511206504 GO:0019888 protein phosphatase regulator activity 10/984 107/18639 0.0934579439252336 1.77028721221792 0.0562034680110064 0.385607899731144 GO:0046625 sphingolipid binding 4/984 28/18639 0.142857142857143 2.70601045296167 0.0576871787194135 0.393183665482319 GO:0004864 protein phosphatase inhibitor activity 6/984 53/18639 0.113207547169811 2.14438564196963 0.0594675433112093 0.400054382275408 GO:0005246 calcium channel regulator activity 6/984 53/18639 0.113207547169811 2.14438564196963 0.0594675433112093 0.400054382275408 GO:0140297 DNA-binding transcription factor binding 34/984 488/18639 0.069672131147541 1.31973460615754 0.060598390497121 0.405031822935596 GO:0001530 lipopolysaccharide binding 5/984 41/18639 0.121951219512195 2.31000892325996 0.0632509888355229 0.418546841707183 GO:0051287 NAD binding 6/984 54/18639 0.111111111111111 2.10467479674797 0.0640553389485127 0.418546841707183 GO:0003785 actin monomer binding 4/984 29/18639 0.137931034482759 2.61269974768713 0.0642364361307356 0.418546841707183 GO:0106222 lncRNA binding 4/984 29/18639 0.137931034482759 2.61269974768713 0.0642364361307356 0.418546841707183 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 3/984 18/18639 0.166666666666667 3.15701219512195 0.0662223903879142 0.42089813768024 GO:0031690 adrenergic receptor binding 3/984 18/18639 0.166666666666667 3.15701219512195 0.0662223903879142 0.42089813768024 GO:0070628 proteasome binding 3/984 18/18639 0.166666666666667 3.15701219512195 0.0662223903879142 0.42089813768024 GO:1990381 ubiquitin-specific protease binding 3/984 18/18639 0.166666666666667 3.15701219512195 0.0662223903879142 0.42089813768024 GO:0030246 carbohydrate binding 21/984 280/18639 0.075 1.42065548780488 0.0672452362526572 0.424413441236731 GO:0008307 structural constituent of muscle 5/984 42/18639 0.119047619047619 2.25500871080139 0.068823801281632 0.424413441236731 GO:0031492 nucleosomal DNA binding 5/984 42/18639 0.119047619047619 2.25500871080139 0.068823801281632 0.424413441236731 GO:0035198 miRNA binding 5/984 42/18639 0.119047619047619 2.25500871080139 0.068823801281632 0.424413441236731 GO:0042056 chemoattractant activity 5/984 42/18639 0.119047619047619 2.25500871080139 0.068823801281632 0.424413441236731 GO:0031210 phosphatidylcholine binding 4/984 30/18639 0.133333333333333 2.52560975609756 0.0711566999192006 0.436203201871549 GO:0030506 ankyrin binding 3/984 19/18639 0.157894736842105 2.99085365853659 0.0756681841814688 0.455768830302335 GO:0046624 sphingolipid transporter activity 3/984 19/18639 0.157894736842105 2.99085365853659 0.0756681841814688 0.455768830302335 GO:0097001 ceramide binding 3/984 19/18639 0.157894736842105 2.99085365853659 0.0756681841814688 0.455768830302335 GO:0019205 nucleobase-containing compound kinase activity 5/984 44/18639 0.113636363636364 2.15250831485588 0.0807539249596657 0.483589978371178 GO:0010851 cyclase regulator activity 3/984 20/18639 0.15 2.84131097560976 0.0856690459296388 0.50101030588699 GO:0042288 MHC class I protein binding 3/984 20/18639 0.15 2.84131097560976 0.0856690459296388 0.50101030588699 GO:0043024 ribosomal small subunit binding 3/984 20/18639 0.15 2.84131097560976 0.0856690459296388 0.50101030588699 GO:0022884 macromolecule transmembrane transporter activity 4/984 32/18639 0.125 2.36775914634146 0.0860809212817415 0.50101030588699 GO:0140142 nucleocytoplasmic carrier activity 4/984 32/18639 0.125 2.36775914634146 0.0860809212817415 0.50101030588699 GO:0043539 protein serine/threonine kinase activator activity 7/984 73/18639 0.0958904109589041 1.8163631807551 0.0899542240097969 0.507605714688302 GO:0061134 peptidase regulator activity 17/984 226/18639 0.0752212389380531 1.4248462119577 0.0904428008957953 0.507605714688302 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/984 10/18639 0.2 3.78841463414634 0.0945636128714694 0.507605714688302 GO:0005337 nucleoside transmembrane transporter activity 2/984 10/18639 0.2 3.78841463414634 0.0945636128714694 0.507605714688302 GO:0005522 profilin binding 2/984 10/18639 0.2 3.78841463414634 0.0945636128714694 0.507605714688302 GO:0005528 FK506 binding 2/984 10/18639 0.2 3.78841463414634 0.0945636128714694 0.507605714688302 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/984 10/18639 0.2 3.78841463414634 0.0945636128714694 0.507605714688302 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/984 10/18639 0.2 3.78841463414634 0.0945636128714694 0.507605714688302 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 2/984 10/18639 0.2 3.78841463414634 0.0945636128714694 0.507605714688302 GO:0030957 Tat protein binding 2/984 10/18639 0.2 3.78841463414634 0.0945636128714694 0.507605714688302 GO:0031996 thioesterase binding 2/984 10/18639 0.2 3.78841463414634 0.0945636128714694 0.507605714688302 GO:0035374 chondroitin sulfate binding 2/984 10/18639 0.2 3.78841463414634 0.0945636128714694 0.507605714688302 GO:0050815 phosphoserine residue binding 2/984 10/18639 0.2 3.78841463414634 0.0945636128714694 0.507605714688302 GO:0098505 G-rich strand telomeric DNA binding 2/984 10/18639 0.2 3.78841463414634 0.0945636128714694 0.507605714688302 GO:1990757 ubiquitin ligase activator activity 2/984 10/18639 0.2 3.78841463414634 0.0945636128714694 0.507605714688302 GO:0031491 nucleosome binding 7/984 74/18639 0.0945945945945946 1.79181773236651 0.0950844756139251 0.507770704824879 GO:0015174 basic amino acid transmembrane transporter activity 3/984 21/18639 0.142857142857143 2.70601045296167 0.0961956405978223 0.508462671731346 GO:0072542 protein phosphatase activator activity 3/984 21/18639 0.142857142857143 2.70601045296167 0.0961956405978223 0.508462671731346 GO:0016836 hydro-lyase activity 6/984 61/18639 0.0983606557377049 1.86315473810476 0.101778478972526 0.530377330259026 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 4/984 34/18639 0.117647058823529 2.22847919655667 0.102389445995951 0.530377330259026 GO:0051427 hormone receptor binding 4/984 34/18639 0.117647058823529 2.22847919655667 0.102389445995951 0.530377330259026 GO:0090482 vitamin transmembrane transporter activity 4/984 34/18639 0.117647058823529 2.22847919655667 0.102389445995951 0.530377330259026 GO:0061135 endopeptidase regulator activity 14/984 184/18639 0.0760869565217391 1.44124469777306 0.108538950960033 0.550960862025954 GO:0003774 cytoskeletal motor activity 12/984 153/18639 0.0784313725490196 1.48565279770445 0.110767289961845 0.550960862025954 GO:0008199 ferric iron binding 2/984 11/18639 0.181818181818182 3.4440133037694 0.111667919561071 0.550960862025954 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/984 11/18639 0.181818181818182 3.4440133037694 0.111667919561071 0.550960862025954 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 2/984 11/18639 0.181818181818182 3.4440133037694 0.111667919561071 0.550960862025954 GO:0032794 GTPase activating protein binding 2/984 11/18639 0.181818181818182 3.4440133037694 0.111667919561071 0.550960862025954 GO:0034511 U3 snoRNA binding 2/984 11/18639 0.181818181818182 3.4440133037694 0.111667919561071 0.550960862025954 GO:0050998 nitric-oxide synthase binding 2/984 11/18639 0.181818181818182 3.4440133037694 0.111667919561071 0.550960862025954 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/984 11/18639 0.181818181818182 3.4440133037694 0.111667919561071 0.550960862025954 GO:0030414 peptidase inhibitor activity 13/984 169/18639 0.0769230769230769 1.45708255159475 0.111681255816072 0.550960862025954 GO:0060590 ATPase regulator activity 5/984 49/18639 0.102040816326531 1.93286460925834 0.114989528270036 0.564593134065202 GO:0030295 protein kinase activator activity 11/984 139/18639 0.079136690647482 1.49901298473416 0.117539307635047 0.565069794720812 GO:0051219 phosphoprotein binding 8/984 93/18639 0.0860215053763441 1.6294256490952 0.117821280175745 0.565069794720812 GO:0017134 fibroblast growth factor binding 3/984 23/18639 0.130434782608696 2.4707051961824 0.118702186977786 0.565069794720812 GO:0043274 phospholipase binding 3/984 23/18639 0.130434782608696 2.4707051961824 0.118702186977786 0.565069794720812 GO:0099186 structural constituent of postsynapse 3/984 23/18639 0.130434782608696 2.4707051961824 0.118702186977786 0.565069794720812 GO:0004869 cysteine-type endopeptidase inhibitor activity 4/984 36/18639 0.111111111111111 2.10467479674797 0.119995516253454 0.565069794720812 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 4/984 36/18639 0.111111111111111 2.10467479674797 0.119995516253454 0.565069794720812 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 4/984 36/18639 0.111111111111111 2.10467479674797 0.119995516253454 0.565069794720812 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 4/984 36/18639 0.111111111111111 2.10467479674797 0.119995516253454 0.565069794720812 GO:0046982 protein heterodimerization activity 25/984 369/18639 0.0677506775067751 1.28333829069998 0.120961676015357 0.567042064940767 GO:0023023 MHC protein complex binding 4/984 37/18639 0.108108108108108 2.04779169413316 0.129254377168105 0.572310600124883 GO:0000340 RNA 7-methylguanosine cap binding 2/984 12/18639 0.166666666666667 3.15701219512195 0.129490812809364 0.572310600124883 GO:0005049 nuclear export signal receptor activity 2/984 12/18639 0.166666666666667 3.15701219512195 0.129490812809364 0.572310600124883 GO:0005527 macrolide binding 2/984 12/18639 0.166666666666667 3.15701219512195 0.129490812809364 0.572310600124883 GO:0015132 prostaglandin transmembrane transporter activity 2/984 12/18639 0.166666666666667 3.15701219512195 0.129490812809364 0.572310600124883 GO:0015368 calcium:monoatomic cation antiporter activity 2/984 12/18639 0.166666666666667 3.15701219512195 0.129490812809364 0.572310600124883 GO:0016840 carbon-nitrogen lyase activity 2/984 12/18639 0.166666666666667 3.15701219512195 0.129490812809364 0.572310600124883 GO:0017166 vinculin binding 2/984 12/18639 0.166666666666667 3.15701219512195 0.129490812809364 0.572310600124883 GO:0043047 single-stranded telomeric DNA binding 2/984 12/18639 0.166666666666667 3.15701219512195 0.129490812809364 0.572310600124883 GO:0097371 MDM2/MDM4 family protein binding 2/984 12/18639 0.166666666666667 3.15701219512195 0.129490812809364 0.572310600124883 GO:1990459 transferrin receptor binding 2/984 12/18639 0.166666666666667 3.15701219512195 0.129490812809364 0.572310600124883 GO:0015295 solute:proton symporter activity 3/984 24/18639 0.125 2.36775914634146 0.130618063516892 0.572310600124883 GO:0042625 ATPase-coupled ion transmembrane transporter activity 3/984 24/18639 0.125 2.36775914634146 0.130618063516892 0.572310600124883 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 3/984 24/18639 0.125 2.36775914634146 0.130618063516892 0.572310600124883 GO:0046961 proton-transporting ATPase activity, rotational mechanism 3/984 24/18639 0.125 2.36775914634146 0.130618063516892 0.572310600124883 GO:0042826 histone deacetylase binding 10/984 127/18639 0.078740157480315 1.49150182446706 0.134312016812832 0.572310600124883 GO:0033192 calmodulin-dependent protein phosphatase activity 7/984 81/18639 0.0864197530864197 1.63696928635953 0.135343723002506 0.572310600124883 GO:0140791 histone H2AXS140 phosphatase activity 7/984 81/18639 0.0864197530864197 1.63696928635953 0.135343723002506 0.572310600124883 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 7/984 81/18639 0.0864197530864197 1.63696928635953 0.135343723002506 0.572310600124883 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 7/984 81/18639 0.0864197530864197 1.63696928635953 0.135343723002506 0.572310600124883 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 7/984 81/18639 0.0864197530864197 1.63696928635953 0.135343723002506 0.572310600124883 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 7/984 81/18639 0.0864197530864197 1.63696928635953 0.135343723002506 0.572310600124883 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 7/984 81/18639 0.0864197530864197 1.63696928635953 0.135343723002506 0.572310600124883 GO:1990439 MAP kinase serine/threonine phosphatase activity 7/984 81/18639 0.0864197530864197 1.63696928635953 0.135343723002506 0.572310600124883 GO:0043531 ADP binding 4/984 38/18639 0.105263157894737 1.99390243902439 0.138799376979013 0.583903431903908 GO:0031490 chromatin DNA binding 10/984 128/18639 0.078125 1.47984946646341 0.139260569607884 0.583903431903908 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 7/984 82/18639 0.0853658536585366 1.61700624628198 0.141689803332148 0.583903431903908 GO:0033549 MAP kinase phosphatase activity 7/984 82/18639 0.0853658536585366 1.61700624628198 0.141689803332148 0.583903431903908 GO:0019211 phosphatase activator activity 3/984 25/18639 0.12 2.2730487804878 0.142932154317015 0.583903431903908 GO:0042974 nuclear retinoic acid receptor binding 3/984 25/18639 0.12 2.2730487804878 0.142932154317015 0.583903431903908 GO:0004866 endopeptidase inhibitor activity 12/984 161/18639 0.0745341614906832 1.41183154067566 0.144521983851798 0.583903431903908 GO:0042626 ATPase-coupled transmembrane transporter activity 8/984 98/18639 0.0816326530612245 1.54629168740667 0.145982857517747 0.583903431903908 GO:0005172 vascular endothelial growth factor receptor binding 2/984 13/18639 0.153846153846154 2.91416510318949 0.147908941998143 0.583903431903908 GO:0008035 high-density lipoprotein particle binding 2/984 13/18639 0.153846153846154 2.91416510318949 0.147908941998143 0.583903431903908 GO:0008253 5'-nucleotidase activity 2/984 13/18639 0.153846153846154 2.91416510318949 0.147908941998143 0.583903431903908 GO:0030955 potassium ion binding 2/984 13/18639 0.153846153846154 2.91416510318949 0.147908941998143 0.583903431903908 GO:0031432 titin binding 2/984 13/18639 0.153846153846154 2.91416510318949 0.147908941998143 0.583903431903908 GO:0061459 L-arginine transmembrane transporter activity 2/984 13/18639 0.153846153846154 2.91416510318949 0.147908941998143 0.583903431903908 GO:0071714 icosanoid transmembrane transporter activity 2/984 13/18639 0.153846153846154 2.91416510318949 0.147908941998143 0.583903431903908 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/984 13/18639 0.153846153846154 2.91416510318949 0.147908941998143 0.583903431903908 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 7/984 83/18639 0.0843373493975904 1.59752424331472 0.148176400502175 0.583903431903908 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 4/984 39/18639 0.102564102564103 1.94277673545966 0.148616533941978 0.583903431903908 GO:0030145 manganese ion binding 6/984 68/18639 0.0882352941176471 1.6713593974175 0.14879392473227 0.583903431903908 GO:0001221 transcription coregulator binding 9/984 115/18639 0.0782608695652174 1.48242311770944 0.153947304801845 0.601543434421211 GO:0017018 myosin phosphatase activity 7/984 84/18639 0.0833333333333333 1.57850609756098 0.154800305541541 0.601543434421211 GO:0008198 ferrous iron binding 3/984 26/18639 0.115384615384615 2.18562382739212 0.155611622031742 0.601543434421211 GO:0050681 nuclear androgen receptor binding 3/984 26/18639 0.115384615384615 2.18562382739212 0.155611622031742 0.601543434421211 GO:0061791 GTPase motor activity 4/984 40/18639 0.1 1.89420731707317 0.1586914352589 0.60732368683818 GO:1990606 membrane scission GTPase motor activity 4/984 40/18639 0.1 1.89420731707317 0.1586914352589 0.60732368683818 GO:0019209 kinase activator activity 11/984 148/18639 0.0743243243243243 1.40785678971655 0.159509855221453 0.60732368683818 GO:0033218 amide binding 17/984 247/18639 0.0688259109311741 1.30370544090056 0.16003799855871 0.60732368683818 GO:0042393 histone binding 17/984 247/18639 0.0688259109311741 1.30370544090056 0.16003799855871 0.60732368683818 GO:0008028 monocarboxylic acid transmembrane transporter activity 6/984 70/18639 0.0857142857142857 1.623606271777 0.163761643563996 0.610082428319298 GO:0097110 scaffold protein binding 6/984 70/18639 0.0857142857142857 1.623606271777 0.163761643563996 0.610082428319298 GO:0008559 ABC-type xenobiotic transporter activity 2/984 14/18639 0.142857142857143 2.70601045296167 0.166809954598312 0.610082428319298 GO:0016530 metallochaperone activity 2/984 14/18639 0.142857142857143 2.70601045296167 0.166809954598312 0.610082428319298 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2/984 14/18639 0.142857142857143 2.70601045296167 0.166809954598312 0.610082428319298 GO:0070742 C2H2 zinc finger domain binding 2/984 14/18639 0.142857142857143 2.70601045296167 0.166809954598312 0.610082428319298 GO:0071933 Arp2/3 complex binding 2/984 14/18639 0.142857142857143 2.70601045296167 0.166809954598312 0.610082428319298 GO:0098847 sequence-specific single stranded DNA binding 2/984 14/18639 0.142857142857143 2.70601045296167 0.166809954598312 0.610082428319298 GO:1901474 azole transmembrane transporter activity 2/984 14/18639 0.142857142857143 2.70601045296167 0.166809954598312 0.610082428319298 GO:0001671 ATPase activator activity 3/984 27/18639 0.111111111111111 2.10467479674797 0.168623750077099 0.610082428319298 GO:0008266 poly(U) RNA binding 3/984 27/18639 0.111111111111111 2.10467479674797 0.168623750077099 0.610082428319298 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/984 27/18639 0.111111111111111 2.10467479674797 0.168623750077099 0.610082428319298 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 4/984 41/18639 0.0975609756097561 1.84800713860797 0.169009321358724 0.610082428319298 GO:0140318 protein transporter activity 4/984 41/18639 0.0975609756097561 1.84800713860797 0.169009321358724 0.610082428319298 GO:0170055 lipid transmembrane transporter activity 5/984 56/18639 0.0892857142857143 1.69125653310105 0.172398898855066 0.620157150048084 GO:0004722 protein serine/threonine phosphatase activity 8/984 103/18639 0.0776699029126214 1.4712289841345 0.177111410104557 0.634904570478621 GO:0016859 cis-trans isomerase activity 4/984 42/18639 0.0952380952380952 1.80400696864111 0.179555165577366 0.639241070577838 GO:0019894 kinesin binding 4/984 42/18639 0.0952380952380952 1.80400696864111 0.179555165577366 0.639241070577838 GO:0008514 organic anion transmembrane transporter activity 18/984 269/18639 0.0669144981412639 1.26749931997461 0.180193259381242 0.639315810681394 GO:0015291 secondary active transmembrane transporter activity 19/984 287/18639 0.0662020905923345 1.25400484405541 0.184052598728765 0.64694960109978 GO:0003712 transcription coregulator activity 31/984 495/18639 0.0626262626262626 1.18627124907613 0.184995076338661 0.64694960109978 GO:0000774 adenyl-nucleotide exchange factor activity 2/984 15/18639 0.133333333333333 2.52560975609756 0.186091680625226 0.64694960109978 GO:0004559 alpha-mannosidase activity 2/984 15/18639 0.133333333333333 2.52560975609756 0.186091680625226 0.64694960109978 GO:0008252 nucleotidase activity 2/984 15/18639 0.133333333333333 2.52560975609756 0.186091680625226 0.64694960109978 GO:0016846 carbon-sulfur lyase activity 2/984 15/18639 0.133333333333333 2.52560975609756 0.186091680625226 0.64694960109978 GO:0016922 nuclear receptor binding 10/984 137/18639 0.072992700729927 1.3826330781556 0.187870827529436 0.649283906336204 GO:0003727 single-stranded RNA binding 7/984 89/18639 0.0786516853932584 1.48982597972047 0.189855526008846 0.649283906336204 GO:0004712 protein serine/threonine/tyrosine kinase activity 4/984 43/18639 0.0930232558139535 1.7620533182076 0.190313749163624 0.649283906336204 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 4/984 43/18639 0.0930232558139535 1.7620533182076 0.190313749163624 0.649283906336204 GO:0048156 tau protein binding 4/984 43/18639 0.0930232558139535 1.7620533182076 0.190313749163624 0.649283906336204 GO:0061980 regulatory RNA binding 5/984 58/18639 0.0862068965517241 1.63293734230446 0.190523462863133 0.649283906336204 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 3/984 29/18639 0.103448275862069 1.95952481076535 0.195516873544939 0.659789840366635 GO:0043236 laminin binding 3/984 29/18639 0.103448275862069 1.95952481076535 0.195516873544939 0.659789840366635 GO:0097472 cyclin-dependent protein kinase activity 3/984 29/18639 0.103448275862069 1.95952481076535 0.195516873544939 0.659789840366635 GO:0036002 pre-mRNA binding 5/984 59/18639 0.0847457627118644 1.6052604381976 0.199830093912234 0.672155770432062 GO:0072341 modified amino acid binding 7/984 91/18639 0.0769230769230769 1.45708255159475 0.204708708550076 0.68198339231631 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/984 16/18639 0.125 2.36775914634146 0.205661372415015 0.68198339231631 GO:0015923 mannosidase activity 2/984 16/18639 0.125 2.36775914634146 0.205661372415015 0.68198339231631 GO:0070411 I-SMAD binding 2/984 16/18639 0.125 2.36775914634146 0.205661372415015 0.68198339231631 GO:0001098 basal transcription machinery binding 5/984 60/18639 0.0833333333333333 1.57850609756098 0.209287530816647 0.68198339231631 GO:0001099 basal RNA polymerase II transcription machinery binding 5/984 60/18639 0.0833333333333333 1.57850609756098 0.209287530816647 0.68198339231631 GO:0008187 poly-pyrimidine tract binding 3/984 30/18639 0.1 1.89420731707317 0.209334670614466 0.68198339231631 GO:0016769 transferase activity, transferring nitrogenous groups 3/984 30/18639 0.1 1.89420731707317 0.209334670614466 0.68198339231631 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/984 30/18639 0.1 1.89420731707317 0.209334670614466 0.68198339231631 GO:0098918 structural constituent of synapse 3/984 30/18639 0.1 1.89420731707317 0.209334670614466 0.68198339231631 GO:0017022 myosin binding 6/984 76/18639 0.0789473684210526 1.49542682926829 0.212150872126346 0.687669980999832 GO:0051539 4 iron, 4 sulfur cluster binding 4/984 45/18639 0.0888888888888889 1.68373983739837 0.212407716138944 0.687669980999832 GO:0047499 calcium-independent phospholipase A2 activity 3/984 31/18639 0.0967741935483871 1.8331038552321 0.223358997941198 0.709880413448748 GO:0004659 prenyltransferase activity 2/984 17/18639 0.117647058823529 2.22847919655667 0.225434996162778 0.709880413448748 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/984 17/18639 0.117647058823529 2.22847919655667 0.225434996162778 0.709880413448748 GO:0016018 cyclosporin A binding 2/984 17/18639 0.117647058823529 2.22847919655667 0.225434996162778 0.709880413448748 GO:0030548 acetylcholine receptor regulator activity 2/984 17/18639 0.117647058823529 2.22847919655667 0.225434996162778 0.709880413448748 GO:0032977 membrane insertase activity 2/984 17/18639 0.117647058823529 2.22847919655667 0.225434996162778 0.709880413448748 GO:0046965 nuclear retinoid X receptor binding 2/984 17/18639 0.117647058823529 2.22847919655667 0.225434996162778 0.709880413448748 GO:0070402 NADPH binding 2/984 17/18639 0.117647058823529 2.22847919655667 0.225434996162778 0.709880413448748 GO:0070492 oligosaccharide binding 2/984 17/18639 0.117647058823529 2.22847919655667 0.225434996162778 0.709880413448748 GO:0019903 protein phosphatase binding 10/984 144/18639 0.0694444444444444 1.31542174796748 0.230222242027564 0.72275831133502 GO:0005178 integrin binding 11/984 161/18639 0.0683229813664596 1.29417891228602 0.23126542570325 0.72383982183857 GO:0001784 phosphotyrosine residue binding 4/984 47/18639 0.0851063829787234 1.61209133367929 0.235168185297062 0.728767839451782 GO:0005504 fatty acid binding 4/984 47/18639 0.0851063829787234 1.61209133367929 0.235168185297062 0.728767839451782 GO:0043495 protein-membrane adaptor activity 4/984 47/18639 0.0851063829787234 1.61209133367929 0.235168185297062 0.728767839451782 GO:0004867 serine-type endopeptidase inhibitor activity 7/984 95/18639 0.0736842105263158 1.39573170731707 0.235653693259022 0.728767839451782 GO:0042910 xenobiotic transmembrane transporter activity 3/984 32/18639 0.09375 1.7758193597561 0.23756017828528 0.730303693482343 GO:0047498 calcium-dependent phospholipase A2 activity 3/984 32/18639 0.09375 1.7758193597561 0.23756017828528 0.730303693482343 GO:1901682 sulfur compound transmembrane transporter activity 5/984 63/18639 0.0793650793650794 1.50333914053426 0.23847208131725 0.730369794461158 GO:0140097 catalytic activity, acting on DNA 21/984 336/18639 0.0625 1.18387957317073 0.242234085494945 0.730369794461158 GO:0015293 symporter activity 10/984 146/18639 0.0684931506849315 1.29740227196793 0.242946647956099 0.730369794461158 GO:0016407 acetyltransferase activity 7/984 96/18639 0.0729166666666667 1.38119283536585 0.243621663627111 0.730369794461158 GO:0000400 four-way junction DNA binding 2/984 18/18639 0.111111111111111 2.10467479674797 0.245336571884636 0.730369794461158 GO:0000900 mRNA regulatory element binding translation repressor activity 2/984 18/18639 0.111111111111111 2.10467479674797 0.245336571884636 0.730369794461158 GO:0008308 voltage-gated monoatomic anion channel activity 2/984 18/18639 0.111111111111111 2.10467479674797 0.245336571884636 0.730369794461158 GO:0008525 phosphatidylcholine transporter activity 2/984 18/18639 0.111111111111111 2.10467479674797 0.245336571884636 0.730369794461158 GO:0034185 apolipoprotein binding 2/984 18/18639 0.111111111111111 2.10467479674797 0.245336571884636 0.730369794461158 GO:0099602 neurotransmitter receptor regulator activity 2/984 18/18639 0.111111111111111 2.10467479674797 0.245336571884636 0.730369794461158 GO:1901611 phosphatidylglycerol binding 2/984 18/18639 0.111111111111111 2.10467479674797 0.245336571884636 0.730369794461158 GO:0048306 calcium-dependent protein binding 6/984 80/18639 0.075 1.42065548780488 0.246843532475249 0.732750428780395 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 9/984 130/18639 0.0692307692307692 1.31137429643527 0.248672515982044 0.73607064730685 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3/984 33/18639 0.0909090909090909 1.7220066518847 0.251909473625444 0.741415382602158 GO:0071889 14-3-3 protein binding 3/984 33/18639 0.0909090909090909 1.7220066518847 0.251909473625444 0.741415382602158 GO:0001618 virus receptor activity 6/984 81/18639 0.0740740740740741 1.40311653116531 0.255763517233068 0.745861630412138 GO:0015101 organic cation transmembrane transporter activity 6/984 81/18639 0.0740740740740741 1.40311653116531 0.255763517233068 0.745861630412138 GO:0017124 SH3 domain binding 8/984 115/18639 0.0695652173913043 1.31770943796394 0.261848778768358 0.745861630412138 GO:0005179 hormone activity 9/984 132/18639 0.0681818181818182 1.29150498891353 0.262604239128955 0.745861630412138 GO:0140272 exogenous protein binding 6/984 82/18639 0.0731707317073171 1.38600535395598 0.264769336751562 0.745861630412138 GO:0008381 mechanosensitive monoatomic ion channel activity 2/984 19/18639 0.105263157894737 1.99390243902439 0.265297558673244 0.745861630412138 GO:0015245 fatty acid transmembrane transporter activity 2/984 19/18639 0.105263157894737 1.99390243902439 0.265297558673244 0.745861630412138 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/984 19/18639 0.105263157894737 1.99390243902439 0.265297558673244 0.745861630412138 GO:0022840 leak channel activity 2/984 19/18639 0.105263157894737 1.99390243902439 0.265297558673244 0.745861630412138 GO:0022842 narrow pore channel activity 2/984 19/18639 0.105263157894737 1.99390243902439 0.265297558673244 0.745861630412138 GO:0031420 alkali metal ion binding 2/984 19/18639 0.105263157894737 1.99390243902439 0.265297558673244 0.745861630412138 GO:0034987 immunoglobulin receptor binding 2/984 19/18639 0.105263157894737 1.99390243902439 0.265297558673244 0.745861630412138 GO:0043395 heparan sulfate proteoglycan binding 2/984 19/18639 0.105263157894737 1.99390243902439 0.265297558673244 0.745861630412138 GO:0050145 nucleoside monophosphate kinase activity 2/984 19/18639 0.105263157894737 1.99390243902439 0.265297558673244 0.745861630412138 GO:0070003 threonine-type peptidase activity 2/984 19/18639 0.105263157894737 1.99390243902439 0.265297558673244 0.745861630412138 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 3/984 34/18639 0.0882352941176471 1.6713593974175 0.266379153718621 0.745861630412138 GO:0016831 carboxy-lyase activity 3/984 34/18639 0.0882352941176471 1.6713593974175 0.266379153718621 0.745861630412138 GO:0030332 cyclin binding 3/984 34/18639 0.0882352941176471 1.6713593974175 0.266379153718621 0.745861630412138 GO:0005525 GTP binding 23/984 378/18639 0.0608465608465608 1.15256000774293 0.269981062810163 0.753909382941587 GO:0016247 channel regulator activity 11/984 168/18639 0.0654761904761905 1.24025479094077 0.274316309270046 0.763956173128409 GO:0043130 ubiquitin binding 7/984 100/18639 0.07 1.32594512195122 0.276279887342161 0.767361831867235 GO:0004623 phospholipase A2 activity 3/984 35/18639 0.0857142857142857 1.623606271777 0.280942550363865 0.771607071735335 GO:0005154 epidermal growth factor receptor binding 3/984 35/18639 0.0857142857142857 1.623606271777 0.280942550363865 0.771607071735335 GO:0016229 steroid dehydrogenase activity 3/984 35/18639 0.0857142857142857 1.623606271777 0.280942550363865 0.771607071735335 GO:0016830 carbon-carbon lyase activity 4/984 51/18639 0.0784313725490196 1.48565279770445 0.282202795002699 0.771607071735335 GO:0004527 exonuclease activity 6/984 84/18639 0.0714285714285714 1.35300522648084 0.283012515620813 0.771607071735335 GO:0005326 neurotransmitter transmembrane transporter activity 2/984 20/18639 0.1 1.89420731707317 0.285256282311422 0.771607071735335 GO:0016408 C-acyltransferase activity 2/984 20/18639 0.1 1.89420731707317 0.285256282311422 0.771607071735335 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/984 20/18639 0.1 1.89420731707317 0.285256282311422 0.771607071735335 GO:0030742 GTP-dependent protein binding 2/984 20/18639 0.1 1.89420731707317 0.285256282311422 0.771607071735335 GO:0061608 nuclear import signal receptor activity 2/984 20/18639 0.1 1.89420731707317 0.285256282311422 0.771607071735335 GO:0141108 transporter regulator activity 11/984 170/18639 0.0647058823529412 1.22566355810617 0.287059969812716 0.774463876890556 GO:0140597 protein carrier chaperone 12/984 188/18639 0.0638297872340425 1.20906850025947 0.290702904896768 0.779414372918347 GO:0002020 protease binding 9/984 136/18639 0.0661764705882353 1.25351954806313 0.291151894130695 0.779414372918347 GO:0140789 histone phosphatase activity 9/984 136/18639 0.0661764705882353 1.25351954806313 0.291151894130695 0.779414372918347 GO:0044390 ubiquitin-like protein conjugating enzyme binding 3/984 36/18639 0.0833333333333333 1.57850609756098 0.295574098919357 0.789213315671274 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 21/984 349/18639 0.0601719197707736 1.13978090712139 0.298976521447389 0.796245954291762 GO:0032182 ubiquitin-like protein binding 8/984 120/18639 0.0666666666666667 1.26280487804878 0.300285876693254 0.797682482703106 GO:0019902 phosphatase binding 12/984 190/18639 0.0631578947368421 1.19634146341463 0.303026118070554 0.800362199953178 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/984 21/18639 0.0952380952380952 1.80400696864111 0.305157402491801 0.800362199953178 GO:0001846 opsonin binding 2/984 21/18639 0.0952380952380952 1.80400696864111 0.305157402491801 0.800362199953178 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/984 21/18639 0.0952380952380952 1.80400696864111 0.305157402491801 0.800362199953178 GO:0051428 peptide hormone receptor binding 2/984 21/18639 0.0952380952380952 1.80400696864111 0.305157402491801 0.800362199953178 GO:0140296 general transcription initiation factor binding 4/984 53/18639 0.0754716981132075 1.42959042797975 0.306241688395531 0.801177750448915 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 8/984 122/18639 0.0655737704918033 1.24210315873651 0.316013423358743 0.824506408926159 GO:0008094 ATP-dependent activity, acting on DNA 13/984 210/18639 0.0619047619047619 1.17260452961672 0.317381100610559 0.824506408926159 GO:0015485 cholesterol binding 4/984 54/18639 0.0740740740740741 1.40311653116531 0.318342242828633 0.824506408926159 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 4/984 54/18639 0.0740740740740741 1.40311653116531 0.318342242828633 0.824506408926159 GO:0004721 phosphoprotein phosphatase activity 11/984 175/18639 0.0628571428571429 1.19064459930314 0.319611917135841 0.825730539034243 GO:0000146 microfilament motor activity 3/984 38/18639 0.0789473684210526 1.49542682926829 0.324945082043355 0.831233748337509 GO:0042887 amide transmembrane transporter activity 3/984 38/18639 0.0789473684210526 1.49542682926829 0.324945082043355 0.831233748337509 GO:0008649 rRNA methyltransferase activity 2/984 22/18639 0.0909090909090909 1.7220066518847 0.324951417062443 0.831233748337509 GO:0061133 endopeptidase activator activity 2/984 22/18639 0.0909090909090909 1.7220066518847 0.324951417062443 0.831233748337509 GO:0140313 molecular sequestering activity 4/984 55/18639 0.0727272727272727 1.37760532150776 0.330478990345782 0.84329121674441 GO:0042277 peptide binding 15/984 249/18639 0.0602409638554217 1.1410887452248 0.336687506407133 0.857022743581794 GO:0099106 ion channel regulator activity 10/984 160/18639 0.0625 1.18387957317073 0.33777940688928 0.857694768473761 GO:0005319 lipid transporter activity 11/984 178/18639 0.0617977528089888 1.17057755549466 0.339532603838382 0.860038575981818 GO:0005158 insulin receptor binding 2/984 23/18639 0.0869565217391304 1.64713679745493 0.34459420088003 0.866503864348813 GO:0008171 O-methyltransferase activity 2/984 23/18639 0.0869565217391304 1.64713679745493 0.34459420088003 0.866503864348813 GO:0140102 catalytic activity, acting on a rRNA 2/984 23/18639 0.0869565217391304 1.64713679745493 0.34459420088003 0.866503864348813 GO:0003678 DNA helicase activity 5/984 74/18639 0.0675675675675676 1.27986980883322 0.352323357474857 0.879653029659746 GO:0004532 RNA exonuclease activity 3/984 40/18639 0.075 1.42065548780488 0.35431056224222 0.879653029659746 GO:0030331 nuclear estrogen receptor binding 3/984 40/18639 0.075 1.42065548780488 0.35431056224222 0.879653029659746 GO:0016504 peptidase activator activity 4/984 57/18639 0.0701754385964912 1.32926829268293 0.354809733487015 0.879653029659746 GO:0043178 alcohol binding 6/984 92/18639 0.0652173913043478 1.2353525980912 0.358129034958229 0.879653029659746 GO:0004222 metalloendopeptidase activity 7/984 110/18639 0.0636363636363636 1.20540465631929 0.361748683819572 0.879653029659746 GO:0015149 hexose transmembrane transporter activity 2/984 24/18639 0.0833333333333333 1.57850609756098 0.364046577003951 0.879653029659746 GO:0050699 WW domain binding 2/984 24/18639 0.0833333333333333 1.57850609756098 0.364046577003951 0.879653029659746 GO:0055056 D-glucose transmembrane transporter activity 2/984 24/18639 0.0833333333333333 1.57850609756098 0.364046577003951 0.879653029659746 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/984 24/18639 0.0833333333333333 1.57850609756098 0.364046577003951 0.879653029659746 GO:0070840 dynein complex binding 2/984 24/18639 0.0833333333333333 1.57850609756098 0.364046577003951 0.879653029659746 GO:0019001 guanyl nucleotide binding 23/984 400/18639 0.0575 1.08916920731707 0.366341215508989 0.879653029659746 GO:0032561 guanyl ribonucleotide binding 23/984 400/18639 0.0575 1.08916920731707 0.366341215508989 0.879653029659746 GO:0008408 3'-5' exonuclease activity 4/984 58/18639 0.0689655172413793 1.30634987384357 0.366979086866561 0.879653029659746 GO:0017116 single-stranded DNA helicase activity 4/984 58/18639 0.0689655172413793 1.30634987384357 0.366979086866561 0.879653029659746 GO:0015175 neutral L-amino acid transmembrane transporter activity 3/984 41/18639 0.0731707317073171 1.38600535395598 0.368939607575127 0.879653029659746 GO:0042287 MHC protein binding 3/984 41/18639 0.0731707317073171 1.38600535395598 0.368939607575127 0.879653029659746 GO:0140828 metal cation:monoatomic cation antiporter activity 3/984 41/18639 0.0731707317073171 1.38600535395598 0.368939607575127 0.879653029659746 GO:0016410 N-acyltransferase activity 6/984 94/18639 0.0638297872340425 1.20906850025947 0.377193525171833 0.879653029659746 GO:0015459 potassium channel regulator activity 4/984 59/18639 0.0677966101694915 1.28420835055808 0.37913537726324 0.879653029659746 GO:0001848 complement binding 2/984 25/18639 0.08 1.51536585365854 0.383273918107163 0.879653029659746 GO:0005537 D-mannose binding 2/984 25/18639 0.08 1.51536585365854 0.383273918107163 0.879653029659746 GO:0008139 nuclear localization sequence binding 2/984 25/18639 0.08 1.51536585365854 0.383273918107163 0.879653029659746 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 2/984 25/18639 0.08 1.51536585365854 0.383273918107163 0.879653029659746 GO:0017025 TBP-class protein binding 2/984 25/18639 0.08 1.51536585365854 0.383273918107163 0.879653029659746 GO:0004520 DNA endonuclease activity 3/984 42/18639 0.0714285714285714 1.35300522648084 0.383507641574955 0.879653029659746 GO:0048487 beta-tubulin binding 3/984 42/18639 0.0714285714285714 1.35300522648084 0.383507641574955 0.879653029659746 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 4/984 60/18639 0.0666666666666667 1.26280487804878 0.391267366295139 0.879653029659746 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 8/984 132/18639 0.0606060606060606 1.1480044345898 0.396398011297358 0.879653029659746 GO:0031406 carboxylic acid binding 11/984 187/18639 0.0588235294117647 1.11423959827834 0.400387595684765 0.879653029659746 GO:0005539 glycosaminoglycan binding 14/984 242/18639 0.0578512396694215 1.09582241483572 0.401412408944684 0.879653029659746 GO:0004529 DNA exonuclease activity 2/984 26/18639 0.0769230769230769 1.45708255159475 0.402245776113448 0.879653029659746 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 2/984 26/18639 0.0769230769230769 1.45708255159475 0.402245776113448 0.879653029659746 GO:0015145 monosaccharide transmembrane transporter activity 2/984 26/18639 0.0769230769230769 1.45708255159475 0.402245776113448 0.879653029659746 GO:0030507 spectrin binding 2/984 26/18639 0.0769230769230769 1.45708255159475 0.402245776113448 0.879653029659746 GO:0050750 low-density lipoprotein particle receptor binding 2/984 26/18639 0.0769230769230769 1.45708255159475 0.402245776113448 0.879653029659746 GO:0051139 metal cation:proton antiporter activity 2/984 26/18639 0.0769230769230769 1.45708255159475 0.402245776113448 0.879653029659746 GO:0070006 metalloaminopeptidase activity 2/984 26/18639 0.0769230769230769 1.45708255159475 0.402245776113448 0.879653029659746 GO:0070412 R-SMAD binding 2/984 26/18639 0.0769230769230769 1.45708255159475 0.402245776113448 0.879653029659746 GO:0120014 phospholipid transfer activity 2/984 26/18639 0.0769230769230769 1.45708255159475 0.402245776113448 0.879653029659746 GO:0033293 monocarboxylic acid binding 5/984 79/18639 0.0632911392405063 1.19886539055264 0.40537200264925 0.879653029659746 GO:0046332 SMAD binding 5/984 79/18639 0.0632911392405063 1.19886539055264 0.40537200264925 0.879653029659746 GO:0046943 carboxylic acid transmembrane transporter activity 11/984 188/18639 0.0585106382978723 1.10831279190451 0.407204158389104 0.879653029659746 GO:0001046 core promoter sequence-specific DNA binding 3/984 44/18639 0.0681818181818182 1.29150498891353 0.412391875109838 0.879653029659746 GO:0043014 alpha-tubulin binding 3/984 44/18639 0.0681818181818182 1.29150498891353 0.412391875109838 0.879653029659746 GO:0005342 organic acid transmembrane transporter activity 11/984 189/18639 0.0582010582010582 1.10244870305846 0.414024012857553 0.879653029659746 GO:0043177 organic acid binding 11/984 189/18639 0.0582010582010582 1.10244870305846 0.414024012857553 0.879653029659746 GO:0015294 solute:monoatomic cation symporter activity 7/984 116/18639 0.0603448275862069 1.14305613961312 0.414139595423501 0.879653029659746 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0004955 prostaglandin receptor activity 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0005131 growth hormone receptor binding 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0008140 cAMP response element binding protein binding 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0015187 glycine transmembrane transporter activity 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0016868 intramolecular phosphotransferase activity 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0032052 bile acid binding 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0032356 oxidized DNA binding 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0033204 ribonuclease P RNA binding 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0042975 peroxisome proliferator activated receptor binding 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0097177 mitochondrial ribosome binding 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0140135 mechanosensitive monoatomic cation channel activity 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0140940 histone H2A methyltransferase activity 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0141109 transporter activator activity 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:1990259 histone H2AQ104 methyltransferase activity 1/984 10/18639 0.1 1.89420731707317 0.418710234764242 0.879653029659746 GO:0015297 antiporter activity 8/984 135/18639 0.0592592592592593 1.12249322493225 0.420725530355289 0.879653029659746 GO:0005385 zinc ion transmembrane transporter activity 2/984 27/18639 0.0740740740740741 1.40311653116531 0.420935538196356 0.879653029659746 GO:0008395 steroid hydroxylase activity 2/984 27/18639 0.0740740740740741 1.40311653116531 0.420935538196356 0.879653029659746 GO:0008201 heparin binding 10/984 172/18639 0.0581395348837209 1.10128332387975 0.423447744410851 0.879653029659746 GO:0005507 copper ion binding 4/984 63/18639 0.0634920634920635 1.20267131242741 0.427411922284468 0.879653029659746 GO:0004386 helicase activity 9/984 155/18639 0.0580645161290323 1.09986231313926 0.433701304104595 0.879653029659746 GO:0046875 ephrin receptor binding 2/984 28/18639 0.0714285714285714 1.35300522648084 0.439320107392997 0.879653029659746 GO:0051119 sugar transmembrane transporter activity 2/984 28/18639 0.0714285714285714 1.35300522648084 0.439320107392997 0.879653029659746 GO:0004536 DNA nuclease activity 4/984 64/18639 0.0625 1.18387957317073 0.439343394584423 0.879653029659746 GO:0030291 protein serine/threonine kinase inhibitor activity 3/984 46/18639 0.0652173913043478 1.2353525980912 0.440836747216069 0.879653029659746 GO:0000099 sulfur amino acid transmembrane transporter activity 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0002162 dystroglycan binding 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0004954 prostanoid receptor activity 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0008271 secondary active sulfate transmembrane transporter activity 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0008432 JUN kinase binding 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0008526 phosphatidylinositol transfer activity 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0015173 aromatic amino acid transmembrane transporter activity 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0015217 ADP transmembrane transporter activity 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0016594 glycine binding 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0019206 nucleoside kinase activity 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0034056 estrogen response element binding 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0034713 type I transforming growth factor beta receptor binding 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0042608 T cell receptor binding 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0045294 alpha-catenin binding 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0047676 arachidonate-CoA ligase activity 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0048185 activin binding 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0070697 activin receptor binding 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0140537 transcription regulator activator activity 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0180030 inositol phosphate kinase activity 1/984 11/18639 0.0909090909090909 1.7220066518847 0.449414466284559 0.879653029659746 GO:0061749 forked DNA-dependent helicase activity 3/984 47/18639 0.0638297872340425 1.20906850025947 0.454859603710547 0.879653029659746 GO:0140359 ABC-type transporter activity 3/984 47/18639 0.0638297872340425 1.20906850025947 0.454859603710547 0.879653029659746 GO:1990518 single-stranded 3'-5' DNA helicase activity 3/984 47/18639 0.0638297872340425 1.20906850025947 0.454859603710547 0.879653029659746 GO:0140658 ATP-dependent chromatin remodeler activity 9/984 158/18639 0.0569620253164557 1.07897885149738 0.456411124720645 0.879653029659746 GO:0004629 phospholipase C activity 2/984 29/18639 0.0689655172413793 1.30634987384357 0.457379606196557 0.879653029659746 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/984 29/18639 0.0689655172413793 1.30634987384357 0.457379606196557 0.879653029659746 GO:0051861 glycolipid binding 2/984 29/18639 0.0689655172413793 1.30634987384357 0.457379606196557 0.879653029659746 GO:0004540 RNA nuclease activity 7/984 121/18639 0.0578512396694215 1.09582241483572 0.457583652168116 0.879653029659746 GO:0009378 four-way junction helicase activity 3/984 48/18639 0.0625 1.18387957317073 0.468732902511751 0.879653029659746 GO:0036121 double-stranded DNA helicase activity 3/984 48/18639 0.0625 1.18387957317073 0.468732902511751 0.879653029659746 GO:0043138 3'-5' DNA helicase activity 3/984 48/18639 0.0625 1.18387957317073 0.468732902511751 0.879653029659746 GO:0003689 DNA clamp loader activity 9/984 160/18639 0.05625 1.06549161585366 0.471470821957146 0.879653029659746 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/984 67/18639 0.0597014925373134 1.13087004004368 0.47466235626896 0.879653029659746 GO:0001968 fibronectin binding 2/984 30/18639 0.0666666666666667 1.26280487804878 0.475097101595278 0.879653029659746 GO:0033612 receptor serine/threonine kinase binding 2/984 30/18639 0.0666666666666667 1.26280487804878 0.475097101595278 0.879653029659746 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0003720 telomerase activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0003995 acyl-CoA dehydrogenase activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0004000 adenosine deaminase activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0004032 aldose reductase (NADPH) activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0004126 cytidine deaminase activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0004526 ribonuclease P activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0004859 phospholipase inhibitor activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0004875 complement receptor activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0005095 GTPase inhibitor activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0005165 neurotrophin receptor binding 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0008179 adenylate cyclase binding 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0008603 cAMP-dependent protein kinase regulator activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0016208 AMP binding 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0016801 hydrolase activity, acting on ether bonds 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0016803 ether hydrolase activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0031543 peptidyl-proline dioxygenase activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0035251 UDP-glucosyltransferase activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0036009 protein-glutamine N-methyltransferase activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0042301 phosphate ion binding 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0045295 gamma-catenin binding 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0097677 STAT family protein binding 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0140900 chloride:bicarbonate antiporter activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:1990817 poly(A) RNA polymerase activity 1/984 12/18639 0.0833333333333333 1.57850609756098 0.478498434782303 0.879653029659746 GO:0001222 transcription corepressor binding 3/984 49/18639 0.0612244897959184 1.159718765555 0.482445500719255 0.879653029659746 GO:0016763 pentosyltransferase activity 3/984 49/18639 0.0612244897959184 1.159718765555 0.482445500719255 0.879653029659746 GO:0003924 GTPase activity 18/984 331/18639 0.054380664652568 1.03008252892197 0.483143269275821 0.879653029659746 GO:1901681 sulfur compound binding 15/984 275/18639 0.0545454545454545 1.03320399113082 0.486130703135109 0.879653029659746 GO:0003777 microtubule motor activity 4/984 68/18639 0.0588235294117647 1.11423959827834 0.48625007750035 0.879653029659746 GO:0005548 phospholipid transporter activity 4/984 68/18639 0.0588235294117647 1.11423959827834 0.48625007750035 0.879653029659746 GO:0032934 sterol binding 4/984 68/18639 0.0588235294117647 1.11423959827834 0.48625007750035 0.879653029659746 GO:0140223 general transcription initiation factor activity 4/984 68/18639 0.0588235294117647 1.11423959827834 0.48625007750035 0.879653029659746 GO:0000149 SNARE binding 6/984 106/18639 0.0566037735849057 1.07219282098481 0.490472894546511 0.879653029659746 GO:0005164 tumor necrosis factor receptor binding 2/984 31/18639 0.0645161290322581 1.2220692368214 0.492458350123146 0.879653029659746 GO:0005310 dicarboxylic acid transmembrane transporter activity 2/984 31/18639 0.0645161290322581 1.2220692368214 0.492458350123146 0.879653029659746 GO:0005452 solute:inorganic anion antiporter activity 2/984 31/18639 0.0645161290322581 1.2220692368214 0.492458350123146 0.879653029659746 GO:0008327 methyl-CpG binding 2/984 31/18639 0.0645161290322581 1.2220692368214 0.492458350123146 0.879653029659746 GO:0070325 lipoprotein particle receptor binding 2/984 31/18639 0.0645161290322581 1.2220692368214 0.492458350123146 0.879653029659746 GO:0072349 modified amino acid transmembrane transporter activity 2/984 31/18639 0.0645161290322581 1.2220692368214 0.492458350123146 0.879653029659746 GO:0005007 fibroblast growth factor receptor activity 3/984 50/18639 0.06 1.1365243902439 0.495987203476354 0.879653029659746 GO:0032813 tumor necrosis factor receptor superfamily binding 3/984 50/18639 0.06 1.1365243902439 0.495987203476354 0.879653029659746 GO:0002039 p53 binding 4/984 69/18639 0.0579710144927536 1.09809119830329 0.497732904807056 0.879653029659746 GO:0008080 N-acetyltransferase activity 4/984 69/18639 0.0579710144927536 1.09809119830329 0.497732904807056 0.879653029659746 GO:0004197 cysteine-type endopeptidase activity 5/984 88/18639 0.0568181818181818 1.07625415742794 0.498850021361001 0.879653029659746 GO:0140713 histone chaperone activity 9/984 164/18639 0.0548780487804878 1.03950401546698 0.501308956864251 0.879653029659746 GO:0003964 RNA-directed DNA polymerase activity 1/984 13/18639 0.0769230769230769 1.45708255159475 0.506047559180984 0.879653029659746 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/984 13/18639 0.0769230769230769 1.45708255159475 0.506047559180984 0.879653029659746 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/984 13/18639 0.0769230769230769 1.45708255159475 0.506047559180984 0.879653029659746 GO:0019104 DNA N-glycosylase activity 1/984 13/18639 0.0769230769230769 1.45708255159475 0.506047559180984 0.879653029659746 GO:0031994 insulin-like growth factor I binding 1/984 13/18639 0.0769230769230769 1.45708255159475 0.506047559180984 0.879653029659746 GO:0035673 oligopeptide transmembrane transporter activity 1/984 13/18639 0.0769230769230769 1.45708255159475 0.506047559180984 0.879653029659746 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/984 13/18639 0.0769230769230769 1.45708255159475 0.506047559180984 0.879653029659746 GO:0070700 BMP receptor binding 1/984 13/18639 0.0769230769230769 1.45708255159475 0.506047559180984 0.879653029659746 GO:0071837 HMG box domain binding 1/984 13/18639 0.0769230769230769 1.45708255159475 0.506047559180984 0.879653029659746 GO:0097157 pre-mRNA intronic binding 1/984 13/18639 0.0769230769230769 1.45708255159475 0.506047559180984 0.879653029659746 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/984 13/18639 0.0769230769230769 1.45708255159475 0.506047559180984 0.879653029659746 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/984 13/18639 0.0769230769230769 1.45708255159475 0.506047559180984 0.879653029659746 GO:0008237 metallopeptidase activity 10/984 184/18639 0.0543478260869565 1.02946049840933 0.508712885991092 0.879653029659746 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 5/984 89/18639 0.0561797752808989 1.06416141408605 0.508920290149338 0.879653029659746 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 5/984 89/18639 0.0561797752808989 1.06416141408605 0.508920290149338 0.879653029659746 GO:0030544 Hsp70 protein binding 3/984 51/18639 0.0588235294117647 1.11423959827834 0.509348729005958 0.879653029659746 GO:0015106 bicarbonate transmembrane transporter activity 2/984 32/18639 0.0625 1.18387957317073 0.509451561579003 0.879653029659746 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/984 32/18639 0.0625 1.18387957317073 0.509451561579003 0.879653029659746 GO:0043425 bHLH transcription factor binding 2/984 32/18639 0.0625 1.18387957317073 0.509451561579003 0.879653029659746 GO:0051059 NF-kappaB binding 2/984 32/18639 0.0625 1.18387957317073 0.509451561579003 0.879653029659746 GO:0071813 lipoprotein particle binding 2/984 32/18639 0.0625 1.18387957317073 0.509451561579003 0.879653029659746 GO:0071814 protein-lipid complex binding 2/984 32/18639 0.0625 1.18387957317073 0.509451561579003 0.879653029659746 GO:0004620 phospholipase activity 6/984 109/18639 0.055045871559633 1.04268292682927 0.517874091559324 0.890955828455968 GO:0140793 histone H2AXY142 phosphatase activity 5/984 90/18639 0.0555555555555556 1.05233739837398 0.518907972195515 0.890955828455968 GO:0003730 mRNA 3'-UTR binding 14/984 262/18639 0.0534351145038168 1.01217184881772 0.520637133763684 0.890955828455968 GO:0005080 protein kinase C binding 3/984 52/18639 0.0576923076923077 1.09281191369606 0.52252167290655 0.890955828455968 GO:0019239 deaminase activity 2/984 33/18639 0.0606060606060606 1.1480044345898 0.526067180156652 0.890955828455968 GO:0019956 chemokine binding 2/984 33/18639 0.0606060606060606 1.1480044345898 0.526067180156652 0.890955828455968 GO:0140311 protein sequestering activity 2/984 33/18639 0.0606060606060606 1.1480044345898 0.526067180156652 0.890955828455968 GO:0140416 transcription regulator inhibitor activity 2/984 33/18639 0.0606060606060606 1.1480044345898 0.526067180156652 0.890955828455968 GO:0008234 cysteine-type peptidase activity 10/984 187/18639 0.053475935828877 1.01294508934394 0.529524366752999 0.890955828455968 GO:0005347 ATP transmembrane transporter activity 1/984 14/18639 0.0714285714285714 1.35300522648084 0.532142759533497 0.890955828455968 GO:0019992 diacylglycerol binding 1/984 14/18639 0.0714285714285714 1.35300522648084 0.532142759533497 0.890955828455968 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/984 14/18639 0.0714285714285714 1.35300522648084 0.532142759533497 0.890955828455968 GO:0032454 histone H3K9 demethylase activity 1/984 14/18639 0.0714285714285714 1.35300522648084 0.532142759533497 0.890955828455968 GO:0034236 protein kinase A catalytic subunit binding 1/984 14/18639 0.0714285714285714 1.35300522648084 0.532142759533497 0.890955828455968 GO:1901612 cardiolipin binding 1/984 14/18639 0.0714285714285714 1.35300522648084 0.532142759533497 0.890955828455968 GO:0016251 RNA polymerase II general transcription initiation factor activity 3/984 53/18639 0.0566037735849057 1.07219282098481 0.535498471977211 0.890955828455968 GO:0034212 protein N-acetyltransferase activity 3/984 53/18639 0.0566037735849057 1.07219282098481 0.535498471977211 0.890955828455968 GO:1901505 carbohydrate derivative transmembrane transporter activity 3/984 53/18639 0.0566037735849057 1.07219282098481 0.535498471977211 0.890955828455968 GO:0052689 carboxylic ester hydrolase activity 5/984 92/18639 0.0543478260869565 1.02946049840933 0.538617705133412 0.890955828455968 GO:0008376 acetylgalactosaminyltransferase activity 2/984 34/18639 0.0588235294117647 1.11423959827834 0.542297681809029 0.890955828455968 GO:0004521 RNA endonuclease activity 4/984 73/18639 0.0547945205479452 1.03792181757434 0.542487917604732 0.890955828455968 GO:0000510 H3-H4 histone complex chaperone activity 8/984 151/18639 0.0529801324503311 1.00355354546923 0.547319613909763 0.890955828455968 GO:0140584 chromatin extrusion motor activity 8/984 151/18639 0.0529801324503311 1.00355354546923 0.547319613909763 0.890955828455968 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 8/984 151/18639 0.0529801324503311 1.00355354546923 0.547319613909763 0.890955828455968 GO:0140849 ATP-dependent H2AZ histone chaperone activity 8/984 151/18639 0.0529801324503311 1.00355354546923 0.547319613909763 0.890955828455968 GO:0050661 NADP binding 3/984 54/18639 0.0555555555555556 1.05233739837398 0.54827236780948 0.890955828455968 GO:0016757 glycosyltransferase activity 14/984 267/18639 0.052434456928839 0.993217319813648 0.54960533977581 0.890955828455968 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 12/984 229/18639 0.0524017467248908 0.992597720737033 0.552713693414636 0.890955828455968 GO:0015616 DNA translocase activity 8/984 152/18639 0.0526315789473684 0.996951219512195 0.554897928359074 0.890955828455968 GO:0140674 ATP-dependent histone chaperone activity 8/984 152/18639 0.0526315789473684 0.996951219512195 0.554897928359074 0.890955828455968 GO:0004089 carbonate dehydratase activity 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0004467 long-chain fatty acid-CoA ligase activity 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0004953 icosanoid receptor activity 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0008242 omega peptidase activity 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0010181 FMN binding 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0015116 sulfate transmembrane transporter activity 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0017081 chloride channel regulator activity 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0034483 heparan sulfate sulfotransferase activity 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0050700 CARD domain binding 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0050780 dopamine receptor binding 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0061578 K63-linked deubiquitinase activity 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0120283 protein serine/threonine kinase binding 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0140776 protein-containing complex destabilizing activity 1/984 15/18639 0.0666666666666667 1.26280487804878 0.55686069374123 0.890955828455968 GO:0000175 3'-5'-RNA exonuclease activity 2/984 35/18639 0.0571428571428571 1.08240418118467 0.558137386745099 0.890955828455968 GO:0034061 DNA polymerase activity 2/984 35/18639 0.0571428571428571 1.08240418118467 0.558137386745099 0.890955828455968 GO:0061775 cohesin loader activity 8/984 153/18639 0.0522875816993464 0.990435198469632 0.562422689422086 0.891579289812172 GO:0019003 GDP binding 4/984 75/18639 0.0533333333333333 1.01024390243902 0.564082304811441 0.891579289812172 GO:0004175 endopeptidase activity 21/984 405/18639 0.0518518518518519 0.982181571815718 0.56619984232015 0.891579289812172 GO:0008276 protein methyltransferase activity 5/984 95/18639 0.0526315789473684 0.996951219512195 0.567457610201639 0.891579289812172 GO:0035401 histone H3Y41 kinase activity 6/984 115/18639 0.0521739130434783 0.988282078472959 0.57081671796672 0.891579289812172 GO:0140801 histone H2AXY142 kinase activity 6/984 115/18639 0.0521739130434783 0.988282078472959 0.57081671796672 0.891579289812172 GO:0000062 fatty-acyl-CoA binding 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0004708 MAP kinase kinase activity 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0005149 interleukin-1 receptor binding 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0008296 3'-5'-DNA exonuclease activity 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0015385 sodium:proton antiporter activity 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0015562 efflux transmembrane transporter activity 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0019841 retinol binding 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0022841 potassium ion leak channel activity 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0022858 alanine transmembrane transporter activity 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0034450 ubiquitin-ubiquitin ligase activity 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0043023 ribosomal large subunit binding 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0055102 lipase inhibitor activity 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0140328 floppase activity 1/984 16/18639 0.0625 1.18387957317073 0.580273981829645 0.891579289812172 GO:0016779 nucleotidyltransferase activity 7/984 136/18639 0.0514705882352941 0.974959648493544 0.581988653258143 0.891579289812172 GO:0019838 growth factor binding 7/984 136/18639 0.0514705882352941 0.974959648493544 0.581988653258143 0.891579289812172 GO:0016791 phosphatase activity 14/984 273/18639 0.0512820512820513 0.971388367729831 0.58353870306376 0.891579289812172 GO:0015932 nucleobase-containing compound transmembrane transporter activity 3/984 57/18639 0.0526315789473684 0.996951219512195 0.585320359887359 0.891579289812172 GO:0004252 serine-type endopeptidase activity 9/984 176/18639 0.0511363636363636 0.968628741685144 0.587321541909831 0.891579289812172 GO:1990782 protein tyrosine kinase binding 6/984 117/18639 0.0512820512820513 0.971388367729831 0.587822174923116 0.891579289812172 GO:0022829 wide pore channel activity 2/984 37/18639 0.0540540540540541 1.02389584706658 0.588629881317157 0.891579289812172 GO:0030551 cyclic nucleotide binding 2/984 37/18639 0.0540540540540541 1.02389584706658 0.588629881317157 0.891579289812172 GO:0042805 actinin binding 2/984 37/18639 0.0540540540540541 1.02389584706658 0.588629881317157 0.891579289812172 GO:0043394 proteoglycan binding 2/984 37/18639 0.0540540540540541 1.02389584706658 0.588629881317157 0.891579289812172 GO:0004725 protein tyrosine phosphatase activity 5/984 98/18639 0.0510204081632653 0.966432304629169 0.595343715059401 0.891579289812172 GO:0016758 hexosyltransferase activity 10/984 197/18639 0.050761421319797 0.961526556889934 0.596459577371895 0.891579289812172 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/984 17/18639 0.0588235294117647 1.11423959827834 0.602451418433824 0.891579289812172 GO:0004549 tRNA-specific ribonuclease activity 1/984 17/18639 0.0588235294117647 1.11423959827834 0.602451418433824 0.891579289812172 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/984 17/18639 0.0588235294117647 1.11423959827834 0.602451418433824 0.891579289812172 GO:0005092 GDP-dissociation inhibitor activity 1/984 17/18639 0.0588235294117647 1.11423959827834 0.602451418433824 0.891579289812172 GO:0008429 phosphatidylethanolamine binding 1/984 17/18639 0.0588235294117647 1.11423959827834 0.602451418433824 0.891579289812172 GO:0015278 intracellularly gated calcium channel activity 1/984 17/18639 0.0588235294117647 1.11423959827834 0.602451418433824 0.891579289812172 GO:0030169 low-density lipoprotein particle binding 1/984 17/18639 0.0588235294117647 1.11423959827834 0.602451418433824 0.891579289812172 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/984 17/18639 0.0588235294117647 1.11423959827834 0.602451418433824 0.891579289812172 GO:0031489 myosin V binding 1/984 17/18639 0.0588235294117647 1.11423959827834 0.602451418433824 0.891579289812172 GO:0032183 SUMO binding 1/984 17/18639 0.0588235294117647 1.11423959827834 0.602451418433824 0.891579289812172 GO:0036041 long-chain fatty acid binding 1/984 17/18639 0.0588235294117647 1.11423959827834 0.602451418433824 0.891579289812172 GO:0048038 quinone binding 1/984 17/18639 0.0588235294117647 1.11423959827834 0.602451418433824 0.891579289812172 GO:1901567 fatty acid derivative binding 1/984 17/18639 0.0588235294117647 1.11423959827834 0.602451418433824 0.891579289812172 GO:0005109 frizzled binding 2/984 38/18639 0.0526315789473684 0.996951219512195 0.603279036832368 0.891579289812172 GO:0005501 retinoid binding 2/984 38/18639 0.0526315789473684 0.996951219512195 0.603279036832368 0.891579289812172 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 2/984 38/18639 0.0526315789473684 0.996951219512195 0.603279036832368 0.891579289812172 GO:0019840 isoprenoid binding 2/984 38/18639 0.0526315789473684 0.996951219512195 0.603279036832368 0.891579289812172 GO:0001786 phosphatidylserine binding 3/984 59/18639 0.0508474576271186 0.963156262918561 0.608913518152833 0.896071597736271 GO:0004879 nuclear receptor activity 3/984 59/18639 0.0508474576271186 0.963156262918561 0.608913518152833 0.896071597736271 GO:0070063 RNA polymerase binding 3/984 59/18639 0.0508474576271186 0.963156262918561 0.608913518152833 0.896071597736271 GO:0004713 protein tyrosine kinase activity 7/984 140/18639 0.05 0.947103658536585 0.61278706576672 0.900492766147975 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/984 60/18639 0.05 0.947103658536585 0.620368578776922 0.902098698856513 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 3/984 60/18639 0.05 0.947103658536585 0.620368578776922 0.902098698856513 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/984 60/18639 0.05 0.947103658536585 0.620368578776922 0.902098698856513 GO:0098531 ligand-modulated transcription factor activity 3/984 60/18639 0.05 0.947103658536585 0.620368578776922 0.902098698856513 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 9/984 181/18639 0.0497237569060773 0.941871041638593 0.621066057556546 0.902098698856513 GO:0008409 5'-3' exonuclease activity 1/984 18/18639 0.0555555555555556 1.05233739837398 0.623458174113188 0.902098698856513 GO:0016854 racemase and epimerase activity 1/984 18/18639 0.0555555555555556 1.05233739837398 0.623458174113188 0.902098698856513 GO:0017128 phospholipid scramblase activity 1/984 18/18639 0.0555555555555556 1.05233739837398 0.623458174113188 0.902098698856513 GO:0035615 clathrin adaptor activity 1/984 18/18639 0.0555555555555556 1.05233739837398 0.623458174113188 0.902098698856513 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/984 18/18639 0.0555555555555556 1.05233739837398 0.623458174113188 0.902098698856513 GO:0070064 proline-rich region binding 1/984 18/18639 0.0555555555555556 1.05233739837398 0.623458174113188 0.902098698856513 GO:0030971 receptor tyrosine kinase binding 4/984 81/18639 0.0493827160493827 0.935411020776874 0.625325551401131 0.903538732568441 GO:0008083 growth factor activity 8/984 162/18639 0.0493827160493827 0.935411020776874 0.627432157202344 0.903771112768146 GO:0015171 amino acid transmembrane transporter activity 5/984 102/18639 0.0490196078431373 0.92853299856528 0.630909608495244 0.903771112768146 GO:0004177 aminopeptidase activity 2/984 40/18639 0.05 0.947103658536585 0.631383489071901 0.903771112768146 GO:0015144 carbohydrate transmembrane transporter activity 2/984 40/18639 0.05 0.947103658536585 0.631383489071901 0.903771112768146 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/984 40/18639 0.05 0.947103658536585 0.631383489071901 0.903771112768146 GO:0071855 neuropeptide receptor binding 2/984 40/18639 0.05 0.947103658536585 0.631383489071901 0.903771112768146 GO:0019905 syntaxin binding 3/984 61/18639 0.0491803278688525 0.931577369052379 0.631592939810944 0.903771112768146 GO:0042578 phosphoric ester hydrolase activity 18/984 363/18639 0.0495867768595041 0.939276355573473 0.642457699175973 0.905593480409006 GO:0015179 L-amino acid transmembrane transporter activity 3/984 62/18639 0.0483870967741935 0.91655192761605 0.642585000721385 0.905593480409006 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/984 19/18639 0.0526315789473684 0.996951219512195 0.643355986082074 0.905593480409006 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/984 19/18639 0.0526315789473684 0.996951219512195 0.643355986082074 0.905593480409006 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/984 19/18639 0.0526315789473684 0.996951219512195 0.643355986082074 0.905593480409006 GO:0005520 insulin-like growth factor binding 1/984 19/18639 0.0526315789473684 0.996951219512195 0.643355986082074 0.905593480409006 GO:0008574 plus-end-directed microtubule motor activity 1/984 19/18639 0.0526315789473684 0.996951219512195 0.643355986082074 0.905593480409006 GO:0016918 retinal binding 1/984 19/18639 0.0526315789473684 0.996951219512195 0.643355986082074 0.905593480409006 GO:0042800 histone H3K4 methyltransferase activity 1/984 19/18639 0.0526315789473684 0.996951219512195 0.643355986082074 0.905593480409006 GO:0046527 glucosyltransferase activity 1/984 19/18639 0.0526315789473684 0.996951219512195 0.643355986082074 0.905593480409006 GO:0120227 acyl-CoA binding 1/984 19/18639 0.0526315789473684 0.996951219512195 0.643355986082074 0.905593480409006 GO:0140036 ubiquitin-modified protein reader activity 1/984 19/18639 0.0526315789473684 0.996951219512195 0.643355986082074 0.905593480409006 GO:0001540 amyloid-beta binding 4/984 83/18639 0.0481927710843374 0.912870996179841 0.644480469284541 0.905945408655066 GO:0005516 calmodulin binding 10/984 207/18639 0.0483091787439614 0.915075998586073 0.658581716507459 0.923341398536937 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/984 20/18639 0.05 0.947103658536585 0.662203338912108 0.923341398536937 GO:0015095 magnesium ion transmembrane transporter activity 1/984 20/18639 0.05 0.947103658536585 0.662203338912108 0.923341398536937 GO:0016004 phospholipase activator activity 1/984 20/18639 0.05 0.947103658536585 0.662203338912108 0.923341398536937 GO:0031418 L-ascorbic acid binding 1/984 20/18639 0.05 0.947103658536585 0.662203338912108 0.923341398536937 GO:0052745 inositol phosphate phosphatase activity 1/984 20/18639 0.05 0.947103658536585 0.662203338912108 0.923341398536937 GO:0019783 ubiquitin-like protein peptidase activity 6/984 127/18639 0.047244094488189 0.894901094680238 0.667204108692498 0.923629492917101 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/984 86/18639 0.0465116279069767 0.8810266591038 0.671978664415116 0.923629492917101 GO:0038024 cargo receptor activity 3/984 65/18639 0.0461538461538462 0.874249530956848 0.674158598689746 0.923629492917101 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/984 21/18639 0.0476190476190476 0.902003484320557 0.680055635733124 0.923629492917101 GO:0008373 sialyltransferase activity 1/984 21/18639 0.0476190476190476 0.902003484320557 0.680055635733124 0.923629492917101 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/984 21/18639 0.0476190476190476 0.902003484320557 0.680055635733124 0.923629492917101 GO:0009975 cyclase activity 1/984 21/18639 0.0476190476190476 0.902003484320557 0.680055635733124 0.923629492917101 GO:0019200 carbohydrate kinase activity 1/984 21/18639 0.0476190476190476 0.902003484320557 0.680055635733124 0.923629492917101 GO:0036122 BMP binding 1/984 21/18639 0.0476190476190476 0.902003484320557 0.680055635733124 0.923629492917101 GO:0051010 microtubule plus-end binding 1/984 21/18639 0.0476190476190476 0.902003484320557 0.680055635733124 0.923629492917101 GO:0061891 calcium ion sensor activity 1/984 21/18639 0.0476190476190476 0.902003484320557 0.680055635733124 0.923629492917101 GO:0140312 cargo adaptor activity 1/984 21/18639 0.0476190476190476 0.902003484320557 0.680055635733124 0.923629492917101 GO:1904047 S-adenosyl-L-methionine binding 1/984 21/18639 0.0476190476190476 0.902003484320557 0.680055635733124 0.923629492917101 GO:0005496 steroid binding 5/984 108/18639 0.0462962962962963 0.87694783197832 0.680537948448546 0.923629492917101 GO:0008081 phosphoric diester hydrolase activity 4/984 87/18639 0.0459770114942529 0.870899915895711 0.680811277490006 0.923629492917101 GO:0001223 transcription coactivator binding 2/984 44/18639 0.0454545454545455 0.86100332594235 0.682882523645172 0.923629492917101 GO:0030547 signaling receptor inhibitor activity 2/984 44/18639 0.0454545454545455 0.86100332594235 0.682882523645172 0.923629492917101 GO:0016298 lipase activity 6/984 130/18639 0.0461538461538462 0.874249530956848 0.689031839687283 0.923629492917101 GO:0008173 RNA methyltransferase activity 3/984 67/18639 0.0447761194029851 0.848152530032763 0.694037645473222 0.923629492917101 GO:0016500 protein-hormone receptor activity 3/984 67/18639 0.0447761194029851 0.848152530032763 0.694037645473222 0.923629492917101 GO:0042054 histone methyltransferase activity 3/984 67/18639 0.0447761194029851 0.848152530032763 0.694037645473222 0.923629492917101 GO:0050840 extracellular matrix binding 3/984 67/18639 0.0447761194029851 0.848152530032763 0.694037645473222 0.923629492917101 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/984 45/18639 0.0444444444444444 0.841869918699187 0.694799084842925 0.923629492917101 GO:0046915 transition metal ion transmembrane transporter activity 2/984 45/18639 0.0444444444444444 0.841869918699187 0.694799084842925 0.923629492917101 GO:0140303 intramembrane lipid transporter activity 2/984 45/18639 0.0444444444444444 0.841869918699187 0.694799084842925 0.923629492917101 GO:0051020 GTPase binding 15/984 315/18639 0.0476190476190476 0.902003484320557 0.69660081165867 0.923629492917101 GO:0008093 cytoskeletal anchor activity 1/984 22/18639 0.0454545454545455 0.86100332594235 0.696965360431727 0.923629492917101 GO:0016881 acid-amino acid ligase activity 1/984 22/18639 0.0454545454545455 0.86100332594235 0.696965360431727 0.923629492917101 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/984 22/18639 0.0454545454545455 0.86100332594235 0.696965360431727 0.923629492917101 GO:0031683 G-protein beta/gamma-subunit complex binding 1/984 22/18639 0.0454545454545455 0.86100332594235 0.696965360431727 0.923629492917101 GO:0034062 5'-3' RNA polymerase activity 1/984 22/18639 0.0454545454545455 0.86100332594235 0.696965360431727 0.923629492917101 GO:0097747 RNA polymerase activity 1/984 22/18639 0.0454545454545455 0.86100332594235 0.696965360431727 0.923629492917101 GO:0140035 ubiquitin-like protein reader activity 1/984 22/18639 0.0454545454545455 0.86100332594235 0.696965360431727 0.923629492917101 GO:0140784 metal ion sensor activity 1/984 22/18639 0.0454545454545455 0.86100332594235 0.696965360431727 0.923629492917101 GO:0005126 cytokine receptor binding 13/984 275/18639 0.0472727272727273 0.895443458980044 0.698458728361527 0.923629492917101 GO:0008236 serine-type peptidase activity 9/984 194/18639 0.0463917525773196 0.878755971838069 0.701508934375667 0.923629492917101 GO:0000295 adenine nucleotide transmembrane transporter activity 1/984 23/18639 0.0434782608695652 0.823568398727465 0.712982231320441 0.923629492917101 GO:0003887 DNA-directed DNA polymerase activity 1/984 23/18639 0.0434782608695652 0.823568398727465 0.712982231320441 0.923629492917101 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/984 23/18639 0.0434782608695652 0.823568398727465 0.712982231320441 0.923629492917101 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/984 23/18639 0.0434782608695652 0.823568398727465 0.712982231320441 0.923629492917101 GO:0016493 C-C chemokine receptor activity 1/984 23/18639 0.0434782608695652 0.823568398727465 0.712982231320441 0.923629492917101 GO:0031681 G-protein beta-subunit binding 1/984 23/18639 0.0434782608695652 0.823568398727465 0.712982231320441 0.923629492917101 GO:0042171 lysophosphatidic acid acyltransferase activity 1/984 23/18639 0.0434782608695652 0.823568398727465 0.712982231320441 0.923629492917101 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/984 23/18639 0.0434782608695652 0.823568398727465 0.712982231320441 0.923629492917101 GO:0071617 lysophospholipid acyltransferase activity 1/984 23/18639 0.0434782608695652 0.823568398727465 0.712982231320441 0.923629492917101 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/984 23/18639 0.0434782608695652 0.823568398727465 0.712982231320441 0.923629492917101 GO:0061733 protein-lysine-acetyltransferase activity 2/984 47/18639 0.0425531914893617 0.806045666839647 0.717519859629073 0.923629492917101 GO:0140938 histone H3 methyltransferase activity 2/984 47/18639 0.0425531914893617 0.806045666839647 0.717519859629073 0.923629492917101 GO:0017171 serine hydrolase activity 9/984 198/18639 0.0454545454545455 0.86100332594235 0.72394075463543 0.923629492917101 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/984 24/18639 0.0416666666666667 0.789253048780488 0.728153346725506 0.923629492917101 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/984 24/18639 0.0416666666666667 0.789253048780488 0.728153346725506 0.923629492917101 GO:0004622 lysophospholipase activity 1/984 24/18639 0.0416666666666667 0.789253048780488 0.728153346725506 0.923629492917101 GO:0005315 phosphate transmembrane transporter activity 1/984 24/18639 0.0416666666666667 0.789253048780488 0.728153346725506 0.923629492917101 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/984 24/18639 0.0416666666666667 0.789253048780488 0.728153346725506 0.923629492917101 GO:0019957 C-C chemokine binding 1/984 24/18639 0.0416666666666667 0.789253048780488 0.728153346725506 0.923629492917101 GO:0030215 semaphorin receptor binding 1/984 24/18639 0.0416666666666667 0.789253048780488 0.728153346725506 0.923629492917101 GO:0030552 cAMP binding 1/984 24/18639 0.0416666666666667 0.789253048780488 0.728153346725506 0.923629492917101 GO:0035035 histone acetyltransferase binding 1/984 24/18639 0.0416666666666667 0.789253048780488 0.728153346725506 0.923629492917101 GO:0050431 transforming growth factor beta binding 1/984 24/18639 0.0416666666666667 0.789253048780488 0.728153346725506 0.923629492917101 GO:0060229 lipase activator activity 1/984 24/18639 0.0416666666666667 0.789253048780488 0.728153346725506 0.923629492917101 GO:0070300 phosphatidic acid binding 1/984 24/18639 0.0416666666666667 0.789253048780488 0.728153346725506 0.923629492917101 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/984 48/18639 0.0416666666666667 0.789253048780488 0.728336683851565 0.923629492917101 GO:0140693 molecular condensate scaffold activity 2/984 48/18639 0.0416666666666667 0.789253048780488 0.728336683851565 0.923629492917101 GO:0051213 dioxygenase activity 4/984 93/18639 0.043010752688172 0.8147128245476 0.730280735632285 0.923629492917101 GO:0140299 molecular sensor activity 3/984 71/18639 0.0422535211267606 0.800369288904157 0.731016869311987 0.923629492917101 GO:0101005 deubiquitinase activity 5/984 115/18639 0.0434782608695652 0.823568398727465 0.732519031161479 0.923629492917101 GO:0042562 hormone binding 4/984 94/18639 0.0425531914893617 0.806045666839647 0.737940060678068 0.923629492917101 GO:0005004 GPI-linked ephrin receptor activity 2/984 49/18639 0.0408163265306122 0.773145843703335 0.73880013845294 0.923629492917101 GO:0005008 hepatocyte growth factor receptor activity 2/984 49/18639 0.0408163265306122 0.773145843703335 0.73880013845294 0.923629492917101 GO:0005009 insulin receptor activity 2/984 49/18639 0.0408163265306122 0.773145843703335 0.73880013845294 0.923629492917101 GO:0005011 macrophage colony-stimulating factor receptor activity 2/984 49/18639 0.0408163265306122 0.773145843703335 0.73880013845294 0.923629492917101 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/984 49/18639 0.0408163265306122 0.773145843703335 0.73880013845294 0.923629492917101 GO:0005020 stem cell factor receptor activity 2/984 49/18639 0.0408163265306122 0.773145843703335 0.73880013845294 0.923629492917101 GO:0008288 boss receptor activity 2/984 49/18639 0.0408163265306122 0.773145843703335 0.73880013845294 0.923629492917101 GO:0035254 glutamate receptor binding 2/984 49/18639 0.0408163265306122 0.773145843703335 0.73880013845294 0.923629492917101 GO:0036332 placental growth factor receptor activity 2/984 49/18639 0.0408163265306122 0.773145843703335 0.73880013845294 0.923629492917101 GO:0038062 protein tyrosine kinase collagen receptor activity 2/984 49/18639 0.0408163265306122 0.773145843703335 0.73880013845294 0.923629492917101 GO:0060175 brain-derived neurotrophic factor receptor activity 2/984 49/18639 0.0408163265306122 0.773145843703335 0.73880013845294 0.923629492917101 GO:0000030 mannosyltransferase activity 1/984 25/18639 0.04 0.757682926829268 0.742523322917937 0.923629492917101 GO:0003707 nuclear steroid receptor activity 1/984 25/18639 0.04 0.757682926829268 0.742523322917937 0.923629492917101 GO:0008483 transaminase activity 1/984 25/18639 0.04 0.757682926829268 0.742523322917937 0.923629492917101 GO:0015271 outward rectifier potassium channel activity 1/984 25/18639 0.04 0.757682926829268 0.742523322917937 0.923629492917101 GO:0015645 fatty acid ligase activity 1/984 25/18639 0.04 0.757682926829268 0.742523322917937 0.923629492917101 GO:0015662 P-type ion transporter activity 1/984 25/18639 0.04 0.757682926829268 0.742523322917937 0.923629492917101 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/984 25/18639 0.04 0.757682926829268 0.742523322917937 0.923629492917101 GO:0120020 cholesterol transfer activity 1/984 25/18639 0.04 0.757682926829268 0.742523322917937 0.923629492917101 GO:0120515 fatty acid-CoA ligase activity 1/984 25/18639 0.04 0.757682926829268 0.742523322917937 0.923629492917101 GO:0140358 P-type transmembrane transporter activity 1/984 25/18639 0.04 0.757682926829268 0.742523322917937 0.923629492917101 GO:0070851 growth factor receptor binding 6/984 139/18639 0.0431654676258993 0.817643446218635 0.748690603556048 0.923629492917101 GO:0005006 epidermal growth factor receptor activity 2/984 50/18639 0.04 0.757682926829268 0.748917344076965 0.923629492917101 GO:0005017 platelet-derived growth factor receptor activity 2/984 50/18639 0.04 0.757682926829268 0.748917344076965 0.923629492917101 GO:0005019 platelet-derived growth factor beta-receptor activity 2/984 50/18639 0.04 0.757682926829268 0.748917344076965 0.923629492917101 GO:0048020 CCR chemokine receptor binding 2/984 50/18639 0.04 0.757682926829268 0.748917344076965 0.923629492917101 GO:0003714 transcription corepressor activity 9/984 204/18639 0.0441176470588235 0.835679698708752 0.755442363582231 0.923629492917101 GO:0001637 G protein-coupled chemoattractant receptor activity 1/984 26/18639 0.0384615384615385 0.728541275797373 0.756134424790116 0.923629492917101 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/984 26/18639 0.0384615384615385 0.728541275797373 0.756134424790116 0.923629492917101 GO:0004435 phosphatidylinositol phospholipase C activity 1/984 26/18639 0.0384615384615385 0.728541275797373 0.756134424790116 0.923629492917101 GO:0004950 chemokine receptor activity 1/984 26/18639 0.0384615384615385 0.728541275797373 0.756134424790116 0.923629492917101 GO:0005160 transforming growth factor beta receptor binding 1/984 26/18639 0.0384615384615385 0.728541275797373 0.756134424790116 0.923629492917101 GO:0008143 poly(A) binding 1/984 26/18639 0.0384615384615385 0.728541275797373 0.756134424790116 0.923629492917101 GO:0008157 protein phosphatase 1 binding 1/984 26/18639 0.0384615384615385 0.728541275797373 0.756134424790116 0.923629492917101 GO:0015216 purine nucleotide transmembrane transporter activity 1/984 26/18639 0.0384615384615385 0.728541275797373 0.756134424790116 0.923629492917101 GO:0034237 protein kinase A regulatory subunit binding 1/984 26/18639 0.0384615384615385 0.728541275797373 0.756134424790116 0.923629492917101 GO:0043548 phosphatidylinositol 3-kinase binding 1/984 26/18639 0.0384615384615385 0.728541275797373 0.756134424790116 0.923629492917101 GO:0097602 cullin family protein binding 1/984 26/18639 0.0384615384615385 0.728541275797373 0.756134424790116 0.923629492917101 GO:0005010 insulin-like growth factor receptor activity 2/984 51/18639 0.0392156862745098 0.742826398852224 0.75869565489619 0.923629492917101 GO:0005021 vascular endothelial growth factor receptor activity 2/984 51/18639 0.0392156862745098 0.742826398852224 0.75869565489619 0.923629492917101 GO:0005030 neurotrophin receptor activity 2/984 51/18639 0.0392156862745098 0.742826398852224 0.75869565489619 0.923629492917101 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 2/984 52/18639 0.0384615384615385 0.728541275797373 0.768142614175775 0.927104941766248 GO:0030159 signaling receptor complex adaptor activity 2/984 52/18639 0.0384615384615385 0.728541275797373 0.768142614175775 0.927104941766248 GO:0016405 CoA-ligase activity 1/984 27/18639 0.037037037037037 0.701558265582656 0.769026689659107 0.927104941766248 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/984 27/18639 0.037037037037037 0.701558265582656 0.769026689659107 0.927104941766248 GO:0035255 ionotropic glutamate receptor binding 1/984 27/18639 0.037037037037037 0.701558265582656 0.769026689659107 0.927104941766248 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/984 27/18639 0.037037037037037 0.701558265582656 0.769026689659107 0.927104941766248 GO:0005003 ephrin receptor activity 2/984 53/18639 0.0377358490566038 0.714795213989876 0.777265913869836 0.927104941766248 GO:0005005 transmembrane-ephrin receptor activity 2/984 53/18639 0.0377358490566038 0.714795213989876 0.777265913869836 0.927104941766248 GO:0005544 calcium-dependent phospholipid binding 2/984 53/18639 0.0377358490566038 0.714795213989876 0.777265913869836 0.927104941766248 GO:0008146 sulfotransferase activity 2/984 53/18639 0.0377358490566038 0.714795213989876 0.777265913869836 0.927104941766248 GO:0017046 peptide hormone binding 2/984 53/18639 0.0377358490566038 0.714795213989876 0.777265913869836 0.927104941766248 GO:0038064 collagen receptor activity 2/984 53/18639 0.0377358490566038 0.714795213989876 0.777265913869836 0.927104941766248 GO:0051018 protein kinase A binding 2/984 53/18639 0.0377358490566038 0.714795213989876 0.777265913869836 0.927104941766248 GO:0004518 nuclease activity 9/984 209/18639 0.0430622009569378 0.815687361419069 0.77971211156596 0.927104941766248 GO:0016866 intramolecular transferase activity 1/984 28/18639 0.0357142857142857 0.676502613240418 0.781238044557852 0.927104941766248 GO:0045499 chemorepellent activity 1/984 28/18639 0.0357142857142857 0.676502613240418 0.781238044557852 0.927104941766248 GO:0046966 nuclear thyroid hormone receptor binding 1/984 28/18639 0.0357142857142857 0.676502613240418 0.781238044557852 0.927104941766248 GO:0050698 proteoglycan sulfotransferase activity 1/984 28/18639 0.0357142857142857 0.676502613240418 0.781238044557852 0.927104941766248 GO:0051019 mitogen-activated protein kinase binding 1/984 28/18639 0.0357142857142857 0.676502613240418 0.781238044557852 0.927104941766248 GO:0051393 alpha-actinin binding 1/984 28/18639 0.0357142857142857 0.676502613240418 0.781238044557852 0.927104941766248 GO:0051959 dynein light intermediate chain binding 1/984 28/18639 0.0357142857142857 0.676502613240418 0.781238044557852 0.927104941766248 GO:0141052 histone H3 demethylase activity 1/984 28/18639 0.0357142857142857 0.676502613240418 0.781238044557852 0.927104941766248 GO:0019199 transmembrane receptor protein kinase activity 3/984 78/18639 0.0384615384615385 0.728541275797373 0.787142239184229 0.933042745760711 GO:0035250 UDP-galactosyltransferase activity 1/984 29/18639 0.0344827586206897 0.653174936921783 0.79280441735647 0.937559739213523 GO:0099604 ligand-gated calcium channel activity 1/984 29/18639 0.0344827586206897 0.653174936921783 0.79280441735647 0.937559739213523 GO:0015370 solute:sodium symporter activity 3/984 79/18639 0.0379746835443038 0.719319234331584 0.794311235077448 0.937559739213523 GO:0008374 O-acyltransferase activity 2/984 55/18639 0.0363636363636364 0.68880266075388 0.794572829179028 0.937559739213523 GO:0005253 monoatomic anion channel activity 4/984 103/18639 0.0388349514563107 0.735614492067251 0.799572089100276 0.938776997013815 GO:0001965 G-protein alpha-subunit binding 1/984 30/18639 0.0333333333333333 0.63140243902439 0.80375984203789 0.938776997013815 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/984 30/18639 0.0333333333333333 0.63140243902439 0.80375984203789 0.938776997013815 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/984 30/18639 0.0333333333333333 0.63140243902439 0.80375984203789 0.938776997013815 GO:0015215 nucleotide transmembrane transporter activity 1/984 30/18639 0.0333333333333333 0.63140243902439 0.80375984203789 0.938776997013815 GO:0031624 ubiquitin conjugating enzyme binding 1/984 30/18639 0.0333333333333333 0.63140243902439 0.80375984203789 0.938776997013815 GO:0032452 histone demethylase activity 1/984 30/18639 0.0333333333333333 0.63140243902439 0.80375984203789 0.938776997013815 GO:0051721 protein phosphatase 2A binding 1/984 30/18639 0.0333333333333333 0.63140243902439 0.80375984203789 0.938776997013815 GO:0070566 adenylyltransferase activity 1/984 30/18639 0.0333333333333333 0.63140243902439 0.80375984203789 0.938776997013815 GO:0004519 endonuclease activity 5/984 127/18639 0.0393700787401575 0.745750912233532 0.806790151554003 0.941255176813003 GO:0005184 neuropeptide hormone activity 1/984 31/18639 0.032258064516129 0.6110346184107 0.814136558435048 0.944507810233718 GO:0016411 acylglycerol O-acyltransferase activity 1/984 31/18639 0.032258064516129 0.6110346184107 0.814136558435048 0.944507810233718 GO:0016878 acid-thiol ligase activity 1/984 31/18639 0.032258064516129 0.6110346184107 0.814136558435048 0.944507810233718 GO:0017147 Wnt-protein binding 1/984 31/18639 0.032258064516129 0.6110346184107 0.814136558435048 0.944507810233718 GO:0140457 protein demethylase activity 1/984 31/18639 0.032258064516129 0.6110346184107 0.814136558435048 0.944507810233718 GO:0004497 monooxygenase activity 4/984 106/18639 0.0377358490566038 0.714795213989876 0.817317391951118 0.947137380381832 GO:0030165 PDZ domain binding 3/984 83/18639 0.036144578313253 0.684653247134881 0.820997109993385 0.949359811643589 GO:0008378 galactosyltransferase activity 1/984 32/18639 0.03125 0.591939786585366 0.823965106720727 0.949359811643589 GO:0070717 poly-purine tract binding 1/984 32/18639 0.03125 0.591939786585366 0.823965106720727 0.949359811643589 GO:0120015 sterol transfer activity 1/984 32/18639 0.03125 0.591939786585366 0.823965106720727 0.949359811643589 GO:0160041 neuropeptide activity 1/984 32/18639 0.03125 0.591939786585366 0.823965106720727 0.949359811643589 GO:0031593 polyubiquitin modification-dependent protein binding 2/984 59/18639 0.0338983050847458 0.642104175279041 0.825649797578064 0.949359811643589 GO:0070888 E-box binding 2/984 59/18639 0.0338983050847458 0.642104175279041 0.825649797578064 0.949359811643589 GO:0004843 cysteine-type deubiquitinase activity 4/984 108/18639 0.037037037037037 0.701558265582656 0.828414907436682 0.951483197454992 GO:0030296 protein tyrosine kinase activator activity 1/984 33/18639 0.0303030303030303 0.5740022172949 0.833274416925854 0.956004757403306 GO:0008175 tRNA methyltransferase activity 1/984 34/18639 0.0294117647058824 0.557119799139168 0.842091893747576 0.961860200576063 GO:0015020 glucuronosyltransferase activity 1/984 34/18639 0.0294117647058824 0.557119799139168 0.842091893747576 0.961860200576063 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/984 34/18639 0.0294117647058824 0.557119799139168 0.842091893747576 0.961860200576063 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/984 34/18639 0.0294117647058824 0.557119799139168 0.842091893747576 0.961860200576063 GO:1902936 phosphatidylinositol bisphosphate binding 4/984 111/18639 0.036036036036036 0.682597231377719 0.844006203720686 0.96298505182228 GO:0008168 methyltransferase activity 8/984 204/18639 0.0392156862745098 0.742826398852224 0.849846538959098 0.968581973995187 GO:0000993 RNA polymerase II complex binding 1/984 36/18639 0.0277777777777778 0.526168699186992 0.858353817205158 0.97292620856077 GO:0004033 aldo-keto reductase (NADPH) activity 1/984 36/18639 0.0277777777777778 0.526168699186992 0.858353817205158 0.97292620856077 GO:0004190 aspartic-type endopeptidase activity 1/984 36/18639 0.0277777777777778 0.526168699186992 0.858353817205158 0.97292620856077 GO:0005484 SNAP receptor activity 1/984 36/18639 0.0277777777777778 0.526168699186992 0.858353817205158 0.97292620856077 GO:0045505 dynein intermediate chain binding 1/984 36/18639 0.0277777777777778 0.526168699186992 0.858353817205158 0.97292620856077 GO:1901981 phosphatidylinositol phosphate binding 7/984 185/18639 0.0378378378378378 0.716727092946605 0.86270909424311 0.976079009916078 GO:0120013 lipid transfer activity 2/984 65/18639 0.0307692307692308 0.582833020637899 0.864367568155522 0.976079009916078 GO:0001664 G protein-coupled receptor binding 12/984 297/18639 0.0404040404040404 0.765336289726534 0.865198986870174 0.976079009916078 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 3/984 91/18639 0.032967032967033 0.624463950683463 0.865586149246434 0.976079009916078 GO:0070001 aspartic-type peptidase activity 1/984 37/18639 0.027027027027027 0.511947923533289 0.865846148757602 0.976079009916078 GO:0008235 metalloexopeptidase activity 2/984 66/18639 0.0303030303030303 0.5740022172949 0.869997339931327 0.979692656705277 GO:0015103 inorganic anion transmembrane transporter activity 6/984 165/18639 0.0363636363636364 0.68880266075388 0.87354793055691 0.98262286216825 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/984 39/18639 0.0256410256410256 0.485694183864916 0.879663944410582 0.988428237383887 GO:1990841 promoter-specific chromatin binding 2/984 68/18639 0.0294117647058824 0.557119799139168 0.880617049329467 0.988428237383887 GO:0019955 cytokine binding 5/984 144/18639 0.0347222222222222 0.65771087398374 0.882856290802035 0.989145683070735 GO:0016279 protein-lysine N-methyltransferase activity 2/984 69/18639 0.0289855072463768 0.549045599151644 0.88562094030496 0.989145683070735 GO:0016741 transferase activity, transferring one-carbon groups 8/984 215/18639 0.0372093023255814 0.70482132728304 0.886028372396365 0.989145683070735 GO:0032451 demethylase activity 1/984 40/18639 0.025 0.473551829268293 0.886030109932087 0.989145683070735 GO:0071949 FAD binding 1/984 40/18639 0.025 0.473551829268293 0.886030109932087 0.989145683070735 GO:0016278 lysine N-methyltransferase activity 2/984 70/18639 0.0285714285714286 0.541202090592334 0.890429915865566 0.989479616767292 GO:0016782 transferase activity, transferring sulphur-containing groups 2/984 70/18639 0.0285714285714286 0.541202090592334 0.890429915865566 0.989479616767292 GO:0004812 aminoacyl-tRNA ligase activity 1/984 41/18639 0.024390243902439 0.462001784651993 0.892059808938852 0.989479616767292 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/984 41/18639 0.024390243902439 0.462001784651993 0.892059808938852 0.989479616767292 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/984 41/18639 0.024390243902439 0.462001784651993 0.892059808938852 0.989479616767292 GO:0042169 SH2 domain binding 1/984 41/18639 0.024390243902439 0.462001784651993 0.892059808938852 0.989479616767292 GO:0015085 calcium ion transmembrane transporter activity 5/984 147/18639 0.0340136054421769 0.644288203086112 0.89321679816725 0.989703318610984 GO:0008170 N-methyltransferase activity 3/984 98/18639 0.0306122448979592 0.579859382777501 0.896264023512535 0.990504322485473 GO:0004402 histone acetyltransferase activity 1/984 42/18639 0.0238095238095238 0.451001742160279 0.897770807326 0.990504322485473 GO:0043175 RNA polymerase core enzyme binding 1/984 42/18639 0.0238095238095238 0.451001742160279 0.897770807326 0.990504322485473 GO:0005518 collagen binding 2/984 72/18639 0.0277777777777778 0.526168699186992 0.899489398592669 0.990504322485473 GO:0042379 chemokine receptor binding 2/984 72/18639 0.0277777777777778 0.526168699186992 0.899489398592669 0.990504322485473 GO:0008509 monoatomic anion transmembrane transporter activity 5/984 149/18639 0.0335570469798658 0.635640039286299 0.899676223415859 0.990504322485473 GO:0035064 methylated histone binding 2/984 74/18639 0.027027027027027 0.511947923533289 0.907846504311049 0.998438406015124 GO:0008238 exopeptidase activity 3/984 102/18639 0.0294117647058824 0.557119799139168 0.910822401493344 0.999997074367171 GO:0008009 chemokine activity 1/984 45/18639 0.0222222222222222 0.420934959349593 0.913155494064868 0.999997074367171 GO:0042605 peptide antigen binding 1/984 45/18639 0.0222222222222222 0.420934959349593 0.913155494064868 0.999997074367171 GO:0035591 signaling adaptor activity 4/984 129/18639 0.0310077519379845 0.5873511060692 0.914415786859142 0.999997074367171 GO:0140034 methylation-dependent protein binding 2/984 76/18639 0.0263157894736842 0.498475609756098 0.915549726392228 0.999997074367171 GO:0016798 hydrolase activity, acting on glycosyl bonds 4/984 130/18639 0.0307692307692308 0.582833020637899 0.917332037855715 0.999997074367171 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/984 46/18639 0.0217391304347826 0.411784199363733 0.91775133110048 0.999997074367171 GO:0140098 catalytic activity, acting on RNA 15/984 387/18639 0.0387596899224806 0.7341888825865 0.91880077170521 0.999997074367171 GO:0003724 RNA helicase activity 2/984 77/18639 0.025974025974026 0.492001900538486 0.919170591719959 0.999997074367171 GO:0005543 phospholipid binding 20/984 497/18639 0.0402414486921529 0.762256465623006 0.91926858430124 0.999997074367171 GO:0004674 protein serine/threonine kinase activity 17/984 433/18639 0.0392609699769053 0.743684166056441 0.921773612426644 0.999997074367171 GO:0005085 guanyl-nucleotide exchange factor activity 8/984 230/18639 0.0347826086956522 0.658854718981972 0.923424720788145 0.999997074367171 GO:0008186 ATP-dependent activity, acting on RNA 2/984 79/18639 0.0253164556962025 0.479546156221056 0.925978367166013 0.999997074367171 GO:0008188 neuropeptide receptor activity 1/984 48/18639 0.0208333333333333 0.394626524390244 0.926226902055188 0.999997074367171 GO:0015605 organophosphate ester transmembrane transporter activity 1/984 50/18639 0.02 0.378841463414634 0.933829876954451 0.999997074367171 GO:0031267 small GTPase binding 10/984 283/18639 0.0353356890459364 0.66933120744635 0.934865788722502 0.999997074367171 GO:0035091 phosphatidylinositol binding 10/984 284/18639 0.0352112676056338 0.666974407420131 0.936519976593854 0.999997074367171 GO:0016597 amino acid binding 1/984 51/18639 0.0196078431372549 0.371413199426112 0.937332561395616 0.999997074367171 GO:0005254 chloride channel activity 2/984 83/18639 0.0240963855421687 0.456435498089921 0.93800246416318 0.999997074367171 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 5/984 167/18639 0.029940119760479 0.567127939243464 0.94403992004185 0.999997074367171 GO:0016874 ligase activity 5/984 167/18639 0.029940119760479 0.567127939243464 0.94403992004185 0.999997074367171 GO:0050660 flavin adenine dinucleotide binding 2/984 86/18639 0.0232558139534884 0.4405133295519 0.945778453772497 0.999997074367171 GO:0035173 histone kinase activity 13/984 360/18639 0.0361111111111111 0.684019308943089 0.946044181596011 0.999997074367171 GO:0140463 chromatin-protein adaptor activity 1/984 54/18639 0.0185185185185185 0.350779132791328 0.946767836899824 0.999997074367171 GO:0106310 protein serine kinase activity 13/984 361/18639 0.03601108033241 0.682124518613607 0.947318899261144 0.999997074367171 GO:0008194 UDP-glycosyltransferase activity 4/984 145/18639 0.0275862068965517 0.522539949537426 0.951563177160058 0.999997074367171 GO:0035402 histone H3T11 kinase activity 8/984 247/18639 0.0323886639676113 0.613508442776736 0.952537623492453 0.999997074367171 GO:0015108 chloride transmembrane transporter activity 3/984 121/18639 0.0247933884297521 0.469638177786737 0.957684298222302 0.999997074367171 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/984 122/18639 0.0245901639344262 0.46578868452619 0.959357525630556 0.999997074367171 GO:0030695 GTPase regulator activity 18/984 489/18639 0.0368098159509202 0.697254227143498 0.961719366783198 0.999997074367171 GO:0060589 nucleoside-triphosphatase regulator activity 18/984 490/18639 0.036734693877551 0.695831259333002 0.962556406048745 0.999997074367171 GO:0141003 histone H2AX kinase activity 12/984 354/18639 0.0338983050847458 0.642104175279041 0.964928772146601 0.999997074367171 GO:0005125 cytokine activity 7/984 234/18639 0.0299145299145299 0.566643214509068 0.966773696016357 0.999997074367171 GO:0140996 histone H3 kinase activity 12/984 357/18639 0.0336134453781513 0.636708341873335 0.967561355044207 0.999997074367171 GO:0030527 structural constituent of chromatin 2/984 98/18639 0.0204081632653061 0.386572921851667 0.968535692082869 0.999997074367171 GO:0005262 calcium channel activity 3/984 131/18639 0.0229007633587786 0.433787935207596 0.971855890814621 0.999997074367171 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 8/984 268/18639 0.0298507462686567 0.565435020021842 0.974651673899003 0.999997074367171 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 7/984 243/18639 0.0288065843621399 0.54565642878651 0.975039953523813 0.999997074367171 GO:0015081 sodium ion transmembrane transporter activity 4/984 164/18639 0.024390243902439 0.462001784651993 0.976224024518971 0.999997074367171 GO:0004676 3-phosphoinositide-dependent protein kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:0004711 ribosomal protein S6 kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:0035175 histone H3S10 kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:0035979 histone H2AXS139 kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:0044022 histone H3S28 kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:0044023 histone H4S1 kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:0044024 histone H2AS1 kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:0044025 histone H2BS14 kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:0072354 histone H3T3 kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:0072371 histone H2AS121 kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:0072518 Rho-dependent protein serine/threonine kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:0140823 histone H2BS36 kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:0140855 histone H3S57 kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:0140995 histone H2A kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:0140997 histone H4 kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:0140998 histone H2B kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:1990244 histone H2AT120 kinase activity 7/984 245/18639 0.0285714285714286 0.541202090592334 0.976599140571777 0.999997074367171 GO:0005096 GTPase activator activity 8/984 271/18639 0.029520295202952 0.559175591755917 0.976894005190289 0.999997074367171 GO:0004677 DNA-dependent protein kinase activity 7/984 246/18639 0.0284552845528455 0.539002082093992 0.977344629927784 0.999997074367171 GO:0140857 histone H3T45 kinase activity 7/984 246/18639 0.0284552845528455 0.539002082093992 0.977344629927784 0.999997074367171 GO:0035403 histone H3T6 kinase activity 7/984 247/18639 0.0283400809716599 0.536819887429644 0.978068167615481 0.999997074367171 GO:0008013 beta-catenin binding 2/984 106/18639 0.0188679245283019 0.357397606994938 0.978248479685661 0.999997074367171 GO:0004679 AMP-activated protein kinase activity 7/984 248/18639 0.0282258064516129 0.534655291109363 0.978770326812723 0.999997074367171 GO:0140101 catalytic activity, acting on a tRNA 3/984 139/18639 0.0215827338129496 0.408821723109317 0.979822624194179 0.999997074367171 GO:0140767 enzyme-substrate adaptor activity 3/984 139/18639 0.0215827338129496 0.408821723109317 0.979822624194179 0.999997074367171 GO:0001217 DNA-binding transcription repressor activity 8/984 278/18639 0.0287769784172662 0.545095630812423 0.981436113384443 0.999997074367171 GO:0140030 modification-dependent protein binding 4/984 173/18639 0.023121387283237 0.437967009727901 0.983222269109595 0.999997074367171 GO:0008528 G protein-coupled peptide receptor activity 2/984 122/18639 0.0163934426229508 0.310525789684126 0.989735065781596 0.999997074367171 GO:0001653 peptide receptor activity 2/984 128/18639 0.015625 0.295969893292683 0.992283356321362 0.999997074367171 GO:0005201 extracellular matrix structural constituent 3/984 168/18639 0.0178571428571429 0.338251306620209 0.994200774029884 0.999997074367171 GO:0004896 cytokine receptor activity 1/984 96/18639 0.0104166666666667 0.197313262195122 0.994595092994246 0.999997074367171 GO:0005249 voltage-gated potassium channel activity 1/984 98/18639 0.0102040816326531 0.193286460925834 0.995153519445487 0.999997074367171 GO:0005244 voltage-gated monoatomic ion channel activity 3/984 173/18639 0.0173410404624277 0.328475257295926 0.995348258320403 0.999997074367171 GO:0022832 voltage-gated channel activity 3/984 175/18639 0.0171428571428571 0.324721254355401 0.995742644579695 0.999997074367171 GO:0046873 metal ion transmembrane transporter activity 12/984 450/18639 0.0266666666666667 0.505121951219512 0.997836058368749 0.999997074367171 GO:0140375 immune receptor activity 2/984 156/18639 0.0128205128205128 0.242847091932458 0.998006505555276 0.999997074367171 GO:0005267 potassium channel activity 1/984 124/18639 0.00806451612903226 0.152758654602675 0.99882714195674 0.999997074367171 GO:0016755 aminoacyltransferase activity 13/984 496/18639 0.0262096774193548 0.496465627458694 0.998842887556491 0.999997074367171 GO:0019787 ubiquitin-like protein transferase activity 12/984 479/18639 0.0250521920668058 0.474540455216661 0.999156040572236 0.999997074367171 GO:0003823 antigen binding 2/984 174/18639 0.0114942528735632 0.217724978973928 0.999177843449587 0.999997074367171 GO:0099094 ligand-gated monoatomic cation channel activity 1/984 136/18639 0.00735294117647059 0.139279949784792 0.9993910884679 0.999997074367171 GO:0022843 voltage-gated monoatomic cation channel activity 1/984 143/18639 0.00699300699300699 0.132462050144977 0.999584666794486 0.999997074367171 GO:0004842 ubiquitin-protein transferase activity 10/984 449/18639 0.022271714922049 0.421872453691129 0.99964849220454 0.999997074367171 GO:0015079 potassium ion transmembrane transporter activity 1/984 160/18639 0.00625 0.118387957317073 0.999836091320653 0.999997074367171 GO:0022836 gated channel activity 5/984 318/18639 0.0157232704402516 0.297831339162448 0.999848510283324 0.999997074367171 GO:0005216 monoatomic ion channel activity 9/984 448/18639 0.0200892857142857 0.380532719947735 0.999875705279732 0.999997074367171 GO:0045182 translation regulator activity 6/984 356/18639 0.0168539325842697 0.319248424225815 0.999878602565658 0.999997074367171 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 10/984 484/18639 0.0206611570247934 0.391365148155614 0.999902682795122 0.999997074367171 GO:0001216 DNA-binding transcription activator activity 10/984 491/18639 0.0203665987780041 0.385785604291888 0.999925157453454 0.999997074367171 GO:0061659 ubiquitin-like protein ligase activity 6/984 372/18639 0.0161290322580645 0.30551730920535 0.999938041412938 0.999997074367171 GO:0015276 ligand-gated monoatomic ion channel activity 1/984 186/18639 0.00537634408602151 0.10183910306845 0.999960527516351 0.999997074367171 GO:0022834 ligand-gated channel activity 1/984 188/18639 0.00531914893617021 0.100755708354956 0.999964625097307 0.999997074367171 GO:0061630 ubiquitin protein ligase activity 5/984 353/18639 0.0141643059490085 0.268301319698749 0.999967244636124 0.999997074367171 GO:0005261 monoatomic cation channel activity 4/984 341/18639 0.0117302052785924 0.2221944066948 0.999989048699462 0.999997074367171 GO:0030371 translation repressor activity 3/984 329/18639 0.00911854103343465 0.172724071465639 0.999997074367171 0.999997074367171