ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0045296	cadherin binding	35/458	334/18639	0.104790419161677	4.2646039798133	4.99680048887505e-13	3.75759396763404e-10
GO:0031720	haptoglobin binding	8/458	10/18639	0.8	32.5572052401747	5.3933908869115e-12	2.02791497347872e-09
GO:0051082	unfolded protein binding	19/458	121/18639	0.15702479338843	6.39036053267891	1.24529097538694e-10	3.12152937830326e-08
GO:0005344	oxygen carrier activity	8/458	14/18639	0.571428571428571	23.2551466001248	3.30014005395978e-10	6.2042633014444e-08
GO:0140662	ATP-dependent protein folding chaperone	11/458	40/18639	0.275	11.19153930131	2.12748070331811e-09	3.19973097779043e-07
GO:0044183	protein folding chaperone	14/458	75/18639	0.186666666666667	7.59668122270742	3.42615781092617e-09	4.29411778969413e-07
GO:0019825	oxygen binding	9/458	34/18639	0.264705882352941	10.7726046750578	9.17610160159176e-08	9.8577548634243e-06
GO:0004601	peroxidase activity	11/458	57/18639	0.192982456140351	7.85371179039301	1.16531053255167e-07	1.09539190059857e-05
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	11/458	59/18639	0.186440677966102	7.58748427207461	1.69111159347053e-07	1.34102615865481e-05
GO:0005201	extracellular matrix structural constituent	18/458	168/18639	0.107142857142857	4.36033998752339	1.78327946629629e-07	1.34102615865481e-05
GO:0140104	molecular carrier activity	21/458	249/18639	0.0843373493975904	3.43223549218709	9.87506271565722e-07	6.24935563091309e-05
GO:0030020	extracellular matrix structural constituent conferring tensile strength	9/458	44/18639	0.204545454545455	8.32428543072648	9.97237600677622e-07	6.24935563091309e-05
GO:0044389	ubiquitin-like protein ligase binding	24/458	322/18639	0.0745341614906832	3.03327999132062	1.55700835477629e-06	9.00669448301363e-05
GO:0005200	structural constituent of cytoskeleton	13/458	112/18639	0.116071428571429	4.72370165315034	3.7433166658181e-06	0.000201069580906801
GO:0051015	actin filament binding	18/458	209/18639	0.0861244019138756	3.50496228662168	4.36389684065089e-06	0.000218776694944631
GO:0004857	enzyme inhibitor activity	27/458	416/18639	0.0649038461538462	2.64135980013436	4.87967775693186e-06	0.000229344854575797
GO:0031625	ubiquitin protein ligase binding	22/458	302/18639	0.0728476821192053	2.96464617253246	6.12561068674783e-06	0.000270968190378492
GO:0003735	structural constituent of ribosome	16/458	175/18639	0.0914285714285714	3.72082345601996	6.93142749726811e-06	0.000289579637663645
GO:0016209	antioxidant activity	11/458	86/18639	0.127906976744186	5.20536711688839	8.14586430711259e-06	0.000322404734681509
GO:0003725	double-stranded RNA binding	10/458	75/18639	0.133333333333333	5.42620087336245	1.44569322516125e-05	0.000523091144735708
GO:0044548	S100 protein binding	5/458	14/18639	0.357142857142857	14.534466625078	1.46075984567153e-05	0.000523091144735708
GO:0019887	protein kinase regulator activity	19/458	255/18639	0.0745098039215686	3.0322887233496	1.91375161179497e-05	0.000654155096395372
GO:0016860	intramolecular oxidoreductase activity	8/458	53/18639	0.150943396226415	6.1428689132405	4.19963946844704e-05	0.00137309951316181
GO:0097718	disordered domain specific binding	6/458	28/18639	0.214285714285714	8.72067997504679	5.06850553864291e-05	0.00158813173544145
GO:0003756	protein disulfide isomerase activity	5/458	19/18639	0.263157894736842	10.7096069868996	7.66394902594981e-05	0.00205831773839795
GO:0005520	insulin-like growth factor binding	5/458	19/18639	0.263157894736842	10.7096069868996	7.66394902594981e-05	0.00205831773839795
GO:0008301	DNA binding, bending	5/458	19/18639	0.263157894736842	10.7096069868996	7.66394902594981e-05	0.00205831773839795
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	5/458	19/18639	0.263157894736842	10.7096069868996	7.66394902594981e-05	0.00205831773839795
GO:0019207	kinase regulator activity	19/458	287/18639	0.0662020905923345	2.69419381342909	9.5224584208911e-05	0.00246927197672762
GO:0048407	platelet-derived growth factor binding	4/458	11/18639	0.363636363636364	14.7987296546249	0.000103520885790854	0.00259492353715741
GO:0016887	ATP hydrolysis activity	24/458	417/18639	0.0575539568345324	2.34224498130753	0.000110165393800092	0.00263624879080435
GO:0140142	nucleocytoplasmic carrier activity	6/458	32/18639	0.1875	7.63059497816594	0.000112180799608696	0.00263624879080435
GO:0019838	growth factor binding	12/458	136/18639	0.0882352941176471	3.59086822501927	0.000135841844777509	0.00309554749311172
GO:0015035	protein-disulfide reductase activity	6/458	34/18639	0.176470588235294	7.18173645003853	0.000159714419110269	0.00350894141732927
GO:0140517	protein-RNA adaptor activity	5/458	22/18639	0.227272727272727	9.24920603414053	0.000163315092561868	0.00350894141732927
GO:0005178	integrin binding	13/458	161/18639	0.0807453416149068	3.28605332393067	0.000177178226123328	0.00370105627902062
GO:0020037	heme binding	12/458	142/18639	0.0845070422535211	3.43914139861	0.000204206990560968	0.00415036910545535
GO:0031994	insulin-like growth factor I binding	4/458	13/18639	0.307692307692308	12.5220020154518	0.000215688505927585	0.00426836201204063
GO:0005540	hyaluronic acid binding	5/458	24/18639	0.208333333333333	8.47843886462882	0.000253128017227061	0.00475880672386875
GO:0048027	mRNA 5'-UTR binding	5/458	24/18639	0.208333333333333	8.47843886462882	0.000253128017227061	0.00475880672386875
GO:0003779	actin binding	24/458	443/18639	0.054176072234763	2.20477687856713	0.00027219656425376	0.00499248332484944
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	7/458	54/18639	0.12962962962963	5.2754730713246	0.000337331566247498	0.00603984137662186
GO:0046906	tetrapyrrole binding	12/458	152/18639	0.0789473684210526	3.21288209606987	0.000383024965103573	0.00669848311064853
GO:0015036	disulfide oxidoreductase activity	6/458	40/18639	0.15	6.10447598253275	0.000402498354100874	0.00687906277917858
GO:0005159	insulin-like growth factor receptor binding	4/458	16/18639	0.25	10.1741266375546	0.000517792166804299	0.00856627643044904
GO:0016853	isomerase activity	13/458	180/18639	0.0722222222222222	2.93919213973799	0.000524000951862574	0.00856627643044904
GO:0036002	pre-mRNA binding	7/458	59/18639	0.11864406779661	4.82839908222929	0.000584866813071606	0.00935786900914569
GO:0003697	single-stranded DNA binding	10/458	121/18639	0.0826446280991736	3.36334764877838	0.000810405239796611	0.0126963487568136
GO:0019843	rRNA binding	7/458	65/18639	0.107692307692308	4.38270070540813	0.00105217105764601	0.0160217722318378
GO:0051117	ATPase binding	8/458	84/18639	0.0952380952380952	3.87585776668746	0.00106527740903177	0.0160217722318378
GO:0072542	protein phosphatase activator activity	4/458	21/18639	0.19047619047619	7.75171553337492	0.00154488545496369	0.0227794874927979
GO:0051087	protein-folding chaperone binding	10/458	134/18639	0.0746268656716418	3.03705272762823	0.00176294569964787	0.0254949070410615
GO:0030021	extracellular matrix structural constituent conferring compression resistance	4/458	22/18639	0.181818181818182	7.39936482731243	0.00185190109105298	0.0262760305749404
GO:0005518	collagen binding	7/458	72/18639	0.0972222222222222	3.95660480349345	0.00192254809165053	0.0267732623133555
GO:0044325	transmembrane transporter binding	10/458	136/18639	0.0735294117647059	2.99239018751605	0.00196821175916376	0.0269108225980209
GO:0009055	electron transfer activity	9/458	116/18639	0.0775862068965517	3.15748757717211	0.0022637518967552	0.0303989540421413
GO:0019208	phosphatase regulator activity	9/458	117/18639	0.0769230769230769	3.13050050386295	0.00240047589943567	0.0316694364276425
GO:0015399	primary active transmembrane transporter activity	11/458	166/18639	0.0662650602409639	2.696756458147	0.0027250525676056	0.0344473410565344
GO:0005049	nuclear export signal receptor activity	3/458	12/18639	0.25	10.1741266375546	0.00274845806302136	0.0344473410565344
GO:1990247	N6-methyladenosine-containing RNA reader activity	3/458	12/18639	0.25	10.1741266375546	0.00274845806302136	0.0344473410565344
GO:0019211	phosphatase activator activity	4/458	25/18639	0.16	6.51144104803493	0.00302170454281435	0.037251177314695
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	5/458	41/18639	0.121951219512195	4.96298860368516	0.00316891179508755	0.0384358333855781
GO:0043560	insulin receptor substrate binding	3/458	13/18639	0.230769230769231	9.39150151158885	0.0035082889301495	0.0418767186582924
GO:0048156	tau protein binding	5/458	43/18639	0.116279069767442	4.73215192444399	0.00391069322427463	0.0459506453852269
GO:0023026	MHC class II protein complex binding	4/458	27/18639	0.148148148148148	6.02911208151383	0.00403318021734026	0.0466607926683058
GO:0004860	protein kinase inhibitor activity	7/458	84/18639	0.0833333333333333	3.39137554585153	0.00460126553350812	0.0524265406242138
GO:0022804	active transmembrane transporter activity	21/458	457/18639	0.0459518599562363	1.87008016970369	0.00471292348627863	0.0528972904728587
GO:0005506	iron ion binding	10/458	154/18639	0.0649350649350649	2.64263029546872	0.00482003983908485	0.0533039699851736
GO:0051020	GTPase binding	16/458	315/18639	0.0507936507936508	2.06712414223331	0.00511922928504017	0.055792180034061
GO:0004129	cytochrome-c oxidase activity	3/458	15/18639	0.2	8.13930131004367	0.00538141995284907	0.0578118257791786
GO:0008187	poly-pyrimidine tract binding	4/458	30/18639	0.133333333333333	5.42620087336245	0.00594388054318342	0.062954903781323
GO:0003727	single-stranded RNA binding	7/458	89/18639	0.0786516853932584	3.20084882979245	0.00630820797944043	0.0658857277852667
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	6/458	68/18639	0.0882352941176471	3.59086822501927	0.00645300584298676	0.0660926255138976
GO:0016675	oxidoreductase activity, acting on a heme group of donors	3/458	16/18639	0.1875	7.63059497816594	0.00650379559578247	0.0660926255138976
GO:0019210	kinase inhibitor activity	7/458	90/18639	0.0777777777777778	3.16528384279476	0.0066995912402346	0.0671745681687523
GO:0005539	glycosaminoglycan binding	13/458	242/18639	0.0537190082644628	2.18617597170594	0.00707408420033195	0.0699962015611793
GO:0015631	tubulin binding	18/458	385/18639	0.0467532467532468	1.90269381273748	0.00719773182632693	0.0702947316025695
GO:0030515	snoRNA binding	4/458	32/18639	0.125	5.08706331877729	0.00750488974504124	0.072354834465013
GO:0051787	misfolded protein binding	3/458	17/18639	0.176470588235294	7.18173645003853	0.00775517112563047	0.0728986085809264
GO:1990226	histone methyltransferase binding	3/458	17/18639	0.176470588235294	7.18173645003853	0.00775517112563047	0.0728986085809264
GO:0005048	signal sequence binding	5/458	51/18639	0.0980392156862745	3.98985358335474	0.00813545172972185	0.075529132108035
GO:0022853	active monoatomic ion transmembrane transporter activity	8/458	118/18639	0.0677966101694915	2.75908518984531	0.00871288660714304	0.0799035454703849
GO:0042277	peptide binding	13/458	249/18639	0.0522088353413655	2.12471720944915	0.00888009443906447	0.0804557953997167
GO:0043539	protein serine/threonine kinase activator activity	6/458	73/18639	0.0821917808219178	3.34491834659329	0.0090635021142919	0.0811399236898513
GO:0055106	ubiquitin-protein transferase regulator activity	4/458	36/18639	0.111111111111111	4.52183406113537	0.0113851198725564	0.10072482522544
GO:0004252	serine-type endopeptidase activity	10/458	176/18639	0.0568181818181818	2.31230150853513	0.0118777466530597	0.103537406727832
GO:0019212	phosphatase inhibitor activity	5/458	56/18639	0.0892857142857143	3.63361665626949	0.0119783967889913	0.103537406727832
GO:0061608	nuclear import signal receptor activity	3/458	20/18639	0.15	6.10447598253275	0.0123128925746694	0.104122048313205
GO:0043021	ribonucleoprotein complex binding	10/458	177/18639	0.0564971751412429	2.29923765820443	0.0123229551860043	0.104122048313205
GO:0023023	MHC protein complex binding	4/458	37/18639	0.108108108108108	4.39962232975333	0.0125230460030958	0.104637006603645
GO:0046332	SMAD binding	6/458	79/18639	0.0759493670886076	3.09087391520646	0.0131002182325235	0.107704010260049
GO:0003730	mRNA 3'-UTR binding	13/458	262/18639	0.049618320610687	2.01929230974366	0.0131765544467081	0.107704010260049
GO:0061980	regulatory RNA binding	5/458	58/18639	0.0862068965517241	3.50831953019124	0.0138106023231216	0.111672827386962
GO:0070182	DNA polymerase binding	3/458	21/18639	0.142857142857143	5.81378665003119	0.0141075604279537	0.11286048342363
GO:0000217	DNA secondary structure binding	4/458	39/18639	0.102564102564103	4.17400067181727	0.0150108014678572	0.118822344250827
GO:0070034	telomerase RNA binding	3/458	22/18639	0.136363636363636	5.54952362048432	0.0160426645337802	0.125667538847945
GO:0005179	hormone activity	8/458	132/18639	0.0606060606060606	2.46645494243748	0.0163574068005679	0.126220863999093
GO:0019888	protein phosphatase regulator activity	7/458	107/18639	0.0654205607476635	2.66238827898625	0.0164489955743499	0.126220863999093
GO:0001530	lipopolysaccharide binding	4/458	41/18639	0.0975609756097561	3.97039088294813	0.0177896629685754	0.133778265523687
GO:0015175	neutral L-amino acid transmembrane transporter activity	4/458	41/18639	0.0975609756097561	3.97039088294813	0.0177896629685754	0.133778265523687
GO:0099186	structural constituent of postsynapse	3/458	23/18639	0.130434782608696	5.30823998481109	0.0181192556519529	0.134907725250184
GO:0019894	kinesin binding	4/458	42/18639	0.0952380952380952	3.87585776668746	0.0192911198840998	0.139489636085029
GO:0035198	miRNA binding	4/458	42/18639	0.0952380952380952	3.87585776668746	0.0192911198840998	0.139489636085029
GO:0042056	chemoattractant activity	4/458	42/18639	0.0952380952380952	3.87585776668746	0.0192911198840998	0.139489636085029
GO:0001091	RNA polymerase II general transcription initiation factor binding	3/458	24/18639	0.125	5.08706331877729	0.0203380289034163	0.144284884295934
GO:0070840	dynein complex binding	3/458	24/18639	0.125	5.08706331877729	0.0203380289034163	0.144284884295934
GO:0003712	transcription coregulator activity	20/458	495/18639	0.0404040404040404	1.64430329495832	0.0210193135473852	0.147724521379754
GO:0030295	protein kinase activator activity	8/458	139/18639	0.0575539568345324	2.34224498130753	0.0216093407823776	0.15046503952174
GO:0008236	serine-type peptidase activity	10/458	194/18639	0.0515463917525773	2.09775806959888	0.0219661196920743	0.151546073471925
GO:0042974	nuclear retinoic acid receptor binding	3/458	25/18639	0.12	4.8835807860262	0.0226993458616802	0.155180982618032
GO:0001094	TFIID-class transcription factor complex binding	2/458	10/18639	0.2	8.13930131004367	0.0237927844635022	0.158337822270387
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/458	10/18639	0.2	8.13930131004367	0.0237927844635022	0.158337822270387
GO:0030957	Tat protein binding	2/458	10/18639	0.2	8.13930131004367	0.0237927844635022	0.158337822270387
GO:0061134	peptidase regulator activity	11/458	226/18639	0.0486725663716814	1.98080341616107	0.0244057019005598	0.160991998501938
GO:0017171	serine hydrolase activity	10/458	198/18639	0.0505050505050505	2.0553791186979	0.0248661189647527	0.16260279531734
GO:0000287	magnesium ion binding	11/458	230/18639	0.0478260869565217	1.9463546610974	0.027294687801255	0.16916784356757
GO:0008266	poly(U) RNA binding	3/458	27/18639	0.111111111111111	4.52183406113537	0.0278495150783803	0.16916784356757
GO:0008320	protein transmembrane transporter activity	3/458	27/18639	0.111111111111111	4.52183406113537	0.0278495150783803	0.16916784356757
GO:0002162	dystroglycan binding	2/458	11/18639	0.181818181818182	7.39936482731243	0.028613534016961	0.16916784356757
GO:0005536	D-glucose binding	2/458	11/18639	0.181818181818182	7.39936482731243	0.028613534016961	0.16916784356757
GO:0010854	adenylate cyclase regulator activity	2/458	11/18639	0.181818181818182	7.39936482731243	0.028613534016961	0.16916784356757
GO:0045294	alpha-catenin binding	2/458	11/18639	0.181818181818182	7.39936482731243	0.028613534016961	0.16916784356757
GO:0050786	RAGE receptor binding	2/458	11/18639	0.181818181818182	7.39936482731243	0.028613534016961	0.16916784356757
GO:0050998	nitric-oxide synthase binding	2/458	11/18639	0.181818181818182	7.39936482731243	0.028613534016961	0.16916784356757
GO:0070990	snRNP binding	2/458	11/18639	0.181818181818182	7.39936482731243	0.028613534016961	0.16916784356757
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/458	11/18639	0.181818181818182	7.39936482731243	0.028613534016961	0.16916784356757
GO:1990948	ubiquitin ligase inhibitor activity	2/458	11/18639	0.181818181818182	7.39936482731243	0.028613534016961	0.16916784356757
GO:0008028	monocarboxylic acid transmembrane transporter activity	5/458	70/18639	0.0714285714285714	2.9068933250156	0.0287945265646928	0.16916784356757
GO:0003714	transcription corepressor activity	10/458	204/18639	0.0490196078431373	1.99492679167737	0.0297180218422441	0.172112730517561
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	4/458	48/18639	0.0833333333333333	3.39137554585153	0.0299241828579826	0.172112730517561
GO:0019209	kinase activator activity	8/458	148/18639	0.0540540540540541	2.19981116487667	0.0299824038534581	0.172112730517561
GO:0140297	DNA-binding transcription factor binding	19/458	488/18639	0.0389344262295082	1.58449513207817	0.0333628830950066	0.186819742678141
GO:0051861	glycolipid binding	3/458	29/18639	0.103448275862069	4.20998343622948	0.033566762995126	0.186819742678141
GO:0106222	lncRNA binding	3/458	29/18639	0.103448275862069	4.20998343622948	0.033566762995126	0.186819742678141
GO:0010853	cyclase activator activity	2/458	12/18639	0.166666666666667	6.78275109170306	0.0337865492077489	0.186819742678141
GO:0017166	vinculin binding	2/458	12/18639	0.166666666666667	6.78275109170306	0.0337865492077489	0.186819742678141
GO:0008514	organic anion transmembrane transporter activity	12/458	269/18639	0.0446096654275093	1.81545754127368	0.0346235957924391	0.190050686393534
GO:0003743	translation initiation factor activity	4/458	51/18639	0.0784313725490196	3.19188286668379	0.0363125825086068	0.19401585254685
GO:0001968	fibronectin binding	3/458	30/18639	0.1	4.06965065502183	0.036635972156453	0.19401585254685
GO:0016769	transferase activity, transferring nitrogenous groups	3/458	30/18639	0.1	4.06965065502183	0.036635972156453	0.19401585254685
GO:0035925	mRNA 3'-UTR AU-rich region binding	3/458	30/18639	0.1	4.06965065502183	0.036635972156453	0.19401585254685
GO:0098918	structural constituent of synapse	3/458	30/18639	0.1	4.06965065502183	0.036635972156453	0.19401585254685
GO:0042826	histone deacetylase binding	7/458	127/18639	0.0551181102362205	2.243114534264	0.0374042439252394	0.196699240781679
GO:0061135	endopeptidase regulator activity	9/458	184/18639	0.0489130434782609	1.99058999430416	0.038436149959726	0.199644249695337
GO:0098631	cell adhesion mediator activity	5/458	76/18639	0.0657894736842105	2.67740174672489	0.0390824163694511	0.199644249695337
GO:0031432	titin binding	2/458	13/18639	0.153846153846154	6.2610010077259	0.0392916874400397	0.199644249695337
GO:0039706	co-receptor binding	2/458	13/18639	0.153846153846154	6.2610010077259	0.0392916874400397	0.199644249695337
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/458	13/18639	0.153846153846154	6.2610010077259	0.0392916874400397	0.199644249695337
GO:0031072	heat shock protein binding	7/458	131/18639	0.0534351145038168	2.17462248741625	0.0430588400761155	0.21344730946581
GO:0046943	carboxylic acid transmembrane transporter activity	9/458	188/18639	0.0478723404255319	1.94823701570194	0.0430881654137642	0.21344730946581
GO:0022884	macromolecule transmembrane transporter activity	3/458	32/18639	0.09375	3.81529748908297	0.0431894323344981	0.21344730946581
GO:0042910	xenobiotic transmembrane transporter activity	3/458	32/18639	0.09375	3.81529748908297	0.0431894323344981	0.21344730946581
GO:0017069	snRNA binding	4/458	54/18639	0.0740740740740741	3.01455604075691	0.0434274446120598	0.21344730946581
GO:0005342	organic acid transmembrane transporter activity	9/458	189/18639	0.0476190476190476	1.93792888334373	0.0443077338895628	0.216359843408774
GO:0008559	ABC-type xenobiotic transporter activity	2/458	14/18639	0.142857142857143	5.81378665003119	0.0451095795525411	0.217451306560967
GO:1990825	sequence-specific mRNA binding	2/458	14/18639	0.142857142857143	5.81378665003119	0.0451095795525411	0.217451306560967
GO:0004866	endopeptidase inhibitor activity	8/458	161/18639	0.0496894409937888	2.02218666088041	0.0456480989119062	0.21864567122136
GO:0098632	cell-cell adhesion mediator activity	4/458	55/18639	0.0727272727272727	2.95974593092497	0.0459607789773551	0.218750036651715
GO:0140416	transcription regulator inhibitor activity	3/458	33/18639	0.0909090909090909	3.69968241365621	0.0466706266005476	0.220731517003848
GO:0030170	pyridoxal phosphate binding	4/458	56/18639	0.0714285714285714	2.9068933250156	0.04857480837646	0.228301599369362
GO:0015101	organic cation transmembrane transporter activity	5/458	81/18639	0.0617283950617284	2.51213003396409	0.049167441467358	0.229651652071138
GO:0008376	acetylgalactosaminyltransferase activity	3/458	34/18639	0.0882352941176471	3.59086822501927	0.0502857909510365	0.231993342301715
GO:0090482	vitamin transmembrane transporter activity	3/458	34/18639	0.0882352941176471	3.59086822501927	0.0502857909510365	0.231993342301715
GO:0055105	ubiquitin-protein transferase inhibitor activity	2/458	15/18639	0.133333333333333	5.42620087336245	0.0512216041063398	0.233663826501814
GO:0070279	vitamin B6 binding	4/458	57/18639	0.0701754385964912	2.85589519650655	0.0512693236340416	0.233663826501814
GO:0008135	translation factor activity, RNA binding	5/458	83/18639	0.0602409638554217	2.45159678013363	0.0535920219654267	0.242778316373499
GO:0016758	hexosyltransferase activity	9/458	197/18639	0.0456852791878173	1.85923126371556	0.054899749549455	0.247213243480181
GO:0180051	translation factor activity	5/458	84/18639	0.0595238095238095	2.42241110417966	0.0558882634988278	0.249667944766859
GO:0070063	RNA polymerase binding	4/458	59/18639	0.0677966101694915	2.75908518984531	0.0568986179243482	0.249667944766859
GO:0030414	peptidase inhibitor activity	8/458	169/18639	0.0473372781065089	1.92646184853105	0.0575515789403069	0.249667944766859
GO:0008142	oxysterol binding	2/458	16/18639	0.125	5.08706331877729	0.0576098624649909	0.249667944766859
GO:0017070	U6 snRNA binding	2/458	16/18639	0.125	5.08706331877729	0.0576098624649909	0.249667944766859
GO:0097027	ubiquitin-protein transferase activator activity	2/458	16/18639	0.125	5.08706331877729	0.0576098624649909	0.249667944766859
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/458	36/18639	0.0833333333333333	3.39137554585153	0.0579100425240381	0.249667944766859
GO:0043022	ribosome binding	6/458	112/18639	0.0535714285714286	2.1801699937617	0.0581009179976069	0.249667944766859
GO:0016829	lyase activity	9/458	200/18639	0.045	1.83134279475983	0.0592621435313773	0.252776045952509
GO:0001098	basal transcription machinery binding	4/458	60/18639	0.0666666666666667	2.71310043668122	0.0598326278983333	0.252776045952509
GO:0001099	basal RNA polymerase II transcription machinery binding	4/458	60/18639	0.0666666666666667	2.71310043668122	0.0598326278983333	0.252776045952509
GO:0016018	cyclosporin A binding	2/458	17/18639	0.117647058823529	4.78782430002569	0.0642571546435723	0.266968951889317
GO:0046965	nuclear retinoid X receptor binding	2/458	17/18639	0.117647058823529	4.78782430002569	0.0642571546435723	0.266968951889317
GO:0070492	oligosaccharide binding	2/458	17/18639	0.117647058823529	4.78782430002569	0.0642571546435723	0.266968951889317
GO:0042162	telomeric DNA binding	3/458	38/18639	0.0789473684210526	3.21288209606987	0.0660448023242287	0.272888413999011
GO:0015293	symporter activity	7/458	146/18639	0.0479452054794521	1.95120236884608	0.0690166350906797	0.283609342011974
GO:0005516	calmodulin binding	9/458	207/18639	0.0434782608695652	1.76941332827036	0.070287406319151	0.287261573652182
GO:0000400	four-way junction DNA binding	2/458	18/18639	0.111111111111111	4.52183406113537	0.0711469559040903	0.287647907741268
GO:0031690	adrenergic receptor binding	2/458	18/18639	0.111111111111111	4.52183406113537	0.0711469559040903	0.287647907741268
GO:0004175	endopeptidase activity	15/458	405/18639	0.037037037037037	1.50727802037846	0.0761514953397074	0.306234890350053
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/458	19/18639	0.105263157894737	4.28384279475982	0.0782633940752619	0.308136504421974
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	2/458	19/18639	0.105263157894737	4.28384279475982	0.0782633940752619	0.308136504421974
GO:0030506	ankyrin binding	2/458	19/18639	0.105263157894737	4.28384279475982	0.0782633940752619	0.308136504421974
GO:0046624	sphingolipid transporter activity	2/458	19/18639	0.105263157894737	4.28384279475982	0.0782633940752619	0.308136504421974
GO:0140318	protein transporter activity	3/458	41/18639	0.0731707317073171	2.9777931622111	0.0791613019024712	0.310048432451345
GO:0008017	microtubule binding	11/458	276/18639	0.0398550724637681	1.62196221758117	0.0796560688846292	0.310369760628192
GO:0050840	extracellular matrix binding	4/458	67/18639	0.0597014925373134	2.42964218210259	0.0825465856697216	0.319759181677615
GO:0008307	structural constituent of muscle	3/458	42/18639	0.0714285714285714	2.9068933250156	0.0837667005192689	0.319759181677615
GO:0031492	nucleosomal DNA binding	3/458	42/18639	0.0714285714285714	2.9068933250156	0.0837667005192689	0.319759181677615
GO:0048487	beta-tubulin binding	3/458	42/18639	0.0714285714285714	2.9068933250156	0.0837667005192689	0.319759181677615
GO:0010851	cyclase regulator activity	2/458	20/18639	0.1	4.06965065502183	0.0855912275753278	0.322101579253406
GO:0042288	MHC class I protein binding	2/458	20/18639	0.1	4.06965065502183	0.0855912275753278	0.322101579253406
GO:0030246	carbohydrate binding	11/458	280/18639	0.0392857142857143	1.59879132875858	0.0860377805237732	0.322101579253406
GO:0030145	manganese ion binding	4/458	68/18639	0.0588235294117647	2.39391215001284	0.0860936401993811	0.322101579253406
GO:0015078	proton transmembrane transporter activity	8/458	185/18639	0.0432432432432432	1.75984893190133	0.0867949787846335	0.323117940822002
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	13/458	349/18639	0.0372492836676218	1.51591571677031	0.0908960069263651	0.335543221070335
GO:0031267	small GTPase binding	11/458	283/18639	0.03886925795053	1.58184301078587	0.0910250227371655	0.335543221070335
GO:0140597	protein carrier chaperone	8/458	188/18639	0.0425531914893617	1.7317662361795	0.0930931830736756	0.338275844135757
GO:0001846	opsonin binding	2/458	21/18639	0.0952380952380952	3.87585776668746	0.0931158241171566	0.338275844135757
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/458	21/18639	0.0952380952380952	3.87585776668746	0.0931158241171566	0.338275844135757
GO:0042626	ATPase-coupled transmembrane transporter activity	5/458	98/18639	0.0510204081632653	2.07635237501114	0.0938404637687165	0.339269369009975
GO:0042605	peptide antigen binding	3/458	45/18639	0.0666666666666667	2.71310043668122	0.0982430058484178	0.353486796162728
GO:0003713	transcription coactivator activity	10/458	256/18639	0.0390625	1.5897072871179	0.101227737981404	0.362491709342933
GO:0015171	amino acid transmembrane transporter activity	5/458	102/18639	0.0490196078431373	1.99492679167737	0.106609734507055	0.379040513991927
GO:0005504	fatty acid binding	3/458	47/18639	0.0638297872340425	2.59764935426926	0.108414334643916	0.379040513991927
GO:0004602	glutathione peroxidase activity	2/458	23/18639	0.0869565217391304	3.53882665654073	0.108699700496784	0.379040513991927
GO:0031681	G-protein beta-subunit binding	2/458	23/18639	0.0869565217391304	3.53882665654073	0.108699700496784	0.379040513991927
GO:0043274	phospholipase binding	2/458	23/18639	0.0869565217391304	3.53882665654073	0.108699700496784	0.379040513991927
GO:0048029	monosaccharide binding	4/458	74/18639	0.0540540540540541	2.19981116487667	0.108873339125341	0.379040513991927
GO:0140713	histone chaperone activity	7/458	164/18639	0.0426829268292683	1.73704601128981	0.110274715618229	0.382150166566398
GO:0140693	molecular condensate scaffold activity	3/458	48/18639	0.0625	2.54353165938865	0.113647011429645	0.392030057775656
GO:0015149	hexose transmembrane transporter activity	2/458	24/18639	0.0833333333333333	3.39137554585153	0.116732579732545	0.3972076921216
GO:0015295	solute:proton symporter activity	2/458	24/18639	0.0833333333333333	3.39137554585153	0.116732579732545	0.3972076921216
GO:0055056	D-glucose transmembrane transporter activity	2/458	24/18639	0.0833333333333333	3.39137554585153	0.116732579732545	0.3972076921216
GO:0002020	protease binding	6/458	136/18639	0.0441176470588235	1.79543411250963	0.118902388307082	0.402768450481646
GO:0003724	RNA helicase activity	4/458	77/18639	0.051948051948052	2.11410423637498	0.121176620312327	0.408399372929276
GO:0016922	nuclear receptor binding	6/458	137/18639	0.0437956204379562	1.78232875402416	0.121942383377278	0.408399372929276
GO:0016757	glycosyltransferase activity	10/458	267/18639	0.0374531835205993	1.5242137284726	0.123658801648473	0.408399372929276
GO:0046982	protein heterodimerization activity	13/458	369/18639	0.035230352303523	1.43375226328682	0.124247612603738	0.408399372929276
GO:0001848	complement binding	2/458	25/18639	0.08	3.25572052401747	0.124909382677837	0.408399372929276
GO:0008139	nuclear localization sequence binding	2/458	25/18639	0.08	3.25572052401747	0.124909382677837	0.408399372929276
GO:0015662	P-type ion transporter activity	2/458	25/18639	0.08	3.25572052401747	0.124909382677837	0.408399372929276
GO:0140358	P-type transmembrane transporter activity	2/458	25/18639	0.08	3.25572052401747	0.124909382677837	0.408399372929276
GO:0008186	ATP-dependent activity, acting on RNA	4/458	79/18639	0.0506329113924051	2.06058261013764	0.12969516665334	0.41858697563653
GO:0016835	carbon-oxygen lyase activity	4/458	79/18639	0.0506329113924051	2.06058261013764	0.12969516665334	0.41858697563653
GO:0033293	monocarboxylic acid binding	4/458	79/18639	0.0506329113924051	2.06058261013764	0.12969516665334	0.41858697563653
GO:0008201	heparin binding	7/458	172/18639	0.0406976744186047	1.6562531735554	0.132043349845201	0.419163625108161
GO:0008143	poly(A) binding	2/458	26/18639	0.0769230769230769	3.13050050386295	0.133218226596876	0.419163625108161
GO:0015145	monosaccharide transmembrane transporter activity	2/458	26/18639	0.0769230769230769	3.13050050386295	0.133218226596876	0.419163625108161
GO:0034237	protein kinase A regulatory subunit binding	2/458	26/18639	0.0769230769230769	3.13050050386295	0.133218226596876	0.419163625108161
GO:0050681	nuclear androgen receptor binding	2/458	26/18639	0.0769230769230769	3.13050050386295	0.133218226596876	0.419163625108161
GO:0050750	low-density lipoprotein particle receptor binding	2/458	26/18639	0.0769230769230769	3.13050050386295	0.133218226596876	0.419163625108161
GO:0048306	calcium-dependent protein binding	4/458	80/18639	0.05	2.03482532751092	0.134045488890647	0.420009198524026
GO:0005080	protein kinase C binding	3/458	52/18639	0.0576923076923077	2.34787537789721	0.135485081115281	0.422758427380461
GO:0001618	virus receptor activity	4/458	81/18639	0.0493827160493827	2.00970402717128	0.138454738107441	0.430239516763618
GO:0004864	protein phosphatase inhibitor activity	3/458	53/18639	0.0566037735849057	2.30357584246519	0.141155689550183	0.434771788105319
GO:0140296	general transcription initiation factor binding	3/458	53/18639	0.0566037735849057	2.30357584246519	0.141155689550183	0.434771788105319
GO:0004364	glutathione transferase activity	2/458	27/18639	0.0740740740740741	3.01455604075691	0.141647723518355	0.434771788105319
GO:0140272	exogenous protein binding	4/458	82/18639	0.0487804878048781	1.98519544147407	0.142921557913874	0.436898420939974
GO:0008094	ATP-dependent activity, acting on DNA	8/458	210/18639	0.0380952380952381	1.55034310667498	0.146895895687707	0.441888464800707
GO:0015485	cholesterol binding	3/458	54/18639	0.0555555555555556	2.26091703056769	0.14690440984066	0.441888464800707
GO:0051287	NAD binding	3/458	54/18639	0.0555555555555556	2.26091703056769	0.14690440984066	0.441888464800707
GO:0140463	chromatin-protein adaptor activity	3/458	54/18639	0.0555555555555556	2.26091703056769	0.14690440984066	0.441888464800707
GO:0051119	sugar transmembrane transporter activity	2/458	28/18639	0.0714285714285714	2.9068933250156	0.150186963183568	0.449962535115709
GO:0140313	molecular sequestering activity	3/458	55/18639	0.0545454545454545	2.21980944819373	0.152728080852005	0.455759987304396
GO:0003785	actin monomer binding	2/458	29/18639	0.0689655172413793	2.80665562415299	0.15882549653086	0.470223517288215
GO:0043236	laminin binding	2/458	29/18639	0.0689655172413793	2.80665562415299	0.15882549653086	0.470223517288215
GO:0016504	peptidase activator activity	3/458	57/18639	0.0526315789473684	2.14192139737991	0.164587672742632	0.484027537566783
GO:0019842	vitamin binding	6/458	150/18639	0.04	1.62786026200873	0.164775331937628	0.484027537566783
GO:0015291	secondary active transmembrane transporter activity	10/458	287/18639	0.0348432055749129	1.41799674391005	0.17074443641349	0.499610179700172
GO:0032182	ubiquitin-like protein binding	5/458	120/18639	0.0416666666666667	1.69568777292576	0.17342709773518	0.505492936034323
GO:0070325	lipoprotein particle receptor binding	2/458	31/18639	0.0645161290322581	2.62558106775602	0.176360858544165	0.511097953568146
GO:0045309	protein phosphorylated amino acid binding	3/458	59/18639	0.0508474576271186	2.06931389238398	0.176709398840051	0.511097953568146
GO:0031369	translation initiation factor binding	2/458	32/18639	0.0625	2.54353165938865	0.18523895362481	0.531678218037622
GO:0070717	poly-purine tract binding	2/458	32/18639	0.0625	2.54353165938865	0.18523895362481	0.531678218037622
GO:0043178	alcohol binding	4/458	92/18639	0.0434782608695652	1.76941332827036	0.190445937102895	0.544545036887366
GO:0140658	ATP-dependent chromatin remodeler activity	6/458	158/18639	0.0379746835443038	1.54543695760323	0.193902308546485	0.550486859428237
GO:0019956	chemokine binding	2/458	33/18639	0.0606060606060606	2.46645494243748	0.194178845690891	0.550486859428237
GO:0015179	L-amino acid transmembrane transporter activity	3/458	62/18639	0.0483870967741935	1.96918580081702	0.195329416996732	0.550486859428237
GO:0051219	phosphoprotein binding	4/458	93/18639	0.043010752688172	1.75038737850401	0.195452116312951	0.550486859428237
GO:0005507	copper ion binding	3/458	63/18639	0.0476190476190476	1.93792888334373	0.201640581762464	0.563694117045997
GO:1901682	sulfur compound transmembrane transporter activity	3/458	63/18639	0.0476190476190476	1.93792888334373	0.201640581762464	0.563694117045997
GO:0016831	carboxy-lyase activity	2/458	34/18639	0.0588235294117647	2.39391215001284	0.203172161612132	0.565872094564161
GO:0031490	chromatin DNA binding	5/458	128/18639	0.0390625	1.5897072871179	0.207277204020424	0.566014085782059
GO:0008083	growth factor activity	6/458	162/18639	0.037037037037037	1.50727802037846	0.209150668586549	0.566014085782059
GO:0043015	gamma-tubulin binding	2/458	35/18639	0.0571428571428571	2.32551466001248	0.212210900762176	0.566014085782059
GO:0061631	ubiquitin conjugating enzyme activity	2/458	35/18639	0.0571428571428571	2.32551466001248	0.212210900762176	0.566014085782059
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/458	10/18639	0.1	4.06965065502183	0.22030425805515	0.566014085782059
GO:0005381	iron ion transmembrane transporter activity	1/458	10/18639	0.1	4.06965065502183	0.22030425805515	0.566014085782059
GO:0005522	profilin binding	1/458	10/18639	0.1	4.06965065502183	0.22030425805515	0.566014085782059
GO:0008190	eukaryotic initiation factor 4E binding	1/458	10/18639	0.1	4.06965065502183	0.22030425805515	0.566014085782059
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/458	10/18639	0.1	4.06965065502183	0.22030425805515	0.566014085782059
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/458	10/18639	0.1	4.06965065502183	0.22030425805515	0.566014085782059
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/458	10/18639	0.1	4.06965065502183	0.22030425805515	0.566014085782059
GO:0016427	tRNA (cytidine) methyltransferase activity	1/458	10/18639	0.1	4.06965065502183	0.22030425805515	0.566014085782059
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/458	10/18639	0.1	4.06965065502183	0.22030425805515	0.566014085782059
GO:0032052	bile acid binding	1/458	10/18639	0.1	4.06965065502183	0.22030425805515	0.566014085782059
GO:0042975	peroxisome proliferator activated receptor binding	1/458	10/18639	0.1	4.06965065502183	0.22030425805515	0.566014085782059
GO:0097177	mitochondrial ribosome binding	1/458	10/18639	0.1	4.06965065502183	0.22030425805515	0.566014085782059
GO:0098505	G-rich strand telomeric DNA binding	1/458	10/18639	0.1	4.06965065502183	0.22030425805515	0.566014085782059
GO:0099122	RNA polymerase II C-terminal domain binding	1/458	10/18639	0.1	4.06965065502183	0.22030425805515	0.566014085782059
GO:0140135	mechanosensitive monoatomic cation channel activity	1/458	10/18639	0.1	4.06965065502183	0.22030425805515	0.566014085782059
GO:1990757	ubiquitin ligase activator activity	1/458	10/18639	0.1	4.06965065502183	0.22030425805515	0.566014085782059
GO:0000993	RNA polymerase II complex binding	2/458	36/18639	0.0555555555555556	2.26091703056769	0.221287421835007	0.566014085782059
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	2/458	36/18639	0.0555555555555556	2.26091703056769	0.221287421835007	0.566014085782059
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	2/458	36/18639	0.0555555555555556	2.26091703056769	0.221287421835007	0.566014085782059
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	2/458	36/18639	0.0555555555555556	2.26091703056769	0.221287421835007	0.566014085782059
GO:0043130	ubiquitin binding	4/458	100/18639	0.04	1.62786026200873	0.231538827551741	0.577316582205303
GO:0032934	sterol binding	3/458	68/18639	0.0441176470588235	1.79543411250963	0.233847321015649	0.577316582205303
GO:1901681	sulfur compound binding	9/458	275/18639	0.0327272727272727	1.33188566891624	0.236713337188513	0.577316582205303
GO:0000099	sulfur amino acid transmembrane transporter activity	1/458	11/18639	0.0909090909090909	3.69968241365621	0.239473330458969	0.577316582205303
GO:0008199	ferric iron binding	1/458	11/18639	0.0909090909090909	3.69968241365621	0.239473330458969	0.577316582205303
GO:0015173	aromatic amino acid transmembrane transporter activity	1/458	11/18639	0.0909090909090909	3.69968241365621	0.239473330458969	0.577316582205303
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/458	11/18639	0.0909090909090909	3.69968241365621	0.239473330458969	0.577316582205303
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/458	11/18639	0.0909090909090909	3.69968241365621	0.239473330458969	0.577316582205303
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/458	11/18639	0.0909090909090909	3.69968241365621	0.239473330458969	0.577316582205303
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/458	11/18639	0.0909090909090909	3.69968241365621	0.239473330458969	0.577316582205303
GO:0032794	GTPase activating protein binding	1/458	11/18639	0.0909090909090909	3.69968241365621	0.239473330458969	0.577316582205303
GO:0034056	estrogen response element binding	1/458	11/18639	0.0909090909090909	3.69968241365621	0.239473330458969	0.577316582205303
GO:0034511	U3 snoRNA binding	1/458	11/18639	0.0909090909090909	3.69968241365621	0.239473330458969	0.577316582205303
GO:0034713	type I transforming growth factor beta receptor binding	1/458	11/18639	0.0909090909090909	3.69968241365621	0.239473330458969	0.577316582205303
GO:0048185	activin binding	1/458	11/18639	0.0909090909090909	3.69968241365621	0.239473330458969	0.577316582205303
GO:0097493	structural molecule activity conferring elasticity	1/458	11/18639	0.0909090909090909	3.69968241365621	0.239473330458969	0.577316582205303
GO:0000146	microfilament motor activity	2/458	38/18639	0.0526315789473684	2.14192139737991	0.239524964957519	0.577316582205303
GO:0043531	ADP binding	2/458	38/18639	0.0526315789473684	2.14192139737991	0.239524964957519	0.577316582205303
GO:0005543	phospholipid binding	15/458	497/18639	0.0301810865191147	1.22826478521786	0.243098825274152	0.577394301330883
GO:0097110	scaffold protein binding	3/458	70/18639	0.0428571428571429	1.74413599500936	0.246980629913703	0.577394301330883
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	2/458	39/18639	0.0512820512820513	2.08700033590863	0.248672388159065	0.577394301330883
GO:0015144	carbohydrate transmembrane transporter activity	2/458	40/18639	0.05	2.03482532751092	0.257830372052932	0.577394301330883
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	2/458	40/18639	0.05	2.03482532751092	0.257830372052932	0.577394301330883
GO:0030331	nuclear estrogen receptor binding	2/458	40/18639	0.05	2.03482532751092	0.257830372052932	0.577394301330883
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	2/458	40/18639	0.05	2.03482532751092	0.257830372052932	0.577394301330883
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/458	12/18639	0.0833333333333333	3.39137554585153	0.258172128754534	0.577394301330883
GO:0005078	MAP-kinase scaffold activity	1/458	12/18639	0.0833333333333333	3.39137554585153	0.258172128754534	0.577394301330883
GO:0005095	GTPase inhibitor activity	1/458	12/18639	0.0833333333333333	3.39137554585153	0.258172128754534	0.577394301330883
GO:0005165	neurotrophin receptor binding	1/458	12/18639	0.0833333333333333	3.39137554585153	0.258172128754534	0.577394301330883
GO:0008179	adenylate cyclase binding	1/458	12/18639	0.0833333333333333	3.39137554585153	0.258172128754534	0.577394301330883
GO:0008603	cAMP-dependent protein kinase regulator activity	1/458	12/18639	0.0833333333333333	3.39137554585153	0.258172128754534	0.577394301330883
GO:0015132	prostaglandin transmembrane transporter activity	1/458	12/18639	0.0833333333333333	3.39137554585153	0.258172128754534	0.577394301330883
GO:0016208	AMP binding	1/458	12/18639	0.0833333333333333	3.39137554585153	0.258172128754534	0.577394301330883
GO:0016801	hydrolase activity, acting on ether bonds	1/458	12/18639	0.0833333333333333	3.39137554585153	0.258172128754534	0.577394301330883
GO:0016803	ether hydrolase activity	1/458	12/18639	0.0833333333333333	3.39137554585153	0.258172128754534	0.577394301330883
GO:0035251	UDP-glucosyltransferase activity	1/458	12/18639	0.0833333333333333	3.39137554585153	0.258172128754534	0.577394301330883
GO:0035259	nuclear glucocorticoid receptor binding	1/458	12/18639	0.0833333333333333	3.39137554585153	0.258172128754534	0.577394301330883
GO:0043047	single-stranded telomeric DNA binding	1/458	12/18639	0.0833333333333333	3.39137554585153	0.258172128754534	0.577394301330883
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/458	12/18639	0.0833333333333333	3.39137554585153	0.258172128754534	0.577394301330883
GO:0097371	MDM2/MDM4 family protein binding	1/458	12/18639	0.0833333333333333	3.39137554585153	0.258172128754534	0.577394301330883
GO:0035091	phosphatidylinositol binding	9/458	284/18639	0.0316901408450704	1.28967802447875	0.265380306596444	0.577394301330883
GO:0008137	NADH dehydrogenase (ubiquinone) activity	2/458	41/18639	0.0487804878048781	1.98519544147407	0.266992888470904	0.577394301330883
GO:0042287	MHC protein binding	2/458	41/18639	0.0487804878048781	1.98519544147407	0.266992888470904	0.577394301330883
GO:0061650	ubiquitin-like protein conjugating enzyme activity	2/458	41/18639	0.0487804878048781	1.98519544147407	0.266992888470904	0.577394301330883
GO:0031491	nucleosome binding	3/458	74/18639	0.0405405405405405	1.6498583736575	0.273557205321893	0.577394301330883
GO:0005319	lipid transporter activity	6/458	178/18639	0.0337078651685393	1.37179235562534	0.27382283597974	0.577394301330883
GO:0016859	cis-trans isomerase activity	2/458	42/18639	0.0476190476190476	1.93792888334373	0.276154197868486	0.577394301330883
GO:0043175	RNA polymerase core enzyme binding	2/458	42/18639	0.0476190476190476	1.93792888334373	0.276154197868486	0.577394301330883
GO:0051879	Hsp90 protein binding	2/458	42/18639	0.0476190476190476	1.93792888334373	0.276154197868486	0.577394301330883
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0005172	vascular endothelial growth factor receptor binding	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0008035	high-density lipoprotein particle binding	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0008253	5'-nucleotidase activity	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0019855	calcium channel inhibitor activity	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0030955	potassium ion binding	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0045159	myosin II binding	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0051011	microtubule minus-end binding	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0061459	L-arginine transmembrane transporter activity	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0070700	BMP receptor binding	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0071714	icosanoid transmembrane transporter activity	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0097157	pre-mRNA intronic binding	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0140333	glycerophospholipid flippase activity	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0140852	histone ubiquitin ligase activity	1/458	13/18639	0.0769230769230769	3.13050050386295	0.276412165530742	0.577394301330883
GO:0019903	protein phosphatase binding	5/458	144/18639	0.0347222222222222	1.4130731441048	0.280351516479502	0.584000942915748
GO:0008194	UDP-glycosyltransferase activity	5/458	145/18639	0.0344827586206897	1.40332781207649	0.28509267060403	0.589429249457524
GO:0004712	protein serine/threonine/tyrosine kinase activity	2/458	43/18639	0.0465116279069767	1.8928607697776	0.285308838833163	0.589429249457524
GO:0008200	ion channel inhibitor activity	2/458	43/18639	0.0465116279069767	1.8928607697776	0.285308838833163	0.589429249457524
GO:0005545	1-phosphatidylinositol binding	1/458	14/18639	0.0714285714285714	2.9068933250156	0.294204672144449	0.590473644493343
GO:0008174	mRNA methyltransferase activity	1/458	14/18639	0.0714285714285714	2.9068933250156	0.294204672144449	0.590473644493343
GO:0008191	metalloendopeptidase inhibitor activity	1/458	14/18639	0.0714285714285714	2.9068933250156	0.294204672144449	0.590473644493343
GO:0032036	myosin heavy chain binding	1/458	14/18639	0.0714285714285714	2.9068933250156	0.294204672144449	0.590473644493343
GO:0034236	protein kinase A catalytic subunit binding	1/458	14/18639	0.0714285714285714	2.9068933250156	0.294204672144449	0.590473644493343
GO:0070742	C2H2 zinc finger domain binding	1/458	14/18639	0.0714285714285714	2.9068933250156	0.294204672144449	0.590473644493343
GO:0098847	sequence-specific single stranded DNA binding	1/458	14/18639	0.0714285714285714	2.9068933250156	0.294204672144449	0.590473644493343
GO:0003954	NADH dehydrogenase activity	2/458	44/18639	0.0454545454545455	1.84984120682811	0.294451617932186	0.590473644493343
GO:0016248	channel inhibitor activity	2/458	44/18639	0.0454545454545455	1.84984120682811	0.294451617932186	0.590473644493343
GO:0030547	signaling receptor inhibitor activity	2/458	44/18639	0.0454545454545455	1.84984120682811	0.294451617932186	0.590473644493343
GO:0043014	alpha-tubulin binding	2/458	44/18639	0.0454545454545455	1.84984120682811	0.294451617932186	0.590473644493343
GO:1901981	phosphatidylinositol phosphate binding	6/458	185/18639	0.0324324324324324	1.319886698926	0.303518158764808	0.593810030402831
GO:0046915	transition metal ion transmembrane transporter activity	2/458	45/18639	0.0444444444444444	1.80873362445415	0.30357759988957	0.593810030402831
GO:0141110	transporter inhibitor activity	2/458	45/18639	0.0444444444444444	1.80873362445415	0.30357759988957	0.593810030402831
GO:0004559	alpha-mannosidase activity	1/458	15/18639	0.0666666666666667	2.71310043668122	0.311560605575743	0.593810030402831
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/458	15/18639	0.0666666666666667	2.71310043668122	0.311560605575743	0.593810030402831
GO:0008242	omega peptidase activity	1/458	15/18639	0.0666666666666667	2.71310043668122	0.311560605575743	0.593810030402831
GO:0008252	nucleotidase activity	1/458	15/18639	0.0666666666666667	2.71310043668122	0.311560605575743	0.593810030402831
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/458	15/18639	0.0666666666666667	2.71310043668122	0.311560605575743	0.593810030402831
GO:0016846	carbon-sulfur lyase activity	1/458	15/18639	0.0666666666666667	2.71310043668122	0.311560605575743	0.593810030402831
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/458	15/18639	0.0666666666666667	2.71310043668122	0.311560605575743	0.593810030402831
GO:0033130	acetylcholine receptor binding	1/458	15/18639	0.0666666666666667	2.71310043668122	0.311560605575743	0.593810030402831
GO:0050700	CARD domain binding	1/458	15/18639	0.0666666666666667	2.71310043668122	0.311560605575743	0.593810030402831
GO:0120283	protein serine/threonine kinase binding	1/458	15/18639	0.0666666666666667	2.71310043668122	0.311560605575743	0.593810030402831
GO:0140776	protein-containing complex destabilizing activity	1/458	15/18639	0.0666666666666667	2.71310043668122	0.311560605575743	0.593810030402831
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	2/458	46/18639	0.0434782608695652	1.76941332827036	0.312682098082336	0.593810030402831
GO:0030291	protein serine/threonine kinase inhibitor activity	2/458	46/18639	0.0434782608695652	1.76941332827036	0.312682098082336	0.593810030402831
GO:0140097	catalytic activity, acting on DNA	10/458	336/18639	0.0297619047619048	1.21120555208983	0.313531703588035	0.593810030402831
GO:0000510	H3-H4 histone complex chaperone activity	5/458	151/18639	0.033112582781457	1.34756644206021	0.313825336268865	0.593810030402831
GO:0140584	chromatin extrusion motor activity	5/458	151/18639	0.033112582781457	1.34756644206021	0.313825336268865	0.593810030402831
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	5/458	151/18639	0.033112582781457	1.34756644206021	0.313825336268865	0.593810030402831
GO:0140849	ATP-dependent H2AZ histone chaperone activity	5/458	151/18639	0.033112582781457	1.34756644206021	0.313825336268865	0.593810030402831
GO:0000049	tRNA binding	3/458	80/18639	0.0375	1.52611899563319	0.313894403647754	0.593810030402831
GO:0015616	DNA translocase activity	5/458	152/18639	0.0328947368421053	1.33870087336245	0.318653590881968	0.593810030402831
GO:0140674	ATP-dependent histone chaperone activity	5/458	152/18639	0.0328947368421053	1.33870087336245	0.318653590881968	0.593810030402831
GO:0015294	solute:monoatomic cation symporter activity	4/458	116/18639	0.0344827586206897	1.40332781207649	0.318733034367245	0.593810030402831
GO:0001784	phosphotyrosine residue binding	2/458	47/18639	0.0425531914893617	1.7317662361795	0.321760665346266	0.593810030402831
GO:0140359	ABC-type transporter activity	2/458	47/18639	0.0425531914893617	1.7317662361795	0.321760665346266	0.593810030402831
GO:0061775	cohesin loader activity	5/458	153/18639	0.0326797385620915	1.32995119445158	0.323490831163778	0.593810030402831
GO:0019902	phosphatase binding	6/458	190/18639	0.0315789473684211	1.28515283842795	0.325076101857403	0.593810030402831
GO:0003688	DNA replication origin binding	1/458	16/18639	0.0625	2.54353165938865	0.32849065511646	0.593810030402831
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/458	16/18639	0.0625	2.54353165938865	0.32849065511646	0.593810030402831
GO:0015562	efflux transmembrane transporter activity	1/458	16/18639	0.0625	2.54353165938865	0.32849065511646	0.593810030402831
GO:0015923	mannosidase activity	1/458	16/18639	0.0625	2.54353165938865	0.32849065511646	0.593810030402831
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/458	16/18639	0.0625	2.54353165938865	0.32849065511646	0.593810030402831
GO:0022858	alanine transmembrane transporter activity	1/458	16/18639	0.0625	2.54353165938865	0.32849065511646	0.593810030402831
GO:0034450	ubiquitin-ubiquitin ligase activity	1/458	16/18639	0.0625	2.54353165938865	0.32849065511646	0.593810030402831
GO:0043023	ribosomal large subunit binding	1/458	16/18639	0.0625	2.54353165938865	0.32849065511646	0.593810030402831
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/458	16/18639	0.0625	2.54353165938865	0.32849065511646	0.593810030402831
GO:0070411	I-SMAD binding	1/458	16/18639	0.0625	2.54353165938865	0.32849065511646	0.593810030402831
GO:0140327	flippase activity	1/458	16/18639	0.0625	2.54353165938865	0.32849065511646	0.593810030402831
GO:0140328	floppase activity	1/458	16/18639	0.0625	2.54353165938865	0.32849065511646	0.593810030402831
GO:0004386	helicase activity	5/458	155/18639	0.032258064516129	1.31279053387801	0.33318889254844	0.600858626370328
GO:0005254	chloride channel activity	3/458	83/18639	0.036144578313253	1.47095806808018	0.33413895347215	0.601130366055159
GO:0001222	transcription corepressor binding	2/458	49/18639	0.0408163265306122	1.66108190000891	0.339823362650719	0.609897777358808
GO:0004029	aldehyde dehydrogenase (NAD+) activity	1/458	17/18639	0.0588235294117647	2.39391215001284	0.345005248896015	0.610456346281891
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/458	17/18639	0.0588235294117647	2.39391215001284	0.345005248896015	0.610456346281891
GO:0005092	GDP-dissociation inhibitor activity	1/458	17/18639	0.0588235294117647	2.39391215001284	0.345005248896015	0.610456346281891
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/458	17/18639	0.0588235294117647	2.39391215001284	0.345005248896015	0.610456346281891
GO:0030548	acetylcholine receptor regulator activity	1/458	17/18639	0.0588235294117647	2.39391215001284	0.345005248896015	0.610456346281891
GO:0032183	SUMO binding	1/458	17/18639	0.0588235294117647	2.39391215001284	0.345005248896015	0.610456346281891
GO:0005007	fibroblast growth factor receptor activity	2/458	50/18639	0.04	1.62786026200873	0.348799717055339	0.615721566257311
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/458	122/18639	0.0327868852459016	1.33431169017109	0.352236807101495	0.620332737565161
GO:0003689	DNA clamp loader activity	5/458	160/18639	0.03125	1.27176582969432	0.357532977425689	0.621414529306311
GO:0016830	carbon-carbon lyase activity	2/458	51/18639	0.0392156862745098	1.5959414333419	0.357734572890584	0.621414529306311
GO:0003746	translation elongation factor activity	1/458	18/18639	0.0555555555555556	2.26091703056769	0.361114560248481	0.621414529306311
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	1/458	18/18639	0.0555555555555556	2.26091703056769	0.361114560248481	0.621414529306311
GO:0015172	acidic amino acid transmembrane transporter activity	1/458	18/18639	0.0555555555555556	2.26091703056769	0.361114560248481	0.621414529306311
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/458	18/18639	0.0555555555555556	2.26091703056769	0.361114560248481	0.621414529306311
GO:0034185	apolipoprotein binding	1/458	18/18639	0.0555555555555556	2.26091703056769	0.361114560248481	0.621414529306311
GO:0070064	proline-rich region binding	1/458	18/18639	0.0555555555555556	2.26091703056769	0.361114560248481	0.621414529306311
GO:0098641	cadherin binding involved in cell-cell adhesion	1/458	18/18639	0.0555555555555556	2.26091703056769	0.361114560248481	0.621414529306311
GO:0099602	neurotransmitter receptor regulator activity	1/458	18/18639	0.0555555555555556	2.26091703056769	0.361114560248481	0.621414529306311
GO:0004197	cysteine-type endopeptidase activity	3/458	88/18639	0.0340909090909091	1.38738090512108	0.36779591592788	0.630028539357097
GO:0016651	oxidoreductase activity, acting on NAD(P)H	3/458	88/18639	0.0340909090909091	1.38738090512108	0.36779591592788	0.630028539357097
GO:0005246	calcium channel regulator activity	2/458	53/18639	0.0377358490566038	1.53571722831013	0.375466468758123	0.633948640875678
GO:0017046	peptide hormone binding	2/458	53/18639	0.0377358490566038	1.53571722831013	0.375466468758123	0.633948640875678
GO:0051018	protein kinase A binding	2/458	53/18639	0.0377358490566038	1.53571722831013	0.375466468758123	0.633948640875678
GO:0008381	mechanosensitive monoatomic ion channel activity	1/458	19/18639	0.0526315789473684	2.14192139737991	0.376828513924771	0.633948640875678
GO:0015245	fatty acid transmembrane transporter activity	1/458	19/18639	0.0526315789473684	2.14192139737991	0.376828513924771	0.633948640875678
GO:0031420	alkali metal ion binding	1/458	19/18639	0.0526315789473684	2.14192139737991	0.376828513924771	0.633948640875678
GO:0046527	glucosyltransferase activity	1/458	19/18639	0.0526315789473684	2.14192139737991	0.376828513924771	0.633948640875678
GO:0097001	ceramide binding	1/458	19/18639	0.0526315789473684	2.14192139737991	0.376828513924771	0.633948640875678
GO:0003925	G protein activity	2/458	54/18639	0.037037037037037	1.50727802037846	0.384257317178025	0.643566820752505
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	2/458	54/18639	0.037037037037037	1.50727802037846	0.384257317178025	0.643566820752505
GO:0072341	modified amino acid binding	3/458	91/18639	0.032967032967033	1.34164307308412	0.387856709128524	0.645299579211323
GO:0000339	RNA cap binding	1/458	20/18639	0.05	2.03482532751092	0.39215679215369	0.645299579211323
GO:0015095	magnesium ion transmembrane transporter activity	1/458	20/18639	0.05	2.03482532751092	0.39215679215369	0.645299579211323
GO:0016408	C-acyltransferase activity	1/458	20/18639	0.05	2.03482532751092	0.39215679215369	0.645299579211323
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/458	20/18639	0.05	2.03482532751092	0.39215679215369	0.645299579211323
GO:0030742	GTP-dependent protein binding	1/458	20/18639	0.05	2.03482532751092	0.39215679215369	0.645299579211323
GO:0031418	L-ascorbic acid binding	1/458	20/18639	0.05	2.03482532751092	0.39215679215369	0.645299579211323
GO:0043024	ribosomal small subunit binding	1/458	20/18639	0.05	2.03482532751092	0.39215679215369	0.645299579211323
GO:0170055	lipid transmembrane transporter activity	2/458	56/18639	0.0357142857142857	1.4534466625078	0.40167466654358	0.656985627149672
GO:0042393	histone binding	7/458	247/18639	0.0283400809716599	1.15334229089688	0.405007198871895	0.656985627149672
GO:0008373	sialyltransferase activity	1/458	21/18639	0.0476190476190476	1.93792888334373	0.407108840555516	0.656985627149672
GO:0015174	basic amino acid transmembrane transporter activity	1/458	21/18639	0.0476190476190476	1.93792888334373	0.407108840555516	0.656985627149672
GO:0051428	peptide hormone receptor binding	1/458	21/18639	0.0476190476190476	1.93792888334373	0.407108840555516	0.656985627149672
GO:0061891	calcium ion sensor activity	1/458	21/18639	0.0476190476190476	1.93792888334373	0.407108840555516	0.656985627149672
GO:1904047	S-adenosyl-L-methionine binding	1/458	21/18639	0.0476190476190476	1.93792888334373	0.407108840555516	0.656985627149672
GO:0016410	N-acyltransferase activity	3/458	94/18639	0.0319148936170213	1.29882467713463	0.407761062665699	0.656985627149672
GO:0042562	hormone binding	3/458	94/18639	0.0319148936170213	1.29882467713463	0.407761062665699	0.656985627149672
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	4/458	132/18639	0.0303030303030303	1.23322747121874	0.407995063668746	0.656985627149672
GO:0004867	serine-type endopeptidase inhibitor activity	3/458	95/18639	0.0315789473684211	1.28515283842795	0.414353802684169	0.665799272689092
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	2/458	58/18639	0.0344827586206897	1.40332781207649	0.418855964863368	0.670430852392398
GO:0016407	acetyltransferase activity	3/458	96/18639	0.03125	1.27176582969432	0.420923082286788	0.670430852392398
GO:0016881	acid-amino acid ligase activity	1/458	22/18639	0.0454545454545455	1.84984120682811	0.421693873911708	0.670430852392398
GO:0061133	endopeptidase activator activity	1/458	22/18639	0.0454545454545455	1.84984120682811	0.421693873911708	0.670430852392398
GO:0140784	metal ion sensor activity	1/458	22/18639	0.0454545454545455	1.84984120682811	0.421693873911708	0.670430852392398
GO:0001786	phosphatidylserine binding	2/458	59/18639	0.0338983050847458	1.37954259492266	0.427352335601028	0.676566223940995
GO:0015459	potassium channel regulator activity	2/458	59/18639	0.0338983050847458	1.37954259492266	0.427352335601028	0.676566223940995
GO:0004714	transmembrane receptor protein tyrosine kinase activity	2/458	60/18639	0.0333333333333333	1.35655021834061	0.435783077937719	0.677298560143061
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	2/458	60/18639	0.0333333333333333	1.35655021834061	0.435783077937719	0.677298560143061
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/458	23/18639	0.0434782608695652	1.76941332827036	0.435920881794204	0.677298560143061
GO:0005158	insulin receptor binding	1/458	23/18639	0.0434782608695652	1.76941332827036	0.435920881794204	0.677298560143061
GO:0005283	amino acid:sodium symporter activity	1/458	23/18639	0.0434782608695652	1.76941332827036	0.435920881794204	0.677298560143061
GO:0008171	O-methyltransferase activity	1/458	23/18639	0.0434782608695652	1.76941332827036	0.435920881794204	0.677298560143061
GO:0016493	C-C chemokine receptor activity	1/458	23/18639	0.0434782608695652	1.76941332827036	0.435920881794204	0.677298560143061
GO:0017134	fibroblast growth factor binding	1/458	23/18639	0.0434782608695652	1.76941332827036	0.435920881794204	0.677298560143061
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/458	23/18639	0.0434782608695652	1.76941332827036	0.435920881794204	0.677298560143061
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	2/458	61/18639	0.0327868852459016	1.33431169017109	0.444146284256929	0.68610258176761
GO:0016836	hydro-lyase activity	2/458	61/18639	0.0327868852459016	1.33431169017109	0.444146284256929	0.68610258176761
GO:0001664	G protein-coupled receptor binding	8/458	297/18639	0.0269360269360269	1.09620219663888	0.446458400934783	0.68610258176761
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/458	24/18639	0.0416666666666667	1.69568777292576	0.449798634057755	0.68610258176761
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/458	24/18639	0.0416666666666667	1.69568777292576	0.449798634057755	0.68610258176761
GO:0019957	C-C chemokine binding	1/458	24/18639	0.0416666666666667	1.69568777292576	0.449798634057755	0.68610258176761
GO:0030552	cAMP binding	1/458	24/18639	0.0416666666666667	1.69568777292576	0.449798634057755	0.68610258176761
GO:0050431	transforming growth factor beta binding	1/458	24/18639	0.0416666666666667	1.69568777292576	0.449798634057755	0.68610258176761
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/458	24/18639	0.0416666666666667	1.69568777292576	0.449798634057755	0.68610258176761
GO:0004713	protein tyrosine kinase activity	4/458	140/18639	0.0285714285714286	1.16275733000624	0.451920916443535	0.687944391023356
GO:0000030	mannosyltransferase activity	1/458	25/18639	0.04	1.62786026200873	0.463335686198584	0.701063251551983
GO:0005537	D-mannose binding	1/458	25/18639	0.04	1.62786026200873	0.463335686198584	0.701063251551983
GO:0008483	transaminase activity	1/458	25/18639	0.04	1.62786026200873	0.463335686198584	0.701063251551983
GO:0005253	monoatomic anion channel activity	3/458	103/18639	0.029126213592233	1.18533514223937	0.466140095665592	0.703890264940814
GO:0019955	cytokine binding	4/458	144/18639	0.0277777777777778	1.13045851528384	0.473496110164879	0.704560673955461
GO:0001637	G protein-coupled chemoattractant receptor activity	1/458	26/18639	0.0384615384615385	1.56525025193147	0.476540384582653	0.704560673955461
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/458	26/18639	0.0384615384615385	1.56525025193147	0.476540384582653	0.704560673955461
GO:0004950	chemokine receptor activity	1/458	26/18639	0.0384615384615385	1.56525025193147	0.476540384582653	0.704560673955461
GO:0005160	transforming growth factor beta receptor binding	1/458	26/18639	0.0384615384615385	1.56525025193147	0.476540384582653	0.704560673955461
GO:0008198	ferrous iron binding	1/458	26/18639	0.0384615384615385	1.56525025193147	0.476540384582653	0.704560673955461
GO:0030507	spectrin binding	1/458	26/18639	0.0384615384615385	1.56525025193147	0.476540384582653	0.704560673955461
GO:0043548	phosphatidylinositol 3-kinase binding	1/458	26/18639	0.0384615384615385	1.56525025193147	0.476540384582653	0.704560673955461
GO:0070006	metalloaminopeptidase activity	1/458	26/18639	0.0384615384615385	1.56525025193147	0.476540384582653	0.704560673955461
GO:0070412	R-SMAD binding	1/458	26/18639	0.0384615384615385	1.56525025193147	0.476540384582653	0.704560673955461
GO:0038024	cargo receptor activity	2/458	65/18639	0.0307692307692308	1.25220020154518	0.476890137025704	0.704560673955461
GO:0000149	SNARE binding	3/458	106/18639	0.0283018867924528	1.15178792123259	0.485042151874674	0.713331129287677
GO:0031406	carboxylic acid binding	5/458	187/18639	0.0267379679144385	1.08814188636947	0.487760719754487	0.713331129287677
GO:0001671	ATPase activator activity	1/458	27/18639	0.037037037037037	1.50727802037846	0.489420871546664	0.713331129287677
GO:0005385	zinc ion transmembrane transporter activity	1/458	27/18639	0.037037037037037	1.50727802037846	0.489420871546664	0.713331129287677
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/458	27/18639	0.037037037037037	1.50727802037846	0.489420871546664	0.713331129287677
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	1/458	27/18639	0.037037037037037	1.50727802037846	0.489420871546664	0.713331129287677
GO:0015085	calcium ion transmembrane transporter activity	4/458	147/18639	0.0272108843537415	1.10738793333927	0.489466572755906	0.713331129287677
GO:0016500	protein-hormone receptor activity	2/458	67/18639	0.0298507462686567	1.21482109105129	0.492816523963357	0.716824034855792
GO:0043177	organic acid binding	5/458	189/18639	0.0264550264550265	1.07662715741318	0.497107694905118	0.720795212023232
GO:0005496	steroid binding	3/458	108/18639	0.0277777777777778	1.13045851528384	0.497463716808587	0.720795212023232
GO:0003777	microtubule motor activity	2/458	68/18639	0.0294117647058824	1.19695607500642	0.500664075567833	0.721783533388041
GO:1990841	promoter-specific chromatin binding	2/458	68/18639	0.0294117647058824	1.19695607500642	0.500664075567833	0.721783533388041
GO:0046625	sphingolipid binding	1/458	28/18639	0.0357142857142857	1.4534466625078	0.501985090374927	0.721783533388041
GO:0046875	ephrin receptor binding	1/458	28/18639	0.0357142857142857	1.4534466625078	0.501985090374927	0.721783533388041
GO:0008080	N-acetyltransferase activity	2/458	69/18639	0.0289855072463768	1.17960888551358	0.508433186786356	0.729112795338172
GO:0004222	metalloendopeptidase activity	3/458	110/18639	0.0272727272727273	1.10990472409686	0.509733022654554	0.729112795338172
GO:0004629	phospholipase C activity	1/458	29/18639	0.0344827586206897	1.40332781207649	0.514240790155073	0.729112795338172
GO:0005416	amino acid:monoatomic cation symporter activity	1/458	29/18639	0.0344827586206897	1.40332781207649	0.514240790155073	0.729112795338172
GO:0010484	histone H3 acetyltransferase activity	1/458	29/18639	0.0344827586206897	1.40332781207649	0.514240790155073	0.729112795338172
GO:0035250	UDP-galactosyltransferase activity	1/458	29/18639	0.0344827586206897	1.40332781207649	0.514240790155073	0.729112795338172
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	1/458	29/18639	0.0344827586206897	1.40332781207649	0.514240790155073	0.729112795338172
GO:0005125	cytokine activity	6/458	234/18639	0.0256410256410256	1.04350016795432	0.515687216311226	0.729112795338172
GO:1902936	phosphatidylinositol bisphosphate binding	3/458	111/18639	0.027027027027027	1.09990558243833	0.51580852010626	0.729112795338172
GO:0003774	cytoskeletal motor activity	4/458	153/18639	0.0261437908496732	1.06396095556126	0.520785319563483	0.734766529665552
GO:0140299	molecular sensor activity	2/458	71/18639	0.028169014084507	1.14638046620333	0.523732619873705	0.737541067687315
GO:0033612	receptor serine/threonine kinase binding	1/458	30/18639	0.0333333333333333	1.35655021834061	0.526195530515577	0.738244475648719
GO:0048019	receptor antagonist activity	1/458	30/18639	0.0333333333333333	1.35655021834061	0.526195530515577	0.738244475648719
GO:0005164	tumor necrosis factor receptor binding	1/458	31/18639	0.032258064516129	1.31279053387801	0.537856686247957	0.744685441400605
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/458	31/18639	0.032258064516129	1.31279053387801	0.537856686247957	0.744685441400605
GO:0008327	methyl-CpG binding	1/458	31/18639	0.032258064516129	1.31279053387801	0.537856686247957	0.744685441400605
GO:0047499	calcium-independent phospholipase A2 activity	1/458	31/18639	0.032258064516129	1.31279053387801	0.537856686247957	0.744685441400605
GO:0072349	modified amino acid transmembrane transporter activity	1/458	31/18639	0.032258064516129	1.31279053387801	0.537856686247957	0.744685441400605
GO:0001221	transcription coregulator binding	3/458	115/18639	0.0260869565217391	1.06164799696222	0.539698890376768	0.744685441400605
GO:0017124	SH3 domain binding	3/458	115/18639	0.0260869565217391	1.06164799696222	0.539698890376768	0.744685441400605
GO:0035401	histone H3Y41 kinase activity	3/458	115/18639	0.0260869565217391	1.06164799696222	0.539698890376768	0.744685441400605
GO:0140801	histone H2AXY142 kinase activity	3/458	115/18639	0.0260869565217391	1.06164799696222	0.539698890376768	0.744685441400605
GO:0003684	damaged DNA binding	2/458	74/18639	0.027027027027027	1.09990558243833	0.546074092823681	0.746875319649126
GO:0008378	galactosyltransferase activity	1/458	32/18639	0.03125	1.27176582969432	0.549231451816445	0.746875319649126
GO:0015106	bicarbonate transmembrane transporter activity	1/458	32/18639	0.03125	1.27176582969432	0.549231451816445	0.746875319649126
GO:0043425	bHLH transcription factor binding	1/458	32/18639	0.03125	1.27176582969432	0.549231451816445	0.746875319649126
GO:0047498	calcium-dependent phospholipase A2 activity	1/458	32/18639	0.03125	1.27176582969432	0.549231451816445	0.746875319649126
GO:0051059	NF-kappaB binding	1/458	32/18639	0.03125	1.27176582969432	0.549231451816445	0.746875319649126
GO:0071813	lipoprotein particle binding	1/458	32/18639	0.03125	1.27176582969432	0.549231451816445	0.746875319649126
GO:0071814	protein-lipid complex binding	1/458	32/18639	0.03125	1.27176582969432	0.549231451816445	0.746875319649126
GO:1990782	protein tyrosine kinase binding	3/458	117/18639	0.0256410256410256	1.04350016795432	0.551387879674941	0.748454305984758
GO:0099106	ion channel regulator activity	4/458	160/18639	0.025	1.01741266375546	0.556133231536098	0.753535477684947
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/458	33/18639	0.0303030303030303	1.23322747121874	0.560326845757869	0.756491540412778
GO:0140311	protein sequestering activity	1/458	33/18639	0.0303030303030303	1.23322747121874	0.560326845757869	0.756491540412778
GO:0033218	amide binding	6/458	247/18639	0.0242914979757085	0.988579106483037	0.5686242159016	0.762885587319278
GO:0008175	tRNA methyltransferase activity	1/458	34/18639	0.0294117647058824	1.19695607500642	0.571149714974406	0.762885587319278
GO:0015020	glucuronosyltransferase activity	1/458	34/18639	0.0294117647058824	1.19695607500642	0.571149714974406	0.762885587319278
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/458	34/18639	0.0294117647058824	1.19695607500642	0.571149714974406	0.762885587319278
GO:0030332	cyclin binding	1/458	34/18639	0.0294117647058824	1.19695607500642	0.571149714974406	0.762885587319278
GO:0051427	hormone receptor binding	1/458	34/18639	0.0294117647058824	1.19695607500642	0.571149714974406	0.762885587319278
GO:0015108	chloride transmembrane transporter activity	3/458	121/18639	0.0247933884297521	1.00900429463351	0.574230832462879	0.764919469987982
GO:0019199	transmembrane receptor protein kinase activity	2/458	78/18639	0.0256410256410256	1.04350016795432	0.574706782637247	0.764919469987982
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	3/458	122/18639	0.0245901639344262	1.00073376762832	0.5798273204972	0.766100643904049
GO:0000175	3'-5'-RNA exonuclease activity	1/458	35/18639	0.0285714285714286	1.16275733000624	0.581706738921825	0.766100643904049
GO:0004623	phospholipase A2 activity	1/458	35/18639	0.0285714285714286	1.16275733000624	0.581706738921825	0.766100643904049
GO:0005154	epidermal growth factor receptor binding	1/458	35/18639	0.0285714285714286	1.16275733000624	0.581706738921825	0.766100643904049
GO:0005343	organic acid:sodium symporter activity	1/458	35/18639	0.0285714285714286	1.16275733000624	0.581706738921825	0.766100643904049
GO:0010485	histone H4 acetyltransferase activity	1/458	35/18639	0.0285714285714286	1.16275733000624	0.581706738921825	0.766100643904049
GO:0005525	GTP binding	9/458	378/18639	0.0238095238095238	0.968964441671865	0.585385302495656	0.76959746062366
GO:0004190	aspartic-type endopeptidase activity	1/458	36/18639	0.0277777777777778	1.13045851528384	0.592004433695734	0.775587690137965
GO:0045505	dynein intermediate chain binding	1/458	36/18639	0.0277777777777778	1.13045851528384	0.592004433695734	0.775587690137965
GO:0016247	channel regulator activity	4/458	168/18639	0.0238095238095238	0.968964441671865	0.594760712774966	0.777202140888919
GO:0030971	receptor tyrosine kinase binding	2/458	81/18639	0.0246913580246914	1.00485201358564	0.595303767489384	0.777202140888919
GO:0030551	cyclic nucleotide binding	1/458	37/18639	0.027027027027027	1.09990558243833	0.602049156018335	0.783288867345654
GO:0070001	aspartic-type peptidase activity	1/458	37/18639	0.027027027027027	1.09990558243833	0.602049156018335	0.783288867345654
GO:0141108	transporter regulator activity	4/458	170/18639	0.0235294117647059	0.957564860005137	0.604101154717119	0.78460115431308
GO:0001540	amyloid-beta binding	2/458	83/18639	0.0240963855421687	0.980638712053454	0.608615479781992	0.785900539082073
GO:0005109	frizzled binding	1/458	38/18639	0.0263157894736842	1.07096069868996	0.611847107128087	0.785900539082073
GO:0005501	retinoid binding	1/458	38/18639	0.0263157894736842	1.07096069868996	0.611847107128087	0.785900539082073
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/458	38/18639	0.0263157894736842	1.07096069868996	0.611847107128087	0.785900539082073
GO:0019840	isoprenoid binding	1/458	38/18639	0.0263157894736842	1.07096069868996	0.611847107128087	0.785900539082073
GO:0042887	amide transmembrane transporter activity	1/458	38/18639	0.0263157894736842	1.07096069868996	0.611847107128087	0.785900539082073
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	3/458	128/18639	0.0234375	0.953824372270742	0.612417175401722	0.785900539082073
GO:0035591	signaling adaptor activity	3/458	129/18639	0.0232558139534884	0.946430384888799	0.617681185613622	0.791305368963278
GO:0003823	antigen binding	4/458	174/18639	0.0229885057471264	0.935551874717663	0.622385850633597	0.795976462034804
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	2/458	86/18639	0.0232558139534884	0.946430384888799	0.627954537071795	0.798495813018276
GO:0050660	flavin adenine dinucleotide binding	2/458	86/18639	0.0232558139534884	0.946430384888799	0.627954537071795	0.798495813018276
GO:0004177	aminopeptidase activity	1/458	40/18639	0.025	1.01741266375546	0.630726745921351	0.798495813018276
GO:0004532	RNA exonuclease activity	1/458	40/18639	0.025	1.01741266375546	0.630726745921351	0.798495813018276
GO:0050997	quaternary ammonium group binding	1/458	40/18639	0.025	1.01741266375546	0.630726745921351	0.798495813018276
GO:0071949	FAD binding	1/458	40/18639	0.025	1.01741266375546	0.630726745921351	0.798495813018276
GO:0008081	phosphoric diester hydrolase activity	2/458	87/18639	0.0229885057471264	0.935551874717663	0.634233891788096	0.801586364075039
GO:0042169	SH2 domain binding	1/458	41/18639	0.024390243902439	0.992597720737033	0.639820092357612	0.805937536772067
GO:0140828	metal cation:monoatomic cation antiporter activity	1/458	41/18639	0.024390243902439	0.992597720737033	0.639820092357612	0.805937536772067
GO:0004402	histone acetyltransferase activity	1/458	42/18639	0.0238095238095238	0.968964441671865	0.6486899922232	0.815743936708774
GO:0019001	guanyl nucleotide binding	9/458	400/18639	0.0225	0.915671397379913	0.652541841771792	0.817160792032689
GO:0032561	guanyl ribonucleotide binding	9/458	400/18639	0.0225	0.915671397379913	0.652541841771792	0.817160792032689
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	4/458	181/18639	0.0220994475138122	0.899370310502063	0.653076643632508	0.817160792032689
GO:0005096	GTPase activator activity	6/458	271/18639	0.022140221402214	0.901029665318487	0.658234633585225	0.822246585475231
GO:0001046	core promoter sequence-specific DNA binding	1/458	44/18639	0.0227272727272727	0.924920603414053	0.6657812339006	0.830294341448178
GO:0140767	enzyme-substrate adaptor activity	3/458	139/18639	0.0215827338129496	0.878341867990324	0.66762854929464	0.831219650777432
GO:0051213	dioxygenase activity	2/458	93/18639	0.021505376344086	0.875193689252007	0.670175616956293	0.832278944621561
GO:0005126	cytokine receptor binding	6/458	275/18639	0.0218181818181818	0.887923779277491	0.671995795622194	0.832278944621561
GO:0004715	non-membrane spanning protein tyrosine kinase activity	1/458	45/18639	0.0222222222222222	0.904366812227074	0.674013134673578	0.832278944621561
GO:0008009	chemokine activity	1/458	45/18639	0.0222222222222222	0.904366812227074	0.674013134673578	0.832278944621561
GO:0140303	intramembrane lipid transporter activity	1/458	45/18639	0.0222222222222222	0.904366812227074	0.674013134673578	0.832278944621561
GO:0008234	cysteine-type peptidase activity	4/458	187/18639	0.0213903743315508	0.870513509095579	0.678024400096424	0.835859588315591
GO:0004896	cytokine receptor activity	2/458	96/18639	0.0208333333333333	0.847843886462882	0.687048792146066	0.845598513410543
GO:0043495	protein-membrane adaptor activity	1/458	47/18639	0.0212765957446809	0.865883118089752	0.689874931697499	0.846306604627275
GO:0061733	protein-lysine-acetyltransferase activity	1/458	47/18639	0.0212765957446809	0.865883118089752	0.689874931697499	0.846306604627275
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/458	48/18639	0.0208333333333333	0.847843886462882	0.697514630561664	0.848215731274095
GO:0005004	GPI-linked ephrin receptor activity	1/458	49/18639	0.0204081632653061	0.830540950004456	0.704966531976476	0.848215731274095
GO:0005008	hepatocyte growth factor receptor activity	1/458	49/18639	0.0204081632653061	0.830540950004456	0.704966531976476	0.848215731274095
GO:0005009	insulin receptor activity	1/458	49/18639	0.0204081632653061	0.830540950004456	0.704966531976476	0.848215731274095
GO:0005011	macrophage colony-stimulating factor receptor activity	1/458	49/18639	0.0204081632653061	0.830540950004456	0.704966531976476	0.848215731274095
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/458	49/18639	0.0204081632653061	0.830540950004456	0.704966531976476	0.848215731274095
GO:0005020	stem cell factor receptor activity	1/458	49/18639	0.0204081632653061	0.830540950004456	0.704966531976476	0.848215731274095
GO:0008288	boss receptor activity	1/458	49/18639	0.0204081632653061	0.830540950004456	0.704966531976476	0.848215731274095
GO:0036332	placental growth factor receptor activity	1/458	49/18639	0.0204081632653061	0.830540950004456	0.704966531976476	0.848215731274095
GO:0038062	protein tyrosine kinase collagen receptor activity	1/458	49/18639	0.0204081632653061	0.830540950004456	0.704966531976476	0.848215731274095
GO:0060175	brain-derived neurotrophic factor receptor activity	1/458	49/18639	0.0204081632653061	0.830540950004456	0.704966531976476	0.848215731274095
GO:0060590	ATPase regulator activity	1/458	49/18639	0.0204081632653061	0.830540950004456	0.704966531976476	0.848215731274095
GO:0003924	GTPase activity	7/458	331/18639	0.0211480362537764	0.860651195926068	0.708028646736559	0.849304820599056
GO:0005006	epidermal growth factor receptor activity	1/458	50/18639	0.02	0.813930131004367	0.71223524248507	0.849304820599056
GO:0005017	platelet-derived growth factor receptor activity	1/458	50/18639	0.02	0.813930131004367	0.71223524248507	0.849304820599056
GO:0005019	platelet-derived growth factor beta-receptor activity	1/458	50/18639	0.02	0.813930131004367	0.71223524248507	0.849304820599056
GO:0032813	tumor necrosis factor receptor superfamily binding	1/458	50/18639	0.02	0.813930131004367	0.71223524248507	0.849304820599056
GO:0008509	monoatomic anion transmembrane transporter activity	3/458	149/18639	0.0201342281879195	0.819392749333255	0.712648060901602	0.849304820599056
GO:0008238	exopeptidase activity	2/458	102/18639	0.0196078431372549	0.797970716670948	0.718666572164653	0.850522944055776
GO:0005010	insulin-like growth factor receptor activity	1/458	51/18639	0.0196078431372549	0.797970716670948	0.71932525587696	0.850522944055776
GO:0005021	vascular endothelial growth factor receptor activity	1/458	51/18639	0.0196078431372549	0.797970716670948	0.71932525587696	0.850522944055776
GO:0005030	neurotrophin receptor activity	1/458	51/18639	0.0196078431372549	0.797970716670948	0.71932525587696	0.850522944055776
GO:0030544	Hsp70 protein binding	1/458	51/18639	0.0196078431372549	0.797970716670948	0.71932525587696	0.850522944055776
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	1/458	52/18639	0.0192307692307692	0.782625125965737	0.726240955941967	0.856008148696488
GO:0030159	signaling receptor complex adaptor activity	1/458	52/18639	0.0192307692307692	0.782625125965737	0.726240955941967	0.856008148696488
GO:0005003	ephrin receptor activity	1/458	53/18639	0.0188679245283019	0.767858614155063	0.732986619157041	0.857240960507146
GO:0005005	transmembrane-ephrin receptor activity	1/458	53/18639	0.0188679245283019	0.767858614155063	0.732986619157041	0.857240960507146
GO:0005544	calcium-dependent phospholipid binding	1/458	53/18639	0.0188679245283019	0.767858614155063	0.732986619157041	0.857240960507146
GO:0034212	protein N-acetyltransferase activity	1/458	53/18639	0.0188679245283019	0.767858614155063	0.732986619157041	0.857240960507146
GO:0038064	collagen receptor activity	1/458	53/18639	0.0188679245283019	0.767858614155063	0.732986619157041	0.857240960507146
GO:0050661	NADP binding	1/458	54/18639	0.0185185185185185	0.753639010189228	0.739566417307588	0.86359308356414
GO:0004620	phospholipase activity	2/458	109/18639	0.018348623853211	0.746724890829694	0.752114848143552	0.876884288068141
GO:0008408	3'-5' exonuclease activity	1/458	58/18639	0.0172413793103448	0.701663906038247	0.764306872251693	0.889719455005067
GO:0004879	nuclear receptor activity	1/458	59/18639	0.0169491525423729	0.689771297461328	0.770116433228429	0.895096689007386
GO:0015103	inorganic anion transmembrane transporter activity	3/458	165/18639	0.0181818181818182	0.739936482731243	0.774687883618694	0.896142690324079
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/458	60/18639	0.0166666666666667	0.678275109170306	0.775783100267255	0.896142690324079
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/458	60/18639	0.0166666666666667	0.678275109170306	0.775783100267255	0.896142690324079
GO:0098531	ligand-modulated transcription factor activity	1/458	60/18639	0.0166666666666667	0.678275109170306	0.775783100267255	0.896142690324079
GO:0015026	coreceptor activity	1/458	61/18639	0.0163934426229508	0.667155845085547	0.781310380534093	0.899763255990258
GO:0019905	syntaxin binding	1/458	61/18639	0.0163934426229508	0.667155845085547	0.781310380534093	0.899763255990258
GO:0008235	metalloexopeptidase activity	1/458	66/18639	0.0151515151515152	0.616613735609369	0.80697283456428	0.927895369407245
GO:0008173	RNA methyltransferase activity	1/458	67/18639	0.0149253731343284	0.607410545525647	0.811732778664294	0.931943587107709
GO:0005548	phospholipid transporter activity	1/458	68/18639	0.0147058823529412	0.598478037503211	0.81637559512842	0.934270278556022
GO:0140223	general transcription initiation factor activity	1/458	68/18639	0.0147058823529412	0.598478037503211	0.81637559512842	0.934270278556022
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	4/458	229/18639	0.0174672489082969	0.710856009610801	0.817486493736519	0.934270278556022
GO:0002039	p53 binding	1/458	69/18639	0.0144927536231884	0.589804442756788	0.82090415995698	0.936752546718739
GO:0016298	lipase activity	2/458	130/18639	0.0153846153846154	0.62610010077259	0.832614687268095	0.947192911711579
GO:0008237	metallopeptidase activity	3/458	184/18639	0.016304347826087	0.663529998101386	0.833647877306334	0.947192911711579
GO:0042379	chemokine receptor binding	1/458	72/18639	0.0138888888888889	0.565229257641921	0.83383205791631	0.947192911711579
GO:0005262	calcium channel activity	2/458	131/18639	0.0152671755725191	0.621320710690356	0.835786024868253	0.947980528960673
GO:0140098	catalytic activity, acting on RNA	7/458	387/18639	0.0180878552971576	0.736112521580177	0.841860737611126	0.953432642595733
GO:0019003	GDP binding	1/458	75/18639	0.0133333333333333	0.542620087336245	0.845828655292545	0.956485938015028
GO:0015297	antiporter activity	2/458	135/18639	0.0148148148148148	0.602911208151383	0.84793542476098	0.957428587718104
GO:0017022	myosin binding	1/458	76/18639	0.0131578947368421	0.535480349344978	0.849632279289314	0.957713361405962
GO:0030695	GTPase regulator activity	9/458	489/18639	0.0184049079754601	0.749015457979479	0.852691281248474	0.957713361405962
GO:0060589	nucleoside-triphosphatase regulator activity	9/458	490/18639	0.0183673469387755	0.74748685500401	0.854278193240075	0.957713361405962
GO:0070851	growth factor receptor binding	2/458	139/18639	0.0143884892086331	0.585561245326883	0.859262779401509	0.957713361405962
GO:0140101	catalytic activity, acting on a tRNA	2/458	139/18639	0.0143884892086331	0.585561245326883	0.859262779401509	0.957713361405962
GO:0015370	solute:sodium symporter activity	1/458	79/18639	0.0126582278481013	0.515145652534409	0.860490451092013	0.957713361405962
GO:0046873	metal ion transmembrane transporter activity	8/458	450/18639	0.0177777777777778	0.723493449781659	0.866754937769393	0.957713361405962
GO:0033192	calmodulin-dependent protein phosphatase activity	1/458	81/18639	0.0123456790123457	0.502426006792819	0.867290956273218	0.957713361405962
GO:0140791	histone H2AXS140 phosphatase activity	1/458	81/18639	0.0123456790123457	0.502426006792819	0.867290956273218	0.957713361405962
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	1/458	81/18639	0.0123456790123457	0.502426006792819	0.867290956273218	0.957713361405962
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	1/458	81/18639	0.0123456790123457	0.502426006792819	0.867290956273218	0.957713361405962
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	1/458	81/18639	0.0123456790123457	0.502426006792819	0.867290956273218	0.957713361405962
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	1/458	81/18639	0.0123456790123457	0.502426006792819	0.867290956273218	0.957713361405962
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	1/458	81/18639	0.0123456790123457	0.502426006792819	0.867290956273218	0.957713361405962
GO:1990439	MAP kinase serine/threonine phosphatase activity	1/458	81/18639	0.0123456790123457	0.502426006792819	0.867290956273218	0.957713361405962
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	1/458	82/18639	0.0121951219512195	0.496298860368516	0.87056613366447	0.95851498172135
GO:0033549	MAP kinase phosphatase activity	1/458	82/18639	0.0121951219512195	0.496298860368516	0.87056613366447	0.95851498172135
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	1/458	83/18639	0.0120481927710843	0.490319356026727	0.873760653833769	0.960625748074553
GO:0004527	exonuclease activity	1/458	84/18639	0.0119047619047619	0.484482220835933	0.876876498872793	0.961240710134607
GO:0017018	myosin phosphatase activity	1/458	84/18639	0.0119047619047619	0.484482220835933	0.876876498872793	0.961240710134607
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	1/458	91/18639	0.010989010989011	0.447214357694707	0.896641092998866	0.981476130909967
GO:0052689	carboxylic ester hydrolase activity	1/458	92/18639	0.0108695652173913	0.442353332067591	0.8991933023695	0.981509897808976
GO:0140375	immune receptor activity	2/458	156/18639	0.0128205128205128	0.521750083977158	0.899282339880831	0.981509897808976
GO:0008276	protein methyltransferase activity	1/458	95/18639	0.0105263157894737	0.428384279475983	0.906478757236546	0.987930471654903
GO:0030527	structural constituent of chromatin	1/458	98/18639	0.0102040816326531	0.415270475002228	0.913238747359678	0.993463828224998
GO:0015081	sodium ion transmembrane transporter activity	2/458	164/18639	0.0121951219512195	0.496298860368516	0.914198097249599	0.993463828224998
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	2/458	167/18639	0.0119760479041916	0.487383311978663	0.919237763357889	0.997498987078113
GO:0004722	protein serine/threonine phosphatase activity	1/458	103/18639	0.00970873786407767	0.39511171407979	0.923439189566019	0.99974108623061
GO:0004497	monooxygenase activity	1/458	106/18639	0.00943396226415094	0.383929307077532	0.928975558895306	0.99974108623061
GO:0008013	beta-catenin binding	1/458	106/18639	0.00943396226415094	0.383929307077532	0.928975558895306	0.99974108623061
GO:0141003	histone H2AX kinase activity	5/458	354/18639	0.0141242937853107	0.574809414551106	0.938019148475815	0.99974108623061
GO:0140996	histone H3 kinase activity	5/458	357/18639	0.0140056022408964	0.569979083336391	0.940809661377998	0.99974108623061
GO:0035173	histone kinase activity	5/458	360/18639	0.0138888888888889	0.565229257641921	0.943486825283838	0.99974108623061
GO:0035402	histone H3T11 kinase activity	3/458	247/18639	0.0121457489878543	0.494289553241518	0.94430914703047	0.99974108623061
GO:0004540	RNA nuclease activity	1/458	121/18639	0.00826446280991736	0.336334764877838	0.951209625859614	0.99974108623061
GO:0008528	G protein-coupled peptide receptor activity	1/458	122/18639	0.00819672131147541	0.333577922542773	0.952416343180939	0.99974108623061
GO:0004674	protein serine/threonine kinase activity	6/458	433/18639	0.0138568129330254	0.563923878294019	0.957186938244884	0.99974108623061
GO:0001653	peptide receptor activity	1/458	128/18639	0.0078125	0.317941457423581	0.959056278060296	0.99974108623061
GO:0016798	hydrolase activity, acting on glycosyl bonds	1/458	130/18639	0.00769230769230769	0.313050050386295	0.961057329809306	0.99974108623061
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1/458	130/18639	0.00769230769230769	0.313050050386295	0.961057329809306	0.99974108623061
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	3/458	268/18639	0.0111940298507463	0.455557909144235	0.962238137992621	0.99974108623061
GO:0008168	methyltransferase activity	2/458	204/18639	0.00980392156862745	0.398985358335474	0.962351196060957	0.99974108623061
GO:0005216	monoatomic ion channel activity	6/458	448/18639	0.0133928571428571	0.545042498440424	0.965872364302024	0.99974108623061
GO:0140789	histone phosphatase activity	1/458	136/18639	0.00735294117647059	0.299239018751605	0.966493685592612	0.99974108623061
GO:0001217	DNA-binding transcription repressor activity	3/458	278/18639	0.0107913669064748	0.439170933995162	0.968722975428421	0.99974108623061
GO:0016741	transferase activity, transferring one-carbon groups	2/458	215/18639	0.00930232558139535	0.378572153955519	0.970148535440145	0.99974108623061
GO:0005085	guanyl-nucleotide exchange factor activity	2/458	230/18639	0.00869565217391304	0.353882665654073	0.978316909238411	0.99974108623061
GO:0042578	phosphoric ester hydrolase activity	4/458	363/18639	0.0110192837465565	0.44844635317045	0.979555312184431	0.99974108623061
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	2/458	243/18639	0.00823045267489712	0.334950671195213	0.983609688971022	0.99974108623061
GO:0004676	3-phosphoinositide-dependent protein kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:0004711	ribosomal protein S6 kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:0035175	histone H3S10 kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:0035979	histone H2AXS139 kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:0044022	histone H3S28 kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:0044023	histone H4S1 kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:0044024	histone H2AS1 kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:0044025	histone H2BS14 kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:0072354	histone H3T3 kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:0072371	histone H2AS121 kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:0072518	Rho-dependent protein serine/threonine kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:0140823	histone H2BS36 kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:0140855	histone H3S57 kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:0140995	histone H2A kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:0140997	histone H4 kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:0140998	histone H2B kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:1990244	histone H2AT120 kinase activity	2/458	245/18639	0.00816326530612245	0.332216380001782	0.984303710973697	0.99974108623061
GO:0016874	ligase activity	1/458	167/18639	0.00598802395209581	0.243691655989331	0.984604060347429	0.99974108623061
GO:0004677	DNA-dependent protein kinase activity	2/458	246/18639	0.00813008130081301	0.330865906912344	0.984639939382766	0.99974108623061
GO:0140857	histone H3T45 kinase activity	2/458	246/18639	0.00813008130081301	0.330865906912344	0.984639939382766	0.99974108623061
GO:0035403	histone H3T6 kinase activity	2/458	247/18639	0.00809716599190283	0.329526368827679	0.984969170340743	0.99974108623061
GO:0004679	AMP-activated protein kinase activity	2/458	248/18639	0.00806451612903226	0.328197633469503	0.98529154370301	0.99974108623061
GO:0004721	phosphoprotein phosphatase activity	1/458	175/18639	0.00571428571428571	0.232551466001248	0.987406125351716	0.99974108623061
GO:0005261	monoatomic cation channel activity	3/458	341/18639	0.00879765395894428	0.35803378196673	0.990855254648352	0.99974108623061
GO:0016791	phosphatase activity	2/458	273/18639	0.00732600732600733	0.298142905129805	0.991481568635143	0.99974108623061
GO:0061630	ubiquitin protein ligase activity	3/458	353/18639	0.0084985835694051	0.345862661899873	0.992817033278592	0.99974108623061
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	5/458	484/18639	0.0103305785123967	0.420418456097297	0.992902044106998	0.99974108623061
GO:0001216	DNA-binding transcription activator activity	5/458	491/18639	0.010183299389002	0.414424710287356	0.993736775669941	0.99974108623061
GO:0106310	protein serine kinase activity	3/458	361/18639	0.00831024930747922	0.338198115375776	0.993891944810815	0.99974108623061
GO:0004518	nuclease activity	1/458	209/18639	0.00478468899521531	0.194720127034538	0.994642862849717	0.99974108623061
GO:0061659	ubiquitin-like protein ligase activity	3/458	372/18639	0.00806451612903226	0.328197633469503	0.995119197949349	0.99974108623061
GO:0004842	ubiquitin-protein transferase activity	4/458	449/18639	0.0089086859688196	0.362552396883905	0.995879587950798	0.99974108623061
GO:0019787	ubiquitin-like protein transferase activity	4/458	479/18639	0.00835073068893528	0.339845566181364	0.997702115529639	0.99974108623061
GO:0016755	aminoacyltransferase activity	4/458	496/18639	0.00806451612903226	0.328197633469503	0.998357629034681	0.99974108623061
GO:0045182	translation regulator activity	2/458	356/18639	0.00561797752808989	0.22863205927089	0.998674975210759	0.99974108623061
GO:0022836	gated channel activity	1/458	318/18639	0.00314465408805031	0.127976435692511	0.99965791728561	0.99974108623061
GO:0030371	translation repressor activity	1/458	329/18639	0.00303951367781155	0.123697588298536	0.99974108623061	0.99974108623061