ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 115/1563 175/18639 0.657142857142857 7.83652316972854 1.12690041407724e-80 1.28466647204805e-77 GO:0003697 single-stranded DNA binding 46/1563 121/18639 0.380165289256198 4.53352580066941 1.89524492127334e-19 1.0802896051258e-16 GO:0045296 cadherin binding 79/1563 334/18639 0.236526946107784 2.82061788131989 1.17112333932444e-17 4.45026868943286e-15 GO:0016887 ATP hydrolysis activity 90/1563 417/18639 0.215827338129496 2.57377207638879 3.27419578033496e-17 9.33145797395465e-15 GO:0140097 catalytic activity, acting on DNA 71/1563 336/18639 0.211309523809524 2.51989649026597 2.30183915334422e-13 5.24819326962483e-11 GO:0048027 mRNA 5'-UTR binding 16/1563 24/18639 0.666666666666667 7.95009596928983 2.13749674224101e-12 4.06124381025793e-10 GO:0003678 DNA helicase activity 28/1563 74/18639 0.378378378378378 4.51221663121855 2.52090076861578e-12 4.10546696603141e-10 GO:0051082 unfolded protein binding 36/1563 121/18639 0.297520661157025 3.54797671356736 8.00894244511488e-12 1.11627538428745e-09 GO:0008094 ATP-dependent activity, acting on DNA 50/1563 210/18639 0.238095238095238 2.83931998903208 8.81270040226933e-12 1.11627538428745e-09 GO:0140104 molecular carrier activity 54/1563 249/18639 0.216867469879518 2.58617579723886 6.1586653776954e-11 7.02087853057276e-09 GO:0017116 single-stranded DNA helicase activity 23/1563 58/18639 0.396551724137931 4.72893639552585 7.37890127325035e-11 7.647224955914e-09 GO:0019843 rRNA binding 24/1563 65/18639 0.369230769230769 4.40313007529898 1.6749158102656e-10 1.59117001975232e-08 GO:0003684 damaged DNA binding 25/1563 74/18639 0.337837837837838 4.02876484930228 6.29125299158067e-10 5.51694493107844e-08 GO:0004386 helicase activity 38/1563 155/18639 0.245161290322581 2.92358367902916 1.12368603681896e-09 9.15001487124014e-08 GO:0003743 translation initiation factor activity 20/1563 51/18639 0.392156862745098 4.67652704075872 1.61254714012741e-09 1.22553582649683e-07 GO:0031625 ubiquitin protein ligase binding 58/1563 302/18639 0.19205298013245 2.29025943486164 1.77350495553798e-09 1.23501251878124e-07 GO:0008135 translation factor activity, RNA binding 26/1563 83/18639 0.313253012048193 3.73558726267835 1.84168533502465e-09 1.23501251878124e-07 GO:0180051 translation factor activity 26/1563 84/18639 0.30952380952381 3.69111598574171 2.45626346282937e-09 1.5556335264586e-07 GO:0044389 ubiquitin-like protein ligase binding 60/1563 322/18639 0.186335403726708 2.22207651315554 3.12044965098279e-09 1.87226979058967e-07 GO:0043021 ribonucleoprotein complex binding 39/1563 177/18639 0.220338983050847 2.62757409154494 1.72943376972529e-08 9.85777248743416e-07 GO:0000217 DNA secondary structure binding 16/1563 39/18639 0.41025641025641 4.8923667503322 3.24843533005529e-08 1.70152274207001e-06 GO:0055105 ubiquitin-protein transferase inhibitor activity 10/1563 15/18639 0.666666666666667 7.95009596928983 3.3925794205639e-08 1.70152274207001e-06 GO:0003689 DNA clamp loader activity 36/1563 160/18639 0.225 2.68315738963532 3.43289676031669e-08 1.70152274207001e-06 GO:0003688 DNA replication origin binding 10/1563 16/18639 0.625 7.45321497120921 8.36348131457226e-08 3.97265362442182e-06 GO:0031720 haptoglobin binding 8/1563 10/18639 0.8 9.54011516314779 9.27771320301269e-08 4.23063722057379e-06 GO:1990948 ubiquitin ligase inhibitor activity 8/1563 11/18639 0.727272727272727 8.67283196649799 3.14993339074838e-07 1.38112464055891e-05 GO:0008017 microtubule binding 49/1563 276/18639 0.177536231884058 2.11714512225653 3.94469530478272e-07 1.66553801757493e-05 GO:0055106 ubiquitin-protein transferase regulator activity 14/1563 36/18639 0.388888888888889 4.63755598208573 5.20684962302384e-07 2.11993163223113e-05 GO:0044183 protein folding chaperone 21/1563 75/18639 0.28 3.33904030710173 5.49669961253428e-07 2.16077157182382e-05 GO:0030515 snoRNA binding 13/1563 32/18639 0.40625 4.84458973128599 7.34118407617994e-07 2.78667681516178e-05 GO:0016853 isomerase activity 36/1563 180/18639 0.2 2.38502879078695 7.57780537456273e-07 2.78667681516178e-05 GO:0015631 tubulin binding 61/1563 385/18639 0.158441558441558 1.88943839270135 9.68256621014778e-07 3.44941421236515e-05 GO:0140658 ATP-dependent chromatin remodeler activity 32/1563 158/18639 0.20253164556962 2.41521902864501 2.30651432855741e-06 7.74746729049684e-05 GO:0140662 ATP-dependent protein folding chaperone 14/1563 40/18639 0.35 4.17380038387716 2.31064813927099e-06 7.74746729049684e-05 GO:0004601 peroxidase activity 17/1563 57/18639 0.298245614035088 3.55662188099808 2.50585283681764e-06 8.16192066849175e-05 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 17/1563 59/18639 0.288135593220339 3.43605842740493 4.23706106018802e-06 0.000134173600239287 GO:0005344 oxygen carrier activity 8/1563 14/18639 0.571428571428571 6.81436797367699 4.55350837906168e-06 0.000140297285192711 GO:0140713 histone chaperone activity 32/1563 164/18639 0.195121951219512 2.32685735686532 5.29206362611722e-06 0.000158761908783517 GO:0042393 histone binding 42/1563 247/18639 0.17004048582996 2.02775727151927 8.00629938639525e-06 0.000231479321614448 GO:0015616 DNA translocase activity 30/1563 152/18639 0.197368421052632 2.35364683301344 8.12208146015609e-06 0.000231479321614448 GO:0140597 protein carrier chaperone 34/1563 188/18639 0.180851063829787 2.15667497039245 1.51624345239105e-05 0.000421589642859952 GO:0061749 forked DNA-dependent helicase activity 14/1563 47/18639 0.297872340425532 3.55217053946992 1.94480280482979e-05 0.000466970247705811 GO:1990518 single-stranded 3'-5' DNA helicase activity 14/1563 47/18639 0.297872340425532 3.55217053946992 1.94480280482979e-05 0.000466970247705811 GO:0016860 intramolecular oxidoreductase activity 15/1563 53/18639 0.283018867924528 3.37504074167964 1.95680627259608e-05 0.000466970247705811 GO:0000510 H3-H4 histone complex chaperone activity 29/1563 151/18639 0.19205298013245 2.29025943486164 1.96619051665605e-05 0.000466970247705811 GO:0140584 chromatin extrusion motor activity 29/1563 151/18639 0.19205298013245 2.29025943486164 1.96619051665605e-05 0.000466970247705811 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 29/1563 151/18639 0.19205298013245 2.29025943486164 1.96619051665605e-05 0.000466970247705811 GO:0140849 ATP-dependent H2AZ histone chaperone activity 29/1563 151/18639 0.19205298013245 2.29025943486164 1.96619051665605e-05 0.000466970247705811 GO:0140674 ATP-dependent histone chaperone activity 29/1563 152/18639 0.190789473684211 2.27519193857965 2.23826766095339e-05 0.000520739823160584 GO:0017069 snRNA binding 15/1563 54/18639 0.277777777777778 3.31253998720409 2.50106210647664e-05 0.000537089365236205 GO:0009378 four-way junction helicase activity 14/1563 48/18639 0.291666666666667 3.4781669865643 2.53522352688519e-05 0.000537089365236205 GO:0036121 double-stranded DNA helicase activity 14/1563 48/18639 0.291666666666667 3.4781669865643 2.53522352688519e-05 0.000537089365236205 GO:0043138 3'-5' DNA helicase activity 14/1563 48/18639 0.291666666666667 3.4781669865643 2.53522352688519e-05 0.000537089365236205 GO:0061775 cohesin loader activity 29/1563 153/18639 0.189542483660131 2.26032140303338 2.54410751953992e-05 0.000537089365236205 GO:0031491 nucleosome binding 18/1563 74/18639 0.243243243243243 2.90071069149764 2.93583125902218e-05 0.000608517751870052 GO:0140517 protein-RNA adaptor activity 9/1563 22/18639 0.409090909090909 4.87846798115512 3.63909438986512e-05 0.000740815643651114 GO:0003713 transcription coactivator activity 41/1563 256/18639 0.16015625 1.90988633637236 4.3398982817158e-05 0.000867979656343161 GO:0098641 cadherin binding involved in cell-cell adhesion 8/1563 18/18639 0.444444444444444 5.30006397952655 4.88628221870503e-05 0.000960407194710989 GO:0070990 snRNP binding 6/1563 11/18639 0.545454545454545 6.50462397487349 0.000109947900279811 0.00212441705625397 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 13/1563 48/18639 0.270833333333333 3.22972648752399 0.000114379626489657 0.00217321290330348 GO:0043022 ribosome binding 22/1563 112/18639 0.196428571428571 2.34243899095147 0.000134935669699259 0.00252174858126484 GO:0070182 DNA polymerase binding 8/1563 21/18639 0.380952380952381 4.54291198245133 0.000180801999709145 0.00332442386561976 GO:0009055 electron transfer activity 22/1563 116/18639 0.189655172413793 2.2616652326428 0.000229079673405542 0.00414525123305267 GO:0015035 protein-disulfide reductase activity 10/1563 34/18639 0.294117647058824 3.50739528056904 0.000336483046327116 0.00599360426270176 GO:0003727 single-stranded RNA binding 18/1563 89/18639 0.202247191011236 2.41182686708793 0.000366319094707048 0.00629626727260039 GO:0019887 protein kinase regulator activity 38/1563 255/18639 0.149019607843137 1.77708027548831 0.000366980262269659 0.00629626727260039 GO:0005200 structural constituent of cytoskeleton 21/1563 112/18639 0.1875 2.23596449136276 0.000370043778301953 0.00629626727260039 GO:0000400 four-way junction DNA binding 7/1563 18/18639 0.388888888888889 4.63755598208573 0.000399963827792011 0.00655658958546109 GO:0070628 proteasome binding 7/1563 18/18639 0.388888888888889 4.63755598208573 0.000399963827792011 0.00655658958546109 GO:0000287 magnesium ion binding 35/1563 230/18639 0.152173913043478 1.81469581907703 0.000413694791443265 0.00655658958546109 GO:0008137 NADH dehydrogenase (ubiquinone) activity 11/1563 41/18639 0.268292682926829 3.19942886568981 0.00041557767650702 0.00655658958546109 GO:0003777 microtubule motor activity 15/1563 68/18639 0.220588235294118 2.63054646042678 0.000419851789244438 0.00655658958546109 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 15/1563 68/18639 0.220588235294118 2.63054646042678 0.000419851789244438 0.00655658958546109 GO:0098632 cell-cell adhesion mediator activity 13/1563 55/18639 0.236363636363636 2.81867038911185 0.000495159858887181 0.00762813836664035 GO:0003712 transcription coregulator activity 63/1563 495/18639 0.127272727272727 1.51774559413715 0.00056314455584574 0.00848522073485581 GO:0032036 myosin heavy chain binding 6/1563 14/18639 0.428571428571429 5.11077598025775 0.000573124558406928 0.00848522073485581 GO:1990825 sequence-specific mRNA binding 6/1563 14/18639 0.428571428571429 5.11077598025775 0.000573124558406928 0.00848522073485581 GO:0008301 DNA binding, bending 7/1563 19/18639 0.368421052631579 4.39347408829175 0.000587658592773039 0.00858885635591364 GO:0051015 actin filament binding 32/1563 209/18639 0.15311004784689 1.825859361368 0.000642356799090117 0.00926945254383208 GO:0016209 antioxidant activity 17/1563 86/18639 0.197674418604651 2.35729589787082 0.000694992318959465 0.00990364054517238 GO:0032356 oxidized DNA binding 5/1563 10/18639 0.5 5.96257197696737 0.000725100085894581 0.0100806597307295 GO:0050815 phosphoserine residue binding 5/1563 10/18639 0.5 5.96257197696737 0.000725100085894581 0.0100806597307295 GO:0003954 NADH dehydrogenase activity 11/1563 44/18639 0.25 2.98128598848369 0.000798754681302993 0.0109708474299447 GO:0140142 nucleocytoplasmic carrier activity 9/1563 32/18639 0.28125 3.35394673704415 0.000951876936943454 0.0129183298585183 GO:0034511 U3 snoRNA binding 5/1563 11/18639 0.454545454545455 5.42051997906125 0.00123772690724022 0.0164166775897938 GO:0003725 double-stranded RNA binding 15/1563 75/18639 0.2 2.38502879078695 0.00123845111642304 0.0164166775897938 GO:0017070 U6 snRNA binding 6/1563 16/18639 0.375 4.47192898272553 0.00132009382831551 0.017297781198617 GO:0015036 disulfide oxidoreductase activity 10/1563 40/18639 0.25 2.98128598848369 0.00136884112100144 0.0177327145220641 GO:0051117 ATPase binding 16/1563 84/18639 0.19047619047619 2.27145599122567 0.00149007544224774 0.0190863595973306 GO:0019825 oxygen binding 9/1563 34/18639 0.264705882352941 3.15665575251214 0.00152798919776795 0.019354529838394 GO:0061650 ubiquitin-like protein conjugating enzyme activity 10/1563 41/18639 0.24390243902439 2.90857169608164 0.00167634545793512 0.0210003716708356 GO:0019207 kinase regulator activity 39/1563 287/18639 0.13588850174216 1.62048994495977 0.00185979600659099 0.0230452983425405 GO:0004550 nucleoside diphosphate kinase activity 6/1563 17/18639 0.352941176470588 4.20887433668285 0.00189645889039604 0.0232469154306611 GO:0005049 nuclear export signal receptor activity 5/1563 12/18639 0.416666666666667 4.96880998080614 0.00197590858646406 0.0234639144642607 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 5/1563 12/18639 0.416666666666667 4.96880998080614 0.00197590858646406 0.0234639144642607 GO:1990247 N6-methyladenosine-containing RNA reader activity 5/1563 12/18639 0.416666666666667 4.96880998080614 0.00197590858646406 0.0234639144642607 GO:0008307 structural constituent of muscle 10/1563 42/18639 0.238095238095238 2.83931998903208 0.0020374358109711 0.0239451219021346 GO:0043539 protein serine/threonine kinase activator activity 14/1563 73/18639 0.191780821917808 2.28701390897379 0.00268601074648652 0.0312454311325983 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 12/1563 58/18639 0.206896551724138 2.46727116288305 0.00274203868611363 0.0315749909310054 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 5/1563 13/18639 0.384615384615385 4.58659382843644 0.00299056658957822 0.0340924591211917 GO:0036002 pre-mRNA binding 12/1563 59/18639 0.203389830508475 2.42545300757995 0.00318470621280849 0.0359461889366502 GO:0003779 actin binding 54/1563 443/18639 0.121896162528217 1.45362928558121 0.00344793508952172 0.0385357451181839 GO:0042162 telomeric DNA binding 9/1563 38/18639 0.236842105263158 2.82437619961612 0.00350289302848142 0.0386536693174254 GO:0003756 protein disulfide isomerase activity 6/1563 19/18639 0.315789473684211 3.7658349328215 0.00359411311197113 0.0386536693174254 GO:0008574 plus-end-directed microtubule motor activity 6/1563 19/18639 0.315789473684211 3.7658349328215 0.00359411311197113 0.0386536693174254 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 6/1563 19/18639 0.315789473684211 3.7658349328215 0.00359411311197113 0.0386536693174254 GO:0051087 protein-folding chaperone binding 21/1563 134/18639 0.156716417910448 1.86886584352709 0.0038536325175984 0.0410573931781512 GO:0098631 cell adhesion mediator activity 14/1563 76/18639 0.184210526315789 2.19673704414587 0.00394531955186431 0.0416450397141233 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 5/1563 14/18639 0.357142857142857 4.25897998354812 0.00433358994022893 0.0453237846959723 GO:0003774 cytoskeletal motor activity 23/1563 153/18639 0.150326797385621 1.79266869895751 0.00438059094098042 0.0453988515701608 GO:0140463 chromatin-protein adaptor activity 11/1563 54/18639 0.203703703703704 2.42919599061634 0.00459823456079356 0.0472251117054474 GO:0043024 ribosomal small subunit binding 6/1563 20/18639 0.3 3.57754318618042 0.00477485118457533 0.0486011638429989 GO:0016829 lyase activity 28/1563 200/18639 0.14 1.66952015355086 0.00503243420950834 0.0507696902552169 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 5/1563 15/18639 0.333333333333333 3.97504798464491 0.00605653927369353 0.0605653927369353 GO:0001094 TFIID-class transcription factor complex binding 4/1563 10/18639 0.4 4.7700575815739 0.00685064534237178 0.067325307675033 GO:0047429 nucleoside triphosphate diphosphatase activity 4/1563 10/18639 0.4 4.7700575815739 0.00685064534237178 0.067325307675033 GO:0031492 nucleosomal DNA binding 9/1563 42/18639 0.214285714285714 2.55538799012887 0.0070779140887313 0.0684255675655213 GO:0097718 disordered domain specific binding 7/1563 28/18639 0.25 2.98128598848369 0.00708264646730834 0.0684255675655213 GO:0140566 histone reader activity 8/1563 35/18639 0.228571428571429 2.7257471894708 0.0072785763159497 0.069727537816661 GO:0070034 telomerase RNA binding 6/1563 22/18639 0.272727272727273 3.25231198743675 0.00795266603045149 0.0755503272892892 GO:0048029 monosaccharide binding 13/1563 74/18639 0.175675675675676 2.09495772163718 0.0080767294212702 0.0760948061177523 GO:0022853 active monoatomic ion transmembrane transporter activity 18/1563 118/18639 0.152542372881356 1.81908975568496 0.00938544474556539 0.0877000574585618 GO:0044325 transmembrane transporter binding 20/1563 136/18639 0.147058823529412 1.75369764028452 0.00956985900286232 0.0885392156907358 GO:0019205 nucleobase-containing compound kinase activity 9/1563 44/18639 0.204545454545455 2.43923399057756 0.00967736835080374 0.0885392156907358 GO:0004527 exonuclease activity 14/1563 84/18639 0.166666666666667 1.98752399232246 0.00974738380012064 0.0885392156907358 GO:0017134 fibroblast growth factor binding 6/1563 23/18639 0.260869565217391 3.11090711841776 0.0100103550785619 0.0885392156907358 GO:0004523 RNA-DNA hybrid ribonuclease activity 4/1563 11/18639 0.363636363636364 4.336415983249 0.0100580273053041 0.0885392156907358 GO:0010854 adenylate cyclase regulator activity 4/1563 11/18639 0.363636363636364 4.336415983249 0.0100580273053041 0.0885392156907358 GO:0032404 mismatch repair complex binding 4/1563 11/18639 0.363636363636364 4.336415983249 0.0100580273053041 0.0885392156907358 GO:0140297 DNA-binding transcription factor binding 56/1563 488/18639 0.114754098360656 1.36845914225481 0.0100965772278909 0.0885392156907358 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 11/1563 60/18639 0.183333333333333 2.1862763915547 0.0103831533419477 0.0903572122887054 GO:1990226 histone methyltransferase binding 5/1563 17/18639 0.294117647058824 3.50739528056904 0.0108398899095912 0.0936172310373788 GO:0043531 ADP binding 8/1563 38/18639 0.210526315789474 2.510556621881 0.0120943296301267 0.103665682543943 GO:0050699 WW domain binding 6/1563 24/18639 0.25 2.98128598848369 0.012419718296133 0.105660289982027 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 10/1563 54/18639 0.185185185185185 2.2083599914694 0.0132574889235304 0.11195212868759 GO:0016835 carbon-oxygen lyase activity 13/1563 79/18639 0.164556962025316 1.96236546077407 0.0138237309973553 0.115875392183714 GO:0017166 vinculin binding 4/1563 12/18639 0.333333333333333 3.97504798464491 0.0140990866647241 0.117320867137121 GO:0031369 translation initiation factor binding 7/1563 32/18639 0.21875 2.60862523992322 0.0150117551513443 0.124010151250235 GO:0004532 RNA exonuclease activity 8/1563 40/18639 0.2 2.38502879078695 0.0163953587800976 0.134465532441088 GO:0030170 pyridoxal phosphate binding 10/1563 56/18639 0.178571428571429 2.12948999177406 0.0169532813993629 0.138048148537669 GO:0030506 ankyrin binding 5/1563 19/18639 0.263157894736842 3.13819577735125 0.0177053730040701 0.143149824288227 GO:0008143 poly(A) binding 6/1563 26/18639 0.230769230769231 2.75195629706186 0.0184030307701746 0.147742641394359 GO:0019104 DNA N-glycosylase activity 4/1563 13/18639 0.307692307692308 3.66927506274915 0.0190362066981223 0.149876199429008 GO:0140666 annealing activity 4/1563 13/18639 0.307692307692308 3.66927506274915 0.0190362066981223 0.149876199429008 GO:0070279 vitamin B6 binding 10/1563 57/18639 0.175438596491228 2.09213051823416 0.0190632008045667 0.149876199429008 GO:0008408 3'-5' exonuclease activity 10/1563 58/18639 0.172413793103448 2.05605930240254 0.0213593292268071 0.166450497055901 GO:0015399 primary active transmembrane transporter activity 22/1563 166/18639 0.132530120481928 1.5804407649793 0.0214633535677346 0.166450497055901 GO:0000339 RNA cap binding 5/1563 20/18639 0.25 2.98128598848369 0.0220155469439017 0.168441097423141 GO:0140664 ATP-dependent DNA damage sensor activity 5/1563 20/18639 0.25 2.98128598848369 0.0220155469439017 0.168441097423141 GO:0045309 protein phosphorylated amino acid binding 10/1563 59/18639 0.169491525423729 2.02121083964996 0.0238500362545991 0.180733275720668 GO:0000175 3'-5'-RNA exonuclease activity 7/1563 35/18639 0.2 2.38502879078695 0.024097770096089 0.180733275720668 GO:0034061 DNA polymerase activity 7/1563 35/18639 0.2 2.38502879078695 0.024097770096089 0.180733275720668 GO:0044548 S100 protein binding 4/1563 14/18639 0.285714285714286 3.4071839868385 0.0249172534012797 0.185657966519339 GO:0031072 heat shock protein binding 18/1563 131/18639 0.137404580152672 1.63856939825058 0.0254719149084576 0.18855833114053 GO:0016866 intramolecular transferase activity 6/1563 28/18639 0.214285714285714 2.55538799012887 0.0261030333533984 0.190754610844972 GO:0051540 metal cluster binding 12/1563 77/18639 0.155844155844156 1.858463992821 0.0261032625366803 0.190754610844972 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 7/1563 36/18639 0.194444444444444 2.31877799104287 0.0278180217826872 0.199449967498512 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 7/1563 36/18639 0.194444444444444 2.31877799104287 0.0278180217826872 0.199449967498512 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 7/1563 36/18639 0.194444444444444 2.31877799104287 0.0278180217826872 0.199449967498512 GO:0031386 protein tag activity 4/1563 15/18639 0.266666666666667 3.18003838771593 0.03177569490222 0.223606741904511 GO:0050780 dopamine receptor binding 4/1563 15/18639 0.266666666666667 3.18003838771593 0.03177569490222 0.223606741904511 GO:0141047 molecular tag activity 4/1563 15/18639 0.266666666666667 3.18003838771593 0.03177569490222 0.223606741904511 GO:0004857 enzyme inhibitor activity 46/1563 416/18639 0.110576923076923 1.31864572567548 0.0324699108668898 0.22709017416107 GO:0008187 poly-pyrimidine tract binding 6/1563 30/18639 0.2 2.38502879078695 0.0356840810264288 0.246899317556863 GO:0030291 protein serine/threonine kinase inhibitor activity 8/1563 46/18639 0.173913043478261 2.07393807894517 0.0357354275411249 0.246899317556863 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 7/1563 38/18639 0.184210526315789 2.19673704414587 0.0363831808303333 0.249860398473373 GO:0003887 DNA-directed DNA polymerase activity 5/1563 23/18639 0.217391304347826 2.59242259868147 0.0387989979914653 0.262671267576566 GO:0008171 O-methyltransferase activity 5/1563 23/18639 0.217391304347826 2.59242259868147 0.0387989979914653 0.262671267576566 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 17/1563 128/18639 0.1328125 1.58380818138196 0.0389525164163364 0.262671267576566 GO:0004536 DNA nuclease activity 10/1563 64/18639 0.15625 1.8633037428023 0.0394931177984345 0.262671267576566 GO:0008142 oxysterol binding 4/1563 16/18639 0.25 2.98128598848369 0.0396311035290959 0.262671267576566 GO:0097027 ubiquitin-protein transferase activator activity 4/1563 16/18639 0.25 2.98128598848369 0.0396311035290959 0.262671267576566 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 7/1563 39/18639 0.179487179487179 2.14041045327034 0.0412519114781356 0.270271144167096 GO:0016776 phosphotransferase activity, phosphate group as acceptor 7/1563 39/18639 0.179487179487179 2.14041045327034 0.0412519114781356 0.270271144167096 GO:0003680 minor groove of adenine-thymine-rich DNA binding 3/1563 10/18639 0.3 3.57754318618042 0.0451521316163886 0.284383591396038 GO:0005345 purine nucleobase transmembrane transporter activity 3/1563 10/18639 0.3 3.57754318618042 0.0451521316163886 0.284383591396038 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 3/1563 10/18639 0.3 3.57754318618042 0.0451521316163886 0.284383591396038 GO:0008641 ubiquitin-like modifier activating enzyme activity 3/1563 10/18639 0.3 3.57754318618042 0.0451521316163886 0.284383591396038 GO:0016868 intramolecular phosphotransferase activity 3/1563 10/18639 0.3 3.57754318618042 0.0451521316163886 0.284383591396038 GO:0051880 G-quadruplex DNA binding 3/1563 10/18639 0.3 3.57754318618042 0.0451521316163886 0.284383591396038 GO:0098505 G-rich strand telomeric DNA binding 3/1563 10/18639 0.3 3.57754318618042 0.0451521316163886 0.284383591396038 GO:0001091 RNA polymerase II general transcription initiation factor binding 5/1563 24/18639 0.208333333333333 2.48440499040307 0.0457409137007633 0.284943396824427 GO:0140612 DNA damage sensor activity 5/1563 24/18639 0.208333333333333 2.48440499040307 0.0457409137007633 0.284943396824427 GO:0051219 phosphoprotein binding 13/1563 93/18639 0.139784946236559 1.666955606464 0.0463494755951642 0.287165229230909 GO:0004860 protein kinase inhibitor activity 12/1563 84/18639 0.142857142857143 1.70359199341925 0.047098897790252 0.289705932962841 GO:0070717 poly-purine tract binding 6/1563 32/18639 0.1875 2.23596449136276 0.0472678101149898 0.289705932962841 GO:0016018 cyclosporin A binding 4/1563 17/18639 0.235294117647059 2.80591622445523 0.0484899384889435 0.294034733390402 GO:0051787 misfolded protein binding 4/1563 17/18639 0.235294117647059 2.80591622445523 0.0484899384889435 0.294034733390402 GO:0051536 iron-sulfur cluster binding 11/1563 76/18639 0.144736842105263 1.72600767754319 0.0514991107162099 0.310629556700949 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 5/1563 25/18639 0.2 2.38502879078695 0.0533740003246791 0.318567331780807 GO:0017056 structural constituent of nuclear pore 5/1563 25/18639 0.2 2.38502879078695 0.0533740003246791 0.318567331780807 GO:0070063 RNA polymerase binding 9/1563 59/18639 0.152542372881356 1.81908975568496 0.0560526983546071 0.327660291613329 GO:0004520 DNA endonuclease activity 7/1563 42/18639 0.166666666666667 1.98752399232246 0.0583100684851916 0.327660291613329 GO:0016859 cis-trans isomerase activity 7/1563 42/18639 0.166666666666667 1.98752399232246 0.0583100684851916 0.327660291613329 GO:0051879 Hsp90 protein binding 7/1563 42/18639 0.166666666666667 1.98752399232246 0.0583100684851916 0.327660291613329 GO:0002162 dystroglycan binding 3/1563 11/18639 0.272727272727273 3.25231198743675 0.0583124207330453 0.327660291613329 GO:0005536 D-glucose binding 3/1563 11/18639 0.272727272727273 3.25231198743675 0.0583124207330453 0.327660291613329 GO:0015205 nucleobase transmembrane transporter activity 3/1563 11/18639 0.272727272727273 3.25231198743675 0.0583124207330453 0.327660291613329 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 3/1563 11/18639 0.272727272727273 3.25231198743675 0.0583124207330453 0.327660291613329 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 3/1563 11/18639 0.272727272727273 3.25231198743675 0.0583124207330453 0.327660291613329 GO:0050786 RAGE receptor binding 3/1563 11/18639 0.272727272727273 3.25231198743675 0.0583124207330453 0.327660291613329 GO:0050998 nitric-oxide synthase binding 3/1563 11/18639 0.272727272727273 3.25231198743675 0.0583124207330453 0.327660291613329 GO:0003746 translation elongation factor activity 4/1563 18/18639 0.222222222222222 2.65003198976328 0.0583465256118471 0.327660291613329 GO:0005048 signal sequence binding 8/1563 51/18639 0.156862745098039 1.87061081630349 0.0605154186547193 0.337375120938352 GO:0030332 cyclin binding 6/1563 34/18639 0.176470588235294 2.10443716834143 0.0609293199437209 0.337375120938352 GO:0001098 basal transcription machinery binding 9/1563 60/18639 0.15 1.78877159309021 0.0612602193282797 0.337375120938352 GO:0001099 basal RNA polymerase II transcription machinery binding 9/1563 60/18639 0.15 1.78877159309021 0.0612602193282797 0.337375120938352 GO:0004529 DNA exonuclease activity 5/1563 26/18639 0.192307692307692 2.29329691421822 0.0617004216471802 0.338165772489353 GO:0016651 oxidoreductase activity, acting on NAD(P)H 12/1563 88/18639 0.136363636363636 1.62615599371837 0.0632449879038098 0.344972661293508 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 7/1563 43/18639 0.162790697674419 1.94130250412891 0.0648328318915085 0.350509825369411 GO:0008186 ATP-dependent activity, acting on RNA 11/1563 79/18639 0.139240506329114 1.66046308219344 0.0648750641692507 0.350509825369411 GO:0097110 scaffold protein binding 10/1563 70/18639 0.142857142857143 1.70359199341925 0.0661178380305442 0.355539317711417 GO:0061631 ubiquitin conjugating enzyme activity 6/1563 35/18639 0.171428571428571 2.0443103921031 0.0685496406018516 0.366885400404276 GO:0050145 nucleoside monophosphate kinase activity 4/1563 19/18639 0.210526315789474 2.510556621881 0.0691841663072543 0.368337149393573 GO:0031490 chromatin DNA binding 16/1563 128/18639 0.125 1.49064299424184 0.0694670939645773 0.368337149393573 GO:0000049 tRNA binding 11/1563 80/18639 0.1375 1.63970729366603 0.069791193683322 0.368342411106422 GO:0008320 protein transmembrane transporter activity 5/1563 27/18639 0.185185185185185 2.2083599914694 0.070717054711648 0.371508951019718 GO:0019210 kinase inhibitor activity 12/1563 90/18639 0.133333333333333 1.59001919385797 0.0725381237868011 0.375122642259611 GO:0010853 cyclase activator activity 3/1563 12/18639 0.25 2.98128598848369 0.0730501987558189 0.375122642259611 GO:0043047 single-stranded telomeric DNA binding 3/1563 12/18639 0.25 2.98128598848369 0.0730501987558189 0.375122642259611 GO:0045295 gamma-catenin binding 3/1563 12/18639 0.25 2.98128598848369 0.0730501987558189 0.375122642259611 GO:0097371 MDM2/MDM4 family protein binding 3/1563 12/18639 0.25 2.98128598848369 0.0730501987558189 0.375122642259611 GO:0030295 protein kinase activator activity 17/1563 139/18639 0.122302158273381 1.45847084328698 0.0738478620954431 0.37751821878388 GO:0003925 G protein activity 8/1563 54/18639 0.148148148148148 1.76668799317552 0.0795413938957902 0.404808879648218 GO:0010851 cyclase regulator activity 4/1563 20/18639 0.2 2.38502879078695 0.0809763211480925 0.408464628800113 GO:0061608 nuclear import signal receptor activity 4/1563 20/18639 0.2 2.38502879078695 0.0809763211480925 0.408464628800113 GO:0003964 RNA-directed DNA polymerase activity 3/1563 13/18639 0.230769230769231 2.75195629706186 0.089254396373128 0.434842527040097 GO:0008253 5'-nucleotidase activity 3/1563 13/18639 0.230769230769231 2.75195629706186 0.089254396373128 0.434842527040097 GO:0009982 pseudouridine synthase activity 3/1563 13/18639 0.230769230769231 2.75195629706186 0.089254396373128 0.434842527040097 GO:0019855 calcium channel inhibitor activity 3/1563 13/18639 0.230769230769231 2.75195629706186 0.089254396373128 0.434842527040097 GO:0070700 BMP receptor binding 3/1563 13/18639 0.230769230769231 2.75195629706186 0.089254396373128 0.434842527040097 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 3/1563 13/18639 0.230769230769231 2.75195629706186 0.089254396373128 0.434842527040097 GO:0097157 pre-mRNA intronic binding 3/1563 13/18639 0.230769230769231 2.75195629706186 0.089254396373128 0.434842527040097 GO:0003714 transcription corepressor activity 23/1563 204/18639 0.112745098039216 1.34450152421813 0.0892571502871777 0.434842527040097 GO:0003785 actin monomer binding 5/1563 29/18639 0.172413793103448 2.05605930240254 0.0907836696178744 0.434846148589818 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 5/1563 29/18639 0.172413793103448 2.05605930240254 0.0907836696178744 0.434846148589818 GO:0097472 cyclin-dependent protein kinase activity 5/1563 29/18639 0.172413793103448 2.05605930240254 0.0907836696178744 0.434846148589818 GO:0106222 lncRNA binding 5/1563 29/18639 0.172413793103448 2.05605930240254 0.0907836696178744 0.434846148589818 GO:0051010 microtubule plus-end binding 4/1563 21/18639 0.19047619047619 2.27145599122567 0.0936878246776747 0.446879163734515 GO:0019003 GDP binding 10/1563 75/18639 0.133333333333333 1.59001919385797 0.0954349092328556 0.452127398941919 GO:0015078 proton transmembrane transporter activity 21/1563 185/18639 0.113513513513514 1.35366498936557 0.0955813185482477 0.452127398941919 GO:0016769 transferase activity, transferring nitrogenous groups 5/1563 30/18639 0.166666666666667 1.98752399232246 0.101803587336164 0.476986504829224 GO:0035925 mRNA 3'-UTR AU-rich region binding 5/1563 30/18639 0.166666666666667 1.98752399232246 0.101803587336164 0.476986504829224 GO:0017022 myosin binding 10/1563 76/18639 0.131578947368421 1.56909788867562 0.102091848402044 0.476986504829224 GO:0016779 nucleotidyltransferase activity 16/1563 136/18639 0.117647058823529 1.40295811222762 0.105293941102619 0.489939154518309 GO:0016530 metallochaperone activity 3/1563 14/18639 0.214285714285714 2.55538799012887 0.106800889910905 0.49093957459045 GO:0030983 mismatched DNA binding 3/1563 14/18639 0.214285714285714 2.55538799012887 0.106800889910905 0.49093957459045 GO:0098847 sequence-specific single stranded DNA binding 3/1563 14/18639 0.214285714285714 2.55538799012887 0.106800889910905 0.49093957459045 GO:0031683 G-protein beta/gamma-subunit complex binding 4/1563 22/18639 0.181818181818182 2.1682079916245 0.10727609741533 0.491143578528017 GO:0003724 RNA helicase activity 10/1563 77/18639 0.12987012987013 1.5487199940175 0.109011265763624 0.497091371882124 GO:0019209 kinase activator activity 17/1563 148/18639 0.114864864864865 1.36978004876277 0.114475939455202 0.519930561669047 GO:0004602 glutathione peroxidase activity 4/1563 23/18639 0.173913043478261 2.07393807894517 0.121692328872986 0.549082860696105 GO:0019842 vitamin binding 17/1563 150/18639 0.113333333333333 1.35151631477927 0.125037996318388 0.549082860696105 GO:0000774 adenyl-nucleotide exchange factor activity 3/1563 15/18639 0.2 2.38502879078695 0.125557188663076 0.549082860696105 GO:0004129 cytochrome-c oxidase activity 3/1563 15/18639 0.2 2.38502879078695 0.125557188663076 0.549082860696105 GO:0008252 nucleotidase activity 3/1563 15/18639 0.2 2.38502879078695 0.125557188663076 0.549082860696105 GO:0016846 carbon-sulfur lyase activity 3/1563 15/18639 0.2 2.38502879078695 0.125557188663076 0.549082860696105 GO:0033130 acetylcholine receptor binding 3/1563 15/18639 0.2 2.38502879078695 0.125557188663076 0.549082860696105 GO:0042809 nuclear vitamin D receptor binding 3/1563 15/18639 0.2 2.38502879078695 0.125557188663076 0.549082860696105 GO:0061578 K63-linked deubiquitinase activity 3/1563 15/18639 0.2 2.38502879078695 0.125557188663076 0.549082860696105 GO:0022884 macromolecule transmembrane transporter activity 5/1563 32/18639 0.15625 1.8633037428023 0.125711076001477 0.549082860696105 GO:0016830 carbon-carbon lyase activity 7/1563 51/18639 0.137254901960784 1.63678446426555 0.132060027817732 0.574612334779443 GO:0042056 chemoattractant activity 6/1563 42/18639 0.142857142857143 1.70359199341925 0.136218758958714 0.584442612638467 GO:0048487 beta-tubulin binding 6/1563 42/18639 0.142857142857143 1.70359199341925 0.136218758958714 0.584442612638467 GO:0140030 modification-dependent protein binding 19/1563 173/18639 0.109826589595376 1.30969789089457 0.136658287902914 0.584442612638467 GO:0005540 hyaluronic acid binding 4/1563 24/18639 0.166666666666667 1.98752399232246 0.136882611907431 0.584442612638467 GO:0070840 dynein complex binding 4/1563 24/18639 0.166666666666667 1.98752399232246 0.136882611907431 0.584442612638467 GO:0140299 molecular sensor activity 9/1563 71/18639 0.126760563380282 1.51163796599173 0.138344416411469 0.588479980257739 GO:0001618 virus receptor activity 10/1563 81/18639 0.123456790123457 1.47223999431293 0.139259748671554 0.590171425596922 GO:0008296 3'-5'-DNA exonuclease activity 3/1563 16/18639 0.1875 2.23596449136276 0.145386285232456 0.609339577812499 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/1563 16/18639 0.1875 2.23596449136276 0.145386285232456 0.609339577812499 GO:0034450 ubiquitin-ubiquitin ligase activity 3/1563 16/18639 0.1875 2.23596449136276 0.145386285232456 0.609339577812499 GO:0140272 exogenous protein binding 10/1563 82/18639 0.121951219512195 1.45428584804082 0.147445504033954 0.615706500361566 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 5/1563 34/18639 0.147058823529412 1.75369764028452 0.151928078508883 0.626672726697428 GO:0008483 transaminase activity 4/1563 25/18639 0.16 1.90802303262956 0.152789014113669 0.626672726697428 GO:0042974 nuclear retinoic acid receptor binding 4/1563 25/18639 0.16 1.90802303262956 0.152789014113669 0.626672726697428 GO:0034212 protein N-acetyltransferase activity 7/1563 53/18639 0.132075471698113 1.57501901278383 0.152820191247268 0.626672726697428 GO:0140296 general transcription initiation factor binding 7/1563 53/18639 0.132075471698113 1.57501901278383 0.152820191247268 0.626672726697428 GO:0035064 methylated histone binding 9/1563 74/18639 0.121621621621622 1.45035534574882 0.165415532455765 0.671669356173458 GO:0005092 GDP-dissociation inhibitor activity 3/1563 17/18639 0.176470588235294 2.10443716834143 0.166149788106066 0.671669356173458 GO:0017110 nucleoside diphosphate phosphatase activity 3/1563 17/18639 0.176470588235294 2.10443716834143 0.166149788106066 0.671669356173458 GO:0070402 NADPH binding 3/1563 17/18639 0.176470588235294 2.10443716834143 0.166149788106066 0.671669356173458 GO:0050681 nuclear androgen receptor binding 4/1563 26/18639 0.153846153846154 1.83463753137458 0.169350576380303 0.67978752490685 GO:0097602 cullin family protein binding 4/1563 26/18639 0.153846153846154 1.83463753137458 0.169350576380303 0.67978752490685 GO:0051539 4 iron, 4 sulfur cluster binding 6/1563 45/18639 0.133333333333333 1.59001919385797 0.17220478714902 0.688819148596079 GO:0000993 RNA polymerase II complex binding 5/1563 36/18639 0.138888888888889 1.65626999360205 0.180200052643018 0.71577721258899 GO:0044390 ubiquitin-like protein conjugating enzyme binding 5/1563 36/18639 0.138888888888889 1.65626999360205 0.180200052643018 0.71577721258899 GO:0140034 methylation-dependent protein binding 9/1563 76/18639 0.118421052631579 1.41218809980806 0.184746381531383 0.725389499286769 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 6/1563 46/18639 0.130434782608696 1.55545355920888 0.184994325676279 0.725389499286769 GO:0004364 glutathione transferase activity 4/1563 27/18639 0.148148148148148 1.76668799317552 0.186504232322678 0.725389499286769 GO:0008266 poly(U) RNA binding 4/1563 27/18639 0.148148148148148 1.76668799317552 0.186504232322678 0.725389499286769 GO:0000900 mRNA regulatory element binding translation repressor activity 3/1563 18/18639 0.166666666666667 1.98752399232246 0.18771044060491 0.725389499286769 GO:0008409 5'-3' exonuclease activity 3/1563 18/18639 0.166666666666667 1.98752399232246 0.18771044060491 0.725389499286769 GO:0031690 adrenergic receptor binding 3/1563 18/18639 0.166666666666667 1.98752399232246 0.18771044060491 0.725389499286769 GO:1990381 ubiquitin-specific protease binding 3/1563 18/18639 0.166666666666667 1.98752399232246 0.18771044060491 0.725389499286769 GO:0042805 actinin binding 5/1563 37/18639 0.135135135135135 1.61150593972091 0.195018119492847 0.748429398995843 GO:0061733 protein-lysine-acetyltransferase activity 6/1563 47/18639 0.127659574468085 1.52235880262997 0.198141941687179 0.748429398995843 GO:0016504 peptidase activator activity 7/1563 57/18639 0.12280701754386 1.46449136276392 0.198428374782952 0.748429398995843 GO:0005337 nucleoside transmembrane transporter activity 2/1563 10/18639 0.2 2.38502879078695 0.20220724113221 0.748429398995843 GO:0005522 profilin binding 2/1563 10/18639 0.2 2.38502879078695 0.20220724113221 0.748429398995843 GO:0008190 eukaryotic initiation factor 4E binding 2/1563 10/18639 0.2 2.38502879078695 0.20220724113221 0.748429398995843 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/1563 10/18639 0.2 2.38502879078695 0.20220724113221 0.748429398995843 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 2/1563 10/18639 0.2 2.38502879078695 0.20220724113221 0.748429398995843 GO:0030957 Tat protein binding 2/1563 10/18639 0.2 2.38502879078695 0.20220724113221 0.748429398995843 GO:0097177 mitochondrial ribosome binding 2/1563 10/18639 0.2 2.38502879078695 0.20220724113221 0.748429398995843 GO:0099122 RNA polymerase II C-terminal domain binding 2/1563 10/18639 0.2 2.38502879078695 0.20220724113221 0.748429398995843 GO:0140940 histone H2A methyltransferase activity 2/1563 10/18639 0.2 2.38502879078695 0.20220724113221 0.748429398995843 GO:1990259 histone H2AQ104 methyltransferase activity 2/1563 10/18639 0.2 2.38502879078695 0.20220724113221 0.748429398995843 GO:0046625 sphingolipid binding 4/1563 28/18639 0.142857142857143 1.70359199341925 0.204185645208638 0.750876243670475 GO:0046875 ephrin receptor binding 4/1563 28/18639 0.142857142857143 1.70359199341925 0.204185645208638 0.750876243670475 GO:1990841 promoter-specific chromatin binding 8/1563 68/18639 0.117647058823529 1.40295811222762 0.208199527447537 0.757721965127667 GO:0070003 threonine-type peptidase activity 3/1563 19/18639 0.157894736842105 1.88291746641075 0.20993411703572 0.757721965127667 GO:0097001 ceramide binding 3/1563 19/18639 0.157894736842105 1.88291746641075 0.20993411703572 0.757721965127667 GO:0140036 ubiquitin-modified protein reader activity 3/1563 19/18639 0.157894736842105 1.88291746641075 0.20993411703572 0.757721965127667 GO:0005109 frizzled binding 5/1563 38/18639 0.131578947368421 1.56909788867562 0.210240803044915 0.757721965127667 GO:0061980 regulatory RNA binding 7/1563 58/18639 0.120689655172414 1.43924151168178 0.210587822691702 0.757721965127667 GO:0003730 mRNA 3'-UTR binding 26/1563 262/18639 0.099236641221374 1.18341123206986 0.210699879776729 0.757721965127667 GO:0004540 RNA nuclease activity 13/1563 121/18639 0.107438016528926 1.28121381323266 0.213802893634367 0.7664632035949 GO:0008080 N-acetyltransferase activity 8/1563 69/18639 0.115942028985507 1.38262538596345 0.219547780323108 0.783247442955006 GO:0005506 iron ion binding 16/1563 154/18639 0.103896103896104 1.238975995214 0.219858931355791 0.783247442955006 GO:0043236 laminin binding 4/1563 29/18639 0.137931034482759 1.64484744192203 0.22232996130316 0.789583040142063 GO:0004518 nuclease activity 21/1563 209/18639 0.100478468899522 1.19822020589775 0.223082811262681 0.789796288321294 GO:0016763 pentosyltransferase activity 6/1563 49/18639 0.122448979591837 1.46022170864507 0.225410520614044 0.793111091049413 GO:0060590 ATPase regulator activity 6/1563 49/18639 0.122448979591837 1.46022170864507 0.225410520614044 0.793111091049413 GO:0042288 MHC class I protein binding 3/1563 20/18639 0.15 1.78877159309021 0.232691375133537 0.796924207139825 GO:0005525 GTP binding 36/1563 378/18639 0.0952380952380952 1.13572799561283 0.23415656133214 0.796924207139825 GO:0008199 ferric iron binding 2/1563 11/18639 0.181818181818182 2.1682079916245 0.23418386788758 0.796924207139825 GO:0015217 ADP transmembrane transporter activity 2/1563 11/18639 0.181818181818182 2.1682079916245 0.23418386788758 0.796924207139825 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/1563 11/18639 0.181818181818182 2.1682079916245 0.23418386788758 0.796924207139825 GO:0019206 nucleoside kinase activity 2/1563 11/18639 0.181818181818182 2.1682079916245 0.23418386788758 0.796924207139825 GO:0032794 GTPase activating protein binding 2/1563 11/18639 0.181818181818182 2.1682079916245 0.23418386788758 0.796924207139825 GO:0034713 type I transforming growth factor beta receptor binding 2/1563 11/18639 0.181818181818182 2.1682079916245 0.23418386788758 0.796924207139825 GO:0045294 alpha-catenin binding 2/1563 11/18639 0.181818181818182 2.1682079916245 0.23418386788758 0.796924207139825 GO:0048185 activin binding 2/1563 11/18639 0.181818181818182 2.1682079916245 0.23418386788758 0.796924207139825 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/1563 11/18639 0.181818181818182 2.1682079916245 0.23418386788758 0.796924207139825 GO:0004714 transmembrane receptor protein tyrosine kinase activity 7/1563 60/18639 0.116666666666667 1.39126679462572 0.235689561632038 0.799661012680129 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 5/1563 40/18639 0.125 1.49064299424184 0.241744467307416 0.815351161924419 GO:0050997 quaternary ammonium group binding 5/1563 40/18639 0.125 1.49064299424184 0.241744467307416 0.815351161924419 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 7/1563 61/18639 0.114754098360656 1.36845914225481 0.24859342754968 0.835977897954677 GO:0019200 carbohydrate kinase activity 3/1563 21/18639 0.142857142857143 1.70359199341925 0.255858633542847 0.837571030381312 GO:0035613 RNA stem-loop binding 3/1563 21/18639 0.142857142857143 1.70359199341925 0.255858633542847 0.837571030381312 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 3/1563 21/18639 0.142857142857143 1.70359199341925 0.255858633542847 0.837571030381312 GO:0051428 peptide hormone receptor binding 3/1563 21/18639 0.142857142857143 1.70359199341925 0.255858633542847 0.837571030381312 GO:0072542 protein phosphatase activator activity 3/1563 21/18639 0.142857142857143 1.70359199341925 0.255858633542847 0.837571030381312 GO:0001530 lipopolysaccharide binding 5/1563 41/18639 0.121951219512195 1.45428584804082 0.257946623039845 0.837571030381312 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 5/1563 41/18639 0.121951219512195 1.45428584804082 0.257946623039845 0.837571030381312 GO:0140318 protein transporter activity 5/1563 41/18639 0.121951219512195 1.45428584804082 0.257946623039845 0.837571030381312 GO:0008327 methyl-CpG binding 4/1563 31/18639 0.129032258064516 1.53872825212061 0.259749245511049 0.837571030381312 GO:0016410 N-acyltransferase activity 10/1563 94/18639 0.106382978723404 1.26863233552497 0.262341466495192 0.837571030381312 GO:0000340 RNA 7-methylguanosine cap binding 2/1563 12/18639 0.166666666666667 1.98752399232246 0.266410601713931 0.837571030381312 GO:0003720 telomerase activity 2/1563 12/18639 0.166666666666667 1.98752399232246 0.266410601713931 0.837571030381312 GO:0004859 phospholipase inhibitor activity 2/1563 12/18639 0.166666666666667 1.98752399232246 0.266410601713931 0.837571030381312 GO:0008179 adenylate cyclase binding 2/1563 12/18639 0.166666666666667 1.98752399232246 0.266410601713931 0.837571030381312 GO:0015368 calcium:monoatomic cation antiporter activity 2/1563 12/18639 0.166666666666667 1.98752399232246 0.266410601713931 0.837571030381312 GO:0016801 hydrolase activity, acting on ether bonds 2/1563 12/18639 0.166666666666667 1.98752399232246 0.266410601713931 0.837571030381312 GO:0016803 ether hydrolase activity 2/1563 12/18639 0.166666666666667 1.98752399232246 0.266410601713931 0.837571030381312 GO:0031543 peptidyl-proline dioxygenase activity 2/1563 12/18639 0.166666666666667 1.98752399232246 0.266410601713931 0.837571030381312 GO:0036009 protein-glutamine N-methyltransferase activity 2/1563 12/18639 0.166666666666667 1.98752399232246 0.266410601713931 0.837571030381312 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 2/1563 12/18639 0.166666666666667 1.98752399232246 0.266410601713931 0.837571030381312 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 2/1563 12/18639 0.166666666666667 1.98752399232246 0.266410601713931 0.837571030381312 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 2/1563 12/18639 0.166666666666667 1.98752399232246 0.266410601713931 0.837571030381312 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 2/1563 12/18639 0.166666666666667 1.98752399232246 0.266410601713931 0.837571030381312 GO:0042826 histone deacetylase binding 13/1563 127/18639 0.102362204724409 1.22068402678072 0.266700249147733 0.837571030381312 GO:0005080 protein kinase C binding 6/1563 52/18639 0.115384615384615 1.37597814853093 0.268351002713705 0.840439953553912 GO:0004402 histone acetyltransferase activity 5/1563 42/18639 0.119047619047619 1.41965999451604 0.27439633440216 0.850032122876257 GO:0019894 kinesin binding 5/1563 42/18639 0.119047619047619 1.41965999451604 0.27439633440216 0.850032122876257 GO:0035198 miRNA binding 5/1563 42/18639 0.119047619047619 1.41965999451604 0.27439633440216 0.850032122876257 GO:0043175 RNA polymerase core enzyme binding 5/1563 42/18639 0.119047619047619 1.41965999451604 0.27439633440216 0.850032122876257 GO:0042910 xenobiotic transmembrane transporter activity 4/1563 32/18639 0.125 1.49064299424184 0.278897555440988 0.855977684789781 GO:0043425 bHLH transcription factor binding 4/1563 32/18639 0.125 1.49064299424184 0.278897555440988 0.855977684789781 GO:0061133 endopeptidase activator activity 3/1563 22/18639 0.136363636363636 1.62615599371837 0.279319033984034 0.855977684789781 GO:0140035 ubiquitin-like protein reader activity 3/1563 22/18639 0.136363636363636 1.62615599371837 0.279319033984034 0.855977684789781 GO:0005246 calcium channel regulator activity 6/1563 53/18639 0.113207547169811 1.35001629667186 0.283099616943463 0.865237435162327 GO:0016407 acetyltransferase activity 10/1563 96/18639 0.104166666666667 1.24220249520154 0.28389257057053 0.865340990509101 GO:0019001 guanyl nucleotide binding 37/1563 400/18639 0.0925 1.10307581573896 0.288970446507125 0.868438101500404 GO:0032561 guanyl ribonucleotide binding 37/1563 400/18639 0.0925 1.10307581573896 0.288970446507125 0.868438101500404 GO:0004712 protein serine/threonine/tyrosine kinase activity 5/1563 43/18639 0.116279069767442 1.38664464580637 0.291054423765618 0.868438101500404 GO:0048156 tau protein binding 5/1563 43/18639 0.116279069767442 1.38664464580637 0.291054423765618 0.868438101500404 GO:0015485 cholesterol binding 6/1563 54/18639 0.111111111111111 1.32501599488164 0.298020312226073 0.868438101500404 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 4/1563 33/18639 0.121212121212121 1.44547199441633 0.298256403345724 0.868438101500404 GO:0140311 protein sequestering activity 4/1563 33/18639 0.121212121212121 1.44547199441633 0.298256403345724 0.868438101500404 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/1563 13/18639 0.153846153846154 1.83463753137458 0.298620820866806 0.868438101500404 GO:0005172 vascular endothelial growth factor receptor binding 2/1563 13/18639 0.153846153846154 1.83463753137458 0.298620820866806 0.868438101500404 GO:0005542 folic acid binding 2/1563 13/18639 0.153846153846154 1.83463753137458 0.298620820866806 0.868438101500404 GO:0030955 potassium ion binding 2/1563 13/18639 0.153846153846154 1.83463753137458 0.298620820866806 0.868438101500404 GO:0031432 titin binding 2/1563 13/18639 0.153846153846154 1.83463753137458 0.298620820866806 0.868438101500404 GO:0039706 co-receptor binding 2/1563 13/18639 0.153846153846154 1.83463753137458 0.298620820866806 0.868438101500404 GO:0043560 insulin receptor substrate binding 2/1563 13/18639 0.153846153846154 1.83463753137458 0.298620820866806 0.868438101500404 GO:0045159 myosin II binding 2/1563 13/18639 0.153846153846154 1.83463753137458 0.298620820866806 0.868438101500404 GO:0061459 L-arginine transmembrane transporter activity 2/1563 13/18639 0.153846153846154 1.83463753137458 0.298620820866806 0.868438101500404 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 2/1563 13/18639 0.153846153846154 1.83463753137458 0.298620820866806 0.868438101500404 GO:0140852 histone ubiquitin ligase activity 2/1563 13/18639 0.153846153846154 1.83463753137458 0.298620820866806 0.868438101500404 GO:0031681 G-protein beta-subunit binding 3/1563 23/18639 0.130434782608696 1.55545355920888 0.302963039750691 0.876593566791339 GO:0099186 structural constituent of postsynapse 3/1563 23/18639 0.130434782608696 1.55545355920888 0.302963039750691 0.876593566791339 GO:0032182 ubiquitin-like protein binding 12/1563 120/18639 0.1 1.19251439539347 0.305118639370977 0.880595566792187 GO:0140313 molecular sequestering activity 6/1563 55/18639 0.109090909090909 1.3009247949747 0.313085960253285 0.90130806739582 GO:0016831 carboxy-lyase activity 4/1563 34/18639 0.117647058823529 1.40295811222762 0.317766846657302 0.912479106270339 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 12/1563 122/18639 0.0983606557377049 1.17296497907555 0.325303956686368 0.930551907826617 GO:0015295 solute:proton symporter activity 3/1563 24/18639 0.125 1.49064299424184 0.326688815156871 0.930551907826617 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 3/1563 24/18639 0.125 1.49064299424184 0.326688815156871 0.930551907826617 GO:0019212 phosphatase inhibitor activity 6/1563 56/18639 0.107142857142857 1.27769399506444 0.328269724128409 0.930551907826617 GO:0019199 transmembrane receptor protein kinase activity 8/1563 78/18639 0.102564102564103 1.22309168758305 0.329928938960618 0.930551907826617 GO:0005347 ATP transmembrane transporter activity 2/1563 14/18639 0.142857142857143 1.70359199341925 0.330590809359456 0.930551907826617 GO:0008559 ABC-type xenobiotic transporter activity 2/1563 14/18639 0.142857142857143 1.70359199341925 0.330590809359456 0.930551907826617 GO:0070742 C2H2 zinc finger domain binding 2/1563 14/18639 0.142857142857143 1.70359199341925 0.330590809359456 0.930551907826617 GO:0005154 epidermal growth factor receptor binding 4/1563 35/18639 0.114285714285714 1.3628735947354 0.337372312699958 0.947301567679685 GO:0022804 active transmembrane transporter activity 41/1563 457/18639 0.0897155361050328 1.06987068295695 0.347749047827662 0.974039102023428 GO:0005537 D-mannose binding 3/1563 25/18639 0.12 1.43101727447217 0.350402424390035 0.974289667816195 GO:0008139 nuclear localization sequence binding 3/1563 25/18639 0.12 1.43101727447217 0.350402424390035 0.974289667816195 GO:0019211 phosphatase activator activity 3/1563 25/18639 0.12 1.43101727447217 0.350402424390035 0.974289667816195 GO:0002039 p53 binding 7/1563 69/18639 0.101449275362319 1.20979721271802 0.357652578241376 0.98711442330795 GO:0005504 fatty acid binding 5/1563 47/18639 0.106382978723404 1.26863233552497 0.359010164394059 0.98711442330795 GO:0004559 alpha-mannosidase activity 2/1563 15/18639 0.133333333333333 1.59001919385797 0.362134443312745 0.98711442330795 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/1563 15/18639 0.133333333333333 1.59001919385797 0.362134443312745 0.98711442330795 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/1563 15/18639 0.133333333333333 1.59001919385797 0.362134443312745 0.98711442330795 GO:0005523 tropomyosin binding 2/1563 15/18639 0.133333333333333 1.59001919385797 0.362134443312745 0.98711442330795 GO:0051371 muscle alpha-actinin binding 2/1563 15/18639 0.133333333333333 1.59001919385797 0.362134443312745 0.98711442330795 GO:0120283 protein serine/threonine kinase binding 2/1563 15/18639 0.133333333333333 1.59001919385797 0.362134443312745 0.98711442330795 GO:0016922 nuclear receptor binding 13/1563 137/18639 0.0948905109489051 1.13158300292811 0.362807845057922 0.98711442330795 GO:0001221 transcription coregulator binding 11/1563 115/18639 0.0956521739130435 1.14066594341984 0.370209921665686 0.999999999529632 GO:0030507 spectrin binding 3/1563 26/18639 0.115384615384615 1.37597814853093 0.374017882826087 0.999999999529632 GO:0070006 metalloaminopeptidase activity 3/1563 26/18639 0.115384615384615 1.37597814853093 0.374017882826087 0.999999999529632 GO:0046982 protein heterodimerization activity 33/1563 369/18639 0.0894308943089431 1.06647628856327 0.375121037088644 0.999999999529632 GO:0016879 ligase activity, forming carbon-nitrogen bonds 5/1563 48/18639 0.104166666666667 1.24220249520154 0.37614825145319 0.999999999529632 GO:0022829 wide pore channel activity 4/1563 37/18639 0.108108108108108 1.28920475177673 0.3766552968088 0.999999999529632 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 8/1563 82/18639 0.0975609756097561 1.16342867843266 0.381857415653999 0.999999999529632 GO:0019208 phosphatase regulator activity 11/1563 117/18639 0.094017094017094 1.12116738028446 0.392104555127434 0.999999999529632 GO:0004713 protein tyrosine kinase activity 13/1563 140/18639 0.0928571428571429 1.10733479572251 0.392758432988038 0.999999999529632 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/1563 16/18639 0.125 1.49064299424184 0.393098465895643 0.999999999529632 GO:0005159 insulin-like growth factor receptor binding 2/1563 16/18639 0.125 1.49064299424184 0.393098465895643 0.999999999529632 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1563 16/18639 0.125 1.49064299424184 0.393098465895643 0.999999999529632 GO:0005521 lamin binding 2/1563 16/18639 0.125 1.49064299424184 0.393098465895643 0.999999999529632 GO:0015923 mannosidase activity 2/1563 16/18639 0.125 1.49064299424184 0.393098465895643 0.999999999529632 GO:0030275 LRR domain binding 2/1563 16/18639 0.125 1.49064299424184 0.393098465895643 0.999999999529632 GO:0043023 ribosomal large subunit binding 2/1563 16/18639 0.125 1.49064299424184 0.393098465895643 0.999999999529632 GO:0055102 lipase inhibitor activity 2/1563 16/18639 0.125 1.49064299424184 0.393098465895643 0.999999999529632 GO:0140328 floppase activity 2/1563 16/18639 0.125 1.49064299424184 0.393098465895643 0.999999999529632 GO:0000146 microfilament motor activity 4/1563 38/18639 0.105263157894737 1.2552783109405 0.396233472545728 0.999999999529632 GO:0001671 ATPase activator activity 3/1563 27/18639 0.111111111111111 1.32501599488164 0.397457089139013 0.999999999529632 GO:0005385 zinc ion transmembrane transporter activity 3/1563 27/18639 0.111111111111111 1.32501599488164 0.397457089139013 0.999999999529632 GO:0023026 MHC class II protein complex binding 3/1563 27/18639 0.111111111111111 1.32501599488164 0.397457089139013 0.999999999529632 GO:0008276 protein methyltransferase activity 9/1563 95/18639 0.0947368421052632 1.12975047984645 0.402413302739153 0.999999999529632 GO:0019888 protein phosphatase regulator activity 10/1563 107/18639 0.0934579439252336 1.11449943494717 0.408696396906328 0.999999999529632 GO:0005006 epidermal growth factor receptor activity 5/1563 50/18639 0.1 1.19251439539347 0.410366242999157 0.999999999529632 GO:0005007 fibroblast growth factor receptor activity 5/1563 50/18639 0.1 1.19251439539347 0.410366242999157 0.999999999529632 GO:0020037 heme binding 13/1563 142/18639 0.0915492957746479 1.09173853099403 0.412842290866107 0.999999999529632 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 4/1563 39/18639 0.102564102564103 1.22309168758305 0.415708229347638 0.999999999529632 GO:0019789 SUMO transferase activity 3/1563 28/18639 0.107142857142857 1.27769399506444 0.420649662410658 0.999999999529632 GO:0046966 nuclear thyroid hormone receptor binding 3/1563 28/18639 0.107142857142857 1.27769399506444 0.420649662410658 0.999999999529632 GO:0051393 alpha-actinin binding 3/1563 28/18639 0.107142857142857 1.27769399506444 0.420649662410658 0.999999999529632 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/1563 17/18639 0.117647058823529 1.40295811222762 0.42335828960092 0.999999999529632 GO:0004659 prenyltransferase activity 2/1563 17/18639 0.117647058823529 1.40295811222762 0.42335828960092 0.999999999529632 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/1563 17/18639 0.117647058823529 1.40295811222762 0.42335828960092 0.999999999529632 GO:0030548 acetylcholine receptor regulator activity 2/1563 17/18639 0.117647058823529 1.40295811222762 0.42335828960092 0.999999999529632 GO:0032183 SUMO binding 2/1563 17/18639 0.117647058823529 1.40295811222762 0.42335828960092 0.999999999529632 GO:0032977 membrane insertase activity 2/1563 17/18639 0.117647058823529 1.40295811222762 0.42335828960092 0.999999999529632 GO:0046965 nuclear retinoid X receptor binding 2/1563 17/18639 0.117647058823529 1.40295811222762 0.42335828960092 0.999999999529632 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 12/1563 132/18639 0.0909090909090909 1.08410399581225 0.42926162243122 0.999999999529632 GO:0003924 GTPase activity 29/1563 331/18639 0.0876132930513595 1.04480113191573 0.430568076250803 0.999999999529632 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 2/1563 18/18639 0.111111111111111 1.32501599488164 0.452814270725421 0.999999999529632 GO:0008308 voltage-gated monoatomic anion channel activity 2/1563 18/18639 0.111111111111111 1.32501599488164 0.452814270725421 0.999999999529632 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/1563 18/18639 0.111111111111111 1.32501599488164 0.452814270725421 0.999999999529632 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/1563 18/18639 0.111111111111111 1.32501599488164 0.452814270725421 0.999999999529632 GO:0034185 apolipoprotein binding 2/1563 18/18639 0.111111111111111 1.32501599488164 0.452814270725421 0.999999999529632 GO:0070064 proline-rich region binding 2/1563 18/18639 0.111111111111111 1.32501599488164 0.452814270725421 0.999999999529632 GO:0099602 neurotransmitter receptor regulator activity 2/1563 18/18639 0.111111111111111 1.32501599488164 0.452814270725421 0.999999999529632 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/1563 41/18639 0.0975609756097561 1.16342867843266 0.45418249983031 0.999999999529632 GO:0016877 ligase activity, forming carbon-sulfur bonds 4/1563 41/18639 0.0975609756097561 1.16342867843266 0.45418249983031 0.999999999529632 GO:0004864 protein phosphatase inhibitor activity 5/1563 53/18639 0.0943396226415094 1.12501358055988 0.461094509448318 0.999999999529632 GO:0005003 ephrin receptor activity 5/1563 53/18639 0.0943396226415094 1.12501358055988 0.461094509448318 0.999999999529632 GO:0005005 transmembrane-ephrin receptor activity 5/1563 53/18639 0.0943396226415094 1.12501358055988 0.461094509448318 0.999999999529632 GO:0043130 ubiquitin binding 9/1563 100/18639 0.09 1.07326295585413 0.463540252061338 0.999999999529632 GO:0001965 G-protein alpha-subunit binding 3/1563 30/18639 0.1 1.19251439539347 0.466050507565153 0.999999999529632 GO:0001968 fibronectin binding 3/1563 30/18639 0.1 1.19251439539347 0.466050507565153 0.999999999529632 GO:0033612 receptor serine/threonine kinase binding 3/1563 30/18639 0.1 1.19251439539347 0.466050507565153 0.999999999529632 GO:0098918 structural constituent of synapse 3/1563 30/18639 0.1 1.19251439539347 0.466050507565153 0.999999999529632 GO:0140789 histone phosphatase activity 12/1563 136/18639 0.0882352941176471 1.05221858417071 0.471118256759917 0.999999999529632 GO:0050661 NADP binding 5/1563 54/18639 0.0925925925925926 1.1041799957347 0.477734733654671 0.999999999529632 GO:0051287 NAD binding 5/1563 54/18639 0.0925925925925926 1.1041799957347 0.477734733654671 0.999999999529632 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/1563 19/18639 0.105263157894737 1.2552783109405 0.481388406453622 0.999999999529632 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/1563 19/18639 0.105263157894737 1.2552783109405 0.481388406453622 0.999999999529632 GO:0015245 fatty acid transmembrane transporter activity 2/1563 19/18639 0.105263157894737 1.2552783109405 0.481388406453622 0.999999999529632 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/1563 19/18639 0.105263157894737 1.2552783109405 0.481388406453622 0.999999999529632 GO:0031420 alkali metal ion binding 2/1563 19/18639 0.105263157894737 1.2552783109405 0.481388406453622 0.999999999529632 GO:0042800 histone H3K4 methyltransferase activity 2/1563 19/18639 0.105263157894737 1.2552783109405 0.481388406453622 0.999999999529632 GO:0046624 sphingolipid transporter activity 2/1563 19/18639 0.105263157894737 1.2552783109405 0.481388406453622 0.999999999529632 GO:0008200 ion channel inhibitor activity 4/1563 43/18639 0.0930232558139535 1.10931571664509 0.491779455306338 0.999999999529632 GO:0042054 histone methyltransferase activity 6/1563 67/18639 0.0895522388059701 1.06792333915833 0.496007632176231 0.999999999529632 GO:0046332 SMAD binding 7/1563 79/18639 0.0886075949367089 1.05665832503219 0.497452410892574 0.999999999529632 GO:0004722 protein serine/threonine phosphatase activity 9/1563 103/18639 0.087378640776699 1.04200286976129 0.499699003220756 0.999999999529632 GO:0035401 histone H3Y41 kinase activity 10/1563 115/18639 0.0869565217391304 1.03696903947259 0.500615600783391 0.999999999529632 GO:0140801 histone H2AXY142 kinase activity 10/1563 115/18639 0.0869565217391304 1.03696903947259 0.500615600783391 0.999999999529632 GO:0004721 phosphoprotein phosphatase activity 15/1563 175/18639 0.0857142857142857 1.02215519605155 0.504104988620625 0.999999999529632 GO:0031406 carboxylic acid binding 16/1563 187/18639 0.0855614973262032 1.02033317252918 0.504664654570033 0.999999999529632 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/1563 20/18639 0.1 1.19251439539347 0.509021409933631 0.999999999529632 GO:0005326 neurotransmitter transmembrane transporter activity 2/1563 20/18639 0.1 1.19251439539347 0.509021409933631 0.999999999529632 GO:0015095 magnesium ion transmembrane transporter activity 2/1563 20/18639 0.1 1.19251439539347 0.509021409933631 0.999999999529632 GO:0016408 C-acyltransferase activity 2/1563 20/18639 0.1 1.19251439539347 0.509021409933631 0.999999999529632 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/1563 20/18639 0.1 1.19251439539347 0.509021409933631 0.999999999529632 GO:0030742 GTP-dependent protein binding 2/1563 20/18639 0.1 1.19251439539347 0.509021409933631 0.999999999529632 GO:0031418 L-ascorbic acid binding 2/1563 20/18639 0.1 1.19251439539347 0.509021409933631 0.999999999529632 GO:0052745 inositol phosphate phosphatase activity 2/1563 20/18639 0.1 1.19251439539347 0.509021409933631 0.999999999529632 GO:0008378 galactosyltransferase activity 3/1563 32/18639 0.09375 1.11798224568138 0.509801454776513 0.999999999529632 GO:0051059 NF-kappaB binding 3/1563 32/18639 0.09375 1.11798224568138 0.509801454776513 0.999999999529632 GO:0001046 core promoter sequence-specific DNA binding 4/1563 44/18639 0.0909090909090909 1.08410399581225 0.510169175473897 0.999999999529632 GO:0016248 channel inhibitor activity 4/1563 44/18639 0.0909090909090909 1.08410399581225 0.510169175473897 0.999999999529632 GO:0030145 manganese ion binding 6/1563 68/18639 0.0882352941176471 1.05221858417071 0.510752698525366 0.999999999529632 GO:0032934 sterol binding 6/1563 68/18639 0.0882352941176471 1.05221858417071 0.510752698525366 0.999999999529632 GO:0048306 calcium-dependent protein binding 7/1563 80/18639 0.0875 1.04345009596929 0.51103671106759 0.999999999529632 GO:0046906 tetrapyrrole binding 13/1563 152/18639 0.0855263157894737 1.01991362763916 0.512718323161167 0.999999999529632 GO:0043177 organic acid binding 16/1563 189/18639 0.0846560846560847 1.0095359961003 0.522337853303174 0.999999999529632 GO:0015101 organic cation transmembrane transporter activity 7/1563 81/18639 0.0864197530864197 1.03056799601905 0.524491178755055 0.999999999529632 GO:0033192 calmodulin-dependent protein phosphatase activity 7/1563 81/18639 0.0864197530864197 1.03056799601905 0.524491178755055 0.999999999529632 GO:0140791 histone H2AXS140 phosphatase activity 7/1563 81/18639 0.0864197530864197 1.03056799601905 0.524491178755055 0.999999999529632 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 7/1563 81/18639 0.0864197530864197 1.03056799601905 0.524491178755055 0.999999999529632 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 7/1563 81/18639 0.0864197530864197 1.03056799601905 0.524491178755055 0.999999999529632 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 7/1563 81/18639 0.0864197530864197 1.03056799601905 0.524491178755055 0.999999999529632 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 7/1563 81/18639 0.0864197530864197 1.03056799601905 0.524491178755055 0.999999999529632 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 7/1563 81/18639 0.0864197530864197 1.03056799601905 0.524491178755055 0.999999999529632 GO:1990439 MAP kinase serine/threonine phosphatase activity 7/1563 81/18639 0.0864197530864197 1.03056799601905 0.524491178755055 0.999999999529632 GO:0046915 transition metal ion transmembrane transporter activity 4/1563 45/18639 0.0888888888888889 1.06001279590531 0.528249881672232 0.999999999529632 GO:0141110 transporter inhibitor activity 4/1563 45/18639 0.0888888888888889 1.06001279590531 0.528249881672232 0.999999999529632 GO:0061134 peptidase regulator activity 19/1563 226/18639 0.084070796460177 1.00255635010956 0.530431395995958 0.999999999529632 GO:0140416 transcription regulator inhibitor activity 3/1563 33/18639 0.0909090909090909 1.08410399581225 0.530955959919591 0.999999999529632 GO:0019902 phosphatase binding 16/1563 190/18639 0.0842105263157895 1.0042226487524 0.531111997013464 0.999999999529632 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/1563 21/18639 0.0952380952380952 1.13572799561283 0.535670123237925 0.999999999529632 GO:0001846 opsonin binding 2/1563 21/18639 0.0952380952380952 1.13572799561283 0.535670123237925 0.999999999529632 GO:0008373 sialyltransferase activity 2/1563 21/18639 0.0952380952380952 1.13572799561283 0.535670123237925 0.999999999529632 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/1563 21/18639 0.0952380952380952 1.13572799561283 0.535670123237925 0.999999999529632 GO:0015174 basic amino acid transmembrane transporter activity 2/1563 21/18639 0.0952380952380952 1.13572799561283 0.535670123237925 0.999999999529632 GO:1904047 S-adenosyl-L-methionine binding 2/1563 21/18639 0.0952380952380952 1.13572799561283 0.535670123237925 0.999999999529632 GO:0033549 MAP kinase phosphatase activity 7/1563 82/18639 0.0853658536585366 1.01800009362858 0.537803663311154 0.999999999529632 GO:0016741 transferase activity, transferring one-carbon groups 18/1563 215/18639 0.0837209302325581 0.998384144980583 0.538853795437132 0.999999999529632 GO:0016874 ligase activity 14/1563 167/18639 0.0838323353293413 0.999712666796924 0.541126913919453 0.999999999529632 GO:0004674 protein serine/threonine kinase activity 36/1563 433/18639 0.0831408775981524 0.991466933814436 0.547419952316707 0.999999999529632 GO:0106310 protein serine kinase activity 30/1563 361/18639 0.0831024930747922 0.991009192847762 0.548873310462153 0.999999999529632 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 29/1563 349/18639 0.0830945558739255 0.990914540584835 0.549188833181754 0.999999999529632 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 7/1563 83/18639 0.0843373493975904 1.00573503225956 0.550962759959982 0.999999999529632 GO:0008376 acetylgalactosaminyltransferase activity 3/1563 34/18639 0.0882352941176471 1.05221858417071 0.551587164428845 0.999999999529632 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 3/1563 34/18639 0.0882352941176471 1.05221858417071 0.551587164428845 0.999999999529632 GO:0051427 hormone receptor binding 3/1563 34/18639 0.0882352941176471 1.05221858417071 0.551587164428845 0.999999999529632 GO:0090482 vitamin transmembrane transporter activity 3/1563 34/18639 0.0882352941176471 1.05221858417071 0.551587164428845 0.999999999529632 GO:0019903 protein phosphatase binding 12/1563 144/18639 0.0833333333333333 0.993761996161228 0.552834857212346 0.999999999529632 GO:0031593 polyubiquitin modification-dependent protein binding 5/1563 59/18639 0.0847457627118644 1.01060541982498 0.557893135745723 0.999999999529632 GO:0140098 catalytic activity, acting on RNA 32/1563 387/18639 0.082687338501292 0.986058414795637 0.560564291314455 0.999999999529632 GO:0008649 rRNA methyltransferase activity 2/1563 22/18639 0.0909090909090909 1.08410399581225 0.561305232163314 0.999999999529632 GO:0034062 5'-3' RNA polymerase activity 2/1563 22/18639 0.0909090909090909 1.08410399581225 0.561305232163314 0.999999999529632 GO:0097747 RNA polymerase activity 2/1563 22/18639 0.0909090909090909 1.08410399581225 0.561305232163314 0.999999999529632 GO:0001784 phosphotyrosine residue binding 4/1563 47/18639 0.0851063829787234 1.01490586841998 0.563392021099235 0.999999999529632 GO:0043495 protein-membrane adaptor activity 4/1563 47/18639 0.0851063829787234 1.01490586841998 0.563392021099235 0.999999999529632 GO:0140938 histone H3 methyltransferase activity 4/1563 47/18639 0.0851063829787234 1.01490586841998 0.563392021099235 0.999999999529632 GO:0017018 myosin phosphatase activity 7/1563 84/18639 0.0833333333333333 0.993761996161228 0.563957811353375 0.999999999529632 GO:0005518 collagen binding 6/1563 72/18639 0.0833333333333333 0.993761996161228 0.567949212418789 0.999999999529632 GO:0010485 histone H4 acetyltransferase activity 3/1563 35/18639 0.0857142857142857 1.02215519605155 0.571669806778429 0.999999999529632 GO:0016229 steroid dehydrogenase activity 3/1563 35/18639 0.0857142857142857 1.02215519605155 0.571669806778429 0.999999999529632 GO:0043015 gamma-tubulin binding 3/1563 35/18639 0.0857142857142857 1.02215519605155 0.571669806778429 0.999999999529632 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 5/1563 60/18639 0.0833333333333333 0.993761996161228 0.573186534473529 0.999999999529632 GO:0140693 molecular condensate scaffold activity 4/1563 48/18639 0.0833333333333333 0.993761996161228 0.580414181976149 0.999999999529632 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0004090 carbonyl reductase (NADPH) activity 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0004955 prostaglandin receptor activity 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0005528 FK506 binding 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0008519 ammonium channel activity 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0019911 structural constituent of myelin sheath 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0031996 thioesterase binding 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0032052 bile acid binding 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0033204 ribonuclease P RNA binding 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0035374 chondroitin sulfate binding 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0042975 peroxisome proliferator activated receptor binding 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0043121 neurotrophin binding 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0043422 protein kinase B binding 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0140999 histone H3K4 trimethyltransferase activity 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0141109 transporter activator activity 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:1990757 ubiquitin ligase activator activity 1/1563 10/18639 0.1 1.19251439539347 0.583572529112867 0.999999999529632 GO:0000295 adenine nucleotide transmembrane transporter activity 2/1563 23/18639 0.0869565217391304 1.03696903947259 0.585909250488325 0.999999999529632 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/1563 23/18639 0.0869565217391304 1.03696903947259 0.585909250488325 0.999999999529632 GO:0043274 phospholipase binding 2/1563 23/18639 0.0869565217391304 1.03696903947259 0.585909250488325 0.999999999529632 GO:0070577 lysine-acetylated histone binding 2/1563 23/18639 0.0869565217391304 1.03696903947259 0.585909250488325 0.999999999529632 GO:0140102 catalytic activity, acting on a rRNA 2/1563 23/18639 0.0869565217391304 1.03696903947259 0.585909250488325 0.999999999529632 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/1563 23/18639 0.0869565217391304 1.03696903947259 0.585909250488325 0.999999999529632 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/1563 36/18639 0.0833333333333333 0.993761996161228 0.591183530557642 0.999999999529632 GO:0019838 growth factor binding 11/1563 136/18639 0.0808823529411765 0.964533702156486 0.595081197856124 0.999999999529632 GO:0001222 transcription corepressor binding 4/1563 49/18639 0.0816326530612245 0.973481139096713 0.59704855023638 0.999999999529632 GO:0005004 GPI-linked ephrin receptor activity 4/1563 49/18639 0.0816326530612245 0.973481139096713 0.59704855023638 0.999999999529632 GO:0005008 hepatocyte growth factor receptor activity 4/1563 49/18639 0.0816326530612245 0.973481139096713 0.59704855023638 0.999999999529632 GO:0005009 insulin receptor activity 4/1563 49/18639 0.0816326530612245 0.973481139096713 0.59704855023638 0.999999999529632 GO:0005011 macrophage colony-stimulating factor receptor activity 4/1563 49/18639 0.0816326530612245 0.973481139096713 0.59704855023638 0.999999999529632 GO:0005018 platelet-derived growth factor alpha-receptor activity 4/1563 49/18639 0.0816326530612245 0.973481139096713 0.59704855023638 0.999999999529632 GO:0005020 stem cell factor receptor activity 4/1563 49/18639 0.0816326530612245 0.973481139096713 0.59704855023638 0.999999999529632 GO:0008288 boss receptor activity 4/1563 49/18639 0.0816326530612245 0.973481139096713 0.59704855023638 0.999999999529632 GO:0036332 placental growth factor receptor activity 4/1563 49/18639 0.0816326530612245 0.973481139096713 0.59704855023638 0.999999999529632 GO:0038062 protein tyrosine kinase collagen receptor activity 4/1563 49/18639 0.0816326530612245 0.973481139096713 0.59704855023638 0.999999999529632 GO:0060175 brain-derived neurotrophic factor receptor activity 4/1563 49/18639 0.0816326530612245 0.973481139096713 0.59704855023638 0.999999999529632 GO:0015149 hexose transmembrane transporter activity 2/1563 24/18639 0.0833333333333333 0.993761996161228 0.609474744609367 0.999999999529632 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/1563 24/18639 0.0833333333333333 0.993761996161228 0.609474744609367 0.999999999529632 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/1563 24/18639 0.0833333333333333 0.993761996161228 0.609474744609367 0.999999999529632 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/1563 24/18639 0.0833333333333333 0.993761996161228 0.609474744609367 0.999999999529632 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/1563 24/18639 0.0833333333333333 0.993761996161228 0.609474744609367 0.999999999529632 GO:0050431 transforming growth factor beta binding 2/1563 24/18639 0.0833333333333333 0.993761996161228 0.609474744609367 0.999999999529632 GO:0055056 D-glucose transmembrane transporter activity 2/1563 24/18639 0.0833333333333333 0.993761996161228 0.609474744609367 0.999999999529632 GO:0140033 acetylation-dependent protein binding 2/1563 24/18639 0.0833333333333333 0.993761996161228 0.609474744609367 0.999999999529632 GO:0023023 MHC protein complex binding 3/1563 37/18639 0.0810810810810811 0.966903563832547 0.610112492359011 0.999999999529632 GO:0005017 platelet-derived growth factor receptor activity 4/1563 50/18639 0.08 0.954011516314779 0.613281794343964 0.999999999529632 GO:0005019 platelet-derived growth factor beta-receptor activity 4/1563 50/18639 0.08 0.954011516314779 0.613281794343964 0.999999999529632 GO:0004197 cysteine-type endopeptidase activity 7/1563 88/18639 0.0795454545454545 0.948590996335718 0.614110395240995 0.999999999529632 GO:0005507 copper ion binding 5/1563 63/18639 0.0793650793650794 0.946439996344027 0.617329569511868 0.999999999529632 GO:0000099 sulfur amino acid transmembrane transporter activity 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0004954 prostanoid receptor activity 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0005114 type II transforming growth factor beta receptor binding 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0005225 volume-sensitive anion channel activity 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0008046 axon guidance receptor activity 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0008432 JUN kinase binding 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0015173 aromatic amino acid transmembrane transporter activity 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0016594 glycine binding 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0034056 estrogen response element binding 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0035252 UDP-xylosyltransferase activity 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0042285 xylosyltransferase activity 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0042608 T cell receptor binding 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0043522 leucine zipper domain binding 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0047676 arachidonate-CoA ligase activity 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0140031 phosphorylation-dependent protein binding 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0140537 transcription regulator activator activity 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/1563 11/18639 0.0909090909090909 1.08410399581225 0.618511395235396 0.999999999529632 GO:0005010 insulin-like growth factor receptor activity 4/1563 51/18639 0.0784313725490196 0.935305408151744 0.629102872878865 0.999999999529632 GO:0005021 vascular endothelial growth factor receptor activity 4/1563 51/18639 0.0784313725490196 0.935305408151744 0.629102872878865 0.999999999529632 GO:0005030 neurotrophin receptor activity 4/1563 51/18639 0.0784313725490196 0.935305408151744 0.629102872878865 0.999999999529632 GO:0004519 endonuclease activity 10/1563 127/18639 0.078740157480315 0.938987712908247 0.629328328370365 0.999999999529632 GO:0019783 ubiquitin-like protein peptidase activity 10/1563 127/18639 0.078740157480315 0.938987712908247 0.629328328370365 0.999999999529632 GO:0001848 complement binding 2/1563 25/18639 0.08 0.954011516314779 0.632002772454526 0.999999999529632 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/1563 25/18639 0.08 0.954011516314779 0.632002772454526 0.999999999529632 GO:0017025 TBP-class protein binding 2/1563 25/18639 0.08 0.954011516314779 0.632002772454526 0.999999999529632 GO:0101005 deubiquitinase activity 9/1563 115/18639 0.0782608695652174 0.933272135525328 0.634968505053963 0.999999999529632 GO:0051020 GTPase binding 25/1563 315/18639 0.0793650793650794 0.946439996344027 0.643894526869919 0.999999999529632 GO:0030159 signaling receptor complex adaptor activity 4/1563 52/18639 0.0769230769230769 0.917318765687288 0.64450290074733 0.999999999529632 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0003995 acyl-CoA dehydrogenase activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0004000 adenosine deaminase activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0004032 aldose reductase (NADPH) activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0004126 cytidine deaminase activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0004300 enoyl-CoA hydratase activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0004526 ribonuclease P activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0004875 complement receptor activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0005025 transforming growth factor beta receptor activity, type I 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0005026 transforming growth factor beta receptor activity, type II 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0005095 GTPase inhibitor activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0005165 neurotrophin receptor binding 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0005527 macrolide binding 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0008603 cAMP-dependent protein kinase regulator activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0015132 prostaglandin transmembrane transporter activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0016208 AMP binding 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0016273 arginine N-methyltransferase activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0016274 protein-arginine N-methyltransferase activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0016361 activin receptor activity, type I 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0016362 activin receptor activity, type II 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0016840 carbon-nitrogen lyase activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0017002 activin receptor activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0034452 dynactin binding 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0035197 siRNA binding 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0035251 UDP-glucosyltransferase activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0035497 cAMP response element binding 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0097677 STAT family protein binding 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:1990459 transferrin receptor binding 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:1990817 poly(A) RNA polymerase activity 1/1563 12/18639 0.0833333333333333 0.993761996161228 0.650520558282802 0.999999999529632 GO:0005160 transforming growth factor beta receptor binding 2/1563 26/18639 0.0769230769230769 0.917318765687288 0.653501513256896 0.999999999529632 GO:0015145 monosaccharide transmembrane transporter activity 2/1563 26/18639 0.0769230769230769 0.917318765687288 0.653501513256896 0.999999999529632 GO:0015216 purine nucleotide transmembrane transporter activity 2/1563 26/18639 0.0769230769230769 0.917318765687288 0.653501513256896 0.999999999529632 GO:0050750 low-density lipoprotein particle receptor binding 2/1563 26/18639 0.0769230769230769 0.917318765687288 0.653501513256896 0.999999999529632 GO:0070412 R-SMAD binding 2/1563 26/18639 0.0769230769230769 0.917318765687288 0.653501513256896 0.999999999529632 GO:0033293 monocarboxylic acid binding 6/1563 79/18639 0.0759493670886076 0.905707135741879 0.659382154790006 0.999999999529632 GO:0038064 collagen receptor activity 4/1563 53/18639 0.0754716981132075 0.900010864447905 0.65947501432276 0.999999999529632 GO:0051018 protein kinase A binding 4/1563 53/18639 0.0754716981132075 0.900010864447905 0.65947501432276 0.999999999529632 GO:1901505 carbohydrate derivative transmembrane transporter activity 4/1563 53/18639 0.0754716981132075 0.900010864447905 0.65947501432276 0.999999999529632 GO:0004177 aminopeptidase activity 3/1563 40/18639 0.075 0.894385796545106 0.663292137393332 0.999999999529632 GO:0030331 nuclear estrogen receptor binding 3/1563 40/18639 0.075 0.894385796545106 0.663292137393332 0.999999999529632 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/1563 40/18639 0.075 0.894385796545106 0.663292137393332 0.999999999529632 GO:0061791 GTPase motor activity 3/1563 40/18639 0.075 0.894385796545106 0.663292137393332 0.999999999529632 GO:1990606 membrane scission GTPase motor activity 3/1563 40/18639 0.075 0.894385796545106 0.663292137393332 0.999999999529632 GO:0016500 protein-hormone receptor activity 5/1563 67/18639 0.0746268656716418 0.889936115965279 0.671774880081319 0.999999999529632 GO:0050840 extracellular matrix binding 5/1563 67/18639 0.0746268656716418 0.889936115965279 0.671774880081319 0.999999999529632 GO:0051213 dioxygenase activity 7/1563 93/18639 0.0752688172043011 0.89759148040369 0.672135649905821 0.999999999529632 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/1563 27/18639 0.0740740740740741 0.883343996587759 0.673985067186327 0.999999999529632 GO:0035255 ionotropic glutamate receptor binding 2/1563 27/18639 0.0740740740740741 0.883343996587759 0.673985067186327 0.999999999529632 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2/1563 27/18639 0.0740740740740741 0.883343996587759 0.673985067186327 0.999999999529632 GO:0004812 aminoacyl-tRNA ligase activity 3/1563 41/18639 0.0731707317073171 0.872571508824493 0.679800792990413 0.999999999529632 GO:0016875 ligase activity, forming carbon-oxygen bonds 3/1563 41/18639 0.0731707317073171 0.872571508824493 0.679800792990413 0.999999999529632 GO:0042169 SH2 domain binding 3/1563 41/18639 0.0731707317073171 0.872571508824493 0.679800792990413 0.999999999529632 GO:0042287 MHC protein binding 3/1563 41/18639 0.0731707317073171 0.872571508824493 0.679800792990413 0.999999999529632 GO:0140828 metal cation:monoatomic cation antiporter activity 3/1563 41/18639 0.0731707317073171 0.872571508824493 0.679800792990413 0.999999999529632 GO:0002161 aminoacyl-tRNA editing activity 1/1563 13/18639 0.0769230769230769 0.917318765687288 0.679845536400802 0.999999999529632 GO:0004535 poly(A)-specific ribonuclease activity 1/1563 13/18639 0.0769230769230769 0.917318765687288 0.679845536400802 0.999999999529632 GO:0005035 death receptor activity 1/1563 13/18639 0.0769230769230769 0.917318765687288 0.679845536400802 0.999999999529632 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/1563 13/18639 0.0769230769230769 0.917318765687288 0.679845536400802 0.999999999529632 GO:0008035 high-density lipoprotein particle binding 1/1563 13/18639 0.0769230769230769 0.917318765687288 0.679845536400802 0.999999999529632 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1563 13/18639 0.0769230769230769 0.917318765687288 0.679845536400802 0.999999999529632 GO:0031994 insulin-like growth factor I binding 1/1563 13/18639 0.0769230769230769 0.917318765687288 0.679845536400802 0.999999999529632 GO:0046975 histone H3K36 methyltransferase activity 1/1563 13/18639 0.0769230769230769 0.917318765687288 0.679845536400802 0.999999999529632 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/1563 13/18639 0.0769230769230769 0.917318765687288 0.679845536400802 0.999999999529632 GO:0070123 transforming growth factor beta receptor activity, type III 1/1563 13/18639 0.0769230769230769 0.917318765687288 0.679845536400802 0.999999999529632 GO:0071714 icosanoid transmembrane transporter activity 1/1563 13/18639 0.0769230769230769 0.917318765687288 0.679845536400802 0.999999999529632 GO:0071837 HMG box domain binding 1/1563 13/18639 0.0769230769230769 0.917318765687288 0.679845536400802 0.999999999529632 GO:0140333 glycerophospholipid flippase activity 1/1563 13/18639 0.0769230769230769 0.917318765687288 0.679845536400802 0.999999999529632 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/1563 13/18639 0.0769230769230769 0.917318765687288 0.679845536400802 0.999999999529632 GO:0008237 metallopeptidase activity 14/1563 184/18639 0.0760869565217391 0.907347909538513 0.687336731456416 0.999999999529632 GO:0061135 endopeptidase regulator activity 14/1563 184/18639 0.0760869565217391 0.907347909538513 0.687336731456416 0.999999999529632 GO:0035173 histone kinase activity 28/1563 360/18639 0.0777777777777778 0.927511196417147 0.690430550290706 0.999999999529632 GO:0008201 heparin binding 13/1563 172/18639 0.0755813953488372 0.901319019774137 0.69277349308522 0.999999999529632 GO:0016791 phosphatase activity 21/1563 273/18639 0.0769230769230769 0.917318765687288 0.693036145502126 0.999999999529632 GO:0051019 mitogen-activated protein kinase binding 2/1563 28/18639 0.0714285714285714 0.851795996709624 0.693472406015225 0.999999999529632 GO:0051119 sugar transmembrane transporter activity 2/1563 28/18639 0.0714285714285714 0.851795996709624 0.693472406015225 0.999999999529632 GO:0051537 2 iron, 2 sulfur cluster binding 2/1563 28/18639 0.0714285714285714 0.851795996709624 0.693472406015225 0.999999999529632 GO:1901681 sulfur compound binding 21/1563 275/18639 0.0763636363636364 0.910647356482289 0.705603957876309 0.999999999529632 GO:0004705 JUN kinase activity 1/1563 14/18639 0.0714285714285714 0.851795996709624 0.706711284634752 0.999999999529632 GO:0005545 1-phosphatidylinositol binding 1/1563 14/18639 0.0714285714285714 0.851795996709624 0.706711284634752 0.999999999529632 GO:0008474 palmitoyl-(protein) hydrolase activity 1/1563 14/18639 0.0714285714285714 0.851795996709624 0.706711284634752 0.999999999529632 GO:0008494 translation activator activity 1/1563 14/18639 0.0714285714285714 0.851795996709624 0.706711284634752 0.999999999529632 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/1563 14/18639 0.0714285714285714 0.851795996709624 0.706711284634752 0.999999999529632 GO:0032454 histone H3K9 demethylase activity 1/1563 14/18639 0.0714285714285714 0.851795996709624 0.706711284634752 0.999999999529632 GO:0034236 protein kinase A catalytic subunit binding 1/1563 14/18639 0.0714285714285714 0.851795996709624 0.706711284634752 0.999999999529632 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/1563 14/18639 0.0714285714285714 0.851795996709624 0.706711284634752 0.999999999529632 GO:0046030 inositol trisphosphate phosphatase activity 1/1563 14/18639 0.0714285714285714 0.851795996709624 0.706711284634752 0.999999999529632 GO:0098599 palmitoyl hydrolase activity 1/1563 14/18639 0.0714285714285714 0.851795996709624 0.706711284634752 0.999999999529632 GO:0098821 BMP receptor activity 1/1563 14/18639 0.0714285714285714 0.851795996709624 0.706711284634752 0.999999999529632 GO:1901474 azole transmembrane transporter activity 1/1563 14/18639 0.0714285714285714 0.851795996709624 0.706711284634752 0.999999999529632 GO:1901612 cardiolipin binding 1/1563 14/18639 0.0714285714285714 0.851795996709624 0.706711284634752 0.999999999529632 GO:0008028 monocarboxylic acid transmembrane transporter activity 5/1563 70/18639 0.0714285714285714 0.851795996709624 0.709090295733432 0.999999999529632 GO:0004629 phospholipase C activity 2/1563 29/18639 0.0689655172413793 0.822423720961017 0.711986457953675 0.999999999529632 GO:0010484 histone H3 acetyltransferase activity 2/1563 29/18639 0.0689655172413793 0.822423720961017 0.711986457953675 0.999999999529632 GO:0035250 UDP-galactosyltransferase activity 2/1563 29/18639 0.0689655172413793 0.822423720961017 0.711986457953675 0.999999999529632 GO:0051861 glycolipid binding 2/1563 29/18639 0.0689655172413793 0.822423720961017 0.711986457953675 0.999999999529632 GO:0002020 protease binding 10/1563 136/18639 0.0735294117647059 0.87684882014226 0.713205125736315 0.999999999529632 GO:0015932 nucleobase-containing compound transmembrane transporter activity 4/1563 57/18639 0.0701754385964912 0.836852207293666 0.715010305930952 0.999999999529632 GO:0042626 ATPase-coupled transmembrane transporter activity 7/1563 98/18639 0.0714285714285714 0.851795996709624 0.724410234293106 0.999999999529632 GO:0001223 transcription coactivator binding 3/1563 44/18639 0.0681818181818182 0.813077996859187 0.725688875318793 0.999999999529632 GO:0043014 alpha-tubulin binding 3/1563 44/18639 0.0681818181818182 0.813077996859187 0.725688875318793 0.999999999529632 GO:0008106 alcohol dehydrogenase (NADP+) activity 2/1563 30/18639 0.0666666666666667 0.795009596928983 0.729553311552855 0.999999999529632 GO:0015215 nucleotide transmembrane transporter activity 2/1563 30/18639 0.0666666666666667 0.795009596928983 0.729553311552855 0.999999999529632 GO:0031210 phosphatidylcholine binding 2/1563 30/18639 0.0666666666666667 0.795009596928983 0.729553311552855 0.999999999529632 GO:0051721 protein phosphatase 2A binding 2/1563 30/18639 0.0666666666666667 0.795009596928983 0.729553311552855 0.999999999529632 GO:0004467 long-chain fatty acid-CoA ligase activity 1/1563 15/18639 0.0666666666666667 0.795009596928983 0.731323916157752 0.999999999529632 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1563 15/18639 0.0666666666666667 0.795009596928983 0.731323916157752 0.999999999529632 GO:0004953 icosanoid receptor activity 1/1563 15/18639 0.0666666666666667 0.795009596928983 0.731323916157752 0.999999999529632 GO:0008242 omega peptidase activity 1/1563 15/18639 0.0666666666666667 0.795009596928983 0.731323916157752 0.999999999529632 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1563 15/18639 0.0666666666666667 0.795009596928983 0.731323916157752 0.999999999529632 GO:0031005 filamin binding 1/1563 15/18639 0.0666666666666667 0.795009596928983 0.731323916157752 0.999999999529632 GO:0048531 beta-1,3-galactosyltransferase activity 1/1563 15/18639 0.0666666666666667 0.795009596928983 0.731323916157752 0.999999999529632 GO:0140776 protein-containing complex destabilizing activity 1/1563 15/18639 0.0666666666666667 0.795009596928983 0.731323916157752 0.999999999529632 GO:0141050 histone H3K deacetylase activity 1/1563 15/18639 0.0666666666666667 0.795009596928983 0.731323916157752 0.999999999529632 GO:0141051 histone H4K deacetylase activity 1/1563 15/18639 0.0666666666666667 0.795009596928983 0.731323916157752 0.999999999529632 GO:0016757 glycosyltransferase activity 20/1563 267/18639 0.0749063670411985 0.893269210032565 0.733933193366167 0.999999999529632 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 17/1563 229/18639 0.074235807860262 0.885272695270265 0.735418173140907 0.999999999529632 GO:0030246 carbohydrate binding 21/1563 280/18639 0.075 0.894385796545106 0.735684675516581 0.999999999529632 GO:0005539 glycosaminoglycan binding 18/1563 242/18639 0.0743801652892562 0.88699417839184 0.736830570656577 0.999999999529632 GO:0004715 non-membrane spanning protein tyrosine kinase activity 3/1563 45/18639 0.0666666666666667 0.795009596928983 0.739791660579262 0.999999999529632 GO:0140303 intramembrane lipid transporter activity 3/1563 45/18639 0.0666666666666667 0.795009596928983 0.739791660579262 0.999999999529632 GO:0004879 nuclear receptor activity 4/1563 59/18639 0.0677966101694915 0.808484335859982 0.740158272604371 0.999999999529632 GO:0070888 E-box binding 4/1563 59/18639 0.0677966101694915 0.808484335859982 0.740158272604371 0.999999999529632 GO:0004521 RNA endonuclease activity 5/1563 73/18639 0.0684931506849315 0.816790681776352 0.743321209582266 0.999999999529632 GO:0005164 tumor necrosis factor receptor binding 2/1563 31/18639 0.0645161290322581 0.769364126060306 0.746201525162445 0.999999999529632 GO:0047499 calcium-independent phospholipase A2 activity 2/1563 31/18639 0.0645161290322581 0.769364126060306 0.746201525162445 0.999999999529632 GO:0070325 lipoprotein particle receptor binding 2/1563 31/18639 0.0645161290322581 0.769364126060306 0.746201525162445 0.999999999529632 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 4/1563 60/18639 0.0666666666666667 0.795009596928983 0.752084825328003 0.999999999529632 GO:0098531 ligand-modulated transcription factor activity 4/1563 60/18639 0.0666666666666667 0.795009596928983 0.752084825328003 0.999999999529632 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 12/1563 167/18639 0.0718562874251497 0.856896571540221 0.752545778272244 0.999999999529632 GO:0004707 MAP kinase activity 1/1563 16/18639 0.0625 0.745321497120921 0.753872279508559 0.999999999529632 GO:0004708 MAP kinase kinase activity 1/1563 16/18639 0.0625 0.745321497120921 0.753872279508559 0.999999999529632 GO:0005024 transforming growth factor beta receptor activity 1/1563 16/18639 0.0625 0.745321497120921 0.753872279508559 0.999999999529632 GO:0005149 interleukin-1 receptor binding 1/1563 16/18639 0.0625 0.745321497120921 0.753872279508559 0.999999999529632 GO:0015562 efflux transmembrane transporter activity 1/1563 16/18639 0.0625 0.745321497120921 0.753872279508559 0.999999999529632 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1563 16/18639 0.0625 0.745321497120921 0.753872279508559 0.999999999529632 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/1563 16/18639 0.0625 0.745321497120921 0.753872279508559 0.999999999529632 GO:0022858 alanine transmembrane transporter activity 1/1563 16/18639 0.0625 0.745321497120921 0.753872279508559 0.999999999529632 GO:0070411 I-SMAD binding 1/1563 16/18639 0.0625 0.745321497120921 0.753872279508559 0.999999999529632 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/1563 16/18639 0.0625 0.745321497120921 0.753872279508559 0.999999999529632 GO:0140327 flippase activity 1/1563 16/18639 0.0625 0.745321497120921 0.753872279508559 0.999999999529632 GO:0017124 SH3 domain binding 8/1563 115/18639 0.0695652173913043 0.829575231578069 0.758295241654285 0.999999999529632 GO:0005516 calmodulin binding 15/1563 207/18639 0.072463768115942 0.864140866227155 0.759332736113386 0.999999999529632 GO:0015171 amino acid transmembrane transporter activity 7/1563 102/18639 0.0686274509803922 0.818392232132776 0.761906437686519 0.999999999529632 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/1563 32/18639 0.0625 0.745321497120921 0.76196152985484 0.999999999529632 GO:0047498 calcium-dependent phospholipase A2 activity 2/1563 32/18639 0.0625 0.745321497120921 0.76196152985484 0.999999999529632 GO:0016836 hydro-lyase activity 4/1563 61/18639 0.0655737704918033 0.781976652717032 0.763585638490357 0.999999999529632 GO:0140359 ABC-type transporter activity 3/1563 47/18639 0.0638297872340425 0.761179401314983 0.76626126149896 0.999999999529632 GO:0030414 peptidase inhibitor activity 12/1563 169/18639 0.0710059171597633 0.846755783711343 0.766641657798578 0.999999999529632 GO:0035402 histone H3T11 kinase activity 18/1563 247/18639 0.0728744939271255 0.869038830651115 0.76680263832634 0.999999999529632 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 6/1563 89/18639 0.0674157303370786 0.803942289029308 0.76707219487824 0.999999999529632 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 6/1563 89/18639 0.0674157303370786 0.803942289029308 0.76707219487824 0.999999999529632 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/1563 17/18639 0.0588235294117647 0.701479056113808 0.774529403877786 0.999999999529632 GO:0004549 tRNA-specific ribonuclease activity 1/1563 17/18639 0.0588235294117647 0.701479056113808 0.774529403877786 0.999999999529632 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/1563 17/18639 0.0588235294117647 0.701479056113808 0.774529403877786 0.999999999529632 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/1563 17/18639 0.0588235294117647 0.701479056113808 0.774529403877786 0.999999999529632 GO:0031489 myosin V binding 1/1563 17/18639 0.0588235294117647 0.701479056113808 0.774529403877786 0.999999999529632 GO:0036041 long-chain fatty acid binding 1/1563 17/18639 0.0588235294117647 0.701479056113808 0.774529403877786 0.999999999529632 GO:0038191 neuropilin binding 1/1563 17/18639 0.0588235294117647 0.701479056113808 0.774529403877786 0.999999999529632 GO:0048038 quinone binding 1/1563 17/18639 0.0588235294117647 0.701479056113808 0.774529403877786 0.999999999529632 GO:0070492 oligosaccharide binding 1/1563 17/18639 0.0588235294117647 0.701479056113808 0.774529403877786 0.999999999529632 GO:0015179 L-amino acid transmembrane transporter activity 4/1563 62/18639 0.0645161290322581 0.769364126060306 0.774666294412468 0.999999999529632 GO:0140793 histone H2AXY142 phosphatase activity 6/1563 90/18639 0.0666666666666667 0.795009596928983 0.77629310328982 0.999999999529632 GO:0019239 deaminase activity 2/1563 33/18639 0.0606060606060606 0.722735997208166 0.776865115011953 0.999999999529632 GO:0019956 chemokine binding 2/1563 33/18639 0.0606060606060606 0.722735997208166 0.776865115011953 0.999999999529632 GO:0071889 14-3-3 protein binding 2/1563 33/18639 0.0606060606060606 0.722735997208166 0.776865115011953 0.999999999529632 GO:0042277 peptide binding 18/1563 249/18639 0.072289156626506 0.86205859907962 0.778131157876658 0.999999999529632 GO:0072341 modified amino acid binding 6/1563 91/18639 0.0659340659340659 0.786273227731961 0.785236887045824 0.999999999529632 GO:0005179 hormone activity 9/1563 132/18639 0.0681818181818182 0.813077996859187 0.78670776275163 0.999999999529632 GO:0141003 histone H2AX kinase activity 26/1563 354/18639 0.0734463276836158 0.875858030514981 0.788597667131218 0.999999999529632 GO:0035254 glutamate receptor binding 3/1563 49/18639 0.0612244897959184 0.730110854322535 0.790494709185096 0.999999999529632 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/1563 18/18639 0.0555555555555556 0.662507997440819 0.793453823474984 0.999999999529632 GO:0004706 JUN kinase kinase kinase activity 1/1563 18/18639 0.0555555555555556 0.662507997440819 0.793453823474984 0.999999999529632 GO:0008525 phosphatidylcholine transporter activity 1/1563 18/18639 0.0555555555555556 0.662507997440819 0.793453823474984 0.999999999529632 GO:0015280 ligand-gated sodium channel activity 1/1563 18/18639 0.0555555555555556 0.662507997440819 0.793453823474984 0.999999999529632 GO:0016854 racemase and epimerase activity 1/1563 18/18639 0.0555555555555556 0.662507997440819 0.793453823474984 0.999999999529632 GO:0017128 phospholipid scramblase activity 1/1563 18/18639 0.0555555555555556 0.662507997440819 0.793453823474984 0.999999999529632 GO:0035615 clathrin adaptor activity 1/1563 18/18639 0.0555555555555556 0.662507997440819 0.793453823474984 0.999999999529632 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/1563 18/18639 0.0555555555555556 0.662507997440819 0.793453823474984 0.999999999529632 GO:1901611 phosphatidylglycerol binding 1/1563 18/18639 0.0555555555555556 0.662507997440819 0.793453823474984 0.999999999529632 GO:0043178 alcohol binding 6/1563 92/18639 0.0652173913043478 0.77772677960444 0.793906228008832 0.999999999529632 GO:0008013 beta-catenin binding 7/1563 106/18639 0.0660377358490566 0.787509506391917 0.795562357688921 0.999999999529632 GO:0008234 cysteine-type peptidase activity 13/1563 187/18639 0.0695187165775401 0.829020702679955 0.79775496875474 0.999999999529632 GO:0004866 endopeptidase inhibitor activity 11/1563 161/18639 0.0683229813664596 0.814761388157032 0.801585763860363 0.999999999529632 GO:0005178 integrin binding 11/1563 161/18639 0.0683229813664596 0.814761388157032 0.801585763860363 0.999999999529632 GO:0140996 histone H3 kinase activity 26/1563 357/18639 0.0728291316526611 0.868497878998048 0.802017302480369 0.999999999529632 GO:0004623 phospholipase A2 activity 2/1563 35/18639 0.0571428571428571 0.681436797367699 0.804234391780668 0.999999999529632 GO:0015297 antiporter activity 9/1563 135/18639 0.0666666666666667 0.795009596928983 0.807941696330665 0.999999999529632 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/1563 19/18639 0.0526315789473684 0.62763915547025 0.810790791087282 0.999999999529632 GO:0005520 insulin-like growth factor binding 1/1563 19/18639 0.0526315789473684 0.62763915547025 0.810790791087282 0.999999999529632 GO:0022840 leak channel activity 1/1563 19/18639 0.0526315789473684 0.62763915547025 0.810790791087282 0.999999999529632 GO:0022842 narrow pore channel activity 1/1563 19/18639 0.0526315789473684 0.62763915547025 0.810790791087282 0.999999999529632 GO:0034987 immunoglobulin receptor binding 1/1563 19/18639 0.0526315789473684 0.62763915547025 0.810790791087282 0.999999999529632 GO:0043395 heparan sulfate proteoglycan binding 1/1563 19/18639 0.0526315789473684 0.62763915547025 0.810790791087282 0.999999999529632 GO:0046527 glucosyltransferase activity 1/1563 19/18639 0.0526315789473684 0.62763915547025 0.810790791087282 0.999999999529632 GO:0004843 cysteine-type deubiquitinase activity 7/1563 108/18639 0.0648148148148148 0.772925997014289 0.810980648840347 0.999999999529632 GO:0005496 steroid binding 7/1563 108/18639 0.0648148148148148 0.772925997014289 0.810980648840347 0.999999999529632 GO:0008235 metalloexopeptidase activity 4/1563 66/18639 0.0606060606060606 0.722735997208166 0.814925577325877 0.999999999529632 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 17/1563 243/18639 0.0699588477366255 0.834269330110661 0.815460058705309 0.999999999529632 GO:0004033 aldo-keto reductase (NADPH) activity 2/1563 36/18639 0.0555555555555556 0.662507997440819 0.816766795382023 0.999999999529632 GO:0004867 serine-type endopeptidase inhibitor activity 6/1563 95/18639 0.0631578947368421 0.753166986564299 0.818300076392521 0.999999999529632 GO:0031267 small GTPase binding 20/1563 283/18639 0.0706713780918728 0.842766357168533 0.818694116416233 0.999999999529632 GO:0008168 methyltransferase activity 14/1563 204/18639 0.0686274509803922 0.818392232132776 0.818992028386483 0.999999999529632 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 3/1563 52/18639 0.0576923076923077 0.687989074265466 0.822891794995091 0.999999999529632 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/1563 67/18639 0.0597014925373134 0.711948892772223 0.824014510484262 0.999999999529632 GO:0004676 3-phosphoinositide-dependent protein kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:0004711 ribosomal protein S6 kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:0035175 histone H3S10 kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:0035979 histone H2AXS139 kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:0044022 histone H3S28 kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:0044023 histone H4S1 kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:0044024 histone H2AS1 kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:0044025 histone H2BS14 kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:0072354 histone H3T3 kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:0072371 histone H2AS121 kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:0072518 Rho-dependent protein serine/threonine kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:0140823 histone H2BS36 kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:0140855 histone H3S57 kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:0140995 histone H2A kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:0140997 histone H4 kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:0140998 histone H2B kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:1990244 histone H2AT120 kinase activity 17/1563 245/18639 0.0693877551020408 0.827458968232206 0.825301092912178 0.999999999529632 GO:0004222 metalloendopeptidase activity 7/1563 110/18639 0.0636363636363636 0.758872797068574 0.825485429413296 0.999999999529632 GO:0015464 acetylcholine receptor activity 1/1563 20/18639 0.05 0.596257197696737 0.826673390095369 0.999999999529632 GO:0016004 phospholipase activator activity 1/1563 20/18639 0.05 0.596257197696737 0.826673390095369 0.999999999529632 GO:0030627 pre-mRNA 5'-splice site binding 1/1563 20/18639 0.05 0.596257197696737 0.826673390095369 0.999999999529632 GO:0140939 histone H4 methyltransferase activity 1/1563 20/18639 0.05 0.596257197696737 0.826673390095369 0.999999999529632 GO:0043394 proteoglycan binding 2/1563 37/18639 0.0540540540540541 0.644602375888364 0.828575612697623 0.999999999529632 GO:0004677 DNA-dependent protein kinase activity 17/1563 246/18639 0.0691056910569106 0.824095313889799 0.830074808489847 0.999999999529632 GO:0140857 histone H3T45 kinase activity 17/1563 246/18639 0.0691056910569106 0.824095313889799 0.830074808489847 0.999999999529632 GO:0005544 calcium-dependent phospholipid binding 3/1563 53/18639 0.0566037735849057 0.675008148335929 0.832696801835431 0.999999999529632 GO:0005548 phospholipid transporter activity 4/1563 68/18639 0.0588235294117647 0.701479056113808 0.832730766245775 0.999999999529632 GO:0033218 amide binding 17/1563 247/18639 0.0688259109311741 0.820758895614942 0.834751447154106 0.999999999529632 GO:0035403 histone H3T6 kinase activity 17/1563 247/18639 0.0688259109311741 0.820758895614942 0.834751447154106 0.999999999529632 GO:0004679 AMP-activated protein kinase activity 17/1563 248/18639 0.0685483870967742 0.817449383939075 0.839331670197089 0.999999999529632 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 12/1563 181/18639 0.0662983425414365 0.790617278713905 0.839495557387764 0.999999999529632 GO:0004725 protein tyrosine phosphatase activity 6/1563 98/18639 0.0612244897959184 0.730110854322535 0.840354292543704 0.999999999529632 GO:0016279 protein-lysine N-methyltransferase activity 4/1563 69/18639 0.0579710144927536 0.691312692981724 0.841083826331194 0.999999999529632 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/1563 21/18639 0.0476190476190476 0.567863997806416 0.841223553438242 0.999999999529632 GO:0010314 phosphatidylinositol-5-phosphate binding 1/1563 21/18639 0.0476190476190476 0.567863997806416 0.841223553438242 0.999999999529632 GO:0061891 calcium ion sensor activity 1/1563 21/18639 0.0476190476190476 0.567863997806416 0.841223553438242 0.999999999529632 GO:0140312 cargo adaptor activity 1/1563 21/18639 0.0476190476190476 0.567863997806416 0.841223553438242 0.999999999529632 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/1563 54/18639 0.0555555555555556 0.662507997440819 0.842031070368327 0.999999999529632 GO:0016278 lysine N-methyltransferase activity 4/1563 70/18639 0.0571428571428571 0.681436797367699 0.84908343424621 0.999999999529632 GO:0016758 hexosyltransferase activity 13/1563 197/18639 0.065989847715736 0.786938433508384 0.851708960610343 0.999999999529632 GO:0004407 histone deacetylase activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0005243 gap junction channel activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0008093 cytoskeletal anchor activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0016881 acid-amino acid ligase activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0032931 histone H3K56 acetyltransferase activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0033558 protein lysine deacetylase activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0033691 sialic acid binding 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0043992 histone H3K9 acetyltransferase activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0043993 histone H3K18 acetyltransferase activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0043994 histone H3K23 acetyltransferase activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0043999 histone H2AK5 acetyltransferase activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0044012 histone H2AK9 acetyltransferase activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0044014 histone H2BK5 acetyltransferase activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0044015 histone H2BK12 acetyltransferase activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0044016 histone H3K4 acetyltransferase activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0044017 histone H3K27 acetyltransferase activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0044018 histone H3K36 acetyltransferase activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0046972 histone H4K16 acetyltransferase activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0140784 metal ion sensor activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0140908 histone H3K122 acetyltransferase activity 1/1563 22/18639 0.0454545454545455 0.542051997906125 0.854552997308476 0.999999999529632 GO:0170055 lipid transmembrane transporter activity 3/1563 56/18639 0.0535714285714286 0.638846997532218 0.859351914327032 0.999999999529632 GO:0015144 carbohydrate transmembrane transporter activity 2/1563 40/18639 0.05 0.596257197696737 0.859989437489491 0.999999999529632 GO:0071855 neuropeptide receptor binding 2/1563 40/18639 0.05 0.596257197696737 0.859989437489491 0.999999999529632 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 8/1563 130/18639 0.0615384615384615 0.73385501254983 0.86248178550327 0.999999999529632 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/1563 23/18639 0.0434782608695652 0.518484519736293 0.866764076709392 0.999999999529632 GO:0005158 insulin receptor binding 1/1563 23/18639 0.0434782608695652 0.518484519736293 0.866764076709392 0.999999999529632 GO:0005212 structural constituent of eye lens 1/1563 23/18639 0.0434782608695652 0.518484519736293 0.866764076709392 0.999999999529632 GO:0016493 C-C chemokine receptor activity 1/1563 23/18639 0.0434782608695652 0.518484519736293 0.866764076709392 0.999999999529632 GO:0042171 lysophosphatidic acid acyltransferase activity 1/1563 23/18639 0.0434782608695652 0.518484519736293 0.866764076709392 0.999999999529632 GO:0044013 histone H2B acetyltransferase activity 1/1563 23/18639 0.0434782608695652 0.518484519736293 0.866764076709392 0.999999999529632 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/1563 23/18639 0.0434782608695652 0.518484519736293 0.866764076709392 0.999999999529632 GO:0071617 lysophospholipid acyltransferase activity 1/1563 23/18639 0.0434782608695652 0.518484519736293 0.866764076709392 0.999999999529632 GO:0140103 catalytic activity, acting on a glycoprotein 1/1563 23/18639 0.0434782608695652 0.518484519736293 0.866764076709392 0.999999999529632 GO:1990782 protein tyrosine kinase binding 7/1563 117/18639 0.0598290598290598 0.713470151090113 0.869442236815514 0.999999999529632 GO:0005253 monoatomic anion channel activity 6/1563 103/18639 0.058252427184466 0.694668579840859 0.872250597243542 0.999999999529632 GO:0042578 phosphoric ester hydrolase activity 25/1563 363/18639 0.068870523415978 0.821290905918371 0.873926001001692 0.999999999529632 GO:0001664 G protein-coupled receptor binding 20/1563 297/18639 0.0673400673400673 0.803039996897962 0.875255841348089 0.999999999529632 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/1563 24/18639 0.0416666666666667 0.496880998080614 0.877950569409393 0.999999999529632 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/1563 24/18639 0.0416666666666667 0.496880998080614 0.877950569409393 0.999999999529632 GO:0005315 phosphate transmembrane transporter activity 1/1563 24/18639 0.0416666666666667 0.496880998080614 0.877950569409393 0.999999999529632 GO:0019957 C-C chemokine binding 1/1563 24/18639 0.0416666666666667 0.496880998080614 0.877950569409393 0.999999999529632 GO:0030552 cAMP binding 1/1563 24/18639 0.0416666666666667 0.496880998080614 0.877950569409393 0.999999999529632 GO:0035035 histone acetyltransferase binding 1/1563 24/18639 0.0416666666666667 0.496880998080614 0.877950569409393 0.999999999529632 GO:0043998 histone H2A acetyltransferase activity 1/1563 24/18639 0.0416666666666667 0.496880998080614 0.877950569409393 0.999999999529632 GO:0060229 lipase activator activity 1/1563 24/18639 0.0416666666666667 0.496880998080614 0.877950569409393 0.999999999529632 GO:0004252 serine-type endopeptidase activity 11/1563 176/18639 0.0625 0.745321497120921 0.881260620226666 0.999999999529632 GO:0008083 growth factor activity 10/1563 162/18639 0.0617283950617284 0.736119997156465 0.881290488557113 0.999999999529632 GO:0001786 phosphatidylserine binding 3/1563 59/18639 0.0508474576271186 0.606363251894987 0.882206573633265 0.999999999529632 GO:0015459 potassium channel regulator activity 3/1563 59/18639 0.0508474576271186 0.606363251894987 0.882206573633265 0.999999999529632 GO:0015291 secondary active transmembrane transporter activity 19/1563 287/18639 0.0662020905923345 0.789469460365018 0.886874090353069 0.999999999529632 GO:0000030 mannosyltransferase activity 1/1563 25/18639 0.04 0.47700575815739 0.888198394282513 0.999999999529632 GO:0003707 nuclear steroid receptor activity 1/1563 25/18639 0.04 0.47700575815739 0.888198394282513 0.999999999529632 GO:0004709 MAP kinase kinase kinase activity 1/1563 25/18639 0.04 0.47700575815739 0.888198394282513 0.999999999529632 GO:0015645 fatty acid ligase activity 1/1563 25/18639 0.04 0.47700575815739 0.888198394282513 0.999999999529632 GO:0015662 P-type ion transporter activity 1/1563 25/18639 0.04 0.47700575815739 0.888198394282513 0.999999999529632 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/1563 25/18639 0.04 0.47700575815739 0.888198394282513 0.999999999529632 GO:0019707 protein-cysteine S-acyltransferase activity 1/1563 25/18639 0.04 0.47700575815739 0.888198394282513 0.999999999529632 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/1563 25/18639 0.04 0.47700575815739 0.888198394282513 0.999999999529632 GO:0120515 fatty acid-CoA ligase activity 1/1563 25/18639 0.04 0.47700575815739 0.888198394282513 0.999999999529632 GO:0140358 P-type transmembrane transporter activity 1/1563 25/18639 0.04 0.47700575815739 0.888198394282513 0.999999999529632 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/1563 44/18639 0.0454545454545455 0.542051997906125 0.893684578021172 0.999999999529632 GO:0019905 syntaxin binding 3/1563 61/18639 0.0491803278688525 0.586482489537774 0.895544885747391 0.999999999529632 GO:0001637 G protein-coupled chemoattractant receptor activity 1/1563 26/18639 0.0384615384615385 0.458659382843644 0.897586269523537 0.999999999529632 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/1563 26/18639 0.0384615384615385 0.458659382843644 0.897586269523537 0.999999999529632 GO:0004435 phosphatidylinositol phospholipase C activity 1/1563 26/18639 0.0384615384615385 0.458659382843644 0.897586269523537 0.999999999529632 GO:0004950 chemokine receptor activity 1/1563 26/18639 0.0384615384615385 0.458659382843644 0.897586269523537 0.999999999529632 GO:0005112 Notch binding 1/1563 26/18639 0.0384615384615385 0.458659382843644 0.897586269523537 0.999999999529632 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/1563 26/18639 0.0384615384615385 0.458659382843644 0.897586269523537 0.999999999529632 GO:0008157 protein phosphatase 1 binding 1/1563 26/18639 0.0384615384615385 0.458659382843644 0.897586269523537 0.999999999529632 GO:0008198 ferrous iron binding 1/1563 26/18639 0.0384615384615385 0.458659382843644 0.897586269523537 0.999999999529632 GO:0034237 protein kinase A regulatory subunit binding 1/1563 26/18639 0.0384615384615385 0.458659382843644 0.897586269523537 0.999999999529632 GO:0043548 phosphatidylinositol 3-kinase binding 1/1563 26/18639 0.0384615384615385 0.458659382843644 0.897586269523537 0.999999999529632 GO:0052742 phosphatidylinositol kinase activity 1/1563 26/18639 0.0384615384615385 0.458659382843644 0.897586269523537 0.999999999529632 GO:0120014 phospholipid transfer activity 1/1563 26/18639 0.0384615384615385 0.458659382843644 0.897586269523537 0.999999999529632 GO:0042605 peptide antigen binding 2/1563 45/18639 0.0444444444444444 0.530006397952655 0.90084238813475 0.999999999529632 GO:0070851 growth factor receptor binding 8/1563 139/18639 0.0575539568345324 0.686339220370345 0.905198118553254 0.999999999529632 GO:0016247 channel regulator activity 10/1563 168/18639 0.0595238095238095 0.70982999725802 0.905691474065443 0.999999999529632 GO:0005044 scavenger receptor activity 1/1563 27/18639 0.037037037037037 0.441671998293879 0.906186315767276 0.999999999529632 GO:0008395 steroid hydroxylase activity 1/1563 27/18639 0.037037037037037 0.441671998293879 0.906186315767276 0.999999999529632 GO:0016405 CoA-ligase activity 1/1563 27/18639 0.037037037037037 0.441671998293879 0.906186315767276 0.999999999529632 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/1563 27/18639 0.037037037037037 0.441671998293879 0.906186315767276 0.999999999529632 GO:1901682 sulfur compound transmembrane transporter activity 3/1563 63/18639 0.0476190476190476 0.567863997806416 0.90750915798744 0.999999999529632 GO:1902936 phosphatidylinositol bisphosphate binding 6/1563 111/18639 0.0540540540540541 0.644602375888364 0.912114490804555 0.999999999529632 GO:0141108 transporter regulator activity 10/1563 170/18639 0.0588235294117647 0.701479056113808 0.912829865693562 0.999999999529632 GO:0036408 histone H3K14 acetyltransferase activity 1/1563 28/18639 0.0357142857142857 0.425897998354812 0.914064608721056 0.999999999529632 GO:0051959 dynein light intermediate chain binding 1/1563 28/18639 0.0357142857142857 0.425897998354812 0.914064608721056 0.999999999529632 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/1563 28/18639 0.0357142857142857 0.425897998354812 0.914064608721056 0.999999999529632 GO:0141052 histone H3 demethylase activity 1/1563 28/18639 0.0357142857142857 0.425897998354812 0.914064608721056 0.999999999529632 GO:1901981 phosphatidylinositol phosphate binding 11/1563 185/18639 0.0594594594594595 0.709062613477201 0.915081317781683 0.999999999529632 GO:0030971 receptor tyrosine kinase binding 4/1563 81/18639 0.0493827160493827 0.588895997725172 0.916646246576322 0.999999999529632 GO:0038024 cargo receptor activity 3/1563 65/18639 0.0461538461538462 0.550391259412373 0.918217648029963 0.999999999529632 GO:0004181 metallocarboxypeptidase activity 1/1563 29/18639 0.0344827586206897 0.411211860480508 0.921281685534177 0.999999999529632 GO:0016417 S-acyltransferase activity 1/1563 29/18639 0.0344827586206897 0.411211860480508 0.921281685534177 0.999999999529632 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/1563 29/18639 0.0344827586206897 0.411211860480508 0.921281685534177 0.999999999529632 GO:0008170 N-methyltransferase activity 5/1563 98/18639 0.0510204081632653 0.608425711935446 0.921897788561267 0.999999999529632 GO:0035591 signaling adaptor activity 7/1563 129/18639 0.0542635658914729 0.647100834709637 0.923400670208903 0.999999999529632 GO:0046943 carboxylic acid transmembrane transporter activity 11/1563 188/18639 0.0585106382978723 0.697747784538735 0.924379836026903 0.999999999529632 GO:0001540 amyloid-beta binding 4/1563 83/18639 0.0481927710843374 0.574705732719747 0.925515616110444 0.999999999529632 GO:0030165 PDZ domain binding 4/1563 83/18639 0.0481927710843374 0.574705732719747 0.925515616110444 0.999999999529632 GO:0005342 organic acid transmembrane transporter activity 11/1563 189/18639 0.0582010582010582 0.694055997318953 0.927280333727032 0.999999999529632 GO:0099106 ion channel regulator activity 9/1563 160/18639 0.05625 0.670789347408829 0.927614252413606 0.999999999529632 GO:0031624 ubiquitin conjugating enzyme binding 1/1563 30/18639 0.0333333333333333 0.397504798464491 0.927893008774912 0.999999999529632 GO:0032452 histone demethylase activity 1/1563 30/18639 0.0333333333333333 0.397504798464491 0.927893008774912 0.999999999529632 GO:0043995 histone H4K5 acetyltransferase activity 1/1563 30/18639 0.0333333333333333 0.397504798464491 0.927893008774912 0.999999999529632 GO:0043996 histone H4K8 acetyltransferase activity 1/1563 30/18639 0.0333333333333333 0.397504798464491 0.927893008774912 0.999999999529632 GO:0043997 histone H4K12 acetyltransferase activity 1/1563 30/18639 0.0333333333333333 0.397504798464491 0.927893008774912 0.999999999529632 GO:0070566 adenylyltransferase activity 1/1563 30/18639 0.0333333333333333 0.397504798464491 0.927893008774912 0.999999999529632 GO:0015293 symporter activity 8/1563 146/18639 0.0547945205479452 0.653432545421082 0.930112746181213 0.999999999529632 GO:0015605 organophosphate ester transmembrane transporter activity 2/1563 50/18639 0.04 0.47700575815739 0.930344833921607 0.999999999529632 GO:0032813 tumor necrosis factor receptor superfamily binding 2/1563 50/18639 0.04 0.47700575815739 0.930344833921607 0.999999999529632 GO:0048020 CCR chemokine receptor binding 2/1563 50/18639 0.04 0.47700575815739 0.930344833921607 0.999999999529632 GO:0015294 solute:monoatomic cation symporter activity 6/1563 116/18639 0.0517241379310345 0.616817790720762 0.931128354867495 0.999999999529632 GO:0005184 neuropeptide hormone activity 1/1563 31/18639 0.032258064516129 0.384682063030153 0.933949391561994 0.999999999529632 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/1563 31/18639 0.032258064516129 0.384682063030153 0.933949391561994 0.999999999529632 GO:0016411 acylglycerol O-acyltransferase activity 1/1563 31/18639 0.032258064516129 0.384682063030153 0.933949391561994 0.999999999529632 GO:0016878 acid-thiol ligase activity 1/1563 31/18639 0.032258064516129 0.384682063030153 0.933949391561994 0.999999999529632 GO:0017147 Wnt-protein binding 1/1563 31/18639 0.032258064516129 0.384682063030153 0.933949391561994 0.999999999529632 GO:0070273 phosphatidylinositol-4-phosphate binding 1/1563 31/18639 0.032258064516129 0.384682063030153 0.933949391561994 0.999999999529632 GO:0140457 protein demethylase activity 1/1563 31/18639 0.032258064516129 0.384682063030153 0.933949391561994 0.999999999529632 GO:0016597 amino acid binding 2/1563 51/18639 0.0392156862745098 0.467652704075872 0.935150740284968 0.999999999529632 GO:0030544 Hsp70 protein binding 2/1563 51/18639 0.0392156862745098 0.467652704075872 0.935150740284968 0.999999999529632 GO:0008238 exopeptidase activity 5/1563 102/18639 0.0490196078431373 0.58456588009484 0.936732289629419 0.999999999529632 GO:0005319 lipid transporter activity 10/1563 178/18639 0.0561797752808989 0.669951907524424 0.936981563035833 0.999999999529632 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/1563 86/18639 0.0465116279069767 0.554657858322546 0.937231145163728 0.999999999529632 GO:0015106 bicarbonate transmembrane transporter activity 1/1563 32/18639 0.03125 0.372660748560461 0.939497387100934 0.999999999529632 GO:0071813 lipoprotein particle binding 1/1563 32/18639 0.03125 0.372660748560461 0.939497387100934 0.999999999529632 GO:0071814 protein-lipid complex binding 1/1563 32/18639 0.03125 0.372660748560461 0.939497387100934 0.999999999529632 GO:0160041 neuropeptide activity 1/1563 32/18639 0.03125 0.372660748560461 0.939497387100934 0.999999999529632 GO:0008236 serine-type peptidase activity 11/1563 194/18639 0.0567010309278351 0.676167956150939 0.940395673907654 0.999999999529632 GO:0008081 phosphoric diester hydrolase activity 4/1563 87/18639 0.0459770114942529 0.548282480640678 0.940747635333612 0.999999999529632 GO:0004175 endopeptidase activity 26/1563 405/18639 0.0641975308641975 0.765564797042724 0.942004689287171 0.999999999529632 GO:0030296 protein tyrosine kinase activator activity 1/1563 33/18639 0.0303030303030303 0.361367998604083 0.944579645603715 0.999999999529632 GO:0008514 organic anion transmembrane transporter activity 16/1563 269/18639 0.0594795539033457 0.709302242613219 0.946992780254484 0.999999999529632 GO:0015020 glucuronosyltransferase activity 1/1563 34/18639 0.0294117647058824 0.350739528056904 0.9492352413213 0.999999999529632 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/1563 34/18639 0.0294117647058824 0.350739528056904 0.9492352413213 0.999999999529632 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/1563 34/18639 0.0294117647058824 0.350739528056904 0.9492352413213 0.999999999529632 GO:0017171 serine hydrolase activity 11/1563 198/18639 0.0555555555555556 0.662507997440819 0.949360722197751 0.999999999529632 GO:0008374 O-acyltransferase activity 2/1563 55/18639 0.0363636363636364 0.4336415983249 0.951404860314873 0.999999999529632 GO:0004620 phospholipase activity 5/1563 109/18639 0.0458715596330275 0.547024952015355 0.956719530598845 0.999999999529632 GO:0004190 aspartic-type endopeptidase activity 1/1563 36/18639 0.0277777777777778 0.331253998720409 0.95740663438466 0.999999999529632 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/1563 36/18639 0.0277777777777778 0.331253998720409 0.95740663438466 0.999999999529632 GO:0016409 palmitoyltransferase activity 1/1563 36/18639 0.0277777777777778 0.331253998720409 0.95740663438466 0.999999999529632 GO:0045505 dynein intermediate chain binding 1/1563 36/18639 0.0277777777777778 0.331253998720409 0.95740663438466 0.999999999529632 GO:0019213 deacetylase activity 1/1563 37/18639 0.027027027027027 0.322301187944182 0.960985273875967 0.999999999529632 GO:0030280 structural constituent of skin epidermis 1/1563 37/18639 0.027027027027027 0.322301187944182 0.960985273875967 0.999999999529632 GO:0030551 cyclic nucleotide binding 1/1563 37/18639 0.027027027027027 0.322301187944182 0.960985273875967 0.999999999529632 GO:0070001 aspartic-type peptidase activity 1/1563 37/18639 0.027027027027027 0.322301187944182 0.960985273875967 0.999999999529632 GO:0005501 retinoid binding 1/1563 38/18639 0.0263157894736842 0.313819577735125 0.964263416921438 0.999999999529632 GO:0019840 isoprenoid binding 1/1563 38/18639 0.0263157894736842 0.313819577735125 0.964263416921438 0.999999999529632 GO:0042887 amide transmembrane transporter activity 1/1563 38/18639 0.0263157894736842 0.313819577735125 0.964263416921438 0.999999999529632 GO:0008194 UDP-glycosyltransferase activity 7/1563 145/18639 0.0482758620689655 0.575696604672712 0.964612590534878 0.999999999529632 GO:0016298 lipase activity 6/1563 130/18639 0.0461538461538462 0.550391259412373 0.966442923501677 0.999999999529632 GO:0016798 hydrolase activity, acting on glycosyl bonds 6/1563 130/18639 0.0461538461538462 0.550391259412373 0.966442923501677 0.999999999529632 GO:0035091 phosphatidylinositol binding 16/1563 284/18639 0.0563380281690141 0.671839095996323 0.969469374320419 0.999999999529632 GO:0032451 demethylase activity 1/1563 40/18639 0.025 0.298128598848369 0.97001696955024 0.999999999529632 GO:0071949 FAD binding 1/1563 40/18639 0.025 0.298128598848369 0.97001696955024 0.999999999529632 GO:0005096 GTPase activator activity 15/1563 271/18639 0.0553505535055351 0.660063318483473 0.9713174398816 0.999999999529632 GO:0001727 lipid kinase activity 1/1563 41/18639 0.024390243902439 0.290857169608164 0.972536646769068 0.999999999529632 GO:0017080 sodium channel regulator activity 1/1563 41/18639 0.024390243902439 0.290857169608164 0.972536646769068 0.999999999529632 GO:0005254 chloride channel activity 3/1563 83/18639 0.036144578313253 0.43102929953981 0.974380697232552 0.999999999529632 GO:0005201 extracellular matrix structural constituent 8/1563 168/18639 0.0476190476190476 0.567863997806416 0.975208324240757 0.999999999529632 GO:0016790 thiolester hydrolase activity 1/1563 44/18639 0.0227272727272727 0.271025998953062 0.978895512119744 0.999999999529632 GO:0030547 signaling receptor inhibitor activity 1/1563 44/18639 0.0227272727272727 0.271025998953062 0.978895512119744 0.999999999529632 GO:0050660 flavin adenine dinucleotide binding 3/1563 86/18639 0.0348837209302326 0.41599339374191 0.979052582421329 0.999999999529632 GO:0140101 catalytic activity, acting on a tRNA 6/1563 139/18639 0.0431654676258993 0.514754415277759 0.979387628144819 0.999999999529632 GO:0008173 RNA methyltransferase activity 2/1563 67/18639 0.0298507462686567 0.355974446386112 0.979977113059947 0.999999999529632 GO:0008009 chemokine activity 1/1563 45/18639 0.0222222222222222 0.265003198976328 0.980669446755767 0.999999999529632 GO:0000149 SNARE binding 4/1563 106/18639 0.0377358490566038 0.450005432223953 0.981165389403828 0.999999999529632 GO:0140223 general transcription initiation factor activity 2/1563 68/18639 0.0294117647058824 0.350739528056904 0.981425823669577 0.999999999529632 GO:0004180 carboxypeptidase activity 1/1563 46/18639 0.0217391304347826 0.259242259868147 0.982294360960388 0.999999999529632 GO:0016782 transferase activity, transferring sulphur-containing groups 2/1563 70/18639 0.0285714285714286 0.34071839868385 0.984024242542054 0.999999999529632 GO:0019955 cytokine binding 6/1563 144/18639 0.0416666666666667 0.496880998080614 0.984395465871341 0.999999999529632 GO:0008188 neuropeptide receptor activity 1/1563 48/18639 0.0208333333333333 0.248440499040307 0.985146123129436 0.999999999529632 GO:0052689 carboxylic ester hydrolase activity 3/1563 92/18639 0.0326086956521739 0.38886338980222 0.986074027712451 0.999999999529632 GO:0042379 chemokine receptor binding 2/1563 72/18639 0.0277777777777778 0.331253998720409 0.986267820656941 0.999999999529632 GO:0008509 monoatomic anion transmembrane transporter activity 6/1563 149/18639 0.0402684563758389 0.48020713908462 0.988245824316875 0.999999999529632 GO:0005272 sodium channel activity 1/1563 51/18639 0.0196078431372549 0.233826352037936 0.988586573192734 0.999999999529632 GO:0005125 cytokine activity 11/1563 234/18639 0.047008547008547 0.560583690142231 0.989842237900866 0.999999999529632 GO:0030695 GTPase regulator activity 28/1563 489/18639 0.0572597137014315 0.68283032865066 0.99027324244294 0.999999999529632 GO:0008146 sulfotransferase activity 1/1563 53/18639 0.0188679245283019 0.225002716111976 0.990425351781527 0.999999999529632 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/1563 53/18639 0.0188679245283019 0.225002716111976 0.990425351781527 0.999999999529632 GO:0017046 peptide hormone binding 1/1563 53/18639 0.0188679245283019 0.225002716111976 0.990425351781527 0.999999999529632 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/1563 53/18639 0.0188679245283019 0.225002716111976 0.990425351781527 0.999999999529632 GO:0060589 nucleoside-triphosphatase regulator activity 28/1563 490/18639 0.0571428571428571 0.681436797367699 0.9906047460024 0.999999999529632 GO:0015370 solute:sodium symporter activity 2/1563 79/18639 0.0253164556962025 0.301902378580626 0.99195121320566 0.999999999529632 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/1563 56/18639 0.0178571428571429 0.212948999177406 0.992643573696964 0.999999999529632 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 4/1563 122/18639 0.0327868852459016 0.390988326358516 0.993253454710824 0.999999999529632 GO:0005126 cytokine receptor binding 13/1563 275/18639 0.0472727272727273 0.56373407782237 0.993465754422825 0.999999999529632 GO:0005085 guanyl-nucleotide exchange factor activity 10/1563 230/18639 0.0434782608695652 0.518484519736293 0.994432692840658 0.999999999529632 GO:0004497 monooxygenase activity 3/1563 106/18639 0.0283018867924528 0.337504074167964 0.994762306600792 0.999999999529632 GO:0015026 coreceptor activity 1/1563 61/18639 0.0163934426229508 0.195494163179258 0.995259064276389 0.999999999529632 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 12/1563 268/18639 0.0447761194029851 0.533961669579167 0.995748997796748 0.999999999529632 GO:0022824 transmitter-gated monoatomic ion channel activity 1/1563 63/18639 0.0158730158730159 0.189287999268805 0.996023253481228 0.999999999529632 GO:0022835 transmitter-gated channel activity 1/1563 63/18639 0.0158730158730159 0.189287999268805 0.996023253481228 0.999999999529632 GO:0120013 lipid transfer activity 1/1563 65/18639 0.0153846153846154 0.183463753137458 0.996664329372252 0.999999999529632 GO:0160215 deacylase activity 1/1563 65/18639 0.0153846153846154 0.183463753137458 0.996664329372252 0.999999999529632 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/1563 91/18639 0.021978021978022 0.262091075910654 0.996824423840541 0.999999999529632 GO:0019787 ubiquitin-like protein transferase activity 25/1563 479/18639 0.0521920668058455 0.622397909913087 0.997243053933049 0.999999999529632 GO:0001217 DNA-binding transcription repressor activity 12/1563 278/18639 0.0431654676258993 0.514754415277759 0.997416651281557 0.999999999529632 GO:0016755 aminoacyltransferase activity 26/1563 496/18639 0.0524193548387097 0.625108352423999 0.997456741246099 0.999999999529632 GO:0042562 hormone binding 2/1563 94/18639 0.0212765957446809 0.253726467104994 0.997489296196468 0.999999999529632 GO:0098960 postsynaptic neurotransmitter receptor activity 1/1563 69/18639 0.0144927536231884 0.172828173245431 0.997653244294723 0.999999999529632 GO:0140767 enzyme-substrate adaptor activity 4/1563 139/18639 0.0287769784172662 0.343169610185172 0.997838733562108 0.999999999529632 GO:0004896 cytokine receptor activity 2/1563 96/18639 0.0208333333333333 0.248440499040307 0.997854304209239 0.999999999529632 GO:0030527 structural constituent of chromatin 2/1563 98/18639 0.0204081632653061 0.243370284774178 0.998166924927076 0.999999999529632 GO:0015108 chloride transmembrane transporter activity 3/1563 121/18639 0.0247933884297521 0.295664726130613 0.998221357490502 0.999999999529632 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/1563 73/18639 0.0136986301369863 0.16335813635527 0.998349109697079 0.999999999529632 GO:0015081 sodium ion transmembrane transporter activity 5/1563 164/18639 0.0304878048780488 0.363571462010206 0.998479981190691 0.999999999529632 GO:0015085 calcium ion transmembrane transporter activity 4/1563 147/18639 0.0272108843537415 0.324493713032238 0.998752766263488 0.999999999529632 GO:0005543 phospholipid binding 24/1563 497/18639 0.0482897384305835 0.575862082282563 0.999306286458838 0.999999999529632 GO:0099094 ligand-gated monoatomic cation channel activity 3/1563 136/18639 0.0220588235294118 0.263054646042678 0.999411939001209 0.999999999529632 GO:0015103 inorganic anion transmembrane transporter activity 4/1563 165/18639 0.0242424242424242 0.289094398883266 0.999647864267393 0.999999999529632 GO:0004842 ubiquitin-protein transferase activity 20/1563 449/18639 0.044543429844098 0.531186813092862 0.999650294398202 0.999999999529632 GO:0008528 G protein-coupled peptide receptor activity 2/1563 122/18639 0.0163934426229508 0.195494163179258 0.999729757661659 0.999999999529632 GO:0030594 neurotransmitter receptor activity 1/1563 97/18639 0.0103092783505155 0.12293962839108 0.999800245202834 0.999999999529632 GO:0001653 peptide receptor activity 2/1563 128/18639 0.015625 0.18633037428023 0.999833560417821 0.999999999529632 GO:0140375 immune receptor activity 3/1563 156/18639 0.0192307692307692 0.229329691421822 0.99986996221458 0.999999999529632 GO:0001216 DNA-binding transcription activator activity 20/1563 491/18639 0.0407331975560081 0.48574924455946 0.999955706478901 0.999999999529632 GO:0045182 translation regulator activity 12/1563 356/18639 0.0337078651685393 0.401971144514654 0.999964285493159 0.999999999529632 GO:0003823 antigen binding 3/1563 174/18639 0.0172413793103448 0.205605930240254 0.999967432502786 0.999999999529632 GO:0005267 potassium channel activity 1/1563 124/18639 0.00806451612903226 0.0961705157575382 0.999981501393485 0.999999999529632 GO:0015276 ligand-gated monoatomic ion channel activity 3/1563 186/18639 0.0161290322580645 0.192341031515076 0.999987209772074 0.999999999529632 GO:0022834 ligand-gated channel activity 3/1563 188/18639 0.0159574468085106 0.190294850328746 0.999989063613111 0.999999999529632 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 18/1563 484/18639 0.0371900826446281 0.44349708919592 0.999989372016412 0.999999999529632 GO:0005262 calcium channel activity 1/1563 131/18639 0.00763358778625954 0.0910316332361431 0.999990023592556 0.999999999529632 GO:0061659 ubiquitin-like protein ligase activity 11/1563 372/18639 0.0295698924731183 0.352625224444307 0.999995666434641 0.999999999529632 GO:0061630 ubiquitin protein ligase activity 10/1563 353/18639 0.028328611898017 0.337822774899001 0.999995779170637 0.999999999529632 GO:0005244 voltage-gated monoatomic ion channel activity 2/1563 173/18639 0.0115606936416185 0.137862935883639 0.999995849448326 0.999999999529632 GO:0022832 voltage-gated channel activity 2/1563 175/18639 0.0114285714285714 0.13628735947354 0.999996484122093 0.999999999529632 GO:0015079 potassium ion transmembrane transporter activity 1/1563 160/18639 0.00625 0.0745321497120921 0.999999229318622 0.999999999529632 GO:0046873 metal ion transmembrane transporter activity 12/1563 450/18639 0.0266666666666667 0.318003838771593 0.999999896869568 0.999999999529632 GO:0030371 translation repressor activity 6/1563 329/18639 0.0182370820668693 0.217479828947138 0.999999939004865 0.999999999529632 GO:0022836 gated channel activity 5/1563 318/18639 0.0157232704402516 0.187502263426647 0.999999977348046 0.999999999529632 GO:0005216 monoatomic ion channel activity 10/1563 448/18639 0.0223214285714286 0.266186248971758 0.999999992761453 0.999999999529632 GO:0005261 monoatomic cation channel activity 4/1563 341/18639 0.0117302052785924 0.139884386556419 0.999999999529632 0.999999999529632