ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 93/1034 175/18639 0.531428571428571 9.57959104725062 8.33601132347287e-70 8.76948391229346e-67 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 29/1034 68/18639 0.426470588235294 7.68760666742519 4.43236702701817e-19 2.33142505621156e-16 GO:0009055 electron transfer activity 35/1034 116/18639 0.301724137931034 5.43891315947442 4.68880356169191e-17 1.6442071156333e-14 GO:0022853 active monoatomic ion transmembrane transporter activity 32/1034 118/18639 0.271186440677966 4.88843720289808 2.9897020398206e-14 7.86291636472817e-12 GO:0015399 primary active transmembrane transporter activity 36/1034 166/18639 0.216867469879518 3.90927734147421 1.20171450651025e-12 2.52840732169756e-10 GO:0008137 NADH dehydrogenase (ubiquinone) activity 17/1034 41/18639 0.414634146341463 7.47424163796764 1.67843005999363e-11 2.94284737185551e-09 GO:0019843 rRNA binding 21/1034 65/18639 0.323076923076923 5.82382085999107 2.03220271084255e-11 3.05411035972338e-09 GO:0031720 haptoglobin binding 9/1034 10/18639 0.9 16.223500967118 4.57617475176820e-11 6.01766979857519e-09 GO:0003954 NADH dehydrogenase activity 17/1034 44/18639 0.386363636363636 6.96463425356075 6.486778281484e-11 7.5823230579124e-09 GO:0015078 proton transmembrane transporter activity 35/1034 185/18639 0.189189189189189 3.41034554864342 1.42911694244867e-10 1.503431023456e-08 GO:0004601 peroxidase activity 18/1034 57/18639 0.315789473684211 5.69245647969052 8.46287714213697e-10 8.09358795775281e-08 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 18/1034 58/18639 0.310344827586207 5.59431067831655 1.1639757229671e-09 1.02041871713449e-07 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 18/1034 59/18639 0.305084745762712 5.49949185326034 1.58881438280676e-09 1.28571748516362e-07 GO:0005344 oxygen carrier activity 9/1034 14/18639 0.642857142857143 11.5882149765128 7.47916791614516e-09 5.62006046270336e-07 GO:1990948 ubiquitin ligase inhibitor activity 8/1034 11/18639 0.727272727272727 13.1098997714085 1.24102384676603e-08 8.70371391198577e-07 GO:0055105 ubiquitin-protein transferase inhibitor activity 9/1034 15/18639 0.6 10.815667311412 1.77743070783919e-08 1.15077791907686e-06 GO:0048027 mRNA 5'-UTR binding 11/1034 24/18639 0.458333333333333 8.26196808510638 1.85962211257667e-08 1.15077791907686e-06 GO:0022804 active transmembrane transporter activity 55/1034 457/18639 0.12035010940919 2.16944457376973 5.19061979467025e-08 3.03362890221839e-06 GO:0016860 intramolecular oxidoreductase activity 15/1034 53/18639 0.283018867924528 5.10172986387358 1.12055483707977e-07 6.2043352031996e-06 GO:0016209 antioxidant activity 19/1034 86/18639 0.22093023255814 3.98251315730287 1.8405445384804e-07 9.68126427240688e-06 GO:0016651 oxidoreductase activity, acting on NAD(P)H 18/1034 88/18639 0.204545454545455 3.68715931070863 1.28722535471958e-06 6.44838606269046e-05 GO:0016853 isomerase activity 27/1034 180/18639 0.15 2.703916827853 2.3068274044111e-06 0.000110308292247294 GO:0008135 translation factor activity, RNA binding 17/1034 83/18639 0.204819277108434 3.69209526694787 2.47575145451946e-06 0.000113238718702369 GO:0003697 single-stranded DNA binding 21/1034 121/18639 0.173553719008264 3.12849880908611 2.92012837848884e-06 0.000123943972356658 GO:0180051 translation factor activity 17/1034 84/18639 0.202380952380952 3.64814175186516 2.94543660543388e-06 0.000123943972356658 GO:0004129 cytochrome-c oxidase activity 7/1034 15/18639 0.466666666666667 8.41218568665377 6.88042523498562e-06 0.000278392590277111 GO:0015631 tubulin binding 43/1034 385/18639 0.111688311688312 2.01330603632344 1.01492412460281e-05 0.00038363821946658 GO:0019825 oxygen binding 10/1034 34/18639 0.294117647058824 5.30179770167255 1.02109031797189e-05 0.00038363821946658 GO:0051082 unfolded protein binding 20/1034 121/18639 0.165289256198347 2.97952267532011 1.06941425890604e-05 0.000387939241506606 GO:0016675 oxidoreductase activity, acting on a heme group of donors 7/1034 16/18639 0.4375 7.88642408123791 1.16456143650328e-05 0.000408372877067149 GO:0003743 translation initiation factor activity 12/1034 51/18639 0.235294117647059 4.24143816133804 1.6919936331975e-05 0.000574186226491537 GO:0055106 ubiquitin-protein transferase regulator activity 10/1034 36/18639 0.277777777777778 5.00725338491296 1.78845128293539e-05 0.000587953359265008 GO:0016835 carbon-oxygen lyase activity 15/1034 79/18639 0.189873417721519 3.42267952892785 2.49317348077984e-05 0.000794793485387998 GO:0008017 microtubule binding 33/1034 276/18639 0.119565217391304 2.15529602220167 2.74127405092431e-05 0.000848182441638933 GO:0000217 DNA secondary structure binding 10/1034 39/18639 0.256410256410256 4.62208004761196 3.84258500002225e-05 0.00115497126286383 GO:0016829 lyase activity 26/1034 200/18639 0.13 2.34339458413926 4.66574396202775e-05 0.00136343406890366 GO:0140662 ATP-dependent protein folding chaperone 10/1034 40/18639 0.25 4.50652804642166 4.87068482539828e-05 0.00138485417197811 GO:0044183 protein folding chaperone 14/1034 75/18639 0.186666666666667 3.36487427466151 5.61560693790675e-05 0.0015546364470205 GO:0140517 protein-RNA adaptor activity 7/1034 22/18639 0.318181818181818 5.73558114999121 0.000129411718223676 0.00349079814285404 GO:0005201 extracellular matrix structural constituent 21/1034 168/18639 0.125 2.25326402321083 0.000415026264992909 0.0107041828971323 GO:0008301 DNA binding, bending 6/1034 19/18639 0.315789473684211 5.69245647969052 0.000417178230781773 0.0107041828971323 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 5/1034 13/18639 0.384615384615385 6.93312007141794 0.000460483240321585 0.0115340087813883 GO:0019838 growth factor binding 18/1034 136/18639 0.132352941176471 2.38580896575265 0.000526848797996742 0.0128894171044784 GO:0019205 nucleobase-containing compound kinase activity 9/1034 44/18639 0.204545454545455 3.68715931070863 0.000586555810974787 0.0140240162078517 GO:0046625 sphingolipid binding 7/1034 28/18639 0.25 4.50652804642166 0.000670791755949859 0.0156816206057611 GO:0046906 tetrapyrrole binding 19/1034 152/18639 0.125 2.25326402321083 0.000765648149268724 0.017510040283276 GO:0020037 heme binding 18/1034 142/18639 0.126760563380282 2.2850001362138 0.000883537752491387 0.0197762067153391 GO:0045296 cadherin binding 33/1034 334/18639 0.0988023952095808 1.78102306026245 0.000970843914709765 0.0210176147640421 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 5/1034 15/18639 0.333333333333333 6.00870406189555 0.000978957341671162 0.0210176147640421 GO:0044389 ubiquitin-like protein ligase binding 32/1034 322/18639 0.0993788819875776 1.79141487559619 0.00104436966946665 0.0219735378455782 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 9/1034 48/18639 0.1875 3.37989603481625 0.0011373473906636 0.0234605775485904 GO:0003777 microtubule motor activity 11/1034 68/18639 0.161764705882353 2.9159887359199 0.00121312137357151 0.0245423785576389 GO:0004602 glutathione peroxidase activity 6/1034 23/18639 0.260869565217391 4.70246404844 0.00128261595012366 0.0254587165949074 GO:0017070 U6 snRNA binding 5/1034 16/18639 0.3125 5.63316005802708 0.00135932488101455 0.026481662496802 GO:0031625 ubiquitin protein ligase binding 30/1034 302/18639 0.0993377483443709 1.79067339592914 0.0014836943273747 0.0283790260436034 GO:0005540 hyaluronic acid binding 6/1034 24/18639 0.25 4.50652804642166 0.00163075113957369 0.0306348249791343 GO:0019842 vitamin binding 18/1034 150/18639 0.12 2.1631334622824 0.001665262192993 0.0307343127548884 GO:0004550 nucleoside diphosphate kinase activity 5/1034 17/18639 0.294117647058824 5.30179770167255 0.00183845903320683 0.0333458431540273 GO:0005518 collagen binding 11/1034 72/18639 0.152777777777778 2.75398936170213 0.00195508152731389 0.0348600977412578 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 4/1034 11/18639 0.363636363636364 6.55494988570424 0.00226904445454317 0.0385005607448292 GO:0048407 platelet-derived growth factor binding 4/1034 11/18639 0.363636363636364 6.55494988570424 0.00226904445454317 0.0385005607448292 GO:0070990 snRNP binding 4/1034 11/18639 0.363636363636364 6.55494988570424 0.00226904445454317 0.0385005607448292 GO:0003684 damaged DNA binding 11/1034 74/18639 0.148648648648649 2.67955721679126 0.00244512646205091 0.0408297307631358 GO:1901681 sulfur compound binding 27/1034 275/18639 0.0981818181818182 1.76983646914014 0.00293436237498382 0.0482335815387965 GO:0051087 protein-folding chaperone binding 16/1034 134/18639 0.119402985074627 2.15237160426109 0.00308903408973495 0.0494503410982088 GO:0005520 insulin-like growth factor binding 5/1034 19/18639 0.263157894736842 4.74371373307544 0.00314940385321292 0.0494503410982088 GO:0008574 plus-end-directed microtubule motor activity 5/1034 19/18639 0.263157894736842 4.74371373307544 0.00314940385321292 0.0494503410982088 GO:0004857 enzyme inhibitor activity 37/1034 416/18639 0.0889423076923077 1.6032840165154 0.00321315389335555 0.0497093808207359 GO:0043024 ribosomal small subunit binding 5/1034 20/18639 0.25 4.50652804642166 0.00400981525536447 0.0611351543281655 GO:0005539 glycosaminoglycan binding 24/1034 242/18639 0.0991735537190083 1.78771360519207 0.00428324517286871 0.0630803281483628 GO:0043021 ribonucleoprotein complex binding 19/1034 177/18639 0.107344632768362 1.93500639281382 0.00447919663119785 0.0630803281483628 GO:0005542 folic acid binding 4/1034 13/18639 0.307692307692308 5.54649605713436 0.004497171683581 0.0630803281483628 GO:0019104 DNA N-glycosylase activity 4/1034 13/18639 0.307692307692308 5.54649605713436 0.004497171683581 0.0630803281483628 GO:0031994 insulin-like growth factor I binding 4/1034 13/18639 0.307692307692308 5.54649605713436 0.004497171683581 0.0630803281483628 GO:0070700 BMP receptor binding 4/1034 13/18639 0.307692307692308 5.54649605713436 0.004497171683581 0.0630803281483628 GO:0003774 cytoskeletal motor activity 17/1034 153/18639 0.111111111111111 2.00290135396518 0.00492413208301926 0.0681603546228456 GO:0016776 phosphotransferase activity, phosphate group as acceptor 7/1034 39/18639 0.179487179487179 3.23545603332837 0.00512189762954761 0.0699770948868064 GO:0033218 amide binding 24/1034 247/18639 0.097165991902834 1.75152507067401 0.00552261234298197 0.0744844639079107 GO:0016887 ATP hydrolysis activity 36/1034 417/18639 0.0863309352517986 1.55621112394417 0.00581181096912826 0.0773927232851003 GO:0140104 molecular carrier activity 24/1034 249/18639 0.0963855421686747 1.73745659621076 0.00609532533377088 0.080153528139087 GO:0030021 extracellular matrix structural constituent conferring compression resistance 5/1034 22/18639 0.227272727272727 4.09684367856515 0.00621167009143555 0.0806750239035827 GO:0008171 O-methyltransferase activity 5/1034 23/18639 0.217391304347826 3.91872004036666 0.00758085179735553 0.0972567815953416 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 14/1034 122/18639 0.114754098360656 2.0685702508165 0.00770388534153377 0.0976444262565485 GO:0005041 low-density lipoprotein particle receptor activity 4/1034 15/18639 0.266666666666667 4.80696324951644 0.00785659331519665 0.098394478185558 GO:0043022 ribosome binding 13/1034 112/18639 0.116071428571429 2.09231659298149 0.00913229041802954 0.113025523761966 GO:0051287 NAD binding 8/1034 54/18639 0.148148148148148 2.67053513862024 0.0093756692523859 0.11468841922686 GO:0003688 DNA replication origin binding 4/1034 16/18639 0.25 4.50652804642166 0.010022349459924 0.118708214302491 GO:0005521 lamin binding 4/1034 16/18639 0.25 4.50652804642166 0.010022349459924 0.118708214302491 GO:0030020 extracellular matrix structural constituent conferring tensile strength 7/1034 44/18639 0.159090909090909 2.8677905749956 0.0100428052023971 0.118708214302491 GO:0015035 protein-disulfide reductase activity 6/1034 34/18639 0.176470588235294 3.18107862100353 0.0101622078089772 0.118784917944933 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 14/1034 132/18639 0.106060606060606 1.9118603833304 0.0148672551463906 0.165626254474143 GO:0019887 protein kinase regulator activity 23/1034 255/18639 0.0901960784313725 1.62588462851291 0.0151067285121305 0.165626254474143 GO:0003680 minor groove of adenine-thymine-rich DNA binding 3/1034 10/18639 0.3 5.407833655706 0.015226277801681 0.165626254474143 GO:0005345 purine nucleobase transmembrane transporter activity 3/1034 10/18639 0.3 5.407833655706 0.015226277801681 0.165626254474143 GO:0047429 nucleoside triphosphate diphosphatase activity 3/1034 10/18639 0.3 5.407833655706 0.015226277801681 0.165626254474143 GO:0000400 four-way junction DNA binding 4/1034 18/18639 0.222222222222222 4.00580270793037 0.0154290617285798 0.165626254474143 GO:0003746 translation elongation factor activity 4/1034 18/18639 0.222222222222222 4.00580270793037 0.0154290617285798 0.165626254474143 GO:0030228 lipoprotein particle receptor activity 4/1034 18/18639 0.222222222222222 4.00580270793037 0.0154290617285798 0.165626254474143 GO:0042162 telomeric DNA binding 6/1034 38/18639 0.157894736842105 2.84622823984526 0.017299998507423 0.182826168354083 GO:0019207 kinase regulator activity 25/1034 287/18639 0.0871080139372822 1.57021883150581 0.0173789133416428 0.182826168354083 GO:0003756 protein disulfide isomerase activity 4/1034 19/18639 0.210526315789474 3.79497098646035 0.018703637162011 0.187790540367059 GO:0005346 purine ribonucleotide transmembrane transporter activity 4/1034 19/18639 0.210526315789474 3.79497098646035 0.018703637162011 0.187790540367059 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 4/1034 19/18639 0.210526315789474 3.79497098646035 0.018703637162011 0.187790540367059 GO:0050145 nucleoside monophosphate kinase activity 4/1034 19/18639 0.210526315789474 3.79497098646035 0.018703637162011 0.187790540367059 GO:0002020 protease binding 14/1034 136/18639 0.102941176470588 1.85562919558539 0.0188592620667381 0.187790540367059 GO:0016836 hydro-lyase activity 8/1034 61/18639 0.131147540983607 2.36408028664743 0.0189218605312816 0.187790540367059 GO:0043539 protein serine/threonine kinase activator activity 9/1034 73/18639 0.123287671232877 2.22239739275589 0.0192502831397949 0.189264466009946 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 6/1034 39/18639 0.153846153846154 2.77324802856718 0.0195141986670366 0.189393079850342 GO:0000099 sulfur amino acid transmembrane transporter activity 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.189393079850342 GO:0004523 RNA-DNA hybrid ribonuclease activity 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.189393079850342 GO:0015205 nucleobase transmembrane transporter activity 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.189393079850342 GO:0043236 laminin binding 5/1034 29/18639 0.172413793103448 3.10795037684253 0.0203435532538866 0.189393079850342 GO:0051861 glycolipid binding 5/1034 29/18639 0.172413793103448 3.10795037684253 0.0203435532538866 0.189393079850342 GO:0048029 monosaccharide binding 9/1034 74/18639 0.121621621621622 2.19236499555648 0.0208747195370045 0.192633376780077 GO:0015036 disulfide oxidoreductase activity 6/1034 40/18639 0.15 2.703916827853 0.0219136437697953 0.200462202137605 GO:0016408 C-acyltransferase activity 4/1034 20/18639 0.2 3.60522243713733 0.0223770926386726 0.202937081516238 GO:1901682 sulfur compound transmembrane transporter activity 8/1034 63/18639 0.126984126984127 2.28903011881735 0.0226029036267753 0.203232945430492 GO:0001968 fibronectin binding 5/1034 30/18639 0.166666666666667 3.00435203094778 0.0233291953054671 0.20623792824665 GO:0015215 nucleotide transmembrane transporter activity 5/1034 30/18639 0.166666666666667 3.00435203094778 0.0233291953054671 0.20623792824665 GO:0005506 iron ion binding 15/1034 154/18639 0.0974025974025974 1.75579014795649 0.0242406417460037 0.212509625973299 GO:0016877 ligase activity, forming carbon-sulfur bonds 6/1034 41/18639 0.146341463414634 2.63796763692975 0.0245042991752669 0.21304564241637 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 3/1034 12/18639 0.25 4.50652804642166 0.025695282508797 0.21799546128431 GO:0097371 MDM2/MDM4 family protein binding 3/1034 12/18639 0.25 4.50652804642166 0.025695282508797 0.21799546128431 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/1034 12/18639 0.25 4.50652804642166 0.025695282508797 0.21799546128431 GO:0051540 metal cluster binding 9/1034 77/18639 0.116883116883117 2.10694817754779 0.0263370691471818 0.220204924604994 GO:0070182 DNA polymerase binding 4/1034 21/18639 0.19047619047619 3.43354517822603 0.0264597285532192 0.220204924604994 GO:0072349 modified amino acid transmembrane transporter activity 5/1034 31/18639 0.161290322580645 2.9074374493043 0.0265836743582075 0.220204924604994 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 7/1034 54/18639 0.12962962962963 2.33671824629271 0.0288643120979032 0.235389583930187 GO:0017069 snRNA binding 7/1034 54/18639 0.12962962962963 2.33671824629271 0.0288643120979032 0.235389583930187 GO:0140142 nucleocytoplasmic carrier activity 5/1034 32/18639 0.15625 2.81658002901354 0.0301136676412872 0.243689064297185 GO:0000287 magnesium ion binding 20/1034 230/18639 0.0869565217391304 1.56748801614667 0.0314090136142058 0.252231162764462 GO:0001223 transcription coactivator binding 6/1034 44/18639 0.136363636363636 2.45810620713909 0.0334763134436688 0.266796073808633 GO:0042393 histone binding 21/1034 247/18639 0.0850202429149798 1.53258443683976 0.034547724690747 0.273264709583953 GO:0000295 adenine nucleotide transmembrane transporter activity 4/1034 23/18639 0.173913043478261 3.13497603229333 0.0358810750587931 0.27960659971741 GO:0017134 fibroblast growth factor binding 4/1034 23/18639 0.173913043478261 3.13497603229333 0.0358810750587931 0.27960659971741 GO:0015932 nucleobase-containing compound transmembrane transporter activity 7/1034 57/18639 0.12280701754386 2.2137330754352 0.0374093258272677 0.289372138016806 GO:0030332 cyclin binding 5/1034 34/18639 0.147058823529412 2.65089885083627 0.0380218490326981 0.291963395491959 GO:0005347 ATP transmembrane transporter activity 3/1034 14/18639 0.214285714285714 3.86273832550428 0.0391543954020269 0.296333985344837 GO:1990825 sequence-specific mRNA binding 3/1034 14/18639 0.214285714285714 3.86273832550428 0.0391543954020269 0.296333985344837 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 6/1034 46/18639 0.130434782608696 2.35123202422 0.0405019070817454 0.304342901785687 GO:0050699 WW domain binding 4/1034 24/18639 0.166666666666667 3.00435203094778 0.0412279565185658 0.305435283503741 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 4/1034 24/18639 0.166666666666667 3.00435203094778 0.0412279565185658 0.305435283503741 GO:0016846 carbon-sulfur lyase activity 3/1034 15/18639 0.2 3.60522243713733 0.0469788459237345 0.32589056644551 GO:0031386 protein tag activity 3/1034 15/18639 0.2 3.60522243713733 0.0469788459237345 0.32589056644551 GO:0141047 molecular tag activity 3/1034 15/18639 0.2 3.60522243713733 0.0469788459237345 0.32589056644551 GO:0061134 peptidase regulator activity 19/1034 226/18639 0.084070796460177 1.51546960853118 0.0469876952217244 0.32589056644551 GO:0015645 fatty acid ligase activity 4/1034 25/18639 0.16 2.88417794970986 0.0470005614359583 0.32589056644551 GO:0120515 fatty acid-CoA ligase activity 4/1034 25/18639 0.16 2.88417794970986 0.0470005614359583 0.32589056644551 GO:0004869 cysteine-type endopeptidase inhibitor activity 5/1034 36/18639 0.138888888888889 2.50362669245648 0.0470868499046744 0.32589056644551 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 5/1034 36/18639 0.138888888888889 2.50362669245648 0.0470868499046744 0.32589056644551 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 5/1034 36/18639 0.138888888888889 2.50362669245648 0.0470868499046744 0.32589056644551 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 5/1034 36/18639 0.138888888888889 2.50362669245648 0.0470868499046744 0.32589056644551 GO:0003713 transcription coactivator activity 21/1034 256/18639 0.08203125 1.47870451523211 0.0476717121452365 0.327781968475744 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 7/1034 61/18639 0.114754098360656 2.0685702508165 0.0511679038339898 0.349536589826995 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 12/1034 128/18639 0.09375 1.68994801740812 0.0521558602021628 0.353986870533389 GO:0015216 purine nucleotide transmembrane transporter activity 4/1034 26/18639 0.153846153846154 2.77324802856718 0.0531973564233229 0.358741147162408 GO:0017124 SH3 domain binding 11/1034 115/18639 0.0956521739130435 1.72423681776133 0.0544342093246542 0.362849945636118 GO:0005159 insulin-like growth factor receptor binding 3/1034 16/18639 0.1875 3.37989603481625 0.0555072681846138 0.362849945636118 GO:0008142 oxysterol binding 3/1034 16/18639 0.1875 3.37989603481625 0.0555072681846138 0.362849945636118 GO:0140328 floppase activity 3/1034 16/18639 0.1875 3.37989603481625 0.0555072681846138 0.362849945636118 GO:0008201 heparin binding 15/1034 172/18639 0.0872093023255814 1.57204466735639 0.0555312179157937 0.362849945636118 GO:0031406 carboxylic acid binding 16/1034 187/18639 0.0855614973262032 1.54234114957747 0.0566183447144696 0.367669744689025 GO:0051536 iron-sulfur cluster binding 8/1034 76/18639 0.105263157894737 1.89748549323017 0.0591835905301224 0.379067189415699 GO:0004364 glutathione transferase activity 4/1034 27/18639 0.148148148148148 2.67053513862024 0.0598147846416407 0.379067189415699 GO:0016405 CoA-ligase activity 4/1034 27/18639 0.148148148148148 2.67053513862024 0.0598147846416407 0.379067189415699 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 4/1034 27/18639 0.148148148148148 2.67053513862024 0.0598147846416407 0.379067189415699 GO:0043177 organic acid binding 16/1034 189/18639 0.0846560846560847 1.52602007921157 0.0611485711192772 0.385199382140596 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 5/1034 39/18639 0.128205128205128 2.31104002380598 0.0628860926527608 0.393523642520123 GO:0005178 integrin binding 14/1034 161/18639 0.0869565217391304 1.56748801614667 0.0639833957851494 0.393523642520123 GO:0004029 aldehyde dehydrogenase (NAD+) activity 3/1034 17/18639 0.176470588235294 3.18107862100353 0.0647144393117693 0.393523642520123 GO:0016018 cyclosporin A binding 3/1034 17/18639 0.176470588235294 3.18107862100353 0.0647144393117693 0.393523642520123 GO:0048038 quinone binding 3/1034 17/18639 0.176470588235294 3.18107862100353 0.0647144393117693 0.393523642520123 GO:0070402 NADPH binding 3/1034 17/18639 0.176470588235294 3.18107862100353 0.0647144393117693 0.393523642520123 GO:0038024 cargo receptor activity 7/1034 65/18639 0.107692307692308 1.94127361999702 0.0677487267085072 0.409607244237642 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 5/1034 40/18639 0.125 2.25326402321083 0.0687392996360416 0.41322138981209 GO:1901505 carbohydrate derivative transmembrane transporter activity 6/1034 53/18639 0.113207547169811 2.04069194554943 0.0720130211620902 0.430441467400676 GO:0008514 organic anion transmembrane transporter activity 21/1034 269/18639 0.0780669144981413 1.4072429587339 0.0724546949162509 0.430634683909017 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 3/1034 18/18639 0.166666666666667 3.00435203094778 0.0745715148284071 0.43284048507934 GO:0008525 phosphatidylcholine transporter activity 3/1034 18/18639 0.166666666666667 3.00435203094778 0.0745715148284071 0.43284048507934 GO:0015172 acidic amino acid transmembrane transporter activity 3/1034 18/18639 0.166666666666667 3.00435203094778 0.0745715148284071 0.43284048507934 GO:0031690 adrenergic receptor binding 3/1034 18/18639 0.166666666666667 3.00435203094778 0.0745715148284071 0.43284048507934 GO:0140318 protein transporter activity 5/1034 41/18639 0.121951219512195 2.19830636410813 0.0748830497000379 0.43284048507934 GO:0050840 extracellular matrix binding 7/1034 67/18639 0.104477611940299 1.88332515372846 0.0771167907624565 0.442563877741628 GO:0050661 NADP binding 6/1034 54/18639 0.111111111111111 2.00290135396518 0.0774066097951137 0.442563877741628 GO:0001618 virus receptor activity 8/1034 81/18639 0.0987654320987654 1.78035675908016 0.079722438970429 0.453340571875088 GO:0016874 ligase activity 14/1034 167/18639 0.0838323353293413 1.51117108143481 0.0810270730275085 0.457134837384519 GO:0016859 cis-trans isomerase activity 5/1034 42/18639 0.119047619047619 2.14596573639127 0.0813143156888954 0.457134837384519 GO:0005548 phospholipid transporter activity 7/1034 68/18639 0.102941176470588 1.85562919558539 0.0820704227478613 0.457134837384519 GO:0033612 receptor serine/threonine kinase binding 4/1034 30/18639 0.133333333333333 2.40348162475822 0.082127836754443 0.457134837384519 GO:0140272 exogenous protein binding 8/1034 82/18639 0.0975609756097561 1.7586450912865 0.0842805971211815 0.466648358797278 GO:0097001 ceramide binding 3/1034 19/18639 0.157894736842105 2.84622823984526 0.0850467418908564 0.468424986749638 GO:0016878 acid-thiol ligase activity 4/1034 31/18639 0.129032258064516 2.32594995944344 0.0903566015538853 0.49507887934733 GO:0097110 scaffold protein binding 7/1034 70/18639 0.1 1.80261121856867 0.0925134781712948 0.504270357700529 GO:0016504 peptidase activator activity 6/1034 57/18639 0.105263157894737 1.89748549323017 0.0949094479458169 0.508403164568026 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 3/1034 20/18639 0.15 2.703916827853 0.0961060917588888 0.508403164568026 GO:0061608 nuclear import signal receptor activity 3/1034 20/18639 0.15 2.703916827853 0.0961060917588888 0.508403164568026 GO:0042910 xenobiotic transmembrane transporter activity 4/1034 32/18639 0.125 2.25326402321083 0.0989627349699707 0.508403164568026 GO:0071813 lipoprotein particle binding 4/1034 32/18639 0.125 2.25326402321083 0.0989627349699707 0.508403164568026 GO:0071814 protein-lipid complex binding 4/1034 32/18639 0.125 2.25326402321083 0.0989627349699707 0.508403164568026 GO:0140297 DNA-binding transcription factor binding 34/1034 488/18639 0.069672131147541 1.25591765228145 0.101558352057887 0.508403164568026 GO:0140303 intramembrane lipid transporter activity 5/1034 45/18639 0.111111111111111 2.00290135396518 0.102290844602534 0.508403164568026 GO:0001094 TFIID-class transcription factor complex binding 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.508403164568026 GO:0005337 nucleoside transmembrane transporter activity 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.508403164568026 GO:0005522 profilin binding 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.508403164568026 GO:0008641 ubiquitin-like modifier activating enzyme activity 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.508403164568026 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.508403164568026 GO:0030957 Tat protein binding 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.508403164568026 GO:0031956 medium-chain fatty acid-CoA ligase activity 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.508403164568026 GO:0043208 glycosphingolipid binding 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.508403164568026 GO:0097177 mitochondrial ribosome binding 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.508403164568026 GO:0098505 G-rich strand telomeric DNA binding 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.508403164568026 GO:0140940 histone H2A methyltransferase activity 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.508403164568026 GO:1990259 histone H2AQ104 methyltransferase activity 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.508403164568026 GO:0001221 transcription coregulator binding 10/1034 115/18639 0.0869565217391304 1.56748801614667 0.105709678702432 0.519656925210086 GO:0070888 E-box binding 6/1034 59/18639 0.101694915254237 1.83316395108678 0.107656432810773 0.523253546479917 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 4/1034 33/18639 0.121212121212121 2.18498329523475 0.107933478694051 0.523253546479917 GO:0140416 transcription regulator inhibitor activity 4/1034 33/18639 0.121212121212121 2.18498329523475 0.107933478694051 0.523253546479917 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 4/1034 34/18639 0.117647058823529 2.12071908066902 0.117255029315565 0.552635531013592 GO:0001784 phosphotyrosine residue binding 5/1034 47/18639 0.106382978723404 1.9176715091156 0.117622216327532 0.552635531013592 GO:0005504 fatty acid binding 5/1034 47/18639 0.106382978723404 1.9176715091156 0.117622216327532 0.552635531013592 GO:0034062 5'-3' RNA polymerase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.552635531013592 GO:0070034 telomerase RNA binding 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.552635531013592 GO:0097747 RNA polymerase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.552635531013592 GO:0003727 single-stranded RNA binding 8/1034 89/18639 0.0898876404494382 1.62032469084824 0.120338760236836 0.552635531013592 GO:0008046 axon guidance receptor activity 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.552635531013592 GO:0010854 adenylate cyclase regulator activity 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.552635531013592 GO:0015217 ADP transmembrane transporter activity 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.552635531013592 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.552635531013592 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.552635531013592 GO:0048185 activin binding 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.552635531013592 GO:0050786 RAGE receptor binding 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.552635531013592 GO:0019210 kinase inhibitor activity 8/1034 90/18639 0.0888888888888889 1.60232108317215 0.1260686571688 0.571656152334388 GO:0044325 transmembrane transporter binding 11/1034 136/18639 0.0808823529411765 1.45799436795995 0.134661880626195 0.608001280767198 GO:0005049 nuclear export signal receptor activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.61067885023602 GO:0008179 adenylate cyclase binding 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.61067885023602 GO:0010853 cyclase activator activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.61067885023602 GO:0015132 prostaglandin transmembrane transporter activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.61067885023602 GO:0016208 AMP binding 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.61067885023602 GO:0016801 hydrolase activity, acting on ether bonds 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.61067885023602 GO:0016803 ether hydrolase activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.61067885023602 GO:0036009 protein-glutamine N-methyltransferase activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.61067885023602 GO:0043047 single-stranded telomeric DNA binding 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.61067885023602 GO:0015605 organophosphate ester transmembrane transporter activity 5/1034 50/18639 0.1 1.80261121856867 0.142500279316421 0.61691478946862 GO:0061135 endopeptidase regulator activity 14/1034 184/18639 0.0760869565217391 1.37155201412833 0.14381127519782 0.620038776672568 GO:0001091 RNA polymerase II general transcription initiation factor binding 3/1034 24/18639 0.125 2.25326402321083 0.145453990017363 0.624553260688025 GO:0030414 peptidase inhibitor activity 13/1034 169/18639 0.0769230769230769 1.38662401428359 0.146045724457466 0.624553260688025 GO:0033293 monocarboxylic acid binding 7/1034 79/18639 0.0886075949367089 1.59725044683299 0.148000837506613 0.630351745169865 GO:0030295 protein kinase activator activity 11/1034 139/18639 0.079136690647482 1.42652686361549 0.149638628862346 0.634757409528983 GO:0016830 carbon-carbon lyase activity 5/1034 51/18639 0.0980392156862745 1.76726590055752 0.151261713996885 0.639065554717764 GO:0000049 tRNA binding 7/1034 80/18639 0.0875 1.57728481624758 0.154970760500995 0.645681832424637 GO:0003712 transcription coregulator activity 33/1034 495/18639 0.0666666666666667 1.20174081237911 0.157690167852618 0.645681832424637 GO:0008139 nuclear localization sequence binding 3/1034 25/18639 0.12 2.1631334622824 0.158879457551191 0.645681832424637 GO:0008035 high-density lipoprotein particle binding 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.645681832424637 GO:0008253 5'-nucleotidase activity 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.645681832424637 GO:0030955 potassium ion binding 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.645681832424637 GO:0035673 oligopeptide transmembrane transporter activity 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.645681832424637 GO:0039706 co-receptor binding 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.645681832424637 GO:0043560 insulin receptor substrate binding 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.645681832424637 GO:0071714 icosanoid transmembrane transporter activity 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.645681832424637 GO:0140333 glycerophospholipid flippase activity 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.645681832424637 GO:0140666 annealing activity 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.645681832424637 GO:0046943 carboxylic acid transmembrane transporter activity 14/1034 188/18639 0.074468085106383 1.34237005638092 0.161632784844369 0.648998815481969 GO:0005342 organic acid transmembrane transporter activity 14/1034 189/18639 0.0740740740740741 1.33526756931012 0.16625990984372 0.665039639374881 GO:0030507 spectrin binding 3/1034 26/18639 0.115384615384615 2.07993602142538 0.172664079437435 0.682866960782638 GO:0050750 low-density lipoprotein particle receptor binding 3/1034 26/18639 0.115384615384615 2.07993602142538 0.172664079437435 0.682866960782638 GO:0120014 phospholipid transfer activity 3/1034 26/18639 0.115384615384615 2.07993602142538 0.172664079437435 0.682866960782638 GO:0140463 chromatin-protein adaptor activity 5/1034 54/18639 0.0925925925925926 1.66908446163765 0.178823533775589 0.687482055481208 GO:0050997 quaternary ammonium group binding 4/1034 40/18639 0.1 1.80261121856867 0.179678724335333 0.687482055481208 GO:0071949 FAD binding 4/1034 40/18639 0.1 1.80261121856867 0.179678724335333 0.687482055481208 GO:0005313 L-glutamate transmembrane transporter activity 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.687482055481208 GO:0008392 arachidonate epoxygenase activity 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.687482055481208 GO:0008559 ABC-type xenobiotic transporter activity 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.687482055481208 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.687482055481208 GO:0019992 diacylglycerol binding 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.687482055481208 GO:0044548 S100 protein binding 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.687482055481208 GO:0098847 sequence-specific single stranded DNA binding 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.687482055481208 GO:0004866 endopeptidase inhibitor activity 12/1034 161/18639 0.0745341614906832 1.34356115669714 0.183789107397773 0.694884506387549 GO:0004860 protein kinase inhibitor activity 7/1034 84/18639 0.0833333333333333 1.50217601547389 0.184289712245367 0.694884506387549 GO:0051117 ATPase binding 7/1034 84/18639 0.0833333333333333 1.50217601547389 0.184289712245367 0.694884506387549 GO:0008266 poly(U) RNA binding 3/1034 27/18639 0.111111111111111 2.00290135396518 0.18677024128691 0.699225244960245 GO:0008320 protein transmembrane transporter activity 3/1034 27/18639 0.111111111111111 2.00290135396518 0.18677024128691 0.699225244960245 GO:0005319 lipid transporter activity 13/1034 178/18639 0.0730337078651685 1.31651381131419 0.190049546449274 0.707343966505474 GO:0017080 sodium channel regulator activity 4/1034 41/18639 0.0975609756097561 1.7586450912865 0.191007986458068 0.707343966505474 GO:0031072 heat shock protein binding 10/1034 131/18639 0.0763358778625954 1.37603909814402 0.191444585149672 0.707343966505474 GO:0008028 monocarboxylic acid transmembrane transporter activity 6/1034 70/18639 0.0857142857142857 1.54509533020171 0.191628355944924 0.707343966505474 GO:0019212 phosphatase inhibitor activity 5/1034 56/18639 0.0892857142857143 1.60947430229345 0.198163209254089 0.710291774845999 GO:0030170 pyridoxal phosphate binding 5/1034 56/18639 0.0892857142857143 1.60947430229345 0.198163209254089 0.710291774845999 GO:0019209 kinase activator activity 11/1034 148/18639 0.0743243243243243 1.33977860839563 0.199336324575687 0.710291774845999 GO:0140299 molecular sensor activity 6/1034 71/18639 0.0845070422535211 1.52333342414253 0.200270919378739 0.710291774845999 GO:0004467 long-chain fatty acid-CoA ligase activity 2/1034 15/18639 0.133333333333333 2.40348162475822 0.200887117422394 0.710291774845999 GO:0008252 nucleotidase activity 2/1034 15/18639 0.133333333333333 2.40348162475822 0.200887117422394 0.710291774845999 GO:0034483 heparan sulfate sulfotransferase activity 2/1034 15/18639 0.133333333333333 2.40348162475822 0.200887117422394 0.710291774845999 GO:0050780 dopamine receptor binding 2/1034 15/18639 0.133333333333333 2.40348162475822 0.200887117422394 0.710291774845999 GO:0016866 intramolecular transferase activity 3/1034 28/18639 0.107142857142857 1.93136916275214 0.20116098199149 0.710291774845999 GO:0051537 2 iron, 2 sulfur cluster binding 3/1034 28/18639 0.107142857142857 1.93136916275214 0.20116098199149 0.710291774845999 GO:0004520 DNA endonuclease activity 4/1034 42/18639 0.0952380952380952 1.71677258911301 0.202554688644296 0.710291774845999 GO:0019894 kinesin binding 4/1034 42/18639 0.0952380952380952 1.71677258911301 0.202554688644296 0.710291774845999 GO:0035198 miRNA binding 4/1034 42/18639 0.0952380952380952 1.71677258911301 0.202554688644296 0.710291774845999 GO:0042056 chemoattractant activity 4/1034 42/18639 0.0952380952380952 1.71677258911301 0.202554688644296 0.710291774845999 GO:0048487 beta-tubulin binding 4/1034 42/18639 0.0952380952380952 1.71677258911301 0.202554688644296 0.710291774845999 GO:0070279 vitamin B6 binding 5/1034 57/18639 0.087719298245614 1.58123791102515 0.20809145553373 0.727283093759084 GO:0030246 carbohydrate binding 19/1034 280/18639 0.0678571428571429 1.22320046974302 0.213043312206354 0.737083698067069 GO:0004712 protein serine/threonine/tyrosine kinase activity 4/1034 43/18639 0.0930232558139535 1.67684764518015 0.214300887751169 0.737083698067069 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 4/1034 43/18639 0.0930232558139535 1.67684764518015 0.214300887751169 0.737083698067069 GO:0003785 actin monomer binding 3/1034 29/18639 0.103448275862069 1.86477022610552 0.215800170156518 0.737083698067069 GO:0004629 phospholipase C activity 3/1034 29/18639 0.103448275862069 1.86477022610552 0.215800170156518 0.737083698067069 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 3/1034 29/18639 0.103448275862069 1.86477022610552 0.215800170156518 0.737083698067069 GO:0097472 cyclin-dependent protein kinase activity 3/1034 29/18639 0.103448275862069 1.86477022610552 0.215800170156518 0.737083698067069 GO:0015297 antiporter activity 10/1034 135/18639 0.0740740740740741 1.33526756931012 0.216675910570671 0.737679799094971 GO:0000062 fatty-acyl-CoA binding 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.737916968398127 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.737916968398127 GO:0008391 arachidonate monooxygenase activity 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.737916968398127 GO:0015562 efflux transmembrane transporter activity 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.737916968398127 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.737916968398127 GO:0019841 retinol binding 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.737916968398127 GO:0140327 flippase activity 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.737916968398127 GO:0140789 histone phosphatase activity 10/1034 136/18639 0.0735294117647059 1.32544942541814 0.223184960566265 0.738160953879838 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 7/1034 89/18639 0.0786516853932584 1.41778410449221 0.223833977459761 0.738160953879838 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 7/1034 89/18639 0.0786516853932584 1.41778410449221 0.223833977459761 0.738160953879838 GO:0030547 signaling receptor inhibitor activity 4/1034 44/18639 0.0909090909090909 1.63873747142606 0.226228655202486 0.743726703978172 GO:0031491 nucleosome binding 6/1034 74/18639 0.0810810810810811 1.46157666370432 0.227009944559684 0.74397028559747 GO:0045309 protein phosphorylated amino acid binding 5/1034 59/18639 0.0847457627118644 1.52763662590565 0.22841117438288 0.746237749847173 GO:0001965 G-protein alpha-subunit binding 3/1034 30/18639 0.1 1.80261121856867 0.230652651645638 0.746604890865264 GO:0008187 poly-pyrimidine tract binding 3/1034 30/18639 0.1 1.80261121856867 0.230652651645638 0.746604890865264 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/1034 30/18639 0.1 1.80261121856867 0.230652651645638 0.746604890865264 GO:0140793 histone H2AXY142 phosphatase activity 7/1034 90/18639 0.0777777777777778 1.40203094777563 0.232079245436107 0.748918301223264 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 5/1034 60/18639 0.0833333333333333 1.50217601547389 0.238780909529822 0.757256335098471 GO:0140097 catalytic activity, acting on DNA 22/1034 336/18639 0.0654761904761905 1.1802811550152 0.240020177619975 0.757256335098471 GO:0005092 GDP-dissociation inhibitor activity 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.757256335098471 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.757256335098471 GO:0030169 low-density lipoprotein particle binding 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.757256335098471 GO:0038191 neuropilin binding 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.757256335098471 GO:0045125 bioactive lipid receptor activity 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.757256335098471 GO:0046965 nuclear retinoid X receptor binding 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.757256335098471 GO:0051787 misfolded protein binding 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.757256335098471 GO:0070492 oligosaccharide binding 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.757256335098471 GO:1901567 fatty acid derivative binding 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.757256335098471 GO:0015291 secondary active transmembrane transporter activity 19/1034 287/18639 0.0662020905923345 1.19336631194441 0.24481214922936 0.760176348840701 GO:0017147 Wnt-protein binding 3/1034 31/18639 0.0967741935483871 1.74446246958258 0.245684371298325 0.760176348840701 GO:0070325 lipoprotein particle receptor binding 3/1034 31/18639 0.0967741935483871 1.74446246958258 0.245684371298325 0.760176348840701 GO:0043178 alcohol binding 7/1034 92/18639 0.0760869565217391 1.37155201412833 0.248863813505047 0.76775581175164 GO:0030291 protein serine/threonine kinase inhibitor activity 4/1034 46/18639 0.0869565217391304 1.56748801614667 0.250557679208506 0.77072128224371 GO:0015179 L-amino acid transmembrane transporter activity 5/1034 62/18639 0.0806451612903226 1.45371872465215 0.259885466870637 0.797083122880205 GO:0022884 macromolecule transmembrane transporter activity 3/1034 32/18639 0.09375 1.68994801740812 0.260862471608155 0.797753837592382 GO:0000900 mRNA regulatory element binding translation repressor activity 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.799102748830756 GO:0034185 apolipoprotein binding 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.799102748830756 GO:1901611 phosphatidylglycerol binding 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.799102748830756 GO:0005507 copper ion binding 5/1034 63/18639 0.0793650793650794 1.43064382426085 0.270598434904097 0.818015958388247 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4/1034 48/18639 0.0833333333333333 1.50217601547389 0.27540120709125 0.819614702385274 GO:0019955 cytokine binding 10/1034 144/18639 0.0694444444444444 1.25181334622824 0.277752382115382 0.819614702385274 GO:0004536 DNA nuclease activity 5/1034 64/18639 0.078125 1.40829001450677 0.281404038229727 0.819614702385274 GO:0005200 structural constituent of cytoskeleton 8/1034 112/18639 0.0714285714285714 1.28757944183476 0.282213026918511 0.819614702385274 GO:0016407 acetyltransferase activity 7/1034 96/18639 0.0729166666666667 1.31440401353965 0.283454818608982 0.819614702385274 GO:0048306 calcium-dependent protein binding 6/1034 80/18639 0.075 1.3519584139265 0.283477112312441 0.819614702385274 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.819614702385274 GO:0015245 fatty acid transmembrane transporter activity 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.819614702385274 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.819614702385274 GO:0016918 retinal binding 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.819614702385274 GO:0031420 alkali metal ion binding 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.819614702385274 GO:0046624 sphingolipid transporter activity 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.819614702385274 GO:0120227 acyl-CoA binding 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.819614702385274 GO:0008083 growth factor activity 11/1034 162/18639 0.0679012345679012 1.22399527186761 0.288396376695571 0.819614702385274 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 15/1034 229/18639 0.0655021834061135 1.18074970648603 0.290400701091007 0.819614702385274 GO:0008376 acetylgalactosaminyltransferase activity 3/1034 34/18639 0.0882352941176471 1.59053931050176 0.291532823310921 0.819614702385274 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 3/1034 34/18639 0.0882352941176471 1.59053931050176 0.291532823310921 0.819614702385274 GO:0016831 carboxy-lyase activity 3/1034 34/18639 0.0882352941176471 1.59053931050176 0.291532823310921 0.819614702385274 GO:0015101 organic cation transmembrane transporter activity 6/1034 81/18639 0.0740740740740741 1.33526756931012 0.293188173699828 0.819614702385274 GO:0033192 calmodulin-dependent protein phosphatase activity 6/1034 81/18639 0.0740740740740741 1.33526756931012 0.293188173699828 0.819614702385274 GO:0140791 histone H2AXS140 phosphatase activity 6/1034 81/18639 0.0740740740740741 1.33526756931012 0.293188173699828 0.819614702385274 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 6/1034 81/18639 0.0740740740740741 1.33526756931012 0.293188173699828 0.819614702385274 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 6/1034 81/18639 0.0740740740740741 1.33526756931012 0.293188173699828 0.819614702385274 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 6/1034 81/18639 0.0740740740740741 1.33526756931012 0.293188173699828 0.819614702385274 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 6/1034 81/18639 0.0740740740740741 1.33526756931012 0.293188173699828 0.819614702385274 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 6/1034 81/18639 0.0740740740740741 1.33526756931012 0.293188173699828 0.819614702385274 GO:1990439 MAP kinase serine/threonine phosphatase activity 6/1034 81/18639 0.0740740740740741 1.33526756931012 0.293188173699828 0.819614702385274 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 22/1034 349/18639 0.0630372492836676 1.13631652746449 0.298070956245452 0.819614702385274 GO:0005007 fibroblast growth factor receptor activity 4/1034 50/18639 0.08 1.44208897485493 0.300622909680646 0.819614702385274 GO:0004725 protein tyrosine phosphatase activity 7/1034 98/18639 0.0714285714285714 1.28757944183476 0.301171768247687 0.819614702385274 GO:0042626 ATPase-coupled transmembrane transporter activity 7/1034 98/18639 0.0714285714285714 1.28757944183476 0.301171768247687 0.819614702385274 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 6/1034 82/18639 0.0731707317073171 1.31898381846488 0.302964796773288 0.819614702385274 GO:0033549 MAP kinase phosphatase activity 6/1034 82/18639 0.0731707317073171 1.31898381846488 0.302964796773288 0.819614702385274 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 12/1034 181/18639 0.0662983425414365 1.19510136037702 0.304113325211514 0.819614702385274 GO:0000339 RNA cap binding 2/1034 20/18639 0.1 1.80261121856867 0.305528836675937 0.819614702385274 GO:0005326 neurotransmitter transmembrane transporter activity 2/1034 20/18639 0.1 1.80261121856867 0.305528836675937 0.819614702385274 GO:0010851 cyclase regulator activity 2/1034 20/18639 0.1 1.80261121856867 0.305528836675937 0.819614702385274 GO:0016505 peptidase activator activity involved in apoptotic process 2/1034 20/18639 0.1 1.80261121856867 0.305528836675937 0.819614702385274 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/1034 20/18639 0.1 1.80261121856867 0.305528836675937 0.819614702385274 GO:0030742 GTP-dependent protein binding 2/1034 20/18639 0.1 1.80261121856867 0.305528836675937 0.819614702385274 GO:0031418 L-ascorbic acid binding 2/1034 20/18639 0.1 1.80261121856867 0.305528836675937 0.819614702385274 GO:0140664 ATP-dependent DNA damage sensor activity 2/1034 20/18639 0.1 1.80261121856867 0.305528836675937 0.819614702385274 GO:0035401 histone H3Y41 kinase activity 8/1034 115/18639 0.0695652173913043 1.25399041291733 0.30677719467023 0.819614702385274 GO:0140801 histone H2AXY142 kinase activity 8/1034 115/18639 0.0695652173913043 1.25399041291733 0.30677719467023 0.819614702385274 GO:0043015 gamma-tubulin binding 3/1034 35/18639 0.0857142857142857 1.54509533020171 0.306965962680416 0.819614702385274 GO:0061631 ubiquitin conjugating enzyme activity 3/1034 35/18639 0.0857142857142857 1.54509533020171 0.306965962680416 0.819614702385274 GO:0005179 hormone activity 9/1034 132/18639 0.0681818181818182 1.22905310356954 0.310791386016483 0.827727944529974 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 6/1034 83/18639 0.072289156626506 1.30309244715807 0.31279950256225 0.828210791066351 GO:0005048 signal sequence binding 4/1034 51/18639 0.0784313725490196 1.41381272044601 0.313334500802669 0.828210791066351 GO:0030544 Hsp70 protein binding 4/1034 51/18639 0.0784313725490196 1.41381272044601 0.313334500802669 0.828210791066351 GO:0017018 myosin phosphatase activity 6/1034 84/18639 0.0714285714285714 1.28757944183476 0.322684871048164 0.837370113575522 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 11/1034 167/18639 0.0658682634730539 1.18734870684164 0.322707060858387 0.837370113575522 GO:0019208 phosphatase regulator activity 8/1034 117/18639 0.0683760683760684 1.23255467936319 0.323401205424017 0.837370113575522 GO:0030145 manganese ion binding 5/1034 68/18639 0.0735294117647059 1.32544942541814 0.325339303073956 0.837370113575522 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/1034 21/18639 0.0952380952380952 1.71677258911301 0.326351470119738 0.837370113575522 GO:0001846 opsonin binding 2/1034 21/18639 0.0952380952380952 1.71677258911301 0.326351470119738 0.837370113575522 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/1034 21/18639 0.0952380952380952 1.71677258911301 0.326351470119738 0.837370113575522 GO:0036122 BMP binding 2/1034 21/18639 0.0952380952380952 1.71677258911301 0.326351470119738 0.837370113575522 GO:0051428 peptide hormone receptor binding 2/1034 21/18639 0.0952380952380952 1.71677258911301 0.326351470119738 0.837370113575522 GO:0061891 calcium ion sensor activity 2/1034 21/18639 0.0952380952380952 1.71677258911301 0.326351470119738 0.837370113575522 GO:0072542 protein phosphatase activator activity 2/1034 21/18639 0.0952380952380952 1.71677258911301 0.326351470119738 0.837370113575522 GO:1904047 S-adenosyl-L-methionine binding 2/1034 21/18639 0.0952380952380952 1.71677258911301 0.326351470119738 0.837370113575522 GO:0022829 wide pore channel activity 3/1034 37/18639 0.0810810810810811 1.46157666370432 0.337890901824357 0.862769972619474 GO:0042805 actinin binding 3/1034 37/18639 0.0810810810810811 1.46157666370432 0.337890901824357 0.862769972619474 GO:0004864 protein phosphatase inhibitor activity 4/1034 53/18639 0.0754716981132075 1.36046129703296 0.338880664070556 0.863202078940013 GO:0033691 sialic acid binding 2/1034 22/18639 0.0909090909090909 1.63873747142606 0.347003321732683 0.877518015535535 GO:0061133 endopeptidase activator activity 2/1034 22/18639 0.0909090909090909 1.63873747142606 0.347003321732683 0.877518015535535 GO:0140784 metal ion sensor activity 2/1034 22/18639 0.0909090909090909 1.63873747142606 0.347003321732683 0.877518015535535 GO:0016922 nuclear receptor binding 9/1034 137/18639 0.0656934306569343 1.18419715088452 0.349942193518453 0.878574364468251 GO:0015485 cholesterol binding 4/1034 54/18639 0.0740740740740741 1.33526756931012 0.351685234494154 0.878574364468251 GO:0000146 microfilament motor activity 3/1034 38/18639 0.0789473684210526 1.42311411992263 0.353332074209521 0.878574364468251 GO:0005501 retinoid binding 3/1034 38/18639 0.0789473684210526 1.42311411992263 0.353332074209521 0.878574364468251 GO:0019840 isoprenoid binding 3/1034 38/18639 0.0789473684210526 1.42311411992263 0.353332074209521 0.878574364468251 GO:0042887 amide transmembrane transporter activity 3/1034 38/18639 0.0789473684210526 1.42311411992263 0.353332074209521 0.878574364468251 GO:0008374 O-acyltransferase activity 4/1034 55/18639 0.0727272727272727 1.31098997714085 0.364491628670839 0.878574364468251 GO:0003887 DNA-directed DNA polymerase activity 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.878574364468251 GO:0005283 amino acid:sodium symporter activity 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.878574364468251 GO:0031681 G-protein beta-subunit binding 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.878574364468251 GO:0042171 lysophosphatidic acid acyltransferase activity 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.878574364468251 GO:0043274 phospholipase binding 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.878574364468251 GO:0071617 lysophospholipid acyltransferase activity 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.878574364468251 GO:0004713 protein tyrosine kinase activity 9/1034 140/18639 0.0642857142857143 1.15882149765128 0.373762475460661 0.878574364468251 GO:0170055 lipid transmembrane transporter activity 4/1034 56/18639 0.0714285714285714 1.28757944183476 0.377286122472127 0.878574364468251 GO:0004721 phosphoprotein phosphatase activity 11/1034 175/18639 0.0628571428571429 1.13306990881459 0.379199625843513 0.878574364468251 GO:0019888 protein phosphatase regulator activity 7/1034 107/18639 0.0654205607476635 1.17927836728791 0.382992067979006 0.878574364468251 GO:0030331 nuclear estrogen receptor binding 3/1034 40/18639 0.075 1.3519584139265 0.384055975761852 0.878574364468251 GO:0005315 phosphate transmembrane transporter activity 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.878574364468251 GO:0015295 solute:proton symporter activity 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.878574364468251 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.878574364468251 GO:0030215 semaphorin receptor binding 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.878574364468251 GO:0035035 histone acetyltransferase binding 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.878574364468251 GO:0050431 transforming growth factor beta binding 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.878574364468251 GO:0070840 dynein complex binding 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.878574364468251 GO:0140612 DNA damage sensor activity 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.878574364468251 GO:0072341 modified amino acid binding 6/1034 91/18639 0.0659340659340659 1.18853486938593 0.392696114876962 0.878574364468251 GO:0001530 lipopolysaccharide binding 3/1034 41/18639 0.0731707317073171 1.31898381846488 0.399296606496362 0.878574364468251 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/1034 41/18639 0.0731707317073171 1.31898381846488 0.399296606496362 0.878574364468251 GO:0015175 neutral L-amino acid transmembrane transporter activity 3/1034 41/18639 0.0731707317073171 1.31898381846488 0.399296606496362 0.878574364468251 GO:0042169 SH2 domain binding 3/1034 41/18639 0.0731707317073171 1.31898381846488 0.399296606496362 0.878574364468251 GO:0061650 ubiquitin-like protein conjugating enzyme activity 3/1034 41/18639 0.0731707317073171 1.31898381846488 0.399296606496362 0.878574364468251 GO:0052689 carboxylic ester hydrolase activity 6/1034 92/18639 0.0652173913043478 1.17561601211 0.402730926600584 0.878574364468251 GO:0008408 3'-5' exonuclease activity 4/1034 58/18639 0.0689655172413793 1.24318015073701 0.402787220896954 0.878574364468251 GO:0061980 regulatory RNA binding 4/1034 58/18639 0.0689655172413793 1.24318015073701 0.402787220896954 0.878574364468251 GO:0003725 double-stranded RNA binding 5/1034 75/18639 0.0666666666666667 1.20174081237911 0.40340887066357 0.878574364468251 GO:0001848 complement binding 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.878574364468251 GO:0005537 D-mannose binding 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.878574364468251 GO:0015662 P-type ion transporter activity 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.878574364468251 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.878574364468251 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.878574364468251 GO:0019211 phosphatase activator activity 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.878574364468251 GO:0042974 nuclear retinoic acid receptor binding 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.878574364468251 GO:0140358 P-type transmembrane transporter activity 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.878574364468251 GO:0042277 peptide binding 15/1034 249/18639 0.0602409638554217 1.08591037263173 0.409002177473864 0.878574364468251 GO:0051213 dioxygenase activity 6/1034 93/18639 0.0645161290322581 1.16297497972172 0.412754289257323 0.878574364468251 GO:0051219 phosphoprotein binding 6/1034 93/18639 0.0645161290322581 1.16297497972172 0.412754289257323 0.878574364468251 GO:0008307 structural constituent of muscle 3/1034 42/18639 0.0714285714285714 1.28757944183476 0.414430600177289 0.878574364468251 GO:0031492 nucleosomal DNA binding 3/1034 42/18639 0.0714285714285714 1.28757944183476 0.414430600177289 0.878574364468251 GO:0016741 transferase activity, transferring one-carbon groups 13/1034 215/18639 0.0604651162790698 1.0899509693671 0.41534135294154 0.878574364468251 GO:0016410 N-acyltransferase activity 6/1034 94/18639 0.0638297872340425 1.15060290546936 0.422760000996763 0.878574364468251 GO:0042562 hormone binding 6/1034 94/18639 0.0638297872340425 1.15060290546936 0.422760000996763 0.878574364468251 GO:0004529 DNA exonuclease activity 2/1034 26/18639 0.0769230769230769 1.38662401428359 0.427080736902809 0.878574364468251 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 2/1034 26/18639 0.0769230769230769 1.38662401428359 0.427080736902809 0.878574364468251 GO:0008143 poly(A) binding 2/1034 26/18639 0.0769230769230769 1.38662401428359 0.427080736902809 0.878574364468251 GO:0050681 nuclear androgen receptor binding 2/1034 26/18639 0.0769230769230769 1.38662401428359 0.427080736902809 0.878574364468251 GO:0070006 metalloaminopeptidase activity 2/1034 26/18639 0.0769230769230769 1.38662401428359 0.427080736902809 0.878574364468251 GO:0070412 R-SMAD binding 2/1034 26/18639 0.0769230769230769 1.38662401428359 0.427080736902809 0.878574364468251 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/1034 60/18639 0.0666666666666667 1.20174081237911 0.428089701307392 0.878574364468251 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 4/1034 60/18639 0.0666666666666667 1.20174081237911 0.428089701307392 0.878574364468251 GO:0004867 serine-type endopeptidase inhibitor activity 6/1034 95/18639 0.0631578947368421 1.1384912959381 0.432742027672682 0.878574364468251 GO:0016798 hydrolase activity, acting on glycosyl bonds 8/1034 130/18639 0.0615384615384615 1.10929921142687 0.433760333276528 0.878574364468251 GO:0000182 rDNA binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0004090 carbonyl reductase (NADPH) activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0004955 prostaglandin receptor activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0005528 FK506 binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0008239 dipeptidyl-peptidase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0008401 retinoic acid 4-hydroxylase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0015643 toxic substance binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0016427 tRNA (cytidine) methyltransferase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0016868 intramolecular phosphotransferase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0019911 structural constituent of myelin sheath 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0031419 cobalamin binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0032052 bile acid binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0032356 oxidized DNA binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0033204 ribonuclease P RNA binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0035374 chondroitin sulfate binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0042975 peroxisome proliferator activated receptor binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0051880 G-quadruplex DNA binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0070097 delta-catenin binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0140135 mechanosensitive monoatomic cation channel activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0141109 transporter activator activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:1990757 ubiquitin ligase activator activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.878574364468251 GO:0019199 transmembrane receptor protein kinase activity 5/1034 78/18639 0.0641025641025641 1.15552001190299 0.436676132487008 0.878574364468251 GO:0001046 core promoter sequence-specific DNA binding 3/1034 44/18639 0.0681818181818182 1.22905310356954 0.44430947544389 0.878574364468251 GO:0016790 thiolester hydrolase activity 3/1034 44/18639 0.0681818181818182 1.22905310356954 0.44430947544389 0.878574364468251 GO:0005385 zinc ion transmembrane transporter activity 2/1034 27/18639 0.0740740740740741 1.33526756931012 0.446305576552081 0.878574364468251 GO:0016791 phosphatase activity 16/1034 273/18639 0.0586080586080586 1.05647543945416 0.44719825814438 0.878574364468251 GO:0046332 SMAD binding 5/1034 79/18639 0.0632911392405063 1.14089317630928 0.447678632254605 0.878574364468251 GO:0042578 phosphoric ester hydrolase activity 21/1034 363/18639 0.0578512396694215 1.04283293636204 0.453517026613165 0.878574364468251 GO:0042605 peptide antigen binding 3/1034 45/18639 0.0666666666666667 1.20174081237911 0.459022998767057 0.878574364468251 GO:0046915 transition metal ion transmembrane transporter activity 3/1034 45/18639 0.0666666666666667 1.20174081237911 0.459022998767057 0.878574364468251 GO:0051539 4 iron, 4 sulfur cluster binding 3/1034 45/18639 0.0666666666666667 1.20174081237911 0.459022998767057 0.878574364468251 GO:0003714 transcription corepressor activity 12/1034 204/18639 0.0588235294117647 1.06035954033451 0.459743471809545 0.878574364468251 GO:0008168 methyltransferase activity 12/1034 204/18639 0.0588235294117647 1.06035954033451 0.459743471809545 0.878574364468251 GO:0045499 chemorepellent activity 2/1034 28/18639 0.0714285714285714 1.28757944183476 0.465162853056741 0.878574364468251 GO:0046875 ephrin receptor binding 2/1034 28/18639 0.0714285714285714 1.28757944183476 0.465162853056741 0.878574364468251 GO:0050698 proteoglycan sulfotransferase activity 2/1034 28/18639 0.0714285714285714 1.28757944183476 0.465162853056741 0.878574364468251 GO:0051019 mitogen-activated protein kinase binding 2/1034 28/18639 0.0714285714285714 1.28757944183476 0.465162853056741 0.878574364468251 GO:0051393 alpha-actinin binding 2/1034 28/18639 0.0714285714285714 1.28757944183476 0.465162853056741 0.878574364468251 GO:0003953 NAD+ nucleosidase activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0004016 adenylate cyclase activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0004954 prostanoid receptor activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0005536 D-glucose binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0008199 ferric iron binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0008271 secondary active sulfate transmembrane transporter activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0008432 JUN kinase binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0008503 benzodiazepine receptor activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0008526 phosphatidylinositol transfer activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0015173 aromatic amino acid transmembrane transporter activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0019206 nucleoside kinase activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0032050 clathrin heavy chain binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0032404 mismatch repair complex binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0032794 GTPase activating protein binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0034056 estrogen response element binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0042608 T cell receptor binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0047676 arachidonate-CoA ligase activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0050998 nitric-oxide synthase binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0097493 structural molecule activity conferring elasticity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0140537 transcription regulator activator activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.878574364468251 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 3/1034 46/18639 0.0652173913043478 1.17561601211 0.473567090829281 0.878574364468251 GO:0005416 amino acid:monoatomic cation symporter activity 2/1034 29/18639 0.0689655172413793 1.24318015073701 0.483634162901202 0.878574364468251 GO:0016779 nucleotidyltransferase activity 8/1034 136/18639 0.0588235294117647 1.06035954033451 0.484418930676922 0.878574364468251 GO:0140359 ABC-type transporter activity 3/1034 47/18639 0.0638297872340425 1.15060290546936 0.48792913551454 0.878574364468251 GO:0140938 histone H3 methyltransferase activity 3/1034 47/18639 0.0638297872340425 1.15060290546936 0.48792913551454 0.878574364468251 GO:0003730 mRNA 3'-UTR binding 15/1034 262/18639 0.0572519083969466 1.03202932360801 0.487984315415935 0.878574364468251 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0003995 acyl-CoA dehydrogenase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0004032 aldose reductase (NADPH) activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0004300 enoyl-CoA hydratase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0004526 ribonuclease P activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0004875 complement receptor activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0005025 transforming growth factor beta receptor activity, type I 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0005026 transforming growth factor beta receptor activity, type II 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0005095 GTPase inhibitor activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0005165 neurotrophin receptor binding 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0005527 macrolide binding 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0008603 cAMP-dependent protein kinase regulator activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0015368 calcium:monoatomic cation antiporter activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0016273 arginine N-methyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0016274 protein-arginine N-methyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0016361 activin receptor activity, type I 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0016362 activin receptor activity, type II 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0016840 carbon-nitrogen lyase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0017002 activin receptor activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0035251 UDP-glucosyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0042301 phosphate ion binding 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0097677 STAT family protein binding 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:1990817 poly(A) RNA polymerase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.878574364468251 GO:0015171 amino acid transmembrane transporter activity 6/1034 102/18639 0.0588235294117647 1.06035954033451 0.501483592318102 0.878574364468251 GO:0008106 alcohol dehydrogenase (NADP+) activity 2/1034 30/18639 0.0666666666666667 1.20174081237911 0.501704270848028 0.878574364468251 GO:0016769 transferase activity, transferring nitrogenous groups 2/1034 30/18639 0.0666666666666667 1.20174081237911 0.501704270848028 0.878574364468251 GO:0031210 phosphatidylcholine binding 2/1034 30/18639 0.0666666666666667 1.20174081237911 0.501704270848028 0.878574364468251 GO:0048019 receptor antagonist activity 2/1034 30/18639 0.0666666666666667 1.20174081237911 0.501704270848028 0.878574364468251 GO:0070566 adenylyltransferase activity 2/1034 30/18639 0.0666666666666667 1.20174081237911 0.501704270848028 0.878574364468251 GO:0004527 exonuclease activity 5/1034 84/18639 0.0595238095238095 1.07298286819563 0.501719594326508 0.878574364468251 GO:0140693 molecular condensate scaffold activity 3/1034 48/18639 0.0625 1.12663201160542 0.502097664076093 0.878574364468251 GO:0004722 protein serine/threonine phosphatase activity 6/1034 103/18639 0.058252427184466 1.05006478751573 0.511080529625036 0.878574364468251 GO:0016500 protein-hormone receptor activity 4/1034 67/18639 0.0597014925373134 1.07618580213055 0.513868505070908 0.878574364468251 GO:0042054 histone methyltransferase activity 4/1034 67/18639 0.0597014925373134 1.07618580213055 0.513868505070908 0.878574364468251 GO:0005004 GPI-linked ephrin receptor activity 3/1034 49/18639 0.0612244897959184 1.10363952157265 0.51606230960813 0.878574364468251 GO:0005008 hepatocyte growth factor receptor activity 3/1034 49/18639 0.0612244897959184 1.10363952157265 0.51606230960813 0.878574364468251 GO:0005009 insulin receptor activity 3/1034 49/18639 0.0612244897959184 1.10363952157265 0.51606230960813 0.878574364468251 GO:0005011 macrophage colony-stimulating factor receptor activity 3/1034 49/18639 0.0612244897959184 1.10363952157265 0.51606230960813 0.878574364468251 GO:0005018 platelet-derived growth factor alpha-receptor activity 3/1034 49/18639 0.0612244897959184 1.10363952157265 0.51606230960813 0.878574364468251 GO:0005020 stem cell factor receptor activity 3/1034 49/18639 0.0612244897959184 1.10363952157265 0.51606230960813 0.878574364468251 GO:0008288 boss receptor activity 3/1034 49/18639 0.0612244897959184 1.10363952157265 0.51606230960813 0.878574364468251 GO:0036332 placental growth factor receptor activity 3/1034 49/18639 0.0612244897959184 1.10363952157265 0.51606230960813 0.878574364468251 GO:0038062 protein tyrosine kinase collagen receptor activity 3/1034 49/18639 0.0612244897959184 1.10363952157265 0.51606230960813 0.878574364468251 GO:0060175 brain-derived neurotrophic factor receptor activity 3/1034 49/18639 0.0612244897959184 1.10363952157265 0.51606230960813 0.878574364468251 GO:0005310 dicarboxylic acid transmembrane transporter activity 2/1034 31/18639 0.0645161290322581 1.16297497972172 0.51936081564456 0.878574364468251 GO:0008327 methyl-CpG binding 2/1034 31/18639 0.0645161290322581 1.16297497972172 0.51936081564456 0.878574364468251 GO:0016411 acylglycerol O-acyltransferase activity 2/1034 31/18639 0.0645161290322581 1.16297497972172 0.51936081564456 0.878574364468251 GO:0047499 calcium-independent phospholipase A2 activity 2/1034 31/18639 0.0645161290322581 1.16297497972172 0.51936081564456 0.878574364468251 GO:0050660 flavin adenine dinucleotide binding 5/1034 86/18639 0.0581395348837209 1.0480297782376 0.522764674189108 0.878574364468251 GO:0002161 aminoacyl-tRNA editing activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0003964 RNA-directed DNA polymerase activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0005172 vascular endothelial growth factor receptor binding 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0008417 fucosyltransferase activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0009982 pseudouridine synthase activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0019855 calcium channel inhibitor activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0031432 titin binding 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0045159 myosin II binding 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0061459 L-arginine transmembrane transporter activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0070123 transforming growth factor beta receptor activity, type III 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0071837 HMG box domain binding 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0097157 pre-mRNA intronic binding 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.878574364468251 GO:0032934 sterol binding 4/1034 68/18639 0.0588235294117647 1.06035954033451 0.525651580195718 0.878574364468251 GO:0005006 epidermal growth factor receptor activity 3/1034 50/18639 0.06 1.0815667311412 0.529813760667331 0.878574364468251 GO:0005017 platelet-derived growth factor receptor activity 3/1034 50/18639 0.06 1.0815667311412 0.529813760667331 0.878574364468251 GO:0005019 platelet-derived growth factor beta-receptor activity 3/1034 50/18639 0.06 1.0815667311412 0.529813760667331 0.878574364468251 GO:0004674 protein serine/threonine kinase activity 24/1034 433/18639 0.0554272517321016 0.999137857867159 0.532151155582358 0.878574364468251 GO:0008081 phosphoric diester hydrolase activity 5/1034 87/18639 0.0574712643678161 1.03598345894751 0.533142281079602 0.878574364468251 GO:0030515 snoRNA binding 2/1034 32/18639 0.0625 1.12663201160542 0.53659403858032 0.878574364468251 GO:0031369 translation initiation factor binding 2/1034 32/18639 0.0625 1.12663201160542 0.53659403858032 0.878574364468251 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/1034 32/18639 0.0625 1.12663201160542 0.53659403858032 0.878574364468251 GO:0043425 bHLH transcription factor binding 2/1034 32/18639 0.0625 1.12663201160542 0.53659403858032 0.878574364468251 GO:0047498 calcium-dependent phospholipase A2 activity 2/1034 32/18639 0.0625 1.12663201160542 0.53659403858032 0.878574364468251 GO:0051059 NF-kappaB binding 2/1034 32/18639 0.0625 1.12663201160542 0.53659403858032 0.878574364468251 GO:0070717 poly-purine tract binding 2/1034 32/18639 0.0625 1.12663201160542 0.53659403858032 0.878574364468251 GO:0008080 N-acetyltransferase activity 4/1034 69/18639 0.0579710144927536 1.04499201076444 0.537294804422052 0.878574364468251 GO:0005125 cytokine activity 13/1034 234/18639 0.0555555555555556 1.00145067698259 0.538581527549087 0.878574364468251 GO:0004497 monooxygenase activity 6/1034 106/18639 0.0566037735849057 1.02034597277472 0.539436344334374 0.878574364468251 GO:0005010 insulin-like growth factor receptor activity 3/1034 51/18639 0.0588235294117647 1.06035954033451 0.543343714408873 0.878574364468251 GO:0005021 vascular endothelial growth factor receptor activity 3/1034 51/18639 0.0588235294117647 1.06035954033451 0.543343714408873 0.878574364468251 GO:0005030 neurotrophin receptor activity 3/1034 51/18639 0.0588235294117647 1.06035954033451 0.543343714408873 0.878574364468251 GO:0016782 transferase activity, transferring sulphur-containing groups 4/1034 70/18639 0.0571428571428571 1.03006355346781 0.548792110725933 0.878574364468251 GO:0005161 platelet-derived growth factor receptor binding 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.878574364468251 GO:0005545 1-phosphatidylinositol binding 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.878574364468251 GO:0008174 mRNA methyltransferase activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.878574364468251 GO:0008191 metalloendopeptidase inhibitor activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.878574364468251 GO:0008474 palmitoyl-(protein) hydrolase activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.878574364468251 GO:0016530 metallochaperone activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.878574364468251 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.878574364468251 GO:0030983 mismatched DNA binding 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.878574364468251 GO:0031404 chloride ion binding 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.878574364468251 GO:0032036 myosin heavy chain binding 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.878574364468251 GO:0042813 Wnt receptor activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.878574364468251 GO:0098599 palmitoyl hydrolase activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.878574364468251 GO:0098821 BMP receptor activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.878574364468251 GO:1901474 azole transmembrane transporter activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.878574364468251 GO:1901612 cardiolipin binding 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.878574364468251 GO:0019956 chemokine binding 2/1034 33/18639 0.0606060606060606 1.09249164761737 0.553396533269401 0.879710791657008 GO:0005080 protein kinase C binding 3/1034 52/18639 0.0576923076923077 1.03996801071269 0.556644829556513 0.879710791657008 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 3/1034 52/18639 0.0576923076923077 1.03996801071269 0.556644829556513 0.879710791657008 GO:0004519 endonuclease activity 7/1034 127/18639 0.0551181102362205 0.993565238581154 0.561969244879271 0.879710791657008 GO:0042826 histone deacetylase binding 7/1034 127/18639 0.0551181102362205 0.993565238581154 0.561969244879271 0.879710791657008 GO:0015293 symporter activity 8/1034 146/18639 0.0547945205479452 0.987732174558173 0.565743023153887 0.879710791657008 GO:0005003 ephrin receptor activity 3/1034 53/18639 0.0566037735849057 1.02034597277472 0.56971067948567 0.879710791657008 GO:0005005 transmembrane-ephrin receptor activity 3/1034 53/18639 0.0566037735849057 1.02034597277472 0.56971067948567 0.879710791657008 GO:0005246 calcium channel regulator activity 3/1034 53/18639 0.0566037735849057 1.02034597277472 0.56971067948567 0.879710791657008 GO:0008146 sulfotransferase activity 3/1034 53/18639 0.0566037735849057 1.02034597277472 0.56971067948567 0.879710791657008 GO:0017046 peptide hormone binding 3/1034 53/18639 0.0566037735849057 1.02034597277472 0.56971067948567 0.879710791657008 GO:0038064 collagen receptor activity 3/1034 53/18639 0.0566037735849057 1.02034597277472 0.56971067948567 0.879710791657008 GO:0140296 general transcription initiation factor binding 3/1034 53/18639 0.0566037735849057 1.02034597277472 0.56971067948567 0.879710791657008 GO:0051427 hormone receptor binding 2/1034 34/18639 0.0588235294117647 1.06035954033451 0.569763015141806 0.879710791657008 GO:0090482 vitamin transmembrane transporter activity 2/1034 34/18639 0.0588235294117647 1.06035954033451 0.569763015141806 0.879710791657008 GO:0008237 metallopeptidase activity 10/1034 184/18639 0.0543478260869565 0.979680010091666 0.572690026581763 0.879710791657008 GO:0000774 adenyl-nucleotide exchange factor activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.879710791657008 GO:0004089 carbonate dehydratase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.879710791657008 GO:0004559 alpha-mannosidase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.879710791657008 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.879710791657008 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.879710791657008 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.879710791657008 GO:0004953 icosanoid receptor activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.879710791657008 GO:0005523 tropomyosin binding 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.879710791657008 GO:0008242 omega peptidase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.879710791657008 GO:0015116 sulfate transmembrane transporter activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.879710791657008 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.879710791657008 GO:0033130 acetylcholine receptor binding 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.879710791657008 GO:0140161 monocarboxylate:sodium symporter activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.879710791657008 GO:0004521 RNA endonuclease activity 4/1034 73/18639 0.0547945205479452 0.987732174558173 0.582355156011642 0.883997123257323 GO:0003925 G protein activity 3/1034 54/18639 0.0555555555555556 1.00145067698259 0.582535705661642 0.883997123257323 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/1034 54/18639 0.0555555555555556 1.00145067698259 0.582535705661642 0.883997123257323 GO:0000175 3'-5'-RNA exonuclease activity 2/1034 35/18639 0.0571428571428571 1.03006355346781 0.585690109230375 0.883997123257323 GO:0004623 phospholipase A2 activity 2/1034 35/18639 0.0571428571428571 1.03006355346781 0.585690109230375 0.883997123257323 GO:0005154 epidermal growth factor receptor binding 2/1034 35/18639 0.0571428571428571 1.03006355346781 0.585690109230375 0.883997123257323 GO:0005343 organic acid:sodium symporter activity 2/1034 35/18639 0.0571428571428571 1.03006355346781 0.585690109230375 0.883997123257323 GO:0016229 steroid dehydrogenase activity 2/1034 35/18639 0.0571428571428571 1.03006355346781 0.585690109230375 0.883997123257323 GO:0034061 DNA polymerase activity 2/1034 35/18639 0.0571428571428571 1.03006355346781 0.585690109230375 0.883997123257323 GO:0016247 channel regulator activity 9/1034 168/18639 0.0535714285714286 0.965684581376071 0.591210160634364 0.886139206052183 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.886139206052183 GO:0004708 MAP kinase kinase activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.886139206052183 GO:0005024 transforming growth factor beta receptor activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.886139206052183 GO:0008296 3'-5'-DNA exonuclease activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.886139206052183 GO:0015378 sodium:chloride symporter activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.886139206052183 GO:0015923 mannosidase activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.886139206052183 GO:0016722 oxidoreductase activity, acting on metal ions 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.886139206052183 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.886139206052183 GO:0030275 LRR domain binding 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.886139206052183 GO:0034450 ubiquitin-ubiquitin ligase activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.886139206052183 GO:0043023 ribosomal large subunit binding 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.886139206052183 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.886139206052183 GO:0097027 ubiquitin-protein transferase activator activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.886139206052183 GO:0004033 aldo-keto reductase (NADPH) activity 2/1034 36/18639 0.0555555555555556 1.00145067698259 0.601176154935839 0.887008856931982 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/1034 36/18639 0.0555555555555556 1.00145067698259 0.601176154935839 0.887008856931982 GO:0141108 transporter regulator activity 9/1034 170/18639 0.0529411764705882 0.954323586301058 0.605516743565006 0.89104846642192 GO:0008276 protein methyltransferase activity 5/1034 95/18639 0.0526315789473684 0.948742746615087 0.612099462391 0.89104846642192 GO:0098631 cell adhesion mediator activity 4/1034 76/18639 0.0526315789473684 0.948742746615087 0.614432205166377 0.89104846642192 GO:0051015 actin filament binding 11/1034 209/18639 0.0526315789473684 0.948742746615087 0.614947979964974 0.89104846642192 GO:0030551 cyclic nucleotide binding 2/1034 37/18639 0.0540540540540541 0.974384442469549 0.61622102654221 0.89104846642192 GO:0043394 proteoglycan binding 2/1034 37/18639 0.0540540540540541 0.974384442469549 0.61622102654221 0.89104846642192 GO:0030695 GTPase regulator activity 26/1034 489/18639 0.0531697341513292 0.958443592694996 0.618010275732565 0.89104846642192 GO:0004549 tRNA-specific ribonuclease activity 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.89104846642192 GO:0004659 prenyltransferase activity 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.89104846642192 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.89104846642192 GO:0008429 phosphatidylethanolamine binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.89104846642192 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.89104846642192 GO:0017110 nucleoside diphosphate phosphatase activity 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.89104846642192 GO:0030548 acetylcholine receptor regulator activity 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.89104846642192 GO:0032183 SUMO binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.89104846642192 GO:0032977 membrane insertase activity 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.89104846642192 GO:0036041 long-chain fatty acid binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.89104846642192 GO:0045236 CXCR chemokine receptor binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.89104846642192 GO:1990226 histone methyltransferase binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.89104846642192 GO:0008094 ATP-dependent activity, acting on DNA 11/1034 210/18639 0.0523809523809524 0.944224924012158 0.621279747028716 0.89104846642192 GO:0060589 nucleoside-triphosphatase regulator activity 26/1034 490/18639 0.0530612244897959 0.956487585362965 0.622196969302387 0.89104846642192 GO:0035173 histone kinase activity 19/1034 360/18639 0.0527777777777778 0.951378143133462 0.622548120551437 0.89104846642192 GO:0001216 DNA-binding transcription activator activity 26/1034 491/18639 0.0529531568228106 0.954539545474242 0.626363722302831 0.895291624813286 GO:0015294 solute:monoatomic cation symporter activity 6/1034 116/18639 0.0517241379310345 0.932385113052758 0.62817095337434 0.895814882393252 GO:0005109 frizzled binding 2/1034 38/18639 0.0526315789473684 0.948742746615087 0.63082596833847 0.895814882393252 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 2/1034 38/18639 0.0526315789473684 0.948742746615087 0.63082596833847 0.895814882393252 GO:0008170 N-methyltransferase activity 5/1034 98/18639 0.0510204081632653 0.919699601310544 0.639618353047257 0.895814882393252 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.895814882393252 GO:0008308 voltage-gated monoatomic anion channel activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.895814882393252 GO:0008409 5'-3' exonuclease activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.895814882393252 GO:0015373 monoatomic anion:sodium symporter activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.895814882393252 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.895814882393252 GO:0016854 racemase and epimerase activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.895814882393252 GO:0017128 phospholipid scramblase activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.895814882393252 GO:0022851 GABA-gated chloride ion channel activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.895814882393252 GO:0035615 clathrin adaptor activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.895814882393252 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.895814882393252 GO:0070064 proline-rich region binding 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.895814882393252 GO:0070628 proteasome binding 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.895814882393252 GO:0099602 neurotransmitter receptor regulator activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.895814882393252 GO:1990381 ubiquitin-specific protease binding 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.895814882393252 GO:0004879 nuclear receptor activity 3/1034 59/18639 0.0508474576271186 0.916581975543389 0.642908969778427 0.895814882393252 GO:0015370 solute:sodium symporter activity 4/1034 79/18639 0.0506329113924051 0.912714541047426 0.644933014787066 0.897446470312161 GO:0004252 serine-type endopeptidase activity 9/1034 176/18639 0.0511363636363636 0.921789827677158 0.64687794053623 0.897907272665989 GO:0005096 GTPase activator activity 14/1034 271/18639 0.0516605166051661 0.931238267895251 0.646971209772642 0.897907272665989 GO:0001098 basal transcription machinery binding 3/1034 60/18639 0.05 0.901305609284333 0.654215247066376 0.898712886862558 GO:0001099 basal RNA polymerase II transcription machinery binding 3/1034 60/18639 0.05 0.901305609284333 0.654215247066376 0.898712886862558 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/1034 60/18639 0.05 0.901305609284333 0.654215247066376 0.898712886862558 GO:0098531 ligand-modulated transcription factor activity 3/1034 60/18639 0.05 0.901305609284333 0.654215247066376 0.898712886862558 GO:0043130 ubiquitin binding 5/1034 100/18639 0.05 0.901305609284333 0.657276173505106 0.898712886862558 GO:0004177 aminopeptidase activity 2/1034 40/18639 0.05 0.901305609284333 0.658726994202878 0.898712886862558 GO:0004532 RNA exonuclease activity 2/1034 40/18639 0.05 0.901305609284333 0.658726994202878 0.898712886862558 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/1034 40/18639 0.05 0.901305609284333 0.658726994202878 0.898712886862558 GO:0061791 GTPase motor activity 2/1034 40/18639 0.05 0.901305609284333 0.658726994202878 0.898712886862558 GO:0071855 neuropeptide receptor binding 2/1034 40/18639 0.05 0.901305609284333 0.658726994202878 0.898712886862558 GO:1990606 membrane scission GTPase motor activity 2/1034 40/18639 0.05 0.901305609284333 0.658726994202878 0.898712886862558 GO:0032182 ubiquitin-like protein binding 6/1034 120/18639 0.05 0.901305609284333 0.660744824669264 0.898712886862558 GO:0004890 GABA-A receptor activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.898712886862558 GO:0008381 mechanosensitive monoatomic ion channel activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.898712886862558 GO:0042800 histone H3K4 methyltransferase activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.898712886862558 GO:0043395 heparan sulfate proteoglycan binding 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.898712886862558 GO:0046527 glucosyltransferase activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.898712886862558 GO:0030971 receptor tyrosine kinase binding 4/1034 81/18639 0.0493827160493827 0.890178379540082 0.664360977431938 0.900654314765978 GO:0004540 RNA nuclease activity 6/1034 121/18639 0.0495867768595041 0.893856802596033 0.66860373977401 0.90436035088903 GO:0099106 ion channel regulator activity 8/1034 160/18639 0.05 0.901305609284333 0.668814023756336 0.90436035088903 GO:0140828 metal cation:monoatomic cation antiporter activity 2/1034 41/18639 0.0487804878048781 0.879322545643251 0.672031116649366 0.907543947002739 GO:0008238 exopeptidase activity 5/1034 102/18639 0.0490196078431373 0.883632950278758 0.674368360888202 0.909532712377422 GO:0001972 retinoic acid binding 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.912412565215325 GO:0015464 acetylcholine receptor activity 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.912412565215325 GO:0042288 MHC class I protein binding 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.912412565215325 GO:0052745 inositol phosphate phosphatase activity 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.912412565215325 GO:0140939 histone H4 methyltransferase activity 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.912412565215325 GO:0001540 amyloid-beta binding 4/1034 83/18639 0.0481927710843374 0.868728298105381 0.683051226329296 0.91421105610486 GO:0051879 Hsp90 protein binding 2/1034 42/18639 0.0476190476190476 0.858386294556507 0.68491114247297 0.915535605948621 GO:0140713 histone chaperone activity 8/1034 164/18639 0.0487804878048781 0.879322545643251 0.69537758963794 0.923228604962856 GO:0140996 histone H3 kinase activity 18/1034 357/18639 0.0504201680672269 0.908879606001008 0.696325956275224 0.923228604962856 GO:0008200 ion channel inhibitor activity 2/1034 43/18639 0.0465116279069767 0.838423822590077 0.697373133393152 0.923228604962856 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.923228604962856 GO:0009975 cyclase activity 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.923228604962856 GO:0015174 basic amino acid transmembrane transporter activity 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.923228604962856 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.923228604962856 GO:0051010 microtubule plus-end binding 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.923228604962856 GO:0140312 cargo adaptor activity 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.923228604962856 GO:0120013 lipid transfer activity 3/1034 65/18639 0.0461538461538462 0.831974408570153 0.706862264703383 0.932285881137132 GO:0016248 channel inhibitor activity 2/1034 44/18639 0.0454545454545455 0.81936873571303 0.709423783771688 0.932285881137132 GO:0043014 alpha-tubulin binding 2/1034 44/18639 0.0454545454545455 0.81936873571303 0.709423783771688 0.932285881137132 GO:0005243 gap junction channel activity 1/1034 22/18639 0.0454545454545455 0.81936873571303 0.715305623558155 0.932285881137132 GO:0008649 rRNA methyltransferase activity 1/1034 22/18639 0.0454545454545455 0.81936873571303 0.715305623558155 0.932285881137132 GO:0015377 chloride:monoatomic cation symporter activity 1/1034 22/18639 0.0454545454545455 0.81936873571303 0.715305623558155 0.932285881137132 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/1034 22/18639 0.0454545454545455 0.81936873571303 0.715305623558155 0.932285881137132 GO:0016881 acid-amino acid ligase activity 1/1034 22/18639 0.0454545454545455 0.81936873571303 0.715305623558155 0.932285881137132 GO:0031683 G-protein beta/gamma-subunit complex binding 1/1034 22/18639 0.0454545454545455 0.81936873571303 0.715305623558155 0.932285881137132 GO:0008235 metalloexopeptidase activity 3/1034 66/18639 0.0454545454545455 0.81936873571303 0.716619889148815 0.932285881137132 GO:0005516 calmodulin binding 10/1034 207/18639 0.0483091787439614 0.870826675637036 0.717931259934696 0.932285881137132 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/1034 45/18639 0.0444444444444444 0.801160541586074 0.721070331911438 0.932285881137132 GO:0008009 chemokine activity 2/1034 45/18639 0.0444444444444444 0.801160541586074 0.721070331911438 0.932285881137132 GO:0141110 transporter inhibitor activity 2/1034 45/18639 0.0444444444444444 0.801160541586074 0.721070331911438 0.932285881137132 GO:0140597 protein carrier chaperone 9/1034 188/18639 0.0478723404255319 0.862952179102021 0.721779765506996 0.932285881137132 GO:0005496 steroid binding 5/1034 108/18639 0.0462962962962963 0.834542230818827 0.722175858487566 0.932285881137132 GO:0004518 nuclease activity 10/1034 209/18639 0.0478468899521531 0.862493406013715 0.728907420379794 0.932285881137132 GO:0004620 phospholipase activity 5/1034 109/18639 0.0458715596330275 0.826885880077369 0.729633428026593 0.932285881137132 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.932285881137132 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.932285881137132 GO:0005212 structural constituent of eye lens 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.932285881137132 GO:0016493 C-C chemokine receptor activity 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.932285881137132 GO:0016849 phosphorus-oxygen lyase activity 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.932285881137132 GO:0016917 GABA receptor activity 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.932285881137132 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.932285881137132 GO:0070577 lysine-acetylated histone binding 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.932285881137132 GO:0099186 structural constituent of postsynapse 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.932285881137132 GO:0140102 catalytic activity, acting on a rRNA 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.932285881137132 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.932285881137132 GO:0030276 clathrin binding 2/1034 46/18639 0.0434782608695652 0.783744008073333 0.732320479233354 0.932689036505434 GO:1990841 promoter-specific chromatin binding 3/1034 68/18639 0.0441176470588235 0.795269655250882 0.735376427050471 0.933230856403187 GO:0004222 metalloendopeptidase activity 5/1034 110/18639 0.0454545454545455 0.81936873571303 0.736945188502925 0.933230856403187 GO:0061733 protein-lysine-acetyltransferase activity 2/1034 47/18639 0.0425531914893617 0.767068603646241 0.743182316731968 0.933230856403187 GO:0016279 protein-lysine N-methyltransferase activity 3/1034 69/18639 0.0434782608695652 0.783744008073333 0.744380137169945 0.933230856403187 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 24/1034 484/18639 0.0495867768595041 0.893856802596033 0.744871089133175 0.933230856403187 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.933230856403187 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.933230856403187 GO:0015149 hexose transmembrane transporter activity 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.933230856403187 GO:0019957 C-C chemokine binding 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.933230856403187 GO:0030552 cAMP binding 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.933230856403187 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.933230856403187 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.933230856403187 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.933230856403187 GO:0055056 D-glucose transmembrane transporter activity 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.933230856403187 GO:0140033 acetylation-dependent protein binding 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.933230856403187 GO:0016278 lysine N-methyltransferase activity 3/1034 70/18639 0.0428571428571429 0.772547665100857 0.753137809995796 0.939401421298202 GO:0008188 neuropeptide receptor activity 2/1034 48/18639 0.0416666666666667 0.751088007736944 0.753664258151789 0.939401421298202 GO:0038187 pattern recognition receptor activity 2/1034 48/18639 0.0416666666666667 0.751088007736944 0.753664258151789 0.939401421298202 GO:0008236 serine-type peptidase activity 9/1034 194/18639 0.0463917525773196 0.836262936449381 0.755026100959164 0.939610264701736 GO:0004709 MAP kinase kinase kinase activity 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.939610264701736 GO:0008483 transaminase activity 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.939610264701736 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.939610264701736 GO:0047617 fatty acyl-CoA hydrolase activity 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.939610264701736 GO:0001222 transcription corepressor binding 2/1034 49/18639 0.0408163265306122 0.735759681048435 0.763774979366413 0.939610264701736 GO:0016763 pentosyltransferase activity 2/1034 49/18639 0.0408163265306122 0.735759681048435 0.763774979366413 0.939610264701736 GO:0060590 ATPase regulator activity 2/1034 49/18639 0.0408163265306122 0.735759681048435 0.763774979366413 0.939610264701736 GO:0141003 histone H2AX kinase activity 17/1034 354/18639 0.0480225988700565 0.865660754679868 0.764332576223835 0.939610264701736 GO:0051020 GTPase binding 15/1034 315/18639 0.0476190476190476 0.858386294556507 0.76493306471874 0.939610264701736 GO:0001664 G protein-coupled receptor binding 14/1034 297/18639 0.0471380471380471 0.849715725924623 0.771897835619888 0.939610264701736 GO:0001637 G protein-coupled chemoattractant receptor activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.939610264701736 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.939610264701736 GO:0004435 phosphatidylinositol phospholipase C activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.939610264701736 GO:0004950 chemokine receptor activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.939610264701736 GO:0005112 Notch binding 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.939610264701736 GO:0008157 protein phosphatase 1 binding 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.939610264701736 GO:0008198 ferrous iron binding 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.939610264701736 GO:0015145 monosaccharide transmembrane transporter activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.939610264701736 GO:0016289 acyl-CoA hydrolase activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.939610264701736 GO:0051139 metal cation:proton antiporter activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.939610264701736 GO:0097602 cullin family protein binding 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.939610264701736 GO:0017171 serine hydrolase activity 9/1034 198/18639 0.0454545454545455 0.81936873571303 0.77559520743073 0.941091301288498 GO:0140658 ATP-dependent chromatin remodeler activity 7/1034 158/18639 0.0443037974683544 0.798625223416497 0.779861320960756 0.941845704517399 GO:0016597 amino acid binding 2/1034 51/18639 0.0392156862745098 0.706906360223006 0.782918451196018 0.941845704517399 GO:1990782 protein tyrosine kinase binding 5/1034 117/18639 0.0427350427350427 0.770346674601994 0.784090480853915 0.941845704517399 GO:0003678 DNA helicase activity 3/1034 74/18639 0.0405405405405405 0.730788331852162 0.785772620461576 0.941845704517399 GO:0001671 ATPase activator activity 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.941845704517399 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.941845704517399 GO:0005044 scavenger receptor activity 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.941845704517399 GO:0015252 proton channel activity 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.941845704517399 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.941845704517399 GO:0023026 MHC class II protein complex binding 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.941845704517399 GO:0035255 ionotropic glutamate receptor binding 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.941845704517399 GO:0106310 protein serine kinase activity 17/1034 361/18639 0.0470914127423823 0.848875089076657 0.790529472932549 0.946117184897659 GO:0030159 signaling receptor complex adaptor activity 2/1034 52/18639 0.0384615384615385 0.693312007141794 0.791969396061598 0.946763414382728 GO:0019003 GDP binding 3/1034 75/18639 0.04 0.721044487427466 0.79335017880916 0.947337557442947 GO:0019789 SUMO transferase activity 1/1034 28/18639 0.0357142857142857 0.643789720917381 0.797950411154769 0.948524104559115 GO:0046966 nuclear thyroid hormone receptor binding 1/1034 28/18639 0.0357142857142857 0.643789720917381 0.797950411154769 0.948524104559115 GO:0051119 sugar transmembrane transporter activity 1/1034 28/18639 0.0357142857142857 0.643789720917381 0.797950411154769 0.948524104559115 GO:0097718 disordered domain specific binding 1/1034 28/18639 0.0357142857142857 0.643789720917381 0.797950411154769 0.948524104559115 GO:0005544 calcium-dependent phospholipid binding 2/1034 53/18639 0.0377358490566038 0.680230648516478 0.800685424162615 0.949629161464567 GO:0034212 protein N-acetyltransferase activity 2/1034 53/18639 0.0377358490566038 0.680230648516478 0.800685424162615 0.949629161464567 GO:0004181 metallocarboxypeptidase activity 1/1034 29/18639 0.0344827586206897 0.621590075368505 0.809175991449539 0.957540093368858 GO:0106222 lncRNA binding 1/1034 29/18639 0.0344827586206897 0.621590075368505 0.809175991449539 0.957540093368858 GO:0008528 G protein-coupled peptide receptor activity 5/1034 122/18639 0.040983606557377 0.738775089577322 0.813563749611699 0.961650634372481 GO:0098632 cell-cell adhesion mediator activity 2/1034 55/18639 0.0363636363636364 0.655494988570424 0.817149783849575 0.963723736109589 GO:0140313 molecular sequestering activity 2/1034 55/18639 0.0363636363636364 0.655494988570424 0.817149783849575 0.963723736109589 GO:0098918 structural constituent of synapse 1/1034 30/18639 0.0333333333333333 0.600870406189555 0.819778464573729 0.965741259497831 GO:0003924 GTPase activity 15/1034 331/18639 0.0453172205438066 0.816893301466162 0.824499364547611 0.970216254478844 GO:0005164 tumor necrosis factor receptor binding 1/1034 31/18639 0.032258064516129 0.58148748986086 0.829792386204702 0.973179030420676 GO:0005184 neuropeptide hormone activity 1/1034 31/18639 0.032258064516129 0.58148748986086 0.829792386204702 0.973179030420676 GO:0005452 solute:inorganic anion antiporter activity 1/1034 31/18639 0.032258064516129 0.58148748986086 0.829792386204702 0.973179030420676 GO:0160041 neuropeptide activity 1/1034 32/18639 0.03125 0.563316005802708 0.839250397418391 0.981549146157066 GO:0017116 single-stranded DNA helicase activity 2/1034 58/18639 0.0344827586206897 0.621590075368505 0.839565552759893 0.981549146157066 GO:0019783 ubiquitin-like protein peptidase activity 5/1034 127/18639 0.0393700787401575 0.709689456129396 0.839728356978479 0.981549146157066 GO:0001653 peptide receptor activity 5/1034 128/18639 0.0390625 0.704145007253385 0.844582652774207 0.981788318077472 GO:0031490 chromatin DNA binding 5/1034 128/18639 0.0390625 0.704145007253385 0.844582652774207 0.981788318077472 GO:0030165 PDZ domain binding 3/1034 83/18639 0.036144578313253 0.651546223579036 0.846232107194656 0.981788318077472 GO:0008013 beta-catenin binding 4/1034 106/18639 0.0377358490566038 0.680230648516478 0.846263428021007 0.981788318077472 GO:0015459 potassium channel regulator activity 2/1034 59/18639 0.0338983050847458 0.611054650362259 0.846465783741699 0.981788318077472 GO:0036002 pre-mRNA binding 2/1034 59/18639 0.0338983050847458 0.611054650362259 0.846465783741699 0.981788318077472 GO:0070063 RNA polymerase binding 2/1034 59/18639 0.0338983050847458 0.611054650362259 0.846465783741699 0.981788318077472 GO:0140311 protein sequestering activity 1/1034 33/18639 0.0303030303030303 0.546245823808687 0.848183330673047 0.982696986638817 GO:0016298 lipase activity 5/1034 130/18639 0.0384615384615385 0.693312007141794 0.853927266984817 0.9882634597008 GO:0008175 tRNA methyltransferase activity 1/1034 34/18639 0.0294117647058824 0.530179770167255 0.85662030993157 0.989203694893536 GO:0015020 glucuronosyltransferase activity 1/1034 34/18639 0.0294117647058824 0.530179770167255 0.85662030993157 0.989203694893536 GO:0015026 coreceptor activity 2/1034 61/18639 0.0327868852459016 0.591020071661858 0.859462325073929 0.98922665973041 GO:0019905 syntaxin binding 2/1034 61/18639 0.0327868852459016 0.591020071661858 0.859462325073929 0.98922665973041 GO:0016758 hexosyltransferase activity 8/1034 197/18639 0.0406091370558376 0.732024860332453 0.860854414091282 0.98922665973041 GO:0140566 histone reader activity 1/1034 35/18639 0.0285714285714286 0.515031776733904 0.864588845246311 0.98922665973041 GO:0004386 helicase activity 6/1034 155/18639 0.0387096774193548 0.697784987833032 0.866071887413187 0.98922665973041 GO:1902936 phosphatidylinositol bisphosphate binding 4/1034 111/18639 0.036036036036036 0.649589628313032 0.870413434738208 0.98922665973041 GO:0022824 transmitter-gated monoatomic ion channel activity 2/1034 63/18639 0.0317460317460317 0.572257529704338 0.871444832161361 0.98922665973041 GO:0022835 transmitter-gated channel activity 2/1034 63/18639 0.0317460317460317 0.572257529704338 0.871444832161361 0.98922665973041 GO:0004190 aspartic-type endopeptidase activity 1/1034 36/18639 0.0277777777777778 0.500725338491296 0.872114922112324 0.98922665973041 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/1034 36/18639 0.0277777777777778 0.500725338491296 0.872114922112324 0.98922665973041 GO:0004197 cysteine-type endopeptidase activity 3/1034 88/18639 0.0340909090909091 0.614526551784772 0.872959878094084 0.98922665973041 GO:0046982 protein heterodimerization activity 16/1034 369/18639 0.043360433604336 0.781620040571779 0.875897016664676 0.98922665973041 GO:0019213 deacetylase activity 1/1034 37/18639 0.027027027027027 0.487192221234774 0.879223085878161 0.98922665973041 GO:0023023 MHC protein complex binding 1/1034 37/18639 0.027027027027027 0.487192221234774 0.879223085878161 0.98922665973041 GO:0070001 aspartic-type peptidase activity 1/1034 37/18639 0.027027027027027 0.487192221234774 0.879223085878161 0.98922665973041 GO:0160215 deacylase activity 2/1034 65/18639 0.0307692307692308 0.554649605713435 0.882480594596268 0.98922665973041 GO:0035402 histone H3T11 kinase activity 10/1034 247/18639 0.0404858299595142 0.729802112780836 0.884319399517869 0.98922665973041 GO:0035403 histone H3T6 kinase activity 10/1034 247/18639 0.0404858299595142 0.729802112780836 0.884319399517869 0.98922665973041 GO:0043531 ADP binding 1/1034 38/18639 0.0263157894736842 0.474371373307544 0.885936521487342 0.98922665973041 GO:0101005 deubiquitinase activity 4/1034 115/18639 0.0347826086956522 0.626995206458666 0.887311366230507 0.98922665973041 GO:0070851 growth factor receptor binding 5/1034 139/18639 0.0359712230215827 0.648421301643405 0.890359436688639 0.98922665973041 GO:0008173 RNA methyltransferase activity 2/1034 67/18639 0.0298507462686567 0.538092901065273 0.892634199529625 0.98922665973041 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/1034 67/18639 0.0298507462686567 0.538092901065273 0.892634199529625 0.98922665973041 GO:1901981 phosphatidylinositol phosphate binding 7/1034 185/18639 0.0378378378378378 0.682069109728684 0.893546662032061 0.98922665973041 GO:0005085 guanyl-nucleotide exchange factor activity 9/1034 230/18639 0.0391304347826087 0.705369607266 0.896859820664443 0.98922665973041 GO:0140223 general transcription initiation factor activity 2/1034 68/18639 0.0294117647058824 0.530179770167255 0.897399586574448 0.98922665973041 GO:0015144 carbohydrate transmembrane transporter activity 1/1034 40/18639 0.025 0.450652804642166 0.898265593798455 0.98922665973041 GO:0032451 demethylase activity 1/1034 40/18639 0.025 0.450652804642166 0.898265593798455 0.98922665973041 GO:0019001 guanyl nucleotide binding 17/1034 400/18639 0.0425 0.766109767891683 0.899522988498855 0.98922665973041 GO:0032561 guanyl ribonucleotide binding 17/1034 400/18639 0.0425 0.766109767891683 0.899522988498855 0.98922665973041 GO:0008234 cysteine-type peptidase activity 7/1034 187/18639 0.0374331550802139 0.674774252940142 0.899528191639357 0.98922665973041 GO:0015103 inorganic anion transmembrane transporter activity 6/1034 165/18639 0.0363636363636364 0.655494988570424 0.900937759216402 0.98922665973041 GO:0003779 actin binding 19/1034 443/18639 0.0428893905191874 0.773128965074597 0.903028237147709 0.98922665973041 GO:0004812 aminoacyl-tRNA ligase activity 1/1034 41/18639 0.024390243902439 0.439661272821626 0.903921455727182 0.98922665973041 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/1034 41/18639 0.024390243902439 0.439661272821626 0.903921455727182 0.98922665973041 GO:0042287 MHC protein binding 1/1034 41/18639 0.024390243902439 0.439661272821626 0.903921455727182 0.98922665973041 GO:0004896 cytokine receptor activity 3/1034 96/18639 0.03125 0.563316005802708 0.907220856324584 0.98922665973041 GO:0019902 phosphatase binding 7/1034 190/18639 0.0368421052631579 0.664119922630561 0.907964016964263 0.98922665973041 GO:0008375 acetylglucosaminyltransferase activity 1/1034 43/18639 0.0232558139534884 0.419211911295038 0.914308171572494 0.98922665973041 GO:0048156 tau protein binding 1/1034 43/18639 0.0232558139534884 0.419211911295038 0.914308171572494 0.98922665973041 GO:0042379 chemokine receptor binding 2/1034 72/18639 0.0277777777777778 0.500725338491296 0.914556106381344 0.98922665973041 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/1034 73/18639 0.0273972602739726 0.493866087279086 0.918403705366879 0.98922665973041 GO:0008509 monoatomic anion transmembrane transporter activity 5/1034 149/18639 0.0335570469798658 0.604903093479418 0.921394585590271 0.98922665973041 GO:0035091 phosphatidylinositol binding 11/1034 284/18639 0.0387323943661972 0.698194486065328 0.921461062241101 0.98922665973041 GO:0000510 H3-H4 histone complex chaperone activity 5/1034 151/18639 0.033112582781457 0.596891131976379 0.926576384956348 0.98922665973041 GO:0140584 chromatin extrusion motor activity 5/1034 151/18639 0.033112582781457 0.596891131976379 0.926576384956348 0.98922665973041 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 5/1034 151/18639 0.033112582781457 0.596891131976379 0.926576384956348 0.98922665973041 GO:0140849 ATP-dependent H2AZ histone chaperone activity 5/1034 151/18639 0.033112582781457 0.596891131976379 0.926576384956348 0.98922665973041 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 9/1034 243/18639 0.037037037037037 0.667633784655061 0.927366214990252 0.98922665973041 GO:0004180 carboxypeptidase activity 1/1034 46/18639 0.0217391304347826 0.391872004036666 0.927823039360876 0.98922665973041 GO:0017022 myosin binding 2/1034 76/18639 0.0263157894736842 0.474371373307544 0.928990962836153 0.98922665973041 GO:0015616 DNA translocase activity 5/1034 152/18639 0.0328947368421053 0.592964216634429 0.929051666645726 0.98922665973041 GO:0140674 ATP-dependent histone chaperone activity 5/1034 152/18639 0.0328947368421053 0.592964216634429 0.929051666645726 0.98922665973041 GO:0016757 glycosyltransferase activity 10/1034 267/18639 0.0374531835205993 0.675135287853433 0.930886497950515 0.98922665973041 GO:0004676 3-phosphoinositide-dependent protein kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:0004711 ribosomal protein S6 kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:0035175 histone H3S10 kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:0035979 histone H2AXS139 kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:0044022 histone H3S28 kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:0044023 histone H4S1 kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:0044024 histone H2AS1 kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:0044025 histone H2BS14 kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:0072354 histone H3T3 kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:0072371 histone H2AS121 kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:0072518 Rho-dependent protein serine/threonine kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:0140823 histone H2BS36 kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:0140855 histone H3S57 kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:0140995 histone H2A kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:0140997 histone H4 kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:0140998 histone H2B kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:1990244 histone H2AT120 kinase activity 9/1034 245/18639 0.036734693877551 0.662183712943591 0.93129244768107 0.98922665973041 GO:0061775 cohesin loader activity 5/1034 153/18639 0.0326797385620915 0.589088633519172 0.931452348167526 0.98922665973041 GO:0043495 protein-membrane adaptor activity 1/1034 47/18639 0.0212765957446809 0.38353430182312 0.931836968113679 0.98922665973041 GO:0061749 forked DNA-dependent helicase activity 1/1034 47/18639 0.0212765957446809 0.38353430182312 0.931836968113679 0.98922665973041 GO:0099095 ligand-gated monoatomic anion channel activity 1/1034 47/18639 0.0212765957446809 0.38353430182312 0.931836968113679 0.98922665973041 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/1034 47/18639 0.0212765957446809 0.38353430182312 0.931836968113679 0.98922665973041 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 10/1034 268/18639 0.0373134328358209 0.672616126331592 0.932716817128858 0.98922665973041 GO:0004677 DNA-dependent protein kinase activity 9/1034 246/18639 0.0365853658536585 0.659491909232439 0.933185750460109 0.98922665973041 GO:0140857 histone H3T45 kinase activity 9/1034 246/18639 0.0365853658536585 0.659491909232439 0.933185750460109 0.98922665973041 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 4/1034 130/18639 0.0307692307692308 0.554649605713435 0.934686524629612 0.98922665973041 GO:0005525 GTP binding 15/1034 378/18639 0.0396825396825397 0.715321912130423 0.93505509618752 0.98922665973041 GO:0009378 four-way junction helicase activity 1/1034 48/18639 0.0208333333333333 0.375544003868472 0.935627876836272 0.98922665973041 GO:0036121 double-stranded DNA helicase activity 1/1034 48/18639 0.0208333333333333 0.375544003868472 0.935627876836272 0.98922665973041 GO:0043138 3'-5' DNA helicase activity 1/1034 48/18639 0.0208333333333333 0.375544003868472 0.935627876836272 0.98922665973041 GO:0004679 AMP-activated protein kinase activity 9/1034 248/18639 0.0362903225806452 0.654173426093467 0.936836947553278 0.989510510869527 GO:0000149 SNARE binding 3/1034 106/18639 0.0283018867924528 0.510172986387358 0.938195365487735 0.989951378628984 GO:0035254 glutamate receptor binding 1/1034 49/18639 0.0204081632653061 0.367879840524217 0.939208145533561 0.990027023147601 GO:0032813 tumor necrosis factor receptor superfamily binding 1/1034 50/18639 0.02 0.360522243713733 0.942589467616309 0.991160351403723 GO:0004175 endopeptidase activity 16/1034 405/18639 0.0395061728395062 0.712142703632065 0.942947763830716 0.991160351403723 GO:0004843 cysteine-type deubiquitinase activity 3/1034 108/18639 0.0277777777777778 0.500725338491296 0.943109802048599 0.991160351403723 GO:0003689 DNA clamp loader activity 5/1034 160/18639 0.03125 0.563316005802708 0.946318832048882 0.993540330654116 GO:0001217 DNA-binding transcription repressor activity 10/1034 278/18639 0.0359712230215827 0.648421301643405 0.948830915478303 0.994173611412715 GO:0005543 phospholipid binding 20/1034 497/18639 0.0402414486921529 0.725396868639302 0.951092890880016 0.994173611412715 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/1034 53/18639 0.0188679245283019 0.340115324258239 0.951647173662171 0.994173611412715 GO:0051018 protein kinase A binding 1/1034 53/18639 0.0188679245283019 0.340115324258239 0.951647173662171 0.994173611412715 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/1034 53/18639 0.0188679245283019 0.340115324258239 0.951647173662171 0.994173611412715 GO:0140101 catalytic activity, acting on a tRNA 4/1034 139/18639 0.0287769784172662 0.518737041314724 0.953593600127757 0.995218717593651 GO:0031267 small GTPase binding 10/1034 283/18639 0.0353356890459364 0.636965094900589 0.955535776253384 0.99538671123403 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/1034 86/18639 0.0232558139534884 0.419211911295038 0.955646937591607 0.99538671123403 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/1034 56/18639 0.0178571428571429 0.32189486045869 0.959276999754532 0.998179430011639 GO:0019903 protein phosphatase binding 4/1034 144/18639 0.0277777777777778 0.500725338491296 0.961779006101913 0.999793986580249 GO:0008194 UDP-glycosyltransferase activity 4/1034 145/18639 0.0275862068965517 0.497272060294804 0.96324641644112 0.999999855387334 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/1034 91/18639 0.021978021978022 0.396178289795311 0.965078923397083 0.999999855387334 GO:0001786 phosphatidylserine binding 1/1034 59/18639 0.0169491525423729 0.30552732518113 0.96570385736147 0.999999855387334 GO:0140098 catalytic activity, acting on RNA 14/1034 387/18639 0.0361757105943152 0.65210741757006 0.969652744585382 0.999999855387334 GO:0030594 neurotransmitter receptor activity 2/1034 97/18639 0.0206185567010309 0.371672416199725 0.973865324490681 0.999999855387334 GO:0030527 structural constituent of chromatin 2/1034 98/18639 0.0204081632653061 0.367879840524217 0.975104925820218 0.999999855387334 GO:0140375 immune receptor activity 4/1034 156/18639 0.0256410256410256 0.462208004761196 0.976273550902521 0.999999855387334 GO:0035591 signaling adaptor activity 3/1034 129/18639 0.0232558139534884 0.419211911295038 0.976814139771697 0.999999855387334 GO:0005253 monoatomic anion channel activity 2/1034 103/18639 0.0194174757281553 0.350021595838576 0.98049737474235 0.999999855387334 GO:0002039 p53 binding 1/1034 69/18639 0.0144927536231884 0.261248002691111 0.980657730832478 0.999999855387334 GO:0098960 postsynaptic neurotransmitter receptor activity 1/1034 69/18639 0.0144927536231884 0.261248002691111 0.980657730832478 0.999999855387334 GO:0015081 sodium ion transmembrane transporter activity 4/1034 164/18639 0.024390243902439 0.439661272821626 0.982870762084161 0.999999855387334 GO:0035064 methylated histone binding 1/1034 74/18639 0.0135135135135135 0.243596110617387 0.985475981422689 0.999999855387334 GO:0005126 cytokine receptor binding 8/1034 275/18639 0.0290909090909091 0.524395990856339 0.986993625656539 0.999999855387334 GO:0140034 methylation-dependent protein binding 1/1034 76/18639 0.0131578947368421 0.237185686653772 0.987048833453168 0.999999855387334 GO:0003724 RNA helicase activity 1/1034 77/18639 0.012987012987013 0.234105353060866 0.987770241965231 0.999999855387334 GO:0003823 antigen binding 4/1034 174/18639 0.0229885057471264 0.414393383579004 0.988692443961128 0.999999855387334 GO:0008186 ATP-dependent activity, acting on RNA 1/1034 79/18639 0.0126582278481013 0.228178635261856 0.989094849168862 0.999999855387334 GO:0015085 calcium ion transmembrane transporter activity 3/1034 147/18639 0.0204081632653061 0.367879840524217 0.989612007755754 0.999999855387334 GO:0005254 chloride channel activity 1/1034 83/18639 0.0120481927710843 0.217182074526345 0.991329528112657 0.999999855387334 GO:0015108 chloride transmembrane transporter activity 2/1034 121/18639 0.0165289256198347 0.297952267532011 0.992014628025093 0.999999855387334 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/1034 122/18639 0.0163934426229508 0.295510035830929 0.992405460661408 0.999999855387334 GO:0061630 ubiquitin protein ligase activity 10/1034 353/18639 0.028328611898017 0.510654736138432 0.99498627394885 0.999999855387334 GO:0140767 enzyme-substrate adaptor activity 2/1034 139/18639 0.0143884892086331 0.259368520657362 0.996789292479806 0.999999855387334 GO:0140030 modification-dependent protein binding 3/1034 173/18639 0.0173410404624277 0.312591540792254 0.996877260678545 0.999999855387334 GO:0061659 ubiquitin-like protein ligase activity 10/1034 372/18639 0.0268817204301075 0.484572908217383 0.997388094493616 0.999999855387334 GO:0004842 ubiquitin-protein transferase activity 13/1034 449/18639 0.0289532293986637 0.521914161278233 0.997542559841462 0.999999855387334 GO:0022834 ligand-gated channel activity 3/1034 188/18639 0.0159574468085106 0.28765072636734 0.99846755638305 0.999999855387334 GO:0019787 ubiquitin-like protein transferase activity 13/1034 479/18639 0.0271398747390397 0.489226426751412 0.999091933119155 0.999999855387334 GO:0016755 aminoacyltransferase activity 13/1034 496/18639 0.0262096774193548 0.472458585511949 0.999493772427575 0.999999855387334 GO:0099094 ligand-gated monoatomic cation channel activity 1/1034 136/18639 0.00735294117647059 0.132544942541814 0.999586572493916 0.999999855387334 GO:0015276 ligand-gated monoatomic ion channel activity 2/1034 186/18639 0.010752688172043 0.193829163286953 0.999720339876887 0.999999855387334 GO:0045182 translation regulator activity 7/1034 356/18639 0.0196629213483146 0.354446026123052 0.999792182205574 0.999999855387334 GO:0022836 gated channel activity 5/1034 318/18639 0.0157232704402516 0.283429436881866 0.999925715802188 0.999999855387334 GO:0005244 voltage-gated monoatomic ion channel activity 1/1034 173/18639 0.00578034682080925 0.104197180264085 0.999950860470474 0.999999855387334 GO:0022832 voltage-gated channel activity 1/1034 175/18639 0.00571428571428571 0.103006355346781 0.99995620965457 0.999999855387334 GO:0046873 metal ion transmembrane transporter activity 8/1034 450/18639 0.0177777777777778 0.320464216634429 0.999986445561623 0.999999855387334 GO:0030371 translation repressor activity 3/1034 329/18639 0.00911854103343465 0.16437184363848 0.999998739962892 0.999999855387334 GO:0005261 monoatomic cation channel activity 3/1034 341/18639 0.00879765395894428 0.15858749723478 0.99999932775143 0.999999855387334 GO:0005216 monoatomic ion channel activity 5/1034 448/18639 0.0111607142857143 0.201184287786681 0.999999855387334 0.999999855387334