ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 127/1801 175/18639 0.725714285714286 7.51059887364163 6.81367823812081e-90 8.19685492045934e-87 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 42/1801 68/18639 0.617647058823529 6.39218408073946 5.38683624502804e-26 3.24018200138437e-23 GO:0009055 electron transfer activity 52/1801 116/18639 0.448275862068966 4.63931915219514 5.75144103762276e-23 2.30632785608673e-20 GO:0045296 cadherin binding 93/1801 334/18639 0.278443113772455 2.88167751116313 1.25184503843489e-21 3.76492395309295e-19 GO:0022853 active monoatomic ion transmembrane transporter activity 48/1801 118/18639 0.406779661016949 4.20986457617708 3.8694052639455e-19 9.30978906505288e-17 GO:0008137 NADH dehydrogenase (ubiquinone) activity 27/1801 41/18639 0.658536585365854 6.81536003033545 3.03211309590233e-18 6.07938675728418e-16 GO:0003954 NADH dehydrogenase activity 27/1801 44/18639 0.613636363636364 6.35067639190349 4.42392065999061e-17 7.60282364852671e-15 GO:0015399 primary active transmembrane transporter activity 53/1801 166/18639 0.319277108433735 3.30427874741609 1.33360761377078e-15 2.00541244920781e-13 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 29/1801 58/18639 0.5 5.17462520821766 5.51914914154855e-15 7.37726268586989e-13 GO:0051082 unfolded protein binding 41/1801 121/18639 0.338842975206612 3.50677080226321 2.35412494358873e-13 2.83201230713724e-11 GO:0015078 proton transmembrane transporter activity 51/1801 185/18639 0.275675675675676 2.85303660128757 2.77433494116933e-12 3.03411357656973e-10 GO:0016651 oxidoreductase activity, acting on NAD(P)H 32/1801 88/18639 0.363636363636364 3.76336378779466 1.15262140925588e-11 1.15550296277902e-09 GO:0019843 rRNA binding 26/1801 65/18639 0.4 4.13970016657413 8.20507993204121e-11 7.59285473711198e-09 GO:0016860 intramolecular oxidoreductase activity 23/1801 53/18639 0.433962264150943 4.49118414298136 1.40745379232134e-10 1.20940493725898e-08 GO:0044183 protein folding chaperone 27/1801 75/18639 0.36 3.72573014991671 6.01255037877805e-10 4.82206540377999e-08 GO:0004601 peroxidase activity 23/1801 57/18639 0.403508771929825 4.17601332593004 8.18088505659466e-10 6.15100295192711e-08 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 23/1801 59/18639 0.389830508474576 4.0344535521697 1.83561422838785e-09 1.29896700985329e-07 GO:0015035 protein-disulfide reductase activity 17/1801 34/18639 0.5 5.17462520821766 2.43374192788574e-09 1.62655085513697e-07 GO:0003743 translation initiation factor activity 21/1801 51/18639 0.411764705882353 4.26145605382631 2.85822716948943e-09 1.80970909731357e-07 GO:0015036 disulfide oxidoreductase activity 18/1801 40/18639 0.45 4.65716268739589 7.02426962768289e-09 4.22509818105126e-07 GO:0043021 ribonucleoprotein complex binding 43/1801 177/18639 0.242937853107345 2.51422467743909 9.73227975078326e-09 5.57520597152013e-07 GO:0003756 protein disulfide isomerase activity 12/1801 19/18639 0.631578947368421 6.53636868406441 1.68759339700223e-08 8.82684720258122e-07 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 12/1801 19/18639 0.631578947368421 6.53636868406441 1.68759339700223e-08 8.82684720258122e-07 GO:0008135 translation factor activity, RNA binding 26/1801 83/18639 0.313253012048193 3.24193386538938 3.52345918162392e-08 1.76613391478899e-06 GO:0180051 translation factor activity 26/1801 84/18639 0.30952380952381 3.20333941461093 4.63753227631022e-08 2.23158053136048e-06 GO:0016853 isomerase activity 42/1801 180/18639 0.233333333333333 2.41482509716824 4.98553932953617e-08 2.30677069747385e-06 GO:0140662 ATP-dependent protein folding chaperone 17/1801 40/18639 0.425 4.39843142698501 5.25603297503681e-08 2.34185469221084e-06 GO:0048027 mRNA 5'-UTR binding 13/1801 24/18639 0.541666666666667 5.60584397556913 5.51436467697589e-08 2.36920739514357e-06 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 20/1801 54/18639 0.37037037037037 3.83305570979086 5.77715718229097e-08 2.3965241690676e-06 GO:0022804 active transmembrane transporter activity 80/1801 457/18639 0.175054704595186 1.81168497443069 1.07271373267624e-07 4.30158206803172e-06 GO:0004129 cytochrome-c oxidase activity 10/1801 15/18639 0.666666666666667 6.89950027762354 1.31935639572472e-07 5.11995401308659e-06 GO:0031720 haptoglobin binding 8/1801 10/18639 0.8 8.27940033314825 2.8197027110551e-07 1.06003198793728e-05 GO:0016675 oxidoreductase activity, acting on a heme group of donors 10/1801 16/18639 0.625 6.46828151027207 3.21196986636237e-07 1.14586625028366e-05 GO:0016209 antioxidant activity 25/1801 86/18639 0.290697674418605 3.00850302803352 3.23852473064377e-07 1.14586625028366e-05 GO:0055106 ubiquitin-protein transferase regulator activity 15/1801 36/18639 0.416666666666667 4.31218767351471 4.3977438490607e-07 1.51156738583429e-05 GO:1990948 ubiquitin ligase inhibitor activity 8/1801 11/18639 0.727272727272727 7.52672757558932 9.4564734566798e-07 3.1600382134405e-05 GO:0044389 ubiquitin-like protein ligase binding 59/1801 322/18639 0.183229813664596 1.89629122537169 1.08706753655946e-06 3.53443850400279e-05 GO:0031625 ubiquitin protein ligase binding 56/1801 302/18639 0.185430463576159 1.91906630238536 1.37408685899732e-06 4.35006971414152e-05 GO:0055105 ubiquitin-protein transferase inhibitor activity 9/1801 15/18639 0.6 6.20955024986119 2.09890178227089e-06 6.47430472838944e-05 GO:0030515 snoRNA binding 13/1801 32/18639 0.40625 4.20438298167685 3.65663039257689e-06 0.00010997315905675 GO:0043022 ribosome binding 27/1801 112/18639 0.241071428571429 2.49490858253351 6.12361710383018e-06 0.000179675887217261 GO:0051015 actin filament binding 41/1801 209/18639 0.196172248803828 2.03023572762607 8.47606016503609e-06 0.000242778580441391 GO:0005344 oxygen carrier activity 8/1801 14/18639 0.571428571428571 5.91385738082018 1.31779784517298e-05 0.000368676932033278 GO:0003779 actin binding 71/1801 443/18639 0.160270880361174 1.65868347532033 1.38778749385459e-05 0.000379433717069788 GO:0031386 protein tag activity 8/1801 15/18639 0.533333333333333 5.51960022209883 2.58397803596829e-05 0.000675766429841271 GO:0141047 molecular tag activity 8/1801 15/18639 0.533333333333333 5.51960022209883 2.58397803596829e-05 0.000675766429841271 GO:0048029 monosaccharide binding 19/1801 74/18639 0.256756756756757 2.65723997178745 5.61206494662152e-05 0.00143644981506079 GO:0016504 peptidase activator activity 16/1801 57/18639 0.280701754385965 2.90505274847307 6.70913112720078e-05 0.0016814759887547 GO:0004857 enzyme inhibitor activity 64/1801 416/18639 0.153846153846154 1.59219237175928 0.000124090835668178 0.00302180025688771 GO:0003925 G protein activity 15/1801 54/18639 0.277777777777778 2.87479178234314 0.000128106245304466 0.00302180025688771 GO:0015485 cholesterol binding 15/1801 54/18639 0.277777777777778 2.87479178234314 0.000128106245304466 0.00302180025688771 GO:0051087 protein-folding chaperone binding 27/1801 134/18639 0.201492537313433 2.08529672569965 0.000175170524567888 0.00405250271259941 GO:0019003 GDP binding 18/1801 75/18639 0.24 2.48382009994448 0.000220891294181233 0.00501381560188724 GO:0005536 D-glucose binding 6/1801 11/18639 0.545454545454545 5.64504568169199 0.000242942385022934 0.00531381253059254 GO:0034511 U3 snoRNA binding 6/1801 11/18639 0.545454545454545 5.64504568169199 0.000242942385022934 0.00531381253059254 GO:0043236 laminin binding 10/1801 29/18639 0.344827586206897 3.56870704015011 0.000247674584276144 0.00532058080150359 GO:0016829 lyase activity 35/1801 200/18639 0.175 1.81111882287618 0.000391741288323613 0.00826780297988257 GO:0019207 kinase regulator activity 46/1801 287/18639 0.160278745644599 1.6587648751081 0.000426791392579773 0.00885224215988735 GO:0016859 cis-trans isomerase activity 12/1801 42/18639 0.285714285714286 2.95692869041009 0.000448637285523976 0.00914763821161599 GO:0017069 snRNA binding 14/1801 54/18639 0.259259259259259 2.6831389968536 0.000465780437362147 0.00933889776911104 GO:0019838 growth factor binding 26/1801 136/18639 0.191176470588235 1.97853316784793 0.000538881476830129 0.0106274494528958 GO:0001618 virus receptor activity 18/1801 81/18639 0.222222222222222 2.29983342587451 0.000603217814773786 0.0117043714705301 GO:0032977 membrane insertase activity 7/1801 17/18639 0.411764705882353 4.26145605382631 0.00063147139529541 0.0118696888834434 GO:0051787 misfolded protein binding 7/1801 17/18639 0.411764705882353 4.26145605382631 0.00063147139529541 0.0118696888834434 GO:0061133 endopeptidase activator activity 8/1801 22/18639 0.363636363636364 3.76336378779466 0.000692068072521439 0.0128085829422045 GO:0140272 exogenous protein binding 18/1801 82/18639 0.219512195121951 2.27178667677848 0.000704219388187997 0.0128359988483358 GO:0019887 protein kinase regulator activity 41/1801 255/18639 0.16078431372549 1.6639971257798 0.000798194387288616 0.0143317589240031 GO:0098641 cadherin binding involved in cell-cell adhesion 7/1801 18/18639 0.388888888888889 4.0247084952804 0.000947584149561214 0.0167638784106197 GO:0032036 myosin heavy chain binding 6/1801 14/18639 0.428571428571429 4.43539303561513 0.00122313740694819 0.0211241733363738 GO:0002020 protease binding 25/1801 136/18639 0.183823529411765 1.90243573831531 0.00122917051832599 0.0211241733363738 GO:0001094 TFIID-class transcription factor complex binding 5/1801 10/18639 0.5 5.17462520821766 0.00139253735214565 0.023266978258767 GO:0047429 nucleoside triphosphate diphosphatase activity 5/1801 10/18639 0.5 5.17462520821766 0.00139253735214565 0.023266978258767 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 10/1801 36/18639 0.277777777777778 2.87479178234314 0.00167848488301762 0.0269228975236026 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 10/1801 36/18639 0.277777777777778 2.87479178234314 0.00167848488301762 0.0269228975236026 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 10/1801 36/18639 0.277777777777778 2.87479178234314 0.00167848488301762 0.0269228975236026 GO:0032934 sterol binding 15/1801 68/18639 0.220588235294118 2.28292288597838 0.00180655681040026 0.0285958926698884 GO:0098632 cell-cell adhesion mediator activity 13/1801 55/18639 0.236363636363636 2.44618646206653 0.00185207572154035 0.0288850673573057 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 6/1801 15/18639 0.4 4.13970016657413 0.00187284726007468 0.0288850673573057 GO:0043024 ribosomal small subunit binding 7/1801 20/18639 0.35 3.62223764575236 0.00194198186302143 0.0295722048255035 GO:0098631 cell adhesion mediator activity 16/1801 76/18639 0.210526315789474 2.1787895613548 0.00216203748007654 0.0322379344328463 GO:0019210 kinase inhibitor activity 18/1801 90/18639 0.2 2.06985008328706 0.00217063398924402 0.0322379344328463 GO:0010854 adenylate cyclase regulator activity 5/1801 11/18639 0.454545454545455 4.70420473474332 0.00235053315808125 0.0340685709538765 GO:0070990 snRNP binding 5/1801 11/18639 0.454545454545455 4.70420473474332 0.00235053315808125 0.0340685709538765 GO:0022884 macromolecule transmembrane transporter activity 9/1801 32/18639 0.28125 2.91072667962243 0.00258188632946546 0.0369763006469874 GO:0097027 ubiquitin-protein transferase activator activity 6/1801 16/18639 0.375 3.88096890616324 0.00275348249833706 0.0389698758294056 GO:0008320 protein transmembrane transporter activity 8/1801 27/18639 0.296296296296296 3.06644456783269 0.00310167913705259 0.0432262658951105 GO:0140104 molecular carrier activity 38/1801 249/18639 0.152610441767068 1.57940367801021 0.00312608905475861 0.0432262658951105 GO:0005178 integrin binding 27/1801 161/18639 0.167701863354037 1.73558857915375 0.00320113191964949 0.0434330269050566 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 10/1801 39/18639 0.256410256410256 2.65365395293213 0.00321324970453037 0.0434330269050566 GO:0031072 heat shock protein binding 23/1801 131/18639 0.175572519083969 1.81704396624437 0.00346925393668804 0.0461630611965267 GO:0061134 peptidase regulator activity 35/1801 226/18639 0.154867256637168 1.60276002024441 0.0034919688851903 0.0461630611965267 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 5/1801 12/18639 0.416666666666667 4.31218767351471 0.00371081138333807 0.0485228923277793 GO:0051537 2 iron, 2 sulfur cluster binding 8/1801 28/18639 0.285714285714286 2.95692869041009 0.00398001872554793 0.0514834680304748 GO:0019825 oxygen binding 9/1801 34/18639 0.264705882352941 2.73950746317405 0.00404777230003007 0.0518028731588955 GO:0050840 extracellular matrix binding 14/1801 67/18639 0.208955223880597 2.1625299377626 0.00427801616376185 0.0541731941579527 GO:0003924 GTPase activity 47/1801 331/18639 0.141993957703928 1.46953102589867 0.00472576926236517 0.0576599658198761 GO:0140318 protein transporter activity 10/1801 41/18639 0.24390243902439 2.52420741864276 0.00474388878264619 0.0576599658198761 GO:0004602 glutathione peroxidase activity 7/1801 23/18639 0.304347826086957 3.14977186587162 0.00474508446896736 0.0576599658198761 GO:0017134 fibroblast growth factor binding 7/1801 23/18639 0.304347826086957 3.14977186587162 0.00474508446896736 0.0576599658198761 GO:0003713 transcription coactivator activity 38/1801 256/18639 0.1484375 1.53621685868962 0.0050205020478444 0.0603222938412303 GO:0005200 structural constituent of cytoskeleton 20/1801 112/18639 0.178571428571429 1.84808043150631 0.00506446523521551 0.0603222938412303 GO:0070628 proteasome binding 6/1801 18/18639 0.333333333333333 3.44975013881177 0.00539262257521358 0.0636012250782543 GO:0019855 calcium channel inhibitor activity 5/1801 13/18639 0.384615384615385 3.9804809293982 0.00555449336186097 0.0648743253817354 GO:0004860 protein kinase inhibitor activity 16/1801 84/18639 0.19047619047619 1.97128579360673 0.00611819354789832 0.0697853130365719 GO:0051117 ATPase binding 16/1801 84/18639 0.19047619047619 1.97128579360673 0.00611819354789832 0.0697853130365719 GO:0050699 WW domain binding 7/1801 24/18639 0.291666666666667 3.0185313714603 0.0061489968261651 0.0697853130365719 GO:0001968 fibronectin binding 8/1801 30/18639 0.266666666666667 2.75980011104942 0.00629892891784242 0.0702467396036844 GO:0051540 metal cluster binding 15/1801 77/18639 0.194805194805195 2.01608774346142 0.00630644046317366 0.0702467396036844 GO:0008301 DNA binding, bending 6/1801 19/18639 0.315789473684211 3.2681843420322 0.00724641584955711 0.0799127281162604 GO:0019001 guanyl nucleotide binding 54/1801 400/18639 0.135 1.39714880621877 0.00737349361671231 0.0799127281162604 GO:0032561 guanyl ribonucleotide binding 54/1801 400/18639 0.135 1.39714880621877 0.00737349361671231 0.0799127281162604 GO:0044548 S100 protein binding 5/1801 14/18639 0.357142857142857 3.69616086301261 0.00796080222570143 0.0855075453349895 GO:0043531 ADP binding 9/1801 38/18639 0.236842105263158 2.45113825652415 0.00885523345934856 0.0942729721380206 GO:0005525 GTP binding 51/1801 378/18639 0.134920634920635 1.3963274371381 0.00911383567391962 0.0961749501379412 GO:0043539 protein serine/threonine kinase activator activity 14/1801 73/18639 0.191780821917808 1.98478775109718 0.00937559768072829 0.0978825032069939 GO:0031369 translation initiation factor binding 8/1801 32/18639 0.25 2.58731260410883 0.00951908289922163 0.0978825032069939 GO:0000339 RNA cap binding 6/1801 20/18639 0.3 3.10477512493059 0.00951974470092958 0.0978825032069939 GO:0005080 protein kinase C binding 11/1801 52/18639 0.211538461538462 2.18926451116901 0.00975382847301782 0.0994394546867833 GO:0070006 metalloaminopeptidase activity 7/1801 26/18639 0.269230769230769 2.78633665057874 0.00985160953098928 0.0995923215611774 GO:0000774 adenyl-nucleotide exchange factor activity 5/1801 15/18639 0.333333333333333 3.44975013881177 0.0110047797085148 0.110322916577861 GO:0005522 profilin binding 4/1801 10/18639 0.4 4.13970016657413 0.0113238138511853 0.110752423276227 GO:0005528 FK506 binding 4/1801 10/18639 0.4 4.13970016657413 0.0113238138511853 0.110752423276227 GO:0050815 phosphoserine residue binding 4/1801 10/18639 0.4 4.13970016657413 0.0113238138511853 0.110752423276227 GO:0003697 single-stranded DNA binding 20/1801 121/18639 0.165289256198347 1.71061990354303 0.0119168513360073 0.115612678687232 GO:0004177 aminopeptidase activity 9/1801 40/18639 0.225 2.32858134369795 0.0124720679484831 0.120031181936201 GO:0051536 iron-sulfur cluster binding 14/1801 76/18639 0.184210526315789 1.90644086618545 0.0132873120230126 0.126862193362573 GO:0043178 alcohol binding 16/1801 92/18639 0.173913043478261 1.79986963764092 0.0145524865649806 0.136543917903493 GO:0061650 ubiquitin-like protein conjugating enzyme activity 9/1801 41/18639 0.219512195121951 2.27178667677848 0.0146456183388747 0.136543917903493 GO:0017070 U6 snRNA binding 5/1801 16/18639 0.3125 3.23414075513604 0.0147553693495047 0.136543917903493 GO:0140327 flippase activity 5/1801 16/18639 0.3125 3.23414075513604 0.0147553693495047 0.136543917903493 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 10/1801 48/18639 0.208333333333333 2.15609383675736 0.0149128329828935 0.136947618919244 GO:0070034 telomerase RNA binding 6/1801 22/18639 0.272727272727273 2.82252284084599 0.0155068369579361 0.141323673184827 GO:0016887 ATP hydrolysis activity 54/1801 417/18639 0.129496402877698 1.34019070140889 0.01611930064024 0.144460128400467 GO:0005225 volume-sensitive anion channel activity 4/1801 11/18639 0.363636363636364 3.76336378779466 0.0164514028186733 0.144460128400467 GO:0015217 ADP transmembrane transporter activity 4/1801 11/18639 0.363636363636364 3.76336378779466 0.0164514028186733 0.144460128400467 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 4/1801 11/18639 0.363636363636364 3.76336378779466 0.0164514028186733 0.144460128400467 GO:0034713 type I transforming growth factor beta receptor binding 4/1801 11/18639 0.363636363636364 3.76336378779466 0.0164514028186733 0.144460128400467 GO:0019208 phosphatase regulator activity 19/1801 117/18639 0.162393162393162 1.68064750352368 0.016707792822395 0.145648367864791 GO:0008307 structural constituent of muscle 9/1801 42/18639 0.214285714285714 2.21769651780757 0.01708588757978 0.147872825600542 GO:0016835 carbon-oxygen lyase activity 14/1801 79/18639 0.177215189873418 1.83404437759613 0.0183545511817141 0.157718036225729 GO:0004029 aldehyde dehydrogenase (NAD+) activity 5/1801 17/18639 0.294117647058824 3.0438971813045 0.0192738802867999 0.163285056232537 GO:0004550 nucleoside diphosphate kinase activity 5/1801 17/18639 0.294117647058824 3.0438971813045 0.0192738802867999 0.163285056232537 GO:0044325 transmembrane transporter binding 21/1801 136/18639 0.154411764705882 1.59804602018486 0.0209534565614996 0.176272784919469 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 20/1801 128/18639 0.15625 1.61707037756802 0.021207604354336 0.177171861376848 GO:0005527 macrolide binding 4/1801 12/18639 0.333333333333333 3.44975013881177 0.022821698536341 0.185503400940664 GO:0008179 adenylate cyclase binding 4/1801 12/18639 0.333333333333333 3.44975013881177 0.022821698536341 0.185503400940664 GO:0010853 cyclase activator activity 4/1801 12/18639 0.333333333333333 3.44975013881177 0.022821698536341 0.185503400940664 GO:0017166 vinculin binding 4/1801 12/18639 0.333333333333333 3.44975013881177 0.022821698536341 0.185503400940664 GO:0001091 RNA polymerase II general transcription initiation factor binding 6/1801 24/18639 0.25 2.58731260410883 0.0236904711143157 0.189997578336812 GO:0005540 hyaluronic acid binding 6/1801 24/18639 0.25 2.58731260410883 0.0236904711143157 0.189997578336812 GO:0045309 protein phosphorylated amino acid binding 11/1801 59/18639 0.186440677966102 1.92952126408116 0.02431117267778 0.192267721748479 GO:0016758 hexosyltransferase activity 28/1801 197/18639 0.142131979695431 1.47095945005172 0.0245257813140195 0.192267721748479 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 5/1801 18/18639 0.277777777777778 2.87479178234314 0.0246128255604869 0.192267721748479 GO:1990381 ubiquitin-specific protease binding 5/1801 18/18639 0.277777777777778 2.87479178234314 0.0246128255604869 0.192267721748479 GO:0008378 galactosyltransferase activity 7/1801 32/18639 0.21875 2.26389852859522 0.0303247949391557 0.227966730129992 GO:0120015 sterol transfer activity 7/1801 32/18639 0.21875 2.26389852859522 0.0303247949391557 0.227966730129992 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 11/1801 61/18639 0.180327868852459 1.8662582718162 0.0304530140998642 0.227966730129992 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 4/1801 13/18639 0.307692307692308 3.18438474351856 0.030496011947221 0.227966730129992 GO:0005172 vascular endothelial growth factor receptor binding 4/1801 13/18639 0.307692307692308 3.18438474351856 0.030496011947221 0.227966730129992 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 4/1801 13/18639 0.307692307692308 3.18438474351856 0.030496011947221 0.227966730129992 GO:0016776 phosphotransferase activity, phosphate group as acceptor 8/1801 39/18639 0.205128205128205 2.12292316234571 0.0305092631346041 0.227966730129992 GO:0061135 endopeptidase regulator activity 26/1801 184/18639 0.141304347826087 1.46239408058325 0.0313212574867349 0.232589338003346 GO:0020037 heme binding 21/1801 142/18639 0.147887323943662 1.53052294890945 0.0321299982033085 0.23713121373362 GO:0050750 low-density lipoprotein particle receptor binding 6/1801 26/18639 0.230769230769231 2.38828855763892 0.0343489683320033 0.251962249410976 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 8/1801 40/18639 0.2 2.06985008328706 0.0350185619311344 0.252259461096735 GO:0061791 GTPase motor activity 8/1801 40/18639 0.2 2.06985008328706 0.0350185619311344 0.252259461096735 GO:1990606 membrane scission GTPase motor activity 8/1801 40/18639 0.2 2.06985008328706 0.0350185619311344 0.252259461096735 GO:0005507 copper ion binding 11/1801 63/18639 0.174603174603175 1.80701197747283 0.037627465065901 0.265540530119097 GO:0010851 cyclase regulator activity 5/1801 20/18639 0.25 2.58731260410883 0.0379135714236393 0.265540530119097 GO:0030742 GTP-dependent protein binding 5/1801 20/18639 0.25 2.58731260410883 0.0379135714236393 0.265540530119097 GO:0042288 MHC class I protein binding 5/1801 20/18639 0.25 2.58731260410883 0.0379135714236393 0.265540530119097 GO:0003774 cytoskeletal motor activity 22/1801 153/18639 0.143790849673203 1.48812751085998 0.0379658945806191 0.265540530119097 GO:0016757 glycosyltransferase activity 35/1801 267/18639 0.131086142322097 1.35664331301587 0.0390100462983513 0.271266391311656 GO:0005347 ATP transmembrane transporter activity 4/1801 14/18639 0.285714285714286 2.95692869041009 0.0395100958358288 0.271603687374298 GO:0016530 metallochaperone activity 4/1801 14/18639 0.285714285714286 2.95692869041009 0.0395100958358288 0.271603687374298 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 8/1801 41/18639 0.195121951219512 2.01936593491421 0.0399574573474398 0.271832691439925 GO:0019212 phosphatase inhibitor activity 10/1801 56/18639 0.178571428571429 1.84808043150631 0.0403400885805 0.271832691439925 GO:0004364 glutathione transferase activity 6/1801 27/18639 0.222222222222222 2.29983342587451 0.0406732206643279 0.271832691439925 GO:0005385 zinc ion transmembrane transporter activity 6/1801 27/18639 0.222222222222222 2.29983342587451 0.0406732206643279 0.271832691439925 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 6/1801 27/18639 0.222222222222222 2.29983342587451 0.0406732206643279 0.271832691439925 GO:0140297 DNA-binding transcription factor binding 59/1801 488/18639 0.120901639344262 1.25124134133132 0.0422717874697581 0.27954312529271 GO:0005518 collagen binding 12/1801 72/18639 0.166666666666667 1.72487506940589 0.0422916448905015 0.27954312529271 GO:0060590 ATPase regulator activity 9/1801 49/18639 0.183673469387755 1.90088272954934 0.0429730084006147 0.282494694567975 GO:0019200 carbohydrate kinase activity 5/1801 21/18639 0.238095238095238 2.46410724200841 0.0459307404941477 0.298673950348431 GO:1904047 S-adenosyl-L-methionine binding 5/1801 21/18639 0.238095238095238 2.46410724200841 0.0459307404941477 0.298673950348431 GO:0005154 epidermal growth factor receptor binding 7/1801 35/18639 0.2 2.06985008328706 0.04710907544518 0.304046469002853 GO:0019209 kinase activator activity 21/1801 148/18639 0.141891891891892 1.46847472125096 0.0472624187061792 0.304046469002853 GO:0046875 ephrin receptor binding 6/1801 28/18639 0.214285714285714 2.21769651780757 0.0476862515773338 0.305141280040067 GO:0016846 carbon-sulfur lyase activity 4/1801 15/18639 0.266666666666667 2.75980011104942 0.0498756653366703 0.314138352879656 GO:0048531 beta-1,3-galactosyltransferase activity 4/1801 15/18639 0.266666666666667 2.75980011104942 0.0498756653366703 0.314138352879656 GO:0050780 dopamine receptor binding 4/1801 15/18639 0.266666666666667 2.75980011104942 0.0498756653366703 0.314138352879656 GO:0008200 ion channel inhibitor activity 8/1801 43/18639 0.186046511627907 1.92544193794145 0.0511742344116731 0.32063856248564 GO:0019888 protein phosphatase regulator activity 16/1801 107/18639 0.149532710280374 1.54755146413986 0.0515582722275674 0.321370992174941 GO:0005048 signal sequence binding 9/1801 51/18639 0.176470588235294 1.8263383087827 0.0536005548425072 0.332378698327506 GO:0140035 ubiquitin-like protein reader activity 5/1801 22/18639 0.227272727272727 2.35210236737166 0.0548789474165628 0.333233507238455 GO:0140517 protein-RNA adaptor activity 5/1801 22/18639 0.227272727272727 2.35210236737166 0.0548789474165628 0.333233507238455 GO:0005201 extracellular matrix structural constituent 23/1801 168/18639 0.136904761904762 1.41686166415483 0.0552841945764143 0.333233507238455 GO:0005496 steroid binding 16/1801 108/18639 0.148148148148148 1.53322228391634 0.0553289478347615 0.333233507238455 GO:0003785 actin monomer binding 6/1801 29/18639 0.206896551724138 2.14122422409006 0.0554004168309984 0.333233507238455 GO:0035250 UDP-galactosyltransferase activity 6/1801 29/18639 0.206896551724138 2.14122422409006 0.0554004168309984 0.333233507238455 GO:0016248 channel inhibitor activity 8/1801 44/18639 0.181818181818182 1.88168189389733 0.0574720699529369 0.34227178293754 GO:0019205 nucleobase-containing compound kinase activity 8/1801 44/18639 0.181818181818182 1.88168189389733 0.0574720699529369 0.34227178293754 GO:0046906 tetrapyrrole binding 21/1801 152/18639 0.138157894736842 1.42983064963909 0.0598506338258521 0.354681342327587 GO:0004714 transmembrane receptor protein tyrosine kinase activity 10/1801 60/18639 0.166666666666667 1.72487506940589 0.0604037605582215 0.356171461975326 GO:0005159 insulin-like growth factor receptor binding 4/1801 16/18639 0.25 2.58731260410883 0.0615824306657255 0.356171461975326 GO:0008142 oxysterol binding 4/1801 16/18639 0.25 2.58731260410883 0.0615824306657255 0.356171461975326 GO:0030275 LRR domain binding 4/1801 16/18639 0.25 2.58731260410883 0.0615824306657255 0.356171461975326 GO:0140328 floppase activity 4/1801 16/18639 0.25 2.58731260410883 0.0615824306657255 0.356171461975326 GO:0051219 phosphoprotein binding 14/1801 93/18639 0.150537634408602 1.55795167559241 0.0625909296781252 0.360272193314759 GO:0016769 transferase activity, transferring nitrogenous groups 6/1801 30/18639 0.2 2.06985008328706 0.0638226292917516 0.360623257966884 GO:0141110 transporter inhibitor activity 8/1801 45/18639 0.177777777777778 1.83986674069961 0.0642392396245717 0.360623257966884 GO:0004090 carbonyl reductase (NADPH) activity 3/1801 10/18639 0.3 3.10477512493059 0.0644505407006485 0.360623257966884 GO:0008190 eukaryotic initiation factor 4E binding 3/1801 10/18639 0.3 3.10477512493059 0.0644505407006485 0.360623257966884 GO:0031996 thioesterase binding 3/1801 10/18639 0.3 3.10477512493059 0.0644505407006485 0.360623257966884 GO:1990757 ubiquitin ligase activator activity 3/1801 10/18639 0.3 3.10477512493059 0.0644505407006485 0.360623257966884 GO:0140103 catalytic activity, acting on a glycoprotein 5/1801 23/18639 0.217391304347826 2.24983704705116 0.064760570992753 0.360680402334638 GO:0140296 general transcription initiation factor binding 9/1801 53/18639 0.169811320754717 1.75741988203619 0.0658062303230639 0.364815184694221 GO:0030246 carbohydrate binding 35/1801 280/18639 0.125 1.29365630205441 0.0684057075546359 0.376592691453326 GO:0000146 microfilament motor activity 7/1801 38/18639 0.184210526315789 1.90644086618545 0.0688698188858951 0.376592691453326 GO:0042162 telomeric DNA binding 7/1801 38/18639 0.184210526315789 1.90644086618545 0.0688698188858951 0.376592691453326 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 8/1801 46/18639 0.173913043478261 1.79986963764092 0.0714802352971869 0.389098294400524 GO:0051287 NAD binding 9/1801 54/18639 0.166666666666667 1.72487506940589 0.0725141830017902 0.392948478158349 GO:0070325 lipoprotein particle receptor binding 6/1801 31/18639 0.193548387096774 2.00308072576167 0.0729544094184711 0.39356123107812 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 4/1801 17/18639 0.235294117647059 2.4351177450436 0.0746004461669335 0.397098835127526 GO:0016018 cyclosporin A binding 4/1801 17/18639 0.235294117647059 2.4351177450436 0.0746004461669335 0.397098835127526 GO:0048038 quinone binding 4/1801 17/18639 0.235294117647059 2.4351177450436 0.0746004461669335 0.397098835127526 GO:0050431 transforming growth factor beta binding 5/1801 24/18639 0.208333333333333 2.15609383675736 0.0755684920133944 0.397631979847146 GO:0070300 phosphatidic acid binding 5/1801 24/18639 0.208333333333333 2.15609383675736 0.0755684920133944 0.397631979847146 GO:0016798 hydrolase activity, acting on glycosyl bonds 18/1801 130/18639 0.138461538461538 1.43297313458335 0.0756922056400635 0.397631979847146 GO:0030295 protein kinase activator activity 19/1801 139/18639 0.136690647482014 1.41464574037605 0.0769214295291419 0.402332520537207 GO:0000217 DNA secondary structure binding 7/1801 39/18639 0.179487179487179 1.85755776705249 0.07726119045649 0.402360225624058 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 17/1801 122/18639 0.139344262295082 1.44210866458525 0.0787888217948962 0.408547209565776 GO:0000049 tRNA binding 12/1801 80/18639 0.15 1.5523875624653 0.0822139037693383 0.414994963958756 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 3/1801 11/18639 0.272727272727273 2.82252284084599 0.0824502174063889 0.414994963958756 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 3/1801 11/18639 0.272727272727273 2.82252284084599 0.0824502174063889 0.414994963958756 GO:0032794 GTPase activating protein binding 3/1801 11/18639 0.272727272727273 2.82252284084599 0.0824502174063889 0.414994963958756 GO:0048407 platelet-derived growth factor binding 3/1801 11/18639 0.272727272727273 2.82252284084599 0.0824502174063889 0.414994963958756 GO:0050786 RAGE receptor binding 3/1801 11/18639 0.272727272727273 2.82252284084599 0.0824502174063889 0.414994963958756 GO:0050998 nitric-oxide synthase binding 3/1801 11/18639 0.272727272727273 2.82252284084599 0.0824502174063889 0.414994963958756 GO:0051059 NF-kappaB binding 6/1801 32/18639 0.1875 1.94048445308162 0.0827920127598516 0.414994963958756 GO:0042277 peptide binding 31/1801 249/18639 0.124497991967871 1.28846089521885 0.0855729888805734 0.427154795117551 GO:0004532 RNA exonuclease activity 7/1801 40/18639 0.175 1.81111882287618 0.0862217480224744 0.428614722607589 GO:0030170 pyridoxal phosphate binding 9/1801 56/18639 0.160714285714286 1.66327238835568 0.0871529533175633 0.430351961314316 GO:0120020 cholesterol transfer activity 5/1801 25/18639 0.2 2.06985008328706 0.0872866820953392 0.430351961314316 GO:0003746 translation elongation factor activity 4/1801 18/18639 0.222222222222222 2.29983342587451 0.088882623483061 0.436431820612744 GO:0070279 vitamin B6 binding 9/1801 57/18639 0.157894736842105 1.6340921710161 0.0950839400910932 0.464983658250346 GO:0001530 lipopolysaccharide binding 7/1801 41/18639 0.170731707317073 1.76694519304993 0.0957467490438052 0.465804331909531 GO:1990782 protein tyrosine kinase binding 16/1801 117/18639 0.136752136752137 1.41528210823047 0.0979516670603428 0.465804331909531 GO:0003684 damaged DNA binding 11/1801 74/18639 0.148648648648649 1.53840208892957 0.0980895931408294 0.465804331909531 GO:0005516 calmodulin binding 26/1801 207/18639 0.1256038647343 1.29990584940733 0.0997058306096596 0.465804331909531 GO:0005160 transforming growth factor beta receptor binding 5/1801 26/18639 0.192307692307692 1.9902404646991 0.0998908996580381 0.465804331909531 GO:0000340 RNA 7-methylguanosine cap binding 3/1801 12/18639 0.25 2.58731260410883 0.102326390363072 0.465804331909531 GO:0004526 ribonuclease P activity 3/1801 12/18639 0.25 2.58731260410883 0.102326390363072 0.465804331909531 GO:0005049 nuclear export signal receptor activity 3/1801 12/18639 0.25 2.58731260410883 0.102326390363072 0.465804331909531 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 3/1801 12/18639 0.25 2.58731260410883 0.102326390363072 0.465804331909531 GO:0015368 calcium:monoatomic cation antiporter activity 3/1801 12/18639 0.25 2.58731260410883 0.102326390363072 0.465804331909531 GO:0016208 AMP binding 3/1801 12/18639 0.25 2.58731260410883 0.102326390363072 0.465804331909531 GO:0016840 carbon-nitrogen lyase activity 3/1801 12/18639 0.25 2.58731260410883 0.102326390363072 0.465804331909531 GO:0031543 peptidyl-proline dioxygenase activity 3/1801 12/18639 0.25 2.58731260410883 0.102326390363072 0.465804331909531 GO:0035251 UDP-glucosyltransferase activity 3/1801 12/18639 0.25 2.58731260410883 0.102326390363072 0.465804331909531 GO:0035259 nuclear glucocorticoid receptor binding 3/1801 12/18639 0.25 2.58731260410883 0.102326390363072 0.465804331909531 GO:0097371 MDM2/MDM4 family protein binding 3/1801 12/18639 0.25 2.58731260410883 0.102326390363072 0.465804331909531 GO:0005346 purine ribonucleotide transmembrane transporter activity 4/1801 19/18639 0.210526315789474 2.1787895613548 0.104367292480421 0.465804331909531 GO:0030506 ankyrin binding 4/1801 19/18639 0.210526315789474 2.1787895613548 0.104367292480421 0.465804331909531 GO:0034987 immunoglobulin receptor binding 4/1801 19/18639 0.210526315789474 2.1787895613548 0.104367292480421 0.465804331909531 GO:0046624 sphingolipid transporter activity 4/1801 19/18639 0.210526315789474 2.1787895613548 0.104367292480421 0.465804331909531 GO:0050145 nucleoside monophosphate kinase activity 4/1801 19/18639 0.210526315789474 2.1787895613548 0.104367292480421 0.465804331909531 GO:0097001 ceramide binding 4/1801 19/18639 0.210526315789474 2.1787895613548 0.104367292480421 0.465804331909531 GO:0016831 carboxy-lyase activity 6/1801 34/18639 0.176470588235294 1.8263383087827 0.104544613146777 0.465804331909531 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 6/1801 34/18639 0.176470588235294 1.8263383087827 0.104544613146777 0.465804331909531 GO:0003725 double-stranded RNA binding 11/1801 75/18639 0.146666666666667 1.51789006107718 0.105456937246757 0.466342281156418 GO:0031492 nucleosomal DNA binding 7/1801 42/18639 0.166666666666667 1.72487506940589 0.105828298217541 0.466342281156418 GO:0051879 Hsp90 protein binding 7/1801 42/18639 0.166666666666667 1.72487506940589 0.105828298217541 0.466342281156418 GO:0016922 nuclear receptor binding 18/1801 137/18639 0.131386861313869 1.35975552916668 0.110922938024669 0.48700837388203 GO:0017022 myosin binding 11/1801 76/18639 0.144736842105263 1.49791782343143 0.113138046467633 0.494927526911138 GO:0016830 carbon-carbon lyase activity 8/1801 51/18639 0.156862745098039 1.62341183002907 0.114791817700797 0.496794110570773 GO:0030544 Hsp70 protein binding 8/1801 51/18639 0.156862745098039 1.62341183002907 0.114791817700797 0.496794110570773 GO:0035591 signaling adaptor activity 17/1801 129/18639 0.131782945736434 1.36385470604186 0.116354826294972 0.496794110570773 GO:0000175 3'-5'-RNA exonuclease activity 6/1801 35/18639 0.171428571428571 1.77415721424605 0.11642782784366 0.496794110570773 GO:0061631 ubiquitin conjugating enzyme activity 6/1801 35/18639 0.171428571428571 1.77415721424605 0.11642782784366 0.496794110570773 GO:0008375 acetylglucosaminyltransferase activity 7/1801 43/18639 0.162790697674419 1.68476169569877 0.116455477290904 0.496794110570773 GO:0048156 tau protein binding 7/1801 43/18639 0.162790697674419 1.68476169569877 0.116455477290904 0.496794110570773 GO:0052745 inositol phosphate phosphatase activity 4/1801 20/18639 0.2 2.06985008328706 0.120980722744616 0.513869762679503 GO:0008035 high-density lipoprotein particle binding 3/1801 13/18639 0.230769230769231 2.38828855763892 0.123875503887827 0.513869762679503 GO:0019104 DNA N-glycosylase activity 3/1801 13/18639 0.230769230769231 2.38828855763892 0.123875503887827 0.513869762679503 GO:0031432 titin binding 3/1801 13/18639 0.230769230769231 2.38828855763892 0.123875503887827 0.513869762679503 GO:0043560 insulin receptor substrate binding 3/1801 13/18639 0.230769230769231 2.38828855763892 0.123875503887827 0.513869762679503 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 3/1801 13/18639 0.230769230769231 2.38828855763892 0.123875503887827 0.513869762679503 GO:0140333 glycerophospholipid flippase activity 3/1801 13/18639 0.230769230769231 2.38828855763892 0.123875503887827 0.513869762679503 GO:0140410 monoatomic cation:bicarbonate symporter activity 3/1801 13/18639 0.230769230769231 2.38828855763892 0.123875503887827 0.513869762679503 GO:0030020 extracellular matrix structural constituent conferring tensile strength 7/1801 44/18639 0.159090909090909 1.64647165716016 0.12761450030079 0.523999185438101 GO:0046625 sphingolipid binding 5/1801 28/18639 0.178571428571429 1.84808043150631 0.127624074258822 0.523999185438101 GO:0097718 disordered domain specific binding 5/1801 28/18639 0.178571428571429 1.84808043150631 0.127624074258822 0.523999185438101 GO:0019199 transmembrane receptor protein kinase activity 11/1801 78/18639 0.141025641025641 1.45950967411267 0.12942918216709 0.529603082132686 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 17/1801 132/18639 0.128787878787879 1.33285800817728 0.135264255369837 0.546355680528005 GO:0004864 protein phosphatase inhibitor activity 8/1801 53/18639 0.150943396226415 1.56215100625439 0.135339977387652 0.546355680528005 GO:0005003 ephrin receptor activity 8/1801 53/18639 0.150943396226415 1.56215100625439 0.135339977387652 0.546355680528005 GO:0005005 transmembrane-ephrin receptor activity 8/1801 53/18639 0.150943396226415 1.56215100625439 0.135339977387652 0.546355680528005 GO:0005319 lipid transporter activity 22/1801 178/18639 0.123595505617978 1.27912083798639 0.137430396251191 0.551199128887184 GO:0046332 SMAD binding 11/1801 79/18639 0.139240506329114 1.44103486811125 0.138030707359774 0.551199128887184 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 4/1801 21/18639 0.19047619047619 1.97128579360673 0.138639542097668 0.551199128887184 GO:0072542 protein phosphatase activator activity 4/1801 21/18639 0.19047619047619 1.97128579360673 0.138639542097668 0.551199128887184 GO:0046915 transition metal ion transmembrane transporter activity 7/1801 45/18639 0.155555555555556 1.60988339811216 0.139288890425357 0.551199128887184 GO:0140303 intramembrane lipid transporter activity 7/1801 45/18639 0.155555555555556 1.60988339811216 0.139288890425357 0.551199128887184 GO:0004197 cysteine-type endopeptidase activity 12/1801 88/18639 0.136363636363636 1.411261420423 0.140055932334827 0.55241733311081 GO:0022829 wide pore channel activity 6/1801 37/18639 0.162162162162162 1.67825682428681 0.142096807343721 0.558635487694433 GO:0051861 glycolipid binding 5/1801 29/18639 0.172413793103448 1.78435352007505 0.142670669556286 0.55906454552512 GO:0008191 metalloendopeptidase inhibitor activity 3/1801 14/18639 0.214285714285714 2.21769651780757 0.146884251538372 0.56834608731651 GO:0098847 sequence-specific single stranded DNA binding 3/1801 14/18639 0.214285714285714 2.21769651780757 0.146884251538372 0.56834608731651 GO:1990825 sequence-specific mRNA binding 3/1801 14/18639 0.214285714285714 2.21769651780757 0.146884251538372 0.56834608731651 GO:0048306 calcium-dependent protein binding 11/1801 80/18639 0.1375 1.42302193225986 0.146929038366945 0.56834608731651 GO:0003727 single-stranded RNA binding 12/1801 89/18639 0.134831460674157 1.3954045505306 0.148528379172769 0.57269115431039 GO:0019955 cytokine binding 18/1801 144/18639 0.125 1.29365630205441 0.154719508037075 0.594656767311823 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 6/1801 38/18639 0.157894736842105 1.6340921710161 0.155826867679564 0.595636418637059 GO:0030971 receptor tyrosine kinase binding 11/1801 81/18639 0.135802469135802 1.40545376025665 0.156117717723699 0.595636418637059 GO:0030021 extracellular matrix structural constituent conferring compression resistance 4/1801 22/18639 0.181818181818182 1.88168189389733 0.157253007582357 0.595636418637059 GO:0031683 G-protein beta/gamma-subunit complex binding 4/1801 22/18639 0.181818181818182 1.88168189389733 0.157253007582357 0.595636418637059 GO:0140313 molecular sequestering activity 8/1801 55/18639 0.145454545454545 1.50534551511786 0.157608627230003 0.595636418637059 GO:0008106 alcohol dehydrogenase (NADP+) activity 5/1801 30/18639 0.166666666666667 1.72487506940589 0.158440277609193 0.595636418637059 GO:0015215 nucleotide transmembrane transporter activity 5/1801 30/18639 0.166666666666667 1.72487506940589 0.158440277609193 0.595636418637059 GO:0008194 UDP-glycosyltransferase activity 18/1801 145/18639 0.124137931034483 1.28473453445404 0.161656115101223 0.605832730426079 GO:0005504 fatty acid binding 7/1801 47/18639 0.148936170212766 1.54137772159675 0.164105592787076 0.613102571810101 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 6/1801 39/18639 0.153846153846154 1.59219237175928 0.170111536265577 0.623869960305525 GO:0004559 alpha-mannosidase activity 3/1801 15/18639 0.2 2.06985008328706 0.171136398088797 0.623869960305525 GO:0005041 low-density lipoprotein particle receptor activity 3/1801 15/18639 0.2 2.06985008328706 0.171136398088797 0.623869960305525 GO:0015929 hexosaminidase activity 3/1801 15/18639 0.2 2.06985008328706 0.171136398088797 0.623869960305525 GO:0033130 acetylcholine receptor binding 3/1801 15/18639 0.2 2.06985008328706 0.171136398088797 0.623869960305525 GO:0034483 heparan sulfate sulfotransferase activity 3/1801 15/18639 0.2 2.06985008328706 0.171136398088797 0.623869960305525 GO:0061578 K63-linked deubiquitinase activity 3/1801 15/18639 0.2 2.06985008328706 0.171136398088797 0.623869960305525 GO:0120283 protein serine/threonine kinase binding 3/1801 15/18639 0.2 2.06985008328706 0.171136398088797 0.623869960305525 GO:0031491 nucleosome binding 10/1801 74/18639 0.135135135135135 1.39854735357234 0.174457400693341 0.634055145118095 GO:0000295 adenine nucleotide transmembrane transporter activity 4/1801 23/18639 0.173913043478261 1.79986963764092 0.176725099495958 0.636898147467914 GO:0005158 insulin receptor binding 4/1801 23/18639 0.173913043478261 1.79986963764092 0.176725099495958 0.636898147467914 GO:0015631 tubulin binding 43/1801 385/18639 0.111688311688312 1.15589030625122 0.176827914592089 0.636898147467914 GO:0008238 exopeptidase activity 13/1801 102/18639 0.127450980392157 1.31902211189862 0.184134565767022 0.658146410361411 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 6/1801 40/18639 0.15 1.5523875624653 0.184915616543771 0.658146410361411 GO:0050997 quaternary ammonium group binding 6/1801 40/18639 0.15 1.5523875624653 0.184915616543771 0.658146410361411 GO:0071949 FAD binding 6/1801 40/18639 0.15 1.5523875624653 0.184915616543771 0.658146410361411 GO:0003712 transcription coregulator activity 54/1801 495/18639 0.109090909090909 1.1290091363384 0.189632058556426 0.672942083903778 GO:0140142 nucleocytoplasmic carrier activity 5/1801 32/18639 0.15625 1.61707037756802 0.191933174106244 0.679104730734739 GO:0004713 protein tyrosine kinase activity 17/1801 140/18639 0.121428571428571 1.25669469342429 0.193562814701592 0.680496513693934 GO:0008408 3'-5' exonuclease activity 8/1801 58/18639 0.137931034482759 1.42748281606004 0.19396554451185 0.680496513693934 GO:0008234 cysteine-type peptidase activity 22/1801 187/18639 0.117647058823529 1.2175588725218 0.194023528010822 0.680496513693934 GO:0015923 mannosidase activity 3/1801 16/18639 0.1875 1.94048445308162 0.196418082878737 0.684901315081508 GO:0043023 ribosomal large subunit binding 3/1801 16/18639 0.1875 1.94048445308162 0.196418082878737 0.684901315081508 GO:0005543 phospholipid binding 54/1801 497/18639 0.108651911468813 1.1244658400151 0.197999023944345 0.688418571690886 GO:0042169 SH2 domain binding 6/1801 41/18639 0.146341463414634 1.51452445118566 0.200201708115195 0.692076594432699 GO:0042287 MHC protein binding 6/1801 41/18639 0.146341463414634 1.51452445118566 0.200201708115195 0.692076594432699 GO:0035091 phosphatidylinositol binding 32/1801 284/18639 0.112676056338028 1.16611272297863 0.203171144960507 0.700329190222034 GO:0005006 epidermal growth factor receptor activity 7/1801 50/18639 0.14 1.44889505830094 0.204651896805873 0.701413765975685 GO:0005007 fibroblast growth factor receptor activity 7/1801 50/18639 0.14 1.44889505830094 0.204651896805873 0.701413765975685 GO:0005548 phospholipid transporter activity 9/1801 68/18639 0.132352941176471 1.36975373158703 0.207465818937827 0.707029405615315 GO:0030145 manganese ion binding 9/1801 68/18639 0.132352941176471 1.36975373158703 0.207465818937827 0.707029405615315 GO:0019956 chemokine binding 5/1801 33/18639 0.151515151515152 1.56806824491444 0.209541486486705 0.712085898992956 GO:0033218 amide binding 28/1801 247/18639 0.11336032388664 1.17319437919105 0.212183310716401 0.718901751725808 GO:0008017 microtubule binding 31/1801 276/18639 0.11231884057971 1.1624158076431 0.212742330519025 0.718901751725808 GO:0019894 kinesin binding 6/1801 42/18639 0.142857142857143 1.47846434520504 0.215930609764803 0.72559922778508 GO:0042056 chemoattractant activity 6/1801 42/18639 0.142857142857143 1.47846434520504 0.215930609764803 0.72559922778508 GO:0005537 D-mannose binding 4/1801 25/18639 0.16 1.65588006662965 0.217845895068115 0.725951833149426 GO:0019211 phosphatase activator activity 4/1801 25/18639 0.16 1.65588006662965 0.217845895068115 0.725951833149426 GO:0042974 nuclear retinoic acid receptor binding 4/1801 25/18639 0.16 1.65588006662965 0.217845895068115 0.725951833149426 GO:0001098 basal transcription machinery binding 8/1801 60/18639 0.133333333333333 1.37990005552471 0.219953247863747 0.728935970193079 GO:0001099 basal RNA polymerase II transcription machinery binding 8/1801 60/18639 0.133333333333333 1.37990005552471 0.219953247863747 0.728935970193079 GO:0004549 tRNA-specific ribonuclease activity 3/1801 17/18639 0.176470588235294 1.8263383087827 0.222521862174123 0.731403825670684 GO:0046965 nuclear retinoid X receptor binding 3/1801 17/18639 0.176470588235294 1.8263383087827 0.222521862174123 0.731403825670684 GO:0070492 oligosaccharide binding 3/1801 17/18639 0.176470588235294 1.8263383087827 0.222521862174123 0.731403825670684 GO:0019903 protein phosphatase binding 17/1801 144/18639 0.118055555555556 1.22178650749584 0.226632371070387 0.738156894897421 GO:0000287 magnesium ion binding 26/1801 230/18639 0.11304347826087 1.1699152644666 0.226792147245071 0.738156894897421 GO:0008376 acetylgalactosaminyltransferase activity 5/1801 34/18639 0.147058823529412 1.52194859065225 0.227644395683245 0.738156894897421 GO:0051427 hormone receptor binding 5/1801 34/18639 0.147058823529412 1.52194859065225 0.227644395683245 0.738156894897421 GO:0090482 vitamin transmembrane transporter activity 5/1801 34/18639 0.147058823529412 1.52194859065225 0.227644395683245 0.738156894897421 GO:0005506 iron ion binding 18/1801 154/18639 0.116883116883117 1.20965264607685 0.231064250645793 0.73961131400106 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6/1801 43/18639 0.13953488372093 1.44408145345609 0.232061712328138 0.73961131400106 GO:0097110 scaffold protein binding 9/1801 70/18639 0.128571428571429 1.33061791068454 0.232169630452996 0.73961131400106 GO:0008198 ferrous iron binding 4/1801 26/18639 0.153846153846154 1.59219237175928 0.239292257869948 0.73961131400106 GO:0015216 purine nucleotide transmembrane transporter activity 4/1801 26/18639 0.153846153846154 1.59219237175928 0.239292257869948 0.73961131400106 GO:0097602 cullin family protein binding 4/1801 26/18639 0.153846153846154 1.59219237175928 0.239292257869948 0.73961131400106 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 38/1801 349/18639 0.108882521489971 1.12685248087261 0.240912332596928 0.73961131400106 GO:0016229 steroid dehydrogenase activity 5/1801 35/18639 0.142857142857143 1.47846434520504 0.246180490323175 0.73961131400106 GO:0005246 calcium channel regulator activity 7/1801 53/18639 0.132075471698113 1.36688213047259 0.248536644001546 0.73961131400106 GO:0030547 signaling receptor inhibitor activity 6/1801 44/18639 0.136363636363636 1.411261420423 0.248553377385088 0.73961131400106 GO:0000400 four-way junction DNA binding 3/1801 18/18639 0.166666666666667 1.72487506940589 0.249249709912336 0.73961131400106 GO:0008308 voltage-gated monoatomic anion channel activity 3/1801 18/18639 0.166666666666667 1.72487506940589 0.249249709912336 0.73961131400106 GO:0008525 phosphatidylcholine transporter activity 3/1801 18/18639 0.166666666666667 1.72487506940589 0.249249709912336 0.73961131400106 GO:0030228 lipoprotein particle receptor activity 3/1801 18/18639 0.166666666666667 1.72487506940589 0.249249709912336 0.73961131400106 GO:0031690 adrenergic receptor binding 3/1801 18/18639 0.166666666666667 1.72487506940589 0.249249709912336 0.73961131400106 GO:0034185 apolipoprotein binding 3/1801 18/18639 0.166666666666667 1.72487506940589 0.249249709912336 0.73961131400106 GO:1901611 phosphatidylglycerol binding 3/1801 18/18639 0.166666666666667 1.72487506940589 0.249249709912336 0.73961131400106 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0005345 purine nucleobase transmembrane transporter activity 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0008140 cAMP response element binding protein binding 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0008239 dipeptidyl-peptidase activity 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0030957 Tat protein binding 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0031957 very long-chain fatty acid-CoA ligase activity 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0033204 ribonuclease P RNA binding 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0043422 protein kinase B binding 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0051880 G-quadruplex DNA binding 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0097177 mitochondrial ribosome binding 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0140940 histone H2A methyltransferase activity 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0141109 transporter activator activity 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:1990259 histone H2AQ104 methyltransferase activity 2/1801 10/18639 0.2 2.06985008328706 0.250840744898115 0.73961131400106 GO:0001671 ATPase activator activity 4/1801 27/18639 0.148148148148148 1.53322228391634 0.261195352618513 0.766385388292855 GO:0023026 MHC class II protein complex binding 4/1801 27/18639 0.148148148148148 1.53322228391634 0.261195352618513 0.766385388292855 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 11/1801 91/18639 0.120879120879121 1.25100829209658 0.262012899119069 0.76691366822443 GO:0140463 chromatin-protein adaptor activity 7/1801 54/18639 0.12962962962963 1.3415694984268 0.263768411885018 0.767384730871025 GO:0004033 aldo-keto reductase (NADPH) activity 5/1801 36/18639 0.138888888888889 1.43739589117157 0.265087998515618 0.767384730871025 GO:0004869 cysteine-type endopeptidase inhibitor activity 5/1801 36/18639 0.138888888888889 1.43739589117157 0.265087998515618 0.767384730871025 GO:0044390 ubiquitin-like protein conjugating enzyme binding 5/1801 36/18639 0.138888888888889 1.43739589117157 0.265087998515618 0.767384730871025 GO:0042605 peptide antigen binding 6/1801 45/18639 0.133333333333333 1.37990005552471 0.265363298455816 0.767384730871025 GO:0016247 channel regulator activity 19/1801 168/18639 0.113095238095238 1.17045093995399 0.268616927635744 0.774930848790888 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 3/1801 19/18639 0.157894736842105 1.6340921710161 0.27641516318082 0.781031119658904 GO:0005520 insulin-like growth factor binding 3/1801 19/18639 0.157894736842105 1.6340921710161 0.27641516318082 0.781031119658904 GO:0046527 glucosyltransferase activity 3/1801 19/18639 0.157894736842105 1.6340921710161 0.27641516318082 0.781031119658904 GO:0070003 threonine-type peptidase activity 3/1801 19/18639 0.157894736842105 1.6340921710161 0.27641516318082 0.781031119658904 GO:0140036 ubiquitin-modified protein reader activity 3/1801 19/18639 0.157894736842105 1.6340921710161 0.27641516318082 0.781031119658904 GO:0030414 peptidase inhibitor activity 19/1801 169/18639 0.112426035502959 1.16352519474717 0.277275268136533 0.781031119658904 GO:0004540 RNA nuclease activity 14/1801 121/18639 0.115702479338843 1.19743393248012 0.278823358041123 0.781031119658904 GO:0019842 vitamin binding 17/1801 150/18639 0.113333333333333 1.172915047196 0.280317102678475 0.781031119658904 GO:0046966 nuclear thyroid hormone receptor binding 4/1801 28/18639 0.142857142857143 1.47846434520504 0.283457232345127 0.781031119658904 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 4/1801 28/18639 0.142857142857143 1.47846434520504 0.283457232345127 0.781031119658904 GO:0051213 dioxygenase activity 11/1801 93/18639 0.118279569892473 1.22410488796547 0.285671917932645 0.781031119658904 GO:0141108 transporter regulator activity 19/1801 170/18639 0.111764705882353 1.15668092889571 0.286030785507046 0.781031119658904 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 2/1801 11/18639 0.181818181818182 1.88168189389733 0.288260862118498 0.781031119658904 GO:0002162 dystroglycan binding 2/1801 11/18639 0.181818181818182 1.88168189389733 0.288260862118498 0.781031119658904 GO:0003953 NAD+ nucleosidase activity 2/1801 11/18639 0.181818181818182 1.88168189389733 0.288260862118498 0.781031119658904 GO:0004016 adenylate cyclase activity 2/1801 11/18639 0.181818181818182 1.88168189389733 0.288260862118498 0.781031119658904 GO:0004523 RNA-DNA hybrid ribonuclease activity 2/1801 11/18639 0.181818181818182 1.88168189389733 0.288260862118498 0.781031119658904 GO:0008046 axon guidance receptor activity 2/1801 11/18639 0.181818181818182 1.88168189389733 0.288260862118498 0.781031119658904 GO:0008526 phosphatidylinositol transfer activity 2/1801 11/18639 0.181818181818182 1.88168189389733 0.288260862118498 0.781031119658904 GO:0015205 nucleobase transmembrane transporter activity 2/1801 11/18639 0.181818181818182 1.88168189389733 0.288260862118498 0.781031119658904 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/1801 11/18639 0.181818181818182 1.88168189389733 0.288260862118498 0.781031119658904 GO:0042608 T cell receptor binding 2/1801 11/18639 0.181818181818182 1.88168189389733 0.288260862118498 0.781031119658904 GO:0043522 leucine zipper domain binding 2/1801 11/18639 0.181818181818182 1.88168189389733 0.288260862118498 0.781031119658904 GO:0045294 alpha-catenin binding 2/1801 11/18639 0.181818181818182 1.88168189389733 0.288260862118498 0.781031119658904 GO:0047676 arachidonate-CoA ligase activity 2/1801 11/18639 0.181818181818182 1.88168189389733 0.288260862118498 0.781031119658904 GO:0048185 activin binding 2/1801 11/18639 0.181818181818182 1.88168189389733 0.288260862118498 0.781031119658904 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/1801 11/18639 0.181818181818182 1.88168189389733 0.288260862118498 0.781031119658904 GO:0038024 cargo receptor activity 8/1801 65/18639 0.123076923076923 1.27375389740742 0.289763874582441 0.781582827629319 GO:0120013 lipid transfer activity 8/1801 65/18639 0.123076923076923 1.27375389740742 0.289763874582441 0.781582827629319 GO:0004866 endopeptidase inhibitor activity 18/1801 161/18639 0.111801242236025 1.15705905276917 0.292434244669961 0.787021020890297 GO:0001784 phosphotyrosine residue binding 6/1801 47/18639 0.127659574468085 1.32118090422578 0.299767366300647 0.798476460123177 GO:0043495 protein-membrane adaptor activity 6/1801 47/18639 0.127659574468085 1.32118090422578 0.299767366300647 0.798476460123177 GO:0046982 protein heterodimerization activity 39/1801 369/18639 0.105691056910569 1.0938232147452 0.300365475390165 0.798476460123177 GO:0005109 frizzled binding 5/1801 38/18639 0.131578947368421 1.36174347584675 0.303771812205419 0.798476460123177 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 3/1801 20/18639 0.15 1.5523875624653 0.303844770316621 0.798476460123177 GO:0015095 magnesium ion transmembrane transporter activity 3/1801 20/18639 0.15 1.5523875624653 0.303844770316621 0.798476460123177 GO:0016004 phospholipase activator activity 3/1801 20/18639 0.15 1.5523875624653 0.303844770316621 0.798476460123177 GO:0016408 C-acyltransferase activity 3/1801 20/18639 0.15 1.5523875624653 0.303844770316621 0.798476460123177 GO:0016505 peptidase activator activity involved in apoptotic process 3/1801 20/18639 0.15 1.5523875624653 0.303844770316621 0.798476460123177 GO:0031418 L-ascorbic acid binding 3/1801 20/18639 0.15 1.5523875624653 0.303844770316621 0.798476460123177 GO:0008235 metalloexopeptidase activity 8/1801 66/18639 0.121212121212121 1.25445459593155 0.304365049733243 0.798476460123177 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 4/1801 29/18639 0.137931034482759 1.42748281606004 0.305983082391342 0.798476460123177 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 4/1801 29/18639 0.137931034482759 1.42748281606004 0.305983082391342 0.798476460123177 GO:0097472 cyclin-dependent protein kinase activity 4/1801 29/18639 0.137931034482759 1.42748281606004 0.305983082391342 0.798476460123177 GO:0015932 nucleobase-containing compound transmembrane transporter activity 7/1801 57/18639 0.12280701754386 1.27096057745697 0.310836147746568 0.809385034067361 GO:0016879 ligase activity, forming carbon-nitrogen bonds 6/1801 48/18639 0.125 1.29365630205441 0.317276516240002 0.812351201511715 GO:0017124 SH3 domain binding 13/1801 115/18639 0.11304347826087 1.1699152644666 0.318047281320389 0.812351201511715 GO:0035401 histone H3Y41 kinase activity 13/1801 115/18639 0.11304347826087 1.1699152644666 0.318047281320389 0.812351201511715 GO:0140801 histone H2AXY142 kinase activity 13/1801 115/18639 0.11304347826087 1.1699152644666 0.318047281320389 0.812351201511715 GO:0008237 metallopeptidase activity 20/1801 184/18639 0.108695652173913 1.12491852352558 0.323386496028558 0.812351201511715 GO:0004300 enoyl-CoA hydratase activity 2/1801 12/18639 0.166666666666667 1.72487506940589 0.325447756469583 0.812351201511715 GO:0005078 MAP-kinase scaffold activity 2/1801 12/18639 0.166666666666667 1.72487506940589 0.325447756469583 0.812351201511715 GO:0005165 neurotrophin receptor binding 2/1801 12/18639 0.166666666666667 1.72487506940589 0.325447756469583 0.812351201511715 GO:0016423 tRNA (guanine) methyltransferase activity 2/1801 12/18639 0.166666666666667 1.72487506940589 0.325447756469583 0.812351201511715 GO:0036009 protein-glutamine N-methyltransferase activity 2/1801 12/18639 0.166666666666667 1.72487506940589 0.325447756469583 0.812351201511715 GO:0045295 gamma-catenin binding 2/1801 12/18639 0.166666666666667 1.72487506940589 0.325447756469583 0.812351201511715 GO:0070008 serine-type exopeptidase activity 2/1801 12/18639 0.166666666666667 1.72487506940589 0.325447756469583 0.812351201511715 GO:0097677 STAT family protein binding 2/1801 12/18639 0.166666666666667 1.72487506940589 0.325447756469583 0.812351201511715 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/1801 12/18639 0.166666666666667 1.72487506940589 0.325447756469583 0.812351201511715 GO:1990459 transferrin receptor binding 2/1801 12/18639 0.166666666666667 1.72487506940589 0.325447756469583 0.812351201511715 GO:0001965 G-protein alpha-subunit binding 4/1801 30/18639 0.133333333333333 1.37990005552471 0.32868197543475 0.812351201511715 GO:0031210 phosphatidylcholine binding 4/1801 30/18639 0.133333333333333 1.37990005552471 0.32868197543475 0.812351201511715 GO:0035925 mRNA 3'-UTR AU-rich region binding 4/1801 30/18639 0.133333333333333 1.37990005552471 0.32868197543475 0.812351201511715 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/1801 21/18639 0.142857142857143 1.47846434520504 0.331378975019779 0.812351201511715 GO:0001846 opsonin binding 3/1801 21/18639 0.142857142857143 1.47846434520504 0.331378975019779 0.812351201511715 GO:0008373 sialyltransferase activity 3/1801 21/18639 0.142857142857143 1.47846434520504 0.331378975019779 0.812351201511715 GO:0009975 cyclase activity 3/1801 21/18639 0.142857142857143 1.47846434520504 0.331378975019779 0.812351201511715 GO:0051428 peptide hormone receptor binding 3/1801 21/18639 0.142857142857143 1.47846434520504 0.331378975019779 0.812351201511715 GO:0140312 cargo adaptor activity 3/1801 21/18639 0.142857142857143 1.47846434520504 0.331378975019779 0.812351201511715 GO:0005004 GPI-linked ephrin receptor activity 6/1801 49/18639 0.122448979591837 1.2672551530329 0.334934493723866 0.812351201511715 GO:0005008 hepatocyte growth factor receptor activity 6/1801 49/18639 0.122448979591837 1.2672551530329 0.334934493723866 0.812351201511715 GO:0005009 insulin receptor activity 6/1801 49/18639 0.122448979591837 1.2672551530329 0.334934493723866 0.812351201511715 GO:0005011 macrophage colony-stimulating factor receptor activity 6/1801 49/18639 0.122448979591837 1.2672551530329 0.334934493723866 0.812351201511715 GO:0005018 platelet-derived growth factor alpha-receptor activity 6/1801 49/18639 0.122448979591837 1.2672551530329 0.334934493723866 0.812351201511715 GO:0005020 stem cell factor receptor activity 6/1801 49/18639 0.122448979591837 1.2672551530329 0.334934493723866 0.812351201511715 GO:0008288 boss receptor activity 6/1801 49/18639 0.122448979591837 1.2672551530329 0.334934493723866 0.812351201511715 GO:0036332 placental growth factor receptor activity 6/1801 49/18639 0.122448979591837 1.2672551530329 0.334934493723866 0.812351201511715 GO:0038062 protein tyrosine kinase collagen receptor activity 6/1801 49/18639 0.122448979591837 1.2672551530329 0.334934493723866 0.812351201511715 GO:0060175 brain-derived neurotrophic factor receptor activity 6/1801 49/18639 0.122448979591837 1.2672551530329 0.334934493723866 0.812351201511715 GO:0031593 polyubiquitin modification-dependent protein binding 7/1801 59/18639 0.11864406779661 1.22787716805165 0.343041693481707 0.830340356656929 GO:0042626 ATPase-coupled transmembrane transporter activity 11/1801 98/18639 0.112244897959184 1.16165055694682 0.34714538141561 0.838586132214818 GO:0031406 carboxylic acid binding 20/1801 187/18639 0.106951871657754 1.10687170229255 0.350327957884687 0.844578223116791 GO:0005017 platelet-derived growth factor receptor activity 6/1801 50/18639 0.12 1.24191004997224 0.352700302394502 0.845831068150699 GO:0005019 platelet-derived growth factor beta-receptor activity 6/1801 50/18639 0.12 1.24191004997224 0.352700302394502 0.845831068150699 GO:0033293 monocarboxylic acid binding 9/1801 79/18639 0.113924050632911 1.17902852845466 0.353514775306732 0.845831068150699 GO:0008649 rRNA methyltransferase activity 3/1801 22/18639 0.136363636363636 1.411261420423 0.358872548825688 0.845831068150699 GO:0034062 5'-3' RNA polymerase activity 3/1801 22/18639 0.136363636363636 1.411261420423 0.358872548825688 0.845831068150699 GO:0097747 RNA polymerase activity 3/1801 22/18639 0.136363636363636 1.411261420423 0.358872548825688 0.845831068150699 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 7/1801 60/18639 0.116666666666667 1.20741254858412 0.359298657997286 0.845831068150699 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 7/1801 60/18639 0.116666666666667 1.20741254858412 0.359298657997286 0.845831068150699 GO:0140597 protein carrier chaperone 20/1801 188/18639 0.106382978723404 1.10098408685482 0.359417693935418 0.845831068150699 GO:0005542 folic acid binding 2/1801 13/18639 0.153846153846154 1.59219237175928 0.362097256938994 0.845831068150699 GO:0015651 quaternary ammonium group transmembrane transporter activity 2/1801 13/18639 0.153846153846154 1.59219237175928 0.362097256938994 0.845831068150699 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 2/1801 13/18639 0.153846153846154 1.59219237175928 0.362097256938994 0.845831068150699 GO:0017154 semaphorin receptor activity 2/1801 13/18639 0.153846153846154 1.59219237175928 0.362097256938994 0.845831068150699 GO:0031994 insulin-like growth factor I binding 2/1801 13/18639 0.153846153846154 1.59219237175928 0.362097256938994 0.845831068150699 GO:0045159 myosin II binding 2/1801 13/18639 0.153846153846154 1.59219237175928 0.362097256938994 0.845831068150699 GO:0061459 L-arginine transmembrane transporter activity 2/1801 13/18639 0.153846153846154 1.59219237175928 0.362097256938994 0.845831068150699 GO:0043177 organic acid binding 20/1801 189/18639 0.105820105820106 1.09515877422596 0.368553315645614 0.858867749904049 GO:0005010 insulin-like growth factor receptor activity 6/1801 51/18639 0.117647058823529 1.2175588725218 0.370533966916211 0.858867749904049 GO:0005021 vascular endothelial growth factor receptor activity 6/1801 51/18639 0.117647058823529 1.2175588725218 0.370533966916211 0.858867749904049 GO:0005030 neurotrophin receptor activity 6/1801 51/18639 0.117647058823529 1.2175588725218 0.370533966916211 0.858867749904049 GO:0043130 ubiquitin binding 11/1801 100/18639 0.11 1.13841754580788 0.372369807285318 0.860701241559672 GO:0015106 bicarbonate transmembrane transporter activity 4/1801 32/18639 0.125 1.29365630205441 0.374258086996198 0.860701241559672 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/1801 32/18639 0.125 1.29365630205441 0.374258086996198 0.860701241559672 GO:0042910 xenobiotic transmembrane transporter activity 4/1801 32/18639 0.125 1.29365630205441 0.374258086996198 0.860701241559672 GO:0032182 ubiquitin-like protein binding 13/1801 120/18639 0.108333333333333 1.12116879511383 0.375135714854669 0.860701241559672 GO:0016836 hydro-lyase activity 7/1801 61/18639 0.114754098360656 1.18761890024668 0.375617748810331 0.860701241559672 GO:0019902 phosphatase binding 20/1801 190/18639 0.105263157894737 1.0893947806774 0.377729543031647 0.863894753359452 GO:0048487 beta-tubulin binding 5/1801 42/18639 0.119047619047619 1.2320536210042 0.382962967432031 0.868880594701333 GO:1902936 phosphatidylinositol bisphosphate binding 12/1801 111/18639 0.108108108108108 1.11883788285787 0.386044830771975 0.868880594701333 GO:0008171 O-methyltransferase activity 3/1801 23/18639 0.130434782608696 1.34990222823069 0.386194666225148 0.868880594701333 GO:0016849 phosphorus-oxygen lyase activity 3/1801 23/18639 0.130434782608696 1.34990222823069 0.386194666225148 0.868880594701333 GO:0031681 G-protein beta-subunit binding 3/1801 23/18639 0.130434782608696 1.34990222823069 0.386194666225148 0.868880594701333 GO:0099186 structural constituent of postsynapse 3/1801 23/18639 0.130434782608696 1.34990222823069 0.386194666225148 0.868880594701333 GO:0140102 catalytic activity, acting on a rRNA 3/1801 23/18639 0.130434782608696 1.34990222823069 0.386194666225148 0.868880594701333 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 6/1801 52/18639 0.115384615384615 1.19414427881946 0.388396726836081 0.868880594701333 GO:0005539 glycosaminoglycan binding 25/1801 242/18639 0.103305785123967 1.06913743971439 0.393034964165853 0.868880594701333 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 4/1801 33/18639 0.121212121212121 1.25445459593155 0.396977618100956 0.868880594701333 GO:0140416 transcription regulator inhibitor activity 4/1801 33/18639 0.121212121212121 1.25445459593155 0.396977618100956 0.868880594701333 GO:0052689 carboxylic ester hydrolase activity 10/1801 92/18639 0.108695652173913 1.12491852352558 0.397096183118048 0.868880594701333 GO:0005161 platelet-derived growth factor receptor binding 2/1801 14/18639 0.142857142857143 1.47846434520504 0.397966091172431 0.868880594701333 GO:0005545 1-phosphatidylinositol binding 2/1801 14/18639 0.142857142857143 1.47846434520504 0.397966091172431 0.868880594701333 GO:0008474 palmitoyl-(protein) hydrolase activity 2/1801 14/18639 0.142857142857143 1.47846434520504 0.397966091172431 0.868880594701333 GO:0008494 translation activator activity 2/1801 14/18639 0.142857142857143 1.47846434520504 0.397966091172431 0.868880594701333 GO:0008559 ABC-type xenobiotic transporter activity 2/1801 14/18639 0.142857142857143 1.47846434520504 0.397966091172431 0.868880594701333 GO:0019992 diacylglycerol binding 2/1801 14/18639 0.142857142857143 1.47846434520504 0.397966091172431 0.868880594701333 GO:0046030 inositol trisphosphate phosphatase activity 2/1801 14/18639 0.142857142857143 1.47846434520504 0.397966091172431 0.868880594701333 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 2/1801 14/18639 0.142857142857143 1.47846434520504 0.397966091172431 0.868880594701333 GO:0070742 C2H2 zinc finger domain binding 2/1801 14/18639 0.142857142857143 1.47846434520504 0.397966091172431 0.868880594701333 GO:0071933 Arp2/3 complex binding 2/1801 14/18639 0.142857142857143 1.47846434520504 0.397966091172431 0.868880594701333 GO:0098599 palmitoyl hydrolase activity 2/1801 14/18639 0.142857142857143 1.47846434520504 0.397966091172431 0.868880594701333 GO:1901474 azole transmembrane transporter activity 2/1801 14/18639 0.142857142857143 1.47846434520504 0.397966091172431 0.868880594701333 GO:1901612 cardiolipin binding 2/1801 14/18639 0.142857142857143 1.47846434520504 0.397966091172431 0.868880594701333 GO:0016251 RNA polymerase II general transcription initiation factor activity 6/1801 53/18639 0.113207547169811 1.17161325469079 0.40625120549581 0.883761664035188 GO:0038064 collagen receptor activity 6/1801 53/18639 0.113207547169811 1.17161325469079 0.40625120549581 0.883761664035188 GO:0001540 amyloid-beta binding 9/1801 83/18639 0.108433734939759 1.12220787648094 0.41023065305576 0.886121439596862 GO:0004722 protein serine/threonine phosphatase activity 11/1801 103/18639 0.106796116504854 1.10525975321154 0.410535263961597 0.886121439596862 GO:0015295 solute:proton symporter activity 3/1801 24/18639 0.125 1.29365630205441 0.413228701258387 0.886121439596862 GO:0042625 ATPase-coupled ion transmembrane transporter activity 3/1801 24/18639 0.125 1.29365630205441 0.413228701258387 0.886121439596862 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 3/1801 24/18639 0.125 1.29365630205441 0.413228701258387 0.886121439596862 GO:0046961 proton-transporting ATPase activity, rotational mechanism 3/1801 24/18639 0.125 1.29365630205441 0.413228701258387 0.886121439596862 GO:0060229 lipase activator activity 3/1801 24/18639 0.125 1.29365630205441 0.413228701258387 0.886121439596862 GO:0070840 dynein complex binding 3/1801 24/18639 0.125 1.29365630205441 0.413228701258387 0.886121439596862 GO:0008175 tRNA methyltransferase activity 4/1801 34/18639 0.117647058823529 1.2175588725218 0.419555381089984 0.898087408276247 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 6/1801 54/18639 0.111111111111111 1.14991671293726 0.424061554697159 0.905341187738078 GO:0004527 exonuclease activity 9/1801 84/18639 0.107142857142857 1.10884825890378 0.424449235149024 0.905341187738078 GO:1901981 phosphatidylinositol phosphate binding 19/1801 185/18639 0.102702702702703 1.06289598871498 0.425325014275217 0.905603525970063 GO:0004467 long-chain fatty acid-CoA ligase activity 2/1801 15/18639 0.133333333333333 1.37990005552471 0.432862967031452 0.911968737896386 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/1801 15/18639 0.133333333333333 1.37990005552471 0.432862967031452 0.911968737896386 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/1801 15/18639 0.133333333333333 1.37990005552471 0.432862967031452 0.911968737896386 GO:0031005 filamin binding 2/1801 15/18639 0.133333333333333 1.37990005552471 0.432862967031452 0.911968737896386 GO:0042809 nuclear vitamin D receptor binding 2/1801 15/18639 0.133333333333333 1.37990005552471 0.432862967031452 0.911968737896386 GO:0050700 CARD domain binding 2/1801 15/18639 0.133333333333333 1.37990005552471 0.432862967031452 0.911968737896386 GO:0015662 P-type ion transporter activity 3/1801 25/18639 0.12 1.24191004997224 0.439871811193423 0.918690605669598 GO:0017025 TBP-class protein binding 3/1801 25/18639 0.12 1.24191004997224 0.439871811193423 0.918690605669598 GO:0019706 protein-cysteine S-palmitoyltransferase activity 3/1801 25/18639 0.12 1.24191004997224 0.439871811193423 0.918690605669598 GO:0019707 protein-cysteine S-acyltransferase activity 3/1801 25/18639 0.12 1.24191004997224 0.439871811193423 0.918690605669598 GO:0140358 P-type transmembrane transporter activity 3/1801 25/18639 0.12 1.24191004997224 0.439871811193423 0.918690605669598 GO:0140566 histone reader activity 4/1801 35/18639 0.114285714285714 1.18277147616404 0.441926334737315 0.921381942268613 GO:0050660 flavin adenine dinucleotide binding 9/1801 86/18639 0.104651162790698 1.08306109009207 0.452805655851956 0.940316401293986 GO:0030291 protein serine/threonine kinase inhibitor activity 5/1801 46/18639 0.108695652173913 1.12491852352558 0.461737996758932 0.940316401293986 GO:0016409 palmitoyltransferase activity 4/1801 36/18639 0.111111111111111 1.14991671293726 0.464031126765027 0.940316401293986 GO:0030507 spectrin binding 3/1801 26/18639 0.115384615384615 1.19414427881946 0.466034361626921 0.940316401293986 GO:0050681 nuclear androgen receptor binding 3/1801 26/18639 0.115384615384615 1.19414427881946 0.466034361626921 0.940316401293986 GO:0070412 R-SMAD binding 3/1801 26/18639 0.115384615384615 1.19414427881946 0.466034361626921 0.940316401293986 GO:0120014 phospholipid transfer activity 3/1801 26/18639 0.115384615384615 1.19414427881946 0.466034361626921 0.940316401293986 GO:0000062 fatty-acyl-CoA binding 2/1801 16/18639 0.125 1.29365630205441 0.466640807624696 0.940316401293986 GO:0003688 DNA replication origin binding 2/1801 16/18639 0.125 1.29365630205441 0.466640807624696 0.940316401293986 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 2/1801 16/18639 0.125 1.29365630205441 0.466640807624696 0.940316401293986 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/1801 16/18639 0.125 1.29365630205441 0.466640807624696 0.940316401293986 GO:0004708 MAP kinase kinase activity 2/1801 16/18639 0.125 1.29365630205441 0.466640807624696 0.940316401293986 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1801 16/18639 0.125 1.29365630205441 0.466640807624696 0.940316401293986 GO:0005521 lamin binding 2/1801 16/18639 0.125 1.29365630205441 0.466640807624696 0.940316401293986 GO:0008296 3'-5'-DNA exonuclease activity 2/1801 16/18639 0.125 1.29365630205441 0.466640807624696 0.940316401293986 GO:0034450 ubiquitin-ubiquitin ligase activity 2/1801 16/18639 0.125 1.29365630205441 0.466640807624696 0.940316401293986 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/1801 16/18639 0.125 1.29365630205441 0.466640807624696 0.940316401293986 GO:0055102 lipase inhibitor activity 2/1801 16/18639 0.125 1.29365630205441 0.466640807624696 0.940316401293986 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/1801 16/18639 0.125 1.29365630205441 0.466640807624696 0.940316401293986 GO:0070411 I-SMAD binding 2/1801 16/18639 0.125 1.29365630205441 0.466640807624696 0.940316401293986 GO:0008173 RNA methyltransferase activity 7/1801 67/18639 0.104477611940299 1.0812649688813 0.473240989023514 0.950432236720012 GO:0016500 protein-hormone receptor activity 7/1801 67/18639 0.104477611940299 1.0812649688813 0.473240989023514 0.950432236720012 GO:0140359 ABC-type transporter activity 5/1801 47/18639 0.106382978723404 1.10098408685482 0.481020214670632 0.963698171704398 GO:0099106 ion channel regulator activity 16/1801 160/18639 0.1 1.03492504164353 0.481448546296212 0.963698171704398 GO:0023023 MHC protein complex binding 4/1801 37/18639 0.108108108108108 1.11883788285787 0.485816066720033 0.969215138083249 GO:0042805 actinin binding 4/1801 37/18639 0.108108108108108 1.11883788285787 0.485816066720033 0.969215138083249 GO:0140223 general transcription initiation factor activity 7/1801 68/18639 0.102941176470588 1.06536401345658 0.489218404915885 0.974386988599022 GO:0008266 poly(U) RNA binding 3/1801 27/18639 0.111111111111111 1.14991671293726 0.491639237752972 0.974879172764256 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 3/1801 27/18639 0.111111111111111 1.14991671293726 0.491639237752972 0.974879172764256 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 2/1801 17/18639 0.117647058823529 1.2175588725218 0.499190000351439 0.974879172764256 GO:0004659 prenyltransferase activity 2/1801 17/18639 0.117647058823529 1.2175588725218 0.499190000351439 0.974879172764256 GO:0005092 GDP-dissociation inhibitor activity 2/1801 17/18639 0.117647058823529 1.2175588725218 0.499190000351439 0.974879172764256 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/1801 17/18639 0.117647058823529 1.2175588725218 0.499190000351439 0.974879172764256 GO:0017110 nucleoside diphosphate phosphatase activity 2/1801 17/18639 0.117647058823529 1.2175588725218 0.499190000351439 0.974879172764256 GO:0030548 acetylcholine receptor regulator activity 2/1801 17/18639 0.117647058823529 1.2175588725218 0.499190000351439 0.974879172764256 GO:0031489 myosin V binding 2/1801 17/18639 0.117647058823529 1.2175588725218 0.499190000351439 0.974879172764256 GO:0036041 long-chain fatty acid binding 2/1801 17/18639 0.117647058823529 1.2175588725218 0.499190000351439 0.974879172764256 GO:0070402 NADPH binding 2/1801 17/18639 0.117647058823529 1.2175588725218 0.499190000351439 0.974879172764256 GO:1901567 fatty acid derivative binding 2/1801 17/18639 0.117647058823529 1.2175588725218 0.499190000351439 0.974879172764256 GO:0008236 serine-type peptidase activity 19/1801 194/18639 0.0979381443298969 1.01358638099109 0.510996182981474 0.995330909592857 GO:0070063 RNA polymerase binding 6/1801 59/18639 0.101694915254237 1.05246614404427 0.511317125626256 0.995330909592857 GO:0050698 proteoglycan sulfotransferase activity 3/1801 28/18639 0.107142857142857 1.10884825890378 0.516621078401913 0.99999999998166 GO:0051393 alpha-actinin binding 3/1801 28/18639 0.107142857142857 1.10884825890378 0.516621078401913 0.99999999998166 GO:0016763 pentosyltransferase activity 5/1801 49/18639 0.102040816326531 1.05604596086075 0.518824462090854 0.99999999998166 GO:0033192 calmodulin-dependent protein phosphatase activity 8/1801 81/18639 0.0987654320987654 1.02214818927756 0.528837704326855 0.99999999998166 GO:0140791 histone H2AXS140 phosphatase activity 8/1801 81/18639 0.0987654320987654 1.02214818927756 0.528837704326855 0.99999999998166 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 8/1801 81/18639 0.0987654320987654 1.02214818927756 0.528837704326855 0.99999999998166 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 8/1801 81/18639 0.0987654320987654 1.02214818927756 0.528837704326855 0.99999999998166 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 8/1801 81/18639 0.0987654320987654 1.02214818927756 0.528837704326855 0.99999999998166 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 8/1801 81/18639 0.0987654320987654 1.02214818927756 0.528837704326855 0.99999999998166 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 8/1801 81/18639 0.0987654320987654 1.02214818927756 0.528837704326855 0.99999999998166 GO:1990439 MAP kinase serine/threonine phosphatase activity 8/1801 81/18639 0.0987654320987654 1.02214818927756 0.528837704326855 0.99999999998166 GO:0008514 organic anion transmembrane transporter activity 26/1801 269/18639 0.0966542750929368 1.00029929675583 0.52997772041816 0.99999999998166 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/1801 18/18639 0.111111111111111 1.14991671293726 0.530432536656328 0.99999999998166 GO:0035615 clathrin adaptor activity 2/1801 18/18639 0.111111111111111 1.14991671293726 0.530432536656328 0.99999999998166 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 2/1801 18/18639 0.111111111111111 1.14991671293726 0.530432536656328 0.99999999998166 GO:0070064 proline-rich region binding 2/1801 18/18639 0.111111111111111 1.14991671293726 0.530432536656328 0.99999999998166 GO:0099602 neurotransmitter receptor regulator activity 2/1801 18/18639 0.111111111111111 1.14991671293726 0.530432536656328 0.99999999998166 GO:0004175 endopeptidase activity 39/1801 405/18639 0.0962962962962963 0.996594484545623 0.534234132540311 0.99999999998166 GO:0015605 organophosphate ester transmembrane transporter activity 5/1801 50/18639 0.1 1.03492504164353 0.537282702057116 0.99999999998166 GO:0004252 serine-type endopeptidase activity 17/1801 176/18639 0.0965909090909091 0.999643506132956 0.538241611410049 0.99999999998166 GO:0004629 phospholipase C activity 3/1801 29/18639 0.103448275862069 1.07061211204503 0.540925462556979 0.99999999998166 GO:0016417 S-acyltransferase activity 3/1801 29/18639 0.103448275862069 1.07061211204503 0.540925462556979 0.99999999998166 GO:0106222 lncRNA binding 3/1801 29/18639 0.103448275862069 1.07061211204503 0.540925462556979 0.99999999998166 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 8/1801 82/18639 0.0975609756097561 1.0096829674571 0.54319755042233 0.99999999998166 GO:0033549 MAP kinase phosphatase activity 8/1801 82/18639 0.0975609756097561 1.0096829674571 0.54319755042233 0.99999999998166 GO:0015297 antiporter activity 13/1801 135/18639 0.0962962962962963 0.996594484545623 0.548028390411299 0.99999999998166 GO:0017171 serine hydrolase activity 19/1801 198/18639 0.095959595959596 0.993109888445813 0.548261810990957 0.99999999998166 GO:0030331 nuclear estrogen receptor binding 4/1801 40/18639 0.1 1.03492504164353 0.548797600092269 0.99999999998166 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 8/1801 83/18639 0.0963855421686747 0.9975181124275 0.557380686141431 0.99999999998166 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/1801 19/18639 0.105263157894737 1.0893947806774 0.560316933535799 0.99999999998166 GO:0008381 mechanosensitive monoatomic ion channel activity 2/1801 19/18639 0.105263157894737 1.0893947806774 0.560316933535799 0.99999999998166 GO:0008574 plus-end-directed microtubule motor activity 2/1801 19/18639 0.105263157894737 1.0893947806774 0.560316933535799 0.99999999998166 GO:0015245 fatty acid transmembrane transporter activity 2/1801 19/18639 0.105263157894737 1.0893947806774 0.560316933535799 0.99999999998166 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/1801 19/18639 0.105263157894737 1.0893947806774 0.560316933535799 0.99999999998166 GO:0120227 acyl-CoA binding 2/1801 19/18639 0.105263157894737 1.0893947806774 0.560316933535799 0.99999999998166 GO:1990380 K48-linked deubiquitinase activity 2/1801 19/18639 0.105263157894737 1.0893947806774 0.560316933535799 0.99999999998166 GO:0101005 deubiquitinase activity 11/1801 115/18639 0.0956521739130435 0.989928300702508 0.560520213820741 0.99999999998166 GO:0051020 GTPase binding 30/1801 315/18639 0.0952380952380952 0.985642896803363 0.561895236339732 0.99999999998166 GO:0008187 poly-pyrimidine tract binding 3/1801 30/18639 0.1 1.03492504164353 0.564508072237227 0.99999999998166 GO:0031624 ubiquitin conjugating enzyme binding 3/1801 30/18639 0.1 1.03492504164353 0.564508072237227 0.99999999998166 GO:0048019 receptor antagonist activity 3/1801 30/18639 0.1 1.03492504164353 0.564508072237227 0.99999999998166 GO:0098918 structural constituent of synapse 3/1801 30/18639 0.1 1.03492504164353 0.564508072237227 0.99999999998166 GO:0004521 RNA endonuclease activity 7/1801 73/18639 0.0958904109589041 0.992393875548592 0.566512045178796 0.99999999998166 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/1801 41/18639 0.0975609756097561 1.0096829674571 0.568875377080856 0.99999999998166 GO:0016877 ligase activity, forming carbon-sulfur bonds 4/1801 41/18639 0.0975609756097561 1.0096829674571 0.568875377080856 0.99999999998166 GO:0017080 sodium channel regulator activity 4/1801 41/18639 0.0975609756097561 1.0096829674571 0.568875377080856 0.99999999998166 GO:0140828 metal cation:monoatomic cation antiporter activity 4/1801 41/18639 0.0975609756097561 1.0096829674571 0.568875377080856 0.99999999998166 GO:0017018 myosin phosphatase activity 8/1801 84/18639 0.0952380952380952 0.985642896803363 0.571373470456421 0.99999999998166 GO:0030159 signaling receptor complex adaptor activity 5/1801 52/18639 0.0961538461538462 0.995120232349549 0.573174674969915 0.99999999998166 GO:0004867 serine-type endopeptidase inhibitor activity 9/1801 95/18639 0.0947368421052632 0.980455302609661 0.575905213404797 0.99999999998166 GO:0019783 ubiquitin-like protein peptidase activity 12/1801 127/18639 0.094488188976378 0.977881929111998 0.576809890509465 0.99999999998166 GO:0042826 histone deacetylase binding 12/1801 127/18639 0.094488188976378 0.977881929111998 0.576809890509465 0.99999999998166 GO:0005126 cytokine receptor binding 26/1801 275/18639 0.0945454545454545 0.978474584826612 0.577126974589538 0.99999999998166 GO:1901681 sulfur compound binding 26/1801 275/18639 0.0945454545454545 0.978474584826612 0.577126974589538 0.99999999998166 GO:1901682 sulfur compound transmembrane transporter activity 6/1801 63/18639 0.0952380952380952 0.985642896803363 0.577330628426695 0.99999999998166 GO:0008327 methyl-CpG binding 3/1801 31/18639 0.0967741935483871 1.00154036288084 0.587333850739256 0.99999999998166 GO:0016878 acid-thiol ligase activity 3/1801 31/18639 0.0967741935483871 1.00154036288084 0.587333850739256 0.99999999998166 GO:0047499 calcium-independent phospholipase A2 activity 3/1801 31/18639 0.0967741935483871 1.00154036288084 0.587333850739256 0.99999999998166 GO:0070273 phosphatidylinositol-4-phosphate binding 3/1801 31/18639 0.0967741935483871 1.00154036288084 0.587333850739256 0.99999999998166 GO:0031490 chromatin DNA binding 12/1801 128/18639 0.09375 0.970242226540811 0.588040518710858 0.99999999998166 GO:0015291 secondary active transmembrane transporter activity 27/1801 287/18639 0.0940766550522648 0.973622861476493 0.588223896673287 0.99999999998166 GO:0035198 miRNA binding 4/1801 42/18639 0.0952380952380952 0.985642896803363 0.588445104412311 0.99999999998166 GO:0005326 neurotransmitter transmembrane transporter activity 2/1801 20/18639 0.1 1.03492504164353 0.588813840560153 0.99999999998166 GO:0061608 nuclear import signal receptor activity 2/1801 20/18639 0.1 1.03492504164353 0.588813840560153 0.99999999998166 GO:1901505 carbohydrate derivative transmembrane transporter activity 5/1801 53/18639 0.0943396226415094 0.976344378908992 0.590562536373468 0.99999999998166 GO:0070851 growth factor receptor binding 13/1801 139/18639 0.0935251798561151 0.967915506573087 0.591710777273916 0.99999999998166 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 8/1801 86/18639 0.0930232558139535 0.962720968970727 0.598738396798922 0.99999999998166 GO:0003714 transcription corepressor activity 19/1801 204/18639 0.0931372549019608 0.96390077407976 0.60233761385377 0.99999999998166 GO:0004712 protein serine/threonine/tyrosine kinase activity 4/1801 43/18639 0.0930232558139535 0.962720968970727 0.60748374119971 0.99999999998166 GO:0050661 NADP binding 5/1801 54/18639 0.0925925925925926 0.958263927447714 0.607552432462887 0.99999999998166 GO:0043425 bHLH transcription factor binding 3/1801 32/18639 0.09375 0.970242226540811 0.609376171126469 0.99999999998166 GO:0047498 calcium-dependent phospholipase A2 activity 3/1801 32/18639 0.09375 0.970242226540811 0.609376171126469 0.99999999998166 GO:0071813 lipoprotein particle binding 3/1801 32/18639 0.09375 0.970242226540811 0.609376171126469 0.99999999998166 GO:0071814 protein-lipid complex binding 3/1801 32/18639 0.09375 0.970242226540811 0.609376171126469 0.99999999998166 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/1801 21/18639 0.0952380952380952 0.985642896803363 0.615912247459139 0.99999999998166 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/1801 21/18639 0.0952380952380952 0.985642896803363 0.615912247459139 0.99999999998166 GO:0015174 basic amino acid transmembrane transporter activity 2/1801 21/18639 0.0952380952380952 0.985642896803363 0.615912247459139 0.99999999998166 GO:0070182 DNA polymerase binding 2/1801 21/18639 0.0952380952380952 0.985642896803363 0.615912247459139 0.99999999998166 GO:0001046 core promoter sequence-specific DNA binding 4/1801 44/18639 0.0909090909090909 0.940840946948665 0.62597251910065 0.99999999998166 GO:0016790 thiolester hydrolase activity 4/1801 44/18639 0.0909090909090909 0.940840946948665 0.62597251910065 0.99999999998166 GO:0004222 metalloendopeptidase activity 10/1801 110/18639 0.0909090909090909 0.940840946948665 0.628079716126284 0.99999999998166 GO:0140311 protein sequestering activity 3/1801 33/18639 0.0909090909090909 0.940840946948665 0.63061602642902 0.99999999998166 GO:0000182 rDNA binding 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0004382 GDP phosphatase activity 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0004955 prostaglandin receptor activity 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0005131 growth hormone receptor binding 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0005337 nucleoside transmembrane transporter activity 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0015203 polyamine transmembrane transporter activity 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0015643 toxic substance binding 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0016427 tRNA (cytidine) methyltransferase activity 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0016783 sulfurtransferase activity 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0016868 intramolecular phosphotransferase activity 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0019531 oxalate transmembrane transporter activity 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0019911 structural constituent of myelin sheath 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0031434 mitogen-activated protein kinase kinase binding 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0032052 bile acid binding 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0032356 oxidized DNA binding 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0035374 chondroitin sulfate binding 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0042975 peroxisome proliferator activated receptor binding 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0043121 neurotrophin binding 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0098505 G-rich strand telomeric DNA binding 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0099122 RNA polymerase II C-terminal domain binding 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0140135 mechanosensitive monoatomic cation channel activity 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:1905394 retromer complex binding 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/1801 10/18639 0.1 1.03492504164353 0.638118169175073 0.99999999998166 GO:0016881 acid-amino acid ligase activity 2/1801 22/18639 0.0909090909090909 0.940840946948665 0.641616217322484 0.99999999998166 GO:0050321 tau-protein kinase activity 2/1801 22/18639 0.0909090909090909 0.940840946948665 0.641616217322484 0.99999999998166 GO:0140784 metal ion sensor activity 2/1801 22/18639 0.0909090909090909 0.940840946948665 0.641616217322484 0.99999999998166 GO:0004715 non-membrane spanning protein tyrosine kinase activity 4/1801 45/18639 0.0888888888888889 0.919933370349806 0.643896662900018 0.99999999998166 GO:0051539 4 iron, 4 sulfur cluster binding 4/1801 45/18639 0.0888888888888889 0.919933370349806 0.643896662900018 0.99999999998166 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 3/1801 34/18639 0.0882352941176471 0.913169154391351 0.651041250171507 0.99999999998166 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 3/1801 34/18639 0.0882352941176471 0.913169154391351 0.651041250171507 0.99999999998166 GO:0030332 cyclin binding 3/1801 34/18639 0.0882352941176471 0.913169154391351 0.651041250171507 0.99999999998166 GO:0052866 phosphatidylinositol phosphate phosphatase activity 3/1801 34/18639 0.0882352941176471 0.913169154391351 0.651041250171507 0.99999999998166 GO:0072341 modified amino acid binding 8/1801 91/18639 0.0879120879120879 0.909824212433874 0.663054741816423 0.99999999998166 GO:0016493 C-C chemokine receptor activity 2/1801 23/18639 0.0869565217391304 0.899934818820462 0.665942079331755 0.99999999998166 GO:0042171 lysophosphatidic acid acyltransferase activity 2/1801 23/18639 0.0869565217391304 0.899934818820462 0.665942079331755 0.99999999998166 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/1801 23/18639 0.0869565217391304 0.899934818820462 0.665942079331755 0.99999999998166 GO:0071617 lysophospholipid acyltransferase activity 2/1801 23/18639 0.0869565217391304 0.899934818820462 0.665942079331755 0.99999999998166 GO:0004623 phospholipase A2 activity 3/1801 35/18639 0.0857142857142857 0.887078607123027 0.670645773493463 0.99999999998166 GO:0000099 sulfur amino acid transmembrane transporter activity 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0004954 prostanoid receptor activity 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0005114 type II transforming growth factor beta receptor binding 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0008199 ferric iron binding 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0008271 secondary active sulfate transmembrane transporter activity 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0008432 JUN kinase binding 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0008503 benzodiazepine receptor activity 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0015173 aromatic amino acid transmembrane transporter activity 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0019107 myristoyltransferase activity 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0019206 nucleoside kinase activity 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0019215 intermediate filament binding 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0032050 clathrin heavy chain binding 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0034056 estrogen response element binding 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0035252 UDP-xylosyltransferase activity 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0042285 xylosyltransferase activity 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0070697 activin receptor binding 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0140537 transcription regulator activator activity 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0180030 inositol phosphate kinase activity 1/1801 11/18639 0.0909090909090909 0.940840946948665 0.673103899880731 0.99999999998166 GO:0005253 monoatomic anion channel activity 9/1801 103/18639 0.087378640776699 0.904303434445804 0.673759863698342 0.99999999998166 GO:0015101 organic cation transmembrane transporter activity 7/1801 81/18639 0.0864197530864197 0.894379665617867 0.677382868117163 0.99999999998166 GO:0061749 forked DNA-dependent helicase activity 4/1801 47/18639 0.0851063829787234 0.880787269483857 0.678010213584991 0.99999999998166 GO:1990518 single-stranded 3'-5' DNA helicase activity 4/1801 47/18639 0.0851063829787234 0.880787269483857 0.678010213584991 0.99999999998166 GO:0008028 monocarboxylic acid transmembrane transporter activity 6/1801 70/18639 0.0857142857142857 0.887078607123027 0.680817327304586 0.99999999998166 GO:0001786 phosphatidylserine binding 5/1801 59/18639 0.0847457627118644 0.877055120036891 0.686057482502417 0.99999999998166 GO:0004879 nuclear receptor activity 5/1801 59/18639 0.0847457627118644 0.877055120036891 0.686057482502417 0.99999999998166 GO:0015459 potassium channel regulator activity 5/1801 59/18639 0.0847457627118644 0.877055120036891 0.686057482502417 0.99999999998166 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/1801 24/18639 0.0833333333333333 0.862437534702943 0.68891602279297 0.99999999998166 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/1801 24/18639 0.0833333333333333 0.862437534702943 0.68891602279297 0.99999999998166 GO:0004622 lysophospholipase activity 2/1801 24/18639 0.0833333333333333 0.862437534702943 0.68891602279297 0.99999999998166 GO:0005315 phosphate transmembrane transporter activity 2/1801 24/18639 0.0833333333333333 0.862437534702943 0.68891602279297 0.99999999998166 GO:0015149 hexose transmembrane transporter activity 2/1801 24/18639 0.0833333333333333 0.862437534702943 0.68891602279297 0.99999999998166 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/1801 24/18639 0.0833333333333333 0.862437534702943 0.68891602279297 0.99999999998166 GO:0019957 C-C chemokine binding 2/1801 24/18639 0.0833333333333333 0.862437534702943 0.68891602279297 0.99999999998166 GO:0030215 semaphorin receptor binding 2/1801 24/18639 0.0833333333333333 0.862437534702943 0.68891602279297 0.99999999998166 GO:0055056 D-glucose transmembrane transporter activity 2/1801 24/18639 0.0833333333333333 0.862437534702943 0.68891602279297 0.99999999998166 GO:0005484 SNAP receptor activity 3/1801 36/18639 0.0833333333333333 0.862437534702943 0.689428923196049 0.99999999998166 GO:0009378 four-way junction helicase activity 4/1801 48/18639 0.0833333333333333 0.862437534702943 0.694187489401406 0.99999999998166 GO:0036121 double-stranded DNA helicase activity 4/1801 48/18639 0.0833333333333333 0.862437534702943 0.694187489401406 0.99999999998166 GO:0043138 3'-5' DNA helicase activity 4/1801 48/18639 0.0833333333333333 0.862437534702943 0.694187489401406 0.99999999998166 GO:0008201 heparin binding 15/1801 172/18639 0.0872093023255814 0.902550908410056 0.70020763785641 0.99999999998166 GO:0098531 ligand-modulated transcription factor activity 5/1801 60/18639 0.0833333333333333 0.862437534702943 0.700407429414099 0.99999999998166 GO:0030165 PDZ domain binding 7/1801 83/18639 0.0843373493975904 0.872828348374063 0.70211318655891 0.99999999998166 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0003720 telomerase activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0004000 adenosine deaminase activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0004032 aldose reductase (NADPH) activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0004126 cytidine deaminase activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0004859 phospholipase inhibitor activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0004875 complement receptor activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0005025 transforming growth factor beta receptor activity, type I 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0005026 transforming growth factor beta receptor activity, type II 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0005095 GTPase inhibitor activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0008603 cAMP-dependent protein kinase regulator activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0015132 prostaglandin transmembrane transporter activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0016273 arginine N-methyltransferase activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0016274 protein-arginine N-methyltransferase activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0016361 activin receptor activity, type I 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0016362 activin receptor activity, type II 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0017002 activin receptor activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0034452 dynactin binding 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0035497 cAMP response element binding 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0043047 single-stranded telomeric DNA binding 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/1801 12/18639 0.0833333333333333 0.862437534702943 0.704709003827199 0.99999999998166 GO:0030551 cyclic nucleotide binding 3/1801 37/18639 0.0810810810810811 0.839128412143404 0.707394763473344 0.99999999998166 GO:0043394 proteoglycan binding 3/1801 37/18639 0.0810810810810811 0.839128412143404 0.707394763473344 0.99999999998166 GO:0000030 mannosyltransferase activity 2/1801 25/18639 0.08 0.827940033314825 0.710572041192931 0.99999999998166 GO:0001848 complement binding 2/1801 25/18639 0.08 0.827940033314825 0.710572041192931 0.99999999998166 GO:0008139 nuclear localization sequence binding 2/1801 25/18639 0.08 0.827940033314825 0.710572041192931 0.99999999998166 GO:0008483 transaminase activity 2/1801 25/18639 0.08 0.827940033314825 0.710572041192931 0.99999999998166 GO:0015645 fatty acid ligase activity 2/1801 25/18639 0.08 0.827940033314825 0.710572041192931 0.99999999998166 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/1801 25/18639 0.08 0.827940033314825 0.710572041192931 0.99999999998166 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 2/1801 25/18639 0.08 0.827940033314825 0.710572041192931 0.99999999998166 GO:0047617 fatty acyl-CoA hydrolase activity 2/1801 25/18639 0.08 0.827940033314825 0.710572041192931 0.99999999998166 GO:0120515 fatty acid-CoA ligase activity 2/1801 25/18639 0.08 0.827940033314825 0.710572041192931 0.99999999998166 GO:0019905 syntaxin binding 5/1801 61/18639 0.0819672131147541 0.848299214461911 0.714296103205865 0.99999999998166 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 20/1801 229/18639 0.0873362445414847 0.903864665190857 0.716219260122186 0.99999999998166 GO:0035173 histone kinase activity 32/1801 360/18639 0.0888888888888889 0.919933370349806 0.717829377381634 0.99999999998166 GO:0004896 cytokine receptor activity 8/1801 96/18639 0.0833333333333333 0.862437534702943 0.720803947994781 0.99999999998166 GO:0005501 retinoid binding 3/1801 38/18639 0.0789473684210526 0.817046085508051 0.724551482813397 0.99999999998166 GO:0019840 isoprenoid binding 3/1801 38/18639 0.0789473684210526 0.817046085508051 0.724551482813397 0.99999999998166 GO:0004721 phosphoprotein phosphatase activity 15/1801 175/18639 0.0857142857142857 0.887078607123027 0.725065233805504 0.99999999998166 GO:0004843 cysteine-type deubiquitinase activity 9/1801 108/18639 0.0833333333333333 0.862437534702943 0.727473020850486 0.99999999998166 GO:0004518 nuclease activity 18/1801 209/18639 0.0861244019138756 0.891323002372419 0.730915217810156 0.99999999998166 GO:0001637 G protein-coupled chemoattractant receptor activity 2/1801 26/18639 0.0769230769230769 0.79609618587964 0.730950181156765 0.99999999998166 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/1801 26/18639 0.0769230769230769 0.79609618587964 0.730950181156765 0.99999999998166 GO:0004435 phosphatidylinositol phospholipase C activity 2/1801 26/18639 0.0769230769230769 0.79609618587964 0.730950181156765 0.99999999998166 GO:0004529 DNA exonuclease activity 2/1801 26/18639 0.0769230769230769 0.79609618587964 0.730950181156765 0.99999999998166 GO:0004950 chemokine receptor activity 2/1801 26/18639 0.0769230769230769 0.79609618587964 0.730950181156765 0.99999999998166 GO:0008157 protein phosphatase 1 binding 2/1801 26/18639 0.0769230769230769 0.79609618587964 0.730950181156765 0.99999999998166 GO:0015145 monosaccharide transmembrane transporter activity 2/1801 26/18639 0.0769230769230769 0.79609618587964 0.730950181156765 0.99999999998166 GO:0016289 acyl-CoA hydrolase activity 2/1801 26/18639 0.0769230769230769 0.79609618587964 0.730950181156765 0.99999999998166 GO:0034237 protein kinase A regulatory subunit binding 2/1801 26/18639 0.0769230769230769 0.79609618587964 0.730950181156765 0.99999999998166 GO:0001664 G protein-coupled receptor binding 26/1801 297/18639 0.0875420875420875 0.905994985950566 0.731517532407763 0.99999999998166 GO:0003678 DNA helicase activity 6/1801 74/18639 0.0810810810810811 0.839128412143404 0.731947032649721 0.99999999998166 GO:0002161 aminoacyl-tRNA editing activity 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0003964 RNA-directed DNA polymerase activity 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0009982 pseudouridine synthase activity 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0030955 potassium ion binding 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0035325 Toll-like receptor binding 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0035673 oligopeptide transmembrane transporter activity 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0039706 co-receptor binding 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0046974 histone H3K9 methyltransferase activity 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0070123 transforming growth factor beta receptor activity, type III 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0071714 icosanoid transmembrane transporter activity 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0071837 HMG box domain binding 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0097157 pre-mRNA intronic binding 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0140666 annealing activity 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0140852 histone ubiquitin ligase activity 1/1801 13/18639 0.0769230769230769 0.79609618587964 0.733259982734549 0.99999999998166 GO:0004620 phospholipase activity 9/1801 109/18639 0.0825688073394495 0.854525263742365 0.737472478782365 0.99999999998166 GO:0004386 helicase activity 13/1801 155/18639 0.0838709677419355 0.868001647830059 0.744143375559108 0.99999999998166 GO:0141003 histone H2AX kinase activity 31/1801 354/18639 0.0875706214689266 0.906290290704787 0.745373875763721 0.99999999998166 GO:0008081 phosphoric diester hydrolase activity 7/1801 87/18639 0.0804597701149425 0.832698309368359 0.747710309751961 0.99999999998166 GO:0016405 CoA-ligase activity 2/1801 27/18639 0.0740740740740741 0.766611141958171 0.750095056629068 0.99999999998166 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/1801 27/18639 0.0740740740740741 0.766611141958171 0.750095056629068 0.99999999998166 GO:0004536 DNA nuclease activity 5/1801 64/18639 0.078125 0.808535188784009 0.753192669904277 0.99999999998166 GO:0032451 demethylase activity 3/1801 40/18639 0.075 0.776193781232648 0.756487574625491 0.99999999998166 GO:0071855 neuropeptide receptor binding 3/1801 40/18639 0.075 0.776193781232648 0.756487574625491 0.99999999998166 GO:0008174 mRNA methyltransferase activity 1/1801 14/18639 0.0714285714285714 0.739232172602522 0.759051820547019 0.99999999998166 GO:0015926 glucosidase activity 1/1801 14/18639 0.0714285714285714 0.739232172602522 0.759051820547019 0.99999999998166 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/1801 14/18639 0.0714285714285714 0.739232172602522 0.759051820547019 0.99999999998166 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/1801 14/18639 0.0714285714285714 0.739232172602522 0.759051820547019 0.99999999998166 GO:0031404 chloride ion binding 1/1801 14/18639 0.0714285714285714 0.739232172602522 0.759051820547019 0.99999999998166 GO:0032454 histone H3K9 demethylase activity 1/1801 14/18639 0.0714285714285714 0.739232172602522 0.759051820547019 0.99999999998166 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/1801 14/18639 0.0714285714285714 0.739232172602522 0.759051820547019 0.99999999998166 GO:0042043 neurexin family protein binding 1/1801 14/18639 0.0714285714285714 0.739232172602522 0.759051820547019 0.99999999998166 GO:0098821 BMP receptor activity 1/1801 14/18639 0.0714285714285714 0.739232172602522 0.759051820547019 0.99999999998166 GO:0140996 histone H3 kinase activity 31/1801 357/18639 0.0868347338935574 0.898674405908949 0.761587719037747 0.99999999998166 GO:0015293 symporter activity 12/1801 146/18639 0.0821917808219178 0.850623321898793 0.762940253099831 0.99999999998166 GO:0005544 calcium-dependent phospholipid binding 4/1801 53/18639 0.0754716981132075 0.781075503127194 0.766285523973883 0.99999999998166 GO:0008146 sulfotransferase activity 4/1801 53/18639 0.0754716981132075 0.781075503127194 0.766285523973883 0.99999999998166 GO:0051018 protein kinase A binding 4/1801 53/18639 0.0754716981132075 0.781075503127194 0.766285523973883 0.99999999998166 GO:0140097 catalytic activity, acting on DNA 29/1801 336/18639 0.0863095238095238 0.893238875228048 0.766707157910597 0.99999999998166 GO:0016866 intramolecular transferase activity 2/1801 28/18639 0.0714285714285714 0.739232172602522 0.768054593415772 0.99999999998166 GO:0019789 SUMO transferase activity 2/1801 28/18639 0.0714285714285714 0.739232172602522 0.768054593415772 0.99999999998166 GO:0045499 chemorepellent activity 2/1801 28/18639 0.0714285714285714 0.739232172602522 0.768054593415772 0.99999999998166 GO:0051019 mitogen-activated protein kinase binding 2/1801 28/18639 0.0714285714285714 0.739232172602522 0.768054593415772 0.99999999998166 GO:0051119 sugar transmembrane transporter activity 2/1801 28/18639 0.0714285714285714 0.739232172602522 0.768054593415772 0.99999999998166 GO:0051959 dynein light intermediate chain binding 2/1801 28/18639 0.0714285714285714 0.739232172602522 0.768054593415772 0.99999999998166 GO:0141052 histone H3 demethylase activity 2/1801 28/18639 0.0714285714285714 0.739232172602522 0.768054593415772 0.99999999998166 GO:0016779 nucleotidyltransferase activity 11/1801 136/18639 0.0808823529411765 0.837071724858739 0.774435008335521 0.99999999998166 GO:0015171 amino acid transmembrane transporter activity 8/1801 102/18639 0.0784313725490196 0.811705915014534 0.780834946365374 0.99999999998166 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1801 15/18639 0.0666666666666667 0.689950027762354 0.78235102436956 0.99999999998166 GO:0004953 icosanoid receptor activity 1/1801 15/18639 0.0666666666666667 0.689950027762354 0.78235102436956 0.99999999998166 GO:0005523 tropomyosin binding 1/1801 15/18639 0.0666666666666667 0.689950027762354 0.78235102436956 0.99999999998166 GO:0008020 G protein-coupled photoreceptor activity 1/1801 15/18639 0.0666666666666667 0.689950027762354 0.78235102436956 0.99999999998166 GO:0008242 omega peptidase activity 1/1801 15/18639 0.0666666666666667 0.689950027762354 0.78235102436956 0.99999999998166 GO:0010181 FMN binding 1/1801 15/18639 0.0666666666666667 0.689950027762354 0.78235102436956 0.99999999998166 GO:0015116 sulfate transmembrane transporter activity 1/1801 15/18639 0.0666666666666667 0.689950027762354 0.78235102436956 0.99999999998166 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1801 15/18639 0.0666666666666667 0.689950027762354 0.78235102436956 0.99999999998166 GO:0017081 chloride channel regulator activity 1/1801 15/18639 0.0666666666666667 0.689950027762354 0.78235102436956 0.99999999998166 GO:0030553 cGMP binding 1/1801 15/18639 0.0666666666666667 0.689950027762354 0.78235102436956 0.99999999998166 GO:0045504 dynein heavy chain binding 1/1801 15/18639 0.0666666666666667 0.689950027762354 0.78235102436956 0.99999999998166 GO:0051371 muscle alpha-actinin binding 1/1801 15/18639 0.0666666666666667 0.689950027762354 0.78235102436956 0.99999999998166 GO:0140776 protein-containing complex destabilizing activity 1/1801 15/18639 0.0666666666666667 0.689950027762354 0.78235102436956 0.99999999998166 GO:0141050 histone H3K deacetylase activity 1/1801 15/18639 0.0666666666666667 0.689950027762354 0.78235102436956 0.99999999998166 GO:0141051 histone H4K deacetylase activity 1/1801 15/18639 0.0666666666666667 0.689950027762354 0.78235102436956 0.99999999998166 GO:0099604 ligand-gated calcium channel activity 2/1801 29/18639 0.0689655172413793 0.713741408030022 0.784878973479386 0.99999999998166 GO:0004520 DNA endonuclease activity 3/1801 42/18639 0.0714285714285714 0.739232172602522 0.785364753097102 0.99999999998166 GO:0004519 endonuclease activity 10/1801 127/18639 0.078740157480315 0.814901607593332 0.794909811880626 0.99999999998166 GO:0003777 microtubule motor activity 5/1801 68/18639 0.0735294117647059 0.760974295326126 0.798705510322479 0.99999999998166 GO:1990841 promoter-specific chromatin binding 5/1801 68/18639 0.0735294117647059 0.760974295326126 0.798705510322479 0.99999999998166 GO:0015294 solute:monoatomic cation symporter activity 9/1801 116/18639 0.0775862068965517 0.802959084033774 0.800426249153516 0.99999999998166 GO:0032452 histone demethylase activity 2/1801 30/18639 0.0666666666666667 0.689950027762354 0.800619752139541 0.99999999998166 GO:0051721 protein phosphatase 2A binding 2/1801 30/18639 0.0666666666666667 0.689950027762354 0.800619752139541 0.99999999998166 GO:0005024 transforming growth factor beta receptor activity 1/1801 16/18639 0.0625 0.646828151027207 0.803398372152551 0.99999999998166 GO:0005149 interleukin-1 receptor binding 1/1801 16/18639 0.0625 0.646828151027207 0.803398372152551 0.99999999998166 GO:0015562 efflux transmembrane transporter activity 1/1801 16/18639 0.0625 0.646828151027207 0.803398372152551 0.99999999998166 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1801 16/18639 0.0625 0.646828151027207 0.803398372152551 0.99999999998166 GO:0016722 oxidoreductase activity, acting on metal ions 1/1801 16/18639 0.0625 0.646828151027207 0.803398372152551 0.99999999998166 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/1801 16/18639 0.0625 0.646828151027207 0.803398372152551 0.99999999998166 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/1801 16/18639 0.0625 0.646828151027207 0.803398372152551 0.99999999998166 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/1801 16/18639 0.0625 0.646828151027207 0.803398372152551 0.99999999998166 GO:0002039 p53 binding 5/1801 69/18639 0.072463768115942 0.749945682350385 0.808987654045506 0.99999999998166 GO:0140713 histone chaperone activity 13/1801 164/18639 0.0792682926829268 0.820367411058897 0.811054346268403 0.99999999998166 GO:0001223 transcription coactivator binding 3/1801 44/18639 0.0681818181818182 0.705630710211499 0.811344851664193 0.99999999998166 GO:0043014 alpha-tubulin binding 3/1801 44/18639 0.0681818181818182 0.705630710211499 0.811344851664193 0.99999999998166 GO:0008094 ATP-dependent activity, acting on DNA 17/1801 210/18639 0.080952380952381 0.837796462282859 0.811866695647361 0.99999999998166 GO:0000149 SNARE binding 8/1801 106/18639 0.0754716981132075 0.781075503127194 0.815243237411291 0.99999999998166 GO:0005164 tumor necrosis factor receptor binding 2/1801 31/18639 0.0645161290322581 0.667693575253891 0.815329124649905 0.99999999998166 GO:0005184 neuropeptide hormone activity 2/1801 31/18639 0.0645161290322581 0.667693575253891 0.815329124649905 0.99999999998166 GO:0005310 dicarboxylic acid transmembrane transporter activity 2/1801 31/18639 0.0645161290322581 0.667693575253891 0.815329124649905 0.99999999998166 GO:0005452 solute:inorganic anion antiporter activity 2/1801 31/18639 0.0645161290322581 0.667693575253891 0.815329124649905 0.99999999998166 GO:0016411 acylglycerol O-acyltransferase activity 2/1801 31/18639 0.0645161290322581 0.667693575253891 0.815329124649905 0.99999999998166 GO:0017147 Wnt-protein binding 2/1801 31/18639 0.0645161290322581 0.667693575253891 0.815329124649905 0.99999999998166 GO:0072349 modified amino acid transmembrane transporter activity 2/1801 31/18639 0.0645161290322581 0.667693575253891 0.815329124649905 0.99999999998166 GO:0140457 protein demethylase activity 2/1801 31/18639 0.0645161290322581 0.667693575253891 0.815329124649905 0.99999999998166 GO:0016298 lipase activity 10/1801 130/18639 0.0769230769230769 0.79609618587964 0.817658621023814 0.99999999998166 GO:0016782 transferase activity, transferring sulphur-containing groups 5/1801 70/18639 0.0714285714285714 0.739232172602522 0.818846909948654 0.99999999998166 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/1801 17/18639 0.0588235294117647 0.608779436260901 0.82241139539012 0.99999999998166 GO:0008429 phosphatidylethanolamine binding 1/1801 17/18639 0.0588235294117647 0.608779436260901 0.82241139539012 0.99999999998166 GO:0009881 photoreceptor activity 1/1801 17/18639 0.0588235294117647 0.608779436260901 0.82241139539012 0.99999999998166 GO:0015278 intracellularly gated calcium channel activity 1/1801 17/18639 0.0588235294117647 0.608779436260901 0.82241139539012 0.99999999998166 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/1801 17/18639 0.0588235294117647 0.608779436260901 0.82241139539012 0.99999999998166 GO:0019198 transmembrane receptor protein phosphatase activity 1/1801 17/18639 0.0588235294117647 0.608779436260901 0.82241139539012 0.99999999998166 GO:0030169 low-density lipoprotein particle binding 1/1801 17/18639 0.0588235294117647 0.608779436260901 0.82241139539012 0.99999999998166 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/1801 17/18639 0.0588235294117647 0.608779436260901 0.82241139539012 0.99999999998166 GO:0032183 SUMO binding 1/1801 17/18639 0.0588235294117647 0.608779436260901 0.82241139539012 0.99999999998166 GO:0038191 neuropilin binding 1/1801 17/18639 0.0588235294117647 0.608779436260901 0.82241139539012 0.99999999998166 GO:0070403 NAD+ binding 1/1801 17/18639 0.0588235294117647 0.608779436260901 0.82241139539012 0.99999999998166 GO:1990226 histone methyltransferase binding 1/1801 17/18639 0.0588235294117647 0.608779436260901 0.82241139539012 0.99999999998166 GO:0008276 protein methyltransferase activity 7/1801 95/18639 0.0736842105263158 0.762576346474181 0.823469915257966 0.99999999998166 GO:0017116 single-stranded DNA helicase activity 4/1801 58/18639 0.0689655172413793 0.713741408030022 0.824369082334976 0.99999999998166 GO:0061980 regulatory RNA binding 4/1801 58/18639 0.0689655172413793 0.713741408030022 0.824369082334976 0.99999999998166 GO:0042393 histone binding 20/1801 247/18639 0.0809716599190283 0.837995985136463 0.827561031211445 0.99999999998166 GO:0140299 molecular sensor activity 5/1801 71/18639 0.0704225352112676 0.728820451861642 0.828292312557144 0.99999999998166 GO:0160041 neuropeptide activity 2/1801 32/18639 0.0625 0.646828151027207 0.829059321551467 0.99999999998166 GO:0016874 ligase activity 13/1801 167/18639 0.0778443113772455 0.805630271938078 0.830243923671161 0.99999999998166 GO:0005179 hormone activity 10/1801 132/18639 0.0757575757575758 0.784034122457221 0.831732304925018 0.99999999998166 GO:0036002 pre-mRNA binding 4/1801 59/18639 0.0677966101694915 0.701644096029513 0.834428107777344 0.99999999998166 GO:0004180 carboxypeptidase activity 3/1801 46/18639 0.0652173913043478 0.674951114115346 0.834611971176956 0.99999999998166 GO:0000900 mRNA regulatory element binding translation repressor activity 1/1801 18/18639 0.0555555555555556 0.574958356468629 0.839586622374461 0.99999999998166 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/1801 18/18639 0.0555555555555556 0.574958356468629 0.839586622374461 0.99999999998166 GO:0004970 glutamate-gated receptor activity 1/1801 18/18639 0.0555555555555556 0.574958356468629 0.839586622374461 0.99999999998166 GO:0008409 5'-3' exonuclease activity 1/1801 18/18639 0.0555555555555556 0.574958356468629 0.839586622374461 0.99999999998166 GO:0016854 racemase and epimerase activity 1/1801 18/18639 0.0555555555555556 0.574958356468629 0.839586622374461 0.99999999998166 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/1801 18/18639 0.0555555555555556 0.574958356468629 0.839586622374461 0.99999999998166 GO:0017075 syntaxin-1 binding 1/1801 18/18639 0.0555555555555556 0.574958356468629 0.839586622374461 0.99999999998166 GO:0017128 phospholipid scramblase activity 1/1801 18/18639 0.0555555555555556 0.574958356468629 0.839586622374461 0.99999999998166 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/1801 18/18639 0.0555555555555556 0.574958356468629 0.839586622374461 0.99999999998166 GO:0050811 GABA receptor binding 1/1801 18/18639 0.0555555555555556 0.574958356468629 0.839586622374461 0.99999999998166 GO:0016741 transferase activity, transferring one-carbon groups 17/1801 215/18639 0.0790697674418605 0.818312823625118 0.839713865694302 0.99999999998166 GO:0019239 deaminase activity 2/1801 33/18639 0.0606060606060606 0.627227297965777 0.841862114785174 0.99999999998166 GO:0030296 protein tyrosine kinase activator activity 2/1801 33/18639 0.0606060606060606 0.627227297965777 0.841862114785174 0.99999999998166 GO:0071889 14-3-3 protein binding 2/1801 33/18639 0.0606060606060606 0.627227297965777 0.841862114785174 0.99999999998166 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 14/1801 181/18639 0.0773480662983425 0.800494507348588 0.843945037078602 0.99999999998166 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 4/1801 60/18639 0.0666666666666667 0.689950027762354 0.844001013374719 0.99999999998166 GO:0140658 ATP-dependent chromatin remodeler activity 12/1801 158/18639 0.0759493670886076 0.786019018969771 0.846621259330692 0.99999999998166 GO:0140098 catalytic activity, acting on RNA 32/1801 387/18639 0.082687338501292 0.855751972418424 0.847733290672867 0.99999999998166 GO:0015085 calcium ion transmembrane transporter activity 11/1801 147/18639 0.0748299319727891 0.774433704631214 0.851638402097901 0.99999999998166 GO:0004674 protein serine/threonine kinase activity 36/1801 433/18639 0.0831408775981524 0.860445762105476 0.852205487513776 0.99999999998166 GO:0015026 coreceptor activity 4/1801 61/18639 0.0655737704918033 0.678639371569529 0.853103112333937 0.99999999998166 GO:0015020 glucuronosyltransferase activity 2/1801 34/18639 0.0588235294117647 0.608779436260901 0.853788418823528 0.99999999998166 GO:0005229 intracellularly calcium-gated chloride channel activity 1/1801 19/18639 0.0526315789473684 0.544697390338701 0.85510160508772 0.99999999998166 GO:0016918 retinal binding 1/1801 19/18639 0.0526315789473684 0.544697390338701 0.85510160508772 0.99999999998166 GO:0031420 alkali metal ion binding 1/1801 19/18639 0.0526315789473684 0.544697390338701 0.85510160508772 0.99999999998166 GO:0042577 lipid phosphatase activity 1/1801 19/18639 0.0526315789473684 0.544697390338701 0.85510160508772 0.99999999998166 GO:0042834 peptidoglycan binding 1/1801 19/18639 0.0526315789473684 0.544697390338701 0.85510160508772 0.99999999998166 GO:0043395 heparan sulfate proteoglycan binding 1/1801 19/18639 0.0526315789473684 0.544697390338701 0.85510160508772 0.99999999998166 GO:0141147 intracellularly calcium-gated channel activity 1/1801 19/18639 0.0526315789473684 0.544697390338701 0.85510160508772 0.99999999998166 GO:0008188 neuropeptide receptor activity 3/1801 48/18639 0.0625 0.646828151027207 0.855362822029287 0.99999999998166 GO:0140789 histone phosphatase activity 10/1801 136/18639 0.0735294117647059 0.760974295326126 0.857352867012241 0.99999999998166 GO:0008509 monoatomic anion transmembrane transporter activity 11/1801 149/18639 0.0738255033557047 0.764038621347573 0.863159208577035 0.99999999998166 GO:0034061 DNA polymerase activity 2/1801 35/18639 0.0571428571428571 0.591385738082018 0.864887973085956 0.99999999998166 GO:0008083 growth factor activity 12/1801 162/18639 0.0740740740740741 0.766611141958171 0.868780801711808 0.99999999998166 GO:0001972 retinoic acid binding 1/1801 20/18639 0.05 0.517462520821766 0.869116750589171 0.99999999998166 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/1801 20/18639 0.05 0.517462520821766 0.869116750589171 0.99999999998166 GO:0030627 pre-mRNA 5'-splice site binding 1/1801 20/18639 0.05 0.517462520821766 0.869116750589171 0.99999999998166 GO:0140939 histone H4 methyltransferase activity 1/1801 20/18639 0.05 0.517462520821766 0.869116750589171 0.99999999998166 GO:0032813 tumor necrosis factor receptor superfamily binding 3/1801 50/18639 0.06 0.620955024986119 0.873799126818255 0.99999999998166 GO:0048020 CCR chemokine receptor binding 3/1801 50/18639 0.06 0.620955024986119 0.873799126818255 0.99999999998166 GO:0140101 catalytic activity, acting on a tRNA 10/1801 139/18639 0.0719424460431655 0.744550389671605 0.874458539823697 0.99999999998166 GO:0004190 aspartic-type endopeptidase activity 2/1801 36/18639 0.0555555555555556 0.574958356468629 0.875209093667715 0.99999999998166 GO:0003724 RNA helicase activity 5/1801 77/18639 0.0649350649350649 0.672029247820475 0.876840629138054 0.99999999998166 GO:0035402 histone H3T11 kinase activity 19/1801 247/18639 0.0769230769230769 0.79609618587964 0.880218334286912 0.99999999998166 GO:0010314 phosphatidylinositol-5-phosphate binding 1/1801 21/18639 0.0476190476190476 0.492821448401682 0.881776975745673 0.99999999998166 GO:0035613 RNA stem-loop binding 1/1801 21/18639 0.0476190476190476 0.492821448401682 0.881776975745673 0.99999999998166 GO:0051010 microtubule plus-end binding 1/1801 21/18639 0.0476190476190476 0.492821448401682 0.881776975745673 0.99999999998166 GO:0061891 calcium ion sensor activity 1/1801 21/18639 0.0476190476190476 0.492821448401682 0.881776975745673 0.99999999998166 GO:0019213 deacetylase activity 2/1801 37/18639 0.0540540540540541 0.559418941428936 0.884798483964537 0.99999999998166 GO:0070001 aspartic-type peptidase activity 2/1801 37/18639 0.0540540540540541 0.559418941428936 0.884798483964537 0.99999999998166 GO:0160215 deacylase activity 4/1801 65/18639 0.0615384615384615 0.636876948703712 0.885119078751534 0.99999999998166 GO:0008186 ATP-dependent activity, acting on RNA 5/1801 79/18639 0.0632911392405063 0.655015849141476 0.8901901577825 0.99999999998166 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 9/1801 130/18639 0.0692307692307692 0.716486567291676 0.891451891160154 0.99999999998166 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 12/1801 167/18639 0.0718562874251497 0.743658712558226 0.892813367026425 0.99999999998166 GO:0004407 histone deacetylase activity 1/1801 22/18639 0.0454545454545455 0.470420473474332 0.893213202337253 0.99999999998166 GO:0005243 gap junction channel activity 1/1801 22/18639 0.0454545454545455 0.470420473474332 0.893213202337253 0.99999999998166 GO:0015377 chloride:monoatomic cation symporter activity 1/1801 22/18639 0.0454545454545455 0.470420473474332 0.893213202337253 0.99999999998166 GO:0033558 protein lysine deacetylase activity 1/1801 22/18639 0.0454545454545455 0.470420473474332 0.893213202337253 0.99999999998166 GO:0033691 sialic acid binding 1/1801 22/18639 0.0454545454545455 0.470420473474332 0.893213202337253 0.99999999998166 GO:0042887 amide transmembrane transporter activity 2/1801 38/18639 0.0526315789473684 0.544697390338701 0.8937010951396 0.99999999998166 GO:0008168 methyltransferase activity 15/1801 204/18639 0.0735294117647059 0.760974295326126 0.896713063519984 0.99999999998166 GO:0008013 beta-catenin binding 7/1801 106/18639 0.0660377358490566 0.683441065236294 0.897069656741943 0.99999999998166 GO:0034212 protein N-acetyltransferase activity 3/1801 53/18639 0.0566037735849057 0.585806627345395 0.897551963966024 0.99999999998166 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/1801 67/18639 0.0597014925373134 0.617865696503601 0.898715168814918 0.99999999998166 GO:0042054 histone methyltransferase activity 4/1801 67/18639 0.0597014925373134 0.617865696503601 0.898715168814918 0.99999999998166 GO:0016410 N-acyltransferase activity 6/1801 94/18639 0.0638297872340425 0.660590452112892 0.901621880532848 0.99999999998166 GO:0042562 hormone binding 6/1801 94/18639 0.0638297872340425 0.660590452112892 0.901621880532848 0.99999999998166 GO:0003887 DNA-directed DNA polymerase activity 1/1801 23/18639 0.0434782608695652 0.449967409410231 0.903543707928412 0.99999999998166 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/1801 23/18639 0.0434782608695652 0.449967409410231 0.903543707928412 0.99999999998166 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/1801 23/18639 0.0434782608695652 0.449967409410231 0.903543707928412 0.99999999998166 GO:0005283 amino acid:sodium symporter activity 1/1801 23/18639 0.0434782608695652 0.449967409410231 0.903543707928412 0.99999999998166 GO:0043274 phospholipase binding 1/1801 23/18639 0.0434782608695652 0.449967409410231 0.903543707928412 0.99999999998166 GO:0070577 lysine-acetylated histone binding 1/1801 23/18639 0.0434782608695652 0.449967409410231 0.903543707928412 0.99999999998166 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/1801 23/18639 0.0434782608695652 0.449967409410231 0.903543707928412 0.99999999998166 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 18/1801 243/18639 0.0740740740740741 0.766611141958171 0.908498548952354 0.99999999998166 GO:0015144 carbohydrate transmembrane transporter activity 2/1801 40/18639 0.05 0.517462520821766 0.90961647352251 0.99999999998166 GO:0008080 N-acetyltransferase activity 4/1801 69/18639 0.0579710144927536 0.599956545880308 0.910872118219938 0.99999999998166 GO:0008374 O-acyltransferase activity 3/1801 55/18639 0.0545454545454545 0.564504568169199 0.911068663751544 0.99999999998166 GO:0016407 acetyltransferase activity 6/1801 96/18639 0.0625 0.646828151027207 0.911913604731359 0.99999999998166 GO:0030552 cAMP binding 1/1801 24/18639 0.0416666666666667 0.431218767351471 0.912875346412562 0.99999999998166 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/1801 24/18639 0.0416666666666667 0.431218767351471 0.912875346412562 0.99999999998166 GO:0140033 acetylation-dependent protein binding 1/1801 24/18639 0.0416666666666667 0.431218767351471 0.912875346412562 0.99999999998166 GO:0004676 3-phosphoinositide-dependent protein kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:0004711 ribosomal protein S6 kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:0035175 histone H3S10 kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:0035979 histone H2AXS139 kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:0044022 histone H3S28 kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:0044023 histone H4S1 kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:0044024 histone H2AS1 kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:0044025 histone H2BS14 kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:0072354 histone H3T3 kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:0072371 histone H2AS121 kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:0072518 Rho-dependent protein serine/threonine kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:0140823 histone H2BS36 kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:0140855 histone H3S57 kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:0140995 histone H2A kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:0140997 histone H4 kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:0140998 histone H2B kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:1990244 histone H2AT120 kinase activity 18/1801 245/18639 0.073469387755102 0.760353091819737 0.914894984030869 0.99999999998166 GO:0170055 lipid transmembrane transporter activity 3/1801 56/18639 0.0535714285714286 0.554424129451892 0.917200825426479 0.99999999998166 GO:0004677 DNA-dependent protein kinase activity 18/1801 246/18639 0.0731707317073171 0.757262225592828 0.917952395466579 0.99999999998166 GO:0140857 histone H3T45 kinase activity 18/1801 246/18639 0.0731707317073171 0.757262225592828 0.917952395466579 0.99999999998166 GO:0035403 histone H3T6 kinase activity 18/1801 247/18639 0.0728744939271255 0.754196386622816 0.920918391541836 0.99999999998166 GO:0004725 protein tyrosine phosphatase activity 6/1801 98/18639 0.0612244897959184 0.633627576516448 0.921257381504914 0.99999999998166 GO:0008170 N-methyltransferase activity 6/1801 98/18639 0.0612244897959184 0.633627576516448 0.921257381504914 0.99999999998166 GO:0003707 nuclear steroid receptor activity 1/1801 25/18639 0.04 0.413970016657413 0.921304650796713 0.99999999998166 GO:0005251 delayed rectifier potassium channel activity 1/1801 25/18639 0.04 0.413970016657413 0.921304650796713 0.99999999998166 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/1801 25/18639 0.04 0.413970016657413 0.921304650796713 0.99999999998166 GO:0017056 structural constituent of nuclear pore 1/1801 25/18639 0.04 0.413970016657413 0.921304650796713 0.99999999998166 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/1801 25/18639 0.04 0.413970016657413 0.921304650796713 0.99999999998166 GO:0031267 small GTPase binding 21/1801 283/18639 0.0742049469964664 0.767965578604741 0.921747721999511 0.99999999998166 GO:0004402 histone acetyltransferase activity 2/1801 42/18639 0.0476190476190476 0.492821448401682 0.923276920061629 0.99999999998166 GO:0043175 RNA polymerase core enzyme binding 2/1801 42/18639 0.0476190476190476 0.492821448401682 0.923276920061629 0.99999999998166 GO:0004679 AMP-activated protein kinase activity 18/1801 248/18639 0.0725806451612903 0.751155272160628 0.923794824233991 0.99999999998166 GO:0046943 carboxylic acid transmembrane transporter activity 13/1801 188/18639 0.0691489361702128 0.715639656455633 0.925814688241927 0.99999999998166 GO:0042379 chemokine receptor binding 4/1801 72/18639 0.0555555555555556 0.574958356468629 0.926675986976401 0.99999999998166 GO:0016791 phosphatase activity 20/1801 273/18639 0.0732600732600733 0.758186843694895 0.926777724674052 0.99999999998166 GO:0000510 H3-H4 histone complex chaperone activity 10/1801 151/18639 0.0662251655629139 0.685380822280484 0.926985497911249 0.99999999998166 GO:0140584 chromatin extrusion motor activity 10/1801 151/18639 0.0662251655629139 0.685380822280484 0.926985497911249 0.99999999998166 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 10/1801 151/18639 0.0662251655629139 0.685380822280484 0.926985497911249 0.99999999998166 GO:0140849 ATP-dependent H2AZ histone chaperone activity 10/1801 151/18639 0.0662251655629139 0.685380822280484 0.926985497911249 0.99999999998166 GO:0005342 organic acid transmembrane transporter activity 13/1801 189/18639 0.0687830687830688 0.711853203246873 0.928910183935125 0.99999999998166 GO:0008066 glutamate receptor activity 1/1801 26/18639 0.0384615384615385 0.39804809293982 0.928918829582311 0.99999999998166 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/1801 26/18639 0.0384615384615385 0.39804809293982 0.928918829582311 0.99999999998166 GO:0008143 poly(A) binding 1/1801 26/18639 0.0384615384615385 0.39804809293982 0.928918829582311 0.99999999998166 GO:0019865 immunoglobulin binding 1/1801 26/18639 0.0384615384615385 0.39804809293982 0.928918829582311 0.99999999998166 GO:0030247 polysaccharide binding 1/1801 26/18639 0.0384615384615385 0.39804809293982 0.928918829582311 0.99999999998166 GO:0051139 metal cation:proton antiporter activity 1/1801 26/18639 0.0384615384615385 0.39804809293982 0.928918829582311 0.99999999998166 GO:0052742 phosphatidylinositol kinase activity 1/1801 26/18639 0.0384615384615385 0.39804809293982 0.928918829582311 0.99999999998166 GO:0015616 DNA translocase activity 10/1801 152/18639 0.0657894736842105 0.680871737923376 0.930358047292152 0.99999999998166 GO:0140674 ATP-dependent histone chaperone activity 10/1801 152/18639 0.0657894736842105 0.680871737923376 0.930358047292152 0.99999999998166 GO:0070888 E-box binding 3/1801 59/18639 0.0508474576271186 0.526233072022135 0.933351681747991 0.99999999998166 GO:0061775 cohesin loader activity 10/1801 153/18639 0.065359477124183 0.676421595845445 0.933595562839255 0.99999999998166 GO:0005044 scavenger receptor activity 1/1801 27/18639 0.037037037037037 0.383305570979086 0.93579666700359 0.99999999998166 GO:0008395 steroid hydroxylase activity 1/1801 27/18639 0.037037037037037 0.383305570979086 0.93579666700359 0.99999999998166 GO:0015252 proton channel activity 1/1801 27/18639 0.037037037037037 0.383305570979086 0.93579666700359 0.99999999998166 GO:0035255 ionotropic glutamate receptor binding 1/1801 27/18639 0.037037037037037 0.383305570979086 0.93579666700359 0.99999999998166 GO:0001221 transcription coregulator binding 7/1801 115/18639 0.0608695652173913 0.629954373174323 0.93617674707077 0.99999999998166 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 5/1801 89/18639 0.0561797752808989 0.581418562721085 0.939742979355428 0.99999999998166 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 5/1801 89/18639 0.0561797752808989 0.581418562721085 0.939742979355428 0.99999999998166 GO:0005085 guanyl-nucleotide exchange factor activity 16/1801 230/18639 0.0695652173913043 0.71994785505637 0.940127801046589 0.99999999998166 GO:0042578 phosphoric ester hydrolase activity 27/1801 363/18639 0.0743801652892562 0.769778956594362 0.942413563920878 0.99999999998166 GO:0140793 histone H2AXY142 phosphatase activity 5/1801 90/18639 0.0555555555555556 0.574958356468629 0.943379836325124 0.99999999998166 GO:0030276 clathrin binding 2/1801 46/18639 0.0434782608695652 0.449967409410231 0.944964811602473 0.99999999998166 GO:0015179 L-amino acid transmembrane transporter activity 3/1801 62/18639 0.0483870967741935 0.500770181440418 0.94655168282891 0.99999999998166 GO:0005416 amino acid:monoatomic cation symporter activity 1/1801 29/18639 0.0344827586206897 0.356870704015011 0.947621135071315 0.99999999998166 GO:0061733 protein-lysine-acetyltransferase activity 2/1801 47/18639 0.0425531914893617 0.440393634741928 0.94939483150747 0.99999999998166 GO:0140938 histone H3 methyltransferase activity 2/1801 47/18639 0.0425531914893617 0.440393634741928 0.94939483150747 0.99999999998166 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/1801 30/18639 0.0333333333333333 0.344975013881177 0.952690148275859 0.99999999998166 GO:0033612 receptor serine/threonine kinase binding 1/1801 30/18639 0.0333333333333333 0.344975013881177 0.952690148275859 0.99999999998166 GO:0070566 adenylyltransferase activity 1/1801 30/18639 0.0333333333333333 0.344975013881177 0.952690148275859 0.99999999998166 GO:0003689 DNA clamp loader activity 10/1801 160/18639 0.0625 0.646828151027207 0.952816461812956 0.99999999998166 GO:0140030 modification-dependent protein binding 11/1801 173/18639 0.0635838150289017 0.658044824166407 0.953078194310698 0.99999999998166 GO:0140693 molecular condensate scaffold activity 2/1801 48/18639 0.0416666666666667 0.431218767351471 0.953483179745651 0.99999999998166 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 7/1801 122/18639 0.0573770491803279 0.593809450123338 0.956867059223296 0.99999999998166 GO:0035254 glutamate receptor binding 2/1801 49/18639 0.0408163265306122 0.422418384344298 0.957254478479248 0.99999999998166 GO:0070717 poly-purine tract binding 1/1801 32/18639 0.03125 0.323414075513604 0.961404640273452 0.99999999998166 GO:0016597 amino acid binding 2/1801 51/18639 0.0392156862745098 0.405852957507267 0.963936663100388 0.99999999998166 GO:0017046 peptide hormone binding 2/1801 53/18639 0.0377358490566038 0.390537751563597 0.969608367673576 0.99999999998166 GO:0140375 immune receptor activity 9/1801 156/18639 0.0576923076923077 0.59707213940973 0.970779324620164 0.99999999998166 GO:0005343 organic acid:sodium symporter activity 1/1801 35/18639 0.0285714285714286 0.295692869041009 0.971562488254317 0.99999999998166 GO:0106310 protein serine kinase activity 25/1801 361/18639 0.0692520775623269 0.716707092550922 0.973579129243075 0.99999999998166 GO:0003730 mRNA 3'-UTR binding 17/1801 262/18639 0.0648854961832061 0.671516248394658 0.973756235514886 0.99999999998166 GO:0000993 RNA polymerase II complex binding 1/1801 36/18639 0.0277777777777778 0.287479178234314 0.974315442385363 0.99999999998166 GO:0045505 dynein intermediate chain binding 1/1801 36/18639 0.0277777777777778 0.287479178234314 0.974315442385363 0.99999999998166 GO:0005262 calcium channel activity 7/1801 131/18639 0.0534351145038168 0.553013381030895 0.974533833336246 0.99999999998166 GO:0030280 structural constituent of skin epidermis 1/1801 37/18639 0.027027027027027 0.279709470714468 0.976802024563719 0.99999999998166 GO:0140767 enzyme-substrate adaptor activity 7/1801 139/18639 0.0503597122302158 0.521185272770124 0.984369792866261 0.99999999998166 GO:0001727 lipid kinase activity 1/1801 41/18639 0.024390243902439 0.252420741864276 0.984563919550257 0.99999999998166 GO:0004812 aminoacyl-tRNA ligase activity 1/1801 41/18639 0.024390243902439 0.252420741864276 0.984563919550257 0.99999999998166 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/1801 41/18639 0.024390243902439 0.252420741864276 0.984563919550257 0.99999999998166 GO:0005245 voltage-gated calcium channel activity 1/1801 43/18639 0.0232558139534884 0.240680242242682 0.987408847410245 0.99999999998166 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 16/1801 268/18639 0.0597014925373134 0.617865696503601 0.989017858379439 0.99999999998166 GO:0005254 chloride channel activity 3/1801 83/18639 0.036144578313253 0.374069292160313 0.989514449769419 0.99999999998166 GO:0008009 chemokine activity 1/1801 45/18639 0.0222222222222222 0.229983342587451 0.989729681218563 0.99999999998166 GO:0099095 ligand-gated monoatomic anion channel activity 1/1801 47/18639 0.0212765957446809 0.220196817370964 0.991622926198734 0.99999999998166 GO:0032266 phosphatidylinositol-3-phosphate binding 1/1801 48/18639 0.0208333333333333 0.215609383675736 0.992434410165821 0.99999999998166 GO:0016279 protein-lysine N-methyltransferase activity 2/1801 69/18639 0.0289855072463768 0.299978272940154 0.992521247227724 0.99999999998166 GO:0015108 chloride transmembrane transporter activity 5/1801 121/18639 0.0413223140495868 0.427654975885757 0.992996636640568 0.99999999998166 GO:0016278 lysine N-methyltransferase activity 2/1801 70/18639 0.0285714285714286 0.295692869041009 0.99315997141401 0.99999999998166 GO:0001222 transcription corepressor binding 1/1801 49/18639 0.0204081632653061 0.211209192172149 0.993167325409292 0.99999999998166 GO:0001217 DNA-binding transcription repressor activity 16/1801 278/18639 0.0575539568345324 0.595640311737284 0.993301018063146 0.99999999998166 GO:0008528 G protein-coupled peptide receptor activity 5/1801 122/18639 0.040983606557377 0.424149607230955 0.993481580828507 0.99999999998166 GO:0004497 monooxygenase activity 4/1801 106/18639 0.0377358490566038 0.390537751563597 0.993557588549952 0.99999999998166 GO:0035064 methylated histone binding 2/1801 74/18639 0.027027027027027 0.279709470714468 0.995221684677516 0.99999999998166 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/1801 53/18639 0.0188679245283019 0.195268875781798 0.995454753336796 0.99999999998166 GO:0003823 antigen binding 8/1801 174/18639 0.0459770114942529 0.475827605353348 0.995689250050335 0.99999999998166 GO:0001653 peptide receptor activity 5/1801 128/18639 0.0390625 0.404267594392004 0.995781908237307 0.99999999998166 GO:0140034 methylation-dependent protein binding 2/1801 76/18639 0.0263157894736842 0.27234869516935 0.996009872134851 0.99999999998166 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/1801 56/18639 0.0178571428571429 0.184808043150631 0.996652225688033 0.99999999998166 GO:0015370 solute:sodium symporter activity 2/1801 79/18639 0.0253164556962025 0.26200633965659 0.996958469462293 0.99999999998166 GO:0015103 inorganic anion transmembrane transporter activity 7/1801 165/18639 0.0424242424242424 0.439059108576044 0.997130292990947 0.99999999998166 GO:0022824 transmitter-gated monoatomic ion channel activity 1/1801 63/18639 0.0158730158730159 0.164273816133894 0.998360170407823 0.99999999998166 GO:0022835 transmitter-gated channel activity 1/1801 63/18639 0.0158730158730159 0.164273816133894 0.998360170407823 0.99999999998166 GO:0019787 ubiquitin-like protein transferase activity 29/1801 479/18639 0.0605427974947808 0.626572572185019 0.998424362860214 0.99999999998166 GO:0004842 ubiquitin-protein transferase activity 26/1801 449/18639 0.0579064587973274 0.599288442822535 0.998973686366343 0.99999999998166 GO:0098960 postsynaptic neurotransmitter receptor activity 1/1801 69/18639 0.0144927536231884 0.149989136470077 0.999110751749579 0.99999999998166 GO:0016755 aminoacyltransferase activity 29/1801 496/18639 0.0584677419354839 0.605097302573839 0.999280209822891 0.99999999998166 GO:0005125 cytokine activity 10/1801 234/18639 0.0427350427350427 0.442275658822022 0.999378119081123 0.99999999998166 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/1801 73/18639 0.0136986301369863 0.141770553649799 0.999408725716132 0.99999999998166 GO:0030594 neurotransmitter receptor activity 2/1801 97/18639 0.0206185567010309 0.213386606524439 0.999416873241763 0.99999999998166 GO:0030695 GTPase regulator activity 28/1801 489/18639 0.0572597137014315 0.592595115869507 0.999464522125426 0.99999999998166 GO:0005244 voltage-gated monoatomic ion channel activity 6/1801 173/18639 0.0346820809248555 0.358933540454404 0.999489423734592 0.99999999998166 GO:0060589 nucleoside-triphosphatase regulator activity 28/1801 490/18639 0.0571428571428571 0.591385738082018 0.999489807939066 0.99999999998166 GO:0001216 DNA-binding transcription activator activity 28/1801 491/18639 0.0570264765784114 0.590181286476963 0.999513954047734 0.99999999998166 GO:0022832 voltage-gated channel activity 6/1801 175/18639 0.0342857142857143 0.354831442849211 0.999560654070716 0.99999999998166 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 27/1801 484/18639 0.0557851239669422 0.577334217445772 0.99964443037878 0.99999999998166 GO:0061630 ubiquitin protein ligase activity 17/1801 353/18639 0.0481586402266289 0.498405827420398 0.999762457756534 0.99999999998166 GO:0061659 ubiquitin-like protein ligase activity 18/1801 372/18639 0.0483870967741935 0.500770181440418 0.999818636703089 0.99999999998166 GO:0005096 GTPase activator activity 11/1801 271/18639 0.040590405904059 0.420080275205861 0.99985101958754 0.99999999998166 GO:0046873 metal ion transmembrane transporter activity 23/1801 450/18639 0.0511111111111111 0.528961687951138 0.999879649571313 0.99999999998166 GO:0022843 voltage-gated monoatomic cation channel activity 3/1801 143/18639 0.020979020979021 0.217117141603538 0.999938003378201 0.99999999998166 GO:0015081 sodium ion transmembrane transporter activity 4/1801 164/18639 0.024390243902439 0.252420741864276 0.999942039150421 0.99999999998166 GO:0005249 voltage-gated potassium channel activity 1/1801 98/18639 0.0102040816326531 0.105604596086075 0.999953956883612 0.99999999998166 GO:0030527 structural constituent of chromatin 1/1801 98/18639 0.0102040816326531 0.105604596086075 0.999953956883612 0.99999999998166 GO:0005216 monoatomic ion channel activity 21/1801 448/18639 0.046875 0.485121113270405 0.999973275277809 0.99999999998166 GO:0099094 ligand-gated monoatomic cation channel activity 2/1801 136/18639 0.0147058823529412 0.152194859065225 0.99998521075569 0.99999999998166 GO:0015276 ligand-gated monoatomic ion channel activity 4/1801 186/18639 0.021505376344086 0.22256452508463 0.999991293271794 0.99999999998166 GO:0022834 ligand-gated channel activity 4/1801 188/18639 0.0212765957446809 0.220196817370964 0.999992687328538 0.99999999998166 GO:0022836 gated channel activity 11/1801 318/18639 0.0345911949685535 0.357992938933297 0.999994366574601 0.99999999998166 GO:0005267 potassium channel activity 1/1801 124/18639 0.00806451612903226 0.0834616969067364 0.999996775037304 0.99999999998166 GO:0015079 potassium ion transmembrane transporter activity 2/1801 160/18639 0.0125 0.129365630205441 0.99999852473084 0.99999999998166 GO:0045182 translation regulator activity 11/1801 356/18639 0.0308988764044944 0.319780209496597 0.999999661183484 0.99999999998166 GO:0005261 monoatomic cation channel activity 10/1801 341/18639 0.0293255131964809 0.30349707966086 0.99999972087592 0.99999999998166 GO:0030371 translation repressor activity 4/1801 329/18639 0.0121580547112462 0.125826752783408 0.99999999998166 0.99999999998166