ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 97/1486 175/18639 0.554285714285714 6.95244376081523 3.73003130050247e-60 4.25969574517382e-57 GO:0045296 cadherin binding 83/1486 334/18639 0.248502994011976 3.11699011129826 2.65012512018499e-21 1.51322144362563e-18 GO:0048027 mRNA 5'-UTR binding 14/1486 24/18639 0.583333333333333 7.31679004037685 3.61433137444343e-10 1.37585547653813e-07 GO:0016853 isomerase activity 40/1486 180/18639 0.222222222222222 2.78734858681023 2.09294941859221e-09 5.97537059008077e-07 GO:0005201 extracellular matrix structural constituent 38/1486 168/18639 0.226190476190476 2.83712266871755 3.11612577329444e-09 7.11723126620451e-07 GO:0016860 intramolecular oxidoreductase activity 19/1486 53/18639 0.358490566037736 4.49657177683537 1.03366539938946e-08 1.96740981017126e-06 GO:0019843 rRNA binding 21/1486 65/18639 0.323076923076923 4.05237602236256 1.4879047038145e-08 2.15497209074803e-06 GO:0051082 unfolded protein binding 30/1486 121/18639 0.247933884297521 3.10985172908579 1.5096126730284e-08 2.15497209074803e-06 GO:0019838 growth factor binding 32/1486 136/18639 0.235294117647059 2.9513102683873 1.97328946771843e-08 2.50388508014938e-06 GO:0003743 translation initiation factor activity 18/1486 51/18639 0.352941176470588 4.42696540258095 3.34283105397694e-08 3.81751306364166e-06 GO:0043021 ribonucleoprotein complex binding 37/1486 177/18639 0.209039548022599 2.62199739945708 4.62992067725566e-08 4.80669946675088e-06 GO:0003697 single-stranded DNA binding 29/1486 121/18639 0.239669421487603 3.00619000478293 5.84974661820077e-08 5.47865757810616e-06 GO:0031720 haptoglobin binding 8/1486 10/18639 0.8 10.0344549125168 6.23665048295797e-08 5.47865757810616e-06 GO:0008135 translation factor activity, RNA binding 23/1486 83/18639 0.27710843373494 3.47579010523926 7.91143865378244e-08 6.45347353044254e-06 GO:0180051 translation factor activity 23/1486 84/18639 0.273809523809524 3.43441165160546 1.00799088916756e-07 7.67417063619567e-06 GO:0015035 protein-disulfide reductase activity 14/1486 34/18639 0.411764705882353 5.16479296967778 1.19670870563324e-07 8.54150838645729e-06 GO:0048407 platelet-derived growth factor binding 8/1486 11/18639 0.727272727272727 9.12223173865166 2.12581082577278e-07 1.3487088683514e-05 GO:1990948 ubiquitin ligase inhibitor activity 8/1486 11/18639 0.727272727272727 9.12223173865166 2.12581082577278e-07 1.3487088683514e-05 GO:0055105 ubiquitin-protein transferase inhibitor activity 9/1486 15/18639 0.6 7.52584118438762 4.08829870790435e-07 2.45728269706672e-05 GO:0003756 protein disulfide isomerase activity 10/1486 19/18639 0.526315789473684 6.60161507402423 4.76384333786871e-07 2.59062337706956e-05 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 10/1486 19/18639 0.526315789473684 6.60161507402423 4.76384333786871e-07 2.59062337706956e-05 GO:0016887 ATP hydrolysis activity 63/1486 417/18639 0.151079136690647 1.89499598168034 6.13277824610784e-07 3.18346943502507e-05 GO:0030020 extracellular matrix structural constituent conferring tensile strength 15/1486 44/18639 0.340909090909091 4.27604612749296 7.80390653522827e-07 3.8748092448829e-05 GO:0003678 DNA helicase activity 20/1486 74/18639 0.27027027027027 3.39001855152595 8.52377970227659e-07 4.05589850833328e-05 GO:0004601 peroxidase activity 17/1486 57/18639 0.298245614035088 3.74091520861373 1.24911639329805e-06 5.34815974200192e-05 GO:0015036 disulfide oxidoreductase activity 14/1486 40/18639 0.35 4.39007402422611 1.26445107735597e-06 5.34815974200192e-05 GO:0140662 ATP-dependent protein folding chaperone 14/1486 40/18639 0.35 4.39007402422611 1.26445107735597e-06 5.34815974200192e-05 GO:0017116 single-stranded DNA helicase activity 17/1486 58/18639 0.293103448275862 3.67641667053418 1.63666792465227e-06 6.67526703554603e-05 GO:0043022 ribosome binding 25/1486 112/18639 0.223214285714286 2.79979210728706 1.93737631401668e-06 7.62925431243809e-05 GO:0055106 ubiquitin-protein transferase regulator activity 13/1486 36/18639 0.361111111111111 4.52944145356662 2.01824303395797e-06 7.68277848260002e-05 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 17/1486 59/18639 0.288135593220339 3.61410452357597 2.12954639582856e-06 7.84497414205229e-05 GO:0003779 actin binding 64/1486 443/18639 0.144469525959368 1.81209118058995 2.3919677881932e-06 8.53633504411449e-05 GO:0005344 oxygen carrier activity 8/1486 14/18639 0.571428571428571 7.16746779465487 3.10946362243669e-06 0.000107606286570385 GO:0044183 protein folding chaperone 19/1486 75/18639 0.253333333333333 3.17757738896366 4.56644234572837e-06 0.000153378739965347 GO:0005518 collagen binding 18/1486 72/18639 0.25 3.13576716016151 9.87890510820543e-06 0.000314611338595907 GO:0005178 integrin binding 30/1486 161/18639 0.186335403726708 2.33721775912659 9.9176954373491e-06 0.000314611338595907 GO:0004857 enzyme inhibitor activity 59/1486 416/18639 0.141826923076923 1.77894483124547 1.04228674452705e-05 0.000321700395202673 GO:0003688 DNA replication origin binding 8/1486 16/18639 0.5 6.27153432032302 1.15237126598629e-05 0.000346317890988513 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 15/1486 54/18639 0.277777777777778 3.48418573351279 1.37248560920687e-05 0.000401891939926731 GO:0031625 ubiquitin protein ligase binding 46/1486 302/18639 0.152317880794702 1.91053363400569 1.58080541062617e-05 0.000451319944733772 GO:0044389 ubiquitin-like protein ligase binding 48/1486 322/18639 0.149068322981366 1.86977420730127 1.86208814098487e-05 0.000518659672440176 GO:0140097 catalytic activity, acting on DNA 49/1486 336/18639 0.145833333333333 1.82919751009421 2.75505998808752e-05 0.000749113930094274 GO:0019825 oxygen binding 11/1486 34/18639 0.323529411764706 4.05805161903254 4.08516571248954e-05 0.0010849440101542 GO:0051015 actin filament binding 34/1486 209/18639 0.162679425837321 2.0404992046984 5.1571030288212e-05 0.00133850264975314 GO:0048029 monosaccharide binding 17/1486 74/18639 0.22972972972973 2.88151576879706 5.59645178056084e-05 0.00141294938039772 GO:0008094 ATP-dependent activity, acting on DNA 34/1486 210/18639 0.161904761904762 2.03078254181888 5.69138979844967e-05 0.00141294938039772 GO:0140104 molecular carrier activity 38/1486 249/18639 0.152610441767068 1.91420324636365 8.02830073420845e-05 0.00195070626350342 GO:0005539 glycosaminoglycan binding 37/1486 242/18639 0.152892561983471 1.9177418996029 9.52327119747782e-05 0.0022657449390666 GO:0016209 antioxidant activity 18/1486 86/18639 0.209302325581395 2.62529343641429 0.000124709671951912 0.00290386583665344 GO:0030515 snoRNA binding 10/1486 32/18639 0.3125 3.91970895020188 0.000127139484967314 0.00290386583665344 GO:0000217 DNA secondary structure binding 11/1486 39/18639 0.282051282051282 3.53778859095144 0.000165117408996143 0.00369733492301167 GO:0003727 single-stranded RNA binding 18/1486 89/18639 0.202247191011236 2.53680039923178 0.000197122655857723 0.00432911678825999 GO:0061749 forked DNA-dependent helicase activity 12/1486 47/18639 0.25531914893617 3.20248561037771 0.000237781917347042 0.00502864721500597 GO:1990518 single-stranded 3'-5' DNA helicase activity 12/1486 47/18639 0.25531914893617 3.20248561037771 0.000237781917347042 0.00502864721500597 GO:0017134 fibroblast growth factor binding 8/1486 23/18639 0.347826086956522 4.36280648370297 0.00026462131596578 0.00534213831896293 GO:0016829 lyase activity 31/1486 200/18639 0.155 1.94417563930013 0.000264884407105402 0.00534213831896293 GO:0031994 insulin-like growth factor I binding 6/1486 13/18639 0.461538461538462 5.78910860337509 0.000267119059658688 0.00534213831896293 GO:0098631 cell adhesion mediator activity 16/1486 76/18639 0.210526315789474 2.64064602960969 0.000271317007442951 0.00534213831896293 GO:0043236 laminin binding 9/1486 29/18639 0.310344827586207 3.89267647468325 0.000293293996130096 0.0054207614685262 GO:0009378 four-way junction helicase activity 12/1486 48/18639 0.25 3.13576716016151 0.000294297032441878 0.0054207614685262 GO:0036121 double-stranded DNA helicase activity 12/1486 48/18639 0.25 3.13576716016151 0.000294297032441878 0.0054207614685262 GO:0043138 3'-5' DNA helicase activity 12/1486 48/18639 0.25 3.13576716016151 0.000294297032441878 0.0054207614685262 GO:0019842 vitamin binding 25/1486 150/18639 0.166666666666667 2.09051144010767 0.000330980547534713 0.00599967913150227 GO:0097110 scaffold protein binding 15/1486 70/18639 0.214285714285714 2.68780042299558 0.000340882395179022 0.00608262023897568 GO:0001968 fibronectin binding 9/1486 30/18639 0.3 3.76292059219381 0.000389585458249142 0.00674100898970486 GO:0008187 poly-pyrimidine tract binding 9/1486 30/18639 0.3 3.76292059219381 0.000389585458249142 0.00674100898970486 GO:0015631 tubulin binding 50/1486 385/18639 0.12987012987013 1.62896995333065 0.000423654388397287 0.00722109420223436 GO:0005520 insulin-like growth factor binding 7/1486 19/18639 0.368421052631579 4.62113055181696 0.0004317430168694 0.0072507430186008 GO:0004386 helicase activity 25/1486 155/18639 0.161290322580645 2.02307558720097 0.000549385752096314 0.00909273230281145 GO:0005522 profilin binding 5/1486 10/18639 0.5 6.27153432032302 0.000573459927538645 0.00935558910355904 GO:0043024 ribosomal small subunit binding 7/1486 20/18639 0.35 4.39007402422611 0.000618763565044938 0.00995250691945521 GO:0008017 microtubule binding 38/1486 276/18639 0.13768115942029 1.72694423313242 0.000662046417755859 0.0105007917927388 GO:0050840 extracellular matrix binding 14/1486 67/18639 0.208955223880597 2.62093971595589 0.00069529614292375 0.0108770985646428 GO:0008266 poly(U) RNA binding 8/1486 27/18639 0.296296296296296 3.71646478241364 0.000898777523323258 0.0137363471774772 GO:0051087 protein-folding chaperone binding 22/1486 134/18639 0.164179104477612 2.05930977682248 0.000902124376804546 0.0137363471774772 GO:0005536 D-glucose binding 5/1486 11/18639 0.454545454545455 5.70139483665729 0.000982420633335994 0.0145704462762299 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 5/1486 11/18639 0.454545454545455 5.70139483665729 0.000982420633335994 0.0145704462762299 GO:0008142 oxysterol binding 6/1486 16/18639 0.375 4.70365074024226 0.0010116377094464 0.0148114136434331 GO:0019887 protein kinase regulator activity 35/1486 255/18639 0.137254901960784 1.72159765655926 0.0011172293086875 0.0161503274749509 GO:0140517 protein-RNA adaptor activity 7/1486 22/18639 0.318181818181818 3.9909763856601 0.0011816888530681 0.0167188940215903 GO:1901681 sulfur compound binding 37/1486 275/18639 0.134545454545455 1.68761287165056 0.00118584099452611 0.0167188940215903 GO:0005200 structural constituent of cytoskeleton 19/1486 112/18639 0.169642857142857 2.12784200153817 0.0013192965705384 0.0183736180921324 GO:0008307 structural constituent of muscle 10/1486 42/18639 0.238095238095238 2.98644491443953 0.00139307433654172 0.019167360148562 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 9/1486 36/18639 0.25 3.13576716016151 0.00165916433893077 0.0220321590123133 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 9/1486 36/18639 0.25 3.13576716016151 0.00165916433893077 0.0220321590123133 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 9/1486 36/18639 0.25 3.13576716016151 0.00165916433893077 0.0220321590123133 GO:0003684 damaged DNA binding 14/1486 74/18639 0.189189189189189 2.37301298606817 0.0019194453333212 0.0251954778235956 GO:0003689 DNA clamp loader activity 24/1486 160/18639 0.15 1.8814602960969 0.00196004445124463 0.0254360314013792 GO:0003713 transcription coactivator activity 34/1486 256/18639 0.1328125 1.6658763038358 0.00227587235281728 0.0292027665945767 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 5/1486 13/18639 0.384615384615385 4.82425716947924 0.00239076766736699 0.0303361852903678 GO:0051117 ATPase binding 15/1486 84/18639 0.178571428571429 2.23983368582965 0.00244414900322063 0.0306727270514062 GO:0008201 heparin binding 25/1486 172/18639 0.145348837209302 1.82312044195436 0.00248202382260585 0.0308094696240857 GO:0008301 DNA binding, bending 6/1486 19/18639 0.315789473684211 3.96096904441454 0.00278466369729409 0.0341944724979554 GO:0070717 poly-purine tract binding 8/1486 32/18639 0.25 3.13576716016151 0.0029784504250058 0.0361555542793229 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 9/1486 39/18639 0.230769230769231 2.89455430168755 0.00300768621412931 0.0361555542793229 GO:0008143 poly(A) binding 7/1486 26/18639 0.269230769230769 3.37698001863547 0.00343881642688405 0.0409075870781415 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 19/1486 122/18639 0.155737704918033 1.95342872272356 0.00361101552008305 0.0425131930302561 GO:0030170 pyridoxal phosphate binding 11/1486 56/18639 0.196428571428571 2.46381705441261 0.00419637055589201 0.0489005630084559 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 9/1486 41/18639 0.219512195121951 2.75335653087352 0.00430576959087695 0.0489344743490577 GO:0140318 protein transporter activity 9/1486 41/18639 0.219512195121951 2.75335653087352 0.00430576959087695 0.0489344743490577 GO:0008320 protein transmembrane transporter activity 7/1486 27/18639 0.259259259259259 3.25190668461193 0.00432783004313032 0.0489344743490577 GO:0019207 kinase regulator activity 36/1486 287/18639 0.125435540069686 1.57334658907058 0.00450917590193336 0.050485087058901 GO:0001618 virus receptor activity 14/1486 81/18639 0.172839506172839 2.16793778974129 0.00455704740382473 0.0505257100501732 GO:0043539 protein serine/threonine kinase activator activity 13/1486 73/18639 0.178082191780822 2.23369715518354 0.00473360732527804 0.0519786496679569 GO:0070279 vitamin B6 binding 11/1486 57/18639 0.192982456140351 2.42059219380888 0.00483343420139589 0.0520438233602579 GO:0070182 DNA polymerase binding 6/1486 21/18639 0.285714285714286 3.58373389732744 0.00485218407320437 0.0520438233602579 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 5/1486 15/18639 0.333333333333333 4.18102288021534 0.00487626015722207 0.0520438233602579 GO:0003774 cytoskeletal motor activity 22/1486 153/18639 0.143790849673203 1.8035784973478 0.00496535468245893 0.0525040282163713 GO:0016859 cis-trans isomerase activity 9/1486 42/18639 0.214285714285714 2.68780042299558 0.00510014102387746 0.0529669429158889 GO:0140272 exogenous protein binding 14/1486 82/18639 0.170731707317073 2.14149952401274 0.0051018946766618 0.0529669429158889 GO:0097718 disordered domain specific binding 7/1486 28/18639 0.25 3.13576716016151 0.00538001782201589 0.0553511743490284 GO:0044325 transmembrane transporter binding 20/1486 136/18639 0.147058823529412 1.84456891774206 0.00558307547366819 0.05625499626693 GO:0140713 histone chaperone activity 23/1486 164/18639 0.140243902439024 1.75908889472475 0.005635298013959 0.05625499626693 GO:0001094 TFIID-class transcription factor complex binding 4/1486 10/18639 0.4 5.01722745625841 0.00571416774690357 0.05625499626693 GO:0047429 nucleoside triphosphate diphosphatase activity 4/1486 10/18639 0.4 5.01722745625841 0.00571416774690357 0.05625499626693 GO:0050815 phosphoserine residue binding 4/1486 10/18639 0.4 5.01722745625841 0.00571416774690357 0.05625499626693 GO:0030021 extracellular matrix structural constituent conferring compression resistance 6/1486 22/18639 0.272727272727273 3.42083690199437 0.00622861978075548 0.060280371098498 GO:0070034 telomerase RNA binding 6/1486 22/18639 0.272727272727273 3.42083690199437 0.00622861978075548 0.060280371098498 GO:0070411 I-SMAD binding 5/1486 16/18639 0.3125 3.91970895020188 0.00663290672439281 0.0636536090693831 GO:0032934 sterol binding 12/1486 68/18639 0.176470588235294 2.21348270129048 0.00701687552933356 0.0667772654541578 GO:0140597 protein carrier chaperone 25/1486 188/18639 0.132978723404255 1.66796125540506 0.00794349578302353 0.0749708444976271 GO:0004523 RNA-DNA hybrid ribonuclease activity 4/1486 11/18639 0.363636363636364 4.56111586932583 0.00841802324037075 0.0769070603240271 GO:0034511 U3 snoRNA binding 4/1486 11/18639 0.363636363636364 4.56111586932583 0.00841802324037075 0.0769070603240271 GO:0050786 RAGE receptor binding 4/1486 11/18639 0.363636363636364 4.56111586932583 0.00841802324037075 0.0769070603240271 GO:0070990 snRNP binding 4/1486 11/18639 0.363636363636364 4.56111586932583 0.00841802324037075 0.0769070603240271 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 19/1486 132/18639 0.143939393939394 1.80544169827481 0.00853110541540512 0.0773216062253384 GO:0004550 nucleoside diphosphate kinase activity 5/1486 17/18639 0.294117647058824 3.68913783548413 0.00878883831110035 0.0784129168068484 GO:0051787 misfolded protein binding 5/1486 17/18639 0.294117647058824 3.68913783548413 0.00878883831110035 0.0784129168068484 GO:0046332 SMAD binding 13/1486 79/18639 0.164556962025316 2.06404926997973 0.00930258927912598 0.0823531547035804 GO:0005540 hyaluronic acid binding 6/1486 24/18639 0.25 3.13576716016151 0.00979684371301241 0.0860615040020013 GO:0098632 cell-cell adhesion mediator activity 10/1486 55/18639 0.181818181818182 2.28055793466291 0.0107848029905892 0.0940171375210144 GO:0000400 four-way junction DNA binding 5/1486 18/18639 0.277777777777778 3.48418573351279 0.0113839160792151 0.0970181504661468 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 5/1486 18/18639 0.277777777777778 3.48418573351279 0.0113839160792151 0.0970181504661468 GO:0098641 cadherin binding involved in cell-cell adhesion 5/1486 18/18639 0.277777777777778 3.48418573351279 0.0113839160792151 0.0970181504661468 GO:0022884 macromolecule transmembrane transporter activity 7/1486 32/18639 0.21875 2.74379626514132 0.0115690552122045 0.097394836010533 GO:0019210 kinase inhibitor activity 14/1486 90/18639 0.155555555555556 1.95114401076716 0.0115986844986274 0.097394836010533 GO:0031543 peptidyl-proline dioxygenase activity 4/1486 12/18639 0.333333333333333 4.18102288021534 0.0118400449898935 0.0979806621627416 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 4/1486 12/18639 0.333333333333333 4.18102288021534 0.0118400449898935 0.0979806621627416 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 9/1486 48/18639 0.1875 2.35182537012113 0.0124870380913523 0.102591348923197 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 18/1486 128/18639 0.140625 1.76386902759085 0.0129282888774957 0.105457899272144 GO:0140658 ATP-dependent chromatin remodeler activity 21/1486 158/18639 0.132911392405063 1.66711671806055 0.0142025726288968 0.115030765547519 GO:0008574 plus-end-directed microtubule motor activity 5/1486 19/18639 0.263157894736842 3.30080753701211 0.0144550776441869 0.116251399082123 GO:0004860 protein kinase inhibitor activity 13/1486 84/18639 0.154761904761905 1.9411891943857 0.0152780461466861 0.122010690206402 GO:0019104 DNA N-glycosylase activity 4/1486 13/18639 0.307692307692308 3.85940573558339 0.0160397237999052 0.126326652272357 GO:0140666 annealing activity 4/1486 13/18639 0.307692307692308 3.85940573558339 0.0160397237999052 0.126326652272357 GO:0005007 fibroblast growth factor receptor activity 9/1486 50/18639 0.18 2.25775235531629 0.0161783597326127 0.1265458001003 GO:0000287 magnesium ion binding 28/1486 230/18639 0.121739130434783 1.52698226929604 0.0163732342203936 0.127198867208772 GO:0000510 H3-H4 histone complex chaperone activity 20/1486 151/18639 0.132450331125828 1.66133359478755 0.0170071132538226 0.128017246042187 GO:0140584 chromatin extrusion motor activity 20/1486 151/18639 0.132450331125828 1.66133359478755 0.0170071132538226 0.128017246042187 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 20/1486 151/18639 0.132450331125828 1.66133359478755 0.0170071132538226 0.128017246042187 GO:0140849 ATP-dependent H2AZ histone chaperone activity 20/1486 151/18639 0.132450331125828 1.66133359478755 0.0170071132538226 0.128017246042187 GO:0003712 transcription coregulator activity 53/1486 495/18639 0.107070707070707 1.34299522819038 0.0170390730283822 0.128017246042187 GO:0016004 phospholipase activator activity 5/1486 20/18639 0.25 3.13576716016151 0.0180358013218775 0.132986537563109 GO:0003777 microtubule motor activity 11/1486 68/18639 0.161764705882353 2.02902580951627 0.0180574055159305 0.132986537563109 GO:0015616 DNA translocase activity 20/1486 152/18639 0.131578947368421 1.65040376850606 0.0181662870926839 0.132986537563109 GO:0140674 ATP-dependent histone chaperone activity 20/1486 152/18639 0.131578947368421 1.65040376850606 0.0181662870926839 0.132986537563109 GO:0004712 protein serine/threonine/tyrosine kinase activity 8/1486 43/18639 0.186046511627907 2.33359416570159 0.0188581081570535 0.137171716658313 GO:0061775 cohesin loader activity 20/1486 153/18639 0.130718954248366 1.63961681577072 0.0193860042938837 0.139406460147636 GO:0004714 transmembrane receptor protein tyrosine kinase activity 10/1486 60/18639 0.166666666666667 2.09051144010767 0.0194094808786989 0.139406460147636 GO:0035401 histone H3Y41 kinase activity 16/1486 115/18639 0.139130434782609 1.74512259348119 0.0201621809961335 0.142150205404216 GO:0140801 histone H2AXY142 kinase activity 16/1486 115/18639 0.139130434782609 1.74512259348119 0.0201621809961335 0.142150205404216 GO:0019199 transmembrane receptor protein kinase activity 12/1486 78/18639 0.153846153846154 1.9297028677917 0.0201649153025245 0.142150205404216 GO:0016866 intramolecular transferase activity 6/1486 28/18639 0.214285714285714 2.68780042299558 0.0208815617034745 0.146299039664834 GO:1990825 sequence-specific mRNA binding 4/1486 14/18639 0.285714285714286 3.58373389732744 0.0210649080356238 0.146683688882209 GO:0009055 electron transfer activity 16/1486 116/18639 0.137931034482759 1.73007843319256 0.0217177664144895 0.150313268153618 GO:0016835 carbon-oxygen lyase activity 12/1486 79/18639 0.151898734177215 1.90527624921206 0.0221104065305959 0.152108941312895 GO:0005003 ephrin receptor activity 9/1486 53/18639 0.169811320754717 2.12995505218517 0.0231281375765123 0.157216268526054 GO:0005005 transmembrane-ephrin receptor activity 9/1486 53/18639 0.169811320754717 2.12995505218517 0.0231281375765123 0.157216268526054 GO:0003785 actin monomer binding 6/1486 29/18639 0.206896551724138 2.59511764978883 0.0246038617209947 0.166258047842462 GO:0030246 carbohydrate binding 32/1486 280/18639 0.114285714285714 1.43349355893097 0.0249592993800975 0.167667764071008 GO:0015485 cholesterol binding 9/1486 54/18639 0.166666666666667 2.09051144010767 0.0258570536665803 0.172682779457513 GO:0016846 carbon-sulfur lyase activity 4/1486 15/18639 0.266666666666667 3.34481830417227 0.0269516890823153 0.175879022468595 GO:0031386 protein tag activity 4/1486 15/18639 0.266666666666667 3.34481830417227 0.0269516890823153 0.175879022468595 GO:0050780 dopamine receptor binding 4/1486 15/18639 0.266666666666667 3.34481830417227 0.0269516890823153 0.175879022468595 GO:0141047 molecular tag activity 4/1486 15/18639 0.266666666666667 3.34481830417227 0.0269516890823153 0.175879022468595 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 8/1486 46/18639 0.173913043478261 2.18140324185148 0.0275038958956509 0.177096232330818 GO:0019001 guanyl nucleotide binding 43/1486 400/18639 0.1075 1.34837987886945 0.0276034407660995 0.177096232330818 GO:0032561 guanyl ribonucleotide binding 43/1486 400/18639 0.1075 1.34837987886945 0.0276034407660995 0.177096232330818 GO:0042162 telomeric DNA binding 7/1486 38/18639 0.184210526315789 2.31056527590848 0.0286402272156316 0.18170633044584 GO:0043531 ADP binding 7/1486 38/18639 0.184210526315789 2.31056527590848 0.0286402272156316 0.18170633044584 GO:0004713 protein tyrosine kinase activity 18/1486 140/18639 0.128571428571429 1.61268025379735 0.0296402405185668 0.187011904266316 GO:0031072 heat shock protein binding 17/1486 131/18639 0.129770992366412 1.62772646481666 0.0313125756241395 0.196477809685535 GO:0004866 endopeptidase inhibitor activity 20/1486 161/18639 0.124223602484472 1.55814517275106 0.031556986063281 0.196929388438617 GO:0004602 glutathione peroxidase activity 5/1486 23/18639 0.217391304347826 2.72675405231435 0.0321100639665333 0.199291810053158 GO:0016776 phosphotransferase activity, phosphate group as acceptor 7/1486 39/18639 0.179487179487179 2.25132001242365 0.0325858374032874 0.201151493592185 GO:0004708 MAP kinase kinase activity 4/1486 16/18639 0.25 3.13576716016151 0.0337246165349562 0.203775196205926 GO:0005159 insulin-like growth factor receptor binding 4/1486 16/18639 0.25 3.13576716016151 0.0337246165349562 0.203775196205926 GO:0017070 U6 snRNA binding 4/1486 16/18639 0.25 3.13576716016151 0.0337246165349562 0.203775196205926 GO:0097027 ubiquitin-protein transferase activator activity 4/1486 16/18639 0.25 3.13576716016151 0.0337246165349562 0.203775196205926 GO:0003725 double-stranded RNA binding 11/1486 75/18639 0.146666666666667 1.83965006729475 0.034851757030311 0.209477402782185 GO:0061135 endopeptidase regulator activity 22/1486 184/18639 0.119565217391304 1.49971472877289 0.0364955808166297 0.209726945176125 GO:0004177 aminopeptidase activity 7/1486 40/18639 0.175 2.19503701211306 0.0368780480401257 0.209726945176125 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 7/1486 40/18639 0.175 2.19503701211306 0.0368780480401257 0.209726945176125 GO:0050997 quaternary ammonium group binding 7/1486 40/18639 0.175 2.19503701211306 0.0368780480401257 0.209726945176125 GO:0033218 amide binding 28/1486 247/18639 0.11336032388664 1.42188632363599 0.0373756597492069 0.209726945176125 GO:0001091 RNA polymerase II general transcription initiation factor binding 5/1486 24/18639 0.208333333333333 2.61313930013459 0.0379819640332494 0.209726945176125 GO:0050699 WW domain binding 5/1486 24/18639 0.208333333333333 2.61313930013459 0.0379819640332494 0.209726945176125 GO:0060229 lipase activator activity 5/1486 24/18639 0.208333333333333 2.61313930013459 0.0379819640332494 0.209726945176125 GO:0004867 serine-type endopeptidase inhibitor activity 13/1486 95/18639 0.136842105263158 1.7164199192463 0.0381851405139677 0.209726945176125 GO:0031369 translation initiation factor binding 6/1486 32/18639 0.1875 2.35182537012113 0.0383356651801353 0.209726945176125 GO:0005004 GPI-linked ephrin receptor activity 8/1486 49/18639 0.163265306122449 2.04784794132996 0.0385662508642611 0.209726945176125 GO:0005008 hepatocyte growth factor receptor activity 8/1486 49/18639 0.163265306122449 2.04784794132996 0.0385662508642611 0.209726945176125 GO:0005009 insulin receptor activity 8/1486 49/18639 0.163265306122449 2.04784794132996 0.0385662508642611 0.209726945176125 GO:0005011 macrophage colony-stimulating factor receptor activity 8/1486 49/18639 0.163265306122449 2.04784794132996 0.0385662508642611 0.209726945176125 GO:0005018 platelet-derived growth factor alpha-receptor activity 8/1486 49/18639 0.163265306122449 2.04784794132996 0.0385662508642611 0.209726945176125 GO:0005020 stem cell factor receptor activity 8/1486 49/18639 0.163265306122449 2.04784794132996 0.0385662508642611 0.209726945176125 GO:0008288 boss receptor activity 8/1486 49/18639 0.163265306122449 2.04784794132996 0.0385662508642611 0.209726945176125 GO:0036332 placental growth factor receptor activity 8/1486 49/18639 0.163265306122449 2.04784794132996 0.0385662508642611 0.209726945176125 GO:0038062 protein tyrosine kinase collagen receptor activity 8/1486 49/18639 0.163265306122449 2.04784794132996 0.0385662508642611 0.209726945176125 GO:0060175 brain-derived neurotrophic factor receptor activity 8/1486 49/18639 0.163265306122449 2.04784794132996 0.0385662508642611 0.209726945176125 GO:0003680 minor groove of adenine-thymine-rich DNA binding 3/1486 10/18639 0.3 3.76292059219381 0.0396791872936332 0.209785332820968 GO:0005345 purine nucleobase transmembrane transporter activity 3/1486 10/18639 0.3 3.76292059219381 0.0396791872936332 0.209785332820968 GO:0005528 FK506 binding 3/1486 10/18639 0.3 3.76292059219381 0.0396791872936332 0.209785332820968 GO:0015924 mannosyl-oligosaccharide mannosidase activity 3/1486 10/18639 0.3 3.76292059219381 0.0396791872936332 0.209785332820968 GO:0016868 intramolecular phosphotransferase activity 3/1486 10/18639 0.3 3.76292059219381 0.0396791872936332 0.209785332820968 GO:0031996 thioesterase binding 3/1486 10/18639 0.3 3.76292059219381 0.0396791872936332 0.209785332820968 GO:0005525 GTP binding 40/1486 378/18639 0.105820105820106 1.32730885086201 0.0403115786037661 0.212146648688944 GO:0005092 GDP-dissociation inhibitor activity 4/1486 17/18639 0.235294117647059 2.9513102683873 0.041397163680758 0.215558504023259 GO:1990226 histone methyltransferase binding 4/1486 17/18639 0.235294117647059 2.9513102683873 0.041397163680758 0.215558504023259 GO:0061650 ubiquitin-like protein conjugating enzyme activity 7/1486 41/18639 0.170731707317073 2.14149952401274 0.0415261566419589 0.215558504023259 GO:0005006 epidermal growth factor receptor activity 8/1486 50/18639 0.16 2.00689098250336 0.0428306110798132 0.218956629037148 GO:0005017 platelet-derived growth factor receptor activity 8/1486 50/18639 0.16 2.00689098250336 0.0428306110798132 0.218956629037148 GO:0005019 platelet-derived growth factor beta-receptor activity 8/1486 50/18639 0.16 2.00689098250336 0.0428306110798132 0.218956629037148 GO:0045309 protein phosphorylated amino acid binding 9/1486 59/18639 0.152542372881356 1.91334945365787 0.0429477100738363 0.218956629037148 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 6/1486 33/18639 0.181818181818182 2.28055793466291 0.0438106862763864 0.222363572122814 GO:0019211 phosphatase activator activity 5/1486 25/18639 0.2 2.50861372812921 0.0444676456282929 0.22469934206863 GO:0042056 chemoattractant activity 7/1486 42/18639 0.166666666666667 2.09051144010767 0.0465380777661136 0.233297395775795 GO:0005010 insulin-like growth factor receptor activity 8/1486 51/18639 0.156862745098039 1.96754017892487 0.0473949175306343 0.233297395775795 GO:0005021 vascular endothelial growth factor receptor activity 8/1486 51/18639 0.156862745098039 1.96754017892487 0.0473949175306343 0.233297395775795 GO:0005030 neurotrophin receptor activity 8/1486 51/18639 0.156862745098039 1.96754017892487 0.0473949175306343 0.233297395775795 GO:0005048 signal sequence binding 8/1486 51/18639 0.156862745098039 1.96754017892487 0.0473949175306343 0.233297395775795 GO:0016830 carbon-carbon lyase activity 8/1486 51/18639 0.156862745098039 1.96754017892487 0.0473949175306343 0.233297395775795 GO:0005496 steroid binding 14/1486 108/18639 0.12962962962963 1.62595334230597 0.0479123509238244 0.234832209248959 GO:0030414 peptidase inhibitor activity 20/1486 169/18639 0.118343195266272 1.48438682137823 0.0486956266362771 0.237651306062515 GO:0003746 translation elongation factor activity 4/1486 18/18639 0.222222222222222 2.78734858681023 0.0499723772811987 0.240795168165101 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 4/1486 18/18639 0.222222222222222 2.78734858681023 0.0499723772811987 0.240795168165101 GO:0031690 adrenergic receptor binding 4/1486 18/18639 0.222222222222222 2.78734858681023 0.0499723772811987 0.240795168165101 GO:0035591 signaling adaptor activity 16/1486 129/18639 0.124031007751938 1.55572944380106 0.0510681376374268 0.241385004964041 GO:0010854 adenylate cyclase regulator activity 3/1486 11/18639 0.272727272727273 3.42083690199437 0.0514021238136068 0.241385004964041 GO:0015205 nucleobase transmembrane transporter activity 3/1486 11/18639 0.272727272727273 3.42083690199437 0.0514021238136068 0.241385004964041 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 3/1486 11/18639 0.272727272727273 3.42083690199437 0.0514021238136068 0.241385004964041 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 3/1486 11/18639 0.272727272727273 3.42083690199437 0.0514021238136068 0.241385004964041 GO:0050998 nitric-oxide synthase binding 3/1486 11/18639 0.272727272727273 3.42083690199437 0.0514021238136068 0.241385004964041 GO:0070006 metalloaminopeptidase activity 5/1486 26/18639 0.192307692307692 2.41212858473962 0.051574379344331 0.241385004964041 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 21/1486 181/18639 0.116022099447514 1.45527315720203 0.0527707918411124 0.245976507275716 GO:0061631 ubiquitin conjugating enzyme activity 6/1486 35/18639 0.171428571428571 2.15024033839646 0.0561596483336689 0.260708611370122 GO:0038064 collagen receptor activity 8/1486 53/18639 0.150943396226415 1.89329337972016 0.0574445343627116 0.265593758065654 GO:0019205 nucleobase-containing compound kinase activity 7/1486 44/18639 0.159090909090909 1.99548819283005 0.0576778212062677 0.265597063780474 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 5/1486 27/18639 0.185185185185185 2.32279048900852 0.0593049650361551 0.270207149897279 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 4/1486 19/18639 0.210526315789474 2.64064602960969 0.0594436571844019 0.270207149897279 GO:0097001 ceramide binding 4/1486 19/18639 0.210526315789474 2.64064602960969 0.0594436571844019 0.270207149897279 GO:0061134 peptidase regulator activity 25/1486 226/18639 0.110619469026549 1.38750759299182 0.0596253955990493 0.270207149897279 GO:0043178 alcohol binding 12/1486 92/18639 0.130434782608696 1.63605243138861 0.0613223135112489 0.276798743200973 GO:0003925 G protein activity 8/1486 54/18639 0.148148148148148 1.85823239120682 0.0629380092663867 0.281531259799106 GO:0004869 cysteine-type endopeptidase inhibitor activity 6/1486 36/18639 0.166666666666667 2.09051144010767 0.0630425589774351 0.281531259799106 GO:0005527 macrolide binding 3/1486 12/18639 0.25 3.13576716016151 0.0645894834215111 0.281531259799106 GO:0016801 hydrolase activity, acting on ether bonds 3/1486 12/18639 0.25 3.13576716016151 0.0645894834215111 0.281531259799106 GO:0016803 ether hydrolase activity 3/1486 12/18639 0.25 3.13576716016151 0.0645894834215111 0.281531259799106 GO:0017166 vinculin binding 3/1486 12/18639 0.25 3.13576716016151 0.0645894834215111 0.281531259799106 GO:0045295 gamma-catenin binding 3/1486 12/18639 0.25 3.13576716016151 0.0645894834215111 0.281531259799106 GO:0097371 MDM2/MDM4 family protein binding 3/1486 12/18639 0.25 3.13576716016151 0.0645894834215111 0.281531259799106 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/1486 12/18639 0.25 3.13576716016151 0.0645894834215111 0.281531259799106 GO:0005506 iron ion binding 18/1486 154/18639 0.116883116883117 1.46607295799759 0.0651192391944394 0.282761107072433 GO:0046625 sphingolipid binding 5/1486 28/18639 0.178571428571429 2.23983368582965 0.0676578788041292 0.291567160733266 GO:0046875 ephrin receptor binding 5/1486 28/18639 0.178571428571429 2.23983368582965 0.0676578788041292 0.291567160733266 GO:0140313 molecular sequestering activity 8/1486 55/18639 0.145454545454545 1.82444634773033 0.0687477176900949 0.2951499759477 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 4/1486 20/18639 0.2 2.50861372812921 0.069795621150033 0.295209627234584 GO:0030742 GTP-dependent protein binding 4/1486 20/18639 0.2 2.50861372812921 0.069795621150033 0.295209627234584 GO:0031418 L-ascorbic acid binding 4/1486 20/18639 0.2 2.50861372812921 0.069795621150033 0.295209627234584 GO:0140664 ATP-dependent DNA damage sensor activity 4/1486 20/18639 0.2 2.50861372812921 0.069795621150033 0.295209627234584 GO:0043394 proteoglycan binding 6/1486 37/18639 0.162162162162162 2.03401113091557 0.0703997123368749 0.296665946452809 GO:0017124 SH3 domain binding 14/1486 115/18639 0.121739130434783 1.52698226929604 0.0734551447551182 0.308403585699798 GO:0019212 phosphatase inhibitor activity 8/1486 56/18639 0.142857142857143 1.79186694866372 0.0748752422366107 0.313214383275492 GO:0140297 DNA-binding transcription factor binding 48/1486 488/18639 0.0983606557377049 1.23374445645699 0.0758660279520398 0.316200744238064 GO:0005109 frizzled binding 6/1486 38/18639 0.157894736842105 1.98048452220727 0.0782296157971082 0.322836920406171 GO:0005542 folic acid binding 3/1486 13/18639 0.230769230769231 2.89455430168755 0.0791544113079928 0.322836920406171 GO:0008035 high-density lipoprotein particle binding 3/1486 13/18639 0.230769230769231 2.89455430168755 0.0791544113079928 0.322836920406171 GO:0019855 calcium channel inhibitor activity 3/1486 13/18639 0.230769230769231 2.89455430168755 0.0791544113079928 0.322836920406171 GO:0061459 L-arginine transmembrane transporter activity 3/1486 13/18639 0.230769230769231 2.89455430168755 0.0791544113079928 0.322836920406171 GO:0070700 BMP receptor binding 3/1486 13/18639 0.230769230769231 2.89455430168755 0.0791544113079928 0.322836920406171 GO:0019200 carbohydrate kinase activity 4/1486 21/18639 0.19047619047619 2.38915593155162 0.0810050186648436 0.328041600408693 GO:0072542 protein phosphatase activator activity 4/1486 21/18639 0.19047619047619 2.38915593155162 0.0810050186648436 0.328041600408693 GO:0019208 phosphatase regulator activity 14/1486 117/18639 0.11965811965812 1.50088000828243 0.0821283068292355 0.331415287628929 GO:0016500 protein-hormone receptor activity 9/1486 67/18639 0.134328358208955 1.68488981740021 0.0835905182475391 0.336128069854541 GO:0016769 transferase activity, transferring nitrogenous groups 5/1486 30/18639 0.166666666666667 2.09051144010767 0.0862041697533596 0.345421620555567 GO:0030295 protein kinase activator activity 16/1486 139/18639 0.115107913669065 1.44380646223264 0.0873139550978098 0.348645233292653 GO:0042393 histone binding 26/1486 247/18639 0.105263157894737 1.32032301480485 0.0885241700297999 0.352246000606382 GO:0030145 manganese ion binding 9/1486 68/18639 0.132352941176471 1.66011202596786 0.0898875076125663 0.35642893643594 GO:0003714 transcription corepressor activity 22/1486 204/18639 0.107843137254902 1.35268387301085 0.0907052813537752 0.358427097944676 GO:0016763 pentosyltransferase activity 7/1486 49/18639 0.142857142857143 1.79186694866372 0.0921662890029446 0.362944489797803 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 3/1486 14/18639 0.214285714285714 2.68780042299558 0.0949970031095482 0.369655956696721 GO:0032036 myosin heavy chain binding 3/1486 14/18639 0.214285714285714 2.68780042299558 0.0949970031095482 0.369655956696721 GO:0036002 pre-mRNA binding 8/1486 59/18639 0.135593220338983 1.70075506991811 0.0951653688868967 0.369655956696721 GO:0070063 RNA polymerase binding 8/1486 59/18639 0.135593220338983 1.70075506991811 0.0951653688868967 0.369655956696721 GO:0017147 Wnt-protein binding 5/1486 31/18639 0.161290322580645 2.02307558720097 0.0963747935884003 0.370572438646307 GO:0070325 lipoprotein particle receptor binding 5/1486 31/18639 0.161290322580645 2.02307558720097 0.0963747935884003 0.370572438646307 GO:0072349 modified amino acid transmembrane transporter activity 5/1486 31/18639 0.161290322580645 2.02307558720097 0.0963747935884003 0.370572438646307 GO:0001098 basal transcription machinery binding 8/1486 60/18639 0.133333333333333 1.67240915208614 0.102559807911663 0.389113955598401 GO:0001099 basal RNA polymerase II transcription machinery binding 8/1486 60/18639 0.133333333333333 1.67240915208614 0.102559807911663 0.389113955598401 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 8/1486 60/18639 0.133333333333333 1.67240915208614 0.102559807911663 0.389113955598401 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 8/1486 60/18639 0.133333333333333 1.67240915208614 0.102559807911663 0.389113955598401 GO:0016758 hexosyltransferase activity 21/1486 197/18639 0.106598984771574 1.33707838301303 0.10556545427733 0.398482785464583 GO:0099186 structural constituent of postsynapse 4/1486 23/18639 0.173913043478261 2.18140324185148 0.105869370067738 0.398482785464583 GO:0043425 bHLH transcription factor binding 5/1486 32/18639 0.15625 1.95985447510094 0.107122780330672 0.398482785464583 GO:0071813 lipoprotein particle binding 5/1486 32/18639 0.15625 1.95985447510094 0.107122780330672 0.398482785464583 GO:0071814 protein-lipid complex binding 5/1486 32/18639 0.15625 1.95985447510094 0.107122780330672 0.398482785464583 GO:0140142 nucleocytoplasmic carrier activity 5/1486 32/18639 0.15625 1.95985447510094 0.107122780330672 0.398482785464583 GO:0003924 GTPase activity 33/1486 331/18639 0.0996978851963746 1.25051741734537 0.107806027545158 0.399256747661657 GO:0072341 modified amino acid binding 11/1486 91/18639 0.120879120879121 1.51619511040776 0.108030065698294 0.399256747661657 GO:0031406 carboxylic acid binding 20/1486 187/18639 0.106951871657754 1.34150466744877 0.109358526689231 0.40286270154549 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 8/1486 61/18639 0.131147540983607 1.64499260860932 0.11026493462274 0.403512664687315 GO:0140299 molecular sensor activity 9/1486 71/18639 0.126760563380282 1.58996644740583 0.110403812414689 0.403512664687315 GO:0004129 cytochrome-c oxidase activity 3/1486 15/18639 0.2 2.50861372812921 0.112008331616356 0.403512664687315 GO:0004559 alpha-mannosidase activity 3/1486 15/18639 0.2 2.50861372812921 0.112008331616356 0.403512664687315 GO:0005041 low-density lipoprotein particle receptor activity 3/1486 15/18639 0.2 2.50861372812921 0.112008331616356 0.403512664687315 GO:0033130 acetylcholine receptor binding 3/1486 15/18639 0.2 2.50861372812921 0.112008331616356 0.403512664687315 GO:0120283 protein serine/threonine kinase binding 3/1486 15/18639 0.2 2.50861372812921 0.112008331616356 0.403512664687315 GO:0035198 miRNA binding 6/1486 42/18639 0.142857142857143 1.79186694866372 0.114168535043475 0.410001468615248 GO:0043177 organic acid binding 20/1486 189/18639 0.105820105820106 1.32730885086201 0.118150778641282 0.42297237996346 GO:0050431 transforming growth factor beta binding 4/1486 24/18639 0.166666666666667 2.09051144010767 0.119446851274636 0.423155973580869 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 4/1486 24/18639 0.166666666666667 2.09051144010767 0.119446851274636 0.423155973580869 GO:0140612 DNA damage sensor activity 4/1486 24/18639 0.166666666666667 2.09051144010767 0.119446851274636 0.423155973580869 GO:0016757 glycosyltransferase activity 27/1486 267/18639 0.101123595505618 1.26840019961589 0.119684220198442 0.423155973580869 GO:0002020 protease binding 15/1486 136/18639 0.110294117647059 1.38342668830655 0.124731684351393 0.439640689905217 GO:1901682 sulfur compound transmembrane transporter activity 8/1486 63/18639 0.126984126984127 1.59277062103442 0.126589024391671 0.444083282354122 GO:0001221 transcription coregulator binding 13/1486 115/18639 0.11304347826087 1.41791210720346 0.12700758576719 0.444083282354122 GO:0015923 mannosidase activity 3/1486 16/18639 0.1875 2.35182537012113 0.130073804327449 0.444083282354122 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 3/1486 16/18639 0.1875 2.35182537012113 0.130073804327449 0.444083282354122 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/1486 16/18639 0.1875 2.35182537012113 0.130073804327449 0.444083282354122 GO:0043023 ribosomal large subunit binding 3/1486 16/18639 0.1875 2.35182537012113 0.130073804327449 0.444083282354122 GO:0055102 lipase inhibitor activity 3/1486 16/18639 0.1875 2.35182537012113 0.130073804327449 0.444083282354122 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 5/1486 34/18639 0.147058823529412 1.84456891774206 0.130269614350815 0.444083282354122 GO:0016831 carboxy-lyase activity 5/1486 34/18639 0.147058823529412 1.84456891774206 0.130269614350815 0.444083282354122 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 5/1486 34/18639 0.147058823529412 1.84456891774206 0.130269614350815 0.444083282354122 GO:0030332 cyclin binding 5/1486 34/18639 0.147058823529412 1.84456891774206 0.130269614350815 0.444083282354122 GO:0019209 kinase activator activity 16/1486 148/18639 0.108108108108108 1.35600742061038 0.131313826390943 0.446310683745407 GO:0008483 transaminase activity 4/1486 25/18639 0.16 2.00689098250336 0.133728604731082 0.451828599416852 GO:0042974 nuclear retinoic acid receptor binding 4/1486 25/18639 0.16 2.00689098250336 0.133728604731082 0.451828599416852 GO:0017069 snRNA binding 7/1486 54/18639 0.12962962962963 1.62595334230597 0.135942357511565 0.455267367384773 GO:0051287 NAD binding 7/1486 54/18639 0.12962962962963 1.62595334230597 0.135942357511565 0.455267367384773 GO:0140463 chromatin-protein adaptor activity 7/1486 54/18639 0.12962962962963 1.62595334230597 0.135942357511565 0.455267367384773 GO:0016229 steroid dehydrogenase activity 5/1486 35/18639 0.142857142857143 1.79186694866372 0.142621275353673 0.476238293724837 GO:0038024 cargo receptor activity 8/1486 65/18639 0.123076923076923 1.54376229423336 0.144092314807291 0.47974759040795 GO:0050750 low-density lipoprotein particle receptor binding 4/1486 26/18639 0.153846153846154 1.9297028677917 0.148665736619583 0.483649787833363 GO:0004029 aldehyde dehydrogenase (NAD+) activity 3/1486 17/18639 0.176470588235294 2.21348270129048 0.149075941608882 0.483649787833363 GO:0008429 phosphatidylethanolamine binding 3/1486 17/18639 0.176470588235294 2.21348270129048 0.149075941608882 0.483649787833363 GO:0016018 cyclosporin A binding 3/1486 17/18639 0.176470588235294 2.21348270129048 0.149075941608882 0.483649787833363 GO:0017110 nucleoside diphosphate phosphatase activity 3/1486 17/18639 0.176470588235294 2.21348270129048 0.149075941608882 0.483649787833363 GO:0030169 low-density lipoprotein particle binding 3/1486 17/18639 0.176470588235294 2.21348270129048 0.149075941608882 0.483649787833363 GO:0046965 nuclear retinoid X receptor binding 3/1486 17/18639 0.176470588235294 2.21348270129048 0.149075941608882 0.483649787833363 GO:0070402 NADPH binding 3/1486 17/18639 0.176470588235294 2.21348270129048 0.149075941608882 0.483649787833363 GO:0070492 oligosaccharide binding 3/1486 17/18639 0.176470588235294 2.21348270129048 0.149075941608882 0.483649787833363 GO:0030291 protein serine/threonine kinase inhibitor activity 6/1486 46/18639 0.130434782608696 1.63605243138861 0.156997826929818 0.507907984005246 GO:0004252 serine-type endopeptidase activity 18/1486 176/18639 0.102272727272727 1.28281383824789 0.165041959876525 0.532423497680768 GO:0022829 wide pore channel activity 5/1486 37/18639 0.135135135135135 1.69500927576298 0.168746683415374 0.54028005436915 GO:0000900 mRNA regulatory element binding translation repressor activity 3/1486 18/18639 0.166666666666667 2.09051144010767 0.168896654474419 0.54028005436915 GO:0030228 lipoprotein particle receptor activity 3/1486 18/18639 0.166666666666667 2.09051144010767 0.168896654474419 0.54028005436915 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 8/1486 68/18639 0.117647058823529 1.47565513419365 0.172426637765842 0.548499220971008 GO:1990841 promoter-specific chromatin binding 8/1486 68/18639 0.117647058823529 1.47565513419365 0.172426637765842 0.548499220971008 GO:0061980 regulatory RNA binding 7/1486 58/18639 0.120689655172414 1.51381862904349 0.177037123830889 0.554657955011569 GO:0008514 organic anion transmembrane transporter activity 26/1486 269/18639 0.0966542750929368 1.21234120690259 0.177505810482922 0.554657955011569 GO:0045499 chemorepellent activity 4/1486 28/18639 0.142857142857143 1.79186694866372 0.180298217301404 0.554657955011569 GO:0000146 microfilament motor activity 5/1486 38/18639 0.131578947368421 1.65040376850606 0.182461390630263 0.554657955011569 GO:0042887 amide transmembrane transporter activity 5/1486 38/18639 0.131578947368421 1.65040376850606 0.182461390630263 0.554657955011569 GO:0000049 tRNA binding 9/1486 80/18639 0.1125 1.41109522207268 0.185752100507249 0.554657955011569 GO:0000182 rDNA binding 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:0005337 nucleoside transmembrane transporter activity 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:0008190 eukaryotic initiation factor 4E binding 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:0008641 ubiquitin-like modifier activating enzyme activity 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:0030957 Tat protein binding 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:0031957 very long-chain fatty acid-CoA ligase activity 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:0032356 oxidized DNA binding 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:0035256 G protein-coupled glutamate receptor binding 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:0035374 chondroitin sulfate binding 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:0051880 G-quadruplex DNA binding 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:0097177 mitochondrial ribosome binding 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:0098505 G-rich strand telomeric DNA binding 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:0099122 RNA polymerase II C-terminal domain binding 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:0140940 histone H2A methyltransferase activity 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:1990259 histone H2AQ104 methyltransferase activity 2/1486 10/18639 0.2 2.50861372812921 0.186839958473273 0.554657955011569 GO:0070888 E-box binding 7/1486 59/18639 0.11864406779661 1.48816068617834 0.188058321611811 0.554657955011569 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 3/1486 19/18639 0.157894736842105 1.98048452220727 0.189419091466298 0.554657955011569 GO:0005346 purine ribonucleotide transmembrane transporter activity 3/1486 19/18639 0.157894736842105 1.98048452220727 0.189419091466298 0.554657955011569 GO:0030506 ankyrin binding 3/1486 19/18639 0.157894736842105 1.98048452220727 0.189419091466298 0.554657955011569 GO:0043395 heparan sulfate proteoglycan binding 3/1486 19/18639 0.157894736842105 1.98048452220727 0.189419091466298 0.554657955011569 GO:0046624 sphingolipid transporter activity 3/1486 19/18639 0.157894736842105 1.98048452220727 0.189419091466298 0.554657955011569 GO:0050145 nucleoside monophosphate kinase activity 3/1486 19/18639 0.157894736842105 1.98048452220727 0.189419091466298 0.554657955011569 GO:0140036 ubiquitin-modified protein reader activity 3/1486 19/18639 0.157894736842105 1.98048452220727 0.189419091466298 0.554657955011569 GO:0008028 monocarboxylic acid transmembrane transporter activity 8/1486 70/18639 0.114285714285714 1.43349355893097 0.192595601692212 0.562517077065233 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 5/1486 39/18639 0.128205128205128 1.60808572315975 0.196569170929421 0.570668233227058 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 4/1486 29/18639 0.137931034482759 1.73007843319256 0.196885537558197 0.570668233227058 GO:0097472 cyclin-dependent protein kinase activity 4/1486 29/18639 0.137931034482759 1.73007843319256 0.196885537558197 0.570668233227058 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 3/1486 20/18639 0.15 1.8814602960969 0.210529115639756 0.588461627751644 GO:0010851 cyclase regulator activity 3/1486 20/18639 0.15 1.8814602960969 0.210529115639756 0.588461627751644 GO:0042288 MHC class I protein binding 3/1486 20/18639 0.15 1.8814602960969 0.210529115639756 0.588461627751644 GO:0061608 nuclear import signal receptor activity 3/1486 20/18639 0.15 1.8814602960969 0.210529115639756 0.588461627751644 GO:0061791 GTPase motor activity 5/1486 40/18639 0.125 1.56788358008075 0.211037577299176 0.588461627751644 GO:1990606 membrane scission GTPase motor activity 5/1486 40/18639 0.125 1.56788358008075 0.211037577299176 0.588461627751644 GO:0008106 alcohol dehydrogenase (NADP+) activity 4/1486 30/18639 0.133333333333333 1.67240915208614 0.213913440297403 0.588461627751644 GO:0031210 phosphatidylcholine binding 4/1486 30/18639 0.133333333333333 1.67240915208614 0.213913440297403 0.588461627751644 GO:0033612 receptor serine/threonine kinase binding 4/1486 30/18639 0.133333333333333 1.67240915208614 0.213913440297403 0.588461627751644 GO:0035925 mRNA 3'-UTR AU-rich region binding 4/1486 30/18639 0.133333333333333 1.67240915208614 0.213913440297403 0.588461627751644 GO:0098918 structural constituent of synapse 4/1486 30/18639 0.133333333333333 1.67240915208614 0.213913440297403 0.588461627751644 GO:0042562 hormone binding 10/1486 94/18639 0.106382978723404 1.33436900432405 0.215115850277058 0.588461627751644 GO:0000099 sulfur amino acid transmembrane transporter activity 2/1486 11/18639 0.181818181818182 2.28055793466291 0.21693725506431 0.588461627751644 GO:0002162 dystroglycan binding 2/1486 11/18639 0.181818181818182 2.28055793466291 0.21693725506431 0.588461627751644 GO:0005225 volume-sensitive anion channel activity 2/1486 11/18639 0.181818181818182 2.28055793466291 0.21693725506431 0.588461627751644 GO:0008046 axon guidance receptor activity 2/1486 11/18639 0.181818181818182 2.28055793466291 0.21693725506431 0.588461627751644 GO:0008199 ferric iron binding 2/1486 11/18639 0.181818181818182 2.28055793466291 0.21693725506431 0.588461627751644 GO:0015217 ADP transmembrane transporter activity 2/1486 11/18639 0.181818181818182 2.28055793466291 0.21693725506431 0.588461627751644 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 2/1486 11/18639 0.181818181818182 2.28055793466291 0.21693725506431 0.588461627751644 GO:0032794 GTPase activating protein binding 2/1486 11/18639 0.181818181818182 2.28055793466291 0.21693725506431 0.588461627751644 GO:0034056 estrogen response element binding 2/1486 11/18639 0.181818181818182 2.28055793466291 0.21693725506431 0.588461627751644 GO:0034713 type I transforming growth factor beta receptor binding 2/1486 11/18639 0.181818181818182 2.28055793466291 0.21693725506431 0.588461627751644 GO:0045294 alpha-catenin binding 2/1486 11/18639 0.181818181818182 2.28055793466291 0.21693725506431 0.588461627751644 GO:0047676 arachidonate-CoA ligase activity 2/1486 11/18639 0.181818181818182 2.28055793466291 0.21693725506431 0.588461627751644 GO:0048185 activin binding 2/1486 11/18639 0.181818181818182 2.28055793466291 0.21693725506431 0.588461627751644 GO:0097493 structural molecule activity conferring elasticity 2/1486 11/18639 0.181818181818182 2.28055793466291 0.21693725506431 0.588461627751644 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/1486 11/18639 0.181818181818182 2.28055793466291 0.21693725506431 0.588461627751644 GO:0016597 amino acid binding 6/1486 51/18639 0.117647058823529 1.47565513419365 0.218656358776093 0.590320476884867 GO:0030544 Hsp70 protein binding 6/1486 51/18639 0.117647058823529 1.47565513419365 0.218656358776093 0.590320476884867 GO:0035173 histone kinase activity 33/1486 360/18639 0.0916666666666667 1.14978129205922 0.224124388731049 0.603655782855798 GO:0001530 lipopolysaccharide binding 5/1486 41/18639 0.121951219512195 1.52964251715195 0.22583348509813 0.603985573728488 GO:0015175 neutral L-amino acid transmembrane transporter activity 5/1486 41/18639 0.121951219512195 1.52964251715195 0.22583348509813 0.603985573728488 GO:0042169 SH2 domain binding 5/1486 41/18639 0.121951219512195 1.52964251715195 0.22583348509813 0.603985573728488 GO:0022853 active monoatomic ion transmembrane transporter activity 12/1486 118/18639 0.101694915254237 1.27556630243858 0.230520829810328 0.609126013331997 GO:0008327 methyl-CpG binding 4/1486 31/18639 0.129032258064516 1.61846046976078 0.231326573143181 0.609126013331997 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 6/1486 52/18639 0.115384615384615 1.44727715084377 0.231868784667274 0.609126013331997 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/1486 21/18639 0.142857142857143 1.79186694866372 0.232116465135575 0.609126013331997 GO:0015174 basic amino acid transmembrane transporter activity 3/1486 21/18639 0.142857142857143 1.79186694866372 0.232116465135575 0.609126013331997 GO:0035613 RNA stem-loop binding 3/1486 21/18639 0.142857142857143 1.79186694866372 0.232116465135575 0.609126013331997 GO:0051010 microtubule plus-end binding 3/1486 21/18639 0.142857142857143 1.79186694866372 0.232116465135575 0.609126013331997 GO:1904047 S-adenosyl-L-methionine binding 3/1486 21/18639 0.142857142857143 1.79186694866372 0.232116465135575 0.609126013331997 GO:0019888 protein phosphatase regulator activity 11/1486 107/18639 0.102803738317757 1.28947434623464 0.232555991079467 0.609126013331997 GO:0016407 acetyltransferase activity 10/1486 96/18639 0.104166666666667 1.30656965006729 0.234209988720539 0.61205447853285 GO:0031491 nucleosome binding 8/1486 74/18639 0.108108108108108 1.35600742061038 0.235615157310809 0.614214296362299 GO:0004520 DNA endonuclease activity 5/1486 42/18639 0.119047619047619 1.49322245721977 0.240923343213624 0.614214296362299 GO:0031492 nucleosomal DNA binding 5/1486 42/18639 0.119047619047619 1.49322245721977 0.240923343213624 0.614214296362299 GO:0048487 beta-tubulin binding 5/1486 42/18639 0.119047619047619 1.49322245721977 0.240923343213624 0.614214296362299 GO:0020037 heme binding 14/1486 142/18639 0.0985915492957746 1.23664057020454 0.241597703429876 0.614214296362299 GO:0004864 protein phosphatase inhibitor activity 6/1486 53/18639 0.113207547169811 1.41997003479012 0.245322821320051 0.614214296362299 GO:0005246 calcium channel regulator activity 6/1486 53/18639 0.113207547169811 1.41997003479012 0.245322821320051 0.614214296362299 GO:0017046 peptide hormone binding 6/1486 53/18639 0.113207547169811 1.41997003479012 0.245322821320051 0.614214296362299 GO:0004032 aldose reductase (NADPH) activity 2/1486 12/18639 0.166666666666667 2.09051144010767 0.24740680939287 0.614214296362299 GO:0004859 phospholipase inhibitor activity 2/1486 12/18639 0.166666666666667 2.09051144010767 0.24740680939287 0.614214296362299 GO:0005049 nuclear export signal receptor activity 2/1486 12/18639 0.166666666666667 2.09051144010767 0.24740680939287 0.614214296362299 GO:0005078 MAP-kinase scaffold activity 2/1486 12/18639 0.166666666666667 2.09051144010767 0.24740680939287 0.614214296362299 GO:0005095 GTPase inhibitor activity 2/1486 12/18639 0.166666666666667 2.09051144010767 0.24740680939287 0.614214296362299 GO:0008179 adenylate cyclase binding 2/1486 12/18639 0.166666666666667 2.09051144010767 0.24740680939287 0.614214296362299 GO:0010853 cyclase activator activity 2/1486 12/18639 0.166666666666667 2.09051144010767 0.24740680939287 0.614214296362299 GO:0015132 prostaglandin transmembrane transporter activity 2/1486 12/18639 0.166666666666667 2.09051144010767 0.24740680939287 0.614214296362299 GO:0015368 calcium:monoatomic cation antiporter activity 2/1486 12/18639 0.166666666666667 2.09051144010767 0.24740680939287 0.614214296362299 GO:0016208 AMP binding 2/1486 12/18639 0.166666666666667 2.09051144010767 0.24740680939287 0.614214296362299 GO:0016840 carbon-nitrogen lyase activity 2/1486 12/18639 0.166666666666667 2.09051144010767 0.24740680939287 0.614214296362299 GO:0035251 UDP-glucosyltransferase activity 2/1486 12/18639 0.166666666666667 2.09051144010767 0.24740680939287 0.614214296362299 GO:0036009 protein-glutamine N-methyltransferase activity 2/1486 12/18639 0.166666666666667 2.09051144010767 0.24740680939287 0.614214296362299 GO:0042301 phosphate ion binding 2/1486 12/18639 0.166666666666667 2.09051144010767 0.24740680939287 0.614214296362299 GO:0043047 single-stranded telomeric DNA binding 2/1486 12/18639 0.166666666666667 2.09051144010767 0.24740680939287 0.614214296362299 GO:0008378 galactosyltransferase activity 4/1486 32/18639 0.125 1.56788358008075 0.249069972116396 0.614336734680183 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/1486 32/18639 0.125 1.56788358008075 0.249069972116396 0.614336734680183 GO:0120015 sterol transfer activity 4/1486 32/18639 0.125 1.56788358008075 0.249069972116396 0.614336734680183 GO:0015399 primary active transmembrane transporter activity 16/1486 166/18639 0.0963855421686747 1.20897047138757 0.249832317540257 0.61488902291158 GO:0031683 G-protein beta/gamma-subunit complex binding 3/1486 22/18639 0.136363636363636 1.71041845099719 0.254075644158218 0.619988003480096 GO:0034062 5'-3' RNA polymerase activity 3/1486 22/18639 0.136363636363636 1.71041845099719 0.254075644158218 0.619988003480096 GO:0097747 RNA polymerase activity 3/1486 22/18639 0.136363636363636 1.71041845099719 0.254075644158218 0.619988003480096 GO:0140035 ubiquitin-like protein reader activity 3/1486 22/18639 0.136363636363636 1.71041845099719 0.254075644158218 0.619988003480096 GO:0008200 ion channel inhibitor activity 5/1486 43/18639 0.116279069767442 1.45849635356349 0.256273408848434 0.622689857244492 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 5/1486 43/18639 0.116279069767442 1.45849635356349 0.256273408848434 0.622689857244492 GO:0019903 protein phosphatase binding 14/1486 144/18639 0.0972222222222222 1.21946500672947 0.257889011032469 0.623567095366736 GO:0019955 cytokine binding 14/1486 144/18639 0.0972222222222222 1.21946500672947 0.257889011032469 0.623567095366736 GO:0051536 iron-sulfur cluster binding 8/1486 76/18639 0.105263157894737 1.32032301480485 0.258272535996906 0.623567095366736 GO:0050661 NADP binding 6/1486 54/18639 0.111111111111111 1.39367429340511 0.258995379296112 0.623993086827341 GO:0019956 chemokine binding 4/1486 33/18639 0.121212121212121 1.52037195644194 0.267089483937721 0.634947784876197 GO:0140311 protein sequestering activity 4/1486 33/18639 0.121212121212121 1.52037195644194 0.267089483937721 0.634947784876197 GO:0051540 metal cluster binding 8/1486 77/18639 0.103896103896104 1.30317596266452 0.269843228291561 0.634947784876197 GO:0001046 core promoter sequence-specific DNA binding 5/1486 44/18639 0.113636363636364 1.42534870916432 0.271849965226163 0.634947784876197 GO:0001223 transcription coactivator binding 5/1486 44/18639 0.113636363636364 1.42534870916432 0.271849965226163 0.634947784876197 GO:0016248 channel inhibitor activity 5/1486 44/18639 0.113636363636364 1.42534870916432 0.271849965226163 0.634947784876197 GO:0030547 signaling receptor inhibitor activity 5/1486 44/18639 0.113636363636364 1.42534870916432 0.271849965226163 0.634947784876197 GO:0043014 alpha-tubulin binding 5/1486 44/18639 0.113636363636364 1.42534870916432 0.271849965226163 0.634947784876197 GO:0000295 adenine nucleotide transmembrane transporter activity 3/1486 23/18639 0.130434782608696 1.63605243138861 0.27630658527179 0.634947784876197 GO:0004022 alcohol dehydrogenase (NAD+) activity 3/1486 23/18639 0.130434782608696 1.63605243138861 0.27630658527179 0.634947784876197 GO:0005158 insulin receptor binding 3/1486 23/18639 0.130434782608696 1.63605243138861 0.27630658527179 0.634947784876197 GO:0005283 amino acid:sodium symporter activity 3/1486 23/18639 0.130434782608696 1.63605243138861 0.27630658527179 0.634947784876197 GO:0043274 phospholipase binding 3/1486 23/18639 0.130434782608696 1.63605243138861 0.27630658527179 0.634947784876197 GO:0005172 vascular endothelial growth factor receptor binding 2/1486 13/18639 0.153846153846154 1.9297028677917 0.27799815449921 0.634947784876197 GO:0009982 pseudouridine synthase activity 2/1486 13/18639 0.153846153846154 1.9297028677917 0.27799815449921 0.634947784876197 GO:0035673 oligopeptide transmembrane transporter activity 2/1486 13/18639 0.153846153846154 1.9297028677917 0.27799815449921 0.634947784876197 GO:0039706 co-receptor binding 2/1486 13/18639 0.153846153846154 1.9297028677917 0.27799815449921 0.634947784876197 GO:0043560 insulin receptor substrate binding 2/1486 13/18639 0.153846153846154 1.9297028677917 0.27799815449921 0.634947784876197 GO:0045159 myosin II binding 2/1486 13/18639 0.153846153846154 1.9297028677917 0.27799815449921 0.634947784876197 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/1486 13/18639 0.153846153846154 1.9297028677917 0.27799815449921 0.634947784876197 GO:0071714 icosanoid transmembrane transporter activity 2/1486 13/18639 0.153846153846154 1.9297028677917 0.27799815449921 0.634947784876197 GO:0071837 HMG box domain binding 2/1486 13/18639 0.153846153846154 1.9297028677917 0.27799815449921 0.634947784876197 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/1486 13/18639 0.153846153846154 1.9297028677917 0.27799815449921 0.634947784876197 GO:0097157 pre-mRNA intronic binding 2/1486 13/18639 0.153846153846154 1.9297028677917 0.27799815449921 0.634947784876197 GO:0140410 monoatomic cation:bicarbonate symporter activity 2/1486 13/18639 0.153846153846154 1.9297028677917 0.27799815449921 0.634947784876197 GO:1901338 catecholamine binding 2/1486 13/18639 0.153846153846154 1.9297028677917 0.27799815449921 0.634947784876197 GO:0008236 serine-type peptidase activity 18/1486 194/18639 0.0927835051546392 1.16378987387437 0.28519278740813 0.647811721933685 GO:0008376 acetylgalactosaminyltransferase activity 4/1486 34/18639 0.117647058823529 1.47565513419365 0.285332133215975 0.647811721933685 GO:0090482 vitamin transmembrane transporter activity 4/1486 34/18639 0.117647058823529 1.47565513419365 0.285332133215975 0.647811721933685 GO:0141110 transporter inhibitor activity 5/1486 45/18639 0.111111111111111 1.39367429340511 0.287619521796925 0.651709313277953 GO:0140789 histone phosphatase activity 13/1486 136/18639 0.0955882352941176 1.19896979653234 0.288360523734928 0.652094491297599 GO:0033293 monocarboxylic acid binding 8/1486 79/18639 0.10126582278481 1.27018416614137 0.293402017173805 0.662183999234161 GO:0016922 nuclear receptor binding 13/1486 137/18639 0.0948905109489051 1.19021819217809 0.29733219322868 0.66627473741279 GO:0008237 metallopeptidase activity 17/1486 184/18639 0.0923913043478261 1.1588704722336 0.298513959458476 0.66627473741279 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/1486 24/18639 0.125 1.56788358008075 0.298715118699955 0.66627473741279 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/1486 24/18639 0.125 1.56788358008075 0.298715118699955 0.66627473741279 GO:0015295 solute:proton symporter activity 3/1486 24/18639 0.125 1.56788358008075 0.298715118699955 0.66627473741279 GO:0030215 semaphorin receptor binding 3/1486 24/18639 0.125 1.56788358008075 0.298715118699955 0.66627473741279 GO:0005154 epidermal growth factor receptor binding 4/1486 35/18639 0.114285714285714 1.43349355893097 0.303746437456272 0.673623540317267 GO:0140566 histone reader activity 4/1486 35/18639 0.114285714285714 1.43349355893097 0.303746437456272 0.673623540317267 GO:0048306 calcium-dependent protein binding 8/1486 80/18639 0.1 1.2543068640646 0.305363119025645 0.673623540317267 GO:0005161 platelet-derived growth factor receptor binding 2/1486 14/18639 0.142857142857143 1.79186694866372 0.308498346397488 0.673623540317267 GO:0005347 ATP transmembrane transporter activity 2/1486 14/18639 0.142857142857143 1.79186694866372 0.308498346397488 0.673623540317267 GO:0008191 metalloendopeptidase inhibitor activity 2/1486 14/18639 0.142857142857143 1.79186694866372 0.308498346397488 0.673623540317267 GO:0008559 ABC-type xenobiotic transporter activity 2/1486 14/18639 0.142857142857143 1.79186694866372 0.308498346397488 0.673623540317267 GO:0019992 diacylglycerol binding 2/1486 14/18639 0.142857142857143 1.79186694866372 0.308498346397488 0.673623540317267 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 2/1486 14/18639 0.142857142857143 1.79186694866372 0.308498346397488 0.673623540317267 GO:0044548 S100 protein binding 2/1486 14/18639 0.142857142857143 1.79186694866372 0.308498346397488 0.673623540317267 GO:0098847 sequence-specific single stranded DNA binding 2/1486 14/18639 0.142857142857143 1.79186694866372 0.308498346397488 0.673623540317267 GO:0017171 serine hydrolase activity 18/1486 198/18639 0.0909090909090909 1.14027896733146 0.315331064533301 0.686298881676896 GO:0070851 growth factor receptor binding 13/1486 139/18639 0.0935251798561151 1.17309275056402 0.315505177653564 0.686298881676896 GO:0141003 histone H2AX kinase activity 31/1486 354/18639 0.0875706214689266 1.09840431598878 0.318367375481133 0.688639596552748 GO:0005504 fatty acid binding 5/1486 47/18639 0.106382978723404 1.33436900432405 0.319605882106792 0.688639596552748 GO:0140938 histone H3 methyltransferase activity 5/1486 47/18639 0.106382978723404 1.33436900432405 0.319605882106792 0.688639596552748 GO:0005537 D-mannose binding 3/1486 25/18639 0.12 1.50516823687752 0.32121327969571 0.688639596552748 GO:0008139 nuclear localization sequence binding 3/1486 25/18639 0.12 1.50516823687752 0.32121327969571 0.688639596552748 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 3/1486 25/18639 0.12 1.50516823687752 0.32121327969571 0.688639596552748 GO:0000993 RNA polymerase II complex binding 4/1486 36/18639 0.111111111111111 1.39367429340511 0.322282673114737 0.688639596552748 GO:0004033 aldo-keto reductase (NADPH) activity 4/1486 36/18639 0.111111111111111 1.39367429340511 0.322282673114737 0.688639596552748 GO:0051213 dioxygenase activity 9/1486 93/18639 0.0967741935483871 1.21384535232058 0.322611369663503 0.688639596552748 GO:0051219 phosphoprotein binding 9/1486 93/18639 0.0967741935483871 1.21384535232058 0.322611369663503 0.688639596552748 GO:0046906 tetrapyrrole binding 14/1486 152/18639 0.0921052631578947 1.15528263795424 0.326523359604718 0.695689695277216 GO:0001786 phosphatidylserine binding 6/1486 59/18639 0.101694915254237 1.27556630243858 0.329821920436916 0.700105266057544 GO:0004879 nuclear receptor activity 6/1486 59/18639 0.101694915254237 1.27556630243858 0.329821920436916 0.700105266057544 GO:0140996 histone H3 kinase activity 31/1486 357/18639 0.0868347338935574 1.08917402761912 0.335698440141536 0.709768947283536 GO:0001664 G protein-coupled receptor binding 26/1486 297/18639 0.0875420875420875 1.09804641298585 0.337985683462139 0.709768947283536 GO:0004467 long-chain fatty acid-CoA ligase activity 2/1486 15/18639 0.133333333333333 1.67240915208614 0.338727579440738 0.709768947283536 GO:0005523 tropomyosin binding 2/1486 15/18639 0.133333333333333 1.67240915208614 0.338727579440738 0.709768947283536 GO:0048531 beta-1,3-galactosyltransferase activity 2/1486 15/18639 0.133333333333333 1.67240915208614 0.338727579440738 0.709768947283536 GO:0051371 muscle alpha-actinin binding 2/1486 15/18639 0.133333333333333 1.67240915208614 0.338727579440738 0.709768947283536 GO:0140161 monocarboxylate:sodium symporter activity 2/1486 15/18639 0.133333333333333 1.67240915208614 0.338727579440738 0.709768947283536 GO:0030551 cyclic nucleotide binding 4/1486 37/18639 0.108108108108108 1.35600742061038 0.3408930961086 0.709768947283536 GO:0042805 actinin binding 4/1486 37/18639 0.108108108108108 1.35600742061038 0.3408930961086 0.709768947283536 GO:0004112 cyclic-nucleotide phosphodiesterase activity 3/1486 26/18639 0.115384615384615 1.44727715084377 0.343719480966509 0.709768947283536 GO:0004529 DNA exonuclease activity 3/1486 26/18639 0.115384615384615 1.44727715084377 0.343719480966509 0.709768947283536 GO:0008198 ferrous iron binding 3/1486 26/18639 0.115384615384615 1.44727715084377 0.343719480966509 0.709768947283536 GO:0015216 purine nucleotide transmembrane transporter activity 3/1486 26/18639 0.115384615384615 1.44727715084377 0.343719480966509 0.709768947283536 GO:0050681 nuclear androgen receptor binding 3/1486 26/18639 0.115384615384615 1.44727715084377 0.343719480966509 0.709768947283536 GO:0070412 R-SMAD binding 3/1486 26/18639 0.115384615384615 1.44727715084377 0.343719480966509 0.709768947283536 GO:0098531 ligand-modulated transcription factor activity 6/1486 60/18639 0.1 1.2543068640646 0.34431873624788 0.709768947283536 GO:0022804 active transmembrane transporter activity 39/1486 457/18639 0.0853391684901532 1.07041504810765 0.351489122650615 0.72324428480541 GO:0004674 protein serine/threonine kinase activity 37/1486 433/18639 0.0854503464203233 1.0718095605171 0.353427698628716 0.7259252371115 GO:0005501 retinoid binding 4/1486 38/18639 0.105263157894737 1.32032301480485 0.359532120282521 0.735816633266379 GO:0019840 isoprenoid binding 4/1486 38/18639 0.105263157894737 1.32032301480485 0.359532120282521 0.735816633266379 GO:0005179 hormone activity 12/1486 132/18639 0.0909090909090909 1.14027896733146 0.361377083498263 0.738269462173553 GO:0001671 ATPase activator activity 3/1486 27/18639 0.111111111111111 1.39367429340511 0.36615857354067 0.73966128075035 GO:0004364 glutathione transferase activity 3/1486 27/18639 0.111111111111111 1.39367429340511 0.36615857354067 0.73966128075035 GO:0005385 zinc ion transmembrane transporter activity 3/1486 27/18639 0.111111111111111 1.39367429340511 0.36615857354067 0.73966128075035 GO:0023026 MHC class II protein complex binding 3/1486 27/18639 0.111111111111111 1.39367429340511 0.36615857354067 0.73966128075035 GO:0005024 transforming growth factor beta receptor activity 2/1486 16/18639 0.125 1.56788358008075 0.36853526159978 0.73966128075035 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1486 16/18639 0.125 1.56788358008075 0.36853526159978 0.73966128075035 GO:0005521 lamin binding 2/1486 16/18639 0.125 1.56788358008075 0.36853526159978 0.73966128075035 GO:0015378 sodium:chloride symporter activity 2/1486 16/18639 0.125 1.56788358008075 0.36853526159978 0.73966128075035 GO:0015562 efflux transmembrane transporter activity 2/1486 16/18639 0.125 1.56788358008075 0.36853526159978 0.73966128075035 GO:0019841 retinol binding 2/1486 16/18639 0.125 1.56788358008075 0.36853526159978 0.73966128075035 GO:0050660 flavin adenine dinucleotide binding 8/1486 86/18639 0.0930232558139535 1.16679708285079 0.3788222229831 0.758973646748597 GO:0004222 metalloendopeptidase activity 10/1486 110/18639 0.0909090909090909 1.14027896733146 0.380803204450365 0.760498301762586 GO:0015293 symporter activity 13/1486 146/18639 0.089041095890411 1.11684857759177 0.380915086346934 0.760498301762586 GO:0005516 calmodulin binding 18/1486 207/18639 0.0869565217391304 1.09070162092574 0.385861608018476 0.769029592246248 GO:0005507 copper ion binding 6/1486 63/18639 0.0952380952380952 1.19457796577581 0.38807200083125 0.770179503823739 GO:0051393 alpha-actinin binding 3/1486 28/18639 0.107142857142857 1.34390021149779 0.388461816289381 0.770179503823739 GO:0051537 2 iron, 2 sulfur cluster binding 3/1486 28/18639 0.107142857142857 1.34390021149779 0.388461816289381 0.770179503823739 GO:0019003 GDP binding 7/1486 75/18639 0.0933333333333333 1.1706864064603 0.39012092674396 0.772128420002776 GO:0030331 nuclear estrogen receptor binding 4/1486 40/18639 0.1 1.2543068640646 0.396725221801699 0.776553175847685 GO:0071949 FAD binding 4/1486 40/18639 0.1 1.2543068640646 0.396725221801699 0.776553175847685 GO:0004659 prenyltransferase activity 2/1486 17/18639 0.117647058823529 1.47565513419365 0.397796504265233 0.776553175847685 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/1486 17/18639 0.117647058823529 1.47565513419365 0.397796504265233 0.776553175847685 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/1486 17/18639 0.117647058823529 1.47565513419365 0.397796504265233 0.776553175847685 GO:0030548 acetylcholine receptor regulator activity 2/1486 17/18639 0.117647058823529 1.47565513419365 0.397796504265233 0.776553175847685 GO:0032977 membrane insertase activity 2/1486 17/18639 0.117647058823529 1.47565513419365 0.397796504265233 0.776553175847685 GO:0038191 neuropilin binding 2/1486 17/18639 0.117647058823529 1.47565513419365 0.397796504265233 0.776553175847685 GO:0005080 protein kinase C binding 5/1486 52/18639 0.0961538461538462 1.20606429236981 0.400721032651851 0.779596966419785 GO:0030159 signaling receptor complex adaptor activity 5/1486 52/18639 0.0961538461538462 1.20606429236981 0.400721032651851 0.779596966419785 GO:0004175 endopeptidase activity 34/1486 405/18639 0.0839506172839506 1.0529983550172 0.401997135856979 0.780688343217127 GO:0004536 DNA nuclease activity 6/1486 64/18639 0.09375 1.17591268506057 0.40267404805961 0.780688343217127 GO:0043130 ubiquitin binding 9/1486 100/18639 0.09 1.12887617765814 0.403332856828463 0.780688343217127 GO:0046982 protein heterodimerization activity 31/1486 369/18639 0.0840108401084011 1.05375373403801 0.407176844469359 0.785372283223641 GO:0004629 phospholipase C activity 3/1486 29/18639 0.103448275862069 1.29755882489442 0.410566771527595 0.785372283223641 GO:0005416 amino acid:monoatomic cation symporter activity 3/1486 29/18639 0.103448275862069 1.29755882489442 0.410566771527595 0.785372283223641 GO:0035250 UDP-galactosyltransferase activity 3/1486 29/18639 0.103448275862069 1.29755882489442 0.410566771527595 0.785372283223641 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 3/1486 29/18639 0.103448275862069 1.29755882489442 0.410566771527595 0.785372283223641 GO:0051861 glycolipid binding 3/1486 29/18639 0.103448275862069 1.29755882489442 0.410566771527595 0.785372283223641 GO:0106222 lncRNA binding 3/1486 29/18639 0.103448275862069 1.29755882489442 0.410566771527595 0.785372283223641 GO:0016877 ligase activity, forming carbon-sulfur bonds 4/1486 41/18639 0.0975609756097561 1.22371401372156 0.415200004148031 0.792608514817209 GO:0140296 general transcription initiation factor binding 5/1486 53/18639 0.0943396226415094 1.1833083623251 0.416908346332247 0.792608514817209 GO:1901505 carbohydrate derivative transmembrane transporter activity 5/1486 53/18639 0.0943396226415094 1.1833083623251 0.416908346332247 0.792608514817209 GO:0008083 growth factor activity 14/1486 162/18639 0.0864197530864197 1.08396889487064 0.417125847114836 0.792608514817209 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/1486 18/18639 0.111111111111111 1.39367429340511 0.426408985489085 0.7934315212467 GO:0008308 voltage-gated monoatomic anion channel activity 2/1486 18/18639 0.111111111111111 1.39367429340511 0.426408985489085 0.7934315212467 GO:0008409 5'-3' exonuclease activity 2/1486 18/18639 0.111111111111111 1.39367429340511 0.426408985489085 0.7934315212467 GO:0008525 phosphatidylcholine transporter activity 2/1486 18/18639 0.111111111111111 1.39367429340511 0.426408985489085 0.7934315212467 GO:0015373 monoatomic anion:sodium symporter activity 2/1486 18/18639 0.111111111111111 1.39367429340511 0.426408985489085 0.7934315212467 GO:0016854 racemase and epimerase activity 2/1486 18/18639 0.111111111111111 1.39367429340511 0.426408985489085 0.7934315212467 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/1486 18/18639 0.111111111111111 1.39367429340511 0.426408985489085 0.7934315212467 GO:0034185 apolipoprotein binding 2/1486 18/18639 0.111111111111111 1.39367429340511 0.426408985489085 0.7934315212467 GO:0070064 proline-rich region binding 2/1486 18/18639 0.111111111111111 1.39367429340511 0.426408985489085 0.7934315212467 GO:0099602 neurotransmitter receptor regulator activity 2/1486 18/18639 0.111111111111111 1.39367429340511 0.426408985489085 0.7934315212467 GO:1901611 phosphatidylglycerol binding 2/1486 18/18639 0.111111111111111 1.39367429340511 0.426408985489085 0.7934315212467 GO:0008238 exopeptidase activity 9/1486 102/18639 0.0882352941176471 1.10674135064524 0.426591028060835 0.7934315212467 GO:0015171 amino acid transmembrane transporter activity 9/1486 102/18639 0.0882352941176471 1.10674135064524 0.426591028060835 0.7934315212467 GO:0046943 carboxylic acid transmembrane transporter activity 16/1486 188/18639 0.0851063829787234 1.06749520345924 0.430557933204103 0.79856176431054 GO:0008235 metalloexopeptidase activity 6/1486 66/18639 0.0909090909090909 1.14027896733146 0.431785418988846 0.79856176431054 GO:0001965 G-protein alpha-subunit binding 3/1486 30/18639 0.1 1.2543068640646 0.432417141664284 0.79856176431054 GO:0015215 nucleotide transmembrane transporter activity 3/1486 30/18639 0.1 1.2543068640646 0.432417141664284 0.79856176431054 GO:0043175 RNA polymerase core enzyme binding 4/1486 42/18639 0.0952380952380952 1.19457796577581 0.433544915825337 0.79856176431054 GO:0051879 Hsp90 protein binding 4/1486 42/18639 0.0952380952380952 1.19457796577581 0.433544915825337 0.79856176431054 GO:0005342 organic acid transmembrane transporter activity 16/1486 189/18639 0.0846560846560847 1.06184708068961 0.439114203707805 0.807517585562501 GO:0042054 histone methyltransferase activity 6/1486 67/18639 0.0895522388059701 1.12325987826681 0.446257556915461 0.818295505866872 GO:0015294 solute:monoatomic cation symporter activity 10/1486 116/18639 0.0862068965517241 1.08129902074535 0.446628250247143 0.818295505866872 GO:0019902 phosphatase binding 16/1486 190/18639 0.0842105263157895 1.05625841184388 0.447667595735307 0.818295505866872 GO:0005319 lipid transporter activity 15/1486 178/18639 0.0842696629213483 1.05700016634658 0.45066586044788 0.818295505866872 GO:0008375 acetylglucosaminyltransferase activity 4/1486 43/18639 0.0930232558139535 1.16679708285079 0.451726608848609 0.818295505866872 GO:0048156 tau protein binding 4/1486 43/18639 0.0930232558139535 1.16679708285079 0.451726608848609 0.818295505866872 GO:0047499 calcium-independent phospholipase A2 activity 3/1486 31/18639 0.0967741935483871 1.21384535232058 0.453962559720116 0.818295505866872 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/1486 19/18639 0.105263157894737 1.32032301480485 0.454290149491766 0.818295505866872 GO:0015245 fatty acid transmembrane transporter activity 2/1486 19/18639 0.105263157894737 1.32032301480485 0.454290149491766 0.818295505866872 GO:0016918 retinal binding 2/1486 19/18639 0.105263157894737 1.32032301480485 0.454290149491766 0.818295505866872 GO:0042800 histone H3K4 methyltransferase activity 2/1486 19/18639 0.105263157894737 1.32032301480485 0.454290149491766 0.818295505866872 GO:0046527 glucosyltransferase activity 2/1486 19/18639 0.105263157894737 1.32032301480485 0.454290149491766 0.818295505866872 GO:0070003 threonine-type peptidase activity 2/1486 19/18639 0.105263157894737 1.32032301480485 0.454290149491766 0.818295505866872 GO:1990782 protein tyrosine kinase binding 10/1486 117/18639 0.0854700854700855 1.07205714877316 0.45755969650994 0.822886887266695 GO:0015101 organic cation transmembrane transporter activity 7/1486 81/18639 0.0864197530864197 1.08396889487064 0.469927342239519 0.833318361548961 GO:0033192 calmodulin-dependent protein phosphatase activity 7/1486 81/18639 0.0864197530864197 1.08396889487064 0.469927342239519 0.833318361548961 GO:0140791 histone H2AXS140 phosphatase activity 7/1486 81/18639 0.0864197530864197 1.08396889487064 0.469927342239519 0.833318361548961 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 7/1486 81/18639 0.0864197530864197 1.08396889487064 0.469927342239519 0.833318361548961 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 7/1486 81/18639 0.0864197530864197 1.08396889487064 0.469927342239519 0.833318361548961 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 7/1486 81/18639 0.0864197530864197 1.08396889487064 0.469927342239519 0.833318361548961 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 7/1486 81/18639 0.0864197530864197 1.08396889487064 0.469927342239519 0.833318361548961 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 7/1486 81/18639 0.0864197530864197 1.08396889487064 0.469927342239519 0.833318361548961 GO:1990439 MAP kinase serine/threonine phosphatase activity 7/1486 81/18639 0.0864197530864197 1.08396889487064 0.469927342239519 0.833318361548961 GO:0008013 beta-catenin binding 9/1486 106/18639 0.0849056603773585 1.06497752609259 0.472843492292108 0.836102973165143 GO:0002039 p53 binding 6/1486 69/18639 0.0869565217391304 1.09070162092574 0.474947699348593 0.836102973165143 GO:0042910 xenobiotic transmembrane transporter activity 3/1486 32/18639 0.09375 1.17591268506057 0.475158344644639 0.836102973165143 GO:0047498 calcium-dependent phospholipase A2 activity 3/1486 32/18639 0.09375 1.17591268506057 0.475158344644639 0.836102973165143 GO:0051059 NF-kappaB binding 3/1486 32/18639 0.09375 1.17591268506057 0.475158344644639 0.836102973165143 GO:0015932 nucleobase-containing compound transmembrane transporter activity 5/1486 57/18639 0.087719298245614 1.10026917900404 0.480687401213161 0.838002922956532 GO:0016504 peptidase activator activity 5/1486 57/18639 0.087719298245614 1.10026917900404 0.480687401213161 0.838002922956532 GO:0000339 RNA cap binding 2/1486 20/18639 0.1 1.2543068640646 0.481374708808656 0.838002922956532 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 2/1486 20/18639 0.1 1.2543068640646 0.481374708808656 0.838002922956532 GO:0005326 neurotransmitter transmembrane transporter activity 2/1486 20/18639 0.1 1.2543068640646 0.481374708808656 0.838002922956532 GO:0015095 magnesium ion transmembrane transporter activity 2/1486 20/18639 0.1 1.2543068640646 0.481374708808656 0.838002922956532 GO:0016408 C-acyltransferase activity 2/1486 20/18639 0.1 1.2543068640646 0.481374708808656 0.838002922956532 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 7/1486 82/18639 0.0853658536585366 1.07074976200637 0.483026340141767 0.838322310701973 GO:0033549 MAP kinase phosphatase activity 7/1486 82/18639 0.0853658536585366 1.07074976200637 0.483026340141767 0.838322310701973 GO:0004715 non-membrane spanning protein tyrosine kinase activity 4/1486 45/18639 0.0888888888888889 1.11493943472409 0.487479614812213 0.843487454720527 GO:0046915 transition metal ion transmembrane transporter activity 4/1486 45/18639 0.0888888888888889 1.11493943472409 0.487479614812213 0.843487454720527 GO:0032182 ubiquitin-like protein binding 10/1486 120/18639 0.0833333333333333 1.04525572005384 0.490127238171417 0.845731252354267 GO:0008194 UDP-glycosyltransferase activity 12/1486 145/18639 0.0827586206896552 1.03804705991553 0.49025752106701 0.845731252354267 GO:0140416 transcription regulator inhibitor activity 3/1486 33/18639 0.0909090909090909 1.14027896733146 0.495965230715331 0.853117089248297 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 7/1486 83/18639 0.0843373493975904 1.05784916246412 0.496033053643493 0.853117089248297 GO:0001846 opsonin binding 2/1486 21/18639 0.0952380952380952 1.19457796577581 0.50761241866898 0.867469676811879 GO:0009975 cyclase activity 2/1486 21/18639 0.0952380952380952 1.19457796577581 0.50761241866898 0.867469676811879 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/1486 21/18639 0.0952380952380952 1.19457796577581 0.50761241866898 0.867469676811879 GO:0051428 peptide hormone receptor binding 2/1486 21/18639 0.0952380952380952 1.19457796577581 0.50761241866898 0.867469676811879 GO:0004527 exonuclease activity 7/1486 84/18639 0.0833333333333333 1.04525572005384 0.508935799880875 0.867469676811879 GO:0017018 myosin phosphatase activity 7/1486 84/18639 0.0833333333333333 1.04525572005384 0.508935799880875 0.867469676811879 GO:0015078 proton transmembrane transporter activity 15/1486 185/18639 0.0810810810810811 1.01700556545779 0.512059787816528 0.871493707431408 GO:0015291 secondary active transmembrane transporter activity 23/1486 287/18639 0.0801393728222996 1.00519365412843 0.521464696636314 0.884867830409926 GO:0001784 phosphotyrosine residue binding 4/1486 47/18639 0.0851063829787234 1.06749520345924 0.52224248484789 0.884867830409926 GO:0043495 protein-membrane adaptor activity 4/1486 47/18639 0.0851063829787234 1.06749520345924 0.52224248484789 0.884867830409926 GO:0042626 ATPase-coupled transmembrane transporter activity 8/1486 98/18639 0.0816326530612245 1.02392397066498 0.525777967361334 0.885369943939491 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 5/1486 60/18639 0.0833333333333333 1.04525572005384 0.526908671955936 0.885369943939491 GO:0004521 RNA endonuclease activity 6/1486 73/18639 0.0821917808219178 1.03093714854625 0.530876756323572 0.885369943939491 GO:0005243 gap junction channel activity 2/1486 22/18639 0.0909090909090909 1.14027896733146 0.532966096120057 0.885369943939491 GO:0015377 chloride:monoatomic cation symporter activity 2/1486 22/18639 0.0909090909090909 1.14027896733146 0.532966096120057 0.885369943939491 GO:0061133 endopeptidase activator activity 2/1486 22/18639 0.0909090909090909 1.14027896733146 0.532966096120057 0.885369943939491 GO:0140784 metal ion sensor activity 2/1486 22/18639 0.0909090909090909 1.14027896733146 0.532966096120057 0.885369943939491 GO:0004721 phosphoprotein phosphatase activity 14/1486 175/18639 0.08 1.00344549125168 0.535134356282172 0.885369943939491 GO:0004623 phospholipase A2 activity 3/1486 35/18639 0.0857142857142857 1.07512016919823 0.536280576492069 0.885369943939491 GO:0005343 organic acid:sodium symporter activity 3/1486 35/18639 0.0857142857142857 1.07512016919823 0.536280576492069 0.885369943939491 GO:0043015 gamma-tubulin binding 3/1486 35/18639 0.0857142857142857 1.07512016919823 0.536280576492069 0.885369943939491 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4/1486 48/18639 0.0833333333333333 1.04525572005384 0.539195584288999 0.885369943939491 GO:0051020 GTPase binding 25/1486 315/18639 0.0793650793650794 0.99548163814651 0.540021277874631 0.885369943939491 GO:0015026 coreceptor activity 5/1486 61/18639 0.0819672131147541 1.02812038038082 0.541911799146084 0.885369943939491 GO:0016836 hydro-lyase activity 5/1486 61/18639 0.0819672131147541 1.02812038038082 0.541911799146084 0.885369943939491 GO:0008081 phosphoric diester hydrolase activity 7/1486 87/18639 0.0804597701149425 1.00921241936232 0.546912323429588 0.885369943939491 GO:0001222 transcription corepressor binding 4/1486 49/18639 0.0816326530612245 1.02392397066498 0.555837361684538 0.885369943939491 GO:0060590 ATPase regulator activity 4/1486 49/18639 0.0816326530612245 1.02392397066498 0.555837361684538 0.885369943939491 GO:0015179 L-amino acid transmembrane transporter activity 5/1486 62/18639 0.0806451612903226 1.01153779360049 0.556687827762998 0.885369943939491 GO:0005212 structural constituent of eye lens 2/1486 23/18639 0.0869565217391304 1.09070162092574 0.557409859057987 0.885369943939491 GO:0008171 O-methyltransferase activity 2/1486 23/18639 0.0869565217391304 1.09070162092574 0.557409859057987 0.885369943939491 GO:0016849 phosphorus-oxygen lyase activity 2/1486 23/18639 0.0869565217391304 1.09070162092574 0.557409859057987 0.885369943939491 GO:0031681 G-protein beta-subunit binding 2/1486 23/18639 0.0869565217391304 1.09070162092574 0.557409859057987 0.885369943939491 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/1486 23/18639 0.0869565217391304 1.09070162092574 0.557409859057987 0.885369943939491 GO:0140103 catalytic activity, acting on a glycoprotein 2/1486 23/18639 0.0869565217391304 1.09070162092574 0.557409859057987 0.885369943939491 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/1486 23/18639 0.0869565217391304 1.09070162092574 0.557409859057987 0.885369943939491 GO:0004519 endonuclease activity 10/1486 127/18639 0.078740157480315 0.987643200050868 0.563891350210089 0.885369943939491 GO:0042826 histone deacetylase binding 10/1486 127/18639 0.078740157480315 0.987643200050868 0.563891350210089 0.885369943939491 GO:0004090 carbonyl reductase (NADPH) activity 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0004935 adrenergic receptor activity 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0004955 prostaglandin receptor activity 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0005031 tumor necrosis factor receptor activity 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0005381 iron ion transmembrane transporter activity 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0008239 dipeptidyl-peptidase activity 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0016427 tRNA (cytidine) methyltransferase activity 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0019911 structural constituent of myelin sheath 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0031434 mitogen-activated protein kinase kinase binding 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0032052 bile acid binding 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0033204 ribonuclease P RNA binding 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0042975 peroxisome proliferator activated receptor binding 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0043121 neurotrophin binding 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0071723 lipopeptide binding 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0140135 mechanosensitive monoatomic cation channel activity 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0140999 histone H3K4 trimethyltransferase activity 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0141109 transporter activator activity 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:1990757 ubiquitin ligase activator activity 1/1486 10/18639 0.1 1.2543068640646 0.564403957257399 0.885369943939491 GO:0017022 myosin binding 6/1486 76/18639 0.0789473684210526 0.990242261103634 0.571132809091313 0.889665283436453 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 7/1486 89/18639 0.0786516853932584 0.986533488590137 0.571522874428887 0.889665283436453 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 7/1486 89/18639 0.0786516853932584 0.986533488590137 0.571522874428887 0.889665283436453 GO:0031490 chromatin DNA binding 10/1486 128/18639 0.078125 0.979927237550471 0.574082143206713 0.889665283436453 GO:0023023 MHC protein complex binding 3/1486 37/18639 0.0810810810810811 1.01700556545779 0.574691563865373 0.889665283436453 GO:0015149 hexose transmembrane transporter activity 2/1486 24/18639 0.0833333333333333 1.04525572005384 0.580927562726899 0.889665283436453 GO:0035035 histone acetyltransferase binding 2/1486 24/18639 0.0833333333333333 1.04525572005384 0.580927562726899 0.889665283436453 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/1486 24/18639 0.0833333333333333 1.04525572005384 0.580927562726899 0.889665283436453 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/1486 24/18639 0.0833333333333333 1.04525572005384 0.580927562726899 0.889665283436453 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/1486 24/18639 0.0833333333333333 1.04525572005384 0.580927562726899 0.889665283436453 GO:0055056 D-glucose transmembrane transporter activity 2/1486 24/18639 0.0833333333333333 1.04525572005384 0.580927562726899 0.889665283436453 GO:0070300 phosphatidic acid binding 2/1486 24/18639 0.0833333333333333 1.04525572005384 0.580927562726899 0.889665283436453 GO:0070840 dynein complex binding 2/1486 24/18639 0.0833333333333333 1.04525572005384 0.580927562726899 0.889665283436453 GO:0140793 histone H2AXY142 phosphatase activity 7/1486 90/18639 0.0777777777777778 0.97557200538358 0.583589971756422 0.889665283436453 GO:0016247 channel regulator activity 13/1486 168/18639 0.0773809523809524 0.970594597192848 0.586320424486056 0.889665283436453 GO:0106310 protein serine kinase activity 28/1486 361/18639 0.0775623268698061 0.972869589856202 0.589488083160285 0.889665283436453 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 27/1486 349/18639 0.0773638968481375 0.970380668474048 0.594359726544076 0.889665283436453 GO:0004016 adenylate cyclase activity 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0004954 prostanoid receptor activity 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0008271 secondary active sulfate transmembrane transporter activity 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0008526 phosphatidylinositol transfer activity 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0015173 aromatic amino acid transmembrane transporter activity 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0016594 glycine binding 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0019206 nucleoside kinase activity 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0032050 clathrin heavy chain binding 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0032404 mismatch repair complex binding 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0035252 UDP-xylosyltransferase activity 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0042285 xylosyltransferase activity 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0042608 T cell receptor binding 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0070697 activin receptor binding 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0140537 transcription regulator activator activity 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0180030 inositol phosphate kinase activity 1/1486 11/18639 0.0909090909090909 1.14027896733146 0.599150627476708 0.889665283436453 GO:0120013 lipid transfer activity 5/1486 65/18639 0.0769230769230769 0.964851433895849 0.599528877343883 0.889665283436453 GO:0000030 mannosyltransferase activity 2/1486 25/18639 0.08 1.00344549125168 0.603511413425263 0.889665283436453 GO:0001848 complement binding 2/1486 25/18639 0.08 1.00344549125168 0.603511413425263 0.889665283436453 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/1486 25/18639 0.08 1.00344549125168 0.603511413425263 0.889665283436453 GO:0015645 fatty acid ligase activity 2/1486 25/18639 0.08 1.00344549125168 0.603511413425263 0.889665283436453 GO:0015662 P-type ion transporter activity 2/1486 25/18639 0.08 1.00344549125168 0.603511413425263 0.889665283436453 GO:0017025 TBP-class protein binding 2/1486 25/18639 0.08 1.00344549125168 0.603511413425263 0.889665283436453 GO:0120020 cholesterol transfer activity 2/1486 25/18639 0.08 1.00344549125168 0.603511413425263 0.889665283436453 GO:0120515 fatty acid-CoA ligase activity 2/1486 25/18639 0.08 1.00344549125168 0.603511413425263 0.889665283436453 GO:0140358 P-type transmembrane transporter activity 2/1486 25/18639 0.08 1.00344549125168 0.603511413425263 0.889665283436453 GO:0141108 transporter regulator activity 13/1486 170/18639 0.0764705882352941 0.959175837225873 0.603757088146454 0.889665283436453 GO:0008186 ATP-dependent activity, acting on RNA 6/1486 79/18639 0.0759493670886076 0.952638124606028 0.609616695448854 0.893025317521555 GO:0005544 calcium-dependent phospholipid binding 4/1486 53/18639 0.0754716981132075 0.946646689860078 0.618991191173309 0.893025317521555 GO:0005160 transforming growth factor beta receptor binding 2/1486 26/18639 0.0769230769230769 0.964851433895849 0.625160741130159 0.893025317521555 GO:0015145 monosaccharide transmembrane transporter activity 2/1486 26/18639 0.0769230769230769 0.964851433895849 0.625160741130159 0.893025317521555 GO:0030507 spectrin binding 2/1486 26/18639 0.0769230769230769 0.964851433895849 0.625160741130159 0.893025317521555 GO:0120014 phospholipid transfer activity 2/1486 26/18639 0.0769230769230769 0.964851433895849 0.625160741130159 0.893025317521555 GO:0099106 ion channel regulator activity 12/1486 160/18639 0.075 0.940730148048452 0.630146650509864 0.893025317521555 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0003720 telomerase activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0003995 acyl-CoA dehydrogenase activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0004000 adenosine deaminase activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0004300 enoyl-CoA hydratase activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0004526 ribonuclease P activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0004875 complement receptor activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0005025 transforming growth factor beta receptor activity, type I 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0005026 transforming growth factor beta receptor activity, type II 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0005165 neurotrophin receptor binding 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0008603 cAMP-dependent protein kinase regulator activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0016273 arginine N-methyltransferase activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0016274 protein-arginine N-methyltransferase activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0016361 activin receptor activity, type I 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0016362 activin receptor activity, type II 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0017002 activin receptor activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0035259 nuclear glucocorticoid receptor binding 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0097677 STAT family protein binding 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:1990817 poly(A) RNA polymerase activity 1/1486 12/18639 0.0833333333333333 1.04525572005384 0.631127338211602 0.893025317521555 GO:0005543 phospholipid binding 38/1486 497/18639 0.0764587525150905 0.959027380974948 0.63184278157392 0.893025317521555 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 4/1486 54/18639 0.0740740740740741 0.92911619560341 0.633868733315401 0.894781326880331 GO:0005548 phospholipid transporter activity 5/1486 68/18639 0.0735294117647059 0.922284458871032 0.639930080316057 0.902222409532021 GO:0008276 protein methyltransferase activity 7/1486 95/18639 0.0736842105263158 0.924226110363392 0.641261936460532 0.902810286905285 GO:0008137 NADH dehydrogenase (ubiquinone) activity 3/1486 41/18639 0.0731707317073171 0.917785510291173 0.645259793341921 0.902810286905285 GO:0017080 sodium channel regulator activity 3/1486 41/18639 0.0731707317073171 0.917785510291173 0.645259793341921 0.902810286905285 GO:0042287 MHC protein binding 3/1486 41/18639 0.0731707317073171 0.917785510291173 0.645259793341921 0.902810286905285 GO:0140828 metal cation:monoatomic cation antiporter activity 3/1486 41/18639 0.0731707317073171 0.917785510291173 0.645259793341921 0.902810286905285 GO:0005104 fibroblast growth factor receptor binding 2/1486 27/18639 0.0740740740740741 0.92911619560341 0.645880914537318 0.902810286905285 GO:0016405 CoA-ligase activity 2/1486 27/18639 0.0740740740740741 0.92911619560341 0.645880914537318 0.902810286905285 GO:0008080 N-acetyltransferase activity 5/1486 69/18639 0.072463768115942 0.908918017438118 0.652819328829139 0.90286138017725 GO:0016279 protein-lysine N-methyltransferase activity 5/1486 69/18639 0.072463768115942 0.908918017438118 0.652819328829139 0.90286138017725 GO:0003964 RNA-directed DNA polymerase activity 1/1486 13/18639 0.0769230769230769 0.964851433895849 0.660554770187634 0.90286138017725 GO:0004465 lipoprotein lipase activity 1/1486 13/18639 0.0769230769230769 0.964851433895849 0.660554770187634 0.90286138017725 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/1486 13/18639 0.0769230769230769 0.964851433895849 0.660554770187634 0.90286138017725 GO:0005035 death receptor activity 1/1486 13/18639 0.0769230769230769 0.964851433895849 0.660554770187634 0.90286138017725 GO:0008253 5'-nucleotidase activity 1/1486 13/18639 0.0769230769230769 0.964851433895849 0.660554770187634 0.90286138017725 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/1486 13/18639 0.0769230769230769 0.964851433895849 0.660554770187634 0.90286138017725 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1486 13/18639 0.0769230769230769 0.964851433895849 0.660554770187634 0.90286138017725 GO:0030955 potassium ion binding 1/1486 13/18639 0.0769230769230769 0.964851433895849 0.660554770187634 0.90286138017725 GO:0031432 titin binding 1/1486 13/18639 0.0769230769230769 0.964851433895849 0.660554770187634 0.90286138017725 GO:0046974 histone H3K9 methyltransferase activity 1/1486 13/18639 0.0769230769230769 0.964851433895849 0.660554770187634 0.90286138017725 GO:0046975 histone H3K36 methyltransferase activity 1/1486 13/18639 0.0769230769230769 0.964851433895849 0.660554770187634 0.90286138017725 GO:0070123 transforming growth factor beta receptor activity, type III 1/1486 13/18639 0.0769230769230769 0.964851433895849 0.660554770187634 0.90286138017725 GO:0089720 caspase binding 1/1486 13/18639 0.0769230769230769 0.964851433895849 0.660554770187634 0.90286138017725 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/1486 13/18639 0.0769230769230769 0.964851433895849 0.660554770187634 0.90286138017725 GO:0140852 histone ubiquitin ligase activity 1/1486 13/18639 0.0769230769230769 0.964851433895849 0.660554770187634 0.90286138017725 GO:0019894 kinesin binding 3/1486 42/18639 0.0714285714285714 0.895933474331859 0.661545553150889 0.90286138017725 GO:0170055 lipid transmembrane transporter activity 4/1486 56/18639 0.0714285714285714 0.895933474331859 0.662475425673477 0.90286138017725 GO:0016278 lysine N-methyltransferase activity 5/1486 70/18639 0.0714285714285714 0.895933474331859 0.665410556517276 0.90286138017725 GO:0019789 SUMO transferase activity 2/1486 28/18639 0.0714285714285714 0.895933474331859 0.665682383633314 0.90286138017725 GO:0046966 nuclear thyroid hormone receptor binding 2/1486 28/18639 0.0714285714285714 0.895933474331859 0.665682383633314 0.90286138017725 GO:0051019 mitogen-activated protein kinase binding 2/1486 28/18639 0.0714285714285714 0.895933474331859 0.665682383633314 0.90286138017725 GO:0051119 sugar transmembrane transporter activity 2/1486 28/18639 0.0714285714285714 0.895933474331859 0.665682383633314 0.90286138017725 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/1486 28/18639 0.0714285714285714 0.895933474331859 0.665682383633314 0.90286138017725 GO:1902936 phosphatidylinositol bisphosphate binding 8/1486 111/18639 0.0720720720720721 0.904004947073588 0.668192388042378 0.905190637181963 GO:0004725 protein tyrosine phosphatase activity 7/1486 98/18639 0.0714285714285714 0.895933474331859 0.673537259205569 0.910271656819834 GO:0008170 N-methyltransferase activity 7/1486 98/18639 0.0714285714285714 0.895933474331859 0.673537259205569 0.910271656819834 GO:0016417 S-acyltransferase activity 2/1486 29/18639 0.0689655172413793 0.865039216596278 0.684579836381885 0.912438587470773 GO:0016791 phosphatase activity 20/1486 273/18639 0.0732600732600733 0.918906127519856 0.686756859604913 0.912438587470773 GO:0005313 L-glutamate transmembrane transporter activity 1/1486 14/18639 0.0714285714285714 0.895933474331859 0.687636033556107 0.912438587470773 GO:0008174 mRNA methyltransferase activity 1/1486 14/18639 0.0714285714285714 0.895933474331859 0.687636033556107 0.912438587470773 GO:0008392 arachidonate epoxygenase activity 1/1486 14/18639 0.0714285714285714 0.895933474331859 0.687636033556107 0.912438587470773 GO:0008494 translation activator activity 1/1486 14/18639 0.0714285714285714 0.895933474331859 0.687636033556107 0.912438587470773 GO:0030983 mismatched DNA binding 1/1486 14/18639 0.0714285714285714 0.895933474331859 0.687636033556107 0.912438587470773 GO:0032454 histone H3K9 demethylase activity 1/1486 14/18639 0.0714285714285714 0.895933474331859 0.687636033556107 0.912438587470773 GO:0034236 protein kinase A catalytic subunit binding 1/1486 14/18639 0.0714285714285714 0.895933474331859 0.687636033556107 0.912438587470773 GO:0046030 inositol trisphosphate phosphatase activity 1/1486 14/18639 0.0714285714285714 0.895933474331859 0.687636033556107 0.912438587470773 GO:0070742 C2H2 zinc finger domain binding 1/1486 14/18639 0.0714285714285714 0.895933474331859 0.687636033556107 0.912438587470773 GO:0071933 Arp2/3 complex binding 1/1486 14/18639 0.0714285714285714 0.895933474331859 0.687636033556107 0.912438587470773 GO:0098821 BMP receptor activity 1/1486 14/18639 0.0714285714285714 0.895933474331859 0.687636033556107 0.912438587470773 GO:1901474 azole transmembrane transporter activity 1/1486 14/18639 0.0714285714285714 0.895933474331859 0.687636033556107 0.912438587470773 GO:1901612 cardiolipin binding 1/1486 14/18639 0.0714285714285714 0.895933474331859 0.687636033556107 0.912438587470773 GO:0016874 ligase activity 12/1486 167/18639 0.0718562874251497 0.901298345435643 0.688247734881201 0.912438587470773 GO:0008408 3'-5' exonuclease activity 4/1486 58/18639 0.0689655172413793 0.865039216596278 0.689522330111451 0.912438587470773 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 4/1486 58/18639 0.0689655172413793 0.865039216596278 0.689522330111451 0.912438587470773 GO:0003954 NADH dehydrogenase activity 3/1486 44/18639 0.0681818181818182 0.855209225498593 0.692469854517173 0.915278441965985 GO:0003730 mRNA 3'-UTR binding 19/1486 262/18639 0.0725190839694656 0.909611847985781 0.700617015586332 0.919500820416606 GO:0042277 peptide binding 18/1486 249/18639 0.072289156626506 0.906727853540677 0.702328650157586 0.919500820416606 GO:0015459 potassium channel regulator activity 4/1486 59/18639 0.0677966101694915 0.850377534959053 0.702455383648265 0.919500820416606 GO:0048019 receptor antagonist activity 2/1486 30/18639 0.0666666666666667 0.836204576043069 0.702591457433142 0.919500820416606 GO:0008009 chemokine activity 3/1486 45/18639 0.0666666666666667 0.836204576043069 0.707112014496098 0.919500820416606 GO:0051539 4 iron, 4 sulfur cluster binding 3/1486 45/18639 0.0666666666666667 0.836204576043069 0.707112014496098 0.919500820416606 GO:0000774 adenyl-nucleotide exchange factor activity 1/1486 15/18639 0.0666666666666667 0.836204576043069 0.712558065992919 0.919500820416606 GO:0004089 carbonate dehydratase activity 1/1486 15/18639 0.0666666666666667 0.836204576043069 0.712558065992919 0.919500820416606 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1486 15/18639 0.0666666666666667 0.836204576043069 0.712558065992919 0.919500820416606 GO:0004953 icosanoid receptor activity 1/1486 15/18639 0.0666666666666667 0.836204576043069 0.712558065992919 0.919500820416606 GO:0008242 omega peptidase activity 1/1486 15/18639 0.0666666666666667 0.836204576043069 0.712558065992919 0.919500820416606 GO:0008252 nucleotidase activity 1/1486 15/18639 0.0666666666666667 0.836204576043069 0.712558065992919 0.919500820416606 GO:0015116 sulfate transmembrane transporter activity 1/1486 15/18639 0.0666666666666667 0.836204576043069 0.712558065992919 0.919500820416606 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1486 15/18639 0.0666666666666667 0.836204576043069 0.712558065992919 0.919500820416606 GO:0030553 cGMP binding 1/1486 15/18639 0.0666666666666667 0.836204576043069 0.712558065992919 0.919500820416606 GO:0031005 filamin binding 1/1486 15/18639 0.0666666666666667 0.836204576043069 0.712558065992919 0.919500820416606 GO:0034483 heparan sulfate sulfotransferase activity 1/1486 15/18639 0.0666666666666667 0.836204576043069 0.712558065992919 0.919500820416606 GO:0042809 nuclear vitamin D receptor binding 1/1486 15/18639 0.0666666666666667 0.836204576043069 0.712558065992919 0.919500820416606 GO:0050700 CARD domain binding 1/1486 15/18639 0.0666666666666667 0.836204576043069 0.712558065992919 0.919500820416606 GO:0061578 K63-linked deubiquitinase activity 1/1486 15/18639 0.0666666666666667 0.836204576043069 0.712558065992919 0.919500820416606 GO:0004197 cysteine-type endopeptidase activity 6/1486 88/18639 0.0681818181818182 0.855209225498593 0.712572877468211 0.919500820416606 GO:0005164 tumor necrosis factor receptor binding 2/1486 31/18639 0.0645161290322581 0.809230234880389 0.719738277965076 0.925609361977609 GO:0005310 dicarboxylic acid transmembrane transporter activity 2/1486 31/18639 0.0645161290322581 0.809230234880389 0.719738277965076 0.925609361977609 GO:0016878 acid-thiol ligase activity 2/1486 31/18639 0.0645161290322581 0.809230234880389 0.719738277965076 0.925609361977609 GO:1901981 phosphatidylinositol phosphate binding 13/1486 185/18639 0.0702702702702703 0.881404823396748 0.722257732176546 0.927804645833088 GO:0004722 protein serine/threonine phosphatase activity 7/1486 103/18639 0.0679611650485437 0.852441558102157 0.723135855294465 0.927888928928404 GO:0019905 syntaxin binding 4/1486 61/18639 0.0655737704918033 0.822496304304658 0.727140584331666 0.930854705455421 GO:0140359 ABC-type transporter activity 3/1486 47/18639 0.0638297872340425 0.800621402594427 0.734779251408312 0.930854705455421 GO:0000062 fatty-acyl-CoA binding 1/1486 16/18639 0.0625 0.783941790040377 0.735492919619129 0.930854705455421 GO:0005149 interleukin-1 receptor binding 1/1486 16/18639 0.0625 0.783941790040377 0.735492919619129 0.930854705455421 GO:0008296 3'-5'-DNA exonuclease activity 1/1486 16/18639 0.0625 0.783941790040377 0.735492919619129 0.930854705455421 GO:0008391 arachidonate monooxygenase activity 1/1486 16/18639 0.0625 0.783941790040377 0.735492919619129 0.930854705455421 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/1486 16/18639 0.0625 0.783941790040377 0.735492919619129 0.930854705455421 GO:0022858 alanine transmembrane transporter activity 1/1486 16/18639 0.0625 0.783941790040377 0.735492919619129 0.930854705455421 GO:0030275 LRR domain binding 1/1486 16/18639 0.0625 0.783941790040377 0.735492919619129 0.930854705455421 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/1486 16/18639 0.0625 0.783941790040377 0.735492919619129 0.930854705455421 GO:0034450 ubiquitin-ubiquitin ligase activity 1/1486 16/18639 0.0625 0.783941790040377 0.735492919619129 0.930854705455421 GO:0140328 floppase activity 1/1486 16/18639 0.0625 0.783941790040377 0.735492919619129 0.930854705455421 GO:0015106 bicarbonate transmembrane transporter activity 2/1486 32/18639 0.0625 0.783941790040377 0.736043606853104 0.930854705455421 GO:0016741 transferase activity, transferring one-carbon groups 15/1486 215/18639 0.0697674418604651 0.875097812138095 0.741925582100727 0.937255547299812 GO:0042578 phosphoric ester hydrolase activity 26/1486 363/18639 0.0716253443526171 0.898401610624785 0.744939081848068 0.938965362332101 GO:0003724 RNA helicase activity 5/1486 77/18639 0.0649350649350649 0.814484976665326 0.744981573816849 0.938965362332101 GO:0140693 molecular condensate scaffold activity 3/1486 48/18639 0.0625 0.783941790040377 0.7478181625496 0.938965362332101 GO:0004497 monooxygenase activity 7/1486 106/18639 0.0660377358490566 0.828315853627568 0.750302967355235 0.938965362332101 GO:0071889 14-3-3 protein binding 2/1486 33/18639 0.0606060606060606 0.760185978220972 0.751532534345864 0.938965362332101 GO:0052689 carboxylic ester hydrolase activity 6/1486 92/18639 0.0652173913043478 0.818026215694306 0.751828556112158 0.938965362332101 GO:0004549 tRNA-specific ribonuclease activity 1/1486 17/18639 0.0588235294117647 0.737827567096825 0.756598945578747 0.938965362332101 GO:0015278 intracellularly gated calcium channel activity 1/1486 17/18639 0.0588235294117647 0.737827567096825 0.756598945578747 0.938965362332101 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/1486 17/18639 0.0588235294117647 0.737827567096825 0.756598945578747 0.938965362332101 GO:0031489 myosin V binding 1/1486 17/18639 0.0588235294117647 0.737827567096825 0.756598945578747 0.938965362332101 GO:0032183 SUMO binding 1/1486 17/18639 0.0588235294117647 0.737827567096825 0.756598945578747 0.938965362332101 GO:0036041 long-chain fatty acid binding 1/1486 17/18639 0.0588235294117647 0.737827567096825 0.756598945578747 0.938965362332101 GO:0045125 bioactive lipid receptor activity 1/1486 17/18639 0.0588235294117647 0.737827567096825 0.756598945578747 0.938965362332101 GO:0045236 CXCR chemokine receptor binding 1/1486 17/18639 0.0588235294117647 0.737827567096825 0.756598945578747 0.938965362332101 GO:0048038 quinone binding 1/1486 17/18639 0.0588235294117647 0.737827567096825 0.756598945578747 0.938965362332101 GO:1901567 fatty acid derivative binding 1/1486 17/18639 0.0588235294117647 0.737827567096825 0.756598945578747 0.938965362332101 GO:0004540 RNA nuclease activity 8/1486 121/18639 0.0661157024793388 0.829293794422878 0.758075154724217 0.938965362332101 GO:0015297 antiporter activity 9/1486 135/18639 0.0666666666666667 0.836204576043069 0.758078865210331 0.938965362332101 GO:0035254 glutamate receptor binding 3/1486 49/18639 0.0612244897959184 0.767942977998736 0.760338649562539 0.940744027952784 GO:0015370 solute:sodium symporter activity 5/1486 79/18639 0.0632911392405063 0.793865103838356 0.76494839071019 0.941912134938913 GO:0016779 nucleotidyltransferase activity 9/1486 136/18639 0.0661764705882353 0.830056012983928 0.765630539230336 0.941912134938913 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 8/1486 122/18639 0.0655737704918033 0.822496304304658 0.766025514549908 0.941912134938913 GO:0015020 glucuronosyltransferase activity 2/1486 34/18639 0.0588235294117647 0.737827567096825 0.766231500313704 0.941912134938913 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/1486 34/18639 0.0588235294117647 0.737827567096825 0.766231500313704 0.941912134938913 GO:0051427 hormone receptor binding 2/1486 34/18639 0.0588235294117647 0.737827567096825 0.766231500313704 0.941912134938913 GO:0016410 N-acyltransferase activity 6/1486 94/18639 0.0638297872340425 0.800621402594427 0.769931594340842 0.944794234534566 GO:0035402 histone H3T11 kinase activity 17/1486 247/18639 0.0688259109311741 0.863288125064706 0.770653432993037 0.944794234534566 GO:0015605 organophosphate ester transmembrane transporter activity 3/1486 50/18639 0.06 0.752584118438762 0.772350610460284 0.944794234534566 GO:0030695 GTPase regulator activity 35/1486 489/18639 0.0715746421267894 0.897765649125994 0.773196997087846 0.944794234534566 GO:0004620 phospholipase activity 7/1486 109/18639 0.0642201834862385 0.805518169582773 0.775515969628674 0.944794234534566 GO:0015172 acidic amino acid transmembrane transporter activity 1/1486 18/18639 0.0555555555555556 0.696837146702557 0.776021884407551 0.944794234534566 GO:0017128 phospholipid scramblase activity 1/1486 18/18639 0.0555555555555556 0.696837146702557 0.776021884407551 0.944794234534566 GO:0070628 proteasome binding 1/1486 18/18639 0.0555555555555556 0.696837146702557 0.776021884407551 0.944794234534566 GO:1990381 ubiquitin-specific protease binding 1/1486 18/18639 0.0555555555555556 0.696837146702557 0.776021884407551 0.944794234534566 GO:0060589 nucleoside-triphosphatase regulator activity 35/1486 490/18639 0.0714285714285714 0.895933474331859 0.777152193031488 0.9451627310351 GO:0000175 3'-5'-RNA exonuclease activity 2/1486 35/18639 0.0571428571428571 0.716746779465487 0.780167919939257 0.946813777439566 GO:0034061 DNA polymerase activity 2/1486 35/18639 0.0571428571428571 0.716746779465487 0.780167919939257 0.946813777439566 GO:0030971 receptor tyrosine kinase binding 5/1486 81/18639 0.0617283950617284 0.774263496336175 0.783707743016034 0.950100045142581 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 11/1486 167/18639 0.0658682634730539 0.826190149982673 0.78643815353148 0.95239912124385 GO:0004518 nuclease activity 14/1486 209/18639 0.0669856459330144 0.840205554875811 0.78829325466223 0.953342884516617 GO:0004190 aspartic-type endopeptidase activity 2/1486 36/18639 0.0555555555555556 0.696837146702557 0.793369860444828 0.953342884516617 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/1486 36/18639 0.0555555555555556 0.696837146702557 0.793369860444828 0.953342884516617 GO:0008381 mechanosensitive monoatomic ion channel activity 1/1486 19/18639 0.0526315789473684 0.660161507402423 0.79389586968065 0.953342884516617 GO:0031420 alkali metal ion binding 1/1486 19/18639 0.0526315789473684 0.660161507402423 0.79389586968065 0.953342884516617 GO:0034987 immunoglobulin receptor binding 1/1486 19/18639 0.0526315789473684 0.660161507402423 0.79389586968065 0.953342884516617 GO:0042834 peptidoglycan binding 1/1486 19/18639 0.0526315789473684 0.660161507402423 0.79389586968065 0.953342884516617 GO:0120227 acyl-CoA binding 1/1486 19/18639 0.0526315789473684 0.660161507402423 0.79389586968065 0.953342884516617 GO:0140223 general transcription initiation factor activity 4/1486 68/18639 0.0588235294117647 0.737827567096825 0.801445757871027 0.956755965687848 GO:0008146 sulfotransferase activity 3/1486 53/18639 0.0566037735849057 0.709985017395058 0.805447022766648 0.956755965687848 GO:0016251 RNA polymerase II general transcription initiation factor activity 3/1486 53/18639 0.0566037735849057 0.709985017395058 0.805447022766648 0.956755965687848 GO:0034212 protein N-acetyltransferase activity 3/1486 53/18639 0.0566037735849057 0.709985017395058 0.805447022766648 0.956755965687848 GO:0030280 structural constituent of skin epidermis 2/1486 37/18639 0.0540540540540541 0.678003710305191 0.805865763106511 0.956755965687848 GO:0070001 aspartic-type peptidase activity 2/1486 37/18639 0.0540540540540541 0.678003710305191 0.805865763106511 0.956755965687848 GO:0001972 retinoic acid binding 1/1486 20/18639 0.05 0.627153432032302 0.810344351831808 0.956755965687848 GO:0015464 acetylcholine receptor activity 1/1486 20/18639 0.05 0.627153432032302 0.810344351831808 0.956755965687848 GO:0052745 inositol phosphate phosphatase activity 1/1486 20/18639 0.05 0.627153432032302 0.810344351831808 0.956755965687848 GO:0140939 histone H4 methyltransferase activity 1/1486 20/18639 0.05 0.627153432032302 0.810344351831808 0.956755965687848 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 2/1486 38/18639 0.0526315789473684 0.660161507402423 0.817684205396497 0.956755965687848 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 15/1486 229/18639 0.0655021834061135 0.821598382575067 0.820758601139138 0.956755965687848 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 16/1486 243/18639 0.065843621399177 0.825881062758586 0.821082347320797 0.956755965687848 GO:0016798 hydrolase activity, acting on glycosyl bonds 8/1486 130/18639 0.0615384615384615 0.771881147116679 0.822902375430989 0.956755965687848 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 8/1486 130/18639 0.0615384615384615 0.771881147116679 0.822902375430989 0.956755965687848 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/1486 21/18639 0.0476190476190476 0.597288982887906 0.825480948489949 0.956755965687848 GO:0010314 phosphatidylinositol-5-phosphate binding 1/1486 21/18639 0.0476190476190476 0.597288982887906 0.825480948489949 0.956755965687848 GO:0036122 BMP binding 1/1486 21/18639 0.0476190476190476 0.597288982887906 0.825480948489949 0.956755965687848 GO:0061891 calcium ion sensor activity 1/1486 21/18639 0.0476190476190476 0.597288982887906 0.825480948489949 0.956755965687848 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 5/1486 86/18639 0.0581395348837209 0.729248176781746 0.825512165848663 0.956755965687848 GO:0004676 3-phosphoinositide-dependent protein kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:0004711 ribosomal protein S6 kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:0035175 histone H3S10 kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:0035979 histone H2AXS139 kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:0044022 histone H3S28 kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:0044023 histone H4S1 kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:0044024 histone H2AS1 kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:0044025 histone H2BS14 kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:0072354 histone H3T3 kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:0072371 histone H2AS121 kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:0072518 Rho-dependent protein serine/threonine kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:0140823 histone H2BS36 kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:0140855 histone H3S57 kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:0140995 histone H2A kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:0140997 histone H4 kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:0140998 histone H2B kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:1990244 histone H2AT120 kinase activity 16/1486 245/18639 0.0653061224489796 0.819139176531986 0.830458695126208 0.956755965687848 GO:0004677 DNA-dependent protein kinase activity 16/1486 246/18639 0.0650406504065041 0.815809342481043 0.835007937128872 0.956755965687848 GO:0140857 histone H3T45 kinase activity 16/1486 246/18639 0.0650406504065041 0.815809342481043 0.835007937128872 0.956755965687848 GO:0042379 chemokine receptor binding 4/1486 72/18639 0.0555555555555556 0.696837146702557 0.835977458698155 0.956755965687848 GO:0004532 RNA exonuclease activity 2/1486 40/18639 0.05 0.627153432032302 0.839402516965619 0.956755965687848 GO:0015144 carbohydrate transmembrane transporter activity 2/1486 40/18639 0.05 0.627153432032302 0.839402516965619 0.956755965687848 GO:0032451 demethylase activity 2/1486 40/18639 0.05 0.627153432032302 0.839402516965619 0.956755965687848 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/1486 40/18639 0.05 0.627153432032302 0.839402516965619 0.956755965687848 GO:0071855 neuropeptide receptor binding 2/1486 40/18639 0.05 0.627153432032302 0.839402516965619 0.956755965687848 GO:0008093 cytoskeletal anchor activity 1/1486 22/18639 0.0454545454545455 0.570139483665729 0.83941022717423 0.956755965687848 GO:0008649 rRNA methyltransferase activity 1/1486 22/18639 0.0454545454545455 0.570139483665729 0.83941022717423 0.956755965687848 GO:0008970 phospholipase A1 activity 1/1486 22/18639 0.0454545454545455 0.570139483665729 0.83941022717423 0.956755965687848 GO:0016881 acid-amino acid ligase activity 1/1486 22/18639 0.0454545454545455 0.570139483665729 0.83941022717423 0.956755965687848 GO:0050321 tau-protein kinase activity 1/1486 22/18639 0.0454545454545455 0.570139483665729 0.83941022717423 0.956755965687848 GO:0035403 histone H3T6 kinase activity 16/1486 247/18639 0.0647773279352227 0.812506470649136 0.839465391960791 0.956755965687848 GO:0004679 AMP-activated protein kinase activity 16/1486 248/18639 0.0645161290322581 0.809230234880389 0.843831743034167 0.960773529955154 GO:0008509 monoatomic anion transmembrane transporter activity 9/1486 149/18639 0.0604026845637584 0.757635018562512 0.848798635240088 0.96265565002761 GO:0003887 DNA-directed DNA polymerase activity 1/1486 23/18639 0.0434782608695652 0.545350810462871 0.852228425724968 0.96265565002761 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/1486 23/18639 0.0434782608695652 0.545350810462871 0.852228425724968 0.96265565002761 GO:0016493 C-C chemokine receptor activity 1/1486 23/18639 0.0434782608695652 0.545350810462871 0.852228425724968 0.96265565002761 GO:0042171 lysophosphatidic acid acyltransferase activity 1/1486 23/18639 0.0434782608695652 0.545350810462871 0.852228425724968 0.96265565002761 GO:0070577 lysine-acetylated histone binding 1/1486 23/18639 0.0434782608695652 0.545350810462871 0.852228425724968 0.96265565002761 GO:0071617 lysophospholipid acyltransferase activity 1/1486 23/18639 0.0434782608695652 0.545350810462871 0.852228425724968 0.96265565002761 GO:0140102 catalytic activity, acting on a rRNA 1/1486 23/18639 0.0434782608695652 0.545350810462871 0.852228425724968 0.96265565002761 GO:0008528 G protein-coupled peptide receptor activity 7/1486 122/18639 0.0573770491803279 0.719684266266576 0.863193836803687 0.970221769724928 GO:0004806 triacylglycerol lipase activity 1/1486 24/18639 0.0416666666666667 0.522627860026918 0.864024115420536 0.970221769724928 GO:0005315 phosphate transmembrane transporter activity 1/1486 24/18639 0.0416666666666667 0.522627860026918 0.864024115420536 0.970221769724928 GO:0019957 C-C chemokine binding 1/1486 24/18639 0.0416666666666667 0.522627860026918 0.864024115420536 0.970221769724928 GO:0030552 cAMP binding 1/1486 24/18639 0.0416666666666667 0.522627860026918 0.864024115420536 0.970221769724928 GO:0140033 acetylation-dependent protein binding 1/1486 24/18639 0.0416666666666667 0.522627860026918 0.864024115420536 0.970221769724928 GO:0031267 small GTPase binding 18/1486 283/18639 0.0636042402826855 0.797792351701868 0.870651983130215 0.97593568055676 GO:0140767 enzyme-substrate adaptor activity 8/1486 139/18639 0.0575539568345324 0.721903231116318 0.873405417567055 0.97593568055676 GO:0003707 nuclear steroid receptor activity 1/1486 25/18639 0.04 0.501722745625841 0.874878811337006 0.97593568055676 GO:0004709 MAP kinase kinase kinase activity 1/1486 25/18639 0.04 0.501722745625841 0.874878811337006 0.97593568055676 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/1486 25/18639 0.04 0.501722745625841 0.874878811337006 0.97593568055676 GO:0019707 protein-cysteine S-acyltransferase activity 1/1486 25/18639 0.04 0.501722745625841 0.874878811337006 0.97593568055676 GO:0005096 GTPase activator activity 17/1486 271/18639 0.0627306273062731 0.786834564173367 0.878280359599909 0.97593568055676 GO:0042605 peptide antigen binding 2/1486 45/18639 0.0444444444444444 0.557469717362046 0.883793359274085 0.97593568055676 GO:0140303 intramembrane lipid transporter activity 2/1486 45/18639 0.0444444444444444 0.557469717362046 0.883793359274085 0.97593568055676 GO:0001637 G protein-coupled chemoattractant receptor activity 1/1486 26/18639 0.0384615384615385 0.482425716947924 0.88486753414528 0.97593568055676 GO:0004435 phosphatidylinositol phospholipase C activity 1/1486 26/18639 0.0384615384615385 0.482425716947924 0.88486753414528 0.97593568055676 GO:0004950 chemokine receptor activity 1/1486 26/18639 0.0384615384615385 0.482425716947924 0.88486753414528 0.97593568055676 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/1486 26/18639 0.0384615384615385 0.482425716947924 0.88486753414528 0.97593568055676 GO:0008157 protein phosphatase 1 binding 1/1486 26/18639 0.0384615384615385 0.482425716947924 0.88486753414528 0.97593568055676 GO:0030247 polysaccharide binding 1/1486 26/18639 0.0384615384615385 0.482425716947924 0.88486753414528 0.97593568055676 GO:0043548 phosphatidylinositol 3-kinase binding 1/1486 26/18639 0.0384615384615385 0.482425716947924 0.88486753414528 0.97593568055676 GO:0051139 metal cation:proton antiporter activity 1/1486 26/18639 0.0384615384615385 0.482425716947924 0.88486753414528 0.97593568055676 GO:0097602 cullin family protein binding 1/1486 26/18639 0.0384615384615385 0.482425716947924 0.88486753414528 0.97593568055676 GO:0005085 guanyl-nucleotide exchange factor activity 14/1486 230/18639 0.0608695652173913 0.763491134648019 0.885349706704732 0.97593568055676 GO:0004180 carboxypeptidase activity 2/1486 46/18639 0.0434782608695652 0.545350810462871 0.891183372203846 0.97798443646603 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/1486 46/18639 0.0434782608695652 0.545350810462871 0.891183372203846 0.97798443646603 GO:0001653 peptide receptor activity 7/1486 128/18639 0.0546875 0.68594906628533 0.892993626879487 0.97798443646603 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/1486 27/18639 0.037037037037037 0.464558097801705 0.894059327207124 0.97798443646603 GO:0005044 scavenger receptor activity 1/1486 27/18639 0.037037037037037 0.464558097801705 0.894059327207124 0.97798443646603 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/1486 27/18639 0.037037037037037 0.464558097801705 0.894059327207124 0.97798443646603 GO:0035255 ionotropic glutamate receptor binding 1/1486 27/18639 0.037037037037037 0.464558097801705 0.894059327207124 0.97798443646603 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/1486 27/18639 0.037037037037037 0.464558097801705 0.894059327207124 0.97798443646603 GO:0008168 methyltransferase activity 12/1486 204/18639 0.0588235294117647 0.737827567096825 0.896622960452722 0.979850163480391 GO:0061733 protein-lysine-acetyltransferase activity 2/1486 47/18639 0.0425531914893617 0.533747601729618 0.898134666461425 0.980563851911039 GO:0005125 cytokine activity 14/1486 234/18639 0.0598290598290598 0.750440004141215 0.8989999265449 0.980571075562823 GO:0016298 lipase activity 7/1486 130/18639 0.0538461538461538 0.675396003727094 0.901625316423651 0.980661513361728 GO:0050698 proteoglycan sulfotransferase activity 1/1486 28/18639 0.0357142857142857 0.44796673716593 0.902517732524673 0.980661513361728 GO:0051959 dynein light intermediate chain binding 1/1486 28/18639 0.0357142857142857 0.44796673716593 0.902517732524673 0.980661513361728 GO:0141052 histone H3 demethylase activity 1/1486 28/18639 0.0357142857142857 0.44796673716593 0.902517732524673 0.980661513361728 GO:0008188 neuropeptide receptor activity 2/1486 48/18639 0.0416666666666667 0.522627860026918 0.904670166631504 0.981133267135022 GO:0032266 phosphatidylinositol-3-phosphate binding 2/1486 48/18639 0.0416666666666667 0.522627860026918 0.904670166631504 0.981133267135022 GO:0030165 PDZ domain binding 4/1486 83/18639 0.0481927710843374 0.604485235693785 0.905913989822616 0.981550072464352 GO:0004181 metallocarboxypeptidase activity 1/1486 29/18639 0.0344827586206897 0.432519608298139 0.910301228815487 0.984435609192506 GO:0099604 ligand-gated calcium channel activity 1/1486 29/18639 0.0344827586206897 0.432519608298139 0.910301228815487 0.984435609192506 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 16/1486 268/18639 0.0597014925373134 0.748839918844539 0.913395590613326 0.985647667785705 GO:0032813 tumor necrosis factor receptor superfamily binding 2/1486 50/18639 0.04 0.501722745625841 0.916581155100915 0.985647667785705 GO:0048020 CCR chemokine receptor binding 2/1486 50/18639 0.04 0.501722745625841 0.916581155100915 0.985647667785705 GO:0035091 phosphatidylinositol binding 17/1486 284/18639 0.0598591549295775 0.750817489052755 0.917200838554324 0.985647667785705 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/1486 30/18639 0.0333333333333333 0.418102288021534 0.917463634725223 0.985647667785705 GO:0032452 histone demethylase activity 1/1486 30/18639 0.0333333333333333 0.418102288021534 0.917463634725223 0.985647667785705 GO:0070566 adenylyltransferase activity 1/1486 30/18639 0.0333333333333333 0.418102288021534 0.917463634725223 0.985647667785705 GO:0005253 monoatomic anion channel activity 5/1486 103/18639 0.0485436893203883 0.608886827215827 0.921167499096312 0.988080726688708 GO:0005184 neuropeptide hormone activity 1/1486 31/18639 0.032258064516129 0.404615117440195 0.924054479950561 0.988080726688708 GO:0005452 solute:inorganic anion antiporter activity 1/1486 31/18639 0.032258064516129 0.404615117440195 0.924054479950561 0.988080726688708 GO:0016411 acylglycerol O-acyltransferase activity 1/1486 31/18639 0.032258064516129 0.404615117440195 0.924054479950561 0.988080726688708 GO:0140457 protein demethylase activity 1/1486 31/18639 0.032258064516129 0.404615117440195 0.924054479950561 0.988080726688708 GO:0016782 transferase activity, transferring sulphur-containing groups 3/1486 70/18639 0.0428571428571429 0.537560084599116 0.92531016735488 0.988497858858066 GO:0016651 oxidoreductase activity, acting on NAD(P)H 4/1486 88/18639 0.0454545454545455 0.570139483665729 0.927858572432333 0.990293915624041 GO:0160041 neuropeptide activity 1/1486 32/18639 0.03125 0.391970895020188 0.930119346824672 0.991779919770099 GO:0051018 protein kinase A binding 2/1486 53/18639 0.0377358490566038 0.473323344930039 0.931852369513947 0.992036657101464 GO:0000149 SNARE binding 5/1486 106/18639 0.0471698113207547 0.591654181162549 0.932097489553302 0.992036657101464 GO:0019239 deaminase activity 1/1486 33/18639 0.0303030303030303 0.380092989110486 0.935700184714635 0.993369688055659 GO:0030296 protein tyrosine kinase activator activity 1/1486 33/18639 0.0303030303030303 0.380092989110486 0.935700184714635 0.993369688055659 GO:0008234 cysteine-type peptidase activity 10/1486 187/18639 0.053475935828877 0.670752333724387 0.93605648796269 0.993369688055659 GO:0001217 DNA-binding transcription repressor activity 16/1486 278/18639 0.0575539568345324 0.721903231116318 0.937153185434142 0.993369688055659 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 4/1486 91/18639 0.043956043956044 0.551343676511914 0.938696869681951 0.993369688055659 GO:0008374 O-acyltransferase activity 2/1486 55/18639 0.0363636363636364 0.456111586932583 0.940519941652527 0.993369688055659 GO:0008175 tRNA methyltransferase activity 1/1486 34/18639 0.0294117647058824 0.368913783548413 0.940835599393451 0.993369688055659 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/1486 34/18639 0.0294117647058824 0.368913783548413 0.940835599393451 0.993369688055659 GO:0035064 methylated histone binding 3/1486 74/18639 0.0405405405405405 0.508502782728893 0.941178636143803 0.993369688055659 GO:0140034 methylation-dependent protein binding 3/1486 76/18639 0.0394736842105263 0.495121130551817 0.947884051210345 0.998891880010934 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/1486 36/18639 0.0277777777777778 0.348418573351279 0.949909441061186 0.998891880010934 GO:0016409 palmitoyltransferase activity 1/1486 36/18639 0.0277777777777778 0.348418573351279 0.949909441061186 0.998891880010934 GO:0045505 dynein intermediate chain binding 1/1486 36/18639 0.0277777777777778 0.348418573351279 0.949909441061186 0.998891880010934 GO:0001216 DNA-binding transcription activator activity 30/1486 491/18639 0.0610997963340122 0.766378939347008 0.952691419444443 0.999999985404532 GO:0004896 cytokine receptor activity 4/1486 96/18639 0.0416666666666667 0.522627860026918 0.953512821396678 0.999999985404532 GO:0031593 polyubiquitin modification-dependent protein binding 2/1486 59/18639 0.0338983050847458 0.425188767479526 0.954810902617975 0.999999985404532 GO:0001540 amyloid-beta binding 3/1486 83/18639 0.036144578313253 0.453363926770338 0.966143882852057 0.999999985404532 GO:0004812 aminoacyl-tRNA ligase activity 1/1486 41/18639 0.024390243902439 0.305928503430391 0.966966169939099 0.999999985404532 GO:0008227 G protein-coupled amine receptor activity 1/1486 41/18639 0.024390243902439 0.305928503430391 0.966966169939099 0.999999985404532 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/1486 41/18639 0.024390243902439 0.305928503430391 0.966966169939099 0.999999985404532 GO:0004402 histone acetyltransferase activity 1/1486 42/18639 0.0238095238095238 0.298644491443953 0.969605608129792 0.999999985404532 GO:0008173 RNA methyltransferase activity 2/1486 67/18639 0.0298507462686567 0.37441995942227 0.974164778886559 0.999999985404532 GO:0016790 thiolester hydrolase activity 1/1486 44/18639 0.0227272727272727 0.285069741832864 0.974269013868963 0.999999985404532 GO:0005126 cytokine receptor binding 14/1486 275/18639 0.0509090909090909 0.638556221705616 0.976578688520211 0.999999985404532 GO:0019783 ubiquitin-like protein peptidase activity 5/1486 127/18639 0.0393700787401575 0.493821600025434 0.977552196003779 0.999999985404532 GO:0030276 clathrin binding 1/1486 46/18639 0.0217391304347826 0.272675405231435 0.978217321113725 0.999999985404532 GO:0140098 catalytic activity, acting on RNA 21/1486 387/18639 0.0542635658914729 0.680631631662963 0.979892545901811 0.999999985404532 GO:0015085 calcium ion transmembrane transporter activity 6/1486 147/18639 0.0408163265306122 0.511961985332491 0.980054680506446 0.999999985404532 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 27/1486 484/18639 0.0557851239669422 0.699716639044303 0.983896768684786 0.999999985404532 GO:0101005 deubiquitinase activity 4/1486 115/18639 0.0347826086956522 0.436280648370297 0.98458341685585 0.999999985404532 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/1486 53/18639 0.0188679245283019 0.236661672465019 0.987842637322088 0.999999985404532 GO:0140101 catalytic activity, acting on a tRNA 5/1486 139/18639 0.0359712230215827 0.451189519447699 0.988559191420198 0.999999985404532 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/1486 56/18639 0.0178571428571429 0.223983368582965 0.990531878701363 0.999999985404532 GO:0015081 sodium ion transmembrane transporter activity 6/1486 164/18639 0.0365853658536585 0.458892755145586 0.992031560695004 0.999999985404532 GO:0015103 inorganic anion transmembrane transporter activity 6/1486 165/18639 0.0363636363636364 0.456111586932583 0.992461640030119 0.999999985404532 GO:0022824 transmitter-gated monoatomic ion channel activity 1/1486 63/18639 0.0158730158730159 0.199096327629302 0.994717375518306 0.999999985404532 GO:0022835 transmitter-gated channel activity 1/1486 63/18639 0.0158730158730159 0.199096327629302 0.994717375518306 0.999999985404532 GO:0140030 modification-dependent protein binding 6/1486 173/18639 0.0346820809248555 0.435019721640903 0.99519044949705 0.999999985404532 GO:0140375 immune receptor activity 5/1486 156/18639 0.032051282051282 0.402021430789937 0.995777118153714 0.999999985404532 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/1486 67/18639 0.0149253731343284 0.187209979711135 0.996215600449508 0.999999985404532 GO:0098960 postsynaptic neurotransmitter receptor activity 1/1486 69/18639 0.0144927536231884 0.181783603487624 0.996796989204686 0.999999985404532 GO:0015108 chloride transmembrane transporter activity 3/1486 121/18639 0.0247933884297521 0.310985172908579 0.99722093843189 0.999999985404532 GO:0030527 structural constituent of chromatin 2/1486 98/18639 0.0204081632653061 0.255980992666245 0.997285115329307 0.999999985404532 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/1486 73/18639 0.0136986301369863 0.171822858091042 0.997705664994114 0.999999985404532 GO:0004843 cysteine-type deubiquitinase activity 2/1486 108/18639 0.0185185185185185 0.232279048900852 0.99871460498722 0.999999985404532 GO:0005254 chloride channel activity 1/1486 83/18639 0.0120481927710843 0.151121308923446 0.999003997521089 0.999999985404532 GO:0030594 neurotransmitter receptor activity 1/1486 97/18639 0.0103092783505155 0.129309985986042 0.999690569499373 0.999999985404532 GO:0005249 voltage-gated potassium channel activity 1/1486 98/18639 0.0102040816326531 0.127990496333123 0.999715367995972 0.999999985404532 GO:0019787 ubiquitin-like protein transferase activity 20/1486 479/18639 0.0417536534446764 0.523718941154323 0.999737755058852 0.999999985404532 GO:0005262 calcium channel activity 2/1486 131/18639 0.0152671755725191 0.191497231154901 0.999775828795708 0.999999985404532 GO:0004842 ubiquitin-protein transferase activity 18/1486 449/18639 0.0400890868596882 0.50284016822189 0.999785665966527 0.999999985404532 GO:0099094 ligand-gated monoatomic cation channel activity 2/1486 136/18639 0.0147058823529412 0.184456891774206 0.99984727355988 0.999999985404532 GO:0016755 aminoacyltransferase activity 20/1486 496/18639 0.0403225806451613 0.505768896800243 0.999880370618616 0.999999985404532 GO:0046873 metal ion transmembrane transporter activity 17/1486 450/18639 0.0377777777777778 0.473849259757739 0.999912810173427 0.999999985404532 GO:0005244 voltage-gated monoatomic ion channel activity 3/1486 173/18639 0.0173410404624277 0.217509860820451 0.999930592187165 0.999999985404532 GO:0003823 antigen binding 3/1486 174/18639 0.0172413793103448 0.216259804149069 0.999935477539862 0.999999985404532 GO:0022832 voltage-gated channel activity 3/1486 175/18639 0.0171428571428571 0.215024033839646 0.999940022773887 0.999999985404532 GO:0061630 ubiquitin protein ligase activity 11/1486 353/18639 0.0311614730878187 0.390860495884154 0.999958755292771 0.999999985404532 GO:0005267 potassium channel activity 1/1486 124/18639 0.00806451612903226 0.101153779360049 0.999967618077889 0.999999985404532 GO:0061659 ubiquitin-like protein ligase activity 11/1486 372/18639 0.0295698924731183 0.370897190986845 0.999986160930074 0.999999985404532 GO:0045182 translation regulator activity 10/1486 356/18639 0.0280898876404494 0.352333388782192 0.999989100606969 0.999999985404532 GO:0022843 voltage-gated monoatomic cation channel activity 1/1486 143/18639 0.00699300699300699 0.0877137667178044 0.999993399216046 0.999999985404532 GO:0015276 ligand-gated monoatomic ion channel activity 2/1486 186/18639 0.010752688172043 0.134871705813398 0.999996899328259 0.999999985404532 GO:0022834 ligand-gated channel activity 2/1486 188/18639 0.0106382978723404 0.133436900432405 0.99999735176974 0.999999985404532 GO:0015079 potassium ion transmembrane transporter activity 1/1486 160/18639 0.00625 0.0783941790040377 0.99999841157461 0.999999985404532 GO:0022836 gated channel activity 6/1486 318/18639 0.0188679245283019 0.236661672465019 0.999999552754181 0.999999985404532 GO:0030371 translation repressor activity 5/1486 329/18639 0.0151975683890578 0.190624143474864 0.999999965002227 0.999999985404532 GO:0005216 monoatomic ion channel activity 10/1486 448/18639 0.0223214285714286 0.279979210728706 0.999999965558539 0.999999985404532 GO:0005261 monoatomic cation channel activity 5/1486 341/18639 0.0146627565982405 0.183915962472816 0.999999985404532 0.999999985404532