category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Genetic Information Processing	Translation	hsa03010	Ribosome	57/379	222/9376	6.35185053127006	RPL29/RPS18/RPS4Y1/RPS2/RPLP0/RPL8/RPL7A/RPL27A/RPL3/RPS19/RPS11/RPS23/RPS7/RPL10A/RPS5/RPS6/RPS16/RPS13/RPL15/RPL9/RPL11/RPL18/RPS3A/RPL18A/RPL13/RPLP1/RPL22/RPL37A/RPL6/RPSA/RPS9/RPL36/RPL7/RPL26/RPL14/RPL23/RPL35/RPS12/RPL13A/RPL24/RPS15/UBA52/RPL5/RPL32/RPL39/RPS4X/RPS20/MRPS15/RPS14/RPL12/RPS24/RPS27A/MRPL51/RPL35A/RPL31/MRPL15/RPS27L	16.5627097758367
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	57/379	238/9376	5.924835369504	RPL29/RPS18/RPS4Y1/RPS2/RPLP0/RPL8/RPL7A/RPL27A/RPL3/RPS19/RPS11/RPS23/RPS7/RPL10A/RPS5/RPS6/RPS16/RPS13/RPL15/RPL9/RPL11/RPL18/RPS3A/RPL18A/RPL13/RPLP1/RPL22/RPL37A/RPL6/RPSA/RPS9/RPL36/RPL7/RPL26/RPL14/RPL23/RPL35/RPS12/RPL13A/RPL24/CFD/C1R/RPS15/UBA52/RPL5/RPL32/RPL39/RPS4X/RPS20/RPS14/RPL12/RPS24/RPS27A/C1S/RPL35A/RPL31/RPS27L	15.7946861931986
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	33/379	268/9376	3.04619383294609	TUBA1B/TUBA1C/UQCRH/NDUFA4/TUBB/TXN/TUBB6/UQCR10/COX6A2/UBA52/SLC25A5/PSMB1/MT-CO3/COX5A/GNAI1/SNCA/MAOA/RPS27A/COX6C/SLC18A2/PSMB7/PSMB5/COX5B/NDUFB2/PSMC1/GNAS/COX7A2L/COX7B/PSMB6/NDUFA6/NDUFA11/NDUFAB1/SLC39A1	6.97523815679574
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	12/379	59/9376	5.03161754841018	GPX3/GSTP1/MGST3/GSTA4/IDH1/PRDX6/GSTO2/GGCT/RRM2/MGST1/IDH2/GSTA3	6.37563825640557
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	30/379	308/9376	2.4096220402289	GPX3/TUBA1B/TUBA1C/UQCRH/TGM2/NDUFA4/TUBB/TUBB6/UQCR10/PPARG/COX6A2/CLTA/SLC25A5/PSMB1/MT-CO3/COX5A/SLC1A2/COX6C/PSMB7/PSMB5/COX5B/NDUFB2/PSMC1/COX7A2L/COX7B/POLR2L/PSMB6/NDUFA6/NDUFA11/NDUFAB1	5.16272113277842
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	14/379	87/9376	3.98095411397204	MYL4/UQCRH/TPM2/FXYD2/TPM1/UQCR10/COX6A2/MT-CO3/COX5A/COX6C/COX5B/COX7A2L/COX7B/TPM4	5.73306438026672
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	17/379	138/9376	3.0475316431494	UQCRH/NDUFA4/UQCR10/COX6A2/PPA1/ATP6V1C2/MT-CO3/COX5A/COX6C/COX5B/NDUFB2/COX7A2L/COX7B/NDUFA6/NDUFA11/NDUFAB1/ATP6V1B1	4.97321883052995
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	25/379	275/9376	2.24898057088031	TUBA1B/TUBA1C/UQCRH/NDUFA4/CAV1/TUBB/TUBB6/UQCR10/COX6A2/SLC25A5/PSMB1/MT-CO3/COX5A/COX6C/PSMB7/PSMB5/COX5B/NDUFB2/PSMC1/COX7A2L/COX7B/PSMB6/NDUFA6/NDUFA11/NDUFAB1	4.31453359762746
NA	NA	hsa04382	Cornified envelope formation	21/379	217/9376	2.39407609158226	KRT18/S100A11/KRT19/KRT7/KRT23/S100A13/KRT8/DSP/CLDN7/CLDN4/S100A1/CLDN10/CLDN3/CLDN6/KAZN/DSG2/PKP3/JUP/COL4A2/PADI1/PKP2	4.2643093191008
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	8/379	41/9376	4.82708024969432	ALAS2/GCSH/ALDH7A1/PHGDH/MAOA/GLDC/CBS/GCAT	5.04032707185898
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	20/379	205/9376	2.41354012484716	GAPDH/UQCRH/NDUFA4/SLC2A1/MMP2/UQCR10/COX6A2/SLC25A5/MT-CO3/COX5A/COX6C/COX5B/NDUFB2/PRKCZ/COX7A2L/COX7B/COL1A1/NDUFA6/NDUFA11/NDUFAB1	4.1998435019929
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	17/379	170/9376	2.47387862796834	TUBA1B/TUBA1C/CLDN7/CLDN4/CLDN10/CLDN3/MYL6/ARPC1A/CLDN6/RAB13/CTTN/ACTG1/PARD3/JAM3/PRKCZ/YBX3/MPDZ	3.98022001937004
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	16/379	157/9376	2.52115019410786	LEP/UQCRH/NDUFA4/UQCR10/PPARG/COX6A2/MT-CO3/COX5A/COX6C/COX5B/NDUFB2/COX7A2L/COX7B/NDUFA6/NDUFA11/NDUFAB1	3.94490363500091
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	15/379	142/9376	2.61325207179754	GSTP1/MGST3/CAV1/TXN/GSTA4/MMP2/RAC3/GSTO2/ACTG1/BMP4/MGST1/PRKCZ/ASS1/GSTA3/CDH5	3.97564732375182
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	10/379	75/9376	3.29850483729112	GAPDH/ARG2/ALDOA/PHGDH/IDH1/ENO1/IDH2/TALDO1/ASS1/CBS	4.10173515083271
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	20/379	227/9376	2.17962874710867	MGST3/UQCRH/NDUFA4/GSTA4/UQCR10/COX6A2/SLC25A5/MT-CO3/COX5A/GSTO2/COX6C/MGST1/COX5B/NDUFB2/COX7A2L/COX7B/NDUFA6/NDUFA11/GSTA3/NDUFAB1	3.69256241895049
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	10/379	82/9376	3.01692515605895	GSTP1/MGST3/GSTA4/IMPDH2/GSTO2/RRM2/MGST1/NME1/TK1/GSTA3	3.76488537078041
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	27/379	368/9376	1.81507399334634	GPX3/TUBA1B/TUBA1C/UQCRH/NDUFA4/TUBB/TUBB6/UQCR10/COX6A2/PSMB1/MT-CO3/COX5A/SLC1A2/ACTG1/COX6C/SRSF3/PSMB7/PSMB5/COX5B/NDUFB2/PSMC1/COX7A2L/COX7B/PSMB6/NDUFA6/NDUFA11/NDUFAB1	3.27388288691533
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	28/379	388/9376	1.78527323667818	GAPDH/TUBA1B/TUBA1C/UQCRH/NDUFA4/TUBB/TUBB6/UQCR10/COX6A2/SLC25A5/PSMB1/MT-CO3/COX5A/SNCA/COX6C/PSMB7/PSMB5/COX5B/NDUFB2/PSMC1/MME/COX7A2L/COX7B/PSMB6/NDUFA6/NDUFA11/NDUFAB1/SLC39A1	3.24236206906294
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	12/379	116/9376	2.55918478755345	GAPDH/GCSH/PCCA/ALDOA/PHGDH/IDH1/ENO1/GLDC/IDH2/TALDO1/ECHS1/ADH5	3.46798709788031
NA	NA	hsa03272	Virion - Hepatitis viruses	7/379	48/9376	3.60773966578716	CLDN7/CLDN4/CLDN10/CD63/CLDN3/EPCAM/CLDN6	3.71746566436159
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	19/379	235/9376	2.00015718857015	RPS6/UQCRH/NDUFA4/UQCR10/PPARG/COX6A2/MT-CO3/COX5A/ACTG1/COX6C/COX5B/NDUFB2/GNAS/COX7A2L/COX7B/COA4/NDUFA6/NDUFA11/NDUFAB1	3.18685071893228
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	6/379	39/9376	3.80596711995129	GCSH/ALDH7A1/GLDC/CBS/AHCY/TYMS	3.6038572886614
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	18/379	233/9376	1.91115087139185	MYL4/TPM2/DSP/CSRP2/DSC2/TPM1/FBLN1/ENO1/PDLIM1/DSG2/ACTG1/TNNI2/JUP/COL4A2/COL1A1/FHL2/PKP2/TPM4	2.89054861782843
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	5/379	30/9376	4.1231310466139	ABCG2/GGH/FOLR1/SLC19A1/TYMS	3.51636808406952
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	11/379	116/9376	2.34591938859066	CLDN7/CLDN4/MMP2/CLDN10/CLDN3/CLDN6/CTNND1/GNAI1/ACTG1/JAM3/CDH5	2.99363559193228
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	8/379	73/9376	2.71109986626667	GSTP1/MGST3/GSTA4/GSTO2/MAOA/MGST1/ADH5/GSTA3	3.01218512743688
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	6/379	46/9376	3.22679821039348	PSMB1/POMP/PSMB7/PSMB5/PSMC1/PSMB6	3.10724387434804
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	8/379	75/9376	2.63880386983289	GSTP1/MGST3/GSTA4/GSTO2/MGST1/TOP2A/BIRC5/GSTA3	2.92448348559333
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	13/379	157/9376	2.04843453271264	YAP1/TEAD4/ID1/TEAD3/ACTG1/BMP7/CDH1/PARD3/BMP4/PRKCZ/BIRC5/YWHAE/FRMD6	2.71897753106771
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	13/379	158/9376	2.03546975718914	CDKN1C/CCNE1/CCNB1/SKP2/ANAPC11/CDK7/SFN/RBX1/CDC20/CCNB2/YWHAE/PTTG1/MAD2L1	2.69403971407182
NA	NA	hsa04519	Cadherin signaling	26/379	404/9376	1.59210010710834	KRT18/KRT19/KRT7/KRT23/KRT8/DSP/DSC2/ARPC1A/CTNND1/YAP1/TEAD4/RAC3/ENAH/DSG2/TEAD3/ACTG1/PKP3/JUP/CDH1/MYO1B/FLT4/YWHAE/DSC3/PKP2/CDH5/MPDZ	2.49687943667927
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	15/379	200/9376	1.85540897097625	GAPDH/TUBA1B/TUBA1C/CLDN7/CLDN4/TUBB/TUBB6/CLDN10/CLDN3/MYO10/ARPC1A/CLDN6/CTTN/ACTG1/MYO1B	2.50968074628914
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	5/379	37/9376	3.34307922698424	MIF/COMT/MAOA/GSTZ1/ADH5	2.93085296297522
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	6/379	52/9376	2.85447533996347	CGA/CYP11A1/CYP19A1/CYP2J2/GNAS/HSD3B1	2.75218729056367
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	7/379	67/9376	2.58464931280274	GAPDH/ALDH7A1/ALDOA/ENO1/GAPDHS/ADH5/LDHB	2.67162461254005
NA	NA	hsa04518	Integrin signaling	12/379	154/9376	1.92769763218312	PGF/LAMA4/RAC3/FERMT2/ACTG1/CDH1/LAMB1/FERMT1/FLT4/COL4A2/COL1A1/PARVA	2.38237779482456
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	15/379	212/9376	1.75038582167571	PGF/CTNND1/GNAI1/RAC3/ENAH/ID1/FGF7/ACTG1/CDH1/PARD3/KIT/FLT4/PRKCZ/GNAS/EFNA1	2.26812190399347
Cellular Processes	Cell motility	hsa04814	Motor proteins	14/379	194/9376	1.78527323667818	MYL4/TUBA1B/TUBA1C/TPM2/TUBB/TUBB6/DYNLL1/TPM1/MYO10/MYL6/ACTG1/TNNI2/MYO1B/TPM4	2.26834652232914
Environmental Information Processing	Signal transduction	hsa04392	Hippo signaling pathway - multiple species	4/379	29/9376	3.4122463834046	YAP1/TEAD4/TEAD3/FRMD6	2.67018237229234
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	7/379	75/9376	2.30895338610378	CCNE1/CCNB1/PERP/RRM2/SFN/SIVA1/CCNB2	2.33585765297364
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	28/379	480/9376	1.44309586631486	GPX3/TUBA1B/TUBA1C/UQCRH/NDUFA4/TUBB/TUBB6/UQCR10/COX6A2/UBA52/SLC25A5/PSMB1/MT-CO3/COX5A/SNCA/RPS27A/COX6C/PSMB7/PSMB5/COX5B/NDUFB2/PSMC1/COX7A2L/COX7B/PSMB6/NDUFA6/NDUFA11/NDUFAB1	2.04539557935528
NA	NA	hsa04981	Folate transport and metabolism	4/379	31/9376	3.19210145544302	ABCG2/FOLR1/SLC19A1/TYMS	2.50904371116896
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	5/379	46/9376	2.68899850866124	BLVRB/ALAS2/CP/HMBS/UROD	2.35680550007863
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	7/379	79/9376	2.192044353896	GSTP1/MGST3/GSTA4/GSTO2/MGST1/ADH5/GSTA3	2.18368971270644
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	8/379	99/9376	1.9990938407825	KRT18/KRT19/KRT23/CFD/DEFB1/C1R/C1S/HLA-DRB5	2.05105111437584
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	5/379	50/9376	2.47387862796834	ALDH7A1/ARG2/CKB/MAOA/CKMT1A	2.14464493392971
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	7/379	85/9376	2.03731181126804	PNP/IMPDH2/RRM2/NME1/TK1/NT5C3B/TYMS	1.97171408454802
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	8/379	103/9376	1.9214591285191	ARG2/LAMA4/PRDX1/SERPINB6/LAMB1/GNAS/COL4A2/COL1A1	1.92992726736401
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	11/379	160/9376	1.70079155672823	CLDN7/CLDN4/HLA-G/CLDN10/CLDN3/CNTNAP2/CLDN6/CDH1/JAM3/HLA-DRB5/CDH5	1.83499126801612
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	6/379	70/9376	2.12046739540143	GSTP1/MGST3/GSTA4/GSTO2/MGST1/GSTA3	1.93118154417035
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	5/379	54/9376	2.29062835922994	ADI1/PHGDH/CBS/AHCY/LDHB	1.95209036218964
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	8/379	110/9376	1.79918445670425	GAPDH/RPS6/ALDOA/SLC2A1/EGLN3/ENO1/RBX1/LDHB	1.73042828897998
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	7/379	93/9376	1.86205918234176	CTNND1/RAC3/ACTG1/CDH1/PARD3/ARHGAP29/CDH5	1.71471032982927
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	5/379	59/9376	2.09650731183757	RRM2/NME1/TK1/NT5C3B/TYMS	1.73402707023559
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	4/379	43/9376	2.30128244462171	ALDH7A1/ECHS1/ECI1/ADH5	1.75530079146281
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	6/379	78/9376	1.90298355997564	CAV1/CLTA/ARPC1A/CTTN/ACTG1/CDH1	1.64357208649576
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	10/379	155/9376	1.59605072772151	TUBA1B/TUBA1C/TUBB/TUBB6/HLA-G/C1R/ATP6V1C2/ACTG1/HLA-DRB5/ATP6V1B1	1.5357355708796
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	3/379	28/9376	2.65058424425179	AKR1B1/GGH/PCBD1	1.79520373011999
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	9/379	138/9376	1.61339910519674	CCNE1/CCNB1/ANAPC11/RBX1/CDC20/CCNB2/YWHAE/PTTG1/MAD2L1	1.48987586629061
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	6/379	83/9376	1.78834599612169	PRDX5/IDH1/PRDX1/ECH1/IDH2/PXMP2	1.48058834657663
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	13/379	224/9376	1.43573313230305	CCNE1/RAN/SLC2A1/HLA-G/MSX2/SLC25A5/RANBP1/ANAPC11/HLA-DRB5/CDC20/CCNB2/PTTG1/MAD2L1	1.35469949992575
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	4/379	48/9376	2.06156552330695	ALDH7A1/PCCA/ECHS1/HIBADH	1.51331570215327
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	3/379	31/9376	2.39407609158226	GCSH/PCCA/GLDC	1.5956368450878
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	6/379	86/9376	1.72596183346628	DSP/DSC2/DSG2/ACTG1/JUP/PKP2	1.38807055087351
Metabolism	Amino acid metabolism	hsa00360	Phenylalanine metabolism	2/379	16/9376	3.09234828496042	MIF/MAOA	1.71914467848217
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	4/379	49/9376	2.01949275752517	GNAI1/MAOA/SLC18A2/GNAS	1.46847845630351
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	3/379	32/9376	2.31926121372032	PCCA/ECHS1/LDHB	1.5342486562592
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	4/379	50/9376	1.97910290237467	HBA2/HBA1/GYPB/GYPA	1.42469538503873
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	6/379	88/9376	1.68673542816023	TFPI/CFD/C1R/SERPINB2/C1S/PROCR	1.32839144048093
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	4/379	51/9376	1.94029696311242	ATP6V1C2/ACTG1/GNAS/ATP6V1B1	1.38191739702242
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	6/379	89/9376	1.66778334469776	TUBA1B/TUBA1C/TUBB/TUBB6/GNAI1/GNAS	1.29911993337762
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	5/379	70/9376	1.76705616283453	CAV1/HLA-G/RAC3/ACTG1/HLA-DRB5	1.32205962537397
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	5/379	71/9376	1.74216804786503	SLC2A1/IDH1/KIT/IDH2/LDHB	1.2883374212321
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	4/379	53/9376	1.86707820978742	FXYD2/CLTA/GNAS/RAB11A	1.29919621875099
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	6/379	93/9376	1.59605072772151	CCNE1/LAMA4/CKS1B/SKP2/LAMB1/COL4A2	1.1855964890368
Metabolism	Metabolism of cofactors and vitamins	hsa00785	Lipoic acid metabolism	2/379	19/9376	2.60408276628246	GCSH/GLDC	1.43645373079263
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	3/379	37/9376	2.00584753619054	HBA2/HBA1/LAMA4	1.25816967595233
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	5/379	79/9376	1.56574596706857	CLTA/ATP6V1C2/SLC1A2/SLC18A2/ATP6V1B1	1.03638228246713
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	8/379	142/9376	1.39373443829202	UBA52/UBE2C/SKP2/ANAPC11/RHOBTB1/RPS27A/RBX1/CDC20	0.97030668252633
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	2/379	22/9376	2.24898057088031	ALDH7A1/MAOA	1.20371791199184
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	8/379	144/9376	1.37437701553797	DUSP9/ID4/DLX5/TBX3/ID1/ID3/BMP4/LIFR	0.929177979490027
NA	NA	hsa04517	IgSF CAM signaling	15/379	299/9376	1.24107623476672	TUBA1B/TUBA1C/TUBB/TUBB6/DYNLL1/CNTNAP2/MYL6/ARPC1A/ACTG1/CDH1/PARD3/JAM3/EPB41L3/CLMP/MPDZ	0.869511257656673
Metabolism	Amino acid metabolism	hsa00220	Arginine biosynthesis	2/379	23/9376	2.15119880692899	ARG2/ASS1	1.13447561302783
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	3/379	42/9376	1.76705616283453	ALDH7A1/MAOA/ECHS1	1.02252584395572
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	4/379	63/9376	1.57071658918625	PTGDS/PLA2G2A/PTGR1/CYP2J2	0.932829673631607
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	4/379	63/9376	1.57071658918625	CDK7/RBX1/POLR2L/GTF2H5	0.932829673631607
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	6/379	106/9376	1.40030865734057	GSTP1/CCNE1/SPINT1/ETV5/FOLR1/SLC19A1	0.850676491180946
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	3/379	44/9376	1.68673542816023	DYNLL1/GNAS/RAB11A	0.937097564208607
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	4/379	65/9376	1.52238684798052	CYP11A1/PBX1/GNAS/HSD3B1	0.867375462773777
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	7/379	130/9376	1.33208849198295	MMP2/GNAI1/GNG12/PRKCZ/GNAS/COL4A2/COL1A1	0.782537107271706
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	4/379	66/9376	1.49932038058687	CYP11A1/CYP19A1/COMT/HSD3B1	0.835473738213996
Organismal Systems	Digestive system	hsa04977	Vitamin digestion and absorption	2/379	26/9376	1.90298355997564	SLC19A1/SLC5A6	0.946274408468197
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	6/379	110/9376	1.34938834252818	ID4/ID1/BMP7/ID3/BMP4/RBX1	0.756510548570813
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	3/379	47/9376	1.57907146466064	ALDH7A1/ADH5/LDHB	0.816807900512568
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	7/379	134/9376	1.29232465640137	PLA2G2A/PPP1R14A/MYL6/CALD1/GNAS/RAMP2/RAMP1	0.699505684183224
Metabolism	Carbohydrate metabolism	hsa00650	Butanoate metabolism	2/379	27/9376	1.83250268738395	ECHS1/ACSM3	0.889080999886712
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	10/379	203/9376	1.2186594226445	PGF/LAMA4/CAV1/RAC3/ACTG1/LAMB1/FLT4/COL4A2/COL1A1/PARVA	0.646423151481535
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	2/379	28/9376	1.76705616283453	ATP6V1C2/ATP6V1B1	0.834263437039092
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	6/379	115/9376	1.29071928415739	GNAI1/MAOA/CYP2J2/GNG12/SLC18A2/GNAS	0.643798857461458
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	9/379	184/9376	1.21004932889756	GNAI1/RAC3/ENAH/SEMA6A/BMP7/PARD3/EPHB4/PRKCZ/EFNA1	0.590583874848283
Metabolism	Energy metabolism	hsa00920	Sulfur metabolism	1/379	10/9376	2.47387862796834	SELENBP1	0.957064103763033
Metabolism	Carbohydrate metabolism	hsa00020	Citrate cycle (TCA cycle)	2/379	30/9376	1.64925241864556	IDH1/IDH2	0.731000540597048
Metabolism	Lipid metabolism	hsa00591	Linoleic acid metabolism	2/379	30/9376	1.64925241864556	PLA2G2A/CYP2J2	0.731000540597048
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	2/379	31/9376	1.59605072772151	ALDOA/TALDO1	0.682229979006648
Metabolism	Metabolism of other amino acids	hsa00410	beta-Alanine metabolism	2/379	31/9376	1.59605072772151	ALDH7A1/ECHS1	0.682229979006648
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	4/379	75/9376	1.31940193491645	CGA/GPX3/FXYD2/GNAS	0.569980155114566
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	4/379	76/9376	1.30204138314123	GAST/GNAI1/ACTG1/GNAS	0.542610452126158
Human Diseases	Immune disease	hsa05310	Asthma	2/379	32/9376	1.54617414248021	FCER1G/HLA-DRB5	0.635178943691309
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	3/379	54/9376	1.37437701553797	CGA/HLA-G/HLA-DRB5	0.566249578068336
Metabolism	Global and overview maps	hsa01210	2-Oxocarboxylic acid metabolism	2/379	33/9376	1.49932038058687	IDH1/IDH2	0.589724908024102
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	4/379	78/9376	1.26865570665043	LSM4/ENO1/LSM3/LSM7	0.488995636133562
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	7/379	149/9376	1.16222485877707	NDUFA4/GNAI1/GNG12/NDUFB2/NDUFA6/NDUFA11/NDUFAB1	0.409672358003212
Organismal Systems	Immune system	hsa04611	Platelet activation	6/379	126/9376	1.17803744188968	FCER1G/GNAI1/ACTG1/PRKCZ/GNAS/COL1A1	0.412935418202036
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	2/379	35/9376	1.41364493026762	AKR1B1/ALDOA	0.503177745537826
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	5/379	105/9376	1.17803744188968	TPM2/TPM1/ACTG1/GNAS/TPM4	0.376529569270159
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	9/379	201/9376	1.10770684834403	NUPR1/LMO2/PPARG/SPINT1/PBX1/ETV5/JUP/HOXA10/MYCN	0.316806944726429
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	3/379	59/9376	1.25790438710254	CGA/GNAI1/GNAS	0.407852445615589
Metabolism	Carbohydrate metabolism	hsa00040	Pentose and glucuronate interconversions	2/379	36/9376	1.37437701553797	AKR1B1/DCXR	0.46189511914144
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	11/379	250/9376	1.08850659630607	CAV1/HLA-G/CLTA/ARPC1A/PARD3/FOLR1/SNX3/PRKCZ/DAB2/EPN3/RAB11A	0.291113130494369
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	7/379	154/9376	1.12449028544015	MYL4/TPM2/FXYD2/TPM1/GNAI1/GNAS/TPM4	0.319697799600991
Metabolism	Amino acid metabolism	hsa00250	Alanine, aspartate and glutamate metabolism	2/379	37/9376	1.3372316907937	RIMKLB/ASS1	0.421828032440875
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	2/379	37/9376	1.3372316907937	PPARG/CDH1	0.421828032440875
Organismal Systems	Digestive system	hsa04978	Mineral absorption	3/379	61/9376	1.2166616203123	MT1G/FXYD2/MT1H	0.348427044877209
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	6/379	133/9376	1.11603547126391	COMT/GNAI1/MAOA/GNG12/SLC18A2/GNAS	0.276609121483703
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	2/379	38/9376	1.30204138314123	PNP/QPRT	0.382902054693825
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	2/379	38/9376	1.30204138314123	FXYD2/SFN	0.382902054693825
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	5/379	110/9376	1.12449028544015	CCNB1/GNAI1/ANAPC11/CCNB2/MAD2L1	0.269551678366231
Metabolism	Glycan biosynthesis and metabolism	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/379	15/9376	1.64925241864556	B4GALNT1	0.516481138479752
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	3/379	63/9376	1.17803744188968	ALDH7A1/ECHS1/SMYD2	0.291000142555805
Human Diseases	Immune disease	hsa05330	Allograft rejection	2/379	39/9376	1.26865570665043	HLA-G/HLA-DRB5	0.345049241549715
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	6/379	137/9376	1.08345049400073	TUBA1B/TUBA1C/ACTG1/CTSV/BIRC5/CTSW	0.201944995363916
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	4/379	89/9376	1.11185556313184	LAMA4/LAMB1/COL4A2/COL1A1	0.217606193502054
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	6/379	139/9376	1.06786127825971	KRT18/KRT19/KRT23/MMP2/GNAI1/GNAS	0.1654323150104
Organismal Systems	Digestive system	hsa04976	Bile secretion	4/379	90/9376	1.09950161243037	FXYD2/SLC2A1/ABCG2/GNAS	0.194667484332752
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	2/379	41/9376	1.20677006242358	MMP2/CDH1	0.272319542650505
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	9/379	214/9376	1.04041624540724	CCNB1/HLA-G/AP1M2/GNAI1/RAC3/GNG12/RBX1/CCNB2/AP1S1	0.122750732334398
Metabolism	Energy metabolism	hsa00910	Nitrogen metabolism	1/379	17/9376	1.45522272233432	CA12	0.385558295484115
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	9/379	217/9376	1.02603261067811	MGST3/GSTA4/GNAI1/GSTO2/FGF7/MGST1/BIRC5/GNAS/GSTA3	0.0796305918920118
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	3/379	68/9376	1.09141704175074	CYP26A1/ALDH1A3/ADH5	0.155277959519804
Organismal Systems	Digestive system	hsa04980	Cobalamin transport and metabolism	1/379	18/9376	1.37437701553797	PRDX1	0.32629490534941
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	6/379	144/9376	1.03078276165347	SLC25A5/PSMB1/PSMB7/PSMB5/PSMC1/PSMB6	0.0764006952595559
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	3/379	69/9376	1.07559940346449	MAOA/SLC18A2/GNAS	0.129358341830417
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	7/379	170/9376	1.01865590563402	GSTP1/MGST3/GSTA4/GSTO2/ACTG1/MGST1/GSTA3	0.0503804096721088
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	2/379	44/9376	1.12449028544015	TUSC3/OSTC	0.169875527706695
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	2/379	44/9376	1.12449028544015	CDK7/GTF2H5	0.169875527706695
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	2/379	44/9376	1.12449028544015	HLA-G/HLA-DRB5	0.169875527706695
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	4/379	95/9376	1.04163310651298	ATP6V1C2/HLA-DRB5/CCL3L1/ATP6V1B1	0.0837065835703226
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	3/379	70/9376	1.06023369770072	SLC2A1/EGLN3/RBX1	0.103815787781209
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	2/379	45/9376	1.09950161243037	DEFB1/ABCG2	0.137318377614188
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	2/379	45/9376	1.09950161243037	HLA-G/HLA-DRB5	0.137318377614188
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	10/379	248/9376	0.997531704825943	GAPDH/TUBA1B/TUBA1C/TUBB/TXN/TUBB6/DYNLL1/ANXA2/ARPC1A/ACTG1	-0.00808521367268159
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	5/379	122/9376	1.01388468359358	FXYD2/SLC2A1/ACTG1/BMP4/DIO3	0.0316816314921641
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	3/379	71/9376	1.04530082871902	ATP6V1C2/JAM3/ATP6V1B1	0.0786381912013383
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	4/379	99/9376	0.999546920391248	TPM2/TPM1/ACTG1/TPM4	-0.00093013228437545
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	5/379	125/9376	0.989551451187335	FCER1G/GNAI1/RAC3/SPTSSA/PRKCZ	-0.0241364294756245
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	4/379	100/9376	0.989551451187335	GYPA/KIT/HLA-DRB5/MME	-0.0215591676099873
Metabolism	Glycan biosynthesis and metabolism	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/379	21/9376	1.17803744188968	DSEL	0.167631441621409
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	4/379	101/9376	0.979753912066668	MMP2/PRKCZ/COL4A2/COL1A1	-0.0419856836771743
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	13/379	333/9376	0.965778443351003	CCNE1/LAMA4/HLA-G/ATP6V1C2/PARD3/LAMB1/PSMC1/PRKCZ/GNAS/HEY1/COL4A2/COL1A1/ATP6V1B1	-0.130503450594704
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	5/379	128/9376	0.966358839050132	PNP/IMPDH2/RRM2/NME1/PAICS	-0.0786517575919619
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	6/379	154/9376	0.96384881609156	ALAS2/GGH/HMBS/QPRT/NME1/UROD	-0.0928381994437232
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	4/379	102/9376	0.970148481556211	PLA2G2A/FXYD2/GNAS/RAB11A	-0.0622141755244615
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	3/379	76/9376	0.976531037355923	PPARG/DBI/SLC27A6	-0.0421614558203774
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	6/379	155/9376	0.957630436632905	CCNE1/CYP11A1/PBX1/GNAI1/GNAS/HSD3B1	-0.109165952760798
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	4/379	103/9376	0.960729564259548	FXYD2/MME/COL4A2/COL1A1	-0.0822489922679113
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	6/379	156/9376	0.951491779987822	CLDN7/CLDN4/CLDN10/CLDN3/CLDN6/YWHAE	-0.125391633562552
Genetic Information Processing	Replication and repair	hsa03430	Mismatch repair	1/379	23/9376	1.07559940346449	SSBP1	0.0745011887379514
Organismal Systems	Endocrine system	hsa04614	Renin-angiotensin system	1/379	23/9376	1.07559940346449	MME	0.0745011887379514
Organismal Systems	Excretory system	hsa04964	Proximal tubule bicarbonate reclamation	1/379	23/9376	1.07559940346449	FXYD2	0.0745011887379514
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	3/379	78/9376	0.951491779987822	C1R/GNAI1/C1S	-0.0882925890475356
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	2/379	51/9376	0.970148481556211	PLA2G2A/CHPT1	-0.0438716004446733
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	4/379	107/9376	0.924814440361995	SLC2A1/PYGL/GNAS/LDHB	-0.16053371919887
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	4/379	109/9376	0.907845368061775	SLC2A1/PYGL/PRKCZ/SLC27A6	-0.198617366544877
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	3/379	82/9376	0.905077546817684	HLA-G/HSPA2/HLA-DRB5	-0.177186622057404
Genetic Information Processing	Transcription	hsa03040	Spliceosome	9/379	243/9376	0.916251343691977	LSM4/LSM3/SNRPD1/SRSF3/SNRPE/SNRPD2/LSM7/SNRPB/RBM8A	-0.271475498148012
Metabolism	Lipid metabolism	hsa00592	alpha-Linolenic acid metabolism	1/379	26/9376	0.951491779987822	PLA2G2A	-0.0508338016686669
NA	NA	hsa04081	Hormone signaling	8/379	219/9376	0.903699955422224	CGA/LEP/GAST/GNAI1/GNG12/GNAS/RAMP2/RAMP1	-0.295956798990374
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	2/379	56/9376	0.883528081417263	TUSC3/OSTC	-0.179417032667261
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	7/379	193/9376	0.897261678537739	CXCL14/GNAI1/RAC3/GNG12/PARD3/PRKCZ/CCL3L1	-0.295988754509244
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	4/379	112/9376	0.883528081417263	LAMA4/GNAI1/LAMB1/HLA-DRB5	-0.254499744417151
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	5/379	140/9376	0.883528081417263	MYL4/RPS6/GNAI1/GNG12/CDH1	-0.284970344953932
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	3/379	86/9376	0.862980916733141	FXYD2/SLC2A1/GNAS	-0.261986437334169
Metabolism	Lipid metabolism	hsa00062	Fatty acid elongation	1/379	28/9376	0.883528081417263	ECHS1	-0.126676856041808
Metabolism	Glycan biosynthesis and metabolism	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/379	28/9376	0.883528081417263	ST3GAL4	-0.126676856041808
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	9/379	250/9376	0.890596306068602	CD63/AP1M2/CLTA/ATP6V1C2/CTSV/CTSW/DEPTOR/AP1S1/ATP6V1B1	-0.359847210911594
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	4/379	115/9376	0.860479522771596	NACA/GCM1/GNAI1/GNAS	-0.308968578030394
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	5/379	143/9376	0.864992527261657	C1R/C1S/SNRPD1/HLA-DRB5/SNRPB	-0.333895673375146
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	4/379	116/9376	0.853061595851151	GNAI1/SLC1A2/GNG12/GNAS	-0.326824949703957
Organismal Systems	Nervous system	hsa04730	Long-term depression	2/379	60/9376	0.824626209322779	GNAI1/GNAS	-0.27969323201661
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	13/379	362/9376	0.888409452032828	CCNE1/RPS6/PGF/LAMA4/FGF7/GNG12/LAMB1/KIT/FLT4/COL4A2/COL1A1/YWHAE/EFNA1	-0.444405373494972
Human Diseases	Substance dependence	hsa05032	Morphine addiction	3/379	91/9376	0.815564382846705	GNAI1/GNG12/GNAS	-0.362853167314964
Metabolism	Carbohydrate metabolism	hsa00053	Ascorbate and aldarate metabolism	1/379	31/9376	0.798025363860754	ALDH7A1	-0.231176887074507
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	1/379	31/9376	0.798025363860754	SEC11A	-0.231176887074507
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	7/379	204/9376	0.848879921361685	RPS6/CAV1/MMP2/CD63/CTTN/ACTG1/COL1A1	-0.447879943278823
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	7/379	205/9376	0.844739043696506	CCNE1/HLA-G/SKP2/RANBP1/PSMC1/CDC20/YWHAE	-0.461304003319284
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	6/379	178/9376	0.833891672348878	SERPINF1/RAC3/LGR4/APCDD1/RBX1/CBY1	-0.459209736096312
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	3/379	93/9376	0.798025363860754	CGA/MMP2/GNAS	-0.401745033340614
Metabolism	Carbohydrate metabolism	hsa00052	Galactose metabolism	1/379	32/9376	0.773087071240106	AKR1B1	-0.263890768876582
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/379	32/9376	0.773087071240106	BIRC5	-0.263890768876582
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	2/379	65/9376	0.761193423990258	AKR1B1/ALDH7A1	-0.396516422993094
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	2/379	65/9376	0.761193423990258	CGA/KISS1	-0.396516422993094
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	8/379	238/9376	0.831555841333895	PLA2G2A/PGF/RAC3/FGF7/GNG12/KIT/FLT4/EFNA1	-0.540225698443284
Genetic Information Processing	Transcription	hsa03020	RNA polymerase	1/379	34/9376	0.727611361167158	POLR2L	-0.32656143775245
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/379	34/9376	0.727611361167158	RBX1	-0.32656143775245
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	3/379	97/9376	0.765117101433507	GNAI1/GNG12/GNAS	-0.477246838801114
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	3/379	98/9376	0.75730978407194	CYP11A1/GNAS/HSD3B1	-0.495672134702689
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	5/379	157/9376	0.787859435658706	ARG2/SLC2A1/PPARG/PBX1/GULP1	-0.550158746087485
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	5/379	157/9376	0.787859435658706	CCNE1/CCNB1/HLA-G/SLC25A5/CCNB2	-0.550158746087485
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	2/379	68/9376	0.727611361167158	JUP/KIT	-0.462670320810282
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	5/379	158/9376	0.782872983534284	RPS6/SKP2/ATP6V1C2/DEPTOR/ATP6V1B1	-0.564911530535138
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/379	36/9376	0.687188507768983	PYGL	-0.385937425312386
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/379	36/9376	0.687188507768983	ST6GALNAC1	-0.385937425312386
Genetic Information Processing	Replication and repair	hsa03030	DNA replication	1/379	36/9376	0.687188507768983	SSBP1	-0.385937425312386
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	2/379	69/9376	0.71706626897633	FCER1G/RAC3	-0.484128665252028
Organismal Systems	Endocrine system	hsa04924	Renin secretion	2/379	69/9376	0.71706626897633	GNAI1/GNAS	-0.484128665252028
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	2/379	70/9376	0.706822465133811	LEP/SLC2A1	-0.505306131015172
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	3/379	101/9376	0.734815434050001	GNAI1/KIT/GNAS	-0.549931193557417
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/379	71/9376	0.696867219146011	CGA/ELF5	-0.526211423814042
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	4/379	133/9376	0.744023647509275	CCNB1/BNIP3/SKP2/CCNB2	-0.610204734912672
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/379	103/9376	0.720547173194661	GNAI1/GNAS/CCL3L1	-0.585293057175892
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	3/379	104/9376	0.713618834990867	PLA2G2A/PHOSPHO1/CHPT1	-0.602741080898518
Human Diseases	Cancer: specific types	hsa05218	Melanoma	2/379	73/9376	0.677774966566668	FGF7/CDH1	-0.567238343319739
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	3/379	105/9376	0.706822465133811	BNIP3/UBA52/RPS27A	-0.620038177088912
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	4/379	138/9376	0.71706626897633	RPS6/PYGL/PRKCZ/SH2B2	-0.687213486358971
Genetic Information Processing	Replication and repair	hsa03440	Homologous recombination	1/379	41/9376	0.60338503121179	SSBP1	-0.52234837888424
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	3/379	108/9376	0.687188507768983	RAN/SAP18/RBM8A	-0.671054739682726
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/379	42/9376	0.589018720944842	CP	-0.547859465287329
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	2/379	78/9376	0.634327853325215	IMPA2/ISYNA1	-0.665580814228633
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/379	43/9376	0.575320611155427	PLA2G2A	-0.572850321955679
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	4/379	148/9376	0.668615845396848	FGF7/KIT/FLT4/HEY1	-0.833998339898725
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/379	47/9376	0.52635715488688	PRKCZ	-0.668095807719296
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	4/379	150/9376	0.659700967458223	CCNE1/FGF7/JUP/CDH1	-0.862295265838433
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	9/379	300/9376	0.742163588390501	PGF/DUSP9/STMN1/RAC3/FGF7/GNG12/KIT/FLT4/EFNA1	-0.931566827161696
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/379	48/9376	0.515391380826737	FXYD2	-0.690834260055054
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	2/379	87/9376	0.568707730567434	RAC3/BIRC5	-0.829474810020988
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/379	50/9376	0.494775725593668	HLA-DRB5	-0.735153261634193
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	4/379	154/9376	0.642565877394373	MYL6/GNAI1/ACTG1/GNAS	-0.917910197533152
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/379	89/9376	0.555927781565919	GNAI1/GNG12	-0.863907546373515
Human Diseases	Substance dependence	hsa05034	Alcoholism	5/379	191/9376	0.647612206274434	GNAI1/MAOA/GNG12/SLC18A2/GNAS	-1.00984412410716
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	7/379	253/9376	0.684472347659224	BNIP3/UBA52/ARPC1A/CTTN/RPS27A/ACTG1/RBX1	-1.04420371077506
Organismal Systems	Digestive system	hsa04970	Salivary secretion	2/379	93/9376	0.532016909240503	FXYD2/GNAS	-0.930858874133084
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/379	55/9376	0.449796114176061	B4GALNT1	-0.839904923288005
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/379	56/9376	0.441764040708632	BNIP3	-0.859924353981274
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	6/379	227/9376	0.6538886241326	HLA-G/GNAI1/RAC3/GNG12/GNAS/CCL3L1	-1.08342379959097
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/379	57/9376	0.43401379438041	ECHS1	-0.879660318707499
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	3/379	133/9376	0.558017735631956	HLA-G/FCER1G/RAC3	-1.05361166311086
NA	NA	hsa04082	Neuroactive ligand signaling	5/379	199/9376	0.621577544715663	GNAI1/SLC1A2/GNG12/SLC18A2/GNAS	-1.10741258451022
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/379	98/9376	0.504873189381293	MYO10/ARPC1A	-1.01125033915936
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	6/379	232/9376	0.639796196888363	ARPC1A/RAC3/ENAH/FGF7/ACTG1/GNG12	-1.14019875007887
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/379	59/9376	0.419301462367515	CDH1	-0.918322179004408
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	2/379	99/9376	0.499773460195624	MMP2/GNAS	-1.02692075561448
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	2/379	99/9376	0.499773460195624	CYP2J2/GNAS	-1.02692075561448
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/379	99/9376	0.499773460195624	RAC3/CHPT1	-1.02692075561448
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	4/379	169/9376	0.585533403069429	BNIP3/UBA52/RPS27A/DEPTOR	-1.11591264521612
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/379	60/9376	0.41231310466139	RAC3	-0.937266888833997
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	2/379	100/9376	0.494775725593668	CXCL14/CCL3L1	-1.04246197322231
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	3/379	138/9376	0.537799701732247	ARPC1A/RAC3/ACTG1	-1.12263135688889
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	5/379	205/9376	0.60338503121179	CCNE1/HLA-G/SKP2/PSMC1/HLA-DRB5	-1.17840361952116
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/379	62/9376	0.399012681930377	CRYAB	-0.974427245558474
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/379	62/9376	0.399012681930377	HEY1	-0.974427245558474
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	4/379	173/9376	0.571995058489789	SLC25A5/ACTG1/HLA-DRB5/RAB11A	-1.16617440848025
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	2/379	103/9376	0.480364782129774	SAP18/RBM8A	-1.08833712208387
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	4/379	174/9376	0.568707730567434	CRYAB/TUSC3/RBX1/OSTC	-1.17858678291843
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/379	63/9376	0.392679147296562	BMP4	-0.992658919595797
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/379	66/9376	0.374830095146718	HLA-DRB5	-1.04604790377826
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	3/379	149/9376	0.498096368047316	FCER1G/KIT/GNAS	-1.26747556411801
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	2/379	115/9376	0.430239761385798	GNAI1/GNG12	-1.26173601352225
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/379	73/9376	0.338887483283334	RAN	-1.16380892177917
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	5/379	226/9376	0.547318280523968	CGA/FXYD2/GNAI1/RAC3/GNAS	-1.41381639104617
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	2/379	120/9376	0.41231310466139	SH2B2/YWHAE	-1.3297847238668
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/379	77/9376	0.321282938697187	RAC3	-1.22736119462935
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	4/379	196/9376	0.504873189381293	HLA-G/UBA52/RPS27A/GNG12	-1.43773723900974
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/379	78/9376	0.317163926662607	HLA-DRB5	-1.24286903940973
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	2/379	122/9376	0.405553873437432	LEP/PPARG	-1.35638835388414
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/379	122/9376	0.405553873437432	GNAI1/GNAS	-1.35638835388414
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/379	80/9376	0.309234828496042	RPS6	-1.27345543464608
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	3/379	166/9376	0.447086499030422	FXYD2/SLC25A5/GNAI1	-1.4751555123482
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/379	83/9376	0.298057666020282	POLR2L	-1.31831409656673
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/379	90/9376	0.274875403107593	PPARG	-1.41865219725583
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/379	91/9376	0.271854794282235	RAC3	-1.4325312986607
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	4/379	216/9376	0.458125671845988	PPARG/HSPA2/CYP2J2/CCL3L1	-1.65361383832897
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	3/379	180/9376	0.41231310466139	HLA-G/SRSF3/HLA-DRB5	-1.63395149786426
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/379	93/9376	0.266008454620251	HLA-DRB5	-1.45997271492555
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	2/379	142/9376	0.348433609573005	PPARG/FHL2	-1.60569958138123
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	2/379	144/9376	0.343594253884491	ALDH7A1/ADH5	-1.62915387320139
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/379	98/9376	0.252436594690647	IMPA2	-1.52682854361603
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	3/379	187/9376	0.396878924272995	TXN/TRIP6/YWHAE	-1.70980886848568
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	6/379	298/9376	0.498096368047316	LEP/CXCL14/BMP7/BMP4/CCL3L1/LIFR	-1.80713153350884
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/379	105/9376	0.235607488377937	FCER1G	-1.61660592344798
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/379	109/9376	0.226961342015444	CCL3L1	-1.66610076191507
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/379	109/9376	0.226961342015444	HLA-DRB5	-1.66610076191507
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	2/379	163/9376	0.303543389934765	CCNE1/BIRC5	-1.84095729489285
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	6/379	323/9376	0.459544017579258	CCNE1/TPM1/IGF2BP1/STMN1/TRIM71/EFNA1	-2.0287181396042
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/379	117/9376	0.211442617775072	ACTG1	-1.76157270971498
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	2/379	168/9376	0.294509360472421	SLC25A5/PYGL	-1.89373682493143
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/379	168/9376	0.294509360472421	LEP/LIFR	-1.89373682493143
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	4/379	254/9376	0.389587185506825	SLC25A5/FGF7/FLT4/GNAS	-2.02419267791518
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/379	181/9376	0.27335675447164	FCER1G/HLA-DRB5	-2.02600748046846
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/379	136/9376	0.18190284029179	CCNE1	-1.97239883066469
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/379	195/9376	0.253731141330086	SLC25A5/ACTG1	-2.16134459371804
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	6/379	370/9376	0.401169507238109	CGA/LEP/GZMA/KISS1/TMEM97/GAL	-2.41209928758117
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	1/379	183/9376	0.135184624479144	RAN	-2.42480433662188