category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Genetic Information Processing	Translation	hsa03010	Ribosome	73/307	222/9376	10.0426680752414	RPS18/RPL37/RPS3A/RPS4X/RPL13/RPL29/RPL18A/RPL6/RPS6/RPL11/RPL7A/RPL37A/RPS14/RPS13/RPLP0/RPS27/RPL18/RPS7/RPL23A/RPS3/RPS2/RPS23/RPL3/RPL32/RPL13A/RPL10A/RPS11/RPL34/RPL5/RPS12/RPS27A/RPL26/RPL30/RPL39/RPL14/RPL36/RPS15/RPL27A/RPL10/RPL35A/RPS9/RPL24/RPS29/RPL8/RPL31/RPL21/RPS8/RPLP1/RPS24/RPL23/RPS5/RPS16/RPL15/RPL7/RPS15A/RPL19/RPL9/RPL28/RPL22/RPL38/RPSA/RPL12/RPS20/RPS25/RPS19/RPS28/RPL4/RPL27/RPLP2/RPL35/UBA52/RPL41/RPS21	25.0866544556427
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	73/307	238/9376	9.36753072564531	RPS18/RPL37/RPS3A/RPS4X/RPL13/RPL29/RPL18A/RPL6/RPS6/RPL11/RPL7A/RPL37A/RPS14/RPS13/RPLP0/RPS27/RPL18/RPS7/RPL23A/RPS3/RPS2/RPS23/RPL3/RPL32/RPL13A/RPL10A/RPS11/RPL34/RPL5/RPS12/RPS27A/RPL26/RPL30/RPL39/RPL14/RPL36/RPS15/RPL27A/RPL10/RPL35A/RPS9/RPL24/RPS29/RPL8/RPL31/RPL21/RPS8/RPLP1/RPS24/RPL23/RPS5/RPS16/RPL15/RPL7/RPS15A/RPL19/RPL9/RPL28/RPL22/RPL38/RPSA/RPL12/RPS20/RPS25/RPS19/RPS28/RPL4/RPL27/RPLP2/RPL35/UBA52/RPL41/RPS21	24.0566606757377
NA	NA	hsa04382	Cornified envelope formation	24/307	217/9376	3.37777510920308	KRT19/KRT18/KRT7/KRT8/S100A12/S100A9/DSP/CLDN10/CLDN7/S100A8/COL4A2/COL4A1/S100A13/KRT23/DSG2/CLDN4/S100A16/PADI1/PRSS8/CLDN3/S100A1/JUP/CLDN6/PKP2	6.52006220117808
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	19/307	158/9376	3.67261782047582	CDKN1C/CCNB1/CCNE1/MAD2L1/CDC20/CCNA2/PTTG1/CDK7/CCNB2/AURKB/CDK1/SFN/CDT1/SKP2/MCM7/ORC6/WEE1/NDC80/CDCA5	6.23335952183465
NA	NA	hsa04518	Integrin signaling	15/307	154/9376	2.97474512458226	PGF/FERMT2/COL1A1/COL4A2/RAC3/COL4A1/PARVA/ERBB2/LAMA4/CDH1/FERMT1/PTK2/LAMB1/FLNB/LAMA2	4.54604757897202
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	19/307	233/9376	2.49044470229691	TPM1/TPM2/MYL4/VCAN/DSP/COL1A1/COL4A2/COL4A1/DSG2/CSRP2/PDLIM1/DSC2/JUP/COL27A1/FHL2/NID1/PKP2/SYNE2/LAMA2	4.23862107646747
NA	NA	hsa03272	Virion - Hepatitis viruses	7/307	48/9376	4.45385450597177	EPCAM/CLDN10/CLDN7/CLDN4/LDLR/CLDN3/CLDN6	4.41372747175361
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	6/307	41/9376	4.469373162787	GCSH/ALAS2/PHGDH/ALDH7A1/GLDC/PSAT1	4.09600904408747
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	8/307	75/9376	3.25767643865364	CCNB1/CCNE1/RRM2/PERP/CCNB2/CDK1/SFN/IGFBP3	3.61162487171933
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	9/307	93/9376	2.9555532205527	CCNE1/COL4A2/COL4A1/LAMA4/CKS1B/SKP2/PTK2/LAMB1/LAMA2	3.48692064495611
NA	NA	hsa04519	Cadherin signaling	24/307	404/9376	1.81429999677492	KRT19/KRT18/KRT7/KRT8/DSP/LIMA1/DSC3/TEAD4/RAC3/MYO1B/KRT23/DSG2/ERBB2/TCF7L2/CDH1/NCKAP1/ENAH/PTK2/DSC2/JUP/AMOTL1/CYFIP2/WNT7A/PKP2	3.07826219140002
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	12/307	160/9376	2.29055374592834	HLA-G/VCAN/HLA-DRB5/CLDN10/JAM3/CLDN7/CLDN4/SELL/CDH1/CLDN3/CNTNAP2/CLDN6	3.02928391623617
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	7/307	75/9376	2.85046688382193	GAPDH/PHGDH/PSAT1/TKT/ALDOA/GPT2/ASNS	2.9602081624636
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	6/307	59/9376	3.10583558769944	RRM2/GPX3/GSTP1/PRDX6/GSTA4/GPX8	2.98529699546177
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	9/307	116/9376	2.3695383578569	MMP2/CLDN10/JAM3/CLDN7/GNAI1/CLDN4/CLDN3/PTK2/CLDN6	2.73069268343502
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	13/307	203/9376	1.95580943823109	PGF/CAV1/COL1A1/COL4A2/RAC3/COL4A1/PARVA/ERBB2/LAMA4/PTK2/LAMB1/FLNB/LAMA2	2.53302083411534
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	8/307	103/9376	2.37209449416527	CD1C/COL1A1/COL4A2/COL4A1/LAMA4/PTK2/LAMB1/LAMA2	2.57612913345932
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	7/307	86/9376	2.48587228240285	DSP/DSG2/TCF7L2/DSC2/JUP/PKP2/LAMA2	2.54681837755632
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	11/307	170/9376	1.97616401609504	CLDN10/JAM3/CD1C/CLDN7/ERBB2/CLDN4/CLDN3/PARD6B/AMOTL1/CLDN6/TUBA1C	2.36312608881614
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	7/307	89/9376	2.4020788346814	COL1A1/COL4A2/COL4A1/HMMR/LAMA4/LAMB1/LAMA2	2.44514624160776
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	6/307	70/9376	2.61777570963239	HLA-G/CAV1/HLA-DRB5/RAC3/CD55/LAMA2	2.49954483514573
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	5/307	52/9376	2.93660736657479	CGA/CYP11A1/LDLR/CYP2J2/HSD3B1	2.57642345325513
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	12/307	200/9376	1.83244299674267	RPS3/GAPDH/CLDN10/CLDN7/MYO1B/CLDN4/CLDN3/NCKAP1/CYFIP2/CLDN6/TUBA1C/BAIAP2L1	2.18936375657208
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	10/307	157/9376	1.94526857403681	HLA-G/CCNB1/CCNE1/CCNA2/CALM1/CCNB2/CDK1/SLC25A4/IGFBP3/MYBL2	2.19754746134765
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	8/307	116/9376	2.10625631809502	GCSH/GAPDH/PHGDH/GLDC/PSAT1/TKT/ALDOA/GPT2	2.20574036243349
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	4/307	39/9376	3.13238119101311	GCSH/TYMS/ALDH7A1/GLDC	2.45509664155679
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	12/307	214/9376	1.71256354835764	HLA-G/CCNB1/CALM1/GNAI1/RAC3/CCNB2/CDK1/APOBEC3B/AP1M2/WEE1/PTK2/GNG12	1.94003904204365
Cellular Processes	Cell motility	hsa04814	Motor proteins	11/307	194/9376	1.73169011719668	TPM1/TPM2/MYL4/KIF2C/MYO1B/KIF11/CENPE/KIF14/KIF4A/TUBA1C/KIF23	1.89467417189795
Metabolism	Lipid metabolism	hsa00591	Linoleic acid metabolism	3/307	30/9376	3.05407166123778	PLA2G2A/PLA2G10/CYP2J2	2.07318689509618
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	3/307	30/9376	3.05407166123778	ABCG2/TYMS/FOLR1	2.07318689509618
NA	NA	hsa04981	Folate transport and metabolism	3/307	31/9376	2.9555532205527	ABCG2/TYMS/FOLR1	2.00648519155021
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	4/307	50/9376	2.44325732899023	HBA2/HBA1/GYPB/GYPA	1.88259193204013
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	8/307	138/9376	1.77047632535524	CCNB1/CCNE1/MAD2L1/CDC20/CALM1/PTTG1/CCNB2/CDK1	1.6775867519329
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	5/307	75/9376	2.03604777415852	BIRC5/TOP2A/GSTP1/ERBB2/GSTA4	1.65737474395215
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	4/307	54/9376	2.26227530462058	PHGDH/LDHB/ADI1/PSAT1	1.71147886842194
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	10/307	193/9376	1.58242054986414	CXCL14/CCL3L1/GNAI1/RAC3/CCL4L2/XCR1/CCL3L3/PTK2/CX3CR1/GNG12	1.50417434578193
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	6/307	100/9376	1.83244299674267	CXCL14/CCL3L1/CCL4L2/XCR1/CCL3L3/CX3CR1	1.53974661849312
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	11/307	224/9376	1.49976733364356	HLA-G/CCNE1/HLA-DRB5/MAD2L1/SLC2A1/CDC20/CCNA2/PTTG1/CCNB2/SLC25A4/MSX2	1.3928648998098
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	3/307	37/9376	2.47627431992253	HBA2/HBA1/LAMA4	1.65536155428287
Metabolism	Metabolism of cofactors and vitamins	hsa00785	Lipoic acid metabolism	2/307	19/9376	3.21481227498714	GCSH/GLDC	1.77795404916051
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	8/307	157/9376	1.55621485922944	BIRC5/TEAD4/TCF7L2/CDH1/PARD6B/ID1/WNT7A/RASSF6	1.29308070260242
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	3/307	41/9376	2.2346865813935	MMP2/ERBB2/CDH1	1.45769485342379
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	7/307	134/9376	1.59541056930332	CALD1/CALM1/PLA2G2A/PPP1R14A/RAMP1/PLA2G10/RAMP2	1.27720638720901
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	4/307	63/9376	1.93909311824621	PTGDS/PLA2G2A/PLA2G10/CYP2J2	1.3759709222399
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	6/307	110/9376	1.66585726976606	RPS6/GAPDH/SLC2A1/LDHB/ERBB2/ALDOA	1.29242831855051
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	6/307	110/9376	1.66585726976606	CCNB1/MAD2L1/CCNA2/GNAI1/CCNB2/CDK1	1.29242831855051
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	5/307	87/9376	1.75521359841252	TPM1/TPM2/MYL4/COX8C/COX4I1	1.30202724254637
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	6/307	112/9376	1.63610981852024	HLA-DRB5/GNAI1/LAMA4/LDLR/LAMB1/LAMA2	1.24599690113514
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	6/307	115/9376	1.59342869281971	NACA/GCM1/GNAI1/GATA3/MMP15/PDE4C	1.17804978429059
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	4/307	67/9376	1.82332636491808	GAPDH/LDHB/ALDH7A1/ALDOA	1.24432272871658
NA	NA	hsa04081	Hormone signaling	10/307	219/9376	1.39455326997159	CGA/GAST/LEP/DIO2/GNAI1/RAMP1/SLC16A2/GHR/RAMP2/GNG12	1.08699168611875
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	4/307	68/9376	1.79651274190458	CCNA2/TCF7L2/JUP/DUSP6	1.21281377696394
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	7/307	142/9376	1.50552828370877	MMP2/CAV1/GSTP1/CALM1/RAC3/GSTA4/PTK2	1.11678563981956
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	5/307	93/9376	1.64197401141816	RAC3/ERBB2/ARHGAP29/TCF7L2/CDH1	1.1446952250712
Metabolism	Lipid metabolism	hsa00592	alpha-Linolenic acid metabolism	2/307	26/9376	2.34928589325983	PLA2G2A/PLA2G10	1.2675350385154
Environmental Information Processing	Signal transduction	hsa04392	Hippo signaling pathway - multiple species	2/307	29/9376	2.10625631809502	TEAD4/RASSF6	1.09772553474847
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	7/307	155/9376	1.37925816959126	CCNE1/CYP11A1/GNAI1/TCF7L2/LDLR/HSD3B1/WNT7A	0.875965310368355
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	5/307	103/9376	1.48255905885329	COL1A1/COL4A2/COL4A1/COL27A1/COL21A1	0.906012272050518
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	6/307	130/9376	1.4095715359559	MMP2/COL1A1/GNAI1/COL4A2/COL4A1/GNG12	0.865166357680307
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	9/307	212/9376	1.29653985618585	PGF/CALM1/GNAI1/EFNA1/RAC3/CDH1/ENAH/PARD6B/ID1	0.803495757110788
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	3/307	54/9376	1.69670647846544	CGA/HLA-G/HLA-DRB5	0.94464211651885
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	5/307	106/9376	1.4405998402065	CCNE1/GSTP1/ERBB2/TCF7L2/FOLR1	0.839329573988493
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	2/307	31/9376	1.9703688137018	TKT/ALDOA	0.995641864701853
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	2/307	31/9376	1.9703688137018	GCSH/GLDC	0.995641864701853
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	4/307	82/9376	1.48979105426233	RRM2/GSTP1/TK1/GSTA4	0.819580403781139
Human Diseases	Immune disease	hsa05310	Asthma	2/307	32/9376	1.90879478827362	HLA-DRB5/FCER1A	0.947435224116736
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	13/307	333/9376	1.19228022811085	HLA-G/CCNE1/CCNA2/COL1A1/COL4A2/COL4A1/LAMA4/TCF7L2/PTK2/LAMB1/PARD6B/WNT7A/LAMA2	0.657318120835438
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	14/307	362/9376	1.18113268666655	RPS6/CCNE1/PGF/COL1A1/EFNA1/COL4A2/COL4A1/ERBB2/LAMA4/GHR/PTK2/LAMB1/GNG12/LAMA2	0.646647290618779
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	6/307	139/9376	1.31830431420336	KRT19/KRT18/MMP2/CALM1/GNAI1/KRT23	0.695600007905336
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	3/307	59/9376	1.55291779384972	RRM2/TYMS/TK1	0.78383319113729
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	3/307	59/9376	1.55291779384972	ERBB2/TCF7L2/CDH1	0.78383319113729
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	6/307	140/9376	1.30888785481619	RPS6/MYL4/CALM1/GNAI1/CDH1/GNG12	0.677482393648896
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	2/307	35/9376	1.74518380642159	AKR1B1/ALDOA	0.812598225870182
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	9/307	227/9376	1.21086541634978	HLA-G/CALM1/CCL3L1/GNAI1/RAC3/CCL4L2/CCL3L3/PTK2/GNG12	0.591706850726851
Metabolism	Amino acid metabolism	hsa00250	Alanine, aspartate and glutamate metabolism	2/307	37/9376	1.65084954661502	GPT2/ASNS	0.729804279969782
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	2/307	37/9376	1.65084954661502	TCF7L2/CDH1	0.729804279969782
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	3/307	65/9376	1.4095715359559	CYP11A1/LDLR/HSD3B1	0.609625895831117
Human Diseases	Immune disease	hsa05330	Allograft rejection	2/307	39/9376	1.56619059550656	HLA-G/HLA-DRB5	0.65187811417937
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	6/307	150/9376	1.22162866449511	CCNE1/ERBB2/TCF7L2/CDH1/JUP/WNT7A	0.503431004706215
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	7/307	184/9376	1.16187508851437	GNAI1/EFNA1/RAC3/ENAH/PTK2/PARD6B/EPHB4	0.407998952006735
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	4/307	98/9376	1.24655986172971	CALM1/CYP11A1/LDLR/HSD3B1	0.451422661101142
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	6/307	156/9376	1.17464294662992	CLDN10/CLDN7/CLDN4/LDLR/CLDN3/CLDN6	0.404690504089237
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	4/307	99/9376	1.23396834797486	KRT19/KRT18/HLA-DRB5/KRT23	0.430572265922808
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	3/307	71/9376	1.29045281460751	SLC2A1/LDHB/ERBB2	0.451982583210346
Metabolism	Amino acid metabolism	hsa00360	Phenylalanine metabolism	1/307	16/9376	1.90879478827362	MIF	0.66936503032768
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	2/307	43/9376	1.42049844708734	PLA2G2A/PLA2G10	0.508467402867208
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	4/307	100/9376	1.22162866449511	GYPA/HLA-DRB5/CD1C/CD55	0.409940365950352
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	4/307	101/9376	1.20953333118328	CALM1/GNAI1/TCF7L2/WNT7A	0.389521980999248
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	4/307	101/9376	1.20953333118328	MMP2/COL1A1/COL4A2/COL4A1	0.389521980999248
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	2/307	44/9376	1.38821439147172	HLA-G/HLA-DRB5	0.474882022850122
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	2/307	45/9376	1.35736518277235	ABCG2/ABCA7	0.442109172259209
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	2/307	45/9376	1.35736518277235	HLA-G/HLA-DRB5	0.442109172259209
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	3/307	75/9376	1.22162866449511	CGA/GPX3/GPX8	0.354541325440697
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/307	46/9376	1.32785724401643	ALAS2/CP	0.410107774913984
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	3/307	76/9376	1.20555460312018	GAST/CALM1/GNAI1	0.331030228280528
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	2/307	47/9376	1.29960496222884	LDHB/ALDH7A1	0.378839722256693
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	3/307	77/9376	1.1898980498329	RAC3/ERBB2/RALBP1	0.307838453422716
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	3/307	78/9376	1.17464294662992	CAV1/CDH1/PTK2	0.284956590434453
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	2/307	49/9376	1.24655986172971	GNAI1/SLC18A2	0.318364441158471
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	7/307	201/9376	1.06360704620221	CCNA2/MYCN/IGFBP3/ETV4/PTK2/JUP/DUSP6	0.167716328030021
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	3/307	80/9376	1.14527687296417	RPS6/ERBB2/NRG1	0.240086944310971
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	2/307	50/9376	1.22162866449511	CKB/ALDH7A1	0.289093515970051
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	5/307	142/9376	1.07537734550626	RPS27A/UBE2C/CDC20/UBA52/SKP2	0.16651953954293
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	2/307	51/9376	1.19767516126972	PLA2G2A/PLA2G10	0.260428131242477
Metabolism	Glycan biosynthesis and metabolism	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/307	21/9376	1.45431983868466	DSEL	0.383463982101594
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	7/307	204/9376	1.047965766111	RPS6/MMP2/CAV1/COL1A1/ERBB2/PTK2/WNT7A	0.127435248775584
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	3/307	82/9376	1.11734329069675	HLA-G/HLA-DRB5/HSPA2	0.19635365067068
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	7/307	205/9376	1.04285373798363	MMP2/GAPDH/SLC2A1/COL1A1/SLC25A4/COX8C/COX4I1	0.114138567787862
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	5/307	144/9376	1.0604415490409	ID4/DLX5/LIFR/ID1/WNT7A	0.134475776086961
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	9/307	268/9376	1.02562108026642	RPS27A/CALM1/UBA52/GNAI1/SLC18A2/SLC25A4/COX8C/COX4I1/TUBA1C	0.078293993970572
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/307	22/9376	1.38821439147172	ALDH7A1	0.335397185333844
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	8/307	238/9376	1.02657870965976	PGF/CALM1/EFNA1/PLA2G2A/RAC3/PLA2G10/RALBP1/GNG12	0.0764138215261206
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	4/307	115/9376	1.06228579521314	GNAI1/SLC18A2/CYP2J2/GNG12	0.123647151718534
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	6/307	178/9376	1.0294623577206	RAC3/NOTUM/TCF7L2/WNT7A/LGR4/RNF43	0.0730139630610492
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	3/307	85/9376	1.07790764514275	RRM2/TYMS/TK1	0.13274966544713
Genetic Information Processing	Replication and repair	hsa03460	Fanconi anemia pathway	2/307	54/9376	1.13113765231029	FANCI/UBE2T	0.177805364615756
Metabolism	Amino acid metabolism	hsa00220	Arginine biosynthesis	1/307	23/9376	1.32785724401643	GPT2	0.289633211410902
Organismal Systems	Endocrine system	hsa04614	Renin-angiotensin system	1/307	23/9376	1.32785724401643	ENPEP	0.289633211410902
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	3/307	86/9376	1.06537383531551	ERBB2/NRG1/PTK2	0.112052218191746
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	3/307	87/9376	1.05312815904751	BIRC5/RAC3/TCF7L2	0.0915956897116303
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	2/307	56/9376	1.09073987901349	TUSC3/MGAT3	0.125302396763606
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	2/307	56/9376	1.09073987901349	EEF1A1/BNIP3	0.125302396763606
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	3/307	88/9376	1.04116079360379	TFPI/SERPINB2/CD55	0.0713738456465031
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	3/307	89/9376	1.0294623577206	GNAI1/CDK1/TUBA1C	0.0513806866400648
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	3/307	89/9376	1.0294623577206	GNAI1/SLC38A1/GNG12	0.0513806866400648
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	7/307	216/9376	0.989745445771504	CALM1/CCL3L1/HSPA2/LDLR/CCL3L3/CYP2J2/PTK2	-0.0280524663320032
Organismal Systems	Digestive system	hsa04976	Bile secretion	3/307	90/9376	1.01802388707926	ABCG2/SLC2A1/LDLR	0.0316104368603665
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	4/307	122/9376	1.00133497089763	GNAI1/IGFBP3/GHR/PTK2	0.00273062518155522
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	5/307	154/9376	0.991581708194086	TPM1/TPM2/MYL4/CALM1/GNAI1	-0.0193796934130681
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	3/307	91/9376	1.00683681139707	RAC3/LILRA3/LILRA5	0.0120575332042047
Human Diseases	Substance dependence	hsa05032	Morphine addiction	3/307	91/9376	1.00683681139707	GNAI1/PDE4C/GNG12	0.0120575332042047
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/307	59/9376	1.03527852923315	CGA/GNAI1	0.0500119230291291
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	2/307	60/9376	1.01802388707926	RAC3/PTK2	0.0257682228724796
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	3/307	93/9376	0.985184406850898	CGA/MMP2/CALM1	-0.0264174848712489
Metabolism	Lipid metabolism	hsa01040	Biosynthesis of unsaturated fatty acids	1/307	27/9376	1.13113765231029	ELOVL6	0.125545696854257
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	3/307	95/9376	0.964443682496143	HLA-DRB5/CCL3L1/CCL3L3	-0.0640849894153272
Metabolism	Lipid metabolism	hsa00062	Fatty acid elongation	1/307	28/9376	1.09073987901349	ELOVL6	0.0884693801951017
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	1/307	28/9376	1.09073987901349	AKR1B1	0.0884693801951017
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	2/307	63/9376	0.969546559123106	TCF7L2/WNT7A	-0.0446207605130926
Organismal Systems	Sensory system	hsa04744	Phototransduction	1/307	29/9376	1.05312815904751	CALM1	0.0527184666398643
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	3/307	97/9376	0.944558245743645	CALM1/GNAI1/GNG12	-0.100982790665811
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	6/307	196/9376	0.934919896297281	HLA-G/RPS27A/CALM1/UBA52/TCF7L2/GNG12	-0.16940649473314
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	2/307	65/9376	0.939714357303934	ALDH7A1/AKR1B1	-0.0897320387476854
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	3/307	99/9376	0.925476260981147	MMP2/ERBB2/PTK2	-0.137146137296465
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	3/307	99/9376	0.925476260981147	TPM1/TPM2/LAMA2	-0.137146137296465
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	4/307	133/9376	0.918517792853469	CCNB1/CCNB2/BNIP3/SKP2	-0.174123445951636
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	4/307	133/9376	0.918517792853469	CALM1/GNAI1/SLC18A2/GNG12	-0.174123445951636
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	2/307	66/9376	0.925476260981147	CYP11A1/HSD3B1	-0.111780716367084
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	2/307	66/9376	0.925476260981147	HLA-DRB5/GATA3	-0.111780716367084
Metabolism	Carbohydrate metabolism	hsa00053	Ascorbate and aldarate metabolism	1/307	31/9376	0.985184406850898	ALDH7A1	-0.0152014621465037
Metabolism	Metabolism of other amino acids	hsa00410	beta-Alanine metabolism	1/307	31/9376	0.985184406850898	ALDH7A1	-0.0152014621465037
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	9/307	298/9376	0.922370635944297	LEP/CXCL14/CCL3L1/CCL4L2/XCR1/CCL3L3/LIFR/GHR/CX3CR1	-0.250561416876644
Metabolism	Carbohydrate metabolism	hsa00052	Galactose metabolism	1/307	32/9376	0.954397394136808	AKR1B1	-0.0475415524646391
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/307	32/9376	0.954397394136808	LDHB	-0.0475415524646391
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/307	32/9376	0.954397394136808	BIRC5	-0.0475415524646391
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/307	103/9376	0.889535435311976	CCL3L1/GNAI1/CCL3L3	-0.207398968888686
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	2/307	69/9376	0.885238162677619	FCER1A/RAC3	-0.17603227674288
Organismal Systems	Endocrine system	hsa04924	Renin secretion	2/307	69/9376	0.885238162677619	CALM1/GNAI1	-0.17603227674288
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	2/307	69/9376	0.885238162677619	CALM1/SLC18A2	-0.17603227674288
Metabolism	Global and overview maps	hsa01210	2-Oxocarboxylic acid metabolism	1/307	33/9376	0.925476260981147	GPT2	-0.0789011906219398
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	6/307	205/9376	0.893874632557401	HLA-G/CCNE1/CDC20/CCNA2/CDK1/SKP2	-0.28265906349838
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	2/307	70/9376	0.872591903210796	LEP/SLC2A1	-0.196851917351119
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	2/307	70/9376	0.872591903210796	GSTP1/GSTA4	-0.196851917351119
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	3/307	105/9376	0.872591903210796	RPS27A/UBA52/BNIP3	-0.24154803692097
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	3/307	105/9376	0.872591903210796	TPM1/TPM2/LAMA2	-0.24154803692097
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	3/307	107/9376	0.856281774178818	SLC2A1/CALM1/LDHB	-0.275082156308263
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	2/307	73/9376	0.836731961982955	GSTP1/GSTA4	-0.25764766948141
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	3/307	109/9376	0.840570181992051	CCL3L1/CCL4L2/CCL3L3	-0.308026685579406
Metabolism	Carbohydrate metabolism	hsa00040	Pentose and glucuronate interconversions	1/307	36/9376	0.848353239232718	AKR1B1	-0.167720471760801
Genetic Information Processing	Replication and repair	hsa03030	DNA replication	1/307	36/9376	0.848353239232718	MCM7	-0.167720471760801
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	3/307	110/9376	0.832928634883032	ID4/LRRC32/ID1	-0.324285358590322
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/307	37/9376	0.82542477330751	MIF	-0.195752994343308
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/307	38/9376	0.803703068746786	NNMT	-0.223076333996392
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/307	38/9376	0.803703068746786	SFN	-0.223076333996392
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	2/307	78/9376	0.783095297753278	CALM1/GNAI1	-0.353913087211036
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	2/307	78/9376	0.783095297753278	HLA-DRB5/EEF1A1	-0.353913087211036
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	2/307	79/9376	0.77318269904754	GSTP1/GSTA4	-0.372471830558406
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	9/307	323/9376	0.850979719849538	TPM1/CCNE1/STMN1/EFNA1/IGF2BP1/ERBB2/CDCA5/TRIM71/KIF23	-0.50144753583283
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	3/307	116/9376	0.789846119285634	GNAI1/SLC38A1/GNG12	-0.419021242574175
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/307	42/9376	0.72715991934233	ALDH7A1	-0.326042369849505
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/307	42/9376	0.72715991934233	CP	-0.326042369849505
Human Diseases	Substance dependence	hsa05034	Alcoholism	5/307	191/9376	0.799495199276907	CALM1/GNAI1/SLC18A2/PKIA/GNG12	-0.515082747700708
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	6/307	226/9376	0.810815485284368	CGA/CALM1/GNAI1/RAC3/FFAR2/PDE4C	-0.529668789192604
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/307	43/9376	0.710249223543671	ALDH7A1	-0.350367107902553
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	3/307	122/9376	0.751001228173226	SLC2A1/DIO2/SLC16A2	-0.509316208863691
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/307	44/9376	0.69410719573586	TUSC3	-0.37418240244407
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	1/307	44/9376	0.69410719573586	CDK7	-0.37418240244407
Genetic Information Processing	Replication and repair	hsa03410	Base excision repair	1/307	44/9376	0.69410719573586	HMGB1	-0.37418240244407
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	6/307	232/9376	0.789846119285634	RAC3/NCKAP1/ENAH/PTK2/CYFIP2/GNG12	-0.596332422987602
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	3/307	125/9376	0.732977198697068	FCER1A/GNAI1/RAC3	-0.552947805415255
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	1/307	48/9376	0.636264929424538	ALDH7A1	-0.464821975176819
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	5/307	205/9376	0.744895527131167	HLA-G/CCNE1/HLA-DRB5/CCNA2/SKP2	-0.679456694784621
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	4/307	169/9376	0.722857197926103	RPS27A/UBA52/BNIP3/HMGB1	-0.668902792985727
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/307	50/9376	0.610814332247557	HLA-DRB5	-0.507655692064987
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	4/307	170/9376	0.718605096761832	GSTP1/TCF7L2/GSTA4/WNT7A	-0.681208922002783
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	2/307	93/9376	0.656789604567266	HLA-DRB5/GATA3	-0.611973839842475
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/307	94/9376	0.649802481114422	S100A9/S100A8	-0.627814489347032
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/307	52/9376	0.587321473314959	LDLR	-0.549019203973503
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	6/307	248/9376	0.738888305138174	RPS3/GAPDH/TCF7L2/NCKAP1/CYFIP2/TUBA1C	-0.766724733892794
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	3/307	137/9376	0.668774816329442	BIRC5/CTSV/TUBA1C	-0.718532265198126
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	6/307	250/9376	0.732977198697068	HLA-G/CAV1/LDLR/AGAP1/PARD6B/FOLR1	-0.787323555091761
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	2/307	99/9376	0.616984173987431	CALM1/CYP2J2	-0.704864540515737
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/307	99/9376	0.616984173987431	RAC3/SLC44A2	-0.704864540515737
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	3/307	142/9376	0.645226407303757	LILRA3/LILRA5/FHL2	-0.783746560733705
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/307	57/9376	0.53580204583119	ELOVL6	-0.646742079986005
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	2/307	102/9376	0.59883758063486	PLA2G2A/PLA2G10	-0.749483207818916
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	2/307	104/9376	0.587321473314959	PLA2G2A/PLA2G10	-0.778604580894664
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/307	60/9376	0.509011943539631	GNAI1	-0.701951227887669
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	7/307	300/9376	0.712616720955483	PGF/STMN1/EFNA1/RAC3/ERBB2/DUSP6/GNG12	-0.930786347414188
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	3/307	148/9376	0.619068579980632	ERBB2/TCF7L2/WNT7A	-0.859407195235498
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/307	61/9376	0.500667485448817	MT1E	-0.719844116504735
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	5/307	227/9376	0.672703009083213	SLC25A4/GSTA4/COX8C/PTK2/COX4I1	-0.91842405976378
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/307	62/9376	0.492592203425449	CRYAB	-0.737496543205377
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/307	109/9376	0.560380121328034	HLA-DRB5/GATA3	-0.849368429533017
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	2/307	109/9376	0.560380121328034	SLC2A1/SLC27A6	-0.849368429533017
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/307	63/9376	0.484773279561553	ALDH7A1	-0.75491660188959
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/307	63/9376	0.484773279561553	CDK7	-0.75491660188959
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/307	65/9376	0.469857178651967	CGA	-0.789089973326488
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	3/307	155/9376	0.591110644110539	HLA-G/HLA-DRB5/TUBA1C	-0.944403892272238
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	3/307	157/9376	0.583580572211042	SLC2A1/PTK2/CX3CR1	-0.96808619426063
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	3/307	157/9376	0.583580572211042	LEP/COX8C/COX4I1	-0.96808619426063
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/307	67/9376	0.45583159122952	CALM1	-0.822421275614095
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	2/307	115/9376	0.531142897606571	GNAI1/GNG12	-0.930755480853521
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	3/307	158/9376	0.579887024285655	RPS6/SKP2/WNT7A	-0.979831533469711
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/307	68/9376	0.449128185476145	ALDH1A3	-0.838787493089087
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	2/307	117/9376	0.522063531835519	MTA3/CECR2	-0.957097504202515
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/307	70/9376	0.436295951605398	SLC2A1	-0.870951105475332
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	3/307	163/9376	0.562099078755421	BIRC5/CCNE1/CCNA2	-1.03763413544264
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/307	71/9376	0.430150938202505	CGA	-0.88675970084595
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/307	71/9376	0.430150938202505	JAM3	-0.88675970084595
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/307	73/9376	0.418365980991477	APOBEC3B	-0.917856619756812
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/307	73/9376	0.418365980991477	CDH1	-0.917856619756812
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/307	73/9376	0.418365980991477	ERBB2	-0.917856619756812
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	2/307	122/9376	0.500667485448817	LEP/CCNA2	-1.02136304290894
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	3/307	166/9376	0.551940661669479	CALM1/GNAI1/SLC25A4	-1.07160538442518
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	3/307	168/9376	0.545369939506747	LEP/LIFR/GHR	-1.0939696128111
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/307	76/9376	0.401851534373393	SLC27A6	-0.96327311632257
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/307	76/9376	0.401851534373393	CALM1	-0.96327311632257
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	5/307	253/9376	0.603571474552922	RPS27A/UBA52/BNIP3/FNBP1L/PTK2	-1.17606532433059
Organismal Systems	Immune system	hsa04611	Platelet activation	2/307	126/9376	0.484773279561553	COL1A1/GNAI1	-1.07124278349505
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	2/307	128/9376	0.477198697068404	RRM2/PDE4C	-1.09570302473499
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/307	79/9376	0.38659134952377	SLC18A2	-1.00731929162287
NA	NA	hsa04517	IgSF CAM signaling	6/307	299/9376	0.612857189546044	JAM3/CDH1/CNTNAP2/PTK2/PARD6B/TUBA1C	-1.25173025621645
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	2/307	133/9376	0.459258896426735	HLA-G/RAC3	-1.15553698922939
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/307	83/9376	0.367960441112986	AURKB	-1.06409515040159
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/307	83/9376	0.367960441112986	PXMP2	-1.06409515040159
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/307	83/9376	0.367960441112986	CCL4L2	-1.06409515040159
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	3/307	180/9376	0.509011943539631	HLA-G/HLA-DRB5/CFP	-1.22372215843619
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	6/307	308/9376	0.594949024916452	GPX3/SLC25A4/GPX8/COX8C/COX4I1/TUBA1C	-1.32985536442857
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/307	86/9376	0.355124611771835	SLC2A1	-1.10533086149054
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	8/307	388/9376	0.62970549716243	GAPDH/CALM1/BACE2/SLC25A4/COX8C/WNT7A/COX4I1/TUBA1C	-1.37058735510374
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	2/307	138/9376	0.442619081338809	COX8C/COX4I1	-1.21360619937944
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	2/307	138/9376	0.442619081338809	RPS6/CALM1	-1.21360619937944
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/307	138/9376	0.442619081338809	RAC3/PTK2	-1.21360619937944
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	5/307	275/9376	0.555285756588688	CAV1/SLC25A4/COX8C/COX4I1/TUBA1C	-1.37713955991812
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	2/307	144/9376	0.424176619616359	ALDH7A1/TCF7L2	-1.28114347158297
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/307	93/9376	0.328394802283633	CALM1	-1.1975301948137
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	10/307	480/9376	0.636264929424538	RPS27A/GPX3/CALM1/UBA52/SLC25A4/GPX8/COX8C/WNT7A/COX4I1/TUBA1C	-1.50516299816463
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	3/307	195/9376	0.469857178651967	SLC25A4/HMGB1/PADI4	-1.37638623918206
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	2/307	149/9376	0.409942504864132	GNAI1/GNG12	-1.33577198311207
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	7/307	368/9376	0.580937544257187	GPX3/HNRNPA1/NRG1/GPX8/COX8C/COX4I1/TUBA1C	-1.50891091199722
NA	NA	hsa04082	Neuroactive ligand signaling	3/307	199/9376	0.460412813251927	GNAI1/SLC18A2/GNG12	-1.41550994690597
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/307	98/9376	0.311639965432427	CALM1	-1.26030780687579
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	2/307	154/9376	0.396632683277634	ALAS2/PSAT1	-1.38900787512859
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/307	154/9376	0.396632683277634	CALM1/GNAI1	-1.38900787512859
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/307	105/9376	0.290863967736932	CCL4L2	-1.34442332017932
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/307	105/9376	0.290863967736932	CALM1	-1.34442332017932
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	1/307	108/9376	0.282784413077573	EEF1A1	-1.37925227664441
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	3/307	217/9376	0.422221888650385	BIRC5/GNAI1/GSTA4	-1.58431687248222
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	2/307	168/9376	0.363579959671165	SLC25A4/HMGB1	-1.53140816150254
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	2/307	173/9376	0.353071868351189	HLA-DRB5/SLC25A4	-1.58011793443289
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	2/307	174/9376	0.351042719682504	TUSC3/CRYAB	-1.58973502823873
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/307	120/9376	0.254505971769815	CALM1	-1.51216173436847
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/307	181/9376	0.337466481904728	HLA-DRB5/CALM1	-1.65594687569242
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	3/307	235/9376	0.389881488668653	RPS6/COX8C/COX4I1	-1.74271513756927
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/307	136/9376	0.224564092738072	CCNE1	-1.67592469769076
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	3/307	250/9376	0.366488599348534	CTSV/AP1M2/LAPTM4B	-1.86792455819613
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	3/307	254/9376	0.360717125343046	CALM1/SLC25A4/ERBB2	-1.90037811286992
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/307	143/9376	0.213571444841803	HLA-DRB5	-1.7435363262525
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/307	144/9376	0.21208830980818	SLC25A4	-1.75301655413961
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/307	149/9376	0.204971252432066	FCER1A	-1.79978584379373
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	4/307	370/9376	0.330169909323004	CGA/LEP/TMEM97/GHR	-2.41865914697176
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/307	243/9376	0.12568196136781	HNRNPA1	-2.54062736567028
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/307	449/9376	0.0680194133905965	CALM1	-3.72350888156447