ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 73/496 175/18639 0.417142857142857 15.6756566820277 1.1930182969156e-68 8.30340734653259e-66 GO:0019843 rRNA binding 17/496 65/18639 0.261538461538462 9.82825682382134 7.37546134054635e-13 2.56666054651013e-10 GO:0031720 haptoglobin binding 7/496 10/18639 0.7 26.3050403225806 1.01474461445368e-09 2.35420750553253e-07 GO:0045296 cadherin binding 31/496 334/18639 0.092814371257485 3.48783682634731 1.70914814407991e-09 2.97391777069904e-07 GO:0004601 peroxidase activity 13/496 57/18639 0.228070175438596 8.57056451612903 2.41349255799912e-09 3.16277129939953e-07 GO:1990948 ubiquitin ligase inhibitor activity 7/496 11/18639 0.636363636363636 23.9136730205279 2.72652698224097e-09 3.16277129939953e-07 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 13/496 59/18639 0.220338983050847 8.28003690541279 3.80072338465757e-09 3.77900496531667e-07 GO:0048027 mRNA 5'-UTR binding 9/496 24/18639 0.375 14.0919858870968 5.70473437436799e-09 4.96311890570015e-07 GO:0005344 oxygen carrier activity 7/496 14/18639 0.5 18.789314516129 2.64499276658791e-08 2.04546107282798e-06 GO:0055105 ubiquitin-protein transferase inhibitor activity 7/496 15/18639 0.466666666666667 17.5366935483871 4.84573541969984e-08 3.37263185211109e-06 GO:0016209 antioxidant activity 14/496 86/18639 0.162790697674419 6.11745123780945 5.84475298806084e-08 3.69813461790032e-06 GO:0050786 RAGE receptor binding 6/496 11/18639 0.545454545454545 20.4974340175953 1.42134781701519e-07 8.2438173386881e-06 GO:0098631 cell adhesion mediator activity 12/496 76/18639 0.157894736842105 5.93346774193548 7.29782018437587e-07 3.90714065255816e-05 GO:0098632 cell-cell adhesion mediator activity 10/496 55/18639 0.181818181818182 6.8324780058651 1.62449875441185e-06 8.07607952193321e-05 GO:0055106 ubiquitin-protein transferase regulator activity 8/496 36/18639 0.222222222222222 8.3508064516129 3.73170402764535e-06 0.000173151066882744 GO:0004857 enzyme inhibitor activity 28/496 416/18639 0.0673076923076923 2.52933080024814 7.36368957843364e-06 0.000320320496661863 GO:0048306 calcium-dependent protein binding 11/496 80/18639 0.1375 5.16706149193548 8.47637412088618e-06 0.000347032728713928 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 5/496 13/18639 0.384615384615385 14.4533188585608 1.4104199362577e-05 0.000545362375352979 GO:0008017 microtubule binding 21/496 276/18639 0.0760869565217391 2.85924351332398 1.69944378751794e-05 0.000622533092690783 GO:0019825 oxygen binding 7/496 34/18639 0.205882352941176 7.7367765654649 2.61204003167416e-05 0.000908989931022609 GO:0005201 extracellular matrix structural constituent 15/496 168/18639 0.0892857142857143 3.35523473502304 4.44858996441895e-05 0.00147438981677885 GO:0019207 kinase regulator activity 19/496 287/18639 0.0662020905923345 2.48778380352928 0.000264138690756498 0.0081998712332299 GO:0015631 tubulin binding 23/496 385/18639 0.0597402597402597 2.24495705906996 0.000280510891405854 0.0081998712332299 GO:0019838 growth factor binding 12/496 136/18639 0.0882352941176471 3.31576138519924 0.000282754180456203 0.0081998712332299 GO:0004602 glutathione peroxidase activity 5/496 23/18639 0.217391304347826 8.16926718092567 0.000295845796982843 0.00823634698800234 GO:0019887 protein kinase regulator activity 17/496 255/18639 0.0666666666666667 2.50524193548387 0.000505787208617126 0.0135395345075969 GO:0003779 actin binding 24/496 443/18639 0.054176072234763 2.03586252093497 0.000844747427794448 0.0217757114720347 GO:0001968 fibronectin binding 5/496 30/18639 0.166666666666667 6.26310483870968 0.00107479853894528 0.0267164208252114 GO:0098641 cadherin binding involved in cell-cell adhesion 4/496 18/18639 0.222222222222222 8.3508064516129 0.00112662109234272 0.0270389062162253 GO:0008301 DNA binding, bending 4/496 19/18639 0.210526315789474 7.91129032258065 0.00139728443306527 0.0324169988471144 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 6/496 48/18639 0.125 4.69732862903226 0.00163893712543834 0.0367967819130673 GO:0004860 protein kinase inhibitor activity 8/496 84/18639 0.0952380952380952 3.57891705069124 0.00176472876722214 0.0383828506870816 GO:0019210 kinase inhibitor activity 8/496 90/18639 0.0888888888888889 3.34032258064516 0.00273346833377914 0.0576513321306145 GO:0045295 gamma-catenin binding 3/496 12/18639 0.25 9.39465725806452 0.00344450679922797 0.0684964780646477 GO:0097371 MDM2/MDM4 family protein binding 3/496 12/18639 0.25 9.39465725806452 0.00344450679922797 0.0684964780646477 GO:0031994 insulin-like growth factor I binding 3/496 13/18639 0.230769230769231 8.67199131513648 0.00439008036177343 0.0848748869942863 GO:0020037 heme binding 10/496 142/18639 0.0704225352112676 2.64638232621536 0.00473828441679774 0.0891309717321954 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/496 44/18639 0.113636363636364 4.27029875366569 0.00604089394985319 0.110643741818364 GO:0046906 tetrapyrrole binding 10/496 152/18639 0.0657894736842105 2.47227822580645 0.00757655342522767 0.135212338050217 GO:0003777 microtubule motor activity 6/496 68/18639 0.0882352941176471 3.31576138519924 0.00937455589778026 0.163117272621376 GO:0051015 actin filament binding 12/496 209/18639 0.0574162679425837 2.15762463343109 0.0103824377005855 0.176248210722135 GO:0019956 chemokine binding 4/496 33/18639 0.121212121212121 4.5549853372434 0.0110047869182734 0.182365040359959 GO:0000400 four-way junction DNA binding 3/496 18/18639 0.166666666666667 6.26310483870968 0.0113497895864496 0.183708222143464 GO:0019208 phosphatase regulator activity 8/496 117/18639 0.0683760683760684 2.56947890818859 0.0129774744694711 0.204405677215235 GO:0005520 insulin-like growth factor binding 3/496 19/18639 0.157894736842105 5.93346774193548 0.0132158843027092 0.204405677215235 GO:0070182 DNA polymerase binding 3/496 21/18639 0.142857142857143 5.36837557603687 0.0174425785472056 0.258298609975641 GO:0072542 protein phosphatase activator activity 3/496 21/18639 0.142857142857143 5.36837557603687 0.0174425785472056 0.258298609975641 GO:0000217 DNA secondary structure binding 4/496 39/18639 0.102564102564103 3.85421836228288 0.0195340938243411 0.283244360452946 GO:0001618 virus receptor activity 6/496 81/18639 0.0740740740740741 2.78360215053763 0.0208840667529276 0.290402768001047 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 4/496 40/18639 0.1 3.75786290322581 0.0212610426003226 0.290402768001047 GO:0140272 exogenous protein binding 6/496 82/18639 0.0731707317073171 2.74965578284815 0.0220447895024667 0.290402768001047 GO:0016493 C-C chemokine receptor activity 3/496 23/18639 0.130434782608696 4.9015603085554 0.0223364369976292 0.290402768001047 GO:0017134 fibroblast growth factor binding 3/496 23/18639 0.130434782608696 4.9015603085554 0.0223364369976292 0.290402768001047 GO:0140375 immune receptor activity 9/496 156/18639 0.0576923076923077 2.16799782878412 0.023920841995108 0.290402768001047 GO:0019888 protein phosphatase regulator activity 7/496 107/18639 0.0654205607476635 2.45841498341875 0.0242142260255676 0.290402768001047 GO:0008307 structural constituent of muscle 4/496 42/18639 0.0952380952380952 3.57891705069124 0.0249878260290015 0.290402768001047 GO:0042056 chemoattractant activity 4/496 42/18639 0.0952380952380952 3.57891705069124 0.0249878260290015 0.290402768001047 GO:0005540 hyaluronic acid binding 3/496 24/18639 0.125 4.69732862903226 0.0250347213794006 0.290402768001047 GO:0019957 C-C chemokine binding 3/496 24/18639 0.125 4.69732862903226 0.0250347213794006 0.290402768001047 GO:0050699 WW domain binding 3/496 24/18639 0.125 4.69732862903226 0.0250347213794006 0.290402768001047 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/496 10/18639 0.2 7.51572580645161 0.0276070579757583 0.296711476461548 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/496 10/18639 0.2 7.51572580645161 0.0276070579757583 0.296711476461548 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 2/496 10/18639 0.2 7.51572580645161 0.0276070579757583 0.296711476461548 GO:0019911 structural constituent of myelin sheath 2/496 10/18639 0.2 7.51572580645161 0.0276070579757583 0.296711476461548 GO:0019211 phosphatase activator activity 3/496 25/18639 0.12 4.50943548387097 0.0279003464364052 0.296711476461548 GO:0031406 carboxylic acid binding 10/496 187/18639 0.053475935828877 2.00955235466621 0.0283729402971767 0.296711476461548 GO:0004866 endopeptidase inhibitor activity 9/496 161/18639 0.0559006211180124 2.1006687036666 0.0285627427053502 0.296711476461548 GO:0038024 cargo receptor activity 5/496 65/18639 0.0769230769230769 2.89066377171216 0.0292756065637808 0.299422354651219 GO:0043177 organic acid binding 10/496 189/18639 0.0529100529100529 1.98828725038402 0.0302195900780307 0.299422354651219 GO:0001637 G protein-coupled chemoattractant receptor activity 3/496 26/18639 0.115384615384615 4.33599565756824 0.0309326591684056 0.299422354651219 GO:0004950 chemokine receptor activity 3/496 26/18639 0.115384615384615 4.33599565756824 0.0309326591684056 0.299422354651219 GO:0008432 JUN kinase binding 2/496 11/18639 0.181818181818182 6.8324780058651 0.03315638053326 0.299422354651219 GO:0010854 adenylate cyclase regulator activity 2/496 11/18639 0.181818181818182 6.8324780058651 0.03315638053326 0.299422354651219 GO:0034056 estrogen response element binding 2/496 11/18639 0.181818181818182 6.8324780058651 0.03315638053326 0.299422354651219 GO:0045294 alpha-catenin binding 2/496 11/18639 0.181818181818182 6.8324780058651 0.03315638053326 0.299422354651219 GO:0048407 platelet-derived growth factor binding 2/496 11/18639 0.181818181818182 6.8324780058651 0.03315638053326 0.299422354651219 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 4/496 46/18639 0.0869565217391304 3.26770687237027 0.0335559535384986 0.299422354651219 GO:0030291 protein serine/threonine kinase inhibitor activity 4/496 46/18639 0.0869565217391304 3.26770687237027 0.0335559535384986 0.299422354651219 GO:0005504 fatty acid binding 4/496 47/18639 0.0851063829787234 3.19818119423473 0.0359335468656708 0.316579096436796 GO:0030414 peptidase inhibitor activity 9/496 169/18639 0.0532544378698225 2.00122876503149 0.0372472599508961 0.322162113505675 GO:0097718 disordered domain specific binding 3/496 28/18639 0.107142857142857 4.02628168202765 0.0374930045890226 0.322162113505675 GO:0008603 cAMP-dependent protein kinase regulator activity 2/496 12/18639 0.166666666666667 6.26310483870968 0.0390987552800664 0.323961115177693 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/496 12/18639 0.166666666666667 6.26310483870968 0.0390987552800664 0.323961115177693 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/496 12/18639 0.166666666666667 6.26310483870968 0.0390987552800664 0.323961115177693 GO:0003785 actin monomer binding 3/496 29/18639 0.103448275862069 3.88744438264739 0.0410180772866066 0.329727631670199 GO:0051861 glycolipid binding 3/496 29/18639 0.103448275862069 3.88744438264739 0.0410180772866066 0.329727631670199 GO:0004867 serine-type endopeptidase inhibitor activity 6/496 95/18639 0.0631578947368421 2.37338709677419 0.0412159539587748 0.329727631670199 GO:0016769 transferase activity, transferring nitrogenous groups 3/496 30/18639 0.1 3.75786290322581 0.0447039660357891 0.343532159990566 GO:0005542 folic acid binding 2/496 13/18639 0.153846153846154 5.78132754342432 0.0454094234470288 0.343532159990566 GO:0032396 inhibitory MHC class I receptor activity 2/496 13/18639 0.153846153846154 5.78132754342432 0.0454094234470288 0.343532159990566 GO:0035325 Toll-like receptor binding 2/496 13/18639 0.153846153846154 5.78132754342432 0.0454094234470288 0.343532159990566 GO:0071837 HMG box domain binding 2/496 13/18639 0.153846153846154 5.78132754342432 0.0454094234470288 0.343532159990566 GO:0047499 calcium-independent phospholipase A2 activity 3/496 31/18639 0.0967741935483871 3.63664151925078 0.0485485090322764 0.36333077727381 GO:0005080 protein kinase C binding 4/496 52/18639 0.0769230769230769 2.89066377171216 0.0492461225582259 0.364630864899205 GO:0008559 ABC-type xenobiotic transporter activity 2/496 14/18639 0.142857142857143 5.36837557603687 0.0520646610076238 0.373207351860001 GO:0003774 cytoskeletal motor activity 8/496 153/18639 0.0522875816993464 1.96489563567362 0.0522891476921771 0.373207351860001 GO:0042910 xenobiotic transmembrane transporter activity 3/496 32/18639 0.09375 3.52299647177419 0.0525493110377587 0.373207351860001 GO:0047498 calcium-dependent phospholipase A2 activity 3/496 32/18639 0.09375 3.52299647177419 0.0525493110377587 0.373207351860001 GO:0005506 iron ion binding 8/496 154/18639 0.051948051948052 1.95213657310431 0.0539365455469901 0.379190259603082 GO:0051287 NAD binding 4/496 54/18639 0.0740740740740741 2.78360215053763 0.0552340185772822 0.384428769297884 GO:0140416 transcription regulator inhibitor activity 3/496 33/18639 0.0909090909090909 3.41623900293255 0.0567037634497072 0.390051808774345 GO:0061135 endopeptidase regulator activity 9/496 184/18639 0.0489130434782609 1.83808511570827 0.0580562312762104 0.390051808774345 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/496 15/18639 0.133333333333333 5.01048387096774 0.0590417413213298 0.390051808774345 GO:0031386 protein tag activity 2/496 15/18639 0.133333333333333 5.01048387096774 0.0590417413213298 0.390051808774345 GO:0141047 molecular tag activity 2/496 15/18639 0.133333333333333 5.01048387096774 0.0590417413213298 0.390051808774345 GO:0033293 monocarboxylic acid binding 5/496 79/18639 0.0632911392405063 2.37839424254798 0.0594044421409203 0.390051808774345 GO:0019212 phosphatase inhibitor activity 4/496 56/18639 0.0714285714285714 2.68418778801843 0.0615963938887237 0.396954538393997 GO:0030170 pyridoxal phosphate binding 4/496 56/18639 0.0714285714285714 2.68418778801843 0.0615963938887237 0.396954538393997 GO:0070279 vitamin B6 binding 4/496 57/18639 0.0701754385964912 2.63709677419355 0.0649165238684221 0.412124586805083 GO:0004623 phospholipase A2 activity 3/496 35/18639 0.0857142857142857 3.22102534562212 0.0654622313049356 0.412124586805083 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/496 16/18639 0.125 4.69732862903226 0.0663188990261053 0.412124586805083 GO:0008142 oxysterol binding 2/496 16/18639 0.125 4.69732862903226 0.0663188990261053 0.412124586805083 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/496 17/18639 0.117647058823529 4.42101518026565 0.0738752951401506 0.447106134065607 GO:0036041 long-chain fatty acid binding 2/496 17/18639 0.117647058823529 4.42101518026565 0.0738752951401506 0.447106134065607 GO:0070492 oligosaccharide binding 2/496 17/18639 0.117647058823529 4.42101518026565 0.0738752951401506 0.447106134065607 GO:0061134 peptidase regulator activity 10/496 226/18639 0.0442477876106195 1.66277119611761 0.0808475070577649 0.473807703339307 GO:0003746 translation elongation factor activity 2/496 18/18639 0.111111111111111 4.17540322580645 0.0816909833343632 0.473807703339307 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 2/496 18/18639 0.111111111111111 4.17540322580645 0.0816909833343632 0.473807703339307 GO:0032393 MHC class I receptor activity 2/496 18/18639 0.111111111111111 4.17540322580645 0.0816909833343632 0.473807703339307 GO:0070064 proline-rich region binding 2/496 18/18639 0.111111111111111 4.17540322580645 0.0816909833343632 0.473807703339307 GO:0005507 copper ion binding 4/496 63/18639 0.0634920634920635 2.38594470046083 0.08673043932477 0.498879221239999 GO:0008574 plus-end-directed microtubule motor activity 2/496 19/18639 0.105263157894737 3.95564516129032 0.0897468773380873 0.506925440935749 GO:0015245 fatty acid transmembrane transporter activity 2/496 19/18639 0.105263157894737 3.95564516129032 0.0897468773380873 0.506925440935749 GO:0019955 cytokine binding 7/496 144/18639 0.0486111111111111 1.82673891129032 0.0903143026954496 0.506925440935749 GO:0017080 sodium channel regulator activity 3/496 41/18639 0.0731707317073171 2.74965578284815 0.0951015077713833 0.529525195271062 GO:0010851 cyclase regulator activity 2/496 20/18639 0.1 3.75786290322581 0.0980247194419139 0.537206336469071 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/496 20/18639 0.1 3.75786290322581 0.0980247194419139 0.537206336469071 GO:0001664 G protein-coupled receptor binding 12/496 297/18639 0.0404040404040404 1.5183284457478 0.100439018891063 0.543332532764504 GO:0019209 kinase activator activity 7/496 148/18639 0.0472972972972973 1.77736758936356 0.100703874607214 0.543332532764504 GO:0019842 vitamin binding 7/496 150/18639 0.0466666666666667 1.75366935483871 0.106133520869288 0.568222542500187 GO:0001223 transcription coactivator binding 3/496 44/18639 0.0681818181818182 2.56217925219941 0.111636314063613 0.58513369431369 GO:0004896 cytokine receptor activity 5/496 96/18639 0.0520833333333333 1.95722026209677 0.113011124229454 0.58513369431369 GO:0005539 glycosaminoglycan binding 10/496 242/18639 0.0413223140495868 1.55283591042389 0.11319969296835 0.58513369431369 GO:0008093 cytoskeletal anchor activity 2/496 22/18639 0.0909090909090909 3.41623900293255 0.115177178334735 0.58513369431369 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/496 22/18639 0.0909090909090909 3.41623900293255 0.115177178334735 0.58513369431369 GO:0033691 sialic acid binding 2/496 22/18639 0.0909090909090909 3.41623900293255 0.115177178334735 0.58513369431369 GO:0140517 protein-RNA adaptor activity 2/496 22/18639 0.0909090909090909 3.41623900293255 0.115177178334735 0.58513369431369 GO:0008009 chemokine activity 3/496 45/18639 0.0666666666666667 2.50524193548387 0.117376550040871 0.591986078467 GO:0042379 chemokine receptor binding 4/496 72/18639 0.0555555555555556 2.08770161290323 0.125124150912607 0.626520928310606 GO:0043495 protein-membrane adaptor activity 3/496 47/18639 0.0638297872340425 2.39863589567605 0.12917615443645 0.636071292312701 GO:0140359 ABC-type transporter activity 3/496 47/18639 0.0638297872340425 2.39863589567605 0.12917615443645 0.636071292312701 GO:0043539 protein serine/threonine kinase activator activity 4/496 73/18639 0.0547945205479452 2.05910296067167 0.12977316596035 0.636071292312701 GO:0005178 integrin binding 7/496 161/18639 0.0434782608695652 1.63385343618513 0.13869903086545 0.67506661176471 GO:0008483 transaminase activity 2/496 25/18639 0.08 3.00629032258065 0.142158381240973 0.687098842664703 GO:0003713 transcription coactivator activity 10/496 256/18639 0.0390625 1.46791519657258 0.146688642803161 0.703689878402269 GO:0005006 epidermal growth factor receptor activity 3/496 50/18639 0.06 2.25471774193548 0.147613106676338 0.703689878402269 GO:0070006 metalloaminopeptidase activity 2/496 26/18639 0.0769230769230769 2.89066377171216 0.151427191413687 0.71696139608113 GO:0044389 ubiquitin-like protein ligase binding 12/496 322/18639 0.0372670807453416 1.4004458024444 0.152520397844991 0.71725808716293 GO:0002020 protease binding 6/496 136/18639 0.0441176470588235 1.65788069259962 0.155195905429755 0.724941947510802 GO:0004364 glutathione transferase activity 2/496 27/18639 0.0740740740740741 2.78360215053763 0.160810914315969 0.746162642426096 GO:0030295 protein kinase activator activity 6/496 139/18639 0.0431654676258993 1.62209909491761 0.166514465287751 0.754023214228191 GO:0004864 protein phosphatase inhibitor activity 3/496 53/18639 0.0566037735849057 2.1270922093731 0.166838469814858 0.754023214228191 GO:0016860 intramolecular oxidoreductase activity 3/496 53/18639 0.0566037735849057 2.1270922093731 0.166838469814858 0.754023214228191 GO:0017046 peptide hormone binding 3/496 53/18639 0.0566037735849057 2.1270922093731 0.166838469814858 0.754023214228191 GO:0046625 sphingolipid binding 2/496 28/18639 0.0714285714285714 2.68418778801843 0.170296907371888 0.760081924774085 GO:0004713 protein tyrosine kinase activity 6/496 140/18639 0.0428571428571429 1.61051267281106 0.170363190035571 0.760081924774085 GO:0005125 cytokine activity 9/496 234/18639 0.0384615384615385 1.44533188585608 0.173125281090338 0.763853117241533 GO:0015485 cholesterol binding 3/496 54/18639 0.0555555555555556 2.08770161290323 0.173403437534716 0.763853117241533 GO:0008201 heparin binding 7/496 172/18639 0.0406976744186047 1.52936280945236 0.17551892123108 0.76830924010586 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/496 29/18639 0.0689655172413793 2.59162958843159 0.179873117007835 0.769121026192099 GO:0043236 laminin binding 2/496 29/18639 0.0689655172413793 2.59162958843159 0.179873117007835 0.769121026192099 GO:0097472 cyclin-dependent protein kinase activity 2/496 29/18639 0.0689655172413793 2.59162958843159 0.179873117007835 0.769121026192099 GO:0051117 ATPase binding 4/496 84/18639 0.0476190476190476 1.78945852534562 0.185195670485179 0.769121026192099 GO:0170055 lipid transmembrane transporter activity 3/496 56/18639 0.0535714285714286 2.01314084101382 0.18674441703829 0.769121026192099 GO:0035401 histone H3Y41 kinase activity 5/496 115/18639 0.0434782608695652 1.63385343618513 0.192247498377128 0.769121026192099 GO:0140801 histone H2AXY142 kinase activity 5/496 115/18639 0.0434782608695652 1.63385343618513 0.192247498377128 0.769121026192099 GO:0016853 isomerase activity 7/496 180/18639 0.0388888888888889 1.46139112903226 0.204650641430744 0.769121026192099 GO:0004879 nuclear receptor activity 3/496 59/18639 0.0508474576271186 1.91077774740295 0.20722532971676 0.769121026192099 GO:0033218 amide binding 9/496 247/18639 0.0364372469635627 1.3692617866005 0.213630033847643 0.769121026192099 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/496 60/18639 0.05 1.8789314516129 0.214162269352779 0.769121026192099 GO:0098531 ligand-modulated transcription factor activity 3/496 60/18639 0.05 1.8789314516129 0.214162269352779 0.769121026192099 GO:0140311 protein sequestering activity 2/496 33/18639 0.0606060606060606 2.2774926686217 0.218858437979 0.769121026192099 GO:0003697 single-stranded DNA binding 5/496 121/18639 0.0413223140495868 1.55283591042389 0.220560292404404 0.769121026192099 GO:0051082 unfolded protein binding 5/496 121/18639 0.0413223140495868 1.55283591042389 0.220560292404404 0.769121026192099 GO:0015026 coreceptor activity 3/496 61/18639 0.0491803278688525 1.84812929666843 0.221147992402553 0.769121026192099 GO:0072341 modified amino acid binding 4/496 91/18639 0.043956043956044 1.65180786954981 0.223821772880721 0.769121026192099 GO:0030332 cyclin binding 2/496 34/18639 0.0588235294117647 2.21050759013283 0.228724023895755 0.769121026192099 GO:0090482 vitamin transmembrane transporter activity 2/496 34/18639 0.0588235294117647 2.21050759013283 0.228724023895755 0.769121026192099 GO:0005345 purine nucleobase transmembrane transporter activity 1/496 10/18639 0.1 3.75786290322581 0.236452168932727 0.769121026192099 GO:0005522 profilin binding 1/496 10/18639 0.1 3.75786290322581 0.236452168932727 0.769121026192099 GO:0015187 glycine transmembrane transporter activity 1/496 10/18639 0.1 3.75786290322581 0.236452168932727 0.769121026192099 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/496 10/18639 0.1 3.75786290322581 0.236452168932727 0.769121026192099 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/496 10/18639 0.1 3.75786290322581 0.236452168932727 0.769121026192099 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/496 10/18639 0.1 3.75786290322581 0.236452168932727 0.769121026192099 GO:0030957 Tat protein binding 1/496 10/18639 0.1 3.75786290322581 0.236452168932727 0.769121026192099 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/496 10/18639 0.1 3.75786290322581 0.236452168932727 0.769121026192099 GO:0032356 oxidized DNA binding 1/496 10/18639 0.1 3.75786290322581 0.236452168932727 0.769121026192099 GO:0035374 chondroitin sulfate binding 1/496 10/18639 0.1 3.75786290322581 0.236452168932727 0.769121026192099 GO:0043208 glycosphingolipid binding 1/496 10/18639 0.1 3.75786290322581 0.236452168932727 0.769121026192099 GO:0050815 phosphoserine residue binding 1/496 10/18639 0.1 3.75786290322581 0.236452168932727 0.769121026192099 GO:0071723 lipopeptide binding 1/496 10/18639 0.1 3.75786290322581 0.236452168932727 0.769121026192099 GO:0098505 G-rich strand telomeric DNA binding 1/496 10/18639 0.1 3.75786290322581 0.236452168932727 0.769121026192099 GO:1990757 ubiquitin ligase activator activity 1/496 10/18639 0.1 3.75786290322581 0.236452168932727 0.769121026192099 GO:0005154 epidermal growth factor receptor binding 2/496 35/18639 0.0571428571428571 2.14735023041475 0.238618677992169 0.769121026192099 GO:0061631 ubiquitin conjugating enzyme activity 2/496 35/18639 0.0571428571428571 2.14735023041475 0.238618677992169 0.769121026192099 GO:0042562 hormone binding 4/496 94/18639 0.0425531914893617 1.59909059711736 0.240977743923791 0.769121026192099 GO:0003712 transcription coregulator activity 16/496 495/18639 0.0323232323232323 1.21466275659824 0.247286723054136 0.769121026192099 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/496 36/18639 0.0555555555555556 2.08770161290323 0.248533886769237 0.769121026192099 GO:0099106 ion channel regulator activity 6/496 160/18639 0.0375 1.40919858870968 0.254108815870662 0.769121026192099 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 5/496 128/18639 0.0390625 1.46791519657258 0.255053916272217 0.769121026192099 GO:0002162 dystroglycan binding 1/496 11/18639 0.0909090909090909 3.41623900293255 0.256781747772674 0.769121026192099 GO:0008199 ferric iron binding 1/496 11/18639 0.0909090909090909 3.41623900293255 0.256781747772674 0.769121026192099 GO:0015205 nucleobase transmembrane transporter activity 1/496 11/18639 0.0909090909090909 3.41623900293255 0.256781747772674 0.769121026192099 GO:0015217 ADP transmembrane transporter activity 1/496 11/18639 0.0909090909090909 3.41623900293255 0.256781747772674 0.769121026192099 GO:0016594 glycine binding 1/496 11/18639 0.0909090909090909 3.41623900293255 0.256781747772674 0.769121026192099 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/496 11/18639 0.0909090909090909 3.41623900293255 0.256781747772674 0.769121026192099 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/496 11/18639 0.0909090909090909 3.41623900293255 0.256781747772674 0.769121026192099 GO:0019206 nucleoside kinase activity 1/496 11/18639 0.0909090909090909 3.41623900293255 0.256781747772674 0.769121026192099 GO:0019215 intermediate filament binding 1/496 11/18639 0.0909090909090909 3.41623900293255 0.256781747772674 0.769121026192099 GO:0032050 clathrin heavy chain binding 1/496 11/18639 0.0909090909090909 3.41623900293255 0.256781747772674 0.769121026192099 GO:0032794 GTPase activating protein binding 1/496 11/18639 0.0909090909090909 3.41623900293255 0.256781747772674 0.769121026192099 GO:0034713 type I transforming growth factor beta receptor binding 1/496 11/18639 0.0909090909090909 3.41623900293255 0.256781747772674 0.769121026192099 GO:0043522 leucine zipper domain binding 1/496 11/18639 0.0909090909090909 3.41623900293255 0.256781747772674 0.769121026192099 GO:0047676 arachidonate-CoA ligase activity 1/496 11/18639 0.0909090909090909 3.41623900293255 0.256781747772674 0.769121026192099 GO:0048185 activin binding 1/496 11/18639 0.0909090909090909 3.41623900293255 0.256781747772674 0.769121026192099 GO:0050998 nitric-oxide synthase binding 1/496 11/18639 0.0909090909090909 3.41623900293255 0.256781747772674 0.769121026192099 GO:0022829 wide pore channel activity 2/496 37/18639 0.0540540540540541 2.03127724498692 0.258461567507031 0.769121026192099 GO:0042805 actinin binding 2/496 37/18639 0.0540540540540541 2.03127724498692 0.258461567507031 0.769121026192099 GO:0016500 protein-hormone receptor activity 3/496 67/18639 0.0447761194029851 1.68262518054887 0.263886903905007 0.769121026192099 GO:0050840 extracellular matrix binding 3/496 67/18639 0.0447761194029851 1.68262518054887 0.263886903905007 0.769121026192099 GO:0005109 frizzled binding 2/496 38/18639 0.0526315789473684 1.97782258064516 0.268394051444838 0.769121026192099 GO:0005501 retinoid binding 2/496 38/18639 0.0526315789473684 1.97782258064516 0.268394051444838 0.769121026192099 GO:0019840 isoprenoid binding 2/496 38/18639 0.0526315789473684 1.97782258064516 0.268394051444838 0.769121026192099 GO:0032934 sterol binding 3/496 68/18639 0.0441176470588235 1.65788069259962 0.271115439709689 0.769121026192099 GO:0005179 hormone activity 5/496 132/18639 0.0378787878787879 1.42343291788856 0.275327677580602 0.769121026192099 GO:0004032 aldose reductase (NADPH) activity 1/496 12/18639 0.0833333333333333 3.13155241935484 0.276571110726547 0.769121026192099 GO:0004126 cytidine deaminase activity 1/496 12/18639 0.0833333333333333 3.13155241935484 0.276571110726547 0.769121026192099 GO:0004859 phospholipase inhibitor activity 1/496 12/18639 0.0833333333333333 3.13155241935484 0.276571110726547 0.769121026192099 GO:0004875 complement receptor activity 1/496 12/18639 0.0833333333333333 3.13155241935484 0.276571110726547 0.769121026192099 GO:0008504 monoamine transmembrane transporter activity 1/496 12/18639 0.0833333333333333 3.13155241935484 0.276571110726547 0.769121026192099 GO:0010853 cyclase activator activity 1/496 12/18639 0.0833333333333333 3.13155241935484 0.276571110726547 0.769121026192099 GO:0015132 prostaglandin transmembrane transporter activity 1/496 12/18639 0.0833333333333333 3.13155241935484 0.276571110726547 0.769121026192099 GO:0043047 single-stranded telomeric DNA binding 1/496 12/18639 0.0833333333333333 3.13155241935484 0.276571110726547 0.769121026192099 GO:0031625 ubiquitin protein ligase binding 10/496 302/18639 0.033112582781457 1.24432546464431 0.28524951206419 0.769121026192099 GO:0051087 protein-folding chaperone binding 5/496 134/18639 0.0373134328358209 1.40218765045739 0.285588215586767 0.769121026192099 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/496 70/18639 0.0428571428571429 1.61051267281106 0.285633383605442 0.769121026192099 GO:0097110 scaffold protein binding 3/496 70/18639 0.0428571428571429 1.61051267281106 0.285633383605442 0.769121026192099 GO:0004177 aminopeptidase activity 2/496 40/18639 0.05 1.8789314516129 0.28824472684586 0.769121026192099 GO:0016247 channel regulator activity 6/496 168/18639 0.0357142857142857 1.34209389400922 0.290389607381955 0.769121026192099 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/496 13/18639 0.0769230769230769 2.89066377171216 0.295834584666507 0.769121026192099 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/496 13/18639 0.0769230769230769 2.89066377171216 0.295834584666507 0.769121026192099 GO:0005172 vascular endothelial growth factor receptor binding 1/496 13/18639 0.0769230769230769 2.89066377171216 0.295834584666507 0.769121026192099 GO:0019855 calcium channel inhibitor activity 1/496 13/18639 0.0769230769230769 2.89066377171216 0.295834584666507 0.769121026192099 GO:0031432 titin binding 1/496 13/18639 0.0769230769230769 2.89066377171216 0.295834584666507 0.769121026192099 GO:0045159 myosin II binding 1/496 13/18639 0.0769230769230769 2.89066377171216 0.295834584666507 0.769121026192099 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/496 13/18639 0.0769230769230769 2.89066377171216 0.295834584666507 0.769121026192099 GO:0061459 L-arginine transmembrane transporter activity 1/496 13/18639 0.0769230769230769 2.89066377171216 0.295834584666507 0.769121026192099 GO:0071714 icosanoid transmembrane transporter activity 1/496 13/18639 0.0769230769230769 2.89066377171216 0.295834584666507 0.769121026192099 GO:0097157 pre-mRNA intronic binding 1/496 13/18639 0.0769230769230769 2.89066377171216 0.295834584666507 0.769121026192099 GO:0044325 transmembrane transporter binding 5/496 136/18639 0.0367647058823529 1.38156724383302 0.295919058258222 0.769121026192099 GO:0001530 lipopolysaccharide binding 2/496 41/18639 0.0487804878048781 1.8331038552321 0.298149507311217 0.769121026192099 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 2/496 41/18639 0.0487804878048781 1.8331038552321 0.298149507311217 0.769121026192099 GO:0042169 SH2 domain binding 2/496 41/18639 0.0487804878048781 1.8331038552321 0.298149507311217 0.769121026192099 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/496 41/18639 0.0487804878048781 1.8331038552321 0.298149507311217 0.769121026192099 GO:0141108 transporter regulator activity 6/496 170/18639 0.0352941176470588 1.3263045540797 0.299629014985159 0.769121026192099 GO:0005518 collagen binding 3/496 72/18639 0.0416666666666667 1.56577620967742 0.300211904242113 0.769121026192099 GO:0019894 kinesin binding 2/496 42/18639 0.0476190476190476 1.78945852534562 0.308032239281508 0.769121026192099 GO:0035198 miRNA binding 2/496 42/18639 0.0476190476190476 1.78945852534562 0.308032239281508 0.769121026192099 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 15/496 484/18639 0.0309917355371901 1.16462693281792 0.309541577287033 0.769121026192099 GO:0005126 cytokine receptor binding 9/496 275/18639 0.0327272727272727 1.22984604105572 0.311220225995355 0.769121026192099 GO:1901681 sulfur compound binding 9/496 275/18639 0.0327272727272727 1.22984604105572 0.311220225995355 0.769121026192099 GO:0005347 ATP transmembrane transporter activity 1/496 14/18639 0.0714285714285714 2.68418778801843 0.314586117255652 0.769121026192099 GO:0008392 arachidonate epoxygenase activity 1/496 14/18639 0.0714285714285714 2.68418778801843 0.314586117255652 0.769121026192099 GO:0019763 immunoglobulin receptor activity 1/496 14/18639 0.0714285714285714 2.68418778801843 0.314586117255652 0.769121026192099 GO:0032036 myosin heavy chain binding 1/496 14/18639 0.0714285714285714 2.68418778801843 0.314586117255652 0.769121026192099 GO:0034236 protein kinase A catalytic subunit binding 1/496 14/18639 0.0714285714285714 2.68418778801843 0.314586117255652 0.769121026192099 GO:0044548 S100 protein binding 1/496 14/18639 0.0714285714285714 2.68418778801843 0.314586117255652 0.769121026192099 GO:0070742 C2H2 zinc finger domain binding 1/496 14/18639 0.0714285714285714 2.68418778801843 0.314586117255652 0.769121026192099 GO:0098847 sequence-specific single stranded DNA binding 1/496 14/18639 0.0714285714285714 2.68418778801843 0.314586117255652 0.769121026192099 GO:1990825 sequence-specific mRNA binding 1/496 14/18639 0.0714285714285714 2.68418778801843 0.314586117255652 0.769121026192099 GO:0003684 damaged DNA binding 3/496 74/18639 0.0405405405405405 1.52345793374019 0.314827272704071 0.769121026192099 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/496 43/18639 0.0465116279069767 1.7478432108027 0.317887091385955 0.769121026192099 GO:0008200 ion channel inhibitor activity 2/496 43/18639 0.0465116279069767 1.7478432108027 0.317887091385955 0.769121026192099 GO:0005496 steroid binding 4/496 108/18639 0.037037037037037 1.39180107526882 0.324060813651856 0.769121026192099 GO:0016248 channel inhibitor activity 2/496 44/18639 0.0454545454545455 1.70811950146628 0.327708556972733 0.769121026192099 GO:0030547 signaling receptor inhibitor activity 2/496 44/18639 0.0454545454545455 1.70811950146628 0.327708556972733 0.769121026192099 GO:0001216 DNA-binding transcription activator activity 15/496 491/18639 0.0305498981670061 1.14802329019118 0.328963674849934 0.769121026192099 GO:0017022 myosin binding 3/496 76/18639 0.0394736842105263 1.48336693548387 0.32945688907469 0.769121026192099 GO:0030246 carbohydrate binding 9/496 280/18639 0.0321428571428571 1.20788450460829 0.3296840580096 0.769121026192099 GO:0004620 phospholipase activity 4/496 109/18639 0.036697247706422 1.37903225806452 0.330106941581174 0.769121026192099 GO:0004129 cytochrome-c oxidase activity 1/496 15/18639 0.0666666666666667 2.50524193548387 0.332839286965246 0.769121026192099 GO:0004467 long-chain fatty acid-CoA ligase activity 1/496 15/18639 0.0666666666666667 2.50524193548387 0.332839286965246 0.769121026192099 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/496 15/18639 0.0666666666666667 2.50524193548387 0.332839286965246 0.769121026192099 GO:0005041 low-density lipoprotein particle receptor activity 1/496 15/18639 0.0666666666666667 2.50524193548387 0.332839286965246 0.769121026192099 GO:0005523 tropomyosin binding 1/496 15/18639 0.0666666666666667 2.50524193548387 0.332839286965246 0.769121026192099 GO:0016846 carbon-sulfur lyase activity 1/496 15/18639 0.0666666666666667 2.50524193548387 0.332839286965246 0.769121026192099 GO:0033130 acetylcholine receptor binding 1/496 15/18639 0.0666666666666667 2.50524193548387 0.332839286965246 0.769121026192099 GO:0050780 dopamine receptor binding 1/496 15/18639 0.0666666666666667 2.50524193548387 0.332839286965246 0.769121026192099 GO:0051371 muscle alpha-actinin binding 1/496 15/18639 0.0666666666666667 2.50524193548387 0.332839286965246 0.769121026192099 GO:0120283 protein serine/threonine kinase binding 1/496 15/18639 0.0666666666666667 2.50524193548387 0.332839286965246 0.769121026192099 GO:0004222 metalloendopeptidase activity 4/496 110/18639 0.0363636363636364 1.36649560117302 0.336159108927958 0.769121026192099 GO:0051540 metal cluster binding 3/496 77/18639 0.038961038961039 1.46410242982824 0.336770288893282 0.769121026192099 GO:0005319 lipid transporter activity 6/496 178/18639 0.0337078651685393 1.26669536063791 0.337073137737534 0.769121026192099 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/496 45/18639 0.0444444444444444 1.67016129032258 0.337491441016077 0.769121026192099 GO:0042605 peptide antigen binding 2/496 45/18639 0.0444444444444444 1.67016129032258 0.337491441016077 0.769121026192099 GO:0141110 transporter inhibitor activity 2/496 45/18639 0.0444444444444444 1.67016129032258 0.337491441016077 0.769121026192099 GO:0019199 transmembrane receptor protein kinase activity 3/496 78/18639 0.0384615384615385 1.44533188585608 0.344079291688818 0.769121026192099 GO:0140104 molecular carrier activity 8/496 249/18639 0.0321285140562249 1.20734551107656 0.34460121199088 0.769121026192099 GO:0005200 structural constituent of cytoskeleton 4/496 112/18639 0.0357142857142857 1.34209389400922 0.34827534208202 0.769121026192099 GO:0003688 DNA replication origin binding 1/496 16/18639 0.0625 2.34866431451613 0.350607312827855 0.769121026192099 GO:0004708 MAP kinase kinase activity 1/496 16/18639 0.0625 2.34866431451613 0.350607312827855 0.769121026192099 GO:0005159 insulin-like growth factor receptor binding 1/496 16/18639 0.0625 2.34866431451613 0.350607312827855 0.769121026192099 GO:0005521 lamin binding 1/496 16/18639 0.0625 2.34866431451613 0.350607312827855 0.769121026192099 GO:0008391 arachidonate monooxygenase activity 1/496 16/18639 0.0625 2.34866431451613 0.350607312827855 0.769121026192099 GO:0015378 sodium:chloride symporter activity 1/496 16/18639 0.0625 2.34866431451613 0.350607312827855 0.769121026192099 GO:0015562 efflux transmembrane transporter activity 1/496 16/18639 0.0625 2.34866431451613 0.350607312827855 0.769121026192099 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/496 16/18639 0.0625 2.34866431451613 0.350607312827855 0.769121026192099 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/496 16/18639 0.0625 2.34866431451613 0.350607312827855 0.769121026192099 GO:0016722 oxidoreductase activity, acting on metal ions 1/496 16/18639 0.0625 2.34866431451613 0.350607312827855 0.769121026192099 GO:0022858 alanine transmembrane transporter activity 1/496 16/18639 0.0625 2.34866431451613 0.350607312827855 0.769121026192099 GO:0030275 LRR domain binding 1/496 16/18639 0.0625 2.34866431451613 0.350607312827855 0.769121026192099 GO:0043023 ribosomal large subunit binding 1/496 16/18639 0.0625 2.34866431451613 0.350607312827855 0.769121026192099 GO:0055102 lipase inhibitor activity 1/496 16/18639 0.0625 2.34866431451613 0.350607312827855 0.769121026192099 GO:0097027 ubiquitin-protein transferase activator activity 1/496 16/18639 0.0625 2.34866431451613 0.350607312827855 0.769121026192099 GO:0140328 floppase activity 1/496 16/18639 0.0625 2.34866431451613 0.350607312827855 0.769121026192099 GO:0015101 organic cation transmembrane transporter activity 3/496 81/18639 0.037037037037037 1.39180107526882 0.36595522741378 0.769121026192099 GO:0008429 phosphatidylethanolamine binding 1/496 17/18639 0.0588235294117647 2.21050759013283 0.367903063933337 0.769121026192099 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/496 17/18639 0.0588235294117647 2.21050759013283 0.367903063933337 0.769121026192099 GO:0030169 low-density lipoprotein particle binding 1/496 17/18639 0.0588235294117647 2.21050759013283 0.367903063933337 0.769121026192099 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/496 17/18639 0.0588235294117647 2.21050759013283 0.367903063933337 0.769121026192099 GO:0030548 acetylcholine receptor regulator activity 1/496 17/18639 0.0588235294117647 2.21050759013283 0.367903063933337 0.769121026192099 GO:0031489 myosin V binding 1/496 17/18639 0.0588235294117647 2.21050759013283 0.367903063933337 0.769121026192099 GO:0070403 NAD+ binding 1/496 17/18639 0.0588235294117647 2.21050759013283 0.367903063933337 0.769121026192099 GO:1990226 histone methyltransferase binding 1/496 17/18639 0.0588235294117647 2.21050759013283 0.367903063933337 0.769121026192099 GO:0009055 electron transfer activity 4/496 116/18639 0.0344827586206897 1.2958147942158 0.372513288813772 0.769121026192099 GO:0005004 GPI-linked ephrin receptor activity 2/496 49/18639 0.0408163265306122 1.53382159315339 0.376143473427112 0.769121026192099 GO:0005008 hepatocyte growth factor receptor activity 2/496 49/18639 0.0408163265306122 1.53382159315339 0.376143473427112 0.769121026192099 GO:0005009 insulin receptor activity 2/496 49/18639 0.0408163265306122 1.53382159315339 0.376143473427112 0.769121026192099 GO:0005011 macrophage colony-stimulating factor receptor activity 2/496 49/18639 0.0408163265306122 1.53382159315339 0.376143473427112 0.769121026192099 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/496 49/18639 0.0408163265306122 1.53382159315339 0.376143473427112 0.769121026192099 GO:0005020 stem cell factor receptor activity 2/496 49/18639 0.0408163265306122 1.53382159315339 0.376143473427112 0.769121026192099 GO:0008288 boss receptor activity 2/496 49/18639 0.0408163265306122 1.53382159315339 0.376143473427112 0.769121026192099 GO:0036332 placental growth factor receptor activity 2/496 49/18639 0.0408163265306122 1.53382159315339 0.376143473427112 0.769121026192099 GO:0038062 protein tyrosine kinase collagen receptor activity 2/496 49/18639 0.0408163265306122 1.53382159315339 0.376143473427112 0.769121026192099 GO:0060175 brain-derived neurotrophic factor receptor activity 2/496 49/18639 0.0408163265306122 1.53382159315339 0.376143473427112 0.769121026192099 GO:0005254 chloride channel activity 3/496 83/18639 0.036144578313253 1.35826369996113 0.380473171099265 0.769121026192099 GO:0008135 translation factor activity, RNA binding 3/496 83/18639 0.036144578313253 1.35826369996113 0.380473171099265 0.769121026192099 GO:0030165 PDZ domain binding 3/496 83/18639 0.036144578313253 1.35826369996113 0.380473171099265 0.769121026192099 GO:0000900 mRNA regulatory element binding translation repressor activity 1/496 18/18639 0.0555555555555556 2.08770161290323 0.384739068674454 0.769121026192099 GO:0008525 phosphatidylcholine transporter activity 1/496 18/18639 0.0555555555555556 2.08770161290323 0.384739068674454 0.769121026192099 GO:0015373 monoatomic anion:sodium symporter activity 1/496 18/18639 0.0555555555555556 2.08770161290323 0.384739068674454 0.769121026192099 GO:0016854 racemase and epimerase activity 1/496 18/18639 0.0555555555555556 2.08770161290323 0.384739068674454 0.769121026192099 GO:0030228 lipoprotein particle receptor activity 1/496 18/18639 0.0555555555555556 2.08770161290323 0.384739068674454 0.769121026192099 GO:0035615 clathrin adaptor activity 1/496 18/18639 0.0555555555555556 2.08770161290323 0.384739068674454 0.769121026192099 GO:0099602 neurotransmitter receptor regulator activity 1/496 18/18639 0.0555555555555556 2.08770161290323 0.384739068674454 0.769121026192099 GO:0005007 fibroblast growth factor receptor activity 2/496 50/18639 0.04 1.50314516129032 0.385665572041728 0.769121026192099 GO:0005017 platelet-derived growth factor receptor activity 2/496 50/18639 0.04 1.50314516129032 0.385665572041728 0.769121026192099 GO:0005019 platelet-derived growth factor beta-receptor activity 2/496 50/18639 0.04 1.50314516129032 0.385665572041728 0.769121026192099 GO:0048020 CCR chemokine receptor binding 2/496 50/18639 0.04 1.50314516129032 0.385665572041728 0.769121026192099 GO:0180051 translation factor activity 3/496 84/18639 0.0357142857142857 1.34209389400922 0.387705671122009 0.770980420288338 GO:0046982 protein heterodimerization activity 11/496 369/18639 0.029810298102981 1.12023013375295 0.393797605673931 0.774665226580322 GO:0005010 insulin-like growth factor receptor activity 2/496 51/18639 0.0392156862745098 1.47367172675522 0.395123786545998 0.774665226580322 GO:0005021 vascular endothelial growth factor receptor activity 2/496 51/18639 0.0392156862745098 1.47367172675522 0.395123786545998 0.774665226580322 GO:0005030 neurotrophin receptor activity 2/496 51/18639 0.0392156862745098 1.47367172675522 0.395123786545998 0.774665226580322 GO:0030544 Hsp70 protein binding 2/496 51/18639 0.0392156862745098 1.47367172675522 0.395123786545998 0.774665226580322 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/496 19/18639 0.0526315789473684 1.97782258064516 0.401127523748696 0.777673416515578 GO:0030506 ankyrin binding 1/496 19/18639 0.0526315789473684 1.97782258064516 0.401127523748696 0.777673416515578 GO:0046624 sphingolipid transporter activity 1/496 19/18639 0.0526315789473684 1.97782258064516 0.401127523748696 0.777673416515578 GO:0097001 ceramide binding 1/496 19/18639 0.0526315789473684 1.97782258064516 0.401127523748696 0.777673416515578 GO:0015108 chloride transmembrane transporter activity 4/496 121/18639 0.0330578512396694 1.24226872833911 0.402703456661128 0.778560016211514 GO:0008528 G protein-coupled peptide receptor activity 4/496 122/18639 0.0327868852459016 1.23208619777895 0.408713756632922 0.780343792565121 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/496 122/18639 0.0327868852459016 1.23208619777895 0.408713756632922 0.780343792565121 GO:0000287 magnesium ion binding 7/496 230/18639 0.0304347826086957 1.14369740532959 0.413390663543687 0.780343792565121 GO:0005003 ephrin receptor activity 2/496 53/18639 0.0377358490566038 1.4180614729154 0.413835413218239 0.780343792565121 GO:0005005 transmembrane-ephrin receptor activity 2/496 53/18639 0.0377358490566038 1.4180614729154 0.413835413218239 0.780343792565121 GO:0005246 calcium channel regulator activity 2/496 53/18639 0.0377358490566038 1.4180614729154 0.413835413218239 0.780343792565121 GO:0005544 calcium-dependent phospholipid binding 2/496 53/18639 0.0377358490566038 1.4180614729154 0.413835413218239 0.780343792565121 GO:0038064 collagen receptor activity 2/496 53/18639 0.0377358490566038 1.4180614729154 0.413835413218239 0.780343792565121 GO:0051018 protein kinase A binding 2/496 53/18639 0.0377358490566038 1.4180614729154 0.413835413218239 0.780343792565121 GO:0001972 retinoic acid binding 1/496 20/18639 0.05 1.8789314516129 0.417080302922737 0.780343792565121 GO:0015095 magnesium ion transmembrane transporter activity 1/496 20/18639 0.05 1.8789314516129 0.417080302922737 0.780343792565121 GO:0043024 ribosomal small subunit binding 1/496 20/18639 0.05 1.8789314516129 0.417080302922737 0.780343792565121 GO:0003925 G protein activity 2/496 54/18639 0.037037037037037 1.39180107526882 0.423082796898374 0.788209005323991 GO:0140297 DNA-binding transcription factor binding 14/496 488/18639 0.0286885245901639 1.07807542305658 0.425333883252088 0.788209005323991 GO:0140313 molecular sequestering activity 2/496 55/18639 0.0363636363636364 1.36649560117302 0.43225422098302 0.788209005323991 GO:0001846 opsonin binding 1/496 21/18639 0.0476190476190476 1.78945852534562 0.432608965565753 0.788209005323991 GO:0015174 basic amino acid transmembrane transporter activity 1/496 21/18639 0.0476190476190476 1.78945852534562 0.432608965565753 0.788209005323991 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/496 21/18639 0.0476190476190476 1.78945852534562 0.432608965565753 0.788209005323991 GO:0051010 microtubule plus-end binding 1/496 21/18639 0.0476190476190476 1.78945852534562 0.432608965565753 0.788209005323991 GO:0051428 peptide hormone receptor binding 1/496 21/18639 0.0476190476190476 1.78945852534562 0.432608965565753 0.788209005323991 GO:0061891 calcium ion sensor activity 1/496 21/18639 0.0476190476190476 1.78945852534562 0.432608965565753 0.788209005323991 GO:0140312 cargo adaptor activity 1/496 21/18639 0.0476190476190476 1.78945852534562 0.432608965565753 0.788209005323991 GO:0001653 peptide receptor activity 4/496 128/18639 0.03125 1.17433215725806 0.444477960202179 0.803135145388052 GO:0043178 alcohol binding 3/496 92/18639 0.0326086956521739 1.22539007713885 0.444668582684693 0.803135145388052 GO:0005243 gap junction channel activity 1/496 22/18639 0.0454545454545455 1.70811950146628 0.447724764957707 0.803135145388052 GO:0015377 chloride:monoatomic cation symporter activity 1/496 22/18639 0.0454545454545455 1.70811950146628 0.447724764957707 0.803135145388052 GO:0031683 G-protein beta/gamma-subunit complex binding 1/496 22/18639 0.0454545454545455 1.70811950146628 0.447724764957707 0.803135145388052 GO:0140784 metal ion sensor activity 1/496 22/18639 0.0454545454545455 1.70811950146628 0.447724764957707 0.803135145388052 GO:0005543 phospholipid binding 14/496 497/18639 0.028169014084507 1.05855293048614 0.452366431571756 0.804643262098597 GO:0016298 lipase activity 4/496 130/18639 0.0307692307692308 1.15626550868486 0.456258798037429 0.804643262098597 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 4/496 130/18639 0.0307692307692308 1.15626550868486 0.456258798037429 0.804643262098597 GO:0017116 single-stranded DNA helicase activity 2/496 58/18639 0.0344827586206897 1.2958147942158 0.459288573075095 0.804643262098597 GO:0061980 regulatory RNA binding 2/496 58/18639 0.0344827586206897 1.2958147942158 0.459288573075095 0.804643262098597 GO:0003714 transcription corepressor activity 6/496 204/18639 0.0294117647058824 1.10525379506641 0.460188052731312 0.804643262098597 GO:0000295 adenine nucleotide transmembrane transporter activity 1/496 23/18639 0.0434782608695652 1.63385343618513 0.462438656378504 0.804643262098597 GO:0005212 structural constituent of eye lens 1/496 23/18639 0.0434782608695652 1.63385343618513 0.462438656378504 0.804643262098597 GO:0005283 amino acid:sodium symporter activity 1/496 23/18639 0.0434782608695652 1.63385343618513 0.462438656378504 0.804643262098597 GO:0031681 G-protein beta-subunit binding 1/496 23/18639 0.0434782608695652 1.63385343618513 0.462438656378504 0.804643262098597 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/496 23/18639 0.0434782608695652 1.63385343618513 0.462438656378504 0.804643262098597 GO:0140103 catalytic activity, acting on a glycoprotein 1/496 23/18639 0.0434782608695652 1.63385343618513 0.462438656378504 0.804643262098597 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4/496 132/18639 0.0303030303030303 1.13874633431085 0.467955279691797 0.806486377704966 GO:0001786 phosphatidylserine binding 2/496 59/18639 0.0338983050847458 1.27385183160197 0.468132897403457 0.806486377704966 GO:0036002 pre-mRNA binding 2/496 59/18639 0.0338983050847458 1.27385183160197 0.468132897403457 0.806486377704966 GO:0045309 protein phosphorylated amino acid binding 2/496 59/18639 0.0338983050847458 1.27385183160197 0.468132897403457 0.806486377704966 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/496 24/18639 0.0416666666666667 1.56577620967742 0.476761304983804 0.80736220989958 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/496 24/18639 0.0416666666666667 1.56577620967742 0.476761304983804 0.80736220989958 GO:0015149 hexose transmembrane transporter activity 1/496 24/18639 0.0416666666666667 1.56577620967742 0.476761304983804 0.80736220989958 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/496 24/18639 0.0416666666666667 1.56577620967742 0.476761304983804 0.80736220989958 GO:0050431 transforming growth factor beta binding 1/496 24/18639 0.0416666666666667 1.56577620967742 0.476761304983804 0.80736220989958 GO:0055056 D-glucose transmembrane transporter activity 1/496 24/18639 0.0416666666666667 1.56577620967742 0.476761304983804 0.80736220989958 GO:0070840 dynein complex binding 1/496 24/18639 0.0416666666666667 1.56577620967742 0.476761304983804 0.80736220989958 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/496 61/18639 0.0327868852459016 1.23208619777895 0.485559742991502 0.813165126326832 GO:0004725 protein tyrosine phosphatase activity 3/496 98/18639 0.0306122448979592 1.15036619486504 0.485986144182814 0.813165126326832 GO:0042626 ATPase-coupled transmembrane transporter activity 3/496 98/18639 0.0306122448979592 1.15036619486504 0.485986144182814 0.813165126326832 GO:0001848 complement binding 1/496 25/18639 0.04 1.50314516129032 0.490703093473088 0.813165126326832 GO:0003707 nuclear steroid receptor activity 1/496 25/18639 0.04 1.50314516129032 0.490703093473088 0.813165126326832 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/496 25/18639 0.04 1.50314516129032 0.490703093473088 0.813165126326832 GO:0015645 fatty acid ligase activity 1/496 25/18639 0.04 1.50314516129032 0.490703093473088 0.813165126326832 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/496 25/18639 0.04 1.50314516129032 0.490703093473088 0.813165126326832 GO:0120515 fatty acid-CoA ligase activity 1/496 25/18639 0.04 1.50314516129032 0.490703093473088 0.813165126326832 GO:0015179 L-amino acid transmembrane transporter activity 2/496 62/18639 0.032258064516129 1.21221383975026 0.494139105853759 0.814326668609289 GO:0003823 antigen binding 5/496 174/18639 0.028735632183908 1.0798456618465 0.494558454492345 0.814326668609289 GO:1901682 sulfur compound transmembrane transporter activity 2/496 63/18639 0.0317460317460317 1.19297235023041 0.502627231356711 0.814326668609289 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/496 26/18639 0.0384615384615385 1.44533188585608 0.504274129555465 0.814326668609289 GO:0005160 transforming growth factor beta receptor binding 1/496 26/18639 0.0384615384615385 1.44533188585608 0.504274129555465 0.814326668609289 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/496 26/18639 0.0384615384615385 1.44533188585608 0.504274129555465 0.814326668609289 GO:0015145 monosaccharide transmembrane transporter activity 1/496 26/18639 0.0384615384615385 1.44533188585608 0.504274129555465 0.814326668609289 GO:0015216 purine nucleotide transmembrane transporter activity 1/496 26/18639 0.0384615384615385 1.44533188585608 0.504274129555465 0.814326668609289 GO:0019865 immunoglobulin binding 1/496 26/18639 0.0384615384615385 1.44533188585608 0.504274129555465 0.814326668609289 GO:0030247 polysaccharide binding 1/496 26/18639 0.0384615384615385 1.44533188585608 0.504274129555465 0.814326668609289 GO:0097602 cullin family protein binding 1/496 26/18639 0.0384615384615385 1.44533188585608 0.504274129555465 0.814326668609289 GO:0070851 growth factor receptor binding 4/496 139/18639 0.0287769784172662 1.08139939661174 0.50812041167387 0.818638441030123 GO:0015171 amino acid transmembrane transporter activity 3/496 102/18639 0.0294117647058824 1.10525379506641 0.51269289977108 0.822303744840391 GO:0005044 scavenger receptor activity 1/496 27/18639 0.037037037037037 1.39180107526882 0.517484253218522 0.822303744840391 GO:0008395 steroid hydroxylase activity 1/496 27/18639 0.037037037037037 1.39180107526882 0.517484253218522 0.822303744840391 GO:0016405 CoA-ligase activity 1/496 27/18639 0.037037037037037 1.39180107526882 0.517484253218522 0.822303744840391 GO:0023026 MHC class II protein complex binding 1/496 27/18639 0.037037037037037 1.39180107526882 0.517484253218522 0.822303744840391 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/496 27/18639 0.037037037037037 1.39180107526882 0.517484253218522 0.822303744840391 GO:0005253 monoatomic anion channel activity 3/496 103/18639 0.029126213592233 1.09452317569684 0.519254374068443 0.823237003078898 GO:0008235 metalloexopeptidase activity 2/496 66/18639 0.0303030303030303 1.13874633431085 0.527532557802414 0.829480356154117 GO:0016866 intramolecular transferase activity 1/496 28/18639 0.0357142857142857 1.34209389400922 0.530343043805434 0.829480356154117 GO:0045499 chemorepellent activity 1/496 28/18639 0.0357142857142857 1.34209389400922 0.530343043805434 0.829480356154117 GO:0046875 ephrin receptor binding 1/496 28/18639 0.0357142857142857 1.34209389400922 0.530343043805434 0.829480356154117 GO:0051119 sugar transmembrane transporter activity 1/496 28/18639 0.0357142857142857 1.34209389400922 0.530343043805434 0.829480356154117 GO:0051393 alpha-actinin binding 1/496 28/18639 0.0357142857142857 1.34209389400922 0.530343043805434 0.829480356154117 GO:0004629 phospholipase C activity 1/496 29/18639 0.0344827586206897 1.2958147942158 0.542859826905349 0.845258253973429 GO:0005416 amino acid:monoatomic cation symporter activity 1/496 29/18639 0.0344827586206897 1.2958147942158 0.542859826905349 0.845258253973429 GO:0008237 metallopeptidase activity 5/496 184/18639 0.0271739130434783 1.02115839761571 0.544093428659726 0.845288005239217 GO:1901981 phosphatidylinositol phosphate binding 5/496 185/18639 0.027027027027027 1.01563862249346 0.548922540932577 0.849267436815787 GO:0003730 mRNA 3'-UTR binding 7/496 262/18639 0.0267175572519084 1.00400917261758 0.549095325527449 0.849267436815787 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/496 30/18639 0.0333333333333333 1.25262096774194 0.555043681061982 0.854669031015795 GO:0015215 nucleotide transmembrane transporter activity 1/496 30/18639 0.0333333333333333 1.25262096774194 0.555043681061982 0.854669031015795 GO:0008509 monoatomic anion transmembrane transporter activity 4/496 149/18639 0.0268456375838926 1.00882225589955 0.562986044735794 0.863500618455199 GO:0046943 carboxylic acid transmembrane transporter activity 5/496 188/18639 0.0265957446808511 0.999431623198353 0.56326046088888 0.863500618455199 GO:0008327 methyl-CpG binding 1/496 31/18639 0.032258064516129 1.21221383975026 0.566903444305211 0.865032831400731 GO:0016878 acid-thiol ligase activity 1/496 31/18639 0.032258064516129 1.21221383975026 0.566903444305211 0.865032831400731 GO:0005342 organic acid transmembrane transporter activity 5/496 189/18639 0.0264550264550265 0.994143625192012 0.567988511422606 0.865032831400731 GO:0019902 phosphatase binding 5/496 190/18639 0.0263157894736842 0.988911290322581 0.572690244448946 0.865805620376734 GO:0008514 organic anion transmembrane transporter activity 7/496 269/18639 0.0260223048327138 0.977882539872886 0.57709303433151 0.865805620376734 GO:0031369 translation initiation factor binding 1/496 32/18639 0.03125 1.17433215725806 0.578447720510318 0.865805620376734 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/496 32/18639 0.03125 1.17433215725806 0.578447720510318 0.865805620376734 GO:0043425 bHLH transcription factor binding 1/496 32/18639 0.03125 1.17433215725806 0.578447720510318 0.865805620376734 GO:0051059 NF-kappaB binding 1/496 32/18639 0.03125 1.17433215725806 0.578447720510318 0.865805620376734 GO:0071813 lipoprotein particle binding 1/496 32/18639 0.03125 1.17433215725806 0.578447720510318 0.865805620376734 GO:0071814 protein-lipid complex binding 1/496 32/18639 0.03125 1.17433215725806 0.578447720510318 0.865805620376734 GO:0019239 deaminase activity 1/496 33/18639 0.0303030303030303 1.13874633431085 0.589684885589421 0.877003655574958 GO:0030296 protein tyrosine kinase activator activity 1/496 33/18639 0.0303030303030303 1.13874633431085 0.589684885589421 0.877003655574958 GO:0003678 DNA helicase activity 2/496 74/18639 0.027027027027027 1.01563862249346 0.589709354610748 0.877003655574958 GO:0001221 transcription coregulator binding 3/496 115/18639 0.0260869565217391 0.98031206171108 0.594024278751982 0.877560592415072 GO:0017124 SH3 domain binding 3/496 115/18639 0.0260869565217391 0.98031206171108 0.594024278751982 0.877560592415072 GO:0015035 protein-disulfide reductase activity 1/496 34/18639 0.0294117647058824 1.10525379506641 0.600623093519532 0.877560592415072 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/496 34/18639 0.0294117647058824 1.10525379506641 0.600623093519532 0.877560592415072 GO:0051427 hormone receptor binding 1/496 34/18639 0.0294117647058824 1.10525379506641 0.600623093519532 0.877560592415072 GO:0051020 GTPase binding 8/496 315/18639 0.0253968253968254 0.954377880184332 0.603044970347328 0.877560592415072 GO:0051536 iron-sulfur cluster binding 2/496 76/18639 0.0263157894736842 0.988911290322581 0.604271951488717 0.877560592415072 GO:1990782 protein tyrosine kinase binding 3/496 117/18639 0.0256410256410256 0.96355459057072 0.605729829190166 0.877560592415072 GO:0005343 organic acid:sodium symporter activity 1/496 35/18639 0.0285714285714286 1.07367511520737 0.611270282211514 0.877560592415072 GO:0016229 steroid dehydrogenase activity 1/496 35/18639 0.0285714285714286 1.07367511520737 0.611270282211514 0.877560592415072 GO:0016829 lyase activity 5/496 200/18639 0.025 0.939465725806452 0.618180575410601 0.877560592415072 GO:0004033 aldo-keto reductase (NADPH) activity 1/496 36/18639 0.0277777777777778 1.04385080645161 0.62163417922415 0.877560592415072 GO:0004190 aspartic-type endopeptidase activity 1/496 36/18639 0.0277777777777778 1.04385080645161 0.62163417922415 0.877560592415072 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/496 36/18639 0.0277777777777778 1.04385080645161 0.62163417922415 0.877560592415072 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/496 36/18639 0.0277777777777778 1.04385080645161 0.62163417922415 0.877560592415072 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/496 36/18639 0.0277777777777778 1.04385080645161 0.62163417922415 0.877560592415072 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/496 36/18639 0.0277777777777778 1.04385080645161 0.62163417922415 0.877560592415072 GO:0015370 solute:sodium symporter activity 2/496 79/18639 0.0253164556962025 0.951357697019191 0.625376817918681 0.877560592415072 GO:0008083 growth factor activity 4/496 162/18639 0.0246913580246914 0.927867383512545 0.629002088247868 0.877560592415072 GO:0023023 MHC protein complex binding 1/496 37/18639 0.027027027027027 1.01563862249346 0.631722307327404 0.877560592415072 GO:0030280 structural constituent of skin epidermis 1/496 37/18639 0.027027027027027 1.01563862249346 0.631722307327404 0.877560592415072 GO:0043394 proteoglycan binding 1/496 37/18639 0.027027027027027 1.01563862249346 0.631722307327404 0.877560592415072 GO:0070001 aspartic-type peptidase activity 1/496 37/18639 0.027027027027027 1.01563862249346 0.631722307327404 0.877560592415072 GO:0000049 tRNA binding 2/496 80/18639 0.025 0.939465725806452 0.632215347632405 0.877560592415072 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/496 122/18639 0.0245901639344262 0.924064648334215 0.634001399651553 0.877560592415072 GO:0035091 phosphatidylinositol binding 7/496 284/18639 0.0246478873239437 0.926233814175375 0.634111746200575 0.877560592415072 GO:0030971 receptor tyrosine kinase binding 2/496 81/18639 0.0246913580246914 0.927867383512545 0.638956110169586 0.877560592415072 GO:0033192 calmodulin-dependent protein phosphatase activity 2/496 81/18639 0.0246913580246914 0.927867383512545 0.638956110169586 0.877560592415072 GO:0140791 histone H2AXS140 phosphatase activity 2/496 81/18639 0.0246913580246914 0.927867383512545 0.638956110169586 0.877560592415072 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/496 81/18639 0.0246913580246914 0.927867383512545 0.638956110169586 0.877560592415072 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/496 81/18639 0.0246913580246914 0.927867383512545 0.638956110169586 0.877560592415072 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/496 81/18639 0.0246913580246914 0.927867383512545 0.638956110169586 0.877560592415072 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/496 81/18639 0.0246913580246914 0.927867383512545 0.638956110169586 0.877560592415072 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/496 81/18639 0.0246913580246914 0.927867383512545 0.638956110169586 0.877560592415072 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/496 81/18639 0.0246913580246914 0.927867383512545 0.638956110169586 0.877560592415072 GO:0000146 microfilament motor activity 1/496 38/18639 0.0263157894736842 0.988911290322581 0.641541989918824 0.877560592415072 GO:0042162 telomeric DNA binding 1/496 38/18639 0.0263157894736842 0.988911290322581 0.641541989918824 0.877560592415072 GO:0042887 amide transmembrane transporter activity 1/496 38/18639 0.0263157894736842 0.988911290322581 0.641541989918824 0.877560592415072 GO:0015103 inorganic anion transmembrane transporter activity 4/496 165/18639 0.0242424242424242 0.91099706744868 0.643299883668328 0.877560592415072 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/496 82/18639 0.024390243902439 0.91655192761605 0.645599455285036 0.877560592415072 GO:0033549 MAP kinase phosphatase activity 2/496 82/18639 0.024390243902439 0.91655192761605 0.645599455285036 0.877560592415072 GO:0015399 primary active transmembrane transporter activity 4/496 166/18639 0.0240963855421687 0.905509133307423 0.647984735411091 0.877560592415072 GO:0005516 calmodulin binding 5/496 207/18639 0.0241545893719807 0.907696353436185 0.648265296946452 0.877560592415072 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/496 39/18639 0.0256410256410256 0.96355459057072 0.65110035629699 0.877560592415072 GO:0001540 amyloid-beta binding 2/496 83/18639 0.0240963855421687 0.905509133307423 0.652145783289623 0.877560592415072 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/496 83/18639 0.0240963855421687 0.905509133307423 0.652145783289623 0.877560592415072 GO:0003924 GTPase activity 8/496 331/18639 0.0241691842900302 0.908244810447325 0.658119484845471 0.877560592415072 GO:0017018 myosin phosphatase activity 2/496 84/18639 0.0238095238095238 0.894729262672811 0.658595542122979 0.877560592415072 GO:0015036 disulfide oxidoreductase activity 1/496 40/18639 0.025 0.939465725806452 0.660404346795737 0.877560592415072 GO:0015144 carbohydrate transmembrane transporter activity 1/496 40/18639 0.025 0.939465725806452 0.660404346795737 0.877560592415072 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/496 40/18639 0.025 0.939465725806452 0.660404346795737 0.877560592415072 GO:0050997 quaternary ammonium group binding 1/496 40/18639 0.025 0.939465725806452 0.660404346795737 0.877560592415072 GO:0061791 GTPase motor activity 1/496 40/18639 0.025 0.939465725806452 0.660404346795737 0.877560592415072 GO:0140662 ATP-dependent protein folding chaperone 1/496 40/18639 0.025 0.939465725806452 0.660404346795737 0.877560592415072 GO:1990606 membrane scission GTPase motor activity 1/496 40/18639 0.025 0.939465725806452 0.660404346795737 0.877560592415072 GO:0008094 ATP-dependent activity, acting on DNA 5/496 210/18639 0.0238095238095238 0.894729262672811 0.660692170151577 0.877560592415072 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/496 41/18639 0.024390243902439 0.91655192761605 0.66946071778285 0.885826349005444 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/496 41/18639 0.024390243902439 0.91655192761605 0.66946071778285 0.885826349005444 GO:0008081 phosphoric diester hydrolase activity 2/496 87/18639 0.0229885057471264 0.863876529477197 0.677370539261115 0.88903978979782 GO:0004520 DNA endonuclease activity 1/496 42/18639 0.0238095238095238 0.894729262672811 0.678276046526785 0.88903978979782 GO:0016859 cis-trans isomerase activity 1/496 42/18639 0.0238095238095238 0.894729262672811 0.678276046526785 0.88903978979782 GO:0043175 RNA polymerase core enzyme binding 1/496 42/18639 0.0238095238095238 0.894729262672811 0.678276046526785 0.88903978979782 GO:0051879 Hsp90 protein binding 1/496 42/18639 0.0238095238095238 0.894729262672811 0.678276046526785 0.88903978979782 GO:0031072 heat shock protein binding 3/496 131/18639 0.0229007633587786 0.86057929081507 0.681255805356139 0.891266993473445 GO:0008375 acetylglucosaminyltransferase activity 1/496 43/18639 0.0232558139534884 0.87392160540135 0.6868567359349 0.891881911875271 GO:0048156 tau protein binding 1/496 43/18639 0.0232558139534884 0.87392160540135 0.6868567359349 0.891881911875271 GO:0004721 phosphoprotein phosphatase activity 4/496 175/18639 0.0228571428571429 0.858940092165899 0.688294754847889 0.891881911875271 GO:0003727 single-stranded RNA binding 2/496 89/18639 0.0224719101123595 0.844463573758608 0.689414466363356 0.891881911875271 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/496 89/18639 0.0224719101123595 0.844463573758608 0.689414466363356 0.891881911875271 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/496 89/18639 0.0224719101123595 0.844463573758608 0.689414466363356 0.891881911875271 GO:0004252 serine-type endopeptidase activity 4/496 176/18639 0.0227272727272727 0.854059750733138 0.692565945974647 0.892853127251443 GO:0001046 core promoter sequence-specific DNA binding 1/496 44/18639 0.0227272727272727 0.854059750733138 0.695209019166578 0.892853127251443 GO:0019205 nucleobase-containing compound kinase activity 1/496 44/18639 0.0227272727272727 0.854059750733138 0.695209019166578 0.892853127251443 GO:0140793 histone H2AXY142 phosphatase activity 2/496 90/18639 0.0222222222222222 0.83508064516129 0.695296544497532 0.892853127251443 GO:0015297 antiporter activity 3/496 135/18639 0.0222222222222222 0.83508064516129 0.700751016802892 0.898200198332988 GO:0140303 intramembrane lipid transporter activity 1/496 45/18639 0.0222222222222222 0.83508064516129 0.703338964124544 0.89986014527699 GO:0140789 histone phosphatase activity 3/496 136/18639 0.0220588235294118 0.82894034629981 0.705480787311478 0.900944271502364 GO:0052689 carboxylic ester hydrolase activity 2/496 92/18639 0.0217391304347826 0.816926718092567 0.706784472304311 0.900956030629671 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/496 46/18639 0.0217391304347826 0.816926718092567 0.711252477827579 0.90149946964189 GO:0030276 clathrin binding 1/496 46/18639 0.0217391304347826 0.816926718092567 0.711252477827579 0.90149946964189 GO:0051213 dioxygenase activity 2/496 93/18639 0.021505376344086 0.808142559833507 0.712391822274482 0.90149946964189 GO:0051219 phosphoprotein binding 2/496 93/18639 0.021505376344086 0.808142559833507 0.712391822274482 0.90149946964189 GO:0001784 phosphotyrosine residue binding 1/496 47/18639 0.0212765957446809 0.799545298558682 0.718955310667762 0.902877375261566 GO:0061749 forked DNA-dependent helicase activity 1/496 47/18639 0.0212765957446809 0.799545298558682 0.718955310667762 0.902877375261566 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/496 47/18639 0.0212765957446809 0.799545298558682 0.718955310667762 0.902877375261566 GO:0140767 enzyme-substrate adaptor activity 3/496 139/18639 0.0215827338129496 0.811049547458807 0.719327002037816 0.902877375261566 GO:0009378 four-way junction helicase activity 1/496 48/18639 0.0208333333333333 0.78288810483871 0.726453060555283 0.902877375261566 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/496 48/18639 0.0208333333333333 0.78288810483871 0.726453060555283 0.902877375261566 GO:0036121 double-stranded DNA helicase activity 1/496 48/18639 0.0208333333333333 0.78288810483871 0.726453060555283 0.902877375261566 GO:0038187 pattern recognition receptor activity 1/496 48/18639 0.0208333333333333 0.78288810483871 0.726453060555283 0.902877375261566 GO:0043138 3'-5' DNA helicase activity 1/496 48/18639 0.0208333333333333 0.78288810483871 0.726453060555283 0.902877375261566 GO:0140693 molecular condensate scaffold activity 1/496 48/18639 0.0208333333333333 0.78288810483871 0.726453060555283 0.902877375261566 GO:0005096 GTPase activator activity 6/496 271/18639 0.022140221402214 0.831999166765861 0.731003453519833 0.906913375489846 GO:0015605 organophosphate ester transmembrane transporter activity 1/496 50/18639 0.02 0.751572580645161 0.740854964809135 0.916387807790964 GO:0019903 protein phosphatase binding 3/496 144/18639 0.0208333333333333 0.78288810483871 0.741273470957346 0.916387807790964 GO:0003743 translation initiation factor activity 1/496 51/18639 0.0196078431372549 0.736835863377609 0.747769588374397 0.919518787117634 GO:0016597 amino acid binding 1/496 51/18639 0.0196078431372549 0.736835863377609 0.747769588374397 0.919518787117634 GO:0016830 carbon-carbon lyase activity 1/496 51/18639 0.0196078431372549 0.736835863377609 0.747769588374397 0.919518787117634 GO:0043130 ubiquitin binding 2/496 100/18639 0.02 0.751572580645161 0.749169033043765 0.919614897704516 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/496 52/18639 0.0192307692307692 0.72266594292804 0.754500074933807 0.924528260834383 GO:0008238 exopeptidase activity 2/496 102/18639 0.0196078431372549 0.736835863377609 0.758907573961793 0.927578734011884 GO:0008146 sulfotransferase activity 1/496 53/18639 0.0188679245283019 0.709030736457699 0.761051318428337 0.927578734011884 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/496 53/18639 0.0188679245283019 0.709030736457699 0.761051318428337 0.927578734011884 GO:0008236 serine-type peptidase activity 4/496 194/18639 0.0206185567010309 0.77481709344862 0.762350075183936 0.927578734011884 GO:0004722 protein serine/threonine phosphatase activity 2/496 103/18639 0.0194174757281553 0.729682117131225 0.763653181880473 0.927578734011884 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/496 54/18639 0.0185185185185185 0.695900537634409 0.767428082985506 0.92763803764506 GO:0050661 NADP binding 1/496 54/18639 0.0185185185185185 0.695900537634409 0.767428082985506 0.92763803764506 GO:0031267 small GTPase binding 6/496 283/18639 0.0212014134275618 0.796720050153881 0.767700444947636 0.92763803764506 GO:0008374 O-acyltransferase activity 1/496 55/18639 0.0181818181818182 0.68324780058651 0.773635006355922 0.931675495984121 GO:0017171 serine hydrolase activity 4/496 198/18639 0.0202020202020202 0.7591642228739 0.776063416425044 0.931675495984121 GO:0004497 monooxygenase activity 2/496 106/18639 0.0188679245283019 0.709030736457699 0.777406680029444 0.931675495984121 GO:0008013 beta-catenin binding 2/496 106/18639 0.0188679245283019 0.709030736457699 0.777406680029444 0.931675495984121 GO:0022804 active transmembrane transporter activity 10/496 457/18639 0.0218818380743982 0.822289475541752 0.778257070920944 0.931675495984121 GO:0015291 secondary active transmembrane transporter activity 6/496 287/18639 0.0209059233449477 0.785615937956615 0.77907347509017 0.931675495984121 GO:0004386 helicase activity 3/496 155/18639 0.0193548387096774 0.727328303850156 0.784742912869694 0.934611724741503 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/496 57/18639 0.0175438596491228 0.659274193548387 0.785557268640488 0.934611724741503 GO:0016504 peptidase activator activity 1/496 57/18639 0.0175438596491228 0.659274193548387 0.785557268640488 0.934611724741503 GO:0005525 GTP binding 8/496 378/18639 0.0211640211640212 0.79531490015361 0.79144445777006 0.940009117078433 GO:0042277 peptide binding 5/496 249/18639 0.0200803212851406 0.754590944422853 0.795718682232459 0.940016189946234 GO:0015459 potassium channel regulator activity 1/496 59/18639 0.0169491525423729 0.636925915800984 0.796852804695802 0.940016189946234 GO:0070063 RNA polymerase binding 1/496 59/18639 0.0169491525423729 0.636925915800984 0.796852804695802 0.940016189946234 GO:0070888 E-box binding 1/496 59/18639 0.0169491525423729 0.636925915800984 0.796852804695802 0.940016189946234 GO:1902936 phosphatidylinositol bisphosphate binding 2/496 111/18639 0.018018018018018 0.677092414995641 0.798775810757652 0.940690294902413 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/496 60/18639 0.0166666666666667 0.626310483870968 0.802275894516624 0.942270604879359 GO:0043022 ribosome binding 2/496 112/18639 0.0178571428571429 0.671046947004608 0.802825386053821 0.942270604879359 GO:0015294 solute:monoatomic cation symporter activity 2/496 116/18639 0.0172413793103448 0.647907397107898 0.818308808217505 0.958826482355865 GO:0004536 DNA nuclease activity 1/496 64/18639 0.015625 0.587166078629032 0.822561293773143 0.962189345321189 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 7/496 349/18639 0.0200573065902579 0.753726083741566 0.824334458153618 0.962645608850534 GO:0032182 ubiquitin-like protein binding 2/496 120/18639 0.0166666666666667 0.626310483870968 0.832695292274038 0.967232104296704 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/496 67/18639 0.0149253731343284 0.560875060182956 0.836400043192792 0.967232104296704 GO:0019001 guanyl nucleotide binding 8/496 400/18639 0.02 0.751572580645161 0.838776803351543 0.967232104296704 GO:0032561 guanyl ribonucleotide binding 8/496 400/18639 0.02 0.751572580645161 0.838776803351543 0.967232104296704 GO:0045182 translation regulator activity 7/496 356/18639 0.0196629213483146 0.738905627038782 0.839176414778732 0.967232104296704 GO:0005548 phospholipid transporter activity 1/496 68/18639 0.0147058823529412 0.552626897533207 0.840769286062508 0.967232104296704 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/496 68/18639 0.0147058823529412 0.552626897533207 0.840769286062508 0.967232104296704 GO:0030145 manganese ion binding 1/496 68/18639 0.0147058823529412 0.552626897533207 0.840769286062508 0.967232104296704 GO:1990841 promoter-specific chromatin binding 1/496 68/18639 0.0147058823529412 0.552626897533207 0.840769286062508 0.967232104296704 GO:0035173 histone kinase activity 7/496 360/18639 0.0194444444444444 0.730695564516129 0.847199856090603 0.972066442988746 GO:0004175 endopeptidase activity 8/496 405/18639 0.0197530864197531 0.742293906810036 0.848263747223009 0.972066442988746 GO:0016782 transferase activity, transferring sulphur-containing groups 1/496 70/18639 0.0142857142857143 0.536837557603687 0.849161490426951 0.972066442988746 GO:0140299 molecular sensor activity 1/496 71/18639 0.0140845070422535 0.529276465243071 0.853190565807867 0.973965011208804 GO:0043021 ribonucleoprotein complex binding 3/496 177/18639 0.0169491525423729 0.636925915800984 0.853618759823808 0.973965011208804 GO:0042826 histone deacetylase binding 2/496 127/18639 0.015748031496063 0.591789433578867 0.855417665134556 0.974420122641 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3/496 181/18639 0.0165745856353591 0.622850204954553 0.863841486760507 0.981717294523767 GO:0048029 monosaccharide binding 1/496 74/18639 0.0135135135135135 0.507819311246731 0.8646446861251 0.981717294523767 GO:0019003 GDP binding 1/496 75/18639 0.0133333333333333 0.501048387096774 0.868260965989465 0.982617288339297 GO:0044183 protein folding chaperone 1/496 75/18639 0.0133333333333333 0.501048387096774 0.868260965989465 0.982617288339297 GO:0015078 proton transmembrane transporter activity 3/496 185/18639 0.0162162162162162 0.609383173496077 0.873432023997068 0.986864754386297 GO:0016835 carbon-oxygen lyase activity 1/496 79/18639 0.0126582278481013 0.475678848509596 0.8817871441545 0.992855266936521 GO:0046332 SMAD binding 1/496 79/18639 0.0126582278481013 0.475678848509596 0.8817871441545 0.992855266936521 GO:0016922 nuclear receptor binding 2/496 137/18639 0.0145985401459854 0.548593124558512 0.883013520450728 0.992855266936521 GO:0140097 catalytic activity, acting on DNA 6/496 336/18639 0.0178571428571429 0.671046947004608 0.886185606153083 0.994814809487977 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/496 86/18639 0.0116279069767442 0.436960802700675 0.902208100359611 0.999572226578691 GO:0015293 symporter activity 2/496 146/18639 0.0136986301369863 0.514775740167919 0.903603568722262 0.999572226578691 GO:0004197 cysteine-type endopeptidase activity 1/496 88/18639 0.0113636363636364 0.427029875366569 0.907367124318825 0.999572226578691 GO:0141003 histone H2AX kinase activity 6/496 354/18639 0.0169491525423729 0.636925915800984 0.91258971236711 0.999572226578691 GO:0140996 histone H3 kinase activity 6/496 357/18639 0.0168067226890756 0.631573597180808 0.91643214457963 0.999572226578691 GO:0016410 N-acyltransferase activity 1/496 94/18639 0.0106382978723404 0.399772649279341 0.921270679787824 0.999572226578691 GO:0042578 phosphoric ester hydrolase activity 6/496 363/18639 0.0165289256198347 0.621134364169555 0.923678370532336 0.999572226578691 GO:0140658 ATP-dependent chromatin remodeler activity 2/496 158/18639 0.0126582278481013 0.475678848509596 0.925825452010447 0.999572226578691 GO:0016741 transferase activity, transferring one-carbon groups 3/496 215/18639 0.013953488372093 0.52435296324081 0.928169162237759 0.999572226578691 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 4/496 268/18639 0.0149253731343284 0.560875060182956 0.928921893253724 0.999572226578691 GO:0003689 DNA clamp loader activity 2/496 160/18639 0.0125 0.469732862903226 0.92902393051131 0.999572226578691 GO:0008170 N-methyltransferase activity 1/496 98/18639 0.0102040816326531 0.383455398288348 0.929362085486337 0.999572226578691 GO:0016887 ATP hydrolysis activity 7/496 417/18639 0.0167865707434053 0.630816314690183 0.930156065253861 0.999572226578691 GO:0016791 phosphatase activity 4/496 273/18639 0.0146520146520147 0.550602623183268 0.93494736608153 0.999572226578691 GO:0015081 sodium ion transmembrane transporter activity 2/496 164/18639 0.0121951219512195 0.458275963808025 0.935034259887657 0.999572226578691 GO:0016874 ligase activity 2/496 167/18639 0.0119760479041916 0.450043461464168 0.939222437977212 0.999572226578691 GO:0001217 DNA-binding transcription repressor activity 4/496 278/18639 0.0143884892086331 0.540699698305872 0.940506737213411 0.999572226578691 GO:0000149 SNARE binding 1/496 106/18639 0.00943396226415094 0.35451536822885 0.943139628039356 0.999572226578691 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/496 229/18639 0.0131004366812227 0.492296450204254 0.945404577551968 0.999572226578691 GO:0030695 GTPase regulator activity 8/496 489/18639 0.016359918200409 0.614783297051257 0.950723267538687 0.999572226578691 GO:0060589 nucleoside-triphosphatase regulator activity 8/496 490/18639 0.0163265306122449 0.613528637261356 0.951431964362572 0.999572226578691 GO:0022853 active monoatomic ion transmembrane transporter activity 1/496 118/18639 0.00847457627118644 0.318462957900492 0.958942726797283 0.999572226578691 GO:0008234 cysteine-type peptidase activity 2/496 187/18639 0.0106951871657754 0.401910470933241 0.961241248688091 0.999572226578691 GO:0106310 protein serine kinase activity 5/496 361/18639 0.0138504155124654 0.520479626485569 0.965393438484544 0.999572226578691 GO:0004519 endonuclease activity 1/496 127/18639 0.0078740157480315 0.295894716789434 0.967843820720282 0.999572226578691 GO:0019783 ubiquitin-like protein peptidase activity 1/496 127/18639 0.0078740157480315 0.295894716789434 0.967843820720282 0.999572226578691 GO:0031490 chromatin DNA binding 1/496 128/18639 0.0078125 0.293583039314516 0.968705395100291 0.999572226578691 GO:0008168 methyltransferase activity 2/496 204/18639 0.00980392156862745 0.368417931688805 0.973737652072192 0.999572226578691 GO:0008194 UDP-glycosyltransferase activity 1/496 145/18639 0.00689655172413793 0.259162958843159 0.980282305837033 0.999572226578691 GO:0004842 ubiquitin-protein transferase activity 6/496 449/18639 0.0133630289532294 0.502164307780731 0.981243139091308 0.999572226578691 GO:0000510 H3-H4 histone complex chaperone activity 1/496 151/18639 0.00662251655629139 0.248865092928861 0.983250309681508 0.999572226578691 GO:0140584 chromatin extrusion motor activity 1/496 151/18639 0.00662251655629139 0.248865092928861 0.983250309681508 0.999572226578691 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/496 151/18639 0.00662251655629139 0.248865092928861 0.983250309681508 0.999572226578691 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/496 151/18639 0.00662251655629139 0.248865092928861 0.983250309681508 0.999572226578691 GO:0015616 DNA translocase activity 1/496 152/18639 0.00657894736842105 0.247227822580645 0.983699673939295 0.999572226578691 GO:0140674 ATP-dependent histone chaperone activity 1/496 152/18639 0.00657894736842105 0.247227822580645 0.983699673939295 0.999572226578691 GO:0061775 cohesin loader activity 1/496 153/18639 0.0065359477124183 0.245611954459203 0.984137006212033 0.999572226578691 GO:0061630 ubiquitin protein ligase activity 4/496 353/18639 0.0113314447592068 0.425820159005757 0.985591334831855 0.999572226578691 GO:0005085 guanyl-nucleotide exchange factor activity 2/496 230/18639 0.00869565217391304 0.326770687237027 0.985666946039937 0.999572226578691 GO:0140713 histone chaperone activity 1/496 164/18639 0.00609756097560976 0.229137981904013 0.988239660029601 0.999572226578691 GO:0019787 ubiquitin-like protein transferase activity 6/496 479/18639 0.0125260960334029 0.470713516061688 0.988945836120069 0.999572226578691 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/496 167/18639 0.00598802395209581 0.225021730732084 0.989161699525998 0.999572226578691 GO:0061659 ubiquitin-like protein ligase activity 4/496 372/18639 0.010752688172043 0.404071279916753 0.990136808938091 0.999572226578691 GO:0042393 histone binding 2/496 247/18639 0.00809716599190283 0.304280397022333 0.990409282264108 0.999572226578691 GO:0004674 protein serine/threonine kinase activity 5/496 433/18639 0.0115473441108545 0.433933360649631 0.990733788532511 0.999572226578691 GO:0016755 aminoacyltransferase activity 6/496 496/18639 0.0120967741935484 0.454580189906348 0.991870649866374 0.999572226578691 GO:0140597 protein carrier chaperone 1/496 188/18639 0.00531914893617021 0.199886324639671 0.99388231963304 0.999572226578691 GO:0016758 hexosyltransferase activity 1/496 197/18639 0.0050761421319797 0.190754462092681 0.99521311633817 0.999572226578691 GO:0004518 nuclease activity 1/496 209/18639 0.00478468899521531 0.179802052785924 0.996549153461717 0.999572226578691 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/496 243/18639 0.00411522633744856 0.154644563918757 0.998636290686689 0.999572226578691 GO:0030371 translation repressor activity 2/496 329/18639 0.0060790273556231 0.228441513873909 0.998686706427629 0.999572226578691 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:0004711 ribosomal protein S6 kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:0035175 histone H3S10 kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:0035979 histone H2AXS139 kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:0044022 histone H3S28 kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:0044023 histone H4S1 kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:0044024 histone H2AS1 kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:0044025 histone H2BS14 kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:0072354 histone H3T3 kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:0072371 histone H2AS121 kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:0140823 histone H2BS36 kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:0140855 histone H3S57 kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:0140995 histone H2A kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:0140997 histone H4 kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:0140998 histone H2B kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:1990244 histone H2AT120 kinase activity 1/496 245/18639 0.00408163265306122 0.153382159315339 0.998708838961702 0.999572226578691 GO:0004677 DNA-dependent protein kinase activity 1/496 246/18639 0.0040650406504065 0.152758654602675 0.998743655525527 0.999572226578691 GO:0140857 histone H3T45 kinase activity 1/496 246/18639 0.0040650406504065 0.152758654602675 0.998743655525527 0.999572226578691 GO:0035402 histone H3T11 kinase activity 1/496 247/18639 0.00404858299595142 0.152140198511166 0.99877753509163 0.999572226578691 GO:0035403 histone H3T6 kinase activity 1/496 247/18639 0.00404858299595142 0.152140198511166 0.99877753509163 0.999572226578691 GO:0004679 AMP-activated protein kinase activity 1/496 248/18639 0.00403225806451613 0.151526729968783 0.998810502827306 0.999572226578691 GO:0016757 glycosyltransferase activity 1/496 267/18639 0.00374531835205993 0.140743928959768 0.999292620903766 0.999572226578691 GO:0005216 monoatomic ion channel activity 3/496 448/18639 0.00669642857142857 0.251642605126728 0.999551700153651 0.999572226578691 GO:0046873 metal ion transmembrane transporter activity 3/496 450/18639 0.00666666666666667 0.250524193548387 0.999572226578691 0.999572226578691