ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0043021 ribonucleoprotein complex binding 88/3206 177/18639 0.497175141242938 2.89047019888556 2.08377884944572e-23 2.70057738888165e-20 GO:0045296 cadherin binding 122/3206 334/18639 0.365269461077844 2.12359871647846 1.17398672958896e-17 7.60743400773643e-15 GO:0043022 ribosome binding 54/3206 112/18639 0.482142857142857 2.80307570626504 3.42027945540055e-14 1.47756072473304e-11 GO:0016887 ATP hydrolysis activity 131/3206 417/18639 0.314148681055156 1.82639340804337 5.13638419716628e-13 1.66418847988187e-10 GO:0003735 structural constituent of ribosome 69/3206 175/18639 0.394285714285714 2.2922930220123 2.2883489606696e-12 5.93140050605559e-10 GO:0140104 molecular carrier activity 86/3206 249/18639 0.345381526104418 2.00797450563326 2.38420582690218e-11 5.1498845861087e-09 GO:0042393 histone binding 85/3206 247/18639 0.34412955465587 2.00069581073948 3.85396095969685e-11 7.13533343395302e-09 GO:0016853 isomerase activity 64/3206 180/18639 0.355555555555556 2.06712414223331 2.20274522667217e-09 3.56844726720891e-07 GO:0016860 intramolecular oxidoreductase activity 28/3206 53/18639 0.528301886792453 3.07143445662025 3.61358484174719e-09 5.20356217211595e-07 GO:0140097 catalytic activity, acting on DNA 100/3206 336/18639 0.297619047619048 1.73029364584262 7.29524712862366e-09 9.45464027869626e-07 GO:0031625 ubiquitin protein ligase binding 92/3206 302/18639 0.304635761589404 1.77108732385056 8.25910215221197e-09 9.73072399024246e-07 GO:0051082 unfolded protein binding 47/3206 121/18639 0.388429752066116 2.25824770703691 1.22833296324287e-08 1.31341167342956e-06 GO:0044389 ubiquitin-like protein ligase binding 96/3206 322/18639 0.298136645962733 1.73330285218321 1.31746541316236e-08 1.31341167342956e-06 GO:0030515 snoRNA binding 19/3206 32/18639 0.59375 3.45193582345602 9.95500966136683e-08 9.21549465795101e-06 GO:0015631 tubulin binding 107/3206 385/18639 0.277922077922078 1.6157796663723 1.17612347690702e-07 1.01617068404767e-05 GO:0140597 protein carrier chaperone 61/3206 188/18639 0.324468085106383 1.88638822155267 2.35282734862525e-07 1.90579015238645e-05 GO:0140662 ATP-dependent protein folding chaperone 21/3206 40/18639 0.525 3.05223799126638 3.76277889478379e-07 2.83807969635985e-05 GO:0180051 translation factor activity 34/3206 84/18639 0.404761904761905 2.35319935834596 3.94177735605534e-07 2.83807969635985e-05 GO:0003713 transcription coactivator activity 76/3206 256/18639 0.296875 1.72596791172801 4.99197944392079e-07 3.40505545227439e-05 GO:0008094 ATP-dependent activity, acting on DNA 65/3206 210/18639 0.30952380952381 1.79950539167632 6.55200287633916e-07 4.11900480310209e-05 GO:0070182 DNA polymerase binding 14/3206 21/18639 0.666666666666667 3.87585776668746 6.67431333835986e-07 4.11900480310209e-05 GO:0008135 translation factor activity, RNA binding 33/3206 83/18639 0.397590361445783 2.31150553555457 9.44060134217329e-07 5.56137242702572e-05 GO:0031720 haptoglobin binding 9/3206 10/18639 0.9 5.23240798502807 1.10399800484174e-06 6.22078875771693e-05 GO:0004386 helicase activity 51/3206 155/18639 0.329032258064516 1.9129233493651 1.39067316231868e-06 7.5096350765209e-05 GO:0140517 protein-RNA adaptor activity 14/3206 22/18639 0.636363636363636 3.69968241365621 1.5436039829935e-06 8.00204304783832e-05 GO:0003727 single-stranded RNA binding 34/3206 89/18639 0.382022471910112 2.22099714720293 1.91858422727578e-06 9.56340445595928e-05 GO:0015035 protein-disulfide reductase activity 18/3206 34/18639 0.529411764705882 3.07788705001651 2.19498760828448e-06 0.000105359405197655 GO:0044183 protein folding chaperone 30/3206 75/18639 0.4 2.32551466001248 2.5068746096557e-06 0.000116032481932635 GO:0003743 translation initiation factor activity 23/3206 51/18639 0.450980392156863 2.6219037833474 3.29406301964984e-06 0.000147210540464352 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 22/3206 48/18639 0.458333333333333 2.66465221459763 3.859621734186e-06 0.000166735658916835 GO:0003712 transcription coregulator activity 124/3206 495/18639 0.250505050505051 1.45638291839165 4.96352089807477e-06 0.000207507196254997 GO:0140098 catalytic activity, acting on RNA 101/3206 387/18639 0.260981912144703 1.51729315672649 5.82656222073836e-06 0.000235975769939904 GO:0017070 U6 snRNA binding 11/3206 16/18639 0.6875 3.99697832189644 7.15586332271998e-06 0.000281030268674094 GO:0015036 disulfide oxidoreductase activity 19/3206 40/18639 0.475 2.76154865876482 9.21650068297572e-06 0.000351311320151075 GO:0003756 protein disulfide isomerase activity 12/3206 19/18639 0.631578947368421 3.67186525265128 9.98810691748103e-06 0.000359571849029317 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 12/3206 19/18639 0.631578947368421 3.67186525265128 9.98810691748103e-06 0.000359571849029317 GO:0017069 snRNA binding 23/3206 54/18639 0.425925925925926 2.47624246205032 1.06937439979944e-05 0.000374570060037858 GO:0017056 structural constituent of nuclear pore 14/3206 25/18639 0.56 3.25572052401747 1.28126671693799e-05 0.000436979385566221 GO:0003697 single-stranded DNA binding 40/3206 121/18639 0.330578512396694 1.92191294215907 1.6138357873489e-05 0.00053629004625748 GO:0003689 DNA clamp loader activity 49/3206 160/18639 0.30625 1.78047216157205 2.03317449340008e-05 0.000648516399129871 GO:0008017 microtubule binding 75/3206 276/18639 0.271739130434783 1.57983332881282 2.05163367008678e-05 0.000648516399129871 GO:0140297 DNA-binding transcription factor binding 119/3206 488/18639 0.243852459016393 1.41770617080679 2.84859898338833e-05 0.000878996257731257 GO:0004601 peroxidase activity 23/3206 57/18639 0.403508771929825 2.34591391141609 3.07889396321321e-05 0.000927964320075422 GO:0008187 poly-pyrimidine tract binding 15/3206 30/18639 0.5 2.9068933250156 3.78442996665285e-05 0.0011146866447232 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 23/3206 59/18639 0.389830508474576 2.26639140594436 5.8773094811308e-05 0.00169266513056567 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 49/3206 167/18639 0.293413173652695 1.70584159192532 6.91749534951443e-05 0.00194459514012824 GO:0046915 transition metal ion transmembrane transporter activity 19/3206 45/18639 0.422222222222222 2.45470991890206 7.13467621458699e-05 0.00194459514012824 GO:0003725 double-stranded RNA binding 27/3206 75/18639 0.36 2.09296319401123 7.2022042226972e-05 0.00194459514012824 GO:0070990 snRNP binding 8/3206 11/18639 0.727272727272727 4.22820847274996 7.6469773309165e-05 0.00202254747364649 GO:0140713 histone chaperone activity 48/3206 164/18639 0.292682926829268 1.70159609269206 8.72845151488528e-05 0.00226241463265827 GO:0016741 transferase activity, transferring one-carbon groups 59/3206 215/18639 0.274418604651163 1.59541122024112 0.000110985631398534 0.00277200866796141 GO:0019843 rRNA binding 24/3206 65/18639 0.369230769230769 2.14662891693459 0.000112918702717245 0.00277200866796141 GO:0005344 oxygen carrier activity 9/3206 14/18639 0.642857142857143 3.73743427502005 0.000113361465587928 0.00277200866796141 GO:0061775 cohesin loader activity 45/3206 153/18639 0.294117647058824 1.70993725000917 0.000125923636383168 0.00302216727319604 GO:0000287 magnesium ion binding 62/3206 230/18639 0.269565217391304 1.56719466218232 0.000131091248009699 0.00304786877325684 GO:0032977 membrane insertase activity 10/3206 17/18639 0.588235294117647 3.41987450001835 0.000133777216439759 0.00304786877325684 GO:0017116 single-stranded DNA helicase activity 22/3206 58/18639 0.379310344827586 2.20522941897735 0.000136145577132178 0.00304786877325684 GO:0019838 growth factor binding 41/3206 136/18639 0.301470588235294 1.7526856812594 0.00013640153460563 0.00304786877325684 GO:0043024 ribosomal small subunit binding 11/3206 20/18639 0.55 3.19758265751716 0.000139725621160959 0.00306922720380684 GO:0003678 DNA helicase activity 26/3206 74/18639 0.351351351351351 2.04268179595691 0.000154231130910032 0.00333139242765669 GO:1990247 N6-methyladenosine-containing RNA reader activity 8/3206 12/18639 0.666666666666667 3.87585776668746 0.000194644760242296 0.00413540343072157 GO:0048027 mRNA 5'-UTR binding 12/3206 24/18639 0.5 2.9068933250156 0.000228752394638508 0.00472286540167956 GO:0140101 catalytic activity, acting on a tRNA 41/3206 139/18639 0.294964028776978 1.71485793274301 0.000229583734803868 0.00472286540167956 GO:0030145 manganese ion binding 24/3206 68/18639 0.352941176470588 2.05192470001101 0.000251944077856468 0.00510186757659348 GO:0140658 ATP-dependent chromatin remodeler activity 45/3206 158/18639 0.284810126582278 1.65582531171774 0.000281638891725423 0.00561544621040228 GO:0035198 miRNA binding 17/3206 42/18639 0.404761904761905 2.35319935834596 0.000313000387765011 0.00614618943247658 GO:0001094 TFIID-class transcription factor complex binding 7/3206 10/18639 0.7 4.06965065502183 0.00032670293214748 0.0062265735303402 GO:0016427 tRNA (cytidine) methyltransferase activity 7/3206 10/18639 0.7 4.06965065502183 0.00032670293214748 0.0062265735303402 GO:0000510 H3-H4 histone complex chaperone activity 43/3206 151/18639 0.28476821192053 1.65558162881683 0.000381088977725556 0.00670661194471683 GO:0140584 chromatin extrusion motor activity 43/3206 151/18639 0.28476821192053 1.65558162881683 0.000381088977725556 0.00670661194471683 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 43/3206 151/18639 0.28476821192053 1.65558162881683 0.000381088977725556 0.00670661194471683 GO:0140849 ATP-dependent H2AZ histone chaperone activity 43/3206 151/18639 0.28476821192053 1.65558162881683 0.000381088977725556 0.00670661194471683 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 20/3206 54/18639 0.37037037037037 2.15325431482637 0.000391404006352493 0.00670661194471683 GO:0022884 macromolecule transmembrane transporter activity 14/3206 32/18639 0.4375 2.54353165938865 0.000407035053349557 0.00670661194471683 GO:0031369 translation initiation factor binding 14/3206 32/18639 0.4375 2.54353165938865 0.000407035053349557 0.00670661194471683 GO:0051059 NF-kappaB binding 14/3206 32/18639 0.4375 2.54353165938865 0.000407035053349557 0.00670661194471683 GO:0070717 poly-purine tract binding 14/3206 32/18639 0.4375 2.54353165938865 0.000407035053349557 0.00670661194471683 GO:0031491 nucleosome binding 25/3206 74/18639 0.337837837837838 1.96411711149702 0.000408813536753572 0.00670661194471683 GO:0035064 methylated histone binding 25/3206 74/18639 0.337837837837838 1.96411711149702 0.000408813536753572 0.00670661194471683 GO:0051087 protein-folding chaperone binding 39/3206 134/18639 0.291044776119403 1.6920722339643 0.0004332043658373 0.00701791072656425 GO:0015616 DNA translocase activity 43/3206 152/18639 0.282894736842105 1.64468964441672 0.000444356382805539 0.00702299844043877 GO:0140674 ATP-dependent histone chaperone activity 43/3206 152/18639 0.282894736842105 1.64468964441672 0.000444356382805539 0.00702299844043877 GO:0043023 ribosomal large subunit binding 9/3206 16/18639 0.5625 3.27025499064255 0.000464921240393639 0.0071975846263024 GO:0019208 phosphatase regulator activity 35/3206 117/18639 0.299145299145299 1.73916694659053 0.000476749494719252 0.0071975846263024 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 15/3206 36/18639 0.416666666666667 2.42241110417966 0.000483171190191597 0.0071975846263024 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 15/3206 36/18639 0.416666666666667 2.42241110417966 0.000483171190191597 0.0071975846263024 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 15/3206 36/18639 0.416666666666667 2.42241110417966 0.000483171190191597 0.0071975846263024 GO:0005048 signal sequence binding 19/3206 51/18639 0.372549019607843 2.16592051667829 0.000498349146831264 0.0073393237987877 GO:0070063 RNA polymerase binding 21/3206 59/18639 0.355932203389831 2.06931389238398 0.000527433178253321 0.00768037526984611 GO:0070006 metalloaminopeptidase activity 12/3206 26/18639 0.461538461538462 2.68328614616824 0.000582177101857672 0.00838335026675047 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 14/3206 33/18639 0.424242424242424 2.46645494243748 0.000595855067820276 0.00846090282619371 GO:0051117 ATPase binding 27/3206 84/18639 0.321428571428571 1.86871713751003 0.000600619645069307 0.00846090282619371 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 84/3206 349/18639 0.240687679083095 1.39930681548029 0.000619625256395582 0.00863477776654488 GO:0140034 methylation-dependent protein binding 25/3206 76/18639 0.328947368421053 1.91242981908921 0.000642832679444892 0.00886288460170829 GO:0051219 phosphoprotein binding 29/3206 93/18639 0.311827956989247 1.81290121345059 0.000671743163569404 0.00907771840244353 GO:1990841 promoter-specific chromatin binding 23/3206 68/18639 0.338235294117647 1.96642783751055 0.000672423585366187 0.00907771840244353 GO:0140318 protein transporter activity 16/3206 41/18639 0.390243902439024 2.26879479025608 0.000754757500736507 0.0100841826902527 GO:0004659 prenyltransferase activity 9/3206 17/18639 0.529411764705882 3.07788705001651 0.000837458267341757 0.0110280917948023 GO:0019887 protein kinase regulator activity 64/3206 255/18639 0.250980392156863 1.45914645334116 0.000850450370623854 0.0110280917948023 GO:0140296 general transcription initiation factor binding 19/3206 53/18639 0.358490566037736 2.08418766699231 0.000864907461864562 0.0110280917948023 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 21/3206 61/18639 0.344262295081967 2.00146753525664 0.000872946029119256 0.0110280917948023 GO:0005385 zinc ion transmembrane transporter activity 12/3206 27/18639 0.444444444444444 2.58390517779164 0.000884970329212533 0.0110280917948023 GO:0008266 poly(U) RNA binding 12/3206 27/18639 0.444444444444444 2.58390517779164 0.000884970329212533 0.0110280917948023 GO:0008320 protein transmembrane transporter activity 12/3206 27/18639 0.444444444444444 2.58390517779164 0.000884970329212533 0.0110280917948023 GO:0043531 ADP binding 15/3206 38/18639 0.394736842105263 2.29491578290705 0.000952773212246063 0.0117599436482943 GO:0008168 methyltransferase activity 53/3206 204/18639 0.259803921568627 1.51044457084144 0.000988884706117027 0.0120905148974308 GO:0016859 cis-trans isomerase activity 16/3206 42/18639 0.380952380952381 2.21477586667855 0.00102660803179589 0.0124344299925932 GO:0140033 acetylation-dependent protein binding 11/3206 24/18639 0.458333333333333 2.66465221459763 0.00105929091130659 0.0127114909356791 GO:0031072 heat shock protein binding 37/3206 131/18639 0.282442748091603 1.64206187825308 0.00110619058402041 0.0131525045586279 GO:0061980 regulatory RNA binding 20/3206 58/18639 0.344827586206897 2.00475401725213 0.00112128155383124 0.0132107353978663 GO:0000217 DNA secondary structure binding 15/3206 39/18639 0.384615384615385 2.23607178847354 0.00130469617016426 0.0150971985404722 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 15/3206 39/18639 0.384615384615385 2.23607178847354 0.00130469617016426 0.0150971985404722 GO:0008173 RNA methyltransferase activity 22/3206 67/18639 0.328358208955224 1.90900457165203 0.00135976557664551 0.0155951874985185 GO:0140142 nucleocytoplasmic carrier activity 13/3206 32/18639 0.40625 2.36185082657517 0.00150737141703784 0.017136432951588 GO:0016423 tRNA (guanine) methyltransferase activity 7/3206 12/18639 0.583333333333333 3.39137554585153 0.00156256363993566 0.0174576075634191 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 7/3206 12/18639 0.583333333333333 3.39137554585153 0.00156256363993566 0.0174576075634191 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 22/3206 68/18639 0.323529411764706 1.88093097501009 0.00168849435508346 0.0187033220870783 GO:0019888 protein phosphatase regulator activity 31/3206 107/18639 0.289719626168224 1.68436809486885 0.00172869459082288 0.0189863405907326 GO:0004177 aminopeptidase activity 15/3206 40/18639 0.375 2.1801699937617 0.00175951004862426 0.0191623951514037 GO:0001098 basal transcription machinery binding 20/3206 60/18639 0.333333333333333 1.93792888334373 0.00179798694731654 0.0192577775514234 GO:0001099 basal RNA polymerase II transcription machinery binding 20/3206 60/18639 0.333333333333333 1.93792888334373 0.00179798694731654 0.0192577775514234 GO:0019207 kinase regulator activity 69/3206 287/18639 0.240418118466899 1.39773964756847 0.00185352830830561 0.0196899400620005 GO:0070034 telomerase RNA binding 10/3206 22/18639 0.454545454545455 2.64263029546872 0.00193187345370804 0.0203553495610213 GO:0016209 antioxidant activity 26/3206 86/18639 0.302325581395349 1.7576564290792 0.00203831942973623 0.021303725652727 GO:0061650 ubiquitin-like protein conjugating enzyme activity 15/3206 41/18639 0.365853658536585 2.12699511586507 0.00233917498009796 0.0242525661936557 GO:0060590 ATPase regulator activity 17/3206 49/18639 0.346938775510204 2.01702802143939 0.00238836175976043 0.0245660066718216 GO:0048029 monosaccharide binding 23/3206 74/18639 0.310810810810811 1.80698774257726 0.00242385676786074 0.0247347903239962 GO:0003688 DNA replication origin binding 8/3206 16/18639 0.5 2.9068933250156 0.00263432619750895 0.0266725527497782 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 35/3206 128/18639 0.2734375 1.5897072871179 0.00270116018245498 0.0271372371818733 GO:0008175 tRNA methyltransferase activity 13/3206 34/18639 0.382352941176471 2.22291842501193 0.00287112737661785 0.0273948750626638 GO:0005522 profilin binding 6/3206 10/18639 0.6 3.48827199001871 0.00287601188620942 0.0273948750626638 GO:0008641 ubiquitin-like modifier activating enzyme activity 6/3206 10/18639 0.6 3.48827199001871 0.00287601188620942 0.0273948750626638 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 6/3206 10/18639 0.6 3.48827199001871 0.00287601188620942 0.0273948750626638 GO:0047429 nucleoside triphosphate diphosphatase activity 6/3206 10/18639 0.6 3.48827199001871 0.00287601188620942 0.0273948750626638 GO:0097177 mitochondrial ribosome binding 6/3206 10/18639 0.6 3.48827199001871 0.00287601188620942 0.0273948750626638 GO:0031994 insulin-like growth factor I binding 7/3206 13/18639 0.538461538461538 3.13050050386295 0.00288438829707641 0.0273948750626638 GO:0070577 lysine-acetylated histone binding 10/3206 23/18639 0.434782608695652 2.52773332610052 0.00289590886079085 0.0273948750626638 GO:0009055 electron transfer activity 32/3206 116/18639 0.275862068965517 1.60380321380171 0.00345446864758962 0.0324419664295373 GO:0000339 RNA cap binding 9/3206 20/18639 0.45 2.61620399251404 0.00353271928945725 0.0329381597060186 GO:0001618 virus receptor activity 24/3206 81/18639 0.296296296296296 1.72260345186109 0.00396329966269278 0.0365315926548683 GO:0048156 tau protein binding 15/3206 43/18639 0.348837209302326 2.028065110476 0.00397450197865465 0.0365315926548683 GO:0003779 actin binding 98/3206 443/18639 0.221218961625282 1.28611984583083 0.00414641194816306 0.0378433090480234 GO:0005092 GDP-dissociation inhibitor activity 8/3206 17/18639 0.470588235294118 2.73589960001468 0.00423154213543536 0.0378917711091194 GO:0051787 misfolded protein binding 8/3206 17/18639 0.470588235294118 2.73589960001468 0.00423154213543536 0.0378917711091194 GO:0051540 metal cluster binding 23/3206 77/18639 0.298701298701299 1.73658562273659 0.00423943426760981 0.0378917711091194 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 19/3206 60/18639 0.316666666666667 1.84103243917654 0.00442854174985848 0.0393108911494287 GO:0140272 exogenous protein binding 24/3206 82/18639 0.292682926829268 1.70159609269206 0.00470730740662143 0.041501159176744 GO:0003714 transcription corepressor activity 50/3206 204/18639 0.245098039215686 1.42494770834098 0.00487266949955982 0.042668781563713 GO:1990825 sequence-specific mRNA binding 7/3206 14/18639 0.5 2.9068933250156 0.00491759270270169 0.0427731553201436 GO:0055106 ubiquitin-protein transferase regulator activity 13/3206 36/18639 0.361111111111111 2.09942295695571 0.00510320288834276 0.0438896058321624 GO:0019001 guanyl nucleotide binding 89/3206 400/18639 0.2225 1.29356752963194 0.00515892400477684 0.0438896058321624 GO:0032561 guanyl ribonucleotide binding 89/3206 400/18639 0.2225 1.29356752963194 0.00515892400477684 0.0438896058321624 GO:0015399 primary active transmembrane transporter activity 42/3206 166/18639 0.253012048192771 1.47095806808018 0.00519175366312368 0.0438896058321624 GO:0035613 RNA stem-loop binding 9/3206 21/18639 0.428571428571429 2.49162285001337 0.00524914267282806 0.0438896058321624 GO:0072542 protein phosphatase activator activity 9/3206 21/18639 0.428571428571429 2.49162285001337 0.00524914267282806 0.0438896058321624 GO:0005536 D-glucose binding 6/3206 11/18639 0.545454545454545 3.17115635456247 0.00540969299752329 0.0443731780050012 GO:0048185 activin binding 6/3206 11/18639 0.545454545454545 3.17115635456247 0.00540969299752329 0.0443731780050012 GO:0048407 platelet-derived growth factor binding 6/3206 11/18639 0.545454545454545 3.17115635456247 0.00540969299752329 0.0443731780050012 GO:0016874 ligase activity 42/3206 167/18639 0.251497005988024 1.46214993593599 0.00580766063673601 0.0473379131145275 GO:0008139 nuclear localization sequence binding 10/3206 25/18639 0.4 2.32551466001248 0.00594639589469613 0.0481658067470387 GO:0035250 UDP-galactosyltransferase activity 11/3206 29/18639 0.379310344827586 2.20522941897735 0.0063751869827491 0.0510014958619928 GO:0106222 lncRNA binding 11/3206 29/18639 0.379310344827586 2.20522941897735 0.0063751869827491 0.0510014958619928 GO:0000400 four-way junction DNA binding 8/3206 18/18639 0.444444444444444 2.58390517779164 0.00648051000490053 0.0515260181984729 GO:0140030 modification-dependent protein binding 43/3206 173/18639 0.248554913294798 1.44504523671296 0.00661133689686662 0.0522456866971899 GO:0140463 chromatin-protein adaptor activity 17/3206 54/18639 0.314814814814815 1.83026616760241 0.00735843348922717 0.0577971503153843 GO:0019842 vitamin binding 38/3206 150/18639 0.253333333333333 1.47282595134124 0.00740378772050494 0.0578030655769542 GO:0051536 iron-sulfur cluster binding 22/3206 76/18639 0.289473684210526 1.6829382407985 0.0076266023381417 0.0591860876061775 GO:0000774 adenyl-nucleotide exchange factor activity 7/3206 15/18639 0.466666666666667 2.71310043668122 0.00786456556348329 0.0603105146170079 GO:0055105 ubiquitin-protein transferase inhibitor activity 7/3206 15/18639 0.466666666666667 2.71310043668122 0.00786456556348329 0.0603105146170079 GO:0051015 actin filament binding 50/3206 209/18639 0.239234449760766 1.3908580502467 0.00795974009773013 0.0606813127450485 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 54/3206 229/18639 0.235807860262009 1.37093658996369 0.00812045491374012 0.0615445003988725 GO:0008143 poly(A) binding 10/3206 26/18639 0.384615384615385 2.23607178847354 0.00819655017919593 0.0617600525130112 GO:0015101 organic cation transmembrane transporter activity 23/3206 81/18639 0.283950617283951 1.65082830803355 0.00830112426584331 0.0621749897238053 GO:0031492 nucleosomal DNA binding 14/3206 42/18639 0.333333333333333 1.93792888334373 0.00834756806477016 0.0621749897238053 GO:0022853 active monoatomic ion transmembrane transporter activity 31/3206 118/18639 0.26271186440678 1.52735073009294 0.00851718879220556 0.0627810398302756 GO:0035925 mRNA 3'-UTR AU-rich region binding 11/3206 30/18639 0.366666666666667 2.1317217716781 0.00852810147539199 0.0627810398302756 GO:0016922 nuclear receptor binding 35/3206 137/18639 0.255474452554745 1.4852739616868 0.00861757173960767 0.0627810398302756 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 12/3206 34/18639 0.352941176470588 2.05192470001101 0.00862270454459033 0.0627810398302756 GO:0031490 chromatin DNA binding 33/3206 128/18639 0.2578125 1.49886687071117 0.00914448431744062 0.0659167130341965 GO:0017166 vinculin binding 6/3206 12/18639 0.5 2.9068933250156 0.00925682235511092 0.0659167130341965 GO:0035251 UDP-glucosyltransferase activity 6/3206 12/18639 0.5 2.9068933250156 0.00925682235511092 0.0659167130341965 GO:0035259 nuclear glucocorticoid receptor binding 6/3206 12/18639 0.5 2.9068933250156 0.00925682235511092 0.0659167130341965 GO:0005525 GTP binding 83/3206 378/18639 0.21957671957672 1.27657220093277 0.00948471372529148 0.0667517621834327 GO:0005520 insulin-like growth factor binding 8/3206 19/18639 0.421052631578947 2.44791016843419 0.00952860802772766 0.0667517621834327 GO:0046527 glucosyltransferase activity 8/3206 19/18639 0.421052631578947 2.44791016843419 0.00952860802772766 0.0667517621834327 GO:0043539 protein serine/threonine kinase activator activity 21/3206 73/18639 0.287671232876712 1.67245917329664 0.00970840129831198 0.0676456348527545 GO:0016758 hexosyltransferase activity 47/3206 197/18639 0.238578680203046 1.38704554594653 0.0103566247178704 0.0717763937666309 GO:0017134 fibroblast growth factor binding 9/3206 23/18639 0.391304347826087 2.27495999349047 0.0105348739056094 0.0726233860727116 GO:0001671 ATPase activator activity 10/3206 27/18639 0.37037037037037 2.15325431482637 0.0110470447535366 0.0757511640242511 GO:0003684 damaged DNA binding 21/3206 74/18639 0.283783783783784 1.6498583736575 0.0114097240728061 0.0778263284124035 GO:0005521 lamin binding 7/3206 16/18639 0.4375 2.54353165938865 0.0119325295147967 0.0809662735663689 GO:0030020 extracellular matrix structural constituent conferring tensile strength 14/3206 44/18639 0.318181818181818 1.84984120682811 0.0129652584918306 0.0875154948198564 GO:0004860 protein kinase inhibitor activity 23/3206 84/18639 0.273809523809524 1.59187015417521 0.013076477717435 0.0878088866414286 GO:0015095 magnesium ion transmembrane transporter activity 8/3206 20/18639 0.4 2.32551466001248 0.0135258671865746 0.0893889225795973 GO:0061608 nuclear import signal receptor activity 8/3206 20/18639 0.4 2.32551466001248 0.0135258671865746 0.0893889225795973 GO:0004532 RNA exonuclease activity 13/3206 40/18639 0.325 1.88948066126014 0.0135876680155715 0.0893889225795973 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 13/3206 40/18639 0.325 1.88948066126014 0.0135876680155715 0.0893889225795973 GO:0000993 RNA polymerase II complex binding 12/3206 36/18639 0.333333333333333 1.93792888334373 0.0141109435146143 0.0912713189616148 GO:0000049 tRNA binding 22/3206 80/18639 0.275 1.59879132875858 0.0142489312998137 0.0912713189616148 GO:0001091 RNA polymerase II general transcription initiation factor binding 9/3206 24/18639 0.375 2.1801699937617 0.0143311309541501 0.0912713189616148 GO:0070300 phosphatidic acid binding 9/3206 24/18639 0.375 2.1801699937617 0.0143311309541501 0.0912713189616148 GO:0070840 dynein complex binding 9/3206 24/18639 0.375 2.1801699937617 0.0143311309541501 0.0912713189616148 GO:0015179 L-amino acid transmembrane transporter activity 18/3206 62/18639 0.290322580645161 1.68787354355744 0.0144546502808045 0.0912713189616148 GO:0008378 galactosyltransferase activity 11/3206 32/18639 0.34375 1.99848916094822 0.0144737152200787 0.0912713189616148 GO:0016866 intramolecular transferase activity 10/3206 28/18639 0.357142857142857 2.07635237501114 0.0145885683155962 0.0912713189616148 GO:0009982 pseudouridine synthase activity 6/3206 13/18639 0.461538461538462 2.68328614616824 0.0147189086905691 0.0912713189616148 GO:0019104 DNA N-glycosylase activity 6/3206 13/18639 0.461538461538462 2.68328614616824 0.0147189086905691 0.0912713189616148 GO:0043560 insulin receptor substrate binding 6/3206 13/18639 0.461538461538462 2.68328614616824 0.0147189086905691 0.0912713189616148 GO:0140852 histone ubiquitin ligase activity 6/3206 13/18639 0.461538461538462 2.68328614616824 0.0147189086905691 0.0912713189616148 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 17/3206 58/18639 0.293103448275862 1.70404091466431 0.015599279125535 0.0962698368890158 GO:0019210 kinase inhibitor activity 24/3206 90/18639 0.266666666666667 1.55034310667498 0.0158472252532087 0.097274823843842 GO:0004715 non-membrane spanning protein tyrosine kinase activity 14/3206 45/18639 0.311111111111111 1.80873362445415 0.0159122397028507 0.097274823843842 GO:0015175 neutral L-amino acid transmembrane transporter activity 13/3206 41/18639 0.317073170731707 1.84339576708306 0.0168375889441407 0.102448428505194 GO:0016018 cyclosporin A binding 7/3206 17/18639 0.411764705882353 2.39391215001284 0.0173232206803496 0.103336277935865 GO:0070402 NADPH binding 7/3206 17/18639 0.411764705882353 2.39391215001284 0.0173232206803496 0.103336277935865 GO:0008190 eukaryotic initiation factor 4E binding 5/3206 10/18639 0.5 2.9068933250156 0.0176213869011004 0.103336277935865 GO:0015658 branched-chain amino acid transmembrane transporter activity 5/3206 10/18639 0.5 2.9068933250156 0.0176213869011004 0.103336277935865 GO:0015924 mannosyl-oligosaccharide mannosidase activity 5/3206 10/18639 0.5 2.9068933250156 0.0176213869011004 0.103336277935865 GO:0030957 Tat protein binding 5/3206 10/18639 0.5 2.9068933250156 0.0176213869011004 0.103336277935865 GO:0033204 ribonuclease P RNA binding 5/3206 10/18639 0.5 2.9068933250156 0.0176213869011004 0.103336277935865 GO:0050815 phosphoserine residue binding 5/3206 10/18639 0.5 2.9068933250156 0.0176213869011004 0.103336277935865 GO:0003724 RNA helicase activity 21/3206 77/18639 0.272727272727273 1.58557817728123 0.0179762352880975 0.104942346546731 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 8/3206 21/18639 0.380952380952381 2.21477586667855 0.018619236118111 0.107804886037515 GO:0001221 transcription coregulator binding 29/3206 115/18639 0.252173913043478 1.4660853291383 0.0187161260481798 0.107804886037515 GO:0017124 SH3 domain binding 29/3206 115/18639 0.252173913043478 1.4660853291383 0.0187161260481798 0.107804886037515 GO:0016407 acetyltransferase activity 25/3206 96/18639 0.260416666666667 1.51400694011229 0.0188122666394401 0.107879192764223 GO:0019211 phosphatase activator activity 9/3206 25/18639 0.36 2.09296319401123 0.019047544425093 0.108707826114783 GO:0032182 ubiquitin-like protein binding 30/3206 120/18639 0.25 1.4534466625078 0.0191245249646378 0.108707826114783 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 14/3206 46/18639 0.304347826086957 1.76941332827036 0.0193450056615369 0.109480905403283 GO:0043175 RNA polymerase core enzyme binding 13/3206 42/18639 0.30952380952381 1.79950539167632 0.020643460372824 0.116321411492087 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 17/3206 60/18639 0.283333333333333 1.64723955084217 0.0217817119606774 0.121889507916387 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 12/3206 38/18639 0.315789473684211 1.83593262632564 0.0219137772720048 0.121889507916387 GO:0042162 telomeric DNA binding 12/3206 38/18639 0.315789473684211 1.83593262632564 0.0219137772720048 0.121889507916387 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 6/3206 14/18639 0.428571428571429 2.49162285001337 0.0220698956814696 0.122233268389678 GO:0044325 transmembrane transporter binding 33/3206 136/18639 0.242647058823529 1.41069823125757 0.0222579654523045 0.122750311600794 GO:0016757 glycosyltransferase activity 59/3206 267/18639 0.220973782771536 1.28469442828405 0.0224771090101444 0.123433615581132 GO:0016651 oxidoreductase activity, acting on NAD(P)H 23/3206 88/18639 0.261363636363636 1.51951241989452 0.0225932443365872 0.123547867764629 GO:1990518 single-stranded 3'-5' DNA helicase activity 14/3206 47/18639 0.297872340425532 1.7317662361795 0.0233085848390498 0.126924058619363 GO:0008186 ATP-dependent activity, acting on RNA 21/3206 79/18639 0.265822784810127 1.54543695760323 0.0237798485539583 0.127614525227915 GO:0001968 fibronectin binding 10/3206 30/18639 0.333333333333333 1.93792888334373 0.0241030501563672 0.127614525227915 GO:0042826 histone deacetylase binding 31/3206 127/18639 0.244094488188976 1.41911327677927 0.0241185256577425 0.127614525227915 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 7/3206 18/18639 0.388888888888889 2.26091703056769 0.0242231274738171 0.127614525227915 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 7/3206 18/18639 0.388888888888889 2.26091703056769 0.0242231274738171 0.127614525227915 GO:0070064 proline-rich region binding 7/3206 18/18639 0.388888888888889 2.26091703056769 0.0242231274738171 0.127614525227915 GO:0070628 proteasome binding 7/3206 18/18639 0.388888888888889 2.26091703056769 0.0242231274738171 0.127614525227915 GO:1901611 phosphatidylglycerol binding 7/3206 18/18639 0.388888888888889 2.26091703056769 0.0242231274738171 0.127614525227915 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 13/3206 43/18639 0.302325581395349 1.7576564290792 0.0250568550538163 0.131472405464558 GO:0005080 protein kinase C binding 15/3206 52/18639 0.288461538461538 1.67705384135515 0.0256908099387723 0.134255200325197 GO:0008235 metalloexopeptidase activity 18/3206 66/18639 0.272727272727273 1.58557817728123 0.0271203847340181 0.141156701266215 GO:0003774 cytoskeletal motor activity 36/3206 153/18639 0.235294117647059 1.36794980000734 0.0275100481934423 0.142085313309577 GO:0008526 phosphatidylinositol transfer activity 5/3206 11/18639 0.454545454545455 2.64263029546872 0.0277977984874147 0.142085313309577 GO:0015173 aromatic amino acid transmembrane transporter activity 5/3206 11/18639 0.454545454545455 2.64263029546872 0.0277977984874147 0.142085313309577 GO:0034511 U3 snoRNA binding 5/3206 11/18639 0.454545454545455 2.64263029546872 0.0277977984874147 0.142085313309577 GO:0043138 3'-5' DNA helicase activity 14/3206 48/18639 0.291666666666667 1.69568777292576 0.0278469672690067 0.142085313309577 GO:0000175 3'-5'-RNA exonuclease activity 11/3206 35/18639 0.314285714285714 1.8271900900098 0.0285919320707144 0.143070053913691 GO:0034061 DNA polymerase activity 11/3206 35/18639 0.314285714285714 1.8271900900098 0.0285919320707144 0.143070053913691 GO:0043015 gamma-tubulin binding 11/3206 35/18639 0.314285714285714 1.8271900900098 0.0285919320707144 0.143070053913691 GO:0061631 ubiquitin conjugating enzyme activity 11/3206 35/18639 0.314285714285714 1.8271900900098 0.0285919320707144 0.143070053913691 GO:0140566 histone reader activity 11/3206 35/18639 0.314285714285714 1.8271900900098 0.0285919320707144 0.143070053913691 GO:0001046 core promoter sequence-specific DNA binding 13/3206 44/18639 0.295454545454545 1.71770969205467 0.0301275245798104 0.149027755173413 GO:0019205 nucleobase-containing compound kinase activity 13/3206 44/18639 0.295454545454545 1.71770969205467 0.0301275245798104 0.149027755173413 GO:0043014 alpha-tubulin binding 13/3206 44/18639 0.295454545454545 1.71770969205467 0.0301275245798104 0.149027755173413 GO:0004559 alpha-mannosidase activity 6/3206 15/18639 0.4 2.32551466001248 0.0315401157601271 0.154833295549715 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 6/3206 15/18639 0.4 2.32551466001248 0.0315401157601271 0.154833295549715 GO:0003887 DNA-directed DNA polymerase activity 8/3206 23/18639 0.347826086956522 2.02218666088041 0.0326334108710986 0.157809330182626 GO:0004602 glutathione peroxidase activity 8/3206 23/18639 0.347826086956522 2.02218666088041 0.0326334108710986 0.157809330182626 GO:0042171 lysophosphatidic acid acyltransferase activity 8/3206 23/18639 0.347826086956522 2.02218666088041 0.0326334108710986 0.157809330182626 GO:0071617 lysophospholipid acyltransferase activity 8/3206 23/18639 0.347826086956522 2.02218666088041 0.0326334108710986 0.157809330182626 GO:0051020 GTPase binding 67/3206 315/18639 0.212698412698413 1.23658319222886 0.034354231450871 0.165513323272598 GO:0004540 RNA nuclease activity 29/3206 121/18639 0.239669421487603 1.39338688306533 0.0355663570944525 0.170718514053372 GO:0005548 phospholipid transporter activity 18/3206 68/18639 0.264705882352941 1.53894352500826 0.0359463432730519 0.171905759711717 GO:0036002 pre-mRNA binding 16/3206 59/18639 0.271186440677966 1.57662010848303 0.0376485497796082 0.178727181371327 GO:0045309 protein phosphorylated amino acid binding 16/3206 59/18639 0.271186440677966 1.57662010848303 0.0376485497796082 0.178727181371327 GO:0008137 NADH dehydrogenase (ubiquinone) activity 12/3206 41/18639 0.292682926829268 1.70159609269206 0.0389983894546769 0.183122872221961 GO:0016877 ligase activity, forming carbon-sulfur bonds 12/3206 41/18639 0.292682926829268 1.70159609269206 0.0389983894546769 0.183122872221961 GO:0042169 SH2 domain binding 12/3206 41/18639 0.292682926829268 1.70159609269206 0.0389983894546769 0.183122872221961 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 29/3206 122/18639 0.237704918032787 1.38196567910578 0.0392359956177627 0.183573466861446 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 31/3206 132/18639 0.234848484848485 1.36535898599217 0.039459407615776 0.183954648453402 GO:0051537 2 iron, 2 sulfur cluster binding 9/3206 28/18639 0.321428571428571 1.86871713751003 0.0397534827889708 0.184661339406832 GO:0000340 RNA 7-methylguanosine cap binding 5/3206 12/18639 0.416666666666667 2.42241110417966 0.0410413528676316 0.185977599008568 GO:0000995 RNA polymerase III general transcription initiation factor activity 5/3206 12/18639 0.416666666666667 2.42241110417966 0.0410413528676316 0.185977599008568 GO:0004526 ribonuclease P activity 5/3206 12/18639 0.416666666666667 2.42241110417966 0.0410413528676316 0.185977599008568 GO:0005049 nuclear export signal receptor activity 5/3206 12/18639 0.416666666666667 2.42241110417966 0.0410413528676316 0.185977599008568 GO:0016273 arginine N-methyltransferase activity 5/3206 12/18639 0.416666666666667 2.42241110417966 0.0410413528676316 0.185977599008568 GO:0016274 protein-arginine N-methyltransferase activity 5/3206 12/18639 0.416666666666667 2.42241110417966 0.0410413528676316 0.185977599008568 GO:0031543 peptidyl-proline dioxygenase activity 5/3206 12/18639 0.416666666666667 2.42241110417966 0.0410413528676316 0.185977599008568 GO:0140313 molecular sequestering activity 15/3206 55/18639 0.272727272727273 1.58557817728123 0.0413028437198001 0.186510402302651 GO:0050699 WW domain binding 8/3206 24/18639 0.333333333333333 1.93792888334373 0.0417845508295729 0.188030478733078 GO:0031418 L-ascorbic acid binding 7/3206 20/18639 0.35 2.03482532751092 0.0431705799518998 0.190894044522087 GO:0015923 mannosidase activity 6/3206 16/18639 0.375 2.1801699937617 0.0433046675073254 0.190894044522087 GO:0022858 alanine transmembrane transporter activity 6/3206 16/18639 0.375 2.1801699937617 0.0433046675073254 0.190894044522087 GO:0034450 ubiquitin-ubiquitin ligase activity 6/3206 16/18639 0.375 2.1801699937617 0.0433046675073254 0.190894044522087 GO:0097027 ubiquitin-protein transferase activator activity 6/3206 16/18639 0.375 2.1801699937617 0.0433046675073254 0.190894044522087 GO:0140328 floppase activity 6/3206 16/18639 0.375 2.1801699937617 0.0433046675073254 0.190894044522087 GO:0051879 Hsp90 protein binding 12/3206 42/18639 0.285714285714286 1.66108190000891 0.0463403610874181 0.203583416845064 GO:0003924 GTPase activity 69/3206 331/18639 0.208459214501511 1.21193739834487 0.0471115951066747 0.206272389385981 GO:0016417 S-acyltransferase activity 9/3206 29/18639 0.310344827586207 1.80427861552692 0.0491324197757887 0.212961926519807 GO:0043236 laminin binding 9/3206 29/18639 0.310344827586207 1.80427861552692 0.0491324197757887 0.212961926519807 GO:0051861 glycolipid binding 9/3206 29/18639 0.310344827586207 1.80427861552692 0.0491324197757887 0.212961926519807 GO:0061749 forked DNA-dependent helicase activity 13/3206 47/18639 0.276595744680851 1.60806864788097 0.0497343932129174 0.214138782737345 GO:0140938 histone H3 methyltransferase activity 13/3206 47/18639 0.276595744680851 1.60806864788097 0.0497343932129174 0.214138782737345 GO:0008276 protein methyltransferase activity 23/3206 95/18639 0.242105263157895 1.40754834684966 0.0510424900311964 0.219043268478247 GO:0035401 histone H3Y41 kinase activity 27/3206 115/18639 0.234782608695652 1.36497599609428 0.0519900622690973 0.221562465276642 GO:0140801 histone H2AXY142 kinase activity 27/3206 115/18639 0.234782608695652 1.36497599609428 0.0519900622690973 0.221562465276642 GO:0015662 P-type ion transporter activity 8/3206 25/18639 0.32 1.86041172800998 0.052484318549328 0.221562465276642 GO:0047617 fatty acyl-CoA hydrolase activity 8/3206 25/18639 0.32 1.86041172800998 0.052484318549328 0.221562465276642 GO:0140358 P-type transmembrane transporter activity 8/3206 25/18639 0.32 1.86041172800998 0.052484318549328 0.221562465276642 GO:0035173 histone kinase activity 74/3206 360/18639 0.205555555555556 1.19505614472863 0.0536365617924788 0.225691506763158 GO:0005178 integrin binding 36/3206 161/18639 0.22360248447205 1.29997713913741 0.054246939365595 0.227521143746962 GO:0016504 peptidase activator activity 15/3206 57/18639 0.263157894736842 1.52994385527137 0.0548796027018322 0.22943214548895 GO:0019825 oxygen binding 10/3206 34/18639 0.294117647058824 1.70993725000917 0.0550843996379819 0.229547851867603 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 7/3206 21/18639 0.333333333333333 1.93792888334373 0.0554462518687942 0.229579368760247 GO:0051010 microtubule plus-end binding 7/3206 21/18639 0.333333333333333 1.93792888334373 0.0554462518687942 0.229579368760247 GO:0004029 aldehyde dehydrogenase (NAD+) activity 6/3206 17/18639 0.352941176470588 2.05192470001101 0.0574763657765848 0.23003605858378 GO:0004549 tRNA-specific ribonuclease activity 6/3206 17/18639 0.352941176470588 2.05192470001101 0.0574763657765848 0.23003605858378 GO:0004550 nucleoside diphosphate kinase activity 6/3206 17/18639 0.352941176470588 2.05192470001101 0.0574763657765848 0.23003605858378 GO:0032183 SUMO binding 6/3206 17/18639 0.352941176470588 2.05192470001101 0.0574763657765848 0.23003605858378 GO:0048038 quinone binding 6/3206 17/18639 0.352941176470588 2.05192470001101 0.0574763657765848 0.23003605858378 GO:0008253 5'-nucleotidase activity 5/3206 13/18639 0.384615384615385 2.23607178847354 0.0574928804782958 0.23003605858378 GO:0019855 calcium channel inhibitor activity 5/3206 13/18639 0.384615384615385 2.23607178847354 0.0574928804782958 0.23003605858378 GO:0030955 potassium ion binding 5/3206 13/18639 0.384615384615385 2.23607178847354 0.0574928804782958 0.23003605858378 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 5/3206 13/18639 0.384615384615385 2.23607178847354 0.0574928804782958 0.23003605858378 GO:0140666 annealing activity 5/3206 13/18639 0.384615384615385 2.23607178847354 0.0574928804782958 0.23003605858378 GO:0009378 four-way junction helicase activity 13/3206 48/18639 0.270833333333333 1.57456721771678 0.0578640085635127 0.23003605858378 GO:0016879 ligase activity, forming carbon-nitrogen bonds 13/3206 48/18639 0.270833333333333 1.57456721771678 0.0578640085635127 0.23003605858378 GO:0036121 double-stranded DNA helicase activity 13/3206 48/18639 0.270833333333333 1.57456721771678 0.0578640085635127 0.23003605858378 GO:0042054 histone methyltransferase activity 17/3206 67/18639 0.253731343283582 1.47513989627657 0.0583431103197559 0.231231409707657 GO:0140996 histone H3 kinase activity 73/3206 357/18639 0.204481792717087 1.18881351667304 0.0604148855116943 0.238308296440319 GO:0004518 nuclease activity 45/3206 209/18639 0.215311004784689 1.25177224522203 0.060496473401902 0.238308296440319 GO:0052689 carboxylic ester hydrolase activity 22/3206 92/18639 0.239130434782609 1.39025332935529 0.0623081562581882 0.24470112275943 GO:0008408 3'-5' exonuclease activity 15/3206 58/18639 0.258620689655172 1.5035655129391 0.0627025605132486 0.245056125943328 GO:0004674 protein serine/threonine kinase activity 87/3206 433/18639 0.200923787528868 1.16812803360904 0.0627767236212845 0.245056125943328 GO:0003954 NADH dehydrogenase activity 12/3206 44/18639 0.272727272727273 1.58557817728123 0.0637484925053332 0.247359420020694 GO:0016790 thiolester hydrolase activity 12/3206 44/18639 0.272727272727273 1.58557817728123 0.0637484925053332 0.247359420020694 GO:1901682 sulfur compound transmembrane transporter activity 16/3206 63/18639 0.253968253968254 1.47651724445237 0.0644368636403758 0.249170159597237 GO:0016289 acyl-CoA hydrolase activity 8/3206 26/18639 0.307692307692308 1.78885743077883 0.0647919319323063 0.249170159597237 GO:0050681 nuclear androgen receptor binding 8/3206 26/18639 0.307692307692308 1.78885743077883 0.0647919319323063 0.249170159597237 GO:0141003 histone H2AX kinase activity 72/3206 354/18639 0.203389830508475 1.18246508136228 0.0679156759036626 0.260410402281499 GO:0003925 G protein activity 14/3206 54/18639 0.259259259259259 1.50727802037846 0.0693035974891516 0.264169006899825 GO:0015485 cholesterol binding 14/3206 54/18639 0.259259259259259 1.50727802037846 0.0693035974891516 0.264169006899825 GO:0008649 rRNA methyltransferase activity 7/3206 22/18639 0.318181818181818 1.84984120682811 0.0696792532331315 0.264736846171245 GO:0061791 GTPase motor activity 11/3206 40/18639 0.275 1.59879132875858 0.0702696566997749 0.264736846171245 GO:0071949 FAD binding 11/3206 40/18639 0.275 1.59879132875858 0.0702696566997749 0.264736846171245 GO:1990606 membrane scission GTPase motor activity 11/3206 40/18639 0.275 1.59879132875858 0.0702696566997749 0.264736846171245 GO:0008327 methyl-CpG binding 9/3206 31/18639 0.290322580645161 1.68787354355744 0.0719738530168133 0.268813007232824 GO:0016411 acylglycerol O-acyltransferase activity 9/3206 31/18639 0.290322580645161 1.68787354355744 0.0719738530168133 0.268813007232824 GO:0072349 modified amino acid transmembrane transporter activity 9/3206 31/18639 0.290322580645161 1.68787354355744 0.0719738530168133 0.268813007232824 GO:0051539 4 iron, 4 sulfur cluster binding 12/3206 45/18639 0.266666666666667 1.55034310667498 0.0738743137577907 0.271292283804089 GO:0140303 intramembrane lipid transporter activity 12/3206 45/18639 0.266666666666667 1.55034310667498 0.0738743137577907 0.271292283804089 GO:0002039 p53 binding 17/3206 69/18639 0.246376811594203 1.43238221812363 0.0738949493365125 0.271292283804089 GO:0003746 translation elongation factor activity 6/3206 18/18639 0.333333333333333 1.93792888334373 0.0741029849279686 0.271292283804089 GO:0008525 phosphatidylcholine transporter activity 6/3206 18/18639 0.333333333333333 1.93792888334373 0.0741029849279686 0.271292283804089 GO:0017128 phospholipid scramblase activity 6/3206 18/18639 0.333333333333333 1.93792888334373 0.0741029849279686 0.271292283804089 GO:0098641 cadherin binding involved in cell-cell adhesion 6/3206 18/18639 0.333333333333333 1.93792888334373 0.0741029849279686 0.271292283804089 GO:0046332 SMAD binding 19/3206 79/18639 0.240506329113924 1.39825248545054 0.075319352819686 0.272043145659653 GO:0004527 exonuclease activity 20/3206 84/18639 0.238095238095238 1.38423491667409 0.0756859454586749 0.272043145659653 GO:0005528 FK506 binding 4/3206 10/18639 0.4 2.32551466001248 0.0768269994686982 0.272043145659653 GO:0016783 sulfurtransferase activity 4/3206 10/18639 0.4 2.32551466001248 0.0768269994686982 0.272043145659653 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 4/3206 10/18639 0.4 2.32551466001248 0.0768269994686982 0.272043145659653 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 4/3206 10/18639 0.4 2.32551466001248 0.0768269994686982 0.272043145659653 GO:0140940 histone H2A methyltransferase activity 4/3206 10/18639 0.4 2.32551466001248 0.0768269994686982 0.272043145659653 GO:0140999 histone H3K4 trimethyltransferase activity 4/3206 10/18639 0.4 2.32551466001248 0.0768269994686982 0.272043145659653 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 4/3206 10/18639 0.4 2.32551466001248 0.0768269994686982 0.272043145659653 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 4/3206 10/18639 0.4 2.32551466001248 0.0768269994686982 0.272043145659653 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 4/3206 10/18639 0.4 2.32551466001248 0.0768269994686982 0.272043145659653 GO:1990259 histone H2AQ104 methyltransferase activity 4/3206 10/18639 0.4 2.32551466001248 0.0768269994686982 0.272043145659653 GO:0044548 S100 protein binding 5/3206 14/18639 0.357142857142857 2.07635237501114 0.0771723164765325 0.272521313769989 GO:0016409 palmitoyltransferase activity 10/3206 36/18639 0.277777777777778 1.61494073611978 0.0774959326762313 0.272920458555423 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 15/3206 60/18639 0.25 1.4534466625078 0.0805188310526102 0.282797845648192 GO:0031267 small GTPase binding 58/3206 283/18639 0.204946996466431 1.19151811202053 0.0828751966887329 0.290125998834399 GO:0043130 ubiquitin binding 23/3206 100/18639 0.23 1.33717092950717 0.0830530444194152 0.290125998834399 GO:0008171 O-methyltransferase activity 7/3206 23/18639 0.304347826086957 1.76941332827036 0.085886809266521 0.298416366781263 GO:0140102 catalytic activity, acting on a rRNA 7/3206 23/18639 0.304347826086957 1.76941332827036 0.085886809266521 0.298416366781263 GO:0019212 phosphatase inhibitor activity 14/3206 56/18639 0.25 1.4534466625078 0.0892349355967059 0.309220525490189 GO:0008237 metallopeptidase activity 39/3206 184/18639 0.21195652173913 1.232269996474 0.0917044374328817 0.316930535768039 GO:0050660 flavin adenine dinucleotide binding 20/3206 86/18639 0.232558139534884 1.352043406984 0.0921208930877516 0.317523078302463 GO:0008301 DNA binding, bending 6/3206 19/18639 0.315789473684211 1.83593262632564 0.0931682408251684 0.319211593040488 GO:0042800 histone H3K4 methyltransferase activity 6/3206 19/18639 0.315789473684211 1.83593262632564 0.0931682408251684 0.319211593040488 GO:0004519 endonuclease activity 28/3206 127/18639 0.220472440944882 1.28177973386514 0.0937954462352386 0.319211593040488 GO:0106310 protein serine kinase activity 72/3206 361/18639 0.199445983379501 1.15953639557409 0.0943074922291942 0.319211593040488 GO:0046625 sphingolipid binding 8/3206 28/18639 0.285714285714286 1.66108190000891 0.0943349075111935 0.319211593040488 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 8/3206 28/18639 0.285714285714286 1.66108190000891 0.0943349075111935 0.319211593040488 GO:0097718 disordered domain specific binding 8/3206 28/18639 0.285714285714286 1.66108190000891 0.0943349075111935 0.319211593040488 GO:0043495 protein-membrane adaptor activity 12/3206 47/18639 0.25531914893617 1.48437105958243 0.0970561867627825 0.326982034882402 GO:0004857 enzyme inhibitor activity 82/3206 416/18639 0.197115384615385 1.14598679159269 0.0971358668439236 0.326982034882402 GO:0008238 exopeptidase activity 23/3206 102/18639 0.225490196078431 1.3109518916737 0.0989516233728528 0.332231357231133 GO:0004129 cytochrome-c oxidase activity 5/3206 15/18639 0.333333333333333 1.93792888334373 0.0999884168347351 0.333123363027806 GO:0008252 nucleotidase activity 5/3206 15/18639 0.333333333333333 1.93792888334373 0.0999884168347351 0.333123363027806 GO:0015556 C4-dicarboxylate transmembrane transporter activity 5/3206 15/18639 0.333333333333333 1.93792888334373 0.0999884168347351 0.333123363027806 GO:0043178 alcohol binding 21/3206 92/18639 0.228260869565217 1.32705999620277 0.100523496404457 0.334047311128656 GO:0050431 transforming growth factor beta binding 7/3206 24/18639 0.291666666666667 1.69568777292576 0.104046562740558 0.334673440206546 GO:0000099 sulfur amino acid transmembrane transporter activity 4/3206 11/18639 0.363636363636364 2.11410423637498 0.104843685743717 0.334673440206546 GO:0002162 dystroglycan binding 4/3206 11/18639 0.363636363636364 2.11410423637498 0.104843685743717 0.334673440206546 GO:0004523 RNA-DNA hybrid ribonuclease activity 4/3206 11/18639 0.363636363636364 2.11410423637498 0.104843685743717 0.334673440206546 GO:0005114 type II transforming growth factor beta receptor binding 4/3206 11/18639 0.363636363636364 2.11410423637498 0.104843685743717 0.334673440206546 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 4/3206 11/18639 0.363636363636364 2.11410423637498 0.104843685743717 0.334673440206546 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 4/3206 11/18639 0.363636363636364 2.11410423637498 0.104843685743717 0.334673440206546 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 4/3206 11/18639 0.363636363636364 2.11410423637498 0.104843685743717 0.334673440206546 GO:0019206 nucleoside kinase activity 4/3206 11/18639 0.363636363636364 2.11410423637498 0.104843685743717 0.334673440206546 GO:0032050 clathrin heavy chain binding 4/3206 11/18639 0.363636363636364 2.11410423637498 0.104843685743717 0.334673440206546 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 4/3206 11/18639 0.363636363636364 2.11410423637498 0.104843685743717 0.334673440206546 GO:0034713 type I transforming growth factor beta receptor binding 4/3206 11/18639 0.363636363636364 2.11410423637498 0.104843685743717 0.334673440206546 GO:0045294 alpha-catenin binding 4/3206 11/18639 0.363636363636364 2.11410423637498 0.104843685743717 0.334673440206546 GO:0097493 structural molecule activity conferring elasticity 4/3206 11/18639 0.363636363636364 2.11410423637498 0.104843685743717 0.334673440206546 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 4/3206 11/18639 0.363636363636364 2.11410423637498 0.104843685743717 0.334673440206546 GO:1990948 ubiquitin ligase inhibitor activity 4/3206 11/18639 0.363636363636364 2.11410423637498 0.104843685743717 0.334673440206546 GO:0008170 N-methyltransferase activity 22/3206 98/18639 0.224489795918367 1.30513577857843 0.108712711352957 0.346171188976493 GO:0034212 protein N-acetyltransferase activity 13/3206 53/18639 0.245283018867925 1.42602314057369 0.111557579714434 0.353577361442422 GO:0008194 UDP-glycosyltransferase activity 31/3206 145/18639 0.213793103448276 1.24294749069632 0.111584213603357 0.353577361442422 GO:0004521 RNA endonuclease activity 17/3206 73/18639 0.232876712328767 1.35389552124014 0.112645409676807 0.355090963530355 GO:0003777 microtubule motor activity 16/3206 68/18639 0.235294117647059 1.36794980000734 0.112883855690205 0.355090963530355 GO:0032934 sterol binding 16/3206 68/18639 0.235294117647059 1.36794980000734 0.112883855690205 0.355090963530355 GO:0030742 GTP-dependent protein binding 6/3206 20/18639 0.3 1.74413599500936 0.114595809770855 0.359603315891109 GO:0015297 antiporter activity 29/3206 135/18639 0.214814814814815 1.24888750259929 0.115235702304175 0.36073785069133 GO:0016831 carboxy-lyase activity 9/3206 34/18639 0.264705882352941 1.53894352500826 0.116753759549025 0.362860605217113 GO:0030332 cyclin binding 9/3206 34/18639 0.264705882352941 1.53894352500826 0.116753759549025 0.362860605217113 GO:0090482 vitamin transmembrane transporter activity 9/3206 34/18639 0.264705882352941 1.53894352500826 0.116753759549025 0.362860605217113 GO:0035402 histone H3T11 kinase activity 50/3206 247/18639 0.202429149797571 1.17687988867028 0.118170501404577 0.366385095263953 GO:0016776 phosphotransferase activity, phosphate group as acceptor 10/3206 39/18639 0.256410256410256 1.49071452564902 0.120314691856278 0.371256763442229 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 10/3206 39/18639 0.256410256410256 1.49071452564902 0.120314691856278 0.371256763442229 GO:0016779 nucleotidyltransferase activity 29/3206 136/18639 0.213235294117647 1.23970450625665 0.123476512506486 0.375522741105488 GO:0140789 histone phosphatase activity 29/3206 136/18639 0.213235294117647 1.23970450625665 0.123476512506486 0.375522741105488 GO:0000030 mannosyltransferase activity 7/3206 25/18639 0.28 1.62786026200873 0.124098546592703 0.375522741105488 GO:0017025 TBP-class protein binding 7/3206 25/18639 0.28 1.62786026200873 0.124098546592703 0.375522741105488 GO:0019706 protein-cysteine S-palmitoyltransferase activity 7/3206 25/18639 0.28 1.62786026200873 0.124098546592703 0.375522741105488 GO:0019707 protein-cysteine S-acyltransferase activity 7/3206 25/18639 0.28 1.62786026200873 0.124098546592703 0.375522741105488 GO:0042974 nuclear retinoic acid receptor binding 7/3206 25/18639 0.28 1.62786026200873 0.124098546592703 0.375522741105488 GO:0008080 N-acetyltransferase activity 16/3206 69/18639 0.231884057971014 1.34812444058694 0.124654091570566 0.375522741105488 GO:0050661 NADP binding 13/3206 54/18639 0.240740740740741 1.39961530463714 0.124955183834645 0.375522741105488 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 5/3206 16/18639 0.3125 1.81680832813475 0.125753757438103 0.375522741105488 GO:0005159 insulin-like growth factor receptor binding 5/3206 16/18639 0.3125 1.81680832813475 0.125753757438103 0.375522741105488 GO:0005324 long-chain fatty acid transmembrane transporter activity 5/3206 16/18639 0.3125 1.81680832813475 0.125753757438103 0.375522741105488 GO:0008142 oxysterol binding 5/3206 16/18639 0.3125 1.81680832813475 0.125753757438103 0.375522741105488 GO:0016675 oxidoreductase activity, acting on a heme group of donors 5/3206 16/18639 0.3125 1.81680832813475 0.125753757438103 0.375522741105488 GO:0016769 transferase activity, transferring nitrogenous groups 8/3206 30/18639 0.266666666666667 1.55034310667498 0.130353306609563 0.387472214142187 GO:0031210 phosphatidylcholine binding 8/3206 30/18639 0.266666666666667 1.55034310667498 0.130353306609563 0.387472214142187 GO:0022804 active transmembrane transporter activity 88/3206 457/18639 0.192560175054705 1.11950377506071 0.132766506957806 0.393742318117428 GO:0005025 transforming growth factor beta receptor activity, type I 4/3206 12/18639 0.333333333333333 1.93792888334373 0.13674485218176 0.394668062289552 GO:0005026 transforming growth factor beta receptor activity, type II 4/3206 12/18639 0.333333333333333 1.93792888334373 0.13674485218176 0.394668062289552 GO:0005095 GTPase inhibitor activity 4/3206 12/18639 0.333333333333333 1.93792888334373 0.13674485218176 0.394668062289552 GO:0005527 macrolide binding 4/3206 12/18639 0.333333333333333 1.93792888334373 0.13674485218176 0.394668062289552 GO:0016361 activin receptor activity, type I 4/3206 12/18639 0.333333333333333 1.93792888334373 0.13674485218176 0.394668062289552 GO:0016362 activin receptor activity, type II 4/3206 12/18639 0.333333333333333 1.93792888334373 0.13674485218176 0.394668062289552 GO:0017002 activin receptor activity 4/3206 12/18639 0.333333333333333 1.93792888334373 0.13674485218176 0.394668062289552 GO:0036009 protein-glutamine N-methyltransferase activity 4/3206 12/18639 0.333333333333333 1.93792888334373 0.13674485218176 0.394668062289552 GO:0097677 STAT family protein binding 4/3206 12/18639 0.333333333333333 1.93792888334373 0.13674485218176 0.394668062289552 GO:0141221 histone deacetylase activity, hydrolytic mechanism 4/3206 12/18639 0.333333333333333 1.93792888334373 0.13674485218176 0.394668062289552 GO:0050997 quaternary ammonium group binding 10/3206 40/18639 0.25 1.4534466625078 0.136996370241779 0.394668062289552 GO:0097110 scaffold protein binding 16/3206 70/18639 0.228571428571429 1.32886552000713 0.137110273106851 0.394668062289552 GO:0160215 deacylase activity 15/3206 65/18639 0.230769230769231 1.34164307308412 0.138110827466845 0.394668062289552 GO:0009931 calcium-dependent protein serine/threonine kinase activity 6/3206 21/18639 0.285714285714286 1.66108190000891 0.138255632931679 0.394668062289552 GO:0010314 phosphatidylinositol-5-phosphate binding 6/3206 21/18639 0.285714285714286 1.66108190000891 0.138255632931679 0.394668062289552 GO:0019200 carbohydrate kinase activity 6/3206 21/18639 0.285714285714286 1.66108190000891 0.138255632931679 0.394668062289552 GO:1904047 S-adenosyl-L-methionine binding 6/3206 21/18639 0.285714285714286 1.66108190000891 0.138255632931679 0.394668062289552 GO:0008374 O-acyltransferase activity 13/3206 55/18639 0.236363636363636 1.37416775364374 0.13922124558617 0.394870436664507 GO:0098632 cell-cell adhesion mediator activity 13/3206 55/18639 0.236363636363636 1.37416775364374 0.13922124558617 0.394870436664507 GO:0004721 phosphoprotein phosphatase activity 36/3206 175/18639 0.205714285714286 1.19597896800642 0.139240578360864 0.394870436664507 GO:0005200 structural constituent of cytoskeleton 24/3206 112/18639 0.214285714285714 1.24581142500668 0.144209834190347 0.408069749149976 GO:0120014 phospholipid transfer activity 7/3206 26/18639 0.269230769230769 1.56525025193147 0.145948351993902 0.412089464453371 GO:0019903 protein phosphatase binding 30/3206 144/18639 0.208333333333333 1.21120555208983 0.147434348282682 0.415380250813816 GO:0098631 cell adhesion mediator activity 17/3206 76/18639 0.223684210526316 1.30045227698066 0.148478079653507 0.417413430002049 GO:0017110 nucleoside diphosphate phosphatase activity 5/3206 17/18639 0.294117647058824 1.70993725000917 0.154202670630403 0.430142081756868 GO:0046965 nuclear retinoid X receptor binding 5/3206 17/18639 0.294117647058824 1.70993725000917 0.154202670630403 0.430142081756868 GO:1990226 histone methyltransferase binding 5/3206 17/18639 0.294117647058824 1.70993725000917 0.154202670630403 0.430142081756868 GO:0030170 pyridoxal phosphate binding 13/3206 56/18639 0.232142857142857 1.34962904375724 0.154333385815543 0.430142081756868 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 10/3206 41/18639 0.24390243902439 1.41799674391005 0.154822364505909 0.430321094549554 GO:0016830 carbon-carbon lyase activity 12/3206 51/18639 0.235294117647059 1.36794980000734 0.155061690705742 0.430321094549554 GO:0035591 signaling adaptor activity 27/3206 129/18639 0.209302325581395 1.2168390662856 0.156276991796354 0.432767054205288 GO:0004713 protein tyrosine kinase activity 29/3206 140/18639 0.207142857142857 1.20428437750646 0.159963320376498 0.442030838396463 GO:0046982 protein heterodimerization activity 71/3206 369/18639 0.192411924119241 1.11864187575126 0.16344522228534 0.449124221241435 GO:0008093 cytoskeletal anchor activity 6/3206 22/18639 0.272727272727273 1.58557817728123 0.163971775318635 0.449124221241435 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 6/3206 22/18639 0.272727272727273 1.58557817728123 0.163971775318635 0.449124221241435 GO:0061133 endopeptidase activator activity 6/3206 22/18639 0.272727272727273 1.58557817728123 0.163971775318635 0.449124221241435 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 48/3206 243/18639 0.197530864197531 1.14840230124073 0.164263025361451 0.449124221241435 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 7/3206 27/18639 0.259259259259259 1.50727802037846 0.169471200035073 0.459526730162385 GO:0070279 vitamin B6 binding 13/3206 57/18639 0.228070175438596 1.32595134123518 0.170262224655639 0.459526730162385 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 4/3206 13/18639 0.307692307692308 1.78885743077883 0.171967950716633 0.459526730162385 GO:0005542 folic acid binding 4/3206 13/18639 0.307692307692308 1.78885743077883 0.171967950716633 0.459526730162385 GO:0046975 histone H3K36 methyltransferase activity 4/3206 13/18639 0.307692307692308 1.78885743077883 0.171967950716633 0.459526730162385 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 4/3206 13/18639 0.307692307692308 1.78885743077883 0.171967950716633 0.459526730162385 GO:0061459 L-arginine transmembrane transporter activity 4/3206 13/18639 0.307692307692308 1.78885743077883 0.171967950716633 0.459526730162385 GO:0070123 transforming growth factor beta receptor activity, type III 4/3206 13/18639 0.307692307692308 1.78885743077883 0.171967950716633 0.459526730162385 GO:0097157 pre-mRNA intronic binding 4/3206 13/18639 0.307692307692308 1.78885743077883 0.171967950716633 0.459526730162385 GO:0140333 glycerophospholipid flippase activity 4/3206 13/18639 0.307692307692308 1.78885743077883 0.171967950716633 0.459526730162385 GO:0140410 monoatomic cation:bicarbonate symporter activity 4/3206 13/18639 0.307692307692308 1.78885743077883 0.171967950716633 0.459526730162385 GO:0061733 protein-lysine-acetyltransferase activity 11/3206 47/18639 0.234042553191489 1.3606734712839 0.173077154637673 0.460250766573765 GO:0140359 ABC-type transporter activity 11/3206 47/18639 0.234042553191489 1.3606734712839 0.173077154637673 0.460250766573765 GO:0048487 beta-tubulin binding 10/3206 42/18639 0.238095238095238 1.38423491667409 0.173737023524857 0.460250766573765 GO:0016410 N-acyltransferase activity 20/3206 94/18639 0.212765957446809 1.23697588298536 0.179155217169375 0.460250766573765 GO:0004676 3-phosphoinositide-dependent protein kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:0004711 ribosomal protein S6 kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:0035175 histone H3S10 kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:0035979 histone H2AXS139 kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:0044022 histone H3S28 kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:0044023 histone H4S1 kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:0044024 histone H2AS1 kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:0044025 histone H2BS14 kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:0072354 histone H3T3 kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:0072371 histone H2AS121 kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:0072518 Rho-dependent protein serine/threonine kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:0140823 histone H2BS36 kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:0140855 histone H3S57 kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:0140995 histone H2A kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:0140997 histone H4 kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:0140998 histone H2B kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:1990244 histone H2AT120 kinase activity 48/3206 245/18639 0.195918367346939 1.13902758857754 0.179696672751794 0.460250766573765 GO:0004222 metalloendopeptidase activity 23/3206 110/18639 0.209090909090909 1.21560993591561 0.180741340683885 0.462013367902002 GO:0000900 mRNA regulatory element binding translation repressor activity 5/3206 18/18639 0.277777777777778 1.61494073611978 0.185010242054416 0.471067335368414 GO:0008308 voltage-gated monoatomic anion channel activity 5/3206 18/18639 0.277777777777778 1.61494073611978 0.185010242054416 0.471067335368414 GO:0004677 DNA-dependent protein kinase activity 48/3206 246/18639 0.195121951219512 1.13439739512804 0.187707184860664 0.476063623443093 GO:0140857 histone H3T45 kinase activity 48/3206 246/18639 0.195121951219512 1.13439739512804 0.187707184860664 0.476063623443093 GO:0016835 carbon-oxygen lyase activity 17/3206 79/18639 0.215189873417722 1.25106801329785 0.189842456533681 0.480538718100881 GO:0004712 protein serine/threonine/tyrosine kinase activity 10/3206 43/18639 0.232558139534884 1.352043406984 0.193673109451285 0.489279434403246 GO:0042887 amide transmembrane transporter activity 9/3206 38/18639 0.236842105263158 1.37694946974423 0.194971032649406 0.491600113450642 GO:0035403 histone H3T6 kinase activity 48/3206 247/18639 0.194331983805668 1.12980469312347 0.195909419703323 0.493007005700014 GO:0004679 AMP-activated protein kinase activity 48/3206 248/18639 0.193548387096774 1.1252490290383 0.204299848384676 0.513125200594069 GO:0051287 NAD binding 12/3206 54/18639 0.222222222222222 1.29195258889582 0.207965439830916 0.514201362795511 GO:0004705 JUN kinase activity 4/3206 14/18639 0.285714285714286 1.66108190000891 0.209886204412674 0.514201362795511 GO:0005161 platelet-derived growth factor receptor binding 4/3206 14/18639 0.285714285714286 1.66108190000891 0.209886204412674 0.514201362795511 GO:0005545 1-phosphatidylinositol binding 4/3206 14/18639 0.285714285714286 1.66108190000891 0.209886204412674 0.514201362795511 GO:0008174 mRNA methyltransferase activity 4/3206 14/18639 0.285714285714286 1.66108190000891 0.209886204412674 0.514201362795511 GO:0008474 palmitoyl-(protein) hydrolase activity 4/3206 14/18639 0.285714285714286 1.66108190000891 0.209886204412674 0.514201362795511 GO:0016530 metallochaperone activity 4/3206 14/18639 0.285714285714286 1.66108190000891 0.209886204412674 0.514201362795511 GO:0019992 diacylglycerol binding 4/3206 14/18639 0.285714285714286 1.66108190000891 0.209886204412674 0.514201362795511 GO:0070742 C2H2 zinc finger domain binding 4/3206 14/18639 0.285714285714286 1.66108190000891 0.209886204412674 0.514201362795511 GO:0098599 palmitoyl hydrolase activity 4/3206 14/18639 0.285714285714286 1.66108190000891 0.209886204412674 0.514201362795511 GO:0098821 BMP receptor activity 4/3206 14/18639 0.285714285714286 1.66108190000891 0.209886204412674 0.514201362795511 GO:0098847 sequence-specific single stranded DNA binding 4/3206 14/18639 0.285714285714286 1.66108190000891 0.209886204412674 0.514201362795511 GO:1901612 cardiolipin binding 4/3206 14/18639 0.285714285714286 1.66108190000891 0.209886204412674 0.514201362795511 GO:0015171 amino acid transmembrane transporter activity 21/3206 102/18639 0.205882352941176 1.19695607500642 0.2150482903086 0.525666666640176 GO:0005319 lipid transporter activity 35/3206 178/18639 0.196629213483146 1.14316029635445 0.216639996639852 0.525666666640176 GO:0016829 lyase activity 39/3206 200/18639 0.195 1.13368839675608 0.21757678599214 0.525666666640176 GO:0008574 plus-end-directed microtubule motor activity 5/3206 19/18639 0.263157894736842 1.52994385527137 0.217810956779147 0.525666666640176 GO:0015245 fatty acid transmembrane transporter activity 5/3206 19/18639 0.263157894736842 1.52994385527137 0.217810956779147 0.525666666640176 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 5/3206 19/18639 0.263157894736842 1.52994385527137 0.217810956779147 0.525666666640176 GO:0031420 alkali metal ion binding 5/3206 19/18639 0.263157894736842 1.52994385527137 0.217810956779147 0.525666666640176 GO:0097001 ceramide binding 5/3206 19/18639 0.263157894736842 1.52994385527137 0.217810956779147 0.525666666640176 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 8/3206 34/18639 0.235294117647059 1.36794980000734 0.219604260794805 0.529009520427634 GO:0005540 hyaluronic acid binding 6/3206 24/18639 0.25 1.4534466625078 0.220692712555459 0.53064518640422 GO:0005201 extracellular matrix structural constituent 33/3206 168/18639 0.196428571428571 1.14199380625613 0.226631785409204 0.543916284982089 GO:0004722 protein serine/threonine phosphatase activity 21/3206 103/18639 0.203883495145631 1.18533514223937 0.229008818708963 0.548605229291712 GO:0042626 ATPase-coupled transmembrane transporter activity 20/3206 98/18639 0.204081632653061 1.18648707143494 0.234559976513229 0.556897066358366 GO:0002020 protease binding 27/3206 136/18639 0.198529411764706 1.15420764375619 0.23549428361668 0.556897066358366 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 17/3206 82/18639 0.207317073170732 1.20529723232354 0.236169233317309 0.556897066358366 GO:0000182 rDNA binding 3/3206 10/18639 0.3 1.74413599500936 0.239775125793185 0.556897066358366 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 3/3206 10/18639 0.3 1.74413599500936 0.239775125793185 0.556897066358366 GO:0003680 minor groove of adenine-thymine-rich DNA binding 3/3206 10/18639 0.3 1.74413599500936 0.239775125793185 0.556897066358366 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 3/3206 10/18639 0.3 1.74413599500936 0.239775125793185 0.556897066358366 GO:0016303 1-phosphatidylinositol-3-kinase activity 3/3206 10/18639 0.3 1.74413599500936 0.239775125793185 0.556897066358366 GO:0016868 intramolecular phosphotransferase activity 3/3206 10/18639 0.3 1.74413599500936 0.239775125793185 0.556897066358366 GO:0031419 cobalamin binding 3/3206 10/18639 0.3 1.74413599500936 0.239775125793185 0.556897066358366 GO:0031957 very long-chain fatty acid-CoA ligase activity 3/3206 10/18639 0.3 1.74413599500936 0.239775125793185 0.556897066358366 GO:0031996 thioesterase binding 3/3206 10/18639 0.3 1.74413599500936 0.239775125793185 0.556897066358366 GO:0042975 peroxisome proliferator activated receptor binding 3/3206 10/18639 0.3 1.74413599500936 0.239775125793185 0.556897066358366 GO:0051880 G-quadruplex DNA binding 3/3206 10/18639 0.3 1.74413599500936 0.239775125793185 0.556897066358366 GO:0098505 G-rich strand telomeric DNA binding 3/3206 10/18639 0.3 1.74413599500936 0.239775125793185 0.556897066358366 GO:0099122 RNA polymerase II C-terminal domain binding 3/3206 10/18639 0.3 1.74413599500936 0.239775125793185 0.556897066358366 GO:1990757 ubiquitin ligase activator activity 3/3206 10/18639 0.3 1.74413599500936 0.239775125793185 0.556897066358366 GO:0051213 dioxygenase activity 19/3206 93/18639 0.204301075268817 1.18776286398487 0.240327196883346 0.557052308874413 GO:0030331 nuclear estrogen receptor binding 9/3206 40/18639 0.225 1.30810199625702 0.240701614945734 0.557052308874413 GO:0010485 histone H4 acetyltransferase activity 8/3206 35/18639 0.228571428571429 1.32886552000713 0.244840291295467 0.565620352083646 GO:0005518 collagen binding 15/3206 72/18639 0.208333333333333 1.21120555208983 0.247947336168327 0.569076188035008 GO:0051721 protein phosphatase 2A binding 7/3206 30/18639 0.233333333333333 1.35655021834061 0.248475355826844 0.569076188035008 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 4/3206 15/18639 0.266666666666667 1.55034310667498 0.249849036259197 0.569076188035008 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 4/3206 15/18639 0.266666666666667 1.55034310667498 0.249849036259197 0.569076188035008 GO:0034483 heparan sulfate sulfotransferase activity 4/3206 15/18639 0.266666666666667 1.55034310667498 0.249849036259197 0.569076188035008 GO:0140776 protein-containing complex destabilizing activity 4/3206 15/18639 0.266666666666667 1.55034310667498 0.249849036259197 0.569076188035008 GO:0141050 histone H3K deacetylase activity 4/3206 15/18639 0.266666666666667 1.55034310667498 0.249849036259197 0.569076188035008 GO:0141051 histone H4K deacetylase activity 4/3206 15/18639 0.266666666666667 1.55034310667498 0.249849036259197 0.569076188035008 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 6/3206 25/18639 0.24 1.39530879600749 0.251196133385803 0.570457143967462 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 5/3206 20/18639 0.25 1.4534466625078 0.25221600578191 0.570457143967462 GO:0016408 C-acyltransferase activity 5/3206 20/18639 0.25 1.4534466625078 0.25221600578191 0.570457143967462 GO:0042288 MHC class I protein binding 5/3206 20/18639 0.25 1.4534466625078 0.25221600578191 0.570457143967462 GO:0030544 Hsp70 protein binding 11/3206 51/18639 0.215686274509804 1.25395398334006 0.252833101590467 0.570856619618895 GO:0050840 extracellular matrix binding 14/3206 67/18639 0.208955223880597 1.21482109105129 0.254190723818554 0.572923787945819 GO:0030291 protein serine/threonine kinase inhibitor activity 10/3206 46/18639 0.217391304347826 1.26386666305026 0.258792299007408 0.582282672766667 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 18/3206 89/18639 0.202247191011236 1.17582201910743 0.262465505535898 0.588467518032991 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 18/3206 89/18639 0.202247191011236 1.17582201910743 0.262465505535898 0.588467518032991 GO:0019787 ubiquitin-like protein transferase activity 88/3206 479/18639 0.183716075156576 1.06808606514143 0.262903312454554 0.588467518032991 GO:0042277 peptide binding 47/3206 249/18639 0.188755020080321 1.09738141586934 0.263839933674089 0.589545782830379 GO:0015932 nucleobase-containing compound transmembrane transporter activity 12/3206 57/18639 0.210526315789474 1.22395508421709 0.26747468796799 0.596638890889009 GO:1990782 protein tyrosine kinase binding 23/3206 117/18639 0.196581196581197 1.14288113633092 0.273896922907425 0.6099147974021 GO:0140793 histone H2AXY142 phosphatase activity 18/3206 90/18639 0.2 1.16275733000624 0.278986192490551 0.612684271822455 GO:0005507 copper ion binding 13/3206 63/18639 0.206349206349206 1.19967026111755 0.280571304722625 0.612684271822455 GO:0001784 phosphotyrosine residue binding 10/3206 47/18639 0.212765957446809 1.23697588298536 0.281958554242471 0.612684271822455 GO:0004529 DNA exonuclease activity 6/3206 26/18639 0.230769230769231 1.34164307308412 0.282770467803373 0.612684271822455 GO:0008198 ferrous iron binding 6/3206 26/18639 0.230769230769231 1.34164307308412 0.282770467803373 0.612684271822455 GO:0030507 spectrin binding 6/3206 26/18639 0.230769230769231 1.34164307308412 0.282770467803373 0.612684271822455 GO:0052742 phosphatidylinositol kinase activity 6/3206 26/18639 0.230769230769231 1.34164307308412 0.282770467803373 0.612684271822455 GO:0070412 R-SMAD binding 6/3206 26/18639 0.230769230769231 1.34164307308412 0.282770467803373 0.612684271822455 GO:0008373 sialyltransferase activity 5/3206 21/18639 0.238095238095238 1.38423491667409 0.287828622297608 0.612684271822455 GO:0004520 DNA endonuclease activity 9/3206 42/18639 0.214285714285714 1.24581142500668 0.28970555338841 0.612684271822455 GO:0008307 structural constituent of muscle 9/3206 42/18639 0.214285714285714 1.24581142500668 0.28970555338841 0.612684271822455 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 3/3206 11/18639 0.272727272727273 1.58557817728123 0.290374415811736 0.612684271822455 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 3/3206 11/18639 0.272727272727273 1.58557817728123 0.290374415811736 0.612684271822455 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 3/3206 11/18639 0.272727272727273 1.58557817728123 0.290374415811736 0.612684271822455 GO:0008172 S-methyltransferase activity 3/3206 11/18639 0.272727272727273 1.58557817728123 0.290374415811736 0.612684271822455 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 3/3206 11/18639 0.272727272727273 1.58557817728123 0.290374415811736 0.612684271822455 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 3/3206 11/18639 0.272727272727273 1.58557817728123 0.290374415811736 0.612684271822455 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 3/3206 11/18639 0.272727272727273 1.58557817728123 0.290374415811736 0.612684271822455 GO:0032794 GTPase activating protein binding 3/3206 11/18639 0.272727272727273 1.58557817728123 0.290374415811736 0.612684271822455 GO:0035252 UDP-xylosyltransferase activity 3/3206 11/18639 0.272727272727273 1.58557817728123 0.290374415811736 0.612684271822455 GO:0042285 xylosyltransferase activity 3/3206 11/18639 0.272727272727273 1.58557817728123 0.290374415811736 0.612684271822455 GO:0043522 leucine zipper domain binding 3/3206 11/18639 0.272727272727273 1.58557817728123 0.290374415811736 0.612684271822455 GO:0050786 RAGE receptor binding 3/3206 11/18639 0.272727272727273 1.58557817728123 0.290374415811736 0.612684271822455 GO:0050998 nitric-oxide synthase binding 3/3206 11/18639 0.272727272727273 1.58557817728123 0.290374415811736 0.612684271822455 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 3/3206 11/18639 0.272727272727273 1.58557817728123 0.290374415811736 0.612684271822455 GO:0180030 inositol phosphate kinase activity 3/3206 11/18639 0.272727272727273 1.58557817728123 0.290374415811736 0.612684271822455 GO:0004707 MAP kinase activity 4/3206 16/18639 0.25 1.4534466625078 0.291214129199562 0.612684271822455 GO:0005024 transforming growth factor beta receptor activity 4/3206 16/18639 0.25 1.4534466625078 0.291214129199562 0.612684271822455 GO:0008296 3'-5'-DNA exonuclease activity 4/3206 16/18639 0.25 1.4534466625078 0.291214129199562 0.612684271822455 GO:0015562 efflux transmembrane transporter activity 4/3206 16/18639 0.25 1.4534466625078 0.291214129199562 0.612684271822455 GO:0019841 retinol binding 4/3206 16/18639 0.25 1.4534466625078 0.291214129199562 0.612684271822455 GO:0030275 LRR domain binding 4/3206 16/18639 0.25 1.4534466625078 0.291214129199562 0.612684271822455 GO:0070411 I-SMAD binding 4/3206 16/18639 0.25 1.4534466625078 0.291214129199562 0.612684271822455 GO:0140327 flippase activity 4/3206 16/18639 0.25 1.4534466625078 0.291214129199562 0.612684271822455 GO:0016279 protein-lysine N-methyltransferase activity 14/3206 69/18639 0.202898550724638 1.17960888551358 0.292392487346022 0.614166391572844 GO:0004864 protein phosphatase inhibitor activity 11/3206 53/18639 0.207547169811321 1.20663496510081 0.296827262125377 0.622472705039626 GO:0022829 wide pore channel activity 8/3206 37/18639 0.216216216216216 1.2570349513581 0.297816094989657 0.623537413742481 GO:0046906 tetrapyrrole binding 29/3206 152/18639 0.190789473684211 1.10920929507174 0.299683669192819 0.626435540764343 GO:0004536 DNA nuclease activity 13/3206 64/18639 0.203125 1.18092541328759 0.300905657221771 0.627977023767175 GO:0019003 GDP binding 15/3206 75/18639 0.2 1.16275733000624 0.303146298736123 0.631628083400399 GO:0016755 aminoacyltransferase activity 90/3206 496/18639 0.181451612903226 1.0549209647234 0.30362985799263 0.631628083400399 GO:0140693 molecular condensate scaffold activity 10/3206 48/18639 0.208333333333333 1.21120555208983 0.305686049207983 0.63412925592482 GO:0042910 xenobiotic transmembrane transporter activity 7/3206 32/18639 0.21875 1.27176582969432 0.30630008812418 0.63412925592482 GO:0043425 bHLH transcription factor binding 7/3206 32/18639 0.21875 1.27176582969432 0.30630008812418 0.63412925592482 GO:0016278 lysine N-methyltransferase activity 14/3206 70/18639 0.2 1.16275733000624 0.31211180004479 0.638807779341935 GO:0033192 calmodulin-dependent protein phosphatase activity 16/3206 81/18639 0.197530864197531 1.14840230124073 0.312996095588062 0.638807779341935 GO:0140791 histone H2AXS140 phosphatase activity 16/3206 81/18639 0.197530864197531 1.14840230124073 0.312996095588062 0.638807779341935 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 16/3206 81/18639 0.197530864197531 1.14840230124073 0.312996095588062 0.638807779341935 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 16/3206 81/18639 0.197530864197531 1.14840230124073 0.312996095588062 0.638807779341935 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 16/3206 81/18639 0.197530864197531 1.14840230124073 0.312996095588062 0.638807779341935 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 16/3206 81/18639 0.197530864197531 1.14840230124073 0.312996095588062 0.638807779341935 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 16/3206 81/18639 0.197530864197531 1.14840230124073 0.312996095588062 0.638807779341935 GO:1990439 MAP kinase serine/threonine phosphatase activity 16/3206 81/18639 0.197530864197531 1.14840230124073 0.312996095588062 0.638807779341935 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 34/3206 181/18639 0.187845303867403 1.09209251989536 0.313876865532348 0.639160604955875 GO:0004364 glutathione transferase activity 6/3206 27/18639 0.222222222222222 1.29195258889582 0.315141687165744 0.639160604955875 GO:0023026 MHC class II protein complex binding 6/3206 27/18639 0.222222222222222 1.29195258889582 0.315141687165744 0.639160604955875 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 6/3206 27/18639 0.222222222222222 1.29195258889582 0.315141687165744 0.639160604955875 GO:0004725 protein tyrosine phosphatase activity 19/3206 98/18639 0.193877551020408 1.12716271786319 0.321253749316049 0.65028566391586 GO:0120013 lipid transfer activity 13/3206 65/18639 0.2 1.16275733000624 0.321630486550977 0.65028566391586 GO:0030021 extracellular matrix structural constituent conferring compression resistance 5/3206 22/18639 0.227272727272727 1.32131514773436 0.324257106703188 0.650521997348811 GO:0034062 5'-3' RNA polymerase activity 5/3206 22/18639 0.227272727272727 1.32131514773436 0.324257106703188 0.650521997348811 GO:0050321 tau-protein kinase activity 5/3206 22/18639 0.227272727272727 1.32131514773436 0.324257106703188 0.650521997348811 GO:0097747 RNA polymerase activity 5/3206 22/18639 0.227272727272727 1.32131514773436 0.324257106703188 0.650521997348811 GO:0140035 ubiquitin-like protein reader activity 5/3206 22/18639 0.227272727272727 1.32131514773436 0.324257106703188 0.650521997348811 GO:0005506 iron ion binding 29/3206 154/18639 0.188311688311688 1.09480397955133 0.326423461092281 0.653855959158572 GO:0001222 transcription corepressor binding 10/3206 49/18639 0.204081632653061 1.18648707143494 0.329868786760501 0.659737573521002 GO:0033549 MAP kinase phosphatase activity 16/3206 82/18639 0.195121951219512 1.13439739512804 0.331620789471881 0.662219635062493 GO:0038191 neuropilin binding 4/3206 17/18639 0.235294117647059 1.36794980000734 0.333371501066995 0.664691485204347 GO:0016791 phosphatase activity 50/3206 273/18639 0.183150183150183 1.0647960897493 0.335446499412087 0.666706648162894 GO:0140416 transcription regulator inhibitor activity 7/3206 33/18639 0.212121212121212 1.23322747121874 0.336156688773676 0.666706648162894 GO:0019783 ubiquitin-like protein peptidase activity 24/3206 127/18639 0.188976377952756 1.09866834331298 0.34020361502754 0.666706648162894 GO:0003720 telomerase activity 3/3206 12/18639 0.25 1.4534466625078 0.341584270355063 0.666706648162894 GO:0016208 AMP binding 3/3206 12/18639 0.25 1.4534466625078 0.341584270355063 0.666706648162894 GO:0016801 hydrolase activity, acting on ether bonds 3/3206 12/18639 0.25 1.4534466625078 0.341584270355063 0.666706648162894 GO:0016803 ether hydrolase activity 3/3206 12/18639 0.25 1.4534466625078 0.341584270355063 0.666706648162894 GO:0016840 carbon-nitrogen lyase activity 3/3206 12/18639 0.25 1.4534466625078 0.341584270355063 0.666706648162894 GO:0034452 dynactin binding 3/3206 12/18639 0.25 1.4534466625078 0.341584270355063 0.666706648162894 GO:0035197 siRNA binding 3/3206 12/18639 0.25 1.4534466625078 0.341584270355063 0.666706648162894 GO:0035497 cAMP response element binding 3/3206 12/18639 0.25 1.4534466625078 0.341584270355063 0.666706648162894 GO:0043047 single-stranded telomeric DNA binding 3/3206 12/18639 0.25 1.4534466625078 0.341584270355063 0.666706648162894 GO:0045295 gamma-catenin binding 3/3206 12/18639 0.25 1.4534466625078 0.341584270355063 0.666706648162894 GO:0070008 serine-type exopeptidase activity 3/3206 12/18639 0.25 1.4534466625078 0.341584270355063 0.666706648162894 GO:0019789 SUMO transferase activity 6/3206 28/18639 0.214285714285714 1.24581142500668 0.34803942979012 0.677265917429423 GO:0046875 ephrin receptor binding 6/3206 28/18639 0.214285714285714 1.24581142500668 0.34803942979012 0.677265917429423 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 16/3206 83/18639 0.192771084337349 1.12072995663252 0.350496769823534 0.681025207932984 GO:0008514 organic anion transmembrane transporter activity 49/3206 269/18639 0.182156133828996 1.05901689907631 0.352751327192609 0.684379820421588 GO:0015605 organophosphate ester transmembrane transporter activity 10/3206 50/18639 0.2 1.16275733000624 0.354399695894832 0.686550083527209 GO:0061659 ubiquitin-like protein ligase activity 67/3206 372/18639 0.18010752688172 1.04710673535508 0.358819585521992 0.694074899755972 GO:0043274 phospholipase binding 5/3206 23/18639 0.217391304347826 1.26386666305026 0.361125421036926 0.696456169142642 GO:0140103 catalytic activity, acting on a glycoprotein 5/3206 23/18639 0.217391304347826 1.26386666305026 0.361125421036926 0.696456169142642 GO:0008013 beta-catenin binding 20/3206 106/18639 0.188679245283019 1.09694087736438 0.362478311924117 0.698026585815239 GO:0015078 proton transmembrane transporter activity 34/3206 185/18639 0.183783783783784 1.06847970865438 0.364176741303574 0.700256760726161 GO:0017018 myosin phosphatase activity 16/3206 84/18639 0.19047619047619 1.10738793333927 0.369575750198465 0.709585440381052 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 4/3206 18/18639 0.222222222222222 1.29195258889582 0.375760432213448 0.718267728832785 GO:0008409 5'-3' exonuclease activity 4/3206 18/18639 0.222222222222222 1.29195258889582 0.375760432213448 0.718267728832785 GO:0015172 acidic amino acid transmembrane transporter activity 4/3206 18/18639 0.222222222222222 1.29195258889582 0.375760432213448 0.718267728832785 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 8/3206 40/18639 0.2 1.16275733000624 0.381174308918264 0.723336317297229 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 6/3206 29/18639 0.206896551724138 1.20285241035128 0.381202704254635 0.723336317297229 GO:0010484 histone H3 acetyltransferase activity 6/3206 29/18639 0.206896551724138 1.20285241035128 0.381202704254635 0.723336317297229 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 6/3206 29/18639 0.206896551724138 1.20285241035128 0.381202704254635 0.723336317297229 GO:0097472 cyclin-dependent protein kinase activity 6/3206 29/18639 0.206896551724138 1.20285241035128 0.381202704254635 0.723336317297229 GO:0016798 hydrolase activity, acting on glycosyl bonds 24/3206 130/18639 0.184615384615385 1.0733144584673 0.386313743147617 0.73196288175338 GO:0003964 RNA-directed DNA polymerase activity 3/3206 13/18639 0.230769230769231 1.34164307308412 0.392469166246591 0.73502895875084 GO:0005172 vascular endothelial growth factor receptor binding 3/3206 13/18639 0.230769230769231 1.34164307308412 0.392469166246591 0.73502895875084 GO:0005338 nucleotide-sugar transmembrane transporter activity 3/3206 13/18639 0.230769230769231 1.34164307308412 0.392469166246591 0.73502895875084 GO:0008417 fucosyltransferase activity 3/3206 13/18639 0.230769230769231 1.34164307308412 0.392469166246591 0.73502895875084 GO:0035673 oligopeptide transmembrane transporter activity 3/3206 13/18639 0.230769230769231 1.34164307308412 0.392469166246591 0.73502895875084 GO:0046974 histone H3K9 methyltransferase activity 3/3206 13/18639 0.230769230769231 1.34164307308412 0.392469166246591 0.73502895875084 GO:0051011 microtubule minus-end binding 3/3206 13/18639 0.230769230769231 1.34164307308412 0.392469166246591 0.73502895875084 GO:0070700 BMP receptor binding 3/3206 13/18639 0.230769230769231 1.34164307308412 0.392469166246591 0.73502895875084 GO:0020037 heme binding 26/3206 142/18639 0.183098591549296 1.06449614718881 0.396446426661661 0.741406304406222 GO:0005315 phosphate transmembrane transporter activity 5/3206 24/18639 0.208333333333333 1.21120555208983 0.398081396953102 0.742321568994561 GO:0060229 lipase activator activity 5/3206 24/18639 0.208333333333333 1.21120555208983 0.398081396953102 0.742321568994561 GO:0046943 carboxylic acid transmembrane transporter activity 34/3206 188/18639 0.180851063829787 1.05142950053756 0.403008681676038 0.750429958982968 GO:0030159 signaling receptor complex adaptor activity 10/3206 52/18639 0.192307692307692 1.11803589423677 0.404080692833653 0.751346596717954 GO:0001727 lipid kinase activity 8/3206 41/18639 0.195121951219512 1.13439739512804 0.409372891896769 0.759008966950233 GO:0017080 sodium channel regulator activity 8/3206 41/18639 0.195121951219512 1.13439739512804 0.409372891896769 0.759008966950233 GO:0008106 alcohol dehydrogenase (NADP+) activity 6/3206 30/18639 0.2 1.16275733000624 0.414384541361585 0.766108938095026 GO:0015215 nucleotide transmembrane transporter activity 6/3206 30/18639 0.2 1.16275733000624 0.414384541361585 0.766108938095026 GO:0005342 organic acid transmembrane transporter activity 34/3206 189/18639 0.17989417989418 1.04586638148709 0.416086427410617 0.767100366655415 GO:0016918 retinal binding 4/3206 19/18639 0.210526315789474 1.22395508421709 0.417880292329261 0.767100366655415 GO:0034987 immunoglobulin receptor binding 4/3206 19/18639 0.210526315789474 1.22395508421709 0.417880292329261 0.767100366655415 GO:0046624 sphingolipid transporter activity 4/3206 19/18639 0.210526315789474 1.22395508421709 0.417880292329261 0.767100366655415 GO:0140036 ubiquitin-modified protein reader activity 4/3206 19/18639 0.210526315789474 1.22395508421709 0.417880292329261 0.767100366655415 GO:0005504 fatty acid binding 9/3206 47/18639 0.191489361702128 1.11327829468682 0.419944661968092 0.769799550085782 GO:0030971 receptor tyrosine kinase binding 15/3206 81/18639 0.185185185185185 1.07662715741318 0.421312319059046 0.771215770480966 GO:0033218 amide binding 44/3206 247/18639 0.178137651821862 1.03565430202985 0.424764505699511 0.776438363027597 GO:0044390 ubiquitin-like protein conjugating enzyme binding 7/3206 36/18639 0.194444444444444 1.13045851528384 0.427121627945286 0.779647365939564 GO:0004842 ubiquitin-protein transferase activity 79/3206 449/18639 0.175946547884187 1.02291569120816 0.431114177215917 0.785828373659392 GO:0004709 MAP kinase kinase kinase activity 5/3206 25/18639 0.2 1.16275733000624 0.434802712844926 0.790328633726542 GO:0005537 D-mannose binding 5/3206 25/18639 0.2 1.16275733000624 0.434802712844926 0.790328633726542 GO:0070888 E-box binding 11/3206 59/18639 0.186440677966102 1.08392632458209 0.436969217111006 0.791953585039184 GO:0004402 histone acetyltransferase activity 8/3206 42/18639 0.19047619047619 1.10738793333927 0.437529912722265 0.791953585039184 GO:0019894 kinesin binding 8/3206 42/18639 0.19047619047619 1.10738793333927 0.437529912722265 0.791953585039184 GO:0008494 translation activator activity 3/3206 14/18639 0.214285714285714 1.24581142500668 0.442264519474022 0.794972007265372 GO:0008559 ABC-type xenobiotic transporter activity 3/3206 14/18639 0.214285714285714 1.24581142500668 0.442264519474022 0.794972007265372 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 3/3206 14/18639 0.214285714285714 1.24581142500668 0.442264519474022 0.794972007265372 GO:0071933 Arp2/3 complex binding 3/3206 14/18639 0.214285714285714 1.24581142500668 0.442264519474022 0.794972007265372 GO:1901474 azole transmembrane transporter activity 3/3206 14/18639 0.214285714285714 1.24581142500668 0.442264519474022 0.794972007265372 GO:0005310 dicarboxylic acid transmembrane transporter activity 6/3206 31/18639 0.193548387096774 1.1252490290383 0.447355615227841 0.800791267037681 GO:0016878 acid-thiol ligase activity 6/3206 31/18639 0.193548387096774 1.1252490290383 0.447355615227841 0.800791267037681 GO:0070273 phosphatidylinositol-4-phosphate binding 6/3206 31/18639 0.193548387096774 1.1252490290383 0.447355615227841 0.800791267037681 GO:0061630 ubiquitin protein ligase activity 62/3206 353/18639 0.175637393767705 1.02111833513296 0.449801960903026 0.80398545136222 GO:0140299 molecular sensor activity 13/3206 71/18639 0.183098591549296 1.06449614718881 0.45038073895754 0.80398545136222 GO:0035091 phosphatidylinositol binding 50/3206 284/18639 0.176056338028169 1.02355398768155 0.452363229544923 0.80641368017912 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 10/3206 54/18639 0.185185185185185 1.07662715741318 0.45390153180545 0.808044485192119 GO:0030551 cyclic nucleotide binding 7/3206 37/18639 0.189189189189189 1.09990558243833 0.457292918968266 0.810964697139052 GO:0016004 phospholipase activator activity 4/3206 20/18639 0.2 1.16275733000624 0.459296363966099 0.810964697139052 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 4/3206 20/18639 0.2 1.16275733000624 0.459296363966099 0.810964697139052 GO:0052745 inositol phosphate phosphatase activity 4/3206 20/18639 0.2 1.16275733000624 0.459296363966099 0.810964697139052 GO:0140664 ATP-dependent DNA damage sensor activity 4/3206 20/18639 0.2 1.16275733000624 0.459296363966099 0.810964697139052 GO:0140939 histone H4 methyltransferase activity 4/3206 20/18639 0.2 1.16275733000624 0.459296363966099 0.810964697139052 GO:0008200 ion channel inhibitor activity 8/3206 43/18639 0.186046511627907 1.0816347255872 0.465507971357 0.818936770276984 GO:0008375 acetylglucosaminyltransferase activity 8/3206 43/18639 0.186046511627907 1.0816347255872 0.465507971357 0.818936770276984 GO:0031406 carboxylic acid binding 33/3206 187/18639 0.176470588235294 1.0259623500055 0.465707098529427 0.818936770276984 GO:0005160 transforming growth factor beta receptor binding 5/3206 26/18639 0.192307692307692 1.11803589423677 0.471000866426248 0.824888003903267 GO:0008157 protein phosphatase 1 binding 5/3206 26/18639 0.192307692307692 1.11803589423677 0.471000866426248 0.824888003903267 GO:0051139 metal cation:proton antiporter activity 5/3206 26/18639 0.192307692307692 1.11803589423677 0.471000866426248 0.824888003903267 GO:0000146 microfilament motor activity 7/3206 38/18639 0.184210526315789 1.07096069868996 0.487110993747248 0.845102970478638 GO:0004467 long-chain fatty acid-CoA ligase activity 3/3206 15/18639 0.2 1.16275733000624 0.490368390277728 0.845102970478638 GO:0005523 tropomyosin binding 3/3206 15/18639 0.2 1.16275733000624 0.490368390277728 0.845102970478638 GO:0010181 FMN binding 3/3206 15/18639 0.2 1.16275733000624 0.490368390277728 0.845102970478638 GO:0016846 carbon-sulfur lyase activity 3/3206 15/18639 0.2 1.16275733000624 0.490368390277728 0.845102970478638 GO:0031386 protein tag activity 3/3206 15/18639 0.2 1.16275733000624 0.490368390277728 0.845102970478638 GO:0042809 nuclear vitamin D receptor binding 3/3206 15/18639 0.2 1.16275733000624 0.490368390277728 0.845102970478638 GO:0045504 dynein heavy chain binding 3/3206 15/18639 0.2 1.16275733000624 0.490368390277728 0.845102970478638 GO:0050780 dopamine receptor binding 3/3206 15/18639 0.2 1.16275733000624 0.490368390277728 0.845102970478638 GO:0061578 K63-linked deubiquitinase activity 3/3206 15/18639 0.2 1.16275733000624 0.490368390277728 0.845102970478638 GO:0140161 monocarboxylate:sodium symporter activity 3/3206 15/18639 0.2 1.16275733000624 0.490368390277728 0.845102970478638 GO:0141047 molecular tag activity 3/3206 15/18639 0.2 1.16275733000624 0.490368390277728 0.845102970478638 GO:0043177 organic acid binding 33/3206 189/18639 0.174603174603175 1.015105605561 0.492376236605824 0.847436391289705 GO:0016248 channel inhibitor activity 8/3206 44/18639 0.181818181818182 1.05705211818749 0.493179191444473 0.847692615533206 GO:0004843 cysteine-type deubiquitinase activity 19/3206 108/18639 0.175925925925926 1.02279579954252 0.496692980128794 0.852601459929691 GO:0015174 basic amino acid transmembrane transporter activity 4/3206 21/18639 0.19047619047619 1.10738793333927 0.49964171494692 0.855397176448095 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 4/3206 21/18639 0.19047619047619 1.10738793333927 0.49964171494692 0.855397176448095 GO:0019902 phosphatase binding 33/3206 190/18639 0.173684210526316 1.0097629444791 0.505653926591663 0.857953120868818 GO:0004683 calcium/calmodulin-dependent protein kinase activity 5/3206 27/18639 0.185185185185185 1.07662715741318 0.506423407167271 0.857953120868818 GO:0016405 CoA-ligase activity 5/3206 27/18639 0.185185185185185 1.07662715741318 0.506423407167271 0.857953120868818 GO:0019956 chemokine binding 6/3206 33/18639 0.181818181818182 1.05705211818749 0.511851380033216 0.857953120868818 GO:0140311 protein sequestering activity 6/3206 33/18639 0.181818181818182 1.05705211818749 0.511851380033216 0.857953120868818 GO:0101005 deubiquitinase activity 20/3206 115/18639 0.173913043478261 1.01109333044021 0.516996023742786 0.857953120868818 GO:0048306 calcium-dependent protein binding 14/3206 80/18639 0.175 1.01741266375546 0.517878700642556 0.857953120868818 GO:0042605 peptide antigen binding 8/3206 45/18639 0.177777777777778 1.03356207111666 0.520426222585102 0.857953120868818 GO:0141110 transporter inhibitor activity 8/3206 45/18639 0.177777777777778 1.03356207111666 0.520426222585102 0.857953120868818 GO:0030695 GTPase regulator activity 84/3206 489/18639 0.171779141104294 0.998687277305972 0.524546312257873 0.857953120868818 GO:0030295 protein kinase activator activity 24/3206 139/18639 0.172661870503597 1.00381927770323 0.527049192336412 0.857953120868818 GO:0060589 nucleoside-triphosphatase regulator activity 84/3206 490/18639 0.171428571428571 0.996649140005347 0.532840168343302 0.857953120868818 GO:0004090 carbonyl reductase (NADPH) activity 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0005337 nucleoside transmembrane transporter activity 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0005381 iron ion transmembrane transporter activity 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0008239 dipeptidyl-peptidase activity 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0015187 glycine transmembrane transporter activity 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0015203 polyamine transmembrane transporter activity 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0015643 toxic substance binding 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0031434 mitogen-activated protein kinase kinase binding 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0032356 oxidized DNA binding 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0035374 chondroitin sulfate binding 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0043121 neurotrophin binding 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0043208 glycosphingolipid binding 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0043422 protein kinase B binding 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0045322 unmethylated CpG binding 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0070097 delta-catenin binding 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0140135 mechanosensitive monoatomic cation channel activity 2/3206 10/18639 0.2 1.16275733000624 0.533974306116401 0.857953120868818 GO:0004708 MAP kinase kinase activity 3/3206 16/18639 0.1875 1.09008499688085 0.536327065911151 0.857953120868818 GO:0015378 sodium:chloride symporter activity 3/3206 16/18639 0.1875 1.09008499688085 0.536327065911151 0.857953120868818 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 3/3206 16/18639 0.1875 1.09008499688085 0.536327065911151 0.857953120868818 GO:0031435 mitogen-activated protein kinase kinase kinase binding 3/3206 16/18639 0.1875 1.09008499688085 0.536327065911151 0.857953120868818 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 3/3206 16/18639 0.1875 1.09008499688085 0.536327065911151 0.857953120868818 GO:0004407 histone deacetylase activity 4/3206 22/18639 0.181818181818182 1.05705211818749 0.538616072334416 0.857953120868818 GO:0015377 chloride:monoatomic cation symporter activity 4/3206 22/18639 0.181818181818182 1.05705211818749 0.538616072334416 0.857953120868818 GO:0032931 histone H3K56 acetyltransferase activity 4/3206 22/18639 0.181818181818182 1.05705211818749 0.538616072334416 0.857953120868818 GO:0033558 protein lysine deacetylase activity 4/3206 22/18639 0.181818181818182 1.05705211818749 0.538616072334416 0.857953120868818 GO:0043992 histone H3K9 acetyltransferase activity 4/3206 22/18639 0.181818181818182 1.05705211818749 0.538616072334416 0.857953120868818 GO:0043993 histone H3K18 acetyltransferase activity 4/3206 22/18639 0.181818181818182 1.05705211818749 0.538616072334416 0.857953120868818 GO:0043994 histone H3K23 acetyltransferase activity 4/3206 22/18639 0.181818181818182 1.05705211818749 0.538616072334416 0.857953120868818 GO:0043999 histone H2AK5 acetyltransferase activity 4/3206 22/18639 0.181818181818182 1.05705211818749 0.538616072334416 0.857953120868818 GO:0044012 histone H2AK9 acetyltransferase activity 4/3206 22/18639 0.181818181818182 1.05705211818749 0.538616072334416 0.857953120868818 GO:0044014 histone H2BK5 acetyltransferase activity 4/3206 22/18639 0.181818181818182 1.05705211818749 0.538616072334416 0.857953120868818 GO:0044015 histone H2BK12 acetyltransferase activity 4/3206 22/18639 0.181818181818182 1.05705211818749 0.538616072334416 0.857953120868818 GO:0044016 histone H3K4 acetyltransferase activity 4/3206 22/18639 0.181818181818182 1.05705211818749 0.538616072334416 0.857953120868818 GO:0044017 histone H3K27 acetyltransferase activity 4/3206 22/18639 0.181818181818182 1.05705211818749 0.538616072334416 0.857953120868818 GO:0044018 histone H3K36 acetyltransferase activity 4/3206 22/18639 0.181818181818182 1.05705211818749 0.538616072334416 0.857953120868818 GO:0046972 histone H4K16 acetyltransferase activity 4/3206 22/18639 0.181818181818182 1.05705211818749 0.538616072334416 0.857953120868818 GO:0140908 histone H3K122 acetyltransferase activity 4/3206 22/18639 0.181818181818182 1.05705211818749 0.538616072334416 0.857953120868818 GO:0036408 histone H3K14 acetyltransferase activity 5/3206 28/18639 0.178571428571429 1.03817618750557 0.540854706597087 0.857953120868818 GO:0045499 chemorepellent activity 5/3206 28/18639 0.178571428571429 1.03817618750557 0.540854706597087 0.857953120868818 GO:0046966 nuclear thyroid hormone receptor binding 5/3206 28/18639 0.178571428571429 1.03817618750557 0.540854706597087 0.857953120868818 GO:0050698 proteoglycan sulfotransferase activity 5/3206 28/18639 0.178571428571429 1.03817618750557 0.540854706597087 0.857953120868818 GO:0051019 mitogen-activated protein kinase binding 5/3206 28/18639 0.178571428571429 1.03817618750557 0.540854706597087 0.857953120868818 GO:0141052 histone H3 demethylase activity 5/3206 28/18639 0.178571428571429 1.03817618750557 0.540854706597087 0.857953120868818 GO:0008376 acetylgalactosaminyltransferase activity 6/3206 34/18639 0.176470588235294 1.0259623500055 0.54302510755826 0.860342957696216 GO:0030276 clathrin binding 8/3206 46/18639 0.173913043478261 1.01109333044021 0.547142945176502 0.865808616543036 GO:0016782 transferase activity, transferring sulphur-containing groups 12/3206 70/18639 0.171428571428571 0.996649140005347 0.5545736278299 0.876496855692135 GO:0005154 epidermal growth factor receptor binding 6/3206 35/18639 0.171428571428571 0.996649140005347 0.573287390158955 0.898805977753064 GO:0051018 protein kinase A binding 9/3206 53/18639 0.169811320754717 0.987246789627938 0.57365452595398 0.898805977753064 GO:1901505 carbohydrate derivative transmembrane transporter activity 9/3206 53/18639 0.169811320754717 0.987246789627938 0.57365452595398 0.898805977753064 GO:0019209 kinase activator activity 25/3206 148/18639 0.168918918918919 0.982058555748512 0.573921300862848 0.898805977753064 GO:0005283 amino acid:sodium symporter activity 4/3206 23/18639 0.173913043478261 1.01109333044021 0.57598252523915 0.898805977753064 GO:0044013 histone H2B acetyltransferase activity 4/3206 23/18639 0.173913043478261 1.01109333044021 0.57598252523915 0.898805977753064 GO:0099186 structural constituent of postsynapse 4/3206 23/18639 0.173913043478261 1.01109333044021 0.57598252523915 0.898805977753064 GO:0030165 PDZ domain binding 14/3206 83/18639 0.168674698795181 0.980638712053454 0.577540998992162 0.898805977753064 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 3/3206 17/18639 0.176470588235294 1.0259623500055 0.579817544092041 0.898805977753064 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 3/3206 17/18639 0.176470588235294 1.0259623500055 0.579817544092041 0.898805977753064 GO:0008429 phosphatidylethanolamine binding 3/3206 17/18639 0.176470588235294 1.0259623500055 0.579817544092041 0.898805977753064 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 3/3206 17/18639 0.176470588235294 1.0259623500055 0.579817544092041 0.898805977753064 GO:0030169 low-density lipoprotein particle binding 3/3206 17/18639 0.176470588235294 1.0259623500055 0.579817544092041 0.898805977753064 GO:0031489 myosin V binding 3/3206 17/18639 0.176470588235294 1.0259623500055 0.579817544092041 0.898805977753064 GO:0004143 ATP-dependent diacylglycerol kinase activity 2/3206 11/18639 0.181818181818182 1.05705211818749 0.588107615072992 0.898805977753064 GO:0005225 volume-sensitive anion channel activity 2/3206 11/18639 0.181818181818182 1.05705211818749 0.588107615072992 0.898805977753064 GO:0008046 axon guidance receptor activity 2/3206 11/18639 0.181818181818182 1.05705211818749 0.588107615072992 0.898805977753064 GO:0008432 JUN kinase binding 2/3206 11/18639 0.181818181818182 1.05705211818749 0.588107615072992 0.898805977753064 GO:0010854 adenylate cyclase regulator activity 2/3206 11/18639 0.181818181818182 1.05705211818749 0.588107615072992 0.898805977753064 GO:0015217 ADP transmembrane transporter activity 2/3206 11/18639 0.181818181818182 1.05705211818749 0.588107615072992 0.898805977753064 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/3206 11/18639 0.181818181818182 1.05705211818749 0.588107615072992 0.898805977753064 GO:0019107 myristoyltransferase activity 2/3206 11/18639 0.181818181818182 1.05705211818749 0.588107615072992 0.898805977753064 GO:0019215 intermediate filament binding 2/3206 11/18639 0.181818181818182 1.05705211818749 0.588107615072992 0.898805977753064 GO:0032404 mismatch repair complex binding 2/3206 11/18639 0.181818181818182 1.05705211818749 0.588107615072992 0.898805977753064 GO:0034056 estrogen response element binding 2/3206 11/18639 0.181818181818182 1.05705211818749 0.588107615072992 0.898805977753064 GO:0042608 T cell receptor binding 2/3206 11/18639 0.181818181818182 1.05705211818749 0.588107615072992 0.898805977753064 GO:0047676 arachidonate-CoA ligase activity 2/3206 11/18639 0.181818181818182 1.05705211818749 0.588107615072992 0.898805977753064 GO:0140537 transcription regulator activator activity 2/3206 11/18639 0.181818181818182 1.05705211818749 0.588107615072992 0.898805977753064 GO:1901981 phosphatidylinositol phosphate binding 31/3206 185/18639 0.167567567567568 0.974202087302524 0.594346962167079 0.907271687831018 GO:0019199 transmembrane receptor protein kinase activity 13/3206 78/18639 0.166666666666667 0.968964441671865 0.59658114080543 0.909508602964418 GO:0005496 steroid binding 18/3206 108/18639 0.166666666666667 0.968964441671865 0.598378398842817 0.909508602964418 GO:0030246 carbohydrate binding 47/3206 280/18639 0.167857142857143 0.975885616255236 0.598384380153761 0.909508602964418 GO:0032266 phosphatidylinositol-3-phosphate binding 8/3206 48/18639 0.166666666666667 0.968964441671865 0.598619474019019 0.909508602964418 GO:0042578 phosphoric ester hydrolase activity 61/3206 363/18639 0.168044077134986 0.976972412264195 0.601936200536705 0.910146020090174 GO:0004033 aldo-keto reductase (NADPH) activity 6/3206 36/18639 0.166666666666667 0.968964441671865 0.602520542601688 0.910146020090174 GO:0005484 SNAP receptor activity 6/3206 36/18639 0.166666666666667 0.968964441671865 0.602520542601688 0.910146020090174 GO:0001965 G-protein alpha-subunit binding 5/3206 30/18639 0.166666666666667 0.968964441671865 0.606061740229799 0.910146020090174 GO:0032452 histone demethylase activity 5/3206 30/18639 0.166666666666667 0.968964441671865 0.606061740229799 0.910146020090174 GO:0043995 histone H4K5 acetyltransferase activity 5/3206 30/18639 0.166666666666667 0.968964441671865 0.606061740229799 0.910146020090174 GO:0043996 histone H4K8 acetyltransferase activity 5/3206 30/18639 0.166666666666667 0.968964441671865 0.606061740229799 0.910146020090174 GO:0043997 histone H4K12 acetyltransferase activity 5/3206 30/18639 0.166666666666667 0.968964441671865 0.606061740229799 0.910146020090174 GO:0070566 adenylyltransferase activity 5/3206 30/18639 0.166666666666667 0.968964441671865 0.606061740229799 0.910146020090174 GO:0098918 structural constituent of synapse 5/3206 30/18639 0.166666666666667 0.968964441671865 0.606061740229799 0.910146020090174 GO:0030215 semaphorin receptor binding 4/3206 24/18639 0.166666666666667 0.968964441671865 0.61156275089636 0.912065966814364 GO:0030552 cAMP binding 4/3206 24/18639 0.166666666666667 0.968964441671865 0.61156275089636 0.912065966814364 GO:0035035 histone acetyltransferase binding 4/3206 24/18639 0.166666666666667 0.968964441671865 0.61156275089636 0.912065966814364 GO:0043998 histone H2A acetyltransferase activity 4/3206 24/18639 0.166666666666667 0.968964441671865 0.61156275089636 0.912065966814364 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 4/3206 24/18639 0.166666666666667 0.968964441671865 0.61156275089636 0.912065966814364 GO:0140612 DNA damage sensor activity 4/3206 24/18639 0.166666666666667 0.968964441671865 0.61156275089636 0.912065966814364 GO:0016836 hydro-lyase activity 10/3206 61/18639 0.163934426229508 0.953079778693638 0.619124897898979 0.91609924890913 GO:0008234 cysteine-type peptidase activity 31/3206 187/18639 0.165775401069519 0.963782813641535 0.619908601893779 0.91609924890913 GO:0004706 JUN kinase kinase kinase activity 3/3206 18/18639 0.166666666666667 0.968964441671865 0.62062896646776 0.91609924890913 GO:0015373 monoatomic anion:sodium symporter activity 3/3206 18/18639 0.166666666666667 0.968964441671865 0.62062896646776 0.91609924890913 GO:0016854 racemase and epimerase activity 3/3206 18/18639 0.166666666666667 0.968964441671865 0.62062896646776 0.91609924890913 GO:0031690 adrenergic receptor binding 3/3206 18/18639 0.166666666666667 0.968964441671865 0.62062896646776 0.91609924890913 GO:0050811 GABA receptor binding 3/3206 18/18639 0.166666666666667 0.968964441671865 0.62062896646776 0.91609924890913 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 3/3206 18/18639 0.166666666666667 0.968964441671865 0.62062896646776 0.91609924890913 GO:1990381 ubiquitin-specific protease binding 3/3206 18/18639 0.166666666666667 0.968964441671865 0.62062896646776 0.91609924890913 GO:0019213 deacetylase activity 6/3206 37/18639 0.162162162162162 0.942776213518572 0.630629114917835 0.925068667508943 GO:0023023 MHC protein complex binding 6/3206 37/18639 0.162162162162162 0.942776213518572 0.630629114917835 0.925068667508943 GO:0017147 Wnt-protein binding 5/3206 31/18639 0.161290322580645 0.937707524198579 0.636582148884023 0.925068667508943 GO:0047499 calcium-independent phospholipase A2 activity 5/3206 31/18639 0.161290322580645 0.937707524198579 0.636582148884023 0.925068667508943 GO:0070325 lipoprotein particle receptor binding 5/3206 31/18639 0.161290322580645 0.937707524198579 0.636582148884023 0.925068667508943 GO:0140457 protein demethylase activity 5/3206 31/18639 0.161290322580645 0.937707524198579 0.636582148884023 0.925068667508943 GO:0004000 adenosine deaminase activity 2/3206 12/18639 0.166666666666667 0.968964441671865 0.637412284016578 0.925068667508943 GO:0005078 MAP-kinase scaffold activity 2/3206 12/18639 0.166666666666667 0.968964441671865 0.637412284016578 0.925068667508943 GO:0008179 adenylate cyclase binding 2/3206 12/18639 0.166666666666667 0.968964441671865 0.637412284016578 0.925068667508943 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 2/3206 12/18639 0.166666666666667 0.968964441671865 0.637412284016578 0.925068667508943 GO:0008603 cAMP-dependent protein kinase regulator activity 2/3206 12/18639 0.166666666666667 0.968964441671865 0.637412284016578 0.925068667508943 GO:0010853 cyclase activator activity 2/3206 12/18639 0.166666666666667 0.968964441671865 0.637412284016578 0.925068667508943 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 2/3206 12/18639 0.166666666666667 0.968964441671865 0.637412284016578 0.925068667508943 GO:0097371 MDM2/MDM4 family protein binding 2/3206 12/18639 0.166666666666667 0.968964441671865 0.637412284016578 0.925068667508943 GO:1990817 poly(A) RNA polymerase activity 2/3206 12/18639 0.166666666666667 0.968964441671865 0.637412284016578 0.925068667508943 GO:0140223 general transcription initiation factor activity 11/3206 68/18639 0.161764705882353 0.940465487505046 0.638395108685784 0.925458681047848 GO:0008483 transaminase activity 4/3206 25/18639 0.16 0.930205864004991 0.645231329572823 0.929281694337916 GO:0015296 monoatomic anion:monoatomic cation symporter activity 4/3206 25/18639 0.16 0.930205864004991 0.645231329572823 0.929281694337916 GO:0015645 fatty acid ligase activity 4/3206 25/18639 0.16 0.930205864004991 0.645231329572823 0.929281694337916 GO:0120020 cholesterol transfer activity 4/3206 25/18639 0.16 0.930205864004991 0.645231329572823 0.929281694337916 GO:0120515 fatty acid-CoA ligase activity 4/3206 25/18639 0.16 0.930205864004991 0.645231329572823 0.929281694337916 GO:0005516 calmodulin binding 34/3206 207/18639 0.164251207729469 0.954921478749085 0.645334509956886 0.929281694337916 GO:0005007 fibroblast growth factor receptor activity 8/3206 50/18639 0.16 0.930205864004991 0.646994818587272 0.930139305669067 GO:1902936 phosphatidylinositol bisphosphate binding 18/3206 111/18639 0.162162162162162 0.942776213518572 0.647365473544366 0.930139305669067 GO:0001223 transcription coactivator binding 7/3206 44/18639 0.159090909090909 0.924920603414053 0.651559480303492 0.934094122205006 GO:0030547 signaling receptor inhibitor activity 7/3206 44/18639 0.159090909090909 0.924920603414053 0.651559480303492 0.934094122205006 GO:0005109 frizzled binding 6/3206 38/18639 0.157894736842105 0.91796631316282 0.65753876263732 0.935968276708193 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 3/3206 19/18639 0.157894736842105 0.91796631316282 0.658644342868728 0.935968276708193 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 3/3206 19/18639 0.157894736842105 0.91796631316282 0.658644342868728 0.935968276708193 GO:0005346 purine ribonucleotide transmembrane transporter activity 3/3206 19/18639 0.157894736842105 0.91796631316282 0.658644342868728 0.935968276708193 GO:0008381 mechanosensitive monoatomic ion channel activity 3/3206 19/18639 0.157894736842105 0.91796631316282 0.658644342868728 0.935968276708193 GO:0043395 heparan sulfate proteoglycan binding 3/3206 19/18639 0.157894736842105 0.91796631316282 0.658644342868728 0.935968276708193 GO:0050145 nucleoside monophosphate kinase activity 3/3206 19/18639 0.157894736842105 0.91796631316282 0.658644342868728 0.935968276708193 GO:0120227 acyl-CoA binding 3/3206 19/18639 0.157894736842105 0.91796631316282 0.658644342868728 0.935968276708193 GO:0015106 bicarbonate transmembrane transporter activity 5/3206 32/18639 0.15625 0.908404164067374 0.665596085582304 0.94274593105428 GO:0047498 calcium-dependent phospholipase A2 activity 5/3206 32/18639 0.15625 0.908404164067374 0.665596085582304 0.94274593105428 GO:0120015 sterol transfer activity 5/3206 32/18639 0.15625 0.908404164067374 0.665596085582304 0.94274593105428 GO:1901681 sulfur compound binding 45/3206 275/18639 0.163636363636364 0.95134690636874 0.668990350102624 0.946519097961791 GO:0005030 neurotrophin receptor activity 8/3206 51/18639 0.156862745098039 0.911966533338226 0.669878325493106 0.946741886411194 GO:0017022 myosin binding 12/3206 76/18639 0.157894736842105 0.91796631316282 0.674505184660046 0.949305935182126 GO:0015216 purine nucleotide transmembrane transporter activity 4/3206 26/18639 0.153846153846154 0.894428715389414 0.676909595599473 0.949305935182126 GO:0034237 protein kinase A regulatory subunit binding 4/3206 26/18639 0.153846153846154 0.894428715389414 0.676909595599473 0.949305935182126 GO:0050750 low-density lipoprotein particle receptor binding 4/3206 26/18639 0.153846153846154 0.894428715389414 0.676909595599473 0.949305935182126 GO:0097602 cullin family protein binding 4/3206 26/18639 0.153846153846154 0.894428715389414 0.676909595599473 0.949305935182126 GO:0008028 monocarboxylic acid transmembrane transporter activity 11/3206 70/18639 0.157142857142857 0.913595045004901 0.677737963214373 0.949305935182126 GO:0002161 aminoacyl-tRNA editing activity 2/3206 13/18639 0.153846153846154 0.894428715389414 0.681947396338394 0.949305935182126 GO:0004535 poly(A)-specific ribonuclease activity 2/3206 13/18639 0.153846153846154 0.894428715389414 0.681947396338394 0.949305935182126 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/3206 13/18639 0.153846153846154 0.894428715389414 0.681947396338394 0.949305935182126 GO:0008035 high-density lipoprotein particle binding 2/3206 13/18639 0.153846153846154 0.894428715389414 0.681947396338394 0.949305935182126 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 2/3206 13/18639 0.153846153846154 0.894428715389414 0.681947396338394 0.949305935182126 GO:0031432 titin binding 2/3206 13/18639 0.153846153846154 0.894428715389414 0.681947396338394 0.949305935182126 GO:0039706 co-receptor binding 2/3206 13/18639 0.153846153846154 0.894428715389414 0.681947396338394 0.949305935182126 GO:0045159 myosin II binding 2/3206 13/18639 0.153846153846154 0.894428715389414 0.681947396338394 0.949305935182126 GO:0019955 cytokine binding 23/3206 144/18639 0.159722222222222 0.928590923268871 0.686022244388914 0.953953678892738 GO:0005096 GTPase activator activity 44/3206 271/18639 0.162361623616236 0.943935839857463 0.68855672792787 0.956451789276012 GO:0071889 14-3-3 protein binding 5/3206 33/18639 0.151515151515152 0.880876765156241 0.693050497287498 0.961663216792931 GO:0016505 peptidase activator activity involved in apoptotic process 3/3206 20/18639 0.15 0.872067997504679 0.693823397969192 0.961706014725212 GO:0038024 cargo receptor activity 10/3206 65/18639 0.153846153846154 0.894428715389414 0.700972382174513 0.970577144549326 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 4/3206 27/18639 0.148148148148148 0.861301725930547 0.706559367500726 0.977268879702178 GO:0032451 demethylase activity 6/3206 40/18639 0.15 0.872067997504679 0.707560815694868 0.977610679254317 GO:0005003 ephrin receptor activity 8/3206 53/18639 0.150943396226415 0.877552701891501 0.712849594699733 0.982747192287041 GO:0005005 transmembrane-ephrin receptor activity 8/3206 53/18639 0.150943396226415 0.877552701891501 0.712849594699733 0.982747192287041 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 14/3206 91/18639 0.153846153846154 0.894428715389414 0.718808232245349 0.982747192287041 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 5/3206 34/18639 0.147058823529412 0.854968625004587 0.718916943792539 0.982747192287041 GO:0004065 arylsulfatase activity 2/3206 14/18639 0.142857142857143 0.830540950004456 0.721894542482456 0.982747192287041 GO:0005313 L-glutamate transmembrane transporter activity 2/3206 14/18639 0.142857142857143 0.830540950004456 0.721894542482456 0.982747192287041 GO:0005347 ATP transmembrane transporter activity 2/3206 14/18639 0.142857142857143 0.830540950004456 0.721894542482456 0.982747192287041 GO:0008392 arachidonate epoxygenase activity 2/3206 14/18639 0.142857142857143 0.830540950004456 0.721894542482456 0.982747192287041 GO:0015926 glucosidase activity 2/3206 14/18639 0.142857142857143 0.830540950004456 0.721894542482456 0.982747192287041 GO:0030983 mismatched DNA binding 2/3206 14/18639 0.142857142857143 0.830540950004456 0.721894542482456 0.982747192287041 GO:0032036 myosin heavy chain binding 2/3206 14/18639 0.142857142857143 0.830540950004456 0.721894542482456 0.982747192287041 GO:0034236 protein kinase A catalytic subunit binding 2/3206 14/18639 0.142857142857143 0.830540950004456 0.721894542482456 0.982747192287041 GO:0046030 inositol trisphosphate phosphatase activity 2/3206 14/18639 0.142857142857143 0.830540950004456 0.721894542482456 0.982747192287041 GO:0061665 SUMO ligase activity 2/3206 14/18639 0.142857142857143 0.830540950004456 0.721894542482456 0.982747192287041 GO:0015291 secondary active transmembrane transporter activity 46/3206 287/18639 0.160278745644599 0.931826431712316 0.725290756793066 0.985353116837372 GO:0004714 transmembrane receptor protein tyrosine kinase activity 9/3206 60/18639 0.15 0.872067997504679 0.725668303078391 0.985353116837372 GO:0001846 opsonin binding 3/3206 21/18639 0.142857142857143 0.830540950004456 0.726187011806237 0.985353116837372 GO:0033293 monocarboxylic acid binding 12/3206 79/18639 0.151898734177215 0.88310683291613 0.72684998433374 0.985353116837372 GO:0004812 aminoacyl-tRNA ligase activity 6/3206 41/18639 0.146341463414634 0.850798046346028 0.7306165328342 0.986332319326169 GO:0016875 ligase activity, forming carbon-oxygen bonds 6/3206 41/18639 0.146341463414634 0.850798046346028 0.7306165328342 0.986332319326169 GO:0042287 MHC protein binding 6/3206 41/18639 0.146341463414634 0.850798046346028 0.7306165328342 0.986332319326169 GO:0140828 metal cation:monoatomic cation antiporter activity 6/3206 41/18639 0.146341463414634 0.850798046346028 0.7306165328342 0.986332319326169 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 10/3206 67/18639 0.149253731343284 0.867729350750924 0.737461630012442 0.994537224241545 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 20/3206 130/18639 0.153846153846154 0.894428715389414 0.743066624243583 0.997686531213082 GO:0004623 phospholipase A2 activity 5/3206 35/18639 0.142857142857143 0.830540950004456 0.743188536064803 0.997686531213082 GO:0005343 organic acid:sodium symporter activity 5/3206 35/18639 0.142857142857143 0.830540950004456 0.743188536064803 0.997686531213082 GO:0016229 steroid dehydrogenase activity 5/3206 35/18639 0.142857142857143 0.830540950004456 0.743188536064803 0.997686531213082 GO:0019905 syntaxin binding 9/3206 61/18639 0.147540983606557 0.857771800824274 0.744108507820981 0.997686531213082 GO:0042056 chemoattractant activity 6/3206 42/18639 0.142857142857143 0.830540950004456 0.752356458920889 0.997686531213082 GO:0000149 SNARE binding 16/3206 106/18639 0.150943396226415 0.877552701891501 0.755176249642011 0.997686531213082 GO:0004865 protein serine/threonine phosphatase inhibitor activity 2/3206 15/18639 0.133333333333333 0.775171553337492 0.757513950513953 0.997686531213082 GO:0005041 low-density lipoprotein particle receptor activity 2/3206 15/18639 0.133333333333333 0.775171553337492 0.757513950513953 0.997686531213082 GO:0008242 omega peptidase activity 2/3206 15/18639 0.133333333333333 0.775171553337492 0.757513950513953 0.997686531213082 GO:0015929 hexosaminidase activity 2/3206 15/18639 0.133333333333333 0.775171553337492 0.757513950513953 0.997686531213082 GO:0033130 acetylcholine receptor binding 2/3206 15/18639 0.133333333333333 0.775171553337492 0.757513950513953 0.997686531213082 GO:0048531 beta-1,3-galactosyltransferase activity 2/3206 15/18639 0.133333333333333 0.775171553337492 0.757513950513953 0.997686531213082 GO:0120283 protein serine/threonine kinase binding 2/3206 15/18639 0.133333333333333 0.775171553337492 0.757513950513953 0.997686531213082 GO:0005085 guanyl-nucleotide exchange factor activity 36/3206 230/18639 0.156521739130435 0.909983997396187 0.759493460084696 0.997686531213082 GO:0003785 actin monomer binding 4/3206 29/18639 0.137931034482759 0.801901606900854 0.759786614275263 0.997686531213082 GO:0005416 amino acid:monoatomic cation symporter activity 4/3206 29/18639 0.137931034482759 0.801901606900854 0.759786614275263 0.997686531213082 GO:0005004 GPI-linked ephrin receptor activity 7/3206 49/18639 0.142857142857143 0.830540950004456 0.76135183593344 0.997686531213082 GO:0005008 hepatocyte growth factor receptor activity 7/3206 49/18639 0.142857142857143 0.830540950004456 0.76135183593344 0.997686531213082 GO:0005009 insulin receptor activity 7/3206 49/18639 0.142857142857143 0.830540950004456 0.76135183593344 0.997686531213082 GO:0005011 macrophage colony-stimulating factor receptor activity 7/3206 49/18639 0.142857142857143 0.830540950004456 0.76135183593344 0.997686531213082 GO:0005018 platelet-derived growth factor alpha-receptor activity 7/3206 49/18639 0.142857142857143 0.830540950004456 0.76135183593344 0.997686531213082 GO:0005020 stem cell factor receptor activity 7/3206 49/18639 0.142857142857143 0.830540950004456 0.76135183593344 0.997686531213082 GO:0008288 boss receptor activity 7/3206 49/18639 0.142857142857143 0.830540950004456 0.76135183593344 0.997686531213082 GO:0016763 pentosyltransferase activity 7/3206 49/18639 0.142857142857143 0.830540950004456 0.76135183593344 0.997686531213082 GO:0036332 placental growth factor receptor activity 7/3206 49/18639 0.142857142857143 0.830540950004456 0.76135183593344 0.997686531213082 GO:0038062 protein tyrosine kinase collagen receptor activity 7/3206 49/18639 0.142857142857143 0.830540950004456 0.76135183593344 0.997686531213082 GO:0060175 brain-derived neurotrophic factor receptor activity 7/3206 49/18639 0.142857142857143 0.830540950004456 0.76135183593344 0.997686531213082 GO:0004869 cysteine-type endopeptidase inhibitor activity 5/3206 36/18639 0.138888888888889 0.807470368059888 0.765876922107241 0.999999999999998 GO:0045505 dynein intermediate chain binding 5/3206 36/18639 0.138888888888889 0.807470368059888 0.765876922107241 0.999999999999998 GO:0140767 enzyme-substrate adaptor activity 21/3206 139/18639 0.151079136690647 0.878341867990324 0.776055577351365 0.999999999999998 GO:0005006 epidermal growth factor receptor activity 7/3206 50/18639 0.14 0.813930131004367 0.779968094571188 0.999999999999998 GO:0005017 platelet-derived growth factor receptor activity 7/3206 50/18639 0.14 0.813930131004367 0.779968094571188 0.999999999999998 GO:0005019 platelet-derived growth factor beta-receptor activity 7/3206 50/18639 0.14 0.813930131004367 0.779968094571188 0.999999999999998 GO:0000295 adenine nucleotide transmembrane transporter activity 3/3206 23/18639 0.130434782608696 0.758319997830155 0.7827766185375 0.999999999999998 GO:0005158 insulin receptor binding 3/3206 23/18639 0.130434782608696 0.758319997830155 0.7827766185375 0.999999999999998 GO:0005212 structural constituent of eye lens 3/3206 23/18639 0.130434782608696 0.758319997830155 0.7827766185375 0.999999999999998 GO:0016493 C-C chemokine receptor activity 3/3206 23/18639 0.130434782608696 0.758319997830155 0.7827766185375 0.999999999999998 GO:0031681 G-protein beta-subunit binding 3/3206 23/18639 0.130434782608696 0.758319997830155 0.7827766185375 0.999999999999998 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 3/3206 23/18639 0.130434782608696 0.758319997830155 0.7827766185375 0.999999999999998 GO:0031624 ubiquitin conjugating enzyme binding 4/3206 30/18639 0.133333333333333 0.775171553337492 0.783436594897642 0.999999999999998 GO:0033612 receptor serine/threonine kinase binding 4/3206 30/18639 0.133333333333333 0.775171553337492 0.783436594897642 0.999999999999998 GO:0048019 receptor antagonist activity 4/3206 30/18639 0.133333333333333 0.775171553337492 0.783436594897642 0.999999999999998 GO:0043394 proteoglycan binding 5/3206 37/18639 0.135135135135135 0.78564684459881 0.787009391980586 0.999999999999998 GO:0000062 fatty-acyl-CoA binding 2/3206 16/18639 0.125 0.726723331253899 0.789112076885782 0.999999999999998 GO:0005149 interleukin-1 receptor binding 2/3206 16/18639 0.125 0.726723331253899 0.789112076885782 0.999999999999998 GO:0008391 arachidonate monooxygenase activity 2/3206 16/18639 0.125 0.726723331253899 0.789112076885782 0.999999999999998 GO:0016722 oxidoreductase activity, acting on metal ions 2/3206 16/18639 0.125 0.726723331253899 0.789112076885782 0.999999999999998 GO:0055102 lipase inhibitor activity 2/3206 16/18639 0.125 0.726723331253899 0.789112076885782 0.999999999999998 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 2/3206 16/18639 0.125 0.726723331253899 0.789112076885782 0.999999999999998 GO:0005010 insulin-like growth factor receptor activity 7/3206 51/18639 0.137254901960784 0.797970716670948 0.797482376015429 0.999999999999998 GO:0005021 vascular endothelial growth factor receptor activity 7/3206 51/18639 0.137254901960784 0.797970716670948 0.797482376015429 0.999999999999998 GO:0016597 amino acid binding 7/3206 51/18639 0.137254901960784 0.797970716670948 0.797482376015429 0.999999999999998 GO:0005501 retinoid binding 5/3206 38/18639 0.131578947368421 0.764971927635683 0.806626154002293 0.999999999999998 GO:0019840 isoprenoid binding 5/3206 38/18639 0.131578947368421 0.764971927635683 0.806626154002293 0.999999999999998 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/3206 24/18639 0.125 0.726723331253899 0.807235742486234 0.999999999999998 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/3206 24/18639 0.125 0.726723331253899 0.807235742486234 0.999999999999998 GO:0004622 lysophospholipase activity 3/3206 24/18639 0.125 0.726723331253899 0.807235742486234 0.999999999999998 GO:0015295 solute:proton symporter activity 3/3206 24/18639 0.125 0.726723331253899 0.807235742486234 0.999999999999998 GO:0019957 C-C chemokine binding 3/3206 24/18639 0.125 0.726723331253899 0.807235742486234 0.999999999999998 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 7/3206 52/18639 0.134615384615385 0.782625125965737 0.813915787217896 0.999999999999998 GO:0008484 sulfuric ester hydrolase activity 2/3206 17/18639 0.117647058823529 0.68397490000367 0.817018014591614 0.999999999999998 GO:0008569 minus-end-directed microtubule motor activity 2/3206 17/18639 0.117647058823529 0.68397490000367 0.817018014591614 0.999999999999998 GO:0016805 dipeptidase activity 2/3206 17/18639 0.117647058823529 0.68397490000367 0.817018014591614 0.999999999999998 GO:0036041 long-chain fatty acid binding 2/3206 17/18639 0.117647058823529 0.68397490000367 0.817018014591614 0.999999999999998 GO:0070492 oligosaccharide binding 2/3206 17/18639 0.117647058823529 0.68397490000367 0.817018014591614 0.999999999999998 GO:1901567 fatty acid derivative binding 2/3206 17/18639 0.117647058823529 0.68397490000367 0.817018014591614 0.999999999999998 GO:0004879 nuclear receptor activity 8/3206 59/18639 0.135593220338983 0.788310054241517 0.818513984355516 0.999999999999998 GO:0015459 potassium channel regulator activity 8/3206 59/18639 0.135593220338983 0.788310054241517 0.818513984355516 0.999999999999998 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/3206 32/18639 0.125 0.726723331253899 0.825135198198965 0.999999999999998 GO:0071813 lipoprotein particle binding 4/3206 32/18639 0.125 0.726723331253899 0.825135198198965 0.999999999999998 GO:0071814 protein-lipid complex binding 4/3206 32/18639 0.125 0.726723331253899 0.825135198198965 0.999999999999998 GO:0005246 calcium channel regulator activity 7/3206 53/18639 0.132075471698113 0.767858614155063 0.829295425209791 0.999999999999998 GO:0016251 RNA polymerase II general transcription initiation factor activity 7/3206 53/18639 0.132075471698113 0.767858614155063 0.829295425209791 0.999999999999998 GO:0017046 peptide hormone binding 7/3206 53/18639 0.132075471698113 0.767858614155063 0.829295425209791 0.999999999999998 GO:0038064 collagen receptor activity 7/3206 53/18639 0.132075471698113 0.767858614155063 0.829295425209791 0.999999999999998 GO:0061134 peptidase regulator activity 34/3206 226/18639 0.150442477876106 0.874640469473719 0.829325363828312 0.999999999999998 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 3/3206 25/18639 0.12 0.697654398003743 0.829327253338063 0.999999999999998 GO:0098531 ligand-modulated transcription factor activity 8/3206 60/18639 0.133333333333333 0.775171553337492 0.832797935321227 0.999999999999998 GO:0016500 protein-hormone receptor activity 9/3206 67/18639 0.134328358208955 0.780956415675832 0.836685225089653 0.999999999999998 GO:0070851 growth factor receptor binding 20/3206 139/18639 0.143884892086331 0.836516064752689 0.840164784020348 0.999999999999998 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/3206 18/18639 0.111111111111111 0.64597629444791 0.841566645607096 0.999999999999998 GO:0030228 lipoprotein particle receptor activity 2/3206 18/18639 0.111111111111111 0.64597629444791 0.841566645607096 0.999999999999998 GO:0034185 apolipoprotein binding 2/3206 18/18639 0.111111111111111 0.64597629444791 0.841566645607096 0.999999999999998 GO:0035615 clathrin adaptor activity 2/3206 18/18639 0.111111111111111 0.64597629444791 0.841566645607096 0.999999999999998 GO:0099602 neurotransmitter receptor regulator activity 2/3206 18/18639 0.111111111111111 0.64597629444791 0.841566645607096 0.999999999999998 GO:0042562 hormone binding 13/3206 94/18639 0.138297872340426 0.804034323940484 0.84296940755262 0.999999999999998 GO:0004382 GDP phosphatase activity 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0004955 prostaglandin receptor activity 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0005031 tumor necrosis factor receptor activity 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0005131 growth hormone receptor binding 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0005345 purine nucleobase transmembrane transporter activity 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0008140 cAMP response element binding protein binding 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0008401 retinoic acid 4-hydroxylase activity 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0015279 store-operated calcium channel activity 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0019911 structural constituent of myelin sheath 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0032052 bile acid binding 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0035256 G protein-coupled glutamate receptor binding 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0043295 glutathione binding 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0050308 sugar-phosphatase activity 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0141109 transporter activator activity 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:1905394 retromer complex binding 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:1990763 arrestin family protein binding 1/3206 10/18639 0.1 0.581378665003119 0.84862310878484 0.999999999999998 GO:0001637 G protein-coupled chemoattractant receptor activity 3/3206 26/18639 0.115384615384615 0.670821536542061 0.849207817390922 0.999999999999998 GO:0004112 cyclic-nucleotide phosphodiesterase activity 3/3206 26/18639 0.115384615384615 0.670821536542061 0.849207817390922 0.999999999999998 GO:0004950 chemokine receptor activity 3/3206 26/18639 0.115384615384615 0.670821536542061 0.849207817390922 0.999999999999998 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/3206 26/18639 0.115384615384615 0.670821536542061 0.849207817390922 0.999999999999998 GO:0001530 lipopolysaccharide binding 5/3206 41/18639 0.121951219512195 0.708998371955023 0.856926793802722 0.999999999999998 GO:0052866 phosphatidylinositol phosphate phosphatase activity 4/3206 34/18639 0.117647058823529 0.68397490000367 0.859945355480694 0.999999999999998 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 17/3206 122/18639 0.139344262295082 0.810117811889592 0.861091981997824 0.999999999999998 GO:0003730 mRNA 3'-UTR binding 39/3206 262/18639 0.148854961832061 0.865410989890139 0.861289772013288 0.999999999999998 GO:0030506 ankyrin binding 2/3206 19/18639 0.105263157894737 0.611977542108546 0.863086916517492 0.999999999999998 GO:0070003 threonine-type peptidase activity 2/3206 19/18639 0.105263157894737 0.611977542108546 0.863086916517492 0.999999999999998 GO:1990380 K48-linked deubiquitinase activity 2/3206 19/18639 0.105263157894737 0.611977542108546 0.863086916517492 0.999999999999998 GO:0005044 scavenger receptor activity 3/3206 27/18639 0.111111111111111 0.64597629444791 0.867038873627197 0.999999999999998 GO:0016247 channel regulator activity 24/3206 168/18639 0.142857142857143 0.830540950004456 0.867497752436131 0.999999999999998 GO:0170055 lipid transmembrane transporter activity 7/3206 56/18639 0.125 0.726723331253899 0.869451758452474 0.999999999999998 GO:0003953 NAD+ nucleosidase activity 1/3206 11/18639 0.0909090909090909 0.528526059093745 0.874674658156025 0.999999999999998 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/3206 11/18639 0.0909090909090909 0.528526059093745 0.874674658156025 0.999999999999998 GO:0004954 prostanoid receptor activity 1/3206 11/18639 0.0909090909090909 0.528526059093745 0.874674658156025 0.999999999999998 GO:0008199 ferric iron binding 1/3206 11/18639 0.0909090909090909 0.528526059093745 0.874674658156025 0.999999999999998 GO:0008271 secondary active sulfate transmembrane transporter activity 1/3206 11/18639 0.0909090909090909 0.528526059093745 0.874674658156025 0.999999999999998 GO:0008503 benzodiazepine receptor activity 1/3206 11/18639 0.0909090909090909 0.528526059093745 0.874674658156025 0.999999999999998 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/3206 11/18639 0.0909090909090909 0.528526059093745 0.874674658156025 0.999999999999998 GO:0015205 nucleobase transmembrane transporter activity 1/3206 11/18639 0.0909090909090909 0.528526059093745 0.874674658156025 0.999999999999998 GO:0016594 glycine binding 1/3206 11/18639 0.0909090909090909 0.528526059093745 0.874674658156025 0.999999999999998 GO:0019203 carbohydrate phosphatase activity 1/3206 11/18639 0.0909090909090909 0.528526059093745 0.874674658156025 0.999999999999998 GO:0031731 CCR6 chemokine receptor binding 1/3206 11/18639 0.0909090909090909 0.528526059093745 0.874674658156025 0.999999999999998 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/3206 11/18639 0.0909090909090909 0.528526059093745 0.874674658156025 0.999999999999998 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/3206 11/18639 0.0909090909090909 0.528526059093745 0.874674658156025 0.999999999999998 GO:0070697 activin receptor binding 1/3206 11/18639 0.0909090909090909 0.528526059093745 0.874674658156025 0.999999999999998 GO:0140031 phosphorylation-dependent protein binding 1/3206 11/18639 0.0909090909090909 0.528526059093745 0.874674658156025 0.999999999999998 GO:1900750 oligopeptide binding 1/3206 11/18639 0.0909090909090909 0.528526059093745 0.874674658156025 0.999999999999998 GO:0072341 modified amino acid binding 12/3206 91/18639 0.131868131868132 0.766653184619498 0.878890661287339 0.999999999999998 GO:0141108 transporter regulator activity 24/3206 170/18639 0.141176470588235 0.820769880004404 0.881387517815909 0.999999999999998 GO:0010851 cyclase regulator activity 2/3206 20/18639 0.1 0.581378665003119 0.88189397413397 0.999999999999998 GO:0051959 dynein light intermediate chain binding 3/3206 28/18639 0.107142857142857 0.622905712503342 0.882982321144301 0.999999999999998 GO:0003995 acyl-CoA dehydrogenase activity 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0004032 aldose reductase (NADPH) activity 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0004859 phospholipase inhibitor activity 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0004875 complement receptor activity 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0005165 neurotrophin receptor binding 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0005247 voltage-gated chloride channel activity 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0005436 sodium:phosphate symporter activity 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0008504 monoamine transmembrane transporter activity 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0015132 prostaglandin transmembrane transporter activity 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0015368 calcium:monoatomic cation antiporter activity 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0042301 phosphate ion binding 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0070679 inositol 1,4,5 trisphosphate binding 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0140900 chloride:bicarbonate antiporter activity 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:1990459 transferrin receptor binding 1/3206 12/18639 0.0833333333333333 0.484482220835933 0.896243964895975 0.999999999999998 GO:0004181 metallocarboxypeptidase activity 3/3206 29/18639 0.103448275862069 0.60142620517564 0.897197210398421 0.999999999999998 GO:0004629 phospholipase C activity 3/3206 29/18639 0.103448275862069 0.60142620517564 0.897197210398421 0.999999999999998 GO:0036122 BMP binding 2/3206 21/18639 0.0952380952380952 0.553693966669637 0.898284180694784 0.999999999999998 GO:0051428 peptide hormone receptor binding 2/3206 21/18639 0.0952380952380952 0.553693966669637 0.898284180694784 0.999999999999998 GO:0140312 cargo adaptor activity 2/3206 21/18639 0.0952380952380952 0.553693966669637 0.898284180694784 0.999999999999998 GO:0099106 ion channel regulator activity 22/3206 160/18639 0.1375 0.799395664379289 0.90024777052355 0.999999999999998 GO:0008081 phosphoric diester hydrolase activity 11/3206 87/18639 0.126436781609195 0.73507647299245 0.902390342489826 0.999999999999998 GO:0004197 cysteine-type endopeptidase activity 11/3206 88/18639 0.125 0.726723331253899 0.90998707955202 0.999999999999998 GO:0005243 gap junction channel activity 2/3206 22/18639 0.0909090909090909 0.528526059093745 0.912532251170926 0.999999999999998 GO:0008970 phospholipase A1 activity 2/3206 22/18639 0.0909090909090909 0.528526059093745 0.912532251170926 0.999999999999998 GO:0016881 acid-amino acid ligase activity 2/3206 22/18639 0.0909090909090909 0.528526059093745 0.912532251170926 0.999999999999998 GO:0031683 G-protein beta/gamma-subunit complex binding 2/3206 22/18639 0.0909090909090909 0.528526059093745 0.912532251170926 0.999999999999998 GO:0033691 sialic acid binding 2/3206 22/18639 0.0909090909090909 0.528526059093745 0.912532251170926 0.999999999999998 GO:0140784 metal ion sensor activity 2/3206 22/18639 0.0909090909090909 0.528526059093745 0.912532251170926 0.999999999999998 GO:0008146 sulfotransferase activity 6/3206 53/18639 0.113207547169811 0.658164526418625 0.912688137699205 0.999999999999998 GO:0004620 phospholipase activity 14/3206 109/18639 0.128440366972477 0.746724890829694 0.913484087452142 0.999999999999998 GO:0004465 lipoprotein lipase activity 1/3206 13/18639 0.0769230769230769 0.447214357694707 0.914102012275773 0.999999999999998 GO:0005035 death receptor activity 1/3206 13/18639 0.0769230769230769 0.447214357694707 0.914102012275773 0.999999999999998 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/3206 13/18639 0.0769230769230769 0.447214357694707 0.914102012275773 0.999999999999998 GO:0017154 semaphorin receptor activity 1/3206 13/18639 0.0769230769230769 0.447214357694707 0.914102012275773 0.999999999999998 GO:0071714 icosanoid transmembrane transporter activity 1/3206 13/18639 0.0769230769230769 0.447214357694707 0.914102012275773 0.999999999999998 GO:0089720 caspase binding 1/3206 13/18639 0.0769230769230769 0.447214357694707 0.914102012275773 0.999999999999998 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/3206 13/18639 0.0769230769230769 0.447214357694707 0.914102012275773 0.999999999999998 GO:0015294 solute:monoatomic cation symporter activity 15/3206 116/18639 0.129310344827586 0.751782756469551 0.914972945799974 0.999999999999998 GO:0004180 carboxypeptidase activity 5/3206 46/18639 0.108695652173913 0.63193333152513 0.91630400776871 0.999999999999998 GO:0015026 coreceptor activity 7/3206 61/18639 0.114754098360656 0.667155845085547 0.918889995392531 0.999999999999998 GO:0005184 neuropeptide hormone activity 3/3206 31/18639 0.0967741935483871 0.562624514519148 0.921049186251558 0.999999999999998 GO:0005452 solute:inorganic anion antiporter activity 3/3206 31/18639 0.0967741935483871 0.562624514519148 0.921049186251558 0.999999999999998 GO:0005539 glycosaminoglycan binding 34/3206 242/18639 0.140495867768595 0.816813000417606 0.921133876967877 0.999999999999998 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/3206 23/18639 0.0869565217391304 0.505546665220104 0.924889930469347 0.999999999999998 GO:0004022 alcohol dehydrogenase (NAD+) activity 2/3206 23/18639 0.0869565217391304 0.505546665220104 0.924889930469347 0.999999999999998 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/3206 23/18639 0.0869565217391304 0.505546665220104 0.924889930469347 0.999999999999998 GO:0005543 phospholipid binding 74/3206 497/18639 0.148893360160966 0.865634229582109 0.927709005033281 0.999999999999998 GO:0008201 heparin binding 23/3206 172/18639 0.133720930232558 0.777424959015799 0.928602249002023 0.999999999999998 GO:0008191 metalloendopeptidase inhibitor activity 1/3206 14/18639 0.0714285714285714 0.415270475002228 0.928887202259875 0.999999999999998 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/3206 14/18639 0.0714285714285714 0.415270475002228 0.928887202259875 0.999999999999998 GO:0031404 chloride ion binding 1/3206 14/18639 0.0714285714285714 0.415270475002228 0.928887202259875 0.999999999999998 GO:0032454 histone H3K9 demethylase activity 1/3206 14/18639 0.0714285714285714 0.415270475002228 0.928887202259875 0.999999999999998 GO:0042813 Wnt receptor activity 1/3206 14/18639 0.0714285714285714 0.415270475002228 0.928887202259875 0.999999999999998 GO:0043176 amine binding 1/3206 14/18639 0.0714285714285714 0.415270475002228 0.928887202259875 0.999999999999998 GO:0160041 neuropeptide activity 3/3206 32/18639 0.09375 0.545042498440424 0.930971322946654 0.999999999999998 GO:0004806 triacylglycerol lipase activity 2/3206 24/18639 0.0833333333333333 0.484482220835933 0.935585765740539 0.999999999999998 GO:0015149 hexose transmembrane transporter activity 2/3206 24/18639 0.0833333333333333 0.484482220835933 0.935585765740539 0.999999999999998 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/3206 24/18639 0.0833333333333333 0.484482220835933 0.935585765740539 0.999999999999998 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/3206 24/18639 0.0833333333333333 0.484482220835933 0.935585765740539 0.999999999999998 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/3206 24/18639 0.0833333333333333 0.484482220835933 0.935585765740539 0.999999999999998 GO:0055056 D-glucose transmembrane transporter activity 2/3206 24/18639 0.0833333333333333 0.484482220835933 0.935585765740539 0.999999999999998 GO:0008236 serine-type peptidase activity 26/3206 194/18639 0.134020618556701 0.779167282993871 0.9376150054854 0.999999999999998 GO:0019239 deaminase activity 3/3206 33/18639 0.0909090909090909 0.528526059093745 0.939733077477817 0.999999999999998 GO:0035254 glutamate receptor binding 5/3206 49/18639 0.102040816326531 0.593243535717469 0.940405087738836 0.999999999999998 GO:0004089 carbonate dehydratase activity 1/3206 15/18639 0.0666666666666667 0.387585776668746 0.941128148813155 0.999999999999998 GO:0004953 icosanoid receptor activity 1/3206 15/18639 0.0666666666666667 0.387585776668746 0.941128148813155 0.999999999999998 GO:0015116 sulfate transmembrane transporter activity 1/3206 15/18639 0.0666666666666667 0.387585776668746 0.941128148813155 0.999999999999998 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/3206 15/18639 0.0666666666666667 0.387585776668746 0.941128148813155 0.999999999999998 GO:0017081 chloride channel regulator activity 1/3206 15/18639 0.0666666666666667 0.387585776668746 0.941128148813155 0.999999999999998 GO:0030553 cGMP binding 1/3206 15/18639 0.0666666666666667 0.387585776668746 0.941128148813155 0.999999999999998 GO:0031005 filamin binding 1/3206 15/18639 0.0666666666666667 0.387585776668746 0.941128148813155 0.999999999999998 GO:0050700 CARD domain binding 1/3206 15/18639 0.0666666666666667 0.387585776668746 0.941128148813155 0.999999999999998 GO:0001848 complement binding 2/3206 25/18639 0.08 0.465102932002495 0.944825636384233 0.999999999999998 GO:0003707 nuclear steroid receptor activity 2/3206 25/18639 0.08 0.465102932002495 0.944825636384233 0.999999999999998 GO:0048020 CCR chemokine receptor binding 5/3206 50/18639 0.1 0.581378665003119 0.946926803029443 0.999999999999998 GO:0015020 glucuronosyltransferase activity 3/3206 34/18639 0.0882352941176471 0.512981175002752 0.947454469929151 0.999999999999998 GO:0051427 hormone receptor binding 3/3206 34/18639 0.0882352941176471 0.512981175002752 0.947454469929151 0.999999999999998 GO:0061135 endopeptidase regulator activity 24/3206 184/18639 0.130434782608696 0.758319997830155 0.949323303242741 0.999999999999998 GO:0015385 sodium:proton antiporter activity 1/3206 16/18639 0.0625 0.363361665626949 0.951262553608313 0.999999999999998 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/3206 16/18639 0.0625 0.363361665626949 0.951262553608313 0.999999999999998 GO:0017171 serine hydrolase activity 26/3206 198/18639 0.131313131313131 0.763426529802076 0.951390905355619 0.999999999999998 GO:0004435 phosphatidylinositol phospholipase C activity 2/3206 26/18639 0.0769230769230769 0.447214357694707 0.952793787967008 0.999999999999998 GO:0005112 Notch binding 2/3206 26/18639 0.0769230769230769 0.447214357694707 0.952793787967008 0.999999999999998 GO:0005227 calcium-activated cation channel activity 2/3206 26/18639 0.0769230769230769 0.447214357694707 0.952793787967008 0.999999999999998 GO:0015145 monosaccharide transmembrane transporter activity 2/3206 26/18639 0.0769230769230769 0.447214357694707 0.952793787967008 0.999999999999998 GO:0015293 symporter activity 18/3206 146/18639 0.123287671232877 0.716768217127133 0.957984869936894 0.999999999999998 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/3206 17/18639 0.0588235294117647 0.341987450001835 0.959652837296856 0.999999999999998 GO:0015278 intracellularly gated calcium channel activity 1/3206 17/18639 0.0588235294117647 0.341987450001835 0.959652837296856 0.999999999999998 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/3206 17/18639 0.0588235294117647 0.341987450001835 0.959652837296856 0.999999999999998 GO:0019198 transmembrane receptor protein phosphatase activity 1/3206 17/18639 0.0588235294117647 0.341987450001835 0.959652837296856 0.999999999999998 GO:0030548 acetylcholine receptor regulator activity 1/3206 17/18639 0.0588235294117647 0.341987450001835 0.959652837296856 0.999999999999998 GO:0045236 CXCR chemokine receptor binding 1/3206 17/18639 0.0588235294117647 0.341987450001835 0.959652837296856 0.999999999999998 GO:0070403 NAD+ binding 1/3206 17/18639 0.0588235294117647 0.341987450001835 0.959652837296856 0.999999999999998 GO:0035255 ionotropic glutamate receptor binding 2/3206 27/18639 0.0740740740740741 0.430650862965273 0.959654181114193 0.999999999999998 GO:0004190 aspartic-type endopeptidase activity 3/3206 36/18639 0.0833333333333333 0.484482220835933 0.960209122011928 0.999999999999998 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 36/3206 268/18639 0.134328358208955 0.780956415675832 0.96140347559382 0.999999999999998 GO:0004252 serine-type endopeptidase activity 22/3206 176/18639 0.125 0.726723331253899 0.965194997224423 0.999999999999998 GO:0070001 aspartic-type peptidase activity 3/3206 37/18639 0.0810810810810811 0.471388106759286 0.965435851494399 0.999999999999998 GO:0051119 sugar transmembrane transporter activity 2/3206 28/18639 0.0714285714285714 0.415270475002228 0.965552016496493 0.999999999999998 GO:0051393 alpha-actinin binding 2/3206 28/18639 0.0714285714285714 0.415270475002228 0.965552016496493 0.999999999999998 GO:0008509 monoatomic anion transmembrane transporter activity 18/3206 149/18639 0.120805369127517 0.702336642285647 0.966561552281025 0.999999999999998 GO:0017075 syntaxin-1 binding 1/3206 18/18639 0.0555555555555556 0.322988147223955 0.966599083866842 0.999999999999998 GO:0032393 MHC class I receptor activity 1/3206 18/18639 0.0555555555555556 0.322988147223955 0.966599083866842 0.999999999999998 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/3206 18/18639 0.0555555555555556 0.322988147223955 0.966599083866842 0.999999999999998 GO:0001217 DNA-binding transcription repressor activity 37/3206 278/18639 0.133093525179856 0.773777359896238 0.968326740850465 0.999999999999998 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 9/3206 86/18639 0.104651162790698 0.608419533142799 0.970833527871632 0.999999999999998 GO:0016298 lipase activity 15/3206 130/18639 0.115384615384615 0.670821536542061 0.971721800125073 0.999999999999998 GO:0042577 lipid phosphatase activity 1/3206 19/18639 0.0526315789473684 0.305988771054273 0.972349759830695 0.999999999999998 GO:0042834 peptidoglycan binding 1/3206 19/18639 0.0526315789473684 0.305988771054273 0.972349759830695 0.999999999999998 GO:0042379 chemokine receptor binding 7/3206 72/18639 0.0972222222222222 0.565229257641921 0.974461597311048 0.999999999999998 GO:0022839 monoatomic ion-gated channel activity 2/3206 30/18639 0.0666666666666667 0.387585776668746 0.974956625229529 0.999999999999998 GO:0001972 retinoic acid binding 1/3206 20/18639 0.05 0.29068933250156 0.977110590656839 0.999999999999998 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/3206 20/18639 0.05 0.29068933250156 0.977110590656839 0.999999999999998 GO:0005326 neurotransmitter transmembrane transporter activity 1/3206 20/18639 0.05 0.29068933250156 0.977110590656839 0.999999999999998 GO:0001664 G protein-coupled receptor binding 39/3206 297/18639 0.131313131313131 0.763426529802076 0.977450404078991 0.999999999999998 GO:0005164 tumor necrosis factor receptor binding 2/3206 31/18639 0.0645161290322581 0.375083009679432 0.978674379641803 0.999999999999998 GO:0004175 endopeptidase activity 55/3206 405/18639 0.135802469135802 0.789526582103001 0.980623839967777 0.999999999999998 GO:0032813 tumor necrosis factor receptor superfamily binding 4/3206 50/18639 0.08 0.465102932002495 0.980993878937118 0.999999999999998 GO:0005123 death receptor binding 1/3206 21/18639 0.0476190476190476 0.276846983334819 0.981051911154941 0.999999999999998 GO:0009975 cyclase activity 1/3206 21/18639 0.0476190476190476 0.276846983334819 0.981051911154941 0.999999999999998 GO:0061891 calcium ion sensor activity 1/3206 21/18639 0.0476190476190476 0.276846983334819 0.981051911154941 0.999999999999998 GO:0001540 amyloid-beta binding 8/3206 83/18639 0.0963855421686747 0.560364978316259 0.982072080037819 0.999999999999998 GO:0001786 phosphatidylserine binding 5/3206 59/18639 0.0847457627118644 0.492693783900948 0.982259583407884 0.999999999999998 GO:0031593 polyubiquitin modification-dependent protein binding 5/3206 59/18639 0.0847457627118644 0.492693783900948 0.982259583407884 0.999999999999998 GO:0004497 monooxygenase activity 11/3206 106/18639 0.10377358490566 0.603317482550407 0.982291431329447 0.999999999999998 GO:0005544 calcium-dependent phospholipid binding 4/3206 53/18639 0.0754716981132075 0.43877635094575 0.987358453467289 0.999999999999998 GO:0004866 endopeptidase inhibitor activity 18/3206 161/18639 0.111801242236025 0.649988569568705 0.987378607088775 0.999999999999998 GO:0005179 hormone activity 14/3206 132/18639 0.106060606060606 0.616613735609369 0.987546592919499 0.999999999999998 GO:0030414 peptidase inhibitor activity 19/3206 169/18639 0.112426035502959 0.653620984323033 0.988218121459166 0.999999999999998 GO:0015370 solute:sodium symporter activity 7/3206 79/18639 0.0886075949367089 0.515145652534409 0.988523798134622 0.999999999999998 GO:0004867 serine-type endopeptidase inhibitor activity 9/3206 95/18639 0.0947368421052632 0.550779787897692 0.988643250793273 0.999999999999998 GO:0008009 chemokine activity 3/3206 45/18639 0.0666666666666667 0.387585776668746 0.989200842130347 0.999999999999998 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/3206 24/18639 0.0416666666666667 0.242241110417966 0.989251972302897 0.999999999999998 GO:0001216 DNA-binding transcription activator activity 66/3206 491/18639 0.134419551934827 0.781486596541871 0.990808320999387 0.999999999999998 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/3206 25/18639 0.04 0.232551466001248 0.991103069632841 0.999999999999998 GO:0042805 actinin binding 2/3206 37/18639 0.0540540540540541 0.314258737839524 0.991991915968462 0.999999999999998 GO:0030247 polysaccharide binding 1/3206 26/18639 0.0384615384615385 0.223607178847354 0.992635440899474 0.999999999999998 GO:0043548 phosphatidylinositol 3-kinase binding 1/3206 26/18639 0.0384615384615385 0.223607178847354 0.992635440899474 0.999999999999998 GO:0005104 fibroblast growth factor receptor binding 1/3206 27/18639 0.037037037037037 0.215325431482637 0.993903950891216 0.999999999999998 GO:0008395 steroid hydroxylase activity 1/3206 27/18639 0.037037037037037 0.215325431482637 0.993903950891216 0.999999999999998 GO:0015252 proton channel activity 1/3206 27/18639 0.037037037037037 0.215325431482637 0.993903950891216 0.999999999999998 GO:0015144 carbohydrate transmembrane transporter activity 2/3206 40/18639 0.05 0.29068933250156 0.995133302728723 0.999999999999998 GO:0071855 neuropeptide receptor binding 2/3206 40/18639 0.05 0.29068933250156 0.995133302728723 0.999999999999998 GO:0005253 monoatomic anion channel activity 9/3206 103/18639 0.087378640776699 0.508000775245444 0.995349563609451 0.999999999999998 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 63/3206 484/18639 0.130165289256198 0.756753220975135 0.995483323016848 0.999999999999998 GO:0099604 ligand-gated calcium channel activity 1/3206 29/18639 0.0344827586206897 0.200475401725213 0.995823261359349 0.999999999999998 GO:0005126 cytokine receptor binding 32/3206 275/18639 0.116363636363636 0.676513355639993 0.996050776510474 0.999999999999998 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/3206 30/18639 0.0333333333333333 0.193792888334373 0.996542800536239 0.999999999999998 GO:0008083 growth factor activity 16/3206 162/18639 0.0987654320987654 0.574201150620365 0.997029471284418 0.999999999999998 GO:0015103 inorganic anion transmembrane transporter activity 16/3206 165/18639 0.096969696969697 0.563761129699994 0.99779135918949 0.999999999999998 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/3206 46/18639 0.0434782608695652 0.252773332610052 0.998226216697621 0.999999999999998 GO:0015108 chloride transmembrane transporter activity 10/3206 121/18639 0.0826446280991736 0.480478235539768 0.998507262271044 0.999999999999998 GO:0004896 cytokine receptor activity 7/3206 96/18639 0.0729166666666667 0.423921943231441 0.998600273709791 0.999999999999998 GO:0008188 neuropeptide receptor activity 2/3206 48/18639 0.0416666666666667 0.242241110417966 0.998737224132717 0.999999999999998 GO:0038187 pattern recognition receptor activity 2/3206 48/18639 0.0416666666666667 0.242241110417966 0.998737224132717 0.999999999999998 GO:0015085 calcium ion transmembrane transporter activity 13/3206 147/18639 0.0884353741496599 0.514144397621806 0.998754811017796 0.999999999999998 GO:0030280 structural constituent of skin epidermis 1/3206 37/18639 0.027027027027027 0.157129368919762 0.999079977690972 0.999999999999998 GO:0005245 voltage-gated calcium channel activity 1/3206 43/18639 0.0232558139534884 0.1352043406984 0.999704324736411 0.999999999999998 GO:0005254 chloride channel activity 4/3206 83/18639 0.0481927710843374 0.28018248915813 0.99984830946971 0.999999999999998 GO:0005272 sodium channel activity 1/3206 51/18639 0.0196078431372549 0.113995816667278 0.999934952383348 0.999999999999998 GO:0008528 G protein-coupled peptide receptor activity 7/3206 122/18639 0.0573770491803279 0.333577922542773 0.999959397382277 0.999999999999998 GO:0015081 sodium ion transmembrane transporter activity 11/3206 164/18639 0.0670731707317073 0.389949104575263 0.99997888905539 0.999999999999998 GO:0001653 peptide receptor activity 7/3206 128/18639 0.0546875 0.317941457423581 0.999982793046388 0.999999999999998 GO:0005262 calcium channel activity 7/3206 131/18639 0.0534351145038168 0.310660355345178 0.999988852656657 0.999999999999998 GO:0046873 metal ion transmembrane transporter activity 46/3206 450/18639 0.102222222222222 0.594298190892077 0.999990932290024 0.999999999999998 GO:0003823 antigen binding 11/3206 174/18639 0.0632183908045977 0.367538236496225 0.999994335995951 0.999999999999998 GO:0140375 immune receptor activity 9/3206 156/18639 0.0576923076923077 0.33541076827103 0.999994906849461 0.999999999999998 GO:0005125 cytokine activity 16/3206 234/18639 0.0683760683760684 0.397523873506406 0.999999174392134 0.999999999999998 GO:0030527 structural constituent of chromatin 2/3206 98/18639 0.0204081632653061 0.118648707143494 0.999999811288134 0.999999999999998 GO:0099094 ligand-gated monoatomic cation channel activity 4/3206 136/18639 0.0294117647058824 0.170993725000917 0.999999973047869 0.999999999999998 GO:0030594 neurotransmitter receptor activity 1/3206 97/18639 0.0103092783505155 0.0599359448456824 0.999999989381364 0.999999999999998 GO:0005244 voltage-gated monoatomic ion channel activity 6/3206 173/18639 0.0346820809248555 0.201634219076226 0.999999996793105 0.999999999999998 GO:0022832 voltage-gated channel activity 6/3206 175/18639 0.0342857142857143 0.199329828001069 0.999999997681561 0.999999999999998 GO:0005267 potassium channel activity 2/3206 124/18639 0.0161290322580645 0.0937707524198579 0.999999998305004 0.999999999999998 GO:0015079 potassium ion transmembrane transporter activity 4/3206 160/18639 0.025 0.14534466625078 0.999999999549287 0.999999999999998 GO:0022834 ligand-gated channel activity 5/3206 188/18639 0.0265957446808511 0.15462198537317 0.999999999965164 0.999999999999998 GO:0015276 ligand-gated monoatomic ion channel activity 4/3206 186/18639 0.021505376344086 0.125027669893144 0.999999999995051 0.999999999999998 GO:0045182 translation regulator activity 19/3206 356/18639 0.0533707865168539 0.31028636615335 0.999999999997292 0.999999999999998 GO:0022843 voltage-gated monoatomic cation channel activity 1/3206 143/18639 0.00699300699300699 0.0406558506995188 0.999999999998307 0.999999999999998 GO:0022836 gated channel activity 13/3206 318/18639 0.0408805031446541 0.237670523428948 0.999999999999913 0.999999999999998 GO:0030371 translation repressor activity 12/3206 329/18639 0.0364741641337386 0.212053008511776 0.999999999999997 0.999999999999998 GO:0005261 monoatomic cation channel activity 13/3206 341/18639 0.0381231671554252 0.221639960265119 0.999999999999998 0.999999999999998 GO:0005216 monoatomic ion channel activity 23/3206 448/18639 0.0513392857142857 0.298475653907851 0.999999999999998 0.999999999999998