ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	105/3091	175/18639	0.6	3.61805241022323	1.15752226489606e-38	1.50477894436488e-35
GO:0045296	cadherin binding	115/3091	334/18639	0.344311377245509	2.07622768051732	9.33285144193012e-16	6.06635343725458e-13
GO:0003697	single-stranded DNA binding	53/3091	121/18639	0.43801652892562	2.64127793032825	1.5982731715091e-12	6.92585040987279e-10
GO:0140097	catalytic activity, acting on DNA	106/3091	336/18639	0.31547619047619	1.90234898553404	6.85139120241818e-12	2.22670214078591e-09
GO:0016853	isomerase activity	67/3091	180/18639	0.372222222222222	2.2445325137496	1.85153982038457e-11	4.81400353299989e-09
GO:0008094	ATP-dependent activity, acting on DNA	70/3091	210/18639	0.333333333333333	2.01002911679068	1.89336251339148e-09	4.10228544568154e-07
GO:0140104	molecular carrier activity	78/3091	249/18639	0.313253012048193	1.88894302541775	5.72632544233394e-09	1.06346043929059e-06
GO:0003678	DNA helicase activity	33/3091	74/18639	0.445945945945946	2.68909300759835	1.44063724051675e-08	2.0809204585242e-06
GO:0003684	damaged DNA binding	33/3091	74/18639	0.445945945945946	2.68909300759835	1.44063724051675e-08	2.0809204585242e-06
GO:0000217	DNA secondary structure binding	22/3091	39/18639	0.564102564102564	3.40158773610731	1.77924532030851e-08	2.31301891640106e-06
GO:0004386	helicase activity	53/3091	155/18639	0.341935483870968	2.06190083593367	6.5254352453017e-08	7.71187801717473e-06
GO:0003712	transcription coregulator activity	128/3091	495/18639	0.258585858585859	1.55929531484368	7.49529724031793e-08	8.11990534367776e-06
GO:0017116	single-stranded DNA helicase activity	27/3091	58/18639	0.46551724137931	2.80710962862147	9.78047500205838e-08	9.78047500205838e-06
GO:0019843	rRNA binding	29/3091	65/18639	0.446153846153846	2.69034666401214	1.056066079452e-07	9.80632788062571e-06
GO:0016887	ATP hydrolysis activity	110/3091	417/18639	0.26378896882494	1.59067052407896	2.09577791212462e-07	1.81634085717467e-05
GO:0003714	transcription corepressor activity	63/3091	204/18639	0.308823529411765	1.86223285820313	2.85516402893526e-07	2.3198207735099e-05
GO:0042393	histone binding	72/3091	247/18639	0.291497975708502	1.7577582559789	5.14350388499321e-07	3.93326767675951e-05
GO:0048027	mRNA 5'-UTR binding	15/3091	24/18639	0.625	3.76880459398253	5.54264772344968e-07	4.00302335582477e-05
GO:0031720	haptoglobin binding	9/3091	10/18639	0.9	5.42707861533484	7.99558090321298e-07	5.47066061798783e-05
GO:0019838	growth factor binding	45/3091	136/18639	0.330882352941176	1.99524949093193	1.75092879900637e-06	0.000112690294817275
GO:0055105	ubiquitin-protein transferase inhibitor activity	11/3091	15/18639	0.733333333333333	4.4220640569395	1.82038168550982e-06	0.000112690294817275
GO:0000400	four-way junction DNA binding	12/3091	18/18639	0.666666666666667	4.02005823358137	2.92996857279259e-06	0.000173134506574108
GO:0055106	ubiquitin-protein transferase regulator activity	18/3091	36/18639	0.5	3.01504367518602	3.727125963653e-06	0.000202016076736831
GO:1990948	ubiquitin ligase inhibitor activity	9/3091	11/18639	0.818181818181818	4.93370783212259	3.74394588333396e-06	0.000202016076736831
GO:0016860	intramolecular oxidoreductase activity	23/3091	53/18639	0.433962264150943	2.61683035959542	3.88492455263137e-06	0.000202016076736831
GO:0008135	translation factor activity, RNA binding	31/3091	83/18639	0.373493975903614	2.25220129953655	4.26537409773023e-06	0.000213268704886512
GO:0003688	DNA replication origin binding	11/3091	16/18639	0.6875	4.14568505338078	4.94672271443937e-06	0.000238175538102636
GO:0180051	translation factor activity	31/3091	84/18639	0.369047619047619	2.22538937930397	5.69460651609511e-06	0.00026439244539013
GO:0051082	unfolded protein binding	40/3091	121/18639	0.330578512396694	1.99341730590811	6.59506891939288e-06	0.000295641020524508
GO:0003743	translation initiation factor activity	22/3091	51/18639	0.431372549019608	2.60121415114088	7.07344560647466e-06	0.000306515976280569
GO:0003689	DNA clamp loader activity	49/3091	160/18639	0.30625	1.84671425105144	7.40315323077379e-06	0.000310454812903417
GO:0005344	oxygen carrier activity	10/3091	14/18639	0.714285714285714	4.30720525026575	8.11974069479079e-06	0.000329864465725876
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	24/3091	59/18639	0.406779661016949	2.45291688828693	9.38441239762573e-06	0.000369688973239801
GO:0031625	ubiquitin protein ligase binding	79/3091	302/18639	0.26158940397351	1.57740695589203	1.43555202315897e-05	0.000548887538266666
GO:0004601	peroxidase activity	23/3091	57/18639	0.403508771929825	2.43319314137819	1.67789774687137e-05	0.000623219163123651
GO:0140597	protein carrier chaperone	54/3091	188/18639	0.287234042553192	1.73204636659623	2.05499859543593e-05	0.00074208282612964
GO:0070182	DNA polymerase binding	12/3091	21/18639	0.571428571428571	3.4457642002126	2.83484213384795e-05	0.000978768270750755
GO:0044389	ubiquitin-like protein ligase binding	82/3091	322/18639	0.254658385093168	1.53561230661648	2.86101494527144e-05	0.000978768270750755
GO:0140713	histone chaperone activity	48/3091	164/18639	0.292682926829268	1.76490361474304	3.41083978566521e-05	0.00113694659522174
GO:0017070	U6 snRNA binding	10/3091	16/18639	0.625	3.76880459398253	4.70046853782083e-05	0.00152765227479177
GO:0140658	ATP-dependent chromatin remodeler activity	46/3091	158/18639	0.291139240506329	1.75559505137414	5.67029482663574e-05	0.00179789835966499
GO:0015631	tubulin binding	93/3091	385/18639	0.241558441558442	1.45661850281714	7.62904575667353e-05	0.00236137130563704
GO:0016209	antioxidant activity	29/3091	86/18639	0.337209302325581	2.03340154838127	7.81661468130167e-05	0.00236316257806795
GO:0061749	forked DNA-dependent helicase activity	19/3091	47/18639	0.404255319148936	2.43769488632061	8.69232350344187e-05	0.00256818648965328
GO:0015616	DNA translocase activity	44/3091	152/18639	0.289473684210526	1.74555160142349	9.41619205646359e-05	0.00272023326075615
GO:0008017	microtubule binding	70/3091	276/18639	0.253623188405797	1.52936998016682	0.000121166319055846	0.00329504317729069
GO:0009378	four-way junction helicase activity	19/3091	48/18639	0.395833333333333	2.38690957618894	0.000121663132699964	0.00329504317729069
GO:0036121	double-stranded DNA helicase activity	19/3091	48/18639	0.395833333333333	2.38690957618894	0.000121663132699964	0.00329504317729069
GO:0016829	lyase activity	54/3091	200/18639	0.27	1.62812358460045	0.000127595356016065	0.00338518291471192
GO:0000510	H3-H4 histone complex chaperone activity	43/3091	151/18639	0.28476821192053	1.71717719249005	0.000168470274559684	0.00413228975335075
GO:0140584	chromatin extrusion motor activity	43/3091	151/18639	0.28476821192053	1.71717719249005	0.000168470274559684	0.00413228975335075
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	43/3091	151/18639	0.28476821192053	1.71717719249005	0.000168470274559684	0.00413228975335075
GO:0140849	ATP-dependent H2AZ histone chaperone activity	43/3091	151/18639	0.28476821192053	1.71717719249005	0.000168470274559684	0.00413228975335075
GO:0031386	protein tag activity	9/3091	15/18639	0.6	3.61805241022323	0.000179561640220903	0.00424418422340317
GO:0141047	molecular tag activity	9/3091	15/18639	0.6	3.61805241022323	0.000179561640220903	0.00424418422340317
GO:0098641	cadherin binding involved in cell-cell adhesion	10/3091	18/18639	0.555555555555556	3.35004852798447	0.000186071362185218	0.00431951376501398
GO:0140674	ATP-dependent histone chaperone activity	43/3091	152/18639	0.282894736842105	1.70587997411841	0.000197784579346719	0.00451087637106552
GO:0035064	methylated histone binding	25/3091	74/18639	0.337837837837838	2.03719167242299	0.000229538533539414	0.00510333987183012
GO:0061775	cohesin loader activity	43/3091	153/18639	0.281045751633987	1.69473043180391	0.000231613117259982	0.00510333987183012
GO:0043021	ribonucleoprotein complex binding	48/3091	177/18639	0.271186440677966	1.63527792552462	0.000262651934471152	0.00569079191354163
GO:1990518	single-stranded 3'-5' DNA helicase activity	18/3091	47/18639	0.382978723404255	2.30939515546164	0.000297103572619127	0.00633171548204698
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	15/3091	36/18639	0.416666666666667	2.51253639598835	0.000321365335033043	0.00652773336785869
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	15/3091	36/18639	0.416666666666667	2.51253639598835	0.000321365335033043	0.00652773336785869
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	15/3091	36/18639	0.416666666666667	2.51253639598835	0.000321365335033043	0.00652773336785869
GO:0140666	annealing activity	8/3091	13/18639	0.615384615384615	3.71082298484434	0.000331010638875829	0.00662021277751658
GO:0140662	ATP-dependent protein folding chaperone	16/3091	40/18639	0.4	2.41203494014882	0.000357864262459736	0.00704884153329783
GO:0140034	methylation-dependent protein binding	25/3091	76/18639	0.328947368421053	1.98358136525396	0.00036579673571769	0.00709754860347756
GO:0043138	3'-5' DNA helicase activity	18/3091	48/18639	0.375	2.26128275638952	0.000402367836570624	0.00769232628737958
GO:0009055	electron transfer activity	34/3091	116/18639	0.293103448275862	1.7674393957987	0.000434276971232914	0.00818202989279404
GO:0140297	DNA-binding transcription factor binding	109/3091	488/18639	0.223360655737705	1.34688426473474	0.000515253818644154	0.00956899948910572
GO:0003779	actin binding	100/3091	443/18639	0.225733634311512	1.36119353281536	0.000588274385098826	0.0107712211356123
GO:0030276	clathrin binding	17/3091	46/18639	0.369565217391304	2.2285105425288	0.000703478216935822	0.0127016900280079
GO:0044183	protein folding chaperone	24/3091	75/18639	0.32	1.92962795211906	0.000745228230709001	0.0132711876701603
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	15/3091	39/18639	0.384615384615385	2.31926436552771	0.000884913086541138	0.0155457704392362
GO:0097718	disordered domain specific binding	12/3091	28/18639	0.428571428571429	2.58432315015945	0.000937176688097558	0.0162443959270243
GO:0003713	transcription coactivator activity	62/3091	256/18639	0.2421875	1.46041178016823	0.00103300125941332	0.0174444433789485
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	22/3091	68/18639	0.323529411764706	1.95091061335566	0.00103324780013772	0.0174444433789485
GO:0140030	modification-dependent protein binding	45/3091	173/18639	0.260115606936416	1.56851983102163	0.00104716469338844	0.0174527448898073
GO:0051540	metal cluster binding	24/3091	77/18639	0.311688311688312	1.87950774557051	0.00112997901421011	0.0185945913730777
GO:0140517	protein-RNA adaptor activity	10/3091	22/18639	0.454545454545455	2.74094879562366	0.00144840132874677	0.023536521592135
GO:0031491	nucleosome binding	23/3091	74/18639	0.310810810810811	1.87421633862915	0.00147991050168878	0.0237516500271039
GO:0016859	cis-trans isomerase activity	15/3091	42/18639	0.357142857142857	2.15360262513287	0.00212179574144492	0.0336382251692487
GO:0051536	iron-sulfur cluster binding	23/3091	76/18639	0.302631578947368	1.82489485603365	0.00218871254106807	0.0338729321831963
GO:0098631	cell adhesion mediator activity	23/3091	76/18639	0.302631578947368	1.82489485603365	0.00218871254106807	0.0338729321831963
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	7/3091	13/18639	0.538461538461538	3.24697011173879	0.00231806507389633	0.0345691419875905
GO:0031994	insulin-like growth factor I binding	7/3091	13/18639	0.538461538461538	3.24697011173879	0.00231806507389633	0.0345691419875905
GO:0070063	RNA polymerase binding	19/3091	59/18639	0.322033898305085	1.94189253656049	0.00235030847330242	0.0345691419875905
GO:0001094	TFIID-class transcription factor complex binding	6/3091	10/18639	0.6	3.61805241022323	0.00236665664376581	0.0345691419875905
GO:0032356	oxidized DNA binding	6/3091	10/18639	0.6	3.61805241022323	0.00236665664376581	0.0345691419875905
GO:1990841	promoter-specific chromatin binding	21/3091	68/18639	0.308823529411765	1.86223285820313	0.00254276215377893	0.0367287866656957
GO:0140664	ATP-dependent DNA damage sensor activity	9/3091	20/18639	0.45	2.71353930766742	0.00272704892940885	0.0389578418486979
GO:0001098	basal transcription machinery binding	19/3091	60/18639	0.316666666666667	1.90952766095115	0.00291358405951239	0.0402942476315543
GO:0001099	basal RNA polymerase II transcription machinery binding	19/3091	60/18639	0.316666666666667	1.90952766095115	0.00291358405951239	0.0402942476315543
GO:0004714	transmembrane receptor protein tyrosine kinase activity	19/3091	60/18639	0.316666666666667	1.90952766095115	0.00291358405951239	0.0402942476315543
GO:0140612	DNA damage sensor activity	10/3091	24/18639	0.416666666666667	2.51253639598835	0.00319452622307519	0.0437145693683973
GO:0038024	cargo receptor activity	20/3091	65/18639	0.307692307692308	1.85541149242217	0.00333623003267638	0.0451781150258259
GO:0030515	snoRNA binding	12/3091	32/18639	0.375	2.26128275638952	0.00364375756176988	0.0488338642299057
GO:0051015	actin filament binding	50/3091	209/18639	0.239234449760766	1.44260462927561	0.00388063640859318	0.0514778299099095
GO:0019842	vitamin binding	38/3091	150/18639	0.253333333333333	1.52762212876092	0.0040064109172247	0.0525883078132276
GO:0140312	cargo adaptor activity	9/3091	21/18639	0.428571428571429	2.58432315015945	0.00407714880251143	0.0525883078132276
GO:0140296	general transcription initiation factor binding	17/3091	53/18639	0.320754716981132	1.93417896144009	0.00408570699164307	0.0525883078132276
GO:0019208	phosphatase regulator activity	31/3091	117/18639	0.264957264957265	1.59771545180798	0.00435017009125679	0.055351240654005
GO:0003727	single-stranded RNA binding	25/3091	89/18639	0.280898876404494	1.69384476134046	0.00438552137489424	0.055351240654005
GO:0048407	platelet-derived growth factor binding	6/3091	11/18639	0.545454545454545	3.28913855474839	0.00447825906067296	0.0555666635741837
GO:0000049	tRNA binding	23/3091	80/18639	0.2875	1.73365011323196	0.00448807667329945	0.0555666635741837
GO:0008137	NADH dehydrogenase (ubiquinone) activity	14/3091	41/18639	0.341463414634146	2.05905421720021	0.0047175796533883	0.0578571089566489
GO:0003746	translation elongation factor activity	8/3091	18/18639	0.444444444444444	2.68003882238758	0.00515061182483121	0.0619981052988942
GO:0035615	clathrin adaptor activity	8/3091	18/18639	0.444444444444444	2.68003882238758	0.00515061182483121	0.0619981052988942
GO:0005201	extracellular matrix structural constituent	41/3091	168/18639	0.244047619047619	1.47162846050746	0.00582160498373533	0.0694319860445499
GO:0072341	modified amino acid binding	25/3091	91/18639	0.274725274725275	1.65661740394836	0.00598885200774816	0.0707773419097509
GO:0098632	cell-cell adhesion mediator activity	17/3091	55/18639	0.309090909090909	1.86384518102409	0.00621215087251628	0.072754920128569
GO:0001221	transcription coregulator binding	30/3091	115/18639	0.260869565217391	1.57306626531445	0.00631466379585604	0.073295204773329
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	7/3091	15/18639	0.466666666666667	2.81404076350696	0.00639724123375051	0.0735965805652713
GO:0016830	carbon-carbon lyase activity	16/3091	51/18639	0.313725490196078	1.89179210992064	0.00667698204417813	0.0761410233108032
GO:0019199	transmembrane receptor protein kinase activity	22/3091	78/18639	0.282051282051282	1.70079386805365	0.00687200676366377	0.0776835547196774
GO:0048029	monosaccharide binding	21/3091	74/18639	0.283783783783784	1.71124100483531	0.00756423776190945	0.0846577920919221
GO:0008301	DNA binding, bending	8/3091	19/18639	0.421052631578947	2.53898414752507	0.00761920128827299	0.0846577920919221
GO:0005525	GTP binding	81/3091	378/18639	0.214285714285714	1.29216157507972	0.00774233661957609	0.0852969288597366
GO:0017134	fibroblast growth factor binding	9/3091	23/18639	0.391304347826087	2.35959939797167	0.00828345633473283	0.090491539791199
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	18/3091	61/18639	0.295081967213115	1.7793700378147	0.00839279600120234	0.090921956679692
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	15/3091	48/18639	0.3125	1.88440229699127	0.00882543046517217	0.0948186744192051
GO:0003954	NADH dehydrogenase activity	14/3091	44/18639	0.318181818181818	1.91866415693656	0.00946058714988084	0.0999899454865455
GO:0030020	extracellular matrix structural constituent conferring tensile strength	14/3091	44/18639	0.318181818181818	1.91866415693656	0.00946058714988084	0.0999899454865455
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	32/3091	128/18639	0.25	1.50752183759301	0.00954309943760264	0.100048623136157
GO:0005159	insulin-like growth factor receptor binding	7/3091	16/18639	0.4375	2.63816321578777	0.00976425273222445	0.101548228415134
GO:0015036	disulfide oxidoreductase activity	13/3091	40/18639	0.325	1.95977838887092	0.0100732069115106	0.103929912579078
GO:0016741	transferase activity, transferring one-carbon groups	49/3091	215/18639	0.227906976744186	1.37429897752665	0.0109949236318176	0.112546462372936
GO:0050660	flavin adenine dinucleotide binding	23/3091	86/18639	0.267441860465116	1.61269777975066	0.011429744780776	0.116083345429756
GO:0051539	4 iron, 4 sulfur cluster binding	14/3091	45/18639	0.311111111111111	1.8760271756713	0.0116831835321169	0.117737508463194
GO:0005507	copper ion binding	18/3091	63/18639	0.285714285714286	1.7228821001063	0.0119216284340997	0.118489664827665
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	16/3091	54/18639	0.296296296296296	1.78669254825838	0.012031258274809	0.118489664827665
GO:0017069	snRNA binding	16/3091	54/18639	0.296296296296296	1.78669254825838	0.012031258274809	0.118489664827665
GO:0004713	protein tyrosine kinase activity	34/3091	140/18639	0.242857142857143	1.46444978509035	0.0121266621874602	0.118531284539084
GO:0005542	folic acid binding	6/3091	13/18639	0.461538461538462	2.78311723863325	0.0123286971740871	0.118720787602321
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	6/3091	13/18639	0.461538461538462	2.78311723863325	0.0123286971740871	0.118720787602321
GO:0004536	DNA nuclease activity	18/3091	64/18639	0.28125	1.69596206729214	0.0140789416130132	0.134578118359685
GO:0019887	protein kinase regulator activity	56/3091	255/18639	0.219607843137255	1.32425447694445	0.0147728144348399	0.137396287713499
GO:0002039	p53 binding	19/3091	69/18639	0.27536231884058	1.66045883560969	0.0149183732778376	0.137396287713499
GO:0003680	minor groove of adenine-thymine-rich DNA binding	5/3091	10/18639	0.5	3.01504367518602	0.0151135916484849	0.137396287713499
GO:0016783	sulfurtransferase activity	5/3091	10/18639	0.5	3.01504367518602	0.0151135916484849	0.137396287713499
GO:0047429	nucleoside triphosphate diphosphatase activity	5/3091	10/18639	0.5	3.01504367518602	0.0151135916484849	0.137396287713499
GO:0050815	phosphoserine residue binding	5/3091	10/18639	0.5	3.01504367518602	0.0151135916484849	0.137396287713499
GO:1990757	ubiquitin ligase activator activity	5/3091	10/18639	0.5	3.01504367518602	0.0151135916484849	0.137396287713499
GO:0043175	RNA polymerase core enzyme binding	13/3091	42/18639	0.30952380952381	1.86645560844849	0.015493389341212	0.139870875997053
GO:0008168	methyltransferase activity	46/3091	204/18639	0.225490196078431	1.35972557900546	0.0161482153326841	0.143881760911356
GO:0000287	magnesium ion binding	51/3091	230/18639	0.221739130434783	1.33710632551728	0.0161679213092215	0.143881760911356
GO:0016835	carbon-oxygen lyase activity	21/3091	79/18639	0.265822784810127	1.60293461212422	0.0162697068107456	0.143881760911356
GO:0022853	active monoatomic ion transmembrane transporter activity	29/3091	118/18639	0.245762711864407	1.48197062000669	0.016559181522667	0.145452270131534
GO:0042162	telomeric DNA binding	12/3091	38/18639	0.315789473684211	1.9042381106438	0.0167104532468234	0.145795900811211
GO:0140938	histone H3 methyltransferase activity	14/3091	47/18639	0.297872340425532	1.79619623202572	0.0173256033120588	0.149600468097694
GO:0097110	scaffold protein binding	19/3091	70/18639	0.271428571428571	1.63673799510098	0.0173766697559629	0.149600468097694
GO:0015035	protein-disulfide reductase activity	11/3091	34/18639	0.323529411764706	1.95091061335566	0.0178976571258094	0.152071596493806
GO:0016831	carboxy-lyase activity	11/3091	34/18639	0.323529411764706	1.95091061335566	0.0178976571258094	0.152071596493806
GO:0008174	mRNA methyltransferase activity	6/3091	14/18639	0.428571428571429	2.58432315015945	0.0185931353305243	0.154942794421036
GO:0061665	SUMO ligase activity	6/3091	14/18639	0.428571428571429	2.58432315015945	0.0185931353305243	0.154942794421036
GO:0070742	C2H2 zinc finger domain binding	6/3091	14/18639	0.428571428571429	2.58432315015945	0.0185931353305243	0.154942794421036
GO:0050750	low-density lipoprotein particle receptor binding	9/3091	26/18639	0.346153846153846	2.08733792897494	0.0198482017677575	0.16260854875024
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	7/3091	18/18639	0.388888888888889	2.34503396958913	0.0200558013185891	0.16260854875024
GO:0031690	adrenergic receptor binding	7/3091	18/18639	0.388888888888889	2.34503396958913	0.0200558013185891	0.16260854875024
GO:0070064	proline-rich region binding	7/3091	18/18639	0.388888888888889	2.34503396958913	0.0200558013185891	0.16260854875024
GO:0140299	molecular sensor activity	19/3091	71/18639	0.267605633802817	1.61368534728266	0.020138443345222	0.16260854875024
GO:0019001	guanyl nucleotide binding	82/3091	400/18639	0.205	1.23616790682627	0.0217454762176362	0.173430178422866
GO:0032561	guanyl ribonucleotide binding	82/3091	400/18639	0.205	1.23616790682627	0.0217454762176362	0.173430178422866
GO:0019205	nucleobase-containing compound kinase activity	13/3091	44/18639	0.295454545454545	1.78161671715538	0.0228878710120252	0.180169245355453
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	38/3091	167/18639	0.227544910179641	1.3721156845158	0.023435380772708	0.180169245355453
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	16/3091	58/18639	0.275862068965517	1.66347237251643	0.023816934298551	0.180169245355453
GO:0017147	Wnt-protein binding	10/3091	31/18639	0.32258064516129	1.94518946786195	0.0239626344862423	0.180169245355453
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	5/3091	11/18639	0.454545454545455	2.74094879562366	0.0239763688049949	0.180169245355453
GO:0019206	nucleoside kinase activity	5/3091	11/18639	0.454545454545455	2.74094879562366	0.0239763688049949	0.180169245355453
GO:0032794	GTPase activating protein binding	5/3091	11/18639	0.454545454545455	2.74094879562366	0.0239763688049949	0.180169245355453
GO:0034511	U3 snoRNA binding	5/3091	11/18639	0.454545454545455	2.74094879562366	0.0239763688049949	0.180169245355453
GO:0050786	RAGE receptor binding	5/3091	11/18639	0.454545454545455	2.74094879562366	0.0239763688049949	0.180169245355453
GO:0070990	snRNP binding	5/3091	11/18639	0.454545454545455	2.74094879562366	0.0239763688049949	0.180169245355453
GO:0043022	ribosome binding	27/3091	112/18639	0.241071428571429	1.45368177196469	0.0256384159647888	0.191551383644974
GO:0051287	NAD binding	15/3091	54/18639	0.277777777777778	1.67502426399224	0.0264553336403002	0.196525335613659
GO:0004602	glutathione peroxidase activity	8/3091	23/18639	0.347826086956522	2.09742168708593	0.0267204702092612	0.197367109500225
GO:0005520	insulin-like growth factor binding	7/3091	19/18639	0.368421052631579	2.22161112908444	0.0273104846696068	0.198027776240036
GO:0008574	plus-end-directed microtubule motor activity	7/3091	19/18639	0.368421052631579	2.22161112908444	0.0273104846696068	0.198027776240036
GO:0042800	histone H3K4 methyltransferase activity	7/3091	19/18639	0.368421052631579	2.22161112908444	0.0273104846696068	0.198027776240036
GO:0000993	RNA polymerase II complex binding	11/3091	36/18639	0.305555555555556	1.84252669039146	0.0274192305563126	0.198027776240036
GO:0019902	phosphatase binding	42/3091	190/18639	0.221052631578947	1.33296667745066	0.0282685439078888	0.203033740774892
GO:0005006	epidermal growth factor receptor activity	14/3091	50/18639	0.28	1.68842445810417	0.029380989472466	0.206461007103815
GO:0005007	fibroblast growth factor receptor activity	14/3091	50/18639	0.28	1.68842445810417	0.029380989472466	0.206461007103815
GO:0005017	platelet-derived growth factor receptor activity	14/3091	50/18639	0.28	1.68842445810417	0.029380989472466	0.206461007103815
GO:0005019	platelet-derived growth factor beta-receptor activity	14/3091	50/18639	0.28	1.68842445810417	0.029380989472466	0.206461007103815
GO:0019207	kinase regulator activity	60/3091	287/18639	0.209059233449477	1.26064543910217	0.0311488730347803	0.217707177124809
GO:0016866	intramolecular transferase activity	9/3091	28/18639	0.321428571428571	1.93824236261959	0.0322026102545258	0.221838394962953
GO:0019789	SUMO transferase activity	9/3091	28/18639	0.321428571428571	1.93824236261959	0.0322026102545258	0.221838394962953
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	16/3091	60/18639	0.266666666666667	1.60802329343255	0.0322518897292293	0.221838394962953
GO:0005178	integrin binding	36/3091	161/18639	0.22360248447205	1.34834251312667	0.0341296967266413	0.22795687405132
GO:0001091	RNA polymerase II general transcription initiation factor binding	8/3091	24/18639	0.333333333333333	2.01002911679068	0.0344122981130282	0.22795687405132
GO:0050699	WW domain binding	8/3091	24/18639	0.333333333333333	2.01002911679068	0.0344122981130282	0.22795687405132
GO:0005010	insulin-like growth factor receptor activity	14/3091	51/18639	0.274509803921569	1.65531809618056	0.0345115065290367	0.22795687405132
GO:0005021	vascular endothelial growth factor receptor activity	14/3091	51/18639	0.274509803921569	1.65531809618056	0.0345115065290367	0.22795687405132
GO:0017124	SH3 domain binding	27/3091	115/18639	0.234782608695652	1.415759638783	0.0350392095578519	0.22795687405132
GO:0035401	histone H3Y41 kinase activity	27/3091	115/18639	0.234782608695652	1.415759638783	0.0350392095578519	0.22795687405132
GO:0140801	histone H2AXY142 kinase activity	27/3091	115/18639	0.234782608695652	1.415759638783	0.0350392095578519	0.22795687405132
GO:0003995	acyl-CoA dehydrogenase activity	5/3091	12/18639	0.416666666666667	2.51253639598835	0.0355963426403216	0.22795687405132
GO:0005049	nuclear export signal receptor activity	5/3091	12/18639	0.416666666666667	2.51253639598835	0.0355963426403216	0.22795687405132
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	5/3091	12/18639	0.416666666666667	2.51253639598835	0.0355963426403216	0.22795687405132
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	5/3091	12/18639	0.416666666666667	2.51253639598835	0.0355963426403216	0.22795687405132
GO:0097371	MDM2/MDM4 family protein binding	5/3091	12/18639	0.416666666666667	2.51253639598835	0.0355963426403216	0.22795687405132
GO:1990247	N6-methyladenosine-containing RNA reader activity	5/3091	12/18639	0.416666666666667	2.51253639598835	0.0355963426403216	0.22795687405132
GO:0030170	pyridoxal phosphate binding	15/3091	56/18639	0.267857142857143	1.61520196884966	0.0360219588345225	0.229290360991638
GO:0043024	ribosomal small subunit binding	7/3091	20/18639	0.35	2.11053057263022	0.0361573261563737	0.229290360991638
GO:0034450	ubiquitin-ubiquitin ligase activity	6/3091	16/18639	0.375	2.26128275638952	0.0368994185927297	0.231735479084776
GO:0097027	ubiquitin-protein transferase activator activity	6/3091	16/18639	0.375	2.26128275638952	0.0368994185927297	0.231735479084776
GO:0031072	heat shock protein binding	30/3091	131/18639	0.229007633587786	1.38093603443635	0.0373841280625219	0.233650800390762
GO:0043531	ADP binding	11/3091	38/18639	0.289473684210526	1.74555160142349	0.0401241004636094	0.249575744510489
GO:0070279	vitamin B6 binding	15/3091	57/18639	0.263157894736842	1.58686509220317	0.0416439040098145	0.257795596251233
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	8/3091	25/18639	0.32	1.92962795211906	0.0434728827270535	0.266842712655602
GO:0019888	protein phosphatase regulator activity	25/3091	107/18639	0.233644859813084	1.40889891363833	0.0435158885253751	0.266842712655602
GO:0019825	oxygen binding	10/3091	34/18639	0.294117647058824	1.7735551030506	0.0444157918602816	0.271082297738808
GO:0005003	ephrin receptor activity	14/3091	53/18639	0.264150943396226	1.59285326236243	0.0466502371216314	0.280765316009818
GO:0005005	transmembrane-ephrin receptor activity	14/3091	53/18639	0.264150943396226	1.59285326236243	0.0466502371216314	0.280765316009818
GO:0016251	RNA polymerase II general transcription initiation factor activity	14/3091	53/18639	0.264150943396226	1.59285326236243	0.0466502371216314	0.280765316009818
GO:0019903	protein phosphatase binding	32/3091	144/18639	0.222222222222222	1.34001941119379	0.0471234006230494	0.282306086681863
GO:0051087	protein-folding chaperone binding	30/3091	134/18639	0.223880597014925	1.35001955605344	0.0488544190097654	0.2869310280667
GO:0035925	mRNA 3'-UTR AU-rich region binding	9/3091	30/18639	0.3	1.80902620511161	0.0490529110763892	0.2869310280667
GO:0004659	prenyltransferase activity	6/3091	17/18639	0.352941176470588	2.12826612366072	0.0492485530591187	0.2869310280667
GO:0016018	cyclosporin A binding	6/3091	17/18639	0.352941176470588	2.12826612366072	0.0492485530591187	0.2869310280667
GO:1990226	histone methyltransferase binding	6/3091	17/18639	0.352941176470588	2.12826612366072	0.0492485530591187	0.2869310280667
GO:0140223	general transcription initiation factor activity	17/3091	68/18639	0.25	1.50752183759301	0.0493104287626839	0.2869310280667
GO:0019855	calcium channel inhibitor activity	5/3091	13/18639	0.384615384615385	2.31926436552771	0.0501386210567181	0.2869310280667
GO:0046974	histone H3K9 methyltransferase activity	5/3091	13/18639	0.384615384615385	2.31926436552771	0.0501386210567181	0.2869310280667
GO:0046975	histone H3K36 methyltransferase activity	5/3091	13/18639	0.384615384615385	2.31926436552771	0.0501386210567181	0.2869310280667
GO:0001223	transcription coactivator binding	12/3091	44/18639	0.272727272727273	1.64456927737419	0.0503781796345041	0.2869310280667
GO:0005004	GPI-linked ephrin receptor activity	13/3091	49/18639	0.26530612244898	1.59981909295585	0.0523097335783138	0.2869310280667
GO:0005008	hepatocyte growth factor receptor activity	13/3091	49/18639	0.26530612244898	1.59981909295585	0.0523097335783138	0.2869310280667
GO:0005009	insulin receptor activity	13/3091	49/18639	0.26530612244898	1.59981909295585	0.0523097335783138	0.2869310280667
GO:0005011	macrophage colony-stimulating factor receptor activity	13/3091	49/18639	0.26530612244898	1.59981909295585	0.0523097335783138	0.2869310280667
GO:0005018	platelet-derived growth factor alpha-receptor activity	13/3091	49/18639	0.26530612244898	1.59981909295585	0.0523097335783138	0.2869310280667
GO:0005020	stem cell factor receptor activity	13/3091	49/18639	0.26530612244898	1.59981909295585	0.0523097335783138	0.2869310280667
GO:0008288	boss receptor activity	13/3091	49/18639	0.26530612244898	1.59981909295585	0.0523097335783138	0.2869310280667
GO:0036332	placental growth factor receptor activity	13/3091	49/18639	0.26530612244898	1.59981909295585	0.0523097335783138	0.2869310280667
GO:0038062	protein tyrosine kinase collagen receptor activity	13/3091	49/18639	0.26530612244898	1.59981909295585	0.0523097335783138	0.2869310280667
GO:0060175	brain-derived neurotrophic factor receptor activity	13/3091	49/18639	0.26530612244898	1.59981909295585	0.0523097335783138	0.2869310280667
GO:0140566	histone reader activity	10/3091	35/18639	0.285714285714286	1.7228821001063	0.0532664776677086	0.290951348605131
GO:0004529	DNA exonuclease activity	8/3091	26/18639	0.307692307692308	1.85541149242217	0.0539727409311852	0.291139266433779
GO:0008143	poly(A) binding	8/3091	26/18639	0.307692307692308	1.85541149242217	0.0539727409311852	0.291139266433779
GO:0008198	ferrous iron binding	8/3091	26/18639	0.307692307692308	1.85541149242217	0.0539727409311852	0.291139266433779
GO:0004527	exonuclease activity	20/3091	84/18639	0.238095238095238	1.43573508342192	0.0555264335546435	0.297042151486799
GO:0008080	N-acetyltransferase activity	17/3091	69/18639	0.246376811594203	1.4856736950192	0.0556974206486167	0.297042151486799
GO:0008186	ATP-dependent activity, acting on RNA	19/3091	79/18639	0.240506329113924	1.45027417287429	0.0557525268944454	0.297042151486799
GO:0070325	lipoprotein particle receptor binding	9/3091	31/18639	0.290322580645161	1.75067052107576	0.0593171151359948	0.31361024546663
GO:0003924	GTPase activity	66/3091	331/18639	0.199395770392749	1.20237391276301	0.0593447079883008	0.31361024546663
GO:0008276	protein methyltransferase activity	22/3091	95/18639	0.231578947368421	1.39644128113879	0.0604621114543372	0.318221639233353
GO:0048306	calcium-dependent protein binding	19/3091	80/18639	0.2375	1.43214574571336	0.0621866271004398	0.324669289108626
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	15/3091	60/18639	0.25	1.50752183759301	0.0621866561446522	0.324669289108626
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	6/3091	18/18639	0.333333333333333	2.01002911679068	0.0638449289293835	0.331993630432794
GO:0008013	beta-catenin binding	24/3091	106/18639	0.226415094339623	1.36530279631065	0.0646016835559003	0.334590392919006
GO:0004364	glutathione transferase activity	8/3091	27/18639	0.296296296296296	1.78669254825838	0.065961059072338	0.335250703273912
GO:0030983	mismatched DNA binding	5/3091	14/18639	0.357142857142857	2.15360262513287	0.0676638909046036	0.335250703273912
GO:0032036	myosin heavy chain binding	5/3091	14/18639	0.357142857142857	2.15360262513287	0.0676638909046036	0.335250703273912
GO:0098847	sequence-specific single stranded DNA binding	5/3091	14/18639	0.357142857142857	2.15360262513287	0.0676638909046036	0.335250703273912
GO:0005522	profilin binding	4/3091	10/18639	0.4	2.41203494014882	0.0685974515929697	0.335250703273912
GO:0005528	FK506 binding	4/3091	10/18639	0.4	2.41203494014882	0.0685974515929697	0.335250703273912
GO:0008641	ubiquitin-like modifier activating enzyme activity	4/3091	10/18639	0.4	2.41203494014882	0.0685974515929697	0.335250703273912
GO:0015643	toxic substance binding	4/3091	10/18639	0.4	2.41203494014882	0.0685974515929697	0.335250703273912
GO:0016868	intramolecular phosphotransferase activity	4/3091	10/18639	0.4	2.41203494014882	0.0685974515929697	0.335250703273912
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	4/3091	10/18639	0.4	2.41203494014882	0.0685974515929697	0.335250703273912
GO:0033204	ribonuclease P RNA binding	4/3091	10/18639	0.4	2.41203494014882	0.0685974515929697	0.335250703273912
GO:0043295	glutathione binding	4/3091	10/18639	0.4	2.41203494014882	0.0685974515929697	0.335250703273912
GO:0051880	G-quadruplex DNA binding	4/3091	10/18639	0.4	2.41203494014882	0.0685974515929697	0.335250703273912
GO:0097177	mitochondrial ribosome binding	4/3091	10/18639	0.4	2.41203494014882	0.0685974515929697	0.335250703273912
GO:0098505	G-rich strand telomeric DNA binding	4/3091	10/18639	0.4	2.41203494014882	0.0685974515929697	0.335250703273912
GO:0005030	neurotrophin receptor activity	13/3091	51/18639	0.254901960784314	1.53708108931052	0.0692106614253117	0.336980748512754
GO:0019212	phosphatase inhibitor activity	14/3091	56/18639	0.25	1.50752183759301	0.0699747073533564	0.339429550594639
GO:0070717	poly-purine tract binding	9/3091	32/18639	0.28125	1.69596206729214	0.0708601237510657	0.342446694707753
GO:0003887	DNA-directed DNA polymerase activity	7/3091	23/18639	0.304347826086957	1.83524397620019	0.0731507776854368	0.350907789634937
GO:0031681	G-protein beta-subunit binding	7/3091	23/18639	0.304347826086957	1.83524397620019	0.0731507776854368	0.350907789634937
GO:0015399	primary active transmembrane transporter activity	35/3091	166/18639	0.210843373493976	1.27140395941579	0.0750777697757251	0.35882757613398
GO:1901681	sulfur compound binding	55/3091	275/18639	0.2	1.20601747007441	0.0755603618075199	0.359811246702476
GO:0004520	DNA endonuclease activity	11/3091	42/18639	0.261904761904762	1.57930859176411	0.0765675273843629	0.361955583998806
GO:0031492	nucleosomal DNA binding	11/3091	42/18639	0.261904761904762	1.57930859176411	0.0765675273843629	0.361955583998806
GO:0003724	RNA helicase activity	18/3091	77/18639	0.233766233766234	1.40963080917788	0.0774600649299144	0.364848131916263
GO:0045499	chemorepellent activity	8/3091	28/18639	0.285714285714286	1.7228821001063	0.0794644385994628	0.370264409244809
GO:0046875	ephrin receptor binding	8/3091	28/18639	0.285714285714286	1.7228821001063	0.0794644385994628	0.370264409244809
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	8/3091	28/18639	0.285714285714286	1.7228821001063	0.0794644385994628	0.370264409244809
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	9/3091	33/18639	0.272727272727273	1.64456927737419	0.0837015424822943	0.388614304382081
GO:0003777	microtubule motor activity	16/3091	68/18639	0.235294117647059	1.41884408244048	0.087883705612653	0.402075549960542
GO:0000774	adenyl-nucleotide exchange factor activity	5/3091	15/18639	0.333333333333333	2.01002911679068	0.0881339706593851	0.402075549960542
GO:0005523	tropomyosin binding	5/3091	15/18639	0.333333333333333	2.01002911679068	0.0881339706593851	0.402075549960542
GO:0016846	carbon-sulfur lyase activity	5/3091	15/18639	0.333333333333333	2.01002911679068	0.0881339706593851	0.402075549960542
GO:0048156	tau protein binding	11/3091	43/18639	0.255813953488372	1.5425804849789	0.0881473321067342	0.402075549960542
GO:0034212	protein N-acetyltransferase activity	13/3091	53/18639	0.245283018867925	1.47907802933654	0.0893305056844667	0.404632952577724
GO:0038064	collagen receptor activity	13/3091	53/18639	0.245283018867925	1.47907802933654	0.0893305056844667	0.404632952577724
GO:0004860	protein kinase inhibitor activity	19/3091	84/18639	0.226190476190476	1.36394832925082	0.092961442258756	0.414656871667552
GO:0003774	cytoskeletal motor activity	32/3091	153/18639	0.209150326797386	1.2611947399471	0.0931836234182433	0.414656871667552
GO:0005536	D-glucose binding	4/3091	11/18639	0.363636363636364	2.19275903649893	0.0940952131860982	0.414656871667552
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	4/3091	11/18639	0.363636363636364	2.19275903649893	0.0940952131860982	0.414656871667552
GO:0032404	mismatch repair complex binding	4/3091	11/18639	0.363636363636364	2.19275903649893	0.0940952131860982	0.414656871667552
GO:0034056	estrogen response element binding	4/3091	11/18639	0.363636363636364	2.19275903649893	0.0940952131860982	0.414656871667552
GO:0048185	activin binding	4/3091	11/18639	0.363636363636364	2.19275903649893	0.0940952131860982	0.414656871667552
GO:1900750	oligopeptide binding	4/3091	11/18639	0.363636363636364	2.19275903649893	0.0940952131860982	0.414656871667552
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	9/3091	34/18639	0.264705882352941	1.59619959274554	0.0978444127062188	0.428275207131598
GO:0090482	vitamin transmembrane transporter activity	9/3091	34/18639	0.264705882352941	1.59619959274554	0.0978444127062188	0.428275207131598
GO:0031418	L-ascorbic acid binding	6/3091	20/18639	0.3	1.80902620511161	0.0997996889704163	0.434101409133671
GO:0019210	kinase inhibitor activity	20/3091	90/18639	0.222222222222222	1.34001941119379	0.0998433241007444	0.434101409133671
GO:0050661	NADP binding	13/3091	54/18639	0.240740740740741	1.45168769545994	0.100622132037559	0.434550883661608
GO:0140463	chromatin-protein adaptor activity	13/3091	54/18639	0.240740740740741	1.45168769545994	0.100622132037559	0.434550883661608
GO:0001222	transcription corepressor binding	12/3091	49/18639	0.244897959183673	1.4767560858054	0.100949512973697	0.434550883661608
GO:0031406	carboxylic acid binding	38/3091	187/18639	0.203208556149733	1.22536534392587	0.101972000875622	0.437503634119831
GO:0003725	double-stranded RNA binding	17/3091	75/18639	0.226666666666667	1.36681979941766	0.106038374027353	0.453453573143285
GO:0016407	acetyltransferase activity	21/3091	96/18639	0.21875	1.31908160789389	0.106415581963652	0.453574611648354
GO:0019211	phosphatase activator activity	7/3091	25/18639	0.28	1.68842445810417	0.10684654051295	0.453923211329527
GO:0016278	lysine N-methyltransferase activity	16/3091	70/18639	0.228571428571429	1.37830568008504	0.107960086582827	0.457159975757901
GO:0001968	fibronectin binding	8/3091	30/18639	0.266666666666667	1.60802329343255	0.11100768673166	0.465516105648897
GO:0008187	poly-pyrimidine tract binding	8/3091	30/18639	0.266666666666667	1.60802329343255	0.11100768673166	0.465516105648897
GO:0051721	protein phosphatase 2A binding	8/3091	30/18639	0.266666666666667	1.60802329343255	0.11100768673166	0.465516105648897
GO:0008142	oxysterol binding	5/3091	16/18639	0.3125	1.88440229699127	0.111422403416956	0.465752811710748
GO:0061791	GTPase motor activity	10/3091	40/18639	0.25	1.50752183759301	0.11425381768783	0.474536622984597
GO:1990606	membrane scission GTPase motor activity	10/3091	40/18639	0.25	1.50752183759301	0.11425381768783	0.474536622984597
GO:0043177	organic acid binding	38/3091	189/18639	0.201058201058201	1.21239851488962	0.114690237335159	0.474832192788873
GO:1904047	S-adenosyl-L-methionine binding	6/3091	21/18639	0.285714285714286	1.7228821001063	0.121038648397955	0.499524580689971
GO:0004526	ribonuclease P activity	4/3091	12/18639	0.333333333333333	2.01002911679068	0.123344648458986	0.499526613696829
GO:0005095	GTPase inhibitor activity	4/3091	12/18639	0.333333333333333	2.01002911679068	0.123344648458986	0.499526613696829
GO:0005527	macrolide binding	4/3091	12/18639	0.333333333333333	2.01002911679068	0.123344648458986	0.499526613696829
GO:0017166	vinculin binding	4/3091	12/18639	0.333333333333333	2.01002911679068	0.123344648458986	0.499526613696829
GO:0043047	single-stranded telomeric DNA binding	4/3091	12/18639	0.333333333333333	2.01002911679068	0.123344648458986	0.499526613696829
GO:0045295	gamma-catenin binding	4/3091	12/18639	0.333333333333333	2.01002911679068	0.123344648458986	0.499526613696829
GO:0097602	cullin family protein binding	7/3091	26/18639	0.269230769230769	1.6234850558694	0.126326361411495	0.510013260356968
GO:0030291	protein serine/threonine kinase inhibitor activity	11/3091	46/18639	0.239130434782609	1.44197740987158	0.128913784393078	0.515948063929305
GO:0004857	enzyme inhibitor activity	78/3091	416/18639	0.1875	1.13064137819476	0.128952345854687	0.515948063929305
GO:0072349	modified amino acid transmembrane transporter activity	8/3091	31/18639	0.258064516129032	1.55615157428956	0.128987015982326	0.515948063929305
GO:0061650	ubiquitin-like protein conjugating enzyme activity	10/3091	41/18639	0.24390243902439	1.47075301228587	0.129821635585952	0.517693638839687
GO:0042054	histone methyltransferase activity	15/3091	67/18639	0.223880597014925	1.35001955605344	0.133606301655422	0.531156550923696
GO:0016922	nuclear receptor binding	28/3091	137/18639	0.204379562043796	1.23242661175487	0.136045599994747	0.539205121930398
GO:0004029	aldehyde dehydrogenase (NAD+) activity	5/3091	17/18639	0.294117647058824	1.7735551030506	0.137328174399388	0.542634123766579
GO:0004518	nuclease activity	41/3091	209/18639	0.196172248803828	1.182935796006	0.137999002744585	0.543632435054427
GO:0016410	N-acyltransferase activity	20/3091	94/18639	0.212765957446809	1.2829973085898	0.139202544745443	0.545809647817364
GO:0016504	peptidase activator activity	13/3091	57/18639	0.228070175438596	1.37528307990941	0.13939138698105	0.545809647817364
GO:0140784	metal ion sensor activity	6/3091	22/18639	0.272727272727273	1.64456927737419	0.144295711094495	0.5621367562813
GO:0042826	histone deacetylase binding	26/3091	127/18639	0.204724409448819	1.23450607172971	0.144425905075349	0.5621367562813
GO:0008307	structural constituent of muscle	10/3091	42/18639	0.238095238095238	1.43573508342192	0.146463544398949	0.563795536468413
GO:0051879	Hsp90 protein binding	10/3091	42/18639	0.238095238095238	1.43573508342192	0.146463544398949	0.563795536468413
GO:0030145	manganese ion binding	15/3091	68/18639	0.220588235294118	1.33016632728795	0.146546659026017	0.563795536468413
GO:0051117	ATPase binding	18/3091	84/18639	0.214285714285714	1.29216157507972	0.147258982691803	0.563795536468413
GO:0008266	poly(U) RNA binding	7/3091	27/18639	0.259259259259259	1.56335597972609	0.1474542172302	0.563795536468413
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	7/3091	27/18639	0.259259259259259	1.56335597972609	0.1474542172302	0.563795536468413
GO:0031369	translation initiation factor binding	8/3091	32/18639	0.25	1.50752183759301	0.14836264672608	0.563951581122526
GO:0140142	nucleocytoplasmic carrier activity	8/3091	32/18639	0.25	1.50752183759301	0.14836264672608	0.563951581122526
GO:0008408	3'-5' exonuclease activity	13/3091	58/18639	0.224137931034483	1.3515713026696	0.153900001643647	0.578985310940297
GO:0002161	aminoacyl-tRNA editing activity	4/3091	13/18639	0.307692307692308	1.85541149242217	0.155880660637772	0.578985310940297
GO:0004535	poly(A)-specific ribonuclease activity	4/3091	13/18639	0.307692307692308	1.85541149242217	0.155880660637772	0.578985310940297
GO:0005172	vascular endothelial growth factor receptor binding	4/3091	13/18639	0.307692307692308	1.85541149242217	0.155880660637772	0.578985310940297
GO:0009982	pseudouridine synthase activity	4/3091	13/18639	0.307692307692308	1.85541149242217	0.155880660637772	0.578985310940297
GO:0019104	DNA N-glycosylase activity	4/3091	13/18639	0.307692307692308	1.85541149242217	0.155880660637772	0.578985310940297
GO:0043560	insulin receptor substrate binding	4/3091	13/18639	0.307692307692308	1.85541149242217	0.155880660637772	0.578985310940297
GO:0070700	BMP receptor binding	4/3091	13/18639	0.307692307692308	1.85541149242217	0.155880660637772	0.578985310940297
GO:0016279	protein-lysine N-methyltransferase activity	15/3091	69/18639	0.217391304347826	1.31088855442871	0.160142864327294	0.593121719730719
GO:0032266	phosphatidylinositol-3-phosphate binding	11/3091	48/18639	0.229166666666667	1.38189501779359	0.160937714792021	0.594372242129621
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	10/3091	43/18639	0.232558139534884	1.40234589543536	0.164135123881438	0.601307959369293
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	5/3091	18/18639	0.277777777777778	1.67502426399224	0.165590961118621	0.601307959369293
GO:0016854	racemase and epimerase activity	5/3091	18/18639	0.277777777777778	1.67502426399224	0.165590961118621	0.601307959369293
GO:0070628	proteasome binding	5/3091	18/18639	0.277777777777778	1.67502426399224	0.165590961118621	0.601307959369293
GO:1901611	phosphatidylglycerol binding	5/3091	18/18639	0.277777777777778	1.67502426399224	0.165590961118621	0.601307959369293
GO:1990381	ubiquitin-specific protease binding	5/3091	18/18639	0.277777777777778	1.67502426399224	0.165590961118621	0.601307959369293
GO:0001786	phosphatidylserine binding	13/3091	59/18639	0.220338983050847	1.32866331448876	0.169163102427554	0.608362966489923
GO:0019003	GDP binding	16/3091	75/18639	0.213333333333333	1.28641863474604	0.16922976176702	0.608362966489923
GO:0008171	O-methyltransferase activity	6/3091	23/18639	0.260869565217391	1.57306626531445	0.169405687591809	0.608362966489923
GO:0070577	lysine-acetylated histone binding	6/3091	23/18639	0.260869565217391	1.57306626531445	0.169405687591809	0.608362966489923
GO:0001046	core promoter sequence-specific DNA binding	10/3091	44/18639	0.227272727272727	1.37047439781183	0.182781616317897	0.654589810504867
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	13/3091	60/18639	0.216666666666667	1.30651892591394	0.185149070767769	0.661246681313462
GO:0030332	cyclin binding	8/3091	34/18639	0.235294117647059	1.41884408244048	0.190964903892667	0.664485505589176
GO:0008474	palmitoyl-(protein) hydrolase activity	4/3091	14/18639	0.285714285714286	1.7228821001063	0.19116736853104	0.664485505589176
GO:0016530	metallochaperone activity	4/3091	14/18639	0.285714285714286	1.7228821001063	0.19116736853104	0.664485505589176
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	4/3091	14/18639	0.285714285714286	1.7228821001063	0.19116736853104	0.664485505589176
GO:0034236	protein kinase A catalytic subunit binding	4/3091	14/18639	0.285714285714286	1.7228821001063	0.19116736853104	0.664485505589176
GO:0042813	Wnt receptor activity	4/3091	14/18639	0.285714285714286	1.7228821001063	0.19116736853104	0.664485505589176
GO:0044548	S100 protein binding	4/3091	14/18639	0.285714285714286	1.7228821001063	0.19116736853104	0.664485505589176
GO:0098599	palmitoyl hydrolase activity	4/3091	14/18639	0.285714285714286	1.7228821001063	0.19116736853104	0.664485505589176
GO:1901612	cardiolipin binding	4/3091	14/18639	0.285714285714286	1.7228821001063	0.19116736853104	0.664485505589176
GO:1990825	sequence-specific mRNA binding	4/3091	14/18639	0.285714285714286	1.7228821001063	0.19116736853104	0.664485505589176
GO:0043236	laminin binding	7/3091	29/18639	0.241379310344828	1.45553832595187	0.194181906085204	0.671120249337403
GO:0043395	heparan sulfate proteoglycan binding	5/3091	19/18639	0.263157894736842	1.58686509220317	0.195906668615913	0.671120249337403
GO:0046527	glucosyltransferase activity	5/3091	19/18639	0.263157894736842	1.58686509220317	0.195906668615913	0.671120249337403
GO:0050145	nucleoside monophosphate kinase activity	5/3091	19/18639	0.263157894736842	1.58686509220317	0.195906668615913	0.671120249337403
GO:0005540	hyaluronic acid binding	6/3091	24/18639	0.25	1.50752183759301	0.196173611344779	0.671120249337403
GO:0140033	acetylation-dependent protein binding	6/3091	24/18639	0.25	1.50752183759301	0.196173611344779	0.671120249337403
GO:0016651	oxidoreductase activity, acting on NAD(P)H	18/3091	88/18639	0.204545454545455	1.23342695803065	0.19901615638585	0.679057751447784
GO:0004715	non-membrane spanning protein tyrosine kinase activity	10/3091	45/18639	0.222222222222222	1.34001941119379	0.202338938303079	0.688588009931944
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	9/3091	40/18639	0.225	1.35676965383371	0.208201204153493	0.703017052985821
GO:0030331	nuclear estrogen receptor binding	9/3091	40/18639	0.225	1.35676965383371	0.208201204153493	0.703017052985821
GO:0071949	FAD binding	9/3091	40/18639	0.225	1.35676965383371	0.208201204153493	0.703017052985821
GO:0051020	GTPase binding	58/3091	315/18639	0.184126984126984	1.11030179784628	0.209013115272672	0.703930180970137
GO:0016500	protein-hormone receptor activity	14/3091	67/18639	0.208955223880597	1.26001825231655	0.211711052089836	0.711174076787562
GO:0000175	3'-5'-RNA exonuclease activity	8/3091	35/18639	0.228571428571429	1.37830568008504	0.213984064639119	0.713280215463729
GO:0034061	DNA polymerase activity	8/3091	35/18639	0.228571428571429	1.37830568008504	0.213984064639119	0.713280215463729
GO:0061631	ubiquitin conjugating enzyme activity	8/3091	35/18639	0.228571428571429	1.37830568008504	0.213984064639119	0.713280215463729
GO:0033218	amide binding	46/3091	247/18639	0.186234817813765	1.12301221909763	0.215053171897256	0.715010545949955
GO:0043539	protein serine/threonine kinase activator activity	15/3091	73/18639	0.205479452054795	1.239059044597	0.220619175651413	0.722082939416328
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/3091	10/18639	0.3	1.80902620511161	0.222417982913692	0.722082939416328
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/3091	10/18639	0.3	1.80902620511161	0.222417982913692	0.722082939416328
GO:0016427	tRNA (cytidine) methyltransferase activity	3/3091	10/18639	0.3	1.80902620511161	0.222417982913692	0.722082939416328
GO:0019911	structural constituent of myelin sheath	3/3091	10/18639	0.3	1.80902620511161	0.222417982913692	0.722082939416328
GO:0031434	mitogen-activated protein kinase kinase binding	3/3091	10/18639	0.3	1.80902620511161	0.222417982913692	0.722082939416328
GO:0035374	chondroitin sulfate binding	3/3091	10/18639	0.3	1.80902620511161	0.222417982913692	0.722082939416328
GO:0099122	RNA polymerase II C-terminal domain binding	3/3091	10/18639	0.3	1.80902620511161	0.222417982913692	0.722082939416328
GO:0140999	histone H3K4 trimethyltransferase activity	3/3091	10/18639	0.3	1.80902620511161	0.222417982913692	0.722082939416328
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	10/3091	46/18639	0.217391304347826	1.31088855442871	0.22273481438919	0.722082939416328
GO:0017025	TBP-class protein binding	6/3091	25/18639	0.24	1.44722096408929	0.224382160028515	0.725613950340969
GO:0052745	inositol phosphate phosphatase activity	5/3091	20/18639	0.25	1.50752183759301	0.227942328497744	0.728490873201085
GO:0004129	cytochrome-c oxidase activity	4/3091	15/18639	0.266666666666667	1.60802329343255	0.228634058666187	0.728490873201085
GO:0008252	nucleotidase activity	4/3091	15/18639	0.266666666666667	1.60802329343255	0.228634058666187	0.728490873201085
GO:0042809	nuclear vitamin D receptor binding	4/3091	15/18639	0.266666666666667	1.60802329343255	0.228634058666187	0.728490873201085
GO:0050780	dopamine receptor binding	4/3091	15/18639	0.266666666666667	1.60802329343255	0.228634058666187	0.728490873201085
GO:0140776	protein-containing complex destabilizing activity	4/3091	15/18639	0.266666666666667	1.60802329343255	0.228634058666187	0.728490873201085
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	9/3091	41/18639	0.219512195121951	1.32367771105728	0.230245457813114	0.730046573553776
GO:0042169	SH2 domain binding	9/3091	41/18639	0.219512195121951	1.32367771105728	0.230245457813114	0.730046573553776
GO:0005080	protein kinase C binding	11/3091	52/18639	0.211538461538462	1.27559540104024	0.235189958815128	0.743909845400649
GO:0140789	histone phosphatase activity	26/3091	136/18639	0.191176470588235	1.15281081698289	0.243416448411723	0.765838157991979
GO:0035173	histone kinase activity	65/3091	360/18639	0.180555555555556	1.08876577159495	0.24358146614989	0.765838157991979
GO:0061733	protein-lysine-acetyltransferase activity	10/3091	47/18639	0.212765957446809	1.2829973085898	0.243889998006676	0.765838157991979
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	63/3091	349/18639	0.180515759312321	1.08852579677203	0.24817127058723	0.777403980152769
GO:0019209	kinase activator activity	28/3091	148/18639	0.189189189189189	1.14082733655687	0.251498389697861	0.778098955818586
GO:0004402	histone acetyltransferase activity	9/3091	42/18639	0.214285714285714	1.29216157507972	0.253095070562432	0.778098955818586
GO:0048487	beta-tubulin binding	9/3091	42/18639	0.214285714285714	1.29216157507972	0.253095070562432	0.778098955818586
GO:0030507	spectrin binding	6/3091	26/18639	0.230769230769231	1.39155861931663	0.253798899613621	0.778098955818586
GO:0050681	nuclear androgen receptor binding	6/3091	26/18639	0.230769230769231	1.39155861931663	0.253798899613621	0.778098955818586
GO:0004864	protein phosphatase inhibitor activity	11/3091	53/18639	0.207547169811321	1.25152756328476	0.255539685664429	0.778098955818586
GO:0051018	protein kinase A binding	11/3091	53/18639	0.207547169811321	1.25152756328476	0.255539685664429	0.778098955818586
GO:0001618	virus receptor activity	16/3091	81/18639	0.197530864197531	1.19112836550559	0.261347645517694	0.778098955818586
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	5/3091	21/18639	0.238095238095238	1.43573508342192	0.261349728528929	0.778098955818586
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5/3091	21/18639	0.238095238095238	1.43573508342192	0.261349728528929	0.778098955818586
GO:0015174	basic amino acid transmembrane transporter activity	5/3091	21/18639	0.238095238095238	1.43573508342192	0.261349728528929	0.778098955818586
GO:0019200	carbohydrate kinase activity	5/3091	21/18639	0.238095238095238	1.43573508342192	0.261349728528929	0.778098955818586
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	5/3091	21/18639	0.238095238095238	1.43573508342192	0.261349728528929	0.778098955818586
GO:0061891	calcium ion sensor activity	5/3091	21/18639	0.238095238095238	1.43573508342192	0.261349728528929	0.778098955818586
GO:0043394	proteoglycan binding	8/3091	37/18639	0.216216216216216	1.30380267035071	0.262851111038028	0.778098955818586
GO:0008170	N-methyltransferase activity	19/3091	98/18639	0.193877551020408	1.16909856792927	0.264079614421564	0.778098955818586
GO:0008201	heparin binding	32/3091	172/18639	0.186046511627907	1.12187671634829	0.265342373106203	0.778098955818586
GO:0016879	ligase activity, forming carbon-nitrogen bonds	10/3091	48/18639	0.208333333333333	1.25626819799418	0.26571954622106	0.778098955818586
GO:0008296	3'-5'-DNA exonuclease activity	4/3091	16/18639	0.25	1.50752183759301	0.267704610415931	0.778098955818586
GO:0015378	sodium:chloride symporter activity	4/3091	16/18639	0.25	1.50752183759301	0.267704610415931	0.778098955818586
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/3091	16/18639	0.25	1.50752183759301	0.267704610415931	0.778098955818586
GO:0016722	oxidoreductase activity, acting on metal ions	4/3091	16/18639	0.25	1.50752183759301	0.267704610415931	0.778098955818586
GO:0043023	ribosomal large subunit binding	4/3091	16/18639	0.25	1.50752183759301	0.267704610415931	0.778098955818586
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/3091	11/18639	0.272727272727273	1.64456927737419	0.270539021561539	0.778098955818586
GO:0002162	dystroglycan binding	3/3091	11/18639	0.272727272727273	1.64456927737419	0.270539021561539	0.778098955818586
GO:0004523	RNA-DNA hybrid ribonuclease activity	3/3091	11/18639	0.272727272727273	1.64456927737419	0.270539021561539	0.778098955818586
GO:0008432	JUN kinase binding	3/3091	11/18639	0.272727272727273	1.64456927737419	0.270539021561539	0.778098955818586
GO:0010854	adenylate cyclase regulator activity	3/3091	11/18639	0.272727272727273	1.64456927737419	0.270539021561539	0.778098955818586
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	3/3091	11/18639	0.272727272727273	1.64456927737419	0.270539021561539	0.778098955818586
GO:0015217	ADP transmembrane transporter activity	3/3091	11/18639	0.272727272727273	1.64456927737419	0.270539021561539	0.778098955818586
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	3/3091	11/18639	0.272727272727273	1.64456927737419	0.270539021561539	0.778098955818586
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	3/3091	11/18639	0.272727272727273	1.64456927737419	0.270539021561539	0.778098955818586
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	3/3091	11/18639	0.272727272727273	1.64456927737419	0.270539021561539	0.778098955818586
GO:0032050	clathrin heavy chain binding	3/3091	11/18639	0.272727272727273	1.64456927737419	0.270539021561539	0.778098955818586
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	3/3091	11/18639	0.272727272727273	1.64456927737419	0.270539021561539	0.778098955818586
GO:0045294	alpha-catenin binding	3/3091	11/18639	0.272727272727273	1.64456927737419	0.270539021561539	0.778098955818586
GO:0050998	nitric-oxide synthase binding	3/3091	11/18639	0.272727272727273	1.64456927737419	0.270539021561539	0.778098955818586
GO:0140098	catalytic activity, acting on RNA	69/3091	387/18639	0.178294573643411	1.07513185316711	0.272149292707217	0.781002385252499
GO:0051213	dioxygenase activity	18/3091	93/18639	0.193548387096774	1.16711368071717	0.273970439361835	0.784496852798205
GO:0003925	G protein activity	11/3091	54/18639	0.203703703703704	1.22835112692764	0.276465378446242	0.789901081274977
GO:0140272	exogenous protein binding	16/3091	82/18639	0.195121951219512	1.17660240982869	0.278286868463203	0.793361686408255
GO:0030295	protein kinase activator activity	26/3091	139/18639	0.18705035971223	1.12793000798326	0.281760110214039	0.801505783978668
GO:0005385	zinc ion transmembrane transporter activity	6/3091	27/18639	0.222222222222222	1.34001941119379	0.284183094580312	0.806633237891716
GO:0005109	frizzled binding	8/3091	38/18639	0.210526315789474	1.26949207376254	0.288431707277877	0.815133085785305
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	8/3091	38/18639	0.210526315789474	1.26949207376254	0.288431707277877	0.815133085785305
GO:1902936	phosphatidylinositol bisphosphate binding	21/3091	111/18639	0.189189189189189	1.14082733655687	0.289304398545649	0.815825852731764
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	16/3091	83/18639	0.192771084337349	1.16242647718015	0.295583113490162	0.825130032039024
GO:0030165	PDZ domain binding	16/3091	83/18639	0.192771084337349	1.16242647718015	0.295583113490162	0.825130032039024
GO:0008093	cytoskeletal anchor activity	5/3091	22/18639	0.227272727272727	1.37047439781183	0.295777380715527	0.825130032039024
GO:0030021	extracellular matrix structural constituent conferring compression resistance	5/3091	22/18639	0.227272727272727	1.37047439781183	0.295777380715527	0.825130032039024
GO:0070034	telomerase RNA binding	5/3091	22/18639	0.227272727272727	1.37047439781183	0.295777380715527	0.825130032039024
GO:0004721	phosphoprotein phosphatase activity	32/3091	175/18639	0.182857142857143	1.10264454406803	0.300618399906038	0.835497642049007
GO:0016790	thiolester hydrolase activity	9/3091	44/18639	0.204545454545455	1.23342695803065	0.300779151137643	0.835497642049007
GO:0005200	structural constituent of cytoskeleton	21/3091	112/18639	0.1875	1.13064137819476	0.304343274977392	0.842455932520688
GO:0015026	coreceptor activity	12/3091	61/18639	0.19672131147541	1.18624669187647	0.306303170184628	0.842455932520688
GO:0004549	tRNA-specific ribonuclease activity	4/3091	17/18639	0.235294117647059	1.41884408244048	0.307820436882559	0.842455932520688
GO:0004550	nucleoside diphosphate kinase activity	4/3091	17/18639	0.235294117647059	1.41884408244048	0.307820436882559	0.842455932520688
GO:0005092	GDP-dissociation inhibitor activity	4/3091	17/18639	0.235294117647059	1.41884408244048	0.307820436882559	0.842455932520688
GO:0017110	nucleoside diphosphate phosphatase activity	4/3091	17/18639	0.235294117647059	1.41884408244048	0.307820436882559	0.842455932520688
GO:0032977	membrane insertase activity	4/3091	17/18639	0.235294117647059	1.41884408244048	0.307820436882559	0.842455932520688
GO:0140996	histone H3 kinase activity	63/3091	357/18639	0.176470588235294	1.06413306183036	0.313647751987349	0.854807829875638
GO:0050840	extracellular matrix binding	13/3091	67/18639	0.194029850746269	1.17001694857965	0.313648719115907	0.854807829875638
GO:0016776	phosphotransferase activity, phosphate group as acceptor	8/3091	39/18639	0.205128205128205	1.23694099494811	0.314591362782176	0.855583204219307
GO:0051537	2 iron, 2 sulfur cluster binding	6/3091	28/18639	0.214285714285714	1.29216157507972	0.31529189943664	0.855698265694429
GO:0008179	adenylate cyclase binding	3/3091	12/18639	0.25	1.50752183759301	0.319603812595723	0.856670013143175
GO:0008603	cAMP-dependent protein kinase regulator activity	3/3091	12/18639	0.25	1.50752183759301	0.319603812595723	0.856670013143175
GO:0016801	hydrolase activity, acting on ether bonds	3/3091	12/18639	0.25	1.50752183759301	0.319603812595723	0.856670013143175
GO:0016803	ether hydrolase activity	3/3091	12/18639	0.25	1.50752183759301	0.319603812595723	0.856670013143175
GO:0016840	carbon-nitrogen lyase activity	3/3091	12/18639	0.25	1.50752183759301	0.319603812595723	0.856670013143175
GO:0035251	UDP-glucosyltransferase activity	3/3091	12/18639	0.25	1.50752183759301	0.319603812595723	0.856670013143175
GO:0020037	heme binding	26/3091	142/18639	0.183098591549296	1.10410050077235	0.322127097421363	0.861656844954262
GO:0046915	transition metal ion transmembrane transporter activity	9/3091	45/18639	0.2	1.20601747007441	0.325389204346283	0.868595412012665
GO:0008175	tRNA methyltransferase activity	7/3091	34/18639	0.205882352941176	1.24148857213542	0.32983373842176	0.877846566218537
GO:0005158	insulin receptor binding	5/3091	23/18639	0.217391304347826	1.31088855442871	0.330880628805449	0.877846566218537
GO:0140103	catalytic activity, acting on a glycoprotein	5/3091	23/18639	0.217391304347826	1.31088855442871	0.330880628805449	0.877846566218537
GO:0005048	signal sequence binding	10/3091	51/18639	0.196078431372549	1.1823700687004	0.334346674066261	0.885235593250794
GO:0141003	histone H2AX kinase activity	62/3091	354/18639	0.175141242937853	1.05611699356799	0.338700861629107	0.894941301052518
GO:0004177	aminopeptidase activity	8/3091	40/18639	0.2	1.20601747007441	0.341188902439347	0.897865532735124
GO:0004532	RNA exonuclease activity	8/3091	40/18639	0.2	1.20601747007441	0.341188902439347	0.897865532735124
GO:0003785	actin monomer binding	6/3091	29/18639	0.206896551724138	1.24760427938732	0.34688581074571	0.907804927746214
GO:0016417	S-acyltransferase activity	6/3091	29/18639	0.206896551724138	1.24760427938732	0.34688581074571	0.907804927746214
GO:1901682	sulfur compound transmembrane transporter activity	12/3091	63/18639	0.19047619047619	1.14858806673753	0.348439785234298	0.907804927746214
GO:0008409	5'-3' exonuclease activity	4/3091	18/18639	0.222222222222222	1.34001941119379	0.34845742995797	0.907804927746214
GO:0015373	monoatomic anion:sodium symporter activity	4/3091	18/18639	0.222222222222222	1.34001941119379	0.34845742995797	0.907804927746214
GO:1901981	phosphatidylinositol phosphate binding	33/3091	185/18639	0.178378378378378	1.07563720303934	0.351840272818929	0.909557847510515
GO:0004519	endonuclease activity	23/3091	127/18639	0.181102362204724	1.09206306345321	0.356639244655167	0.909557847510515
GO:0004725	protein tyrosine phosphatase activity	18/3091	98/18639	0.183673469387755	1.10756706435405	0.357107592678939	0.909557847510515
GO:0010485	histone H4 acetyltransferase activity	7/3091	35/18639	0.2	1.20601747007441	0.35879615686742	0.909557847510515
GO:0033192	calmodulin-dependent protein phosphatase activity	15/3091	81/18639	0.185185185185185	1.11668284266149	0.363544686942516	0.909557847510515
GO:0140791	histone H2AXS140 phosphatase activity	15/3091	81/18639	0.185185185185185	1.11668284266149	0.363544686942516	0.909557847510515
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	15/3091	81/18639	0.185185185185185	1.11668284266149	0.363544686942516	0.909557847510515
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	15/3091	81/18639	0.185185185185185	1.11668284266149	0.363544686942516	0.909557847510515
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	15/3091	81/18639	0.185185185185185	1.11668284266149	0.363544686942516	0.909557847510515
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	15/3091	81/18639	0.185185185185185	1.11668284266149	0.363544686942516	0.909557847510515
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	15/3091	81/18639	0.185185185185185	1.11668284266149	0.363544686942516	0.909557847510515
GO:1990439	MAP kinase serine/threonine phosphatase activity	15/3091	81/18639	0.185185185185185	1.11668284266149	0.363544686942516	0.909557847510515
GO:0030215	semaphorin receptor binding	5/3091	24/18639	0.208333333333333	1.25626819799418	0.366329843926677	0.909557847510515
GO:0050431	transforming growth factor beta binding	5/3091	24/18639	0.208333333333333	1.25626819799418	0.366329843926677	0.909557847510515
GO:0070300	phosphatidic acid binding	5/3091	24/18639	0.208333333333333	1.25626819799418	0.366329843926677	0.909557847510515
GO:0070840	dynein complex binding	5/3091	24/18639	0.208333333333333	1.25626819799418	0.366329843926677	0.909557847510515
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/3091	13/18639	0.230769230769231	1.39155861931663	0.368720758183109	0.909557847510515
GO:0005338	nucleotide-sugar transmembrane transporter activity	3/3091	13/18639	0.230769230769231	1.39155861931663	0.368720758183109	0.909557847510515
GO:0008253	5'-nucleotidase activity	3/3091	13/18639	0.230769230769231	1.39155861931663	0.368720758183109	0.909557847510515
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3/3091	13/18639	0.230769230769231	1.39155861931663	0.368720758183109	0.909557847510515
GO:0017154	semaphorin receptor activity	3/3091	13/18639	0.230769230769231	1.39155861931663	0.368720758183109	0.909557847510515
GO:0035673	oligopeptide transmembrane transporter activity	3/3091	13/18639	0.230769230769231	1.39155861931663	0.368720758183109	0.909557847510515
GO:0039706	co-receptor binding	3/3091	13/18639	0.230769230769231	1.39155861931663	0.368720758183109	0.909557847510515
GO:0045159	myosin II binding	3/3091	13/18639	0.230769230769231	1.39155861931663	0.368720758183109	0.909557847510515
GO:0061459	L-arginine transmembrane transporter activity	3/3091	13/18639	0.230769230769231	1.39155861931663	0.368720758183109	0.909557847510515
GO:0071837	HMG box domain binding	3/3091	13/18639	0.230769230769231	1.39155861931663	0.368720758183109	0.909557847510515
GO:0097157	pre-mRNA intronic binding	3/3091	13/18639	0.230769230769231	1.39155861931663	0.368720758183109	0.909557847510515
GO:0140410	monoatomic cation:bicarbonate symporter activity	3/3091	13/18639	0.230769230769231	1.39155861931663	0.368720758183109	0.909557847510515
GO:0051219	phosphoprotein binding	17/3091	93/18639	0.182795698924731	1.10227403178844	0.371102772266319	0.913700007473892
GO:0005504	fatty acid binding	9/3091	47/18639	0.191489361702128	1.15469757773082	0.375575578928743	0.922964560694454
GO:0016769	transferase activity, transferring nitrogenous groups	6/3091	30/18639	0.2	1.20601747007441	0.378733313699153	0.92896850529981
GO:0046906	tetrapyrrole binding	27/3091	152/18639	0.177631578947368	1.07113393723714	0.380156313739271	0.930702839662998
GO:0005246	calcium channel regulator activity	10/3091	53/18639	0.188679245283019	1.13775233025888	0.381773027450464	0.931501752279048
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	15/3091	82/18639	0.182926829268293	1.1030647592144	0.382632258243855	0.931501752279048
GO:0033549	MAP kinase phosphatase activity	15/3091	82/18639	0.182926829268293	1.1030647592144	0.382632258243855	0.931501752279048
GO:0031593	polyubiquitin modification-dependent protein binding	11/3091	59/18639	0.186440677966102	1.12425357379818	0.387002786106056	0.931637058705845
GO:0036002	pre-mRNA binding	11/3091	59/18639	0.186440677966102	1.12425357379818	0.387002786106056	0.931637058705845
GO:0045309	protein phosphorylated amino acid binding	11/3091	59/18639	0.186440677966102	1.12425357379818	0.387002786106056	0.931637058705845
GO:0016755	aminoacyltransferase activity	85/3091	496/18639	0.171370967741935	1.03338190480166	0.387180666104499	0.931637058705845
GO:0003756	protein disulfide isomerase activity	4/3091	19/18639	0.210526315789474	1.26949207376254	0.389137632982518	0.931637058705845
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	4/3091	19/18639	0.210526315789474	1.26949207376254	0.389137632982518	0.931637058705845
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	4/3091	19/18639	0.210526315789474	1.26949207376254	0.389137632982518	0.931637058705845
GO:0016918	retinal binding	4/3091	19/18639	0.210526315789474	1.26949207376254	0.389137632982518	0.931637058705845
GO:0120227	acyl-CoA binding	4/3091	19/18639	0.210526315789474	1.26949207376254	0.389137632982518	0.931637058705845
GO:0019787	ubiquitin-like protein transferase activity	82/3091	479/18639	0.171189979123173	1.0322905276211	0.393876478376174	0.939882122084502
GO:0031267	small GTPase binding	49/3091	283/18639	0.173144876325088	1.04407872850965	0.394027505027734	0.939882122084502
GO:0042056	chemoattractant activity	8/3091	42/18639	0.19047619047619	1.14858806673753	0.395140568223589	0.940810876722832
GO:0005539	glycosaminoglycan binding	42/3091	242/18639	0.173553719008264	1.04654408560176	0.399095316120559	0.946307598499244
GO:0140693	molecular condensate scaffold activity	9/3091	48/18639	0.1875	1.13064137819476	0.400926971092055	0.946307598499244
GO:0008483	transaminase activity	5/3091	25/18639	0.2	1.20601747007441	0.401816764901217	0.946307598499244
GO:0015662	P-type ion transporter activity	5/3091	25/18639	0.2	1.20601747007441	0.401816764901217	0.946307598499244
GO:0017056	structural constituent of nuclear pore	5/3091	25/18639	0.2	1.20601747007441	0.401816764901217	0.946307598499244
GO:0140358	P-type transmembrane transporter activity	5/3091	25/18639	0.2	1.20601747007441	0.401816764901217	0.946307598499244
GO:0044325	transmembrane transporter binding	24/3091	136/18639	0.176470588235294	1.06413306183036	0.403972589166546	0.946891488788208
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	16/3091	89/18639	0.179775280898876	1.0840606472579	0.404542890049167	0.946891488788208
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	16/3091	89/18639	0.179775280898876	1.0840606472579	0.404542890049167	0.946891488788208
GO:0005516	calmodulin binding	36/3091	207/18639	0.173913043478261	1.04871084354296	0.405297647418027	0.946891488788208
GO:0015485	cholesterol binding	10/3091	54/18639	0.185185185185185	1.11668284266149	0.405706584042332	0.946891488788208
GO:0005347	ATP transmembrane transporter activity	3/3091	14/18639	0.214285714285714	1.29216157507972	0.4171444099064	0.970103278852094
GO:0015926	glucosidase activity	3/3091	14/18639	0.214285714285714	1.29216157507972	0.4171444099064	0.970103278852094
GO:0017018	myosin phosphatase activity	15/3091	84/18639	0.178571428571429	1.07680131256644	0.421103420658482	0.977561512242906
GO:0008200	ion channel inhibitor activity	8/3091	43/18639	0.186046511627907	1.12187671634829	0.422225659990651	0.978419532955163
GO:0140793	histone H2AXY142 phosphatase activity	16/3091	90/18639	0.177777777777778	1.07201552895503	0.423168989777794	0.978860652510911
GO:0016874	ligase activity	29/3091	167/18639	0.173652694610778	1.04714091713048	0.424453238326008	0.980087406436609
GO:0016763	pentosyltransferase activity	9/3091	49/18639	0.183673469387755	1.10756706435405	0.426305363285749	0.982618745162187
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	4/3091	20/18639	0.2	1.20601747007441	0.429436459103712	0.982865135272579
GO:0015095	magnesium ion transmembrane transporter activity	4/3091	20/18639	0.2	1.20601747007441	0.429436459103712	0.982865135272579
GO:0016004	phospholipase activator activity	4/3091	20/18639	0.2	1.20601747007441	0.429436459103712	0.982865135272579
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	4/3091	20/18639	0.2	1.20601747007441	0.429436459103712	0.982865135272579
GO:0016836	hydro-lyase activity	11/3091	61/18639	0.180327868852459	1.08739280088676	0.432487757237537	0.988109111439012
GO:0008173	RNA methyltransferase activity	12/3091	67/18639	0.17910447761194	1.08001564484275	0.434895220445885	0.989855135736901
GO:0019955	cytokine binding	25/3091	144/18639	0.173611111111111	1.04689016499515	0.435037521830478	0.989855135736901
GO:0034237	protein kinase A regulatory subunit binding	5/3091	26/18639	0.192307692307692	1.15963218276386	0.437059113779216	0.989855135736901
GO:0043548	phosphatidylinositol 3-kinase binding	5/3091	26/18639	0.192307692307692	1.15963218276386	0.437059113779216	0.989855135736901
GO:0070006	metalloaminopeptidase activity	5/3091	26/18639	0.192307692307692	1.15963218276386	0.437059113779216	0.989855135736901
GO:0046332	SMAD binding	14/3091	79/18639	0.177215189873418	1.06862307474948	0.438792131499715	0.992051775564574
GO:0043425	bHLH transcription factor binding	6/3091	32/18639	0.1875	1.13064137819476	0.442325089033594	0.998303152332764
GO:0042887	amide transmembrane transporter activity	7/3091	38/18639	0.184210526315789	1.11080556454222	0.446212431024785	1
GO:0016248	channel inhibitor activity	8/3091	44/18639	0.181818181818182	1.09637951824946	0.449213773069097	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	15/3091	86/18639	0.174418604651163	1.05175942157652	0.459657883509893	1
GO:0031490	chromatin DNA binding	22/3091	128/18639	0.171875	1.0364212633452	0.463629368614888	1
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	3/3091	15/18639	0.2	1.20601747007441	0.464271997716453	1
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	3/3091	15/18639	0.2	1.20601747007441	0.464271997716453	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	3/3091	15/18639	0.2	1.20601747007441	0.464271997716453	1
GO:0005041	low-density lipoprotein particle receptor activity	3/3091	15/18639	0.2	1.20601747007441	0.464271997716453	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/3091	15/18639	0.2	1.20601747007441	0.464271997716453	1
GO:0031005	filamin binding	3/3091	15/18639	0.2	1.20601747007441	0.464271997716453	1
GO:0045504	dynein heavy chain binding	3/3091	15/18639	0.2	1.20601747007441	0.464271997716453	1
GO:0061578	K63-linked deubiquitinase activity	3/3091	15/18639	0.2	1.20601747007441	0.464271997716453	1
GO:0120283	protein serine/threonine kinase binding	3/3091	15/18639	0.2	1.20601747007441	0.464271997716453	1
GO:0140161	monocarboxylate:sodium symporter activity	3/3091	15/18639	0.2	1.20601747007441	0.464271997716453	1
GO:0035091	phosphatidylinositol binding	48/3091	284/18639	0.169014084507042	1.01916969302063	0.467296755483405	1
GO:0010314	phosphatidylinositol-5-phosphate binding	4/3091	21/18639	0.19047619047619	1.14858806673753	0.468986278062484	1
GO:0051010	microtubule plus-end binding	4/3091	21/18639	0.19047619047619	1.14858806673753	0.468986278062484	1
GO:0072542	protein phosphatase activator activity	4/3091	21/18639	0.19047619047619	1.14858806673753	0.468986278062484	1
GO:0005044	scavenger receptor activity	5/3091	27/18639	0.185185185185185	1.11668284266149	0.471803663597149	1
GO:0030296	protein tyrosine kinase activator activity	6/3091	33/18639	0.181818181818182	1.09637951824946	0.473676643036901	1
GO:0071889	14-3-3 protein binding	6/3091	33/18639	0.181818181818182	1.09637951824946	0.473676643036901	1
GO:0140416	transcription regulator inhibitor activity	6/3091	33/18639	0.181818181818182	1.09637951824946	0.473676643036901	1
GO:0141110	transporter inhibitor activity	8/3091	45/18639	0.177777777777778	1.07201552895503	0.475986652792949	1
GO:0016597	amino acid binding	9/3091	51/18639	0.176470588235294	1.06413306183036	0.476734503790934	1
GO:0016791	phosphatase activity	46/3091	273/18639	0.168498168498169	1.01605867442166	0.478090197612755	1
GO:0016779	nucleotidyltransferase activity	23/3091	136/18639	0.169117647058824	1.0197941842541	0.49474607653422	1
GO:0032451	demethylase activity	7/3091	40/18639	0.175	1.05526528631511	0.503389674879964	1
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	7/3091	40/18639	0.175	1.05526528631511	0.503389674879964	1
GO:0050997	quaternary ammonium group binding	7/3091	40/18639	0.175	1.05526528631511	0.503389674879964	1
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	6/3091	34/18639	0.176470588235294	1.06413306183036	0.504500122597289	1
GO:0015078	proton transmembrane transporter activity	31/3091	185/18639	0.167567567567568	1.0104470695218	0.505530907489037	1
GO:0046625	sphingolipid binding	5/3091	28/18639	0.178571428571429	1.07680131256644	0.505827960153782	1
GO:0015377	chloride:monoatomic cation symporter activity	4/3091	22/18639	0.181818181818182	1.09637951824946	0.507477144139586	1
GO:0031683	G-protein beta/gamma-subunit complex binding	4/3091	22/18639	0.181818181818182	1.09637951824946	0.507477144139586	1
GO:0034062	5'-3' RNA polymerase activity	4/3091	22/18639	0.181818181818182	1.09637951824946	0.507477144139586	1
GO:0097747	RNA polymerase activity	4/3091	22/18639	0.181818181818182	1.09637951824946	0.507477144139586	1
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	3/3091	16/18639	0.1875	1.13064137819476	0.509633702478113	1
GO:0004708	MAP kinase kinase activity	3/3091	16/18639	0.1875	1.13064137819476	0.509633702478113	1
GO:0005024	transforming growth factor beta receptor activity	3/3091	16/18639	0.1875	1.13064137819476	0.509633702478113	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/3091	16/18639	0.1875	1.13064137819476	0.509633702478113	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/3091	16/18639	0.1875	1.13064137819476	0.509633702478113	1
GO:0019841	retinol binding	3/3091	16/18639	0.1875	1.13064137819476	0.509633702478113	1
GO:0022858	alanine transmembrane transporter activity	3/3091	16/18639	0.1875	1.13064137819476	0.509633702478113	1
GO:0030275	LRR domain binding	3/3091	16/18639	0.1875	1.13064137819476	0.509633702478113	1
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0004935	adrenergic receptor activity	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0005031	tumor necrosis factor receptor activity	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0005337	nucleoside transmembrane transporter activity	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0005345	purine nucleobase transmembrane transporter activity	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0008190	eukaryotic initiation factor 4E binding	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0008239	dipeptidyl-peptidase activity	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0015187	glycine transmembrane transporter activity	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0016303	1-phosphatidylinositol-3-kinase activity	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0030957	Tat protein binding	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0070097	delta-catenin binding	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0140940	histone H2A methyltransferase activity	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:1990259	histone H2AQ104 methyltransferase activity	2/3091	10/18639	0.2	1.20601747007441	0.512624143150258	1
GO:0004867	serine-type endopeptidase inhibitor activity	16/3091	95/18639	0.168421052631579	1.01559365901003	0.515793432939373	1
GO:0043495	protein-membrane adaptor activity	8/3091	47/18639	0.170212765957447	1.02639784687184	0.528456890346289	1
GO:0016877	ligase activity, forming carbon-sulfur bonds	7/3091	41/18639	0.170731707317073	1.02952710860011	0.531246667335145	1
GO:0008238	exopeptidase activity	17/3091	102/18639	0.166666666666667	1.00501455839534	0.532418695114951	1
GO:0005154	epidermal growth factor receptor binding	6/3091	35/18639	0.171428571428571	1.03372926006378	0.534645770679331	1
GO:0043015	gamma-tubulin binding	6/3091	35/18639	0.171428571428571	1.03372926006378	0.534645770679331	1
GO:0004629	phospholipase C activity	5/3091	29/18639	0.172413793103448	1.03967023282277	0.538940907947131	1
GO:0140101	catalytic activity, acting on a tRNA	23/3091	139/18639	0.165467625899281	0.997784237831346	0.540271628216903	1
GO:0005518	collagen binding	12/3091	72/18639	0.166666666666667	1.00501455839534	0.541643271363166	1
GO:0005212	structural constituent of eye lens	4/3091	23/18639	0.173913043478261	1.04871084354296	0.54465535789414	1
GO:0016493	C-C chemokine receptor activity	4/3091	23/18639	0.173913043478261	1.04871084354296	0.54465535789414	1
GO:0044013	histone H2B acetyltransferase activity	4/3091	23/18639	0.173913043478261	1.04871084354296	0.54465535789414	1
GO:0140102	catalytic activity, acting on a rRNA	4/3091	23/18639	0.173913043478261	1.04871084354296	0.54465535789414	1
GO:0004722	protein serine/threonine phosphatase activity	17/3091	103/18639	0.16504854368932	0.995257135498299	0.549851469903125	1
GO:0030169	low-density lipoprotein particle binding	3/3091	17/18639	0.176470588235294	1.06413306183036	0.552879402248589	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	3/3091	17/18639	0.176470588235294	1.06413306183036	0.552879402248589	1
GO:0031489	myosin V binding	3/3091	17/18639	0.176470588235294	1.06413306183036	0.552879402248589	1
GO:0032183	SUMO binding	3/3091	17/18639	0.176470588235294	1.06413306183036	0.552879402248589	1
GO:0038191	neuropilin binding	3/3091	17/18639	0.176470588235294	1.06413306183036	0.552879402248589	1
GO:0070402	NADPH binding	3/3091	17/18639	0.176470588235294	1.06413306183036	0.552879402248589	1
GO:0070492	oligosaccharide binding	3/3091	17/18639	0.176470588235294	1.06413306183036	0.552879402248589	1
GO:0038187	pattern recognition receptor activity	8/3091	48/18639	0.166666666666667	1.00501455839534	0.553962874197135	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	20/3091	122/18639	0.163934426229508	0.988538909897057	0.560531629081966	1
GO:0061659	ubiquitin-like protein ligase activity	61/3091	372/18639	0.163978494623656	0.988804646163158	0.5607672068925	1
GO:0004222	metalloendopeptidase activity	18/3091	110/18639	0.163636363636364	0.986741566424517	0.564725329152178	1
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0003953	NAD+ nucleosidase activity	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0004016	adenylate cyclase activity	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0008046	axon guidance receptor activity	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0008199	ferric iron binding	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0008271	secondary active sulfate transmembrane transporter activity	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0008526	phosphatidylinositol transfer activity	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0015205	nucleobase transmembrane transporter activity	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0016594	glycine binding	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0019215	intermediate filament binding	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0034713	type I transforming growth factor beta receptor binding	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0043522	leucine zipper domain binding	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0047676	arachidonate-CoA ligase activity	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0097493	structural molecule activity conferring elasticity	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0140031	phosphorylation-dependent protein binding	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/3091	11/18639	0.181818181818182	1.09637951824946	0.566420836836639	1
GO:0008237	metallopeptidase activity	30/3091	184/18639	0.16304347826087	0.98316641582153	0.571726980251638	1
GO:0140313	molecular sequestering activity	9/3091	55/18639	0.163636363636364	0.986741566424517	0.57376353880101	1
GO:0060590	ATPase regulator activity	8/3091	49/18639	0.163265306122449	0.9845040572036	0.578871656813991	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/3091	24/18639	0.166666666666667	1.00501455839534	0.580320460687634	1
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/3091	24/18639	0.166666666666667	1.00501455839534	0.580320460687634	1
GO:0004622	lysophospholipase activity	4/3091	24/18639	0.166666666666667	1.00501455839534	0.580320460687634	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	4/3091	24/18639	0.166666666666667	1.00501455839534	0.580320460687634	1
GO:0019957	C-C chemokine binding	4/3091	24/18639	0.166666666666667	1.00501455839534	0.580320460687634	1
GO:0060229	lipase activator activity	4/3091	24/18639	0.166666666666667	1.00501455839534	0.580320460687634	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	4/3091	24/18639	0.166666666666667	1.00501455839534	0.580320460687634	1
GO:0004712	protein serine/threonine/tyrosine kinase activity	7/3091	43/18639	0.162790697674419	0.981642126804752	0.58495943132878	1
GO:0032934	sterol binding	11/3091	68/18639	0.161764705882353	0.975455306677831	0.586625146119239	1
GO:0046982	protein heterodimerization activity	60/3091	369/18639	0.16260162601626	0.980502008190577	0.588998869783881	1
GO:0022829	wide pore channel activity	6/3091	37/18639	0.162162162162162	0.977852002763035	0.592403546205758	1
GO:0000900	mRNA regulatory element binding translation repressor activity	3/3091	18/18639	0.166666666666667	1.00501455839534	0.593763796706713	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	3/3091	18/18639	0.166666666666667	1.00501455839534	0.593763796706713	1
GO:0008525	phosphatidylcholine transporter activity	3/3091	18/18639	0.166666666666667	1.00501455839534	0.593763796706713	1
GO:0030228	lipoprotein particle receptor activity	3/3091	18/18639	0.166666666666667	1.00501455839534	0.593763796706713	1
GO:0034185	apolipoprotein binding	3/3091	18/18639	0.166666666666667	1.00501455839534	0.593763796706713	1
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	37/3091	229/18639	0.161572052401747	0.974293589361423	0.596999915390298	1
GO:0030971	receptor tyrosine kinase binding	13/3091	81/18639	0.160493827160494	0.967791796973292	0.59787321017933	1
GO:0008327	methyl-CpG binding	5/3091	31/18639	0.161290322580645	0.972594733930975	0.601822373789018	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	29/3091	181/18639	0.160220994475138	0.96614659204856	0.611880305853384	1
GO:0003707	nuclear steroid receptor activity	4/3091	25/18639	0.16	0.964813976059528	0.614321164646951	1
GO:0005537	D-mannose binding	4/3091	25/18639	0.16	0.964813976059528	0.614321164646951	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	4/3091	25/18639	0.16	0.964813976059528	0.614321164646951	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	4/3091	25/18639	0.16	0.964813976059528	0.614321164646951	1
GO:0047617	fatty acyl-CoA hydrolase activity	4/3091	25/18639	0.16	0.964813976059528	0.614321164646951	1
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	4/3091	25/18639	0.16	0.964813976059528	0.614321164646951	1
GO:0000995	RNA polymerase III general transcription initiation factor activity	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0004000	adenosine deaminase activity	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0004032	aldose reductase (NADPH) activity	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0004126	cytidine deaminase activity	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0004859	phospholipase inhibitor activity	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0008504	monoamine transmembrane transporter activity	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0010853	cyclase activator activity	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0015132	prostaglandin transmembrane transporter activity	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0016423	tRNA (guanine) methyltransferase activity	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0031543	peptidyl-proline dioxygenase activity	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0035497	cAMP response element binding	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0036009	protein-glutamine N-methyltransferase activity	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0070008	serine-type exopeptidase activity	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/3091	12/18639	0.166666666666667	1.00501455839534	0.615784241684823	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	21/3091	132/18639	0.159090909090909	0.95933207846828	0.619026820996991	1
GO:0015932	nucleobase-containing compound transmembrane transporter activity	9/3091	57/18639	0.157894736842105	0.952119055321902	0.619180315935035	1
GO:0005501	retinoid binding	6/3091	38/18639	0.157894736842105	0.952119055321902	0.61981438030219	1
GO:0019840	isoprenoid binding	6/3091	38/18639	0.157894736842105	0.952119055321902	0.61981438030219	1
GO:0017022	myosin binding	12/3091	76/18639	0.157894736842105	0.952119055321902	0.621639742308503	1
GO:0032182	ubiquitin-like protein binding	19/3091	120/18639	0.158333333333333	0.954763830475574	0.625635416578573	1
GO:0008378	galactosyltransferase activity	5/3091	32/18639	0.15625	0.942201148495633	0.631358908002984	1
GO:0051059	NF-kappaB binding	5/3091	32/18639	0.15625	0.942201148495633	0.631358908002984	1
GO:0071813	lipoprotein particle binding	5/3091	32/18639	0.15625	0.942201148495633	0.631358908002984	1
GO:0071814	protein-lipid complex binding	5/3091	32/18639	0.15625	0.942201148495633	0.631358908002984	1
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/3091	19/18639	0.157894736842105	0.952119055321902	0.632131202404999	1
GO:0015245	fatty acid transmembrane transporter activity	3/3091	19/18639	0.157894736842105	0.952119055321902	0.632131202404999	1
GO:0030506	ankyrin binding	3/3091	19/18639	0.157894736842105	0.952119055321902	0.632131202404999	1
GO:0070003	threonine-type peptidase activity	3/3091	19/18639	0.157894736842105	0.952119055321902	0.632131202404999	1
GO:0097001	ceramide binding	3/3091	19/18639	0.157894736842105	0.952119055321902	0.632131202404999	1
GO:1990380	K48-linked deubiquitinase activity	3/3091	19/18639	0.157894736842105	0.952119055321902	0.632131202404999	1
GO:0061134	peptidase regulator activity	36/3091	226/18639	0.15929203539823	0.960544887669884	0.63257657264228	1
GO:0004540	RNA nuclease activity	19/3091	121/18639	0.15702479338843	0.946873220306355	0.640733883678415	1
GO:0004842	ubiquitin-protein transferase activity	72/3091	449/18639	0.160356347438753	0.966962782242288	0.643711412638823	1
GO:0042578	phosphoric ester hydrolase activity	58/3091	363/18639	0.159779614325069	0.963485031188922	0.644809463699387	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	6/3091	39/18639	0.153846153846154	0.927705746211084	0.646143442229342	1
GO:0001637	G protein-coupled chemoattractant receptor activity	4/3091	26/18639	0.153846153846154	0.927705746211084	0.646550628441084	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/3091	26/18639	0.153846153846154	0.927705746211084	0.646550628441084	1
GO:0004435	phosphatidylinositol phospholipase C activity	4/3091	26/18639	0.153846153846154	0.927705746211084	0.646550628441084	1
GO:0004950	chemokine receptor activity	4/3091	26/18639	0.153846153846154	0.927705746211084	0.646550628441084	1
GO:0005160	transforming growth factor beta receptor binding	4/3091	26/18639	0.153846153846154	0.927705746211084	0.646550628441084	1
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	4/3091	26/18639	0.153846153846154	0.927705746211084	0.646550628441084	1
GO:0016289	acyl-CoA hydrolase activity	4/3091	26/18639	0.153846153846154	0.927705746211084	0.646550628441084	1
GO:0160215	deacylase activity	10/3091	65/18639	0.153846153846154	0.927705746211084	0.653878628622695	1
GO:0019956	chemokine binding	5/3091	33/18639	0.151515151515152	0.913649598541219	0.659516455318357	1
GO:0003964	RNA-directed DNA polymerase activity	2/3091	13/18639	0.153846153846154	0.927705746211084	0.660704875048771	1
GO:0005035	death receptor activity	2/3091	13/18639	0.153846153846154	0.927705746211084	0.660704875048771	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/3091	13/18639	0.153846153846154	0.927705746211084	0.660704875048771	1
GO:0070123	transforming growth factor beta receptor activity, type III	2/3091	13/18639	0.153846153846154	0.927705746211084	0.660704875048771	1
GO:0071714	icosanoid transmembrane transporter activity	2/3091	13/18639	0.153846153846154	0.927705746211084	0.660704875048771	1
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/3091	13/18639	0.153846153846154	0.927705746211084	0.660704875048771	1
GO:0140852	histone ubiquitin ligase activity	2/3091	13/18639	0.153846153846154	0.927705746211084	0.660704875048771	1
GO:0015297	antiporter activity	21/3091	135/18639	0.155555555555556	0.938013587835652	0.661758722486658	1
GO:0005506	iron ion binding	24/3091	154/18639	0.155844155844156	0.939753872785254	0.664178991780717	1
GO:0030695	GTPase regulator activity	78/3091	489/18639	0.159509202453988	0.961854423985725	0.667188939015913	1
GO:0000339	RNA cap binding	3/3091	20/18639	0.15	0.904513102555807	0.66790086298758	1
GO:0010851	cyclase regulator activity	3/3091	20/18639	0.15	0.904513102555807	0.66790086298758	1
GO:0015464	acetylcholine receptor activity	3/3091	20/18639	0.15	0.904513102555807	0.66790086298758	1
GO:0016408	C-acyltransferase activity	3/3091	20/18639	0.15	0.904513102555807	0.66790086298758	1
GO:0061608	nuclear import signal receptor activity	3/3091	20/18639	0.15	0.904513102555807	0.66790086298758	1
GO:0140939	histone H4 methyltransferase activity	3/3091	20/18639	0.15	0.904513102555807	0.66790086298758	1
GO:1901505	carbohydrate derivative transmembrane transporter activity	8/3091	53/18639	0.150943396226415	0.910201864207102	0.671268948785889	1
GO:0060589	nucleoside-triphosphatase regulator activity	78/3091	490/18639	0.159183673469388	0.95989145577351	0.674503854762814	1
GO:1990782	protein tyrosine kinase binding	18/3091	117/18639	0.153846153846154	0.927705746211084	0.674556719258697	1
GO:0002020	protease binding	21/3091	136/18639	0.154411764705882	0.931116429101566	0.675437179123658	1
GO:0004683	calcium/calmodulin-dependent protein kinase activity	4/3091	27/18639	0.148148148148148	0.893346274129192	0.676941404935682	1
GO:0008320	protein transmembrane transporter activity	4/3091	27/18639	0.148148148148148	0.893346274129192	0.676941404935682	1
GO:0035255	ionotropic glutamate receptor binding	4/3091	27/18639	0.148148148148148	0.893346274129192	0.676941404935682	1
GO:0030246	carbohydrate binding	44/3091	280/18639	0.157142857142857	0.947585155058465	0.677672806644018	1
GO:0052689	carboxylic ester hydrolase activity	14/3091	92/18639	0.152173913043478	0.917621988100094	0.680596952876899	1
GO:0004521	RNA endonuclease activity	11/3091	73/18639	0.150684931506849	0.90864329937113	0.684136131630382	1
GO:0008376	acetylgalactosaminyltransferase activity	5/3091	34/18639	0.147058823529412	0.886777551525301	0.686243409235783	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	8/3091	54/18639	0.148148148148148	0.893346274129192	0.69232722119281	1
GO:0001530	lipopolysaccharide binding	6/3091	41/18639	0.146341463414634	0.882451807371519	0.695350474873344	1
GO:0017080	sodium channel regulator activity	6/3091	41/18639	0.146341463414634	0.882451807371519	0.695350474873344	1
GO:0009975	cyclase activity	3/3091	21/18639	0.142857142857143	0.86144105005315	0.701053293808429	1
GO:0051428	peptide hormone receptor binding	3/3091	21/18639	0.142857142857143	0.86144105005315	0.701053293808429	1
GO:0004705	JUN kinase activity	2/3091	14/18639	0.142857142857143	0.86144105005315	0.701298285905833	1
GO:0005161	platelet-derived growth factor receptor binding	2/3091	14/18639	0.142857142857143	0.86144105005315	0.701298285905833	1
GO:0008331	high voltage-gated calcium channel activity	2/3091	14/18639	0.142857142857143	0.86144105005315	0.701298285905833	1
GO:0008559	ABC-type xenobiotic transporter activity	2/3091	14/18639	0.142857142857143	0.86144105005315	0.701298285905833	1
GO:0019763	immunoglobulin receptor activity	2/3091	14/18639	0.142857142857143	0.86144105005315	0.701298285905833	1
GO:0019992	diacylglycerol binding	2/3091	14/18639	0.142857142857143	0.86144105005315	0.701298285905833	1
GO:0032454	histone H3K9 demethylase activity	2/3091	14/18639	0.142857142857143	0.86144105005315	0.701298285905833	1
GO:0042043	neurexin family protein binding	2/3091	14/18639	0.142857142857143	0.86144105005315	0.701298285905833	1
GO:0046030	inositol trisphosphate phosphatase activity	2/3091	14/18639	0.142857142857143	0.86144105005315	0.701298285905833	1
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/3091	14/18639	0.142857142857143	0.86144105005315	0.701298285905833	1
GO:0071933	Arp2/3 complex binding	2/3091	14/18639	0.142857142857143	0.86144105005315	0.701298285905833	1
GO:1901474	azole transmembrane transporter activity	2/3091	14/18639	0.142857142857143	0.86144105005315	0.701298285905833	1
GO:0022804	active transmembrane transporter activity	72/3091	457/18639	0.157549234135667	0.950035643822292	0.704113476792929	1
GO:0036408	histone H3K14 acetyltransferase activity	4/3091	28/18639	0.142857142857143	0.86144105005315	0.705460312399332	1
GO:0046966	nuclear thyroid hormone receptor binding	4/3091	28/18639	0.142857142857143	0.86144105005315	0.705460312399332	1
GO:0051393	alpha-actinin binding	4/3091	28/18639	0.142857142857143	0.86144105005315	0.705460312399332	1
GO:0043130	ubiquitin binding	15/3091	100/18639	0.15	0.904513102555807	0.705616850761136	1
GO:0005343	organic acid:sodium symporter activity	5/3091	35/18639	0.142857142857143	0.86144105005315	0.711509682328524	1
GO:0019783	ubiquitin-like protein peptidase activity	19/3091	127/18639	0.149606299212598	0.902139052417866	0.724481237830084	1
GO:0005496	steroid binding	16/3091	108/18639	0.148148148148148	0.893346274129192	0.728206868123418	1
GO:0004407	histone deacetylase activity	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0005243	gap junction channel activity	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0008649	rRNA methyltransferase activity	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0032931	histone H3K56 acetyltransferase activity	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0033558	protein lysine deacetylase activity	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0033691	sialic acid binding	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0043992	histone H3K9 acetyltransferase activity	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0043993	histone H3K18 acetyltransferase activity	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0043994	histone H3K23 acetyltransferase activity	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0043999	histone H2AK5 acetyltransferase activity	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0044012	histone H2AK9 acetyltransferase activity	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0044014	histone H2BK5 acetyltransferase activity	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0044015	histone H2BK12 acetyltransferase activity	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0044016	histone H3K4 acetyltransferase activity	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0044017	histone H3K27 acetyltransferase activity	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0044018	histone H3K36 acetyltransferase activity	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0140908	histone H3K122 acetyltransferase activity	3/3091	22/18639	0.136363636363636	0.822284638687097	0.731617949019299	1
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	4/3091	29/18639	0.137931034482759	0.831736186258213	0.732103417111684	1
GO:0010484	histone H3 acetyltransferase activity	4/3091	29/18639	0.137931034482759	0.831736186258213	0.732103417111684	1
GO:0035250	UDP-galactosyltransferase activity	4/3091	29/18639	0.137931034482759	0.831736186258213	0.732103417111684	1
GO:0051861	glycolipid binding	4/3091	29/18639	0.137931034482759	0.831736186258213	0.732103417111684	1
GO:0097472	cyclin-dependent protein kinase activity	4/3091	29/18639	0.137931034482759	0.831736186258213	0.732103417111684	1
GO:0106222	lncRNA binding	4/3091	29/18639	0.137931034482759	0.831736186258213	0.732103417111684	1
GO:0005484	SNAP receptor activity	5/3091	36/18639	0.138888888888889	0.837512131996118	0.735304202592742	1
GO:0016409	palmitoyltransferase activity	5/3091	36/18639	0.138888888888889	0.837512131996118	0.735304202592742	1
GO:0044390	ubiquitin-like protein conjugating enzyme binding	5/3091	36/18639	0.138888888888889	0.837512131996118	0.735304202592742	1
GO:0004467	long-chain fatty acid-CoA ligase activity	2/3091	15/18639	0.133333333333333	0.804011646716273	0.737763868704198	1
GO:0008242	omega peptidase activity	2/3091	15/18639	0.133333333333333	0.804011646716273	0.737763868704198	1
GO:0015116	sulfate transmembrane transporter activity	2/3091	15/18639	0.133333333333333	0.804011646716273	0.737763868704198	1
GO:0033130	acetylcholine receptor binding	2/3091	15/18639	0.133333333333333	0.804011646716273	0.737763868704198	1
GO:0048531	beta-1,3-galactosyltransferase activity	2/3091	15/18639	0.133333333333333	0.804011646716273	0.737763868704198	1
GO:0051371	muscle alpha-actinin binding	2/3091	15/18639	0.133333333333333	0.804011646716273	0.737763868704198	1
GO:0141050	histone H3K deacetylase activity	2/3091	15/18639	0.133333333333333	0.804011646716273	0.737763868704198	1
GO:0141051	histone H4K deacetylase activity	2/3091	15/18639	0.133333333333333	0.804011646716273	0.737763868704198	1
GO:0015605	organophosphate ester transmembrane transporter activity	7/3091	50/18639	0.14	0.844212229052087	0.744833641796945	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	10/3091	70/18639	0.142857142857143	0.86144105005315	0.744992430467375	1
GO:0001965	G-protein alpha-subunit binding	4/3091	30/18639	0.133333333333333	0.804011646716273	0.756891261775523	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	4/3091	30/18639	0.133333333333333	0.804011646716273	0.756891261775523	1
GO:0015215	nucleotide transmembrane transporter activity	4/3091	30/18639	0.133333333333333	0.804011646716273	0.756891261775523	1
GO:0031210	phosphatidylcholine binding	4/3091	30/18639	0.133333333333333	0.804011646716273	0.756891261775523	1
GO:0033612	receptor serine/threonine kinase binding	4/3091	30/18639	0.133333333333333	0.804011646716273	0.756891261775523	1
GO:0043995	histone H4K5 acetyltransferase activity	4/3091	30/18639	0.133333333333333	0.804011646716273	0.756891261775523	1
GO:0043996	histone H4K8 acetyltransferase activity	4/3091	30/18639	0.133333333333333	0.804011646716273	0.756891261775523	1
GO:0043997	histone H4K12 acetyltransferase activity	4/3091	30/18639	0.133333333333333	0.804011646716273	0.756891261775523	1
GO:0048019	receptor antagonist activity	4/3091	30/18639	0.133333333333333	0.804011646716273	0.756891261775523	1
GO:0070566	adenylyltransferase activity	4/3091	30/18639	0.133333333333333	0.804011646716273	0.756891261775523	1
GO:0098918	structural constituent of synapse	4/3091	30/18639	0.133333333333333	0.804011646716273	0.756891261775523	1
GO:0042805	actinin binding	5/3091	37/18639	0.135135135135135	0.814876668969196	0.757632430153209	1
GO:0000295	adenine nucleotide transmembrane transporter activity	3/3091	23/18639	0.130434782608696	0.786533132657224	0.759662337688073	1
GO:0005283	amino acid:sodium symporter activity	3/3091	23/18639	0.130434782608696	0.786533132657224	0.759662337688073	1
GO:0016849	phosphorus-oxygen lyase activity	3/3091	23/18639	0.130434782608696	0.786533132657224	0.759662337688073	1
GO:0043274	phospholipase binding	3/3091	23/18639	0.130434782608696	0.786533132657224	0.759662337688073	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	3/3091	23/18639	0.130434782608696	0.786533132657224	0.759662337688073	1
GO:0099186	structural constituent of postsynapse	3/3091	23/18639	0.130434782608696	0.786533132657224	0.759662337688073	1
GO:0030547	signaling receptor inhibitor activity	6/3091	44/18639	0.136363636363636	0.822284638687097	0.760153015538704	1
GO:0043014	alpha-tubulin binding	6/3091	44/18639	0.136363636363636	0.822284638687097	0.760153015538704	1
GO:0005543	phospholipid binding	77/3091	497/18639	0.154929577464789	0.934238885268909	0.763467858594057	1
GO:0030544	Hsp70 protein binding	7/3091	51/18639	0.137254901960784	0.827659048090281	0.763639612488444	1
GO:0061630	ubiquitin protein ligase activity	54/3091	353/18639	0.152974504249292	0.92244962300309	0.764482797523378	1
GO:0005096	GTPase activator activity	41/3091	271/18639	0.151291512915129	0.91230103824817	0.764952835134709	1
GO:0000062	fatty-acyl-CoA binding	2/3091	16/18639	0.125	0.753760918796506	0.770353892450782	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/3091	16/18639	0.125	0.753760918796506	0.770353892450782	1
GO:0004707	MAP kinase activity	2/3091	16/18639	0.125	0.753760918796506	0.770353892450782	1
GO:0015562	efflux transmembrane transporter activity	2/3091	16/18639	0.125	0.753760918796506	0.770353892450782	1
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	2/3091	16/18639	0.125	0.753760918796506	0.770353892450782	1
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/3091	16/18639	0.125	0.753760918796506	0.770353892450782	1
GO:0055102	lipase inhibitor activity	2/3091	16/18639	0.125	0.753760918796506	0.770353892450782	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/3091	16/18639	0.125	0.753760918796506	0.770353892450782	1
GO:0070411	I-SMAD binding	2/3091	16/18639	0.125	0.753760918796506	0.770353892450782	1
GO:0140328	floppase activity	2/3091	16/18639	0.125	0.753760918796506	0.770353892450782	1
GO:0106310	protein serine kinase activity	55/3091	361/18639	0.152354570637119	0.918711369170257	0.776532401397974	1
GO:0035403	histone H3T6 kinase activity	37/3091	247/18639	0.149797570850202	0.903292437100266	0.776559604395911	1
GO:0043178	alcohol binding	13/3091	92/18639	0.141304347826087	0.852077560378659	0.776992709443538	1
GO:0000146	microfilament motor activity	5/3091	38/18639	0.131578947368421	0.793432546101585	0.778513952857909	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/3091	31/18639	0.129032258064516	0.77807578714478	0.779864430366117	1
GO:0005452	solute:inorganic anion antiporter activity	4/3091	31/18639	0.129032258064516	0.77807578714478	0.779864430366117	1
GO:0070273	phosphatidylinositol-4-phosphate binding	4/3091	31/18639	0.129032258064516	0.77807578714478	0.779864430366117	1
GO:0140457	protein demethylase activity	4/3091	31/18639	0.129032258064516	0.77807578714478	0.779864430366117	1
GO:0033293	monocarboxylic acid binding	11/3091	79/18639	0.139240506329114	0.839632415874589	0.78100156815647	1
GO:0030159	signaling receptor complex adaptor activity	7/3091	52/18639	0.134615384615385	0.811742527934699	0.781416859756275	1
GO:0004879	nuclear receptor activity	8/3091	59/18639	0.135593220338983	0.817638962762312	0.784248644625076	1
GO:0015149	hexose transmembrane transporter activity	3/3091	24/18639	0.125	0.753760918796506	0.785282605830993	1
GO:0015295	solute:proton symporter activity	3/3091	24/18639	0.125	0.753760918796506	0.785282605830993	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	3/3091	24/18639	0.125	0.753760918796506	0.785282605830993	1
GO:0043998	histone H2A acetyltransferase activity	3/3091	24/18639	0.125	0.753760918796506	0.785282605830993	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	3/3091	24/18639	0.125	0.753760918796506	0.785282605830993	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	3/3091	24/18639	0.125	0.753760918796506	0.785282605830993	1
GO:0055056	D-glucose transmembrane transporter activity	3/3091	24/18639	0.125	0.753760918796506	0.785282605830993	1
GO:0005544	calcium-dependent phospholipid binding	7/3091	53/18639	0.132075471698113	0.796426631181214	0.798178498382203	1
GO:0017046	peptide hormone binding	7/3091	53/18639	0.132075471698113	0.796426631181214	0.798178498382203	1
GO:0008081	phosphoric diester hydrolase activity	12/3091	87/18639	0.137931034482759	0.831736186258213	0.798695285614683	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/3091	17/18639	0.117647058823529	0.709422041220241	0.799350491144408	1
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/3091	17/18639	0.117647058823529	0.709422041220241	0.799350491144408	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/3091	17/18639	0.117647058823529	0.709422041220241	0.799350491144408	1
GO:0019198	transmembrane receptor protein phosphatase activity	2/3091	17/18639	0.117647058823529	0.709422041220241	0.799350491144408	1
GO:0030548	acetylcholine receptor regulator activity	2/3091	17/18639	0.117647058823529	0.709422041220241	0.799350491144408	1
GO:0046965	nuclear retinoid X receptor binding	2/3091	17/18639	0.117647058823529	0.709422041220241	0.799350491144408	1
GO:0048038	quinone binding	2/3091	17/18639	0.117647058823529	0.709422041220241	0.799350491144408	1
GO:0051787	misfolded protein binding	2/3091	17/18639	0.117647058823529	0.709422041220241	0.799350491144408	1
GO:0070403	NAD+ binding	2/3091	17/18639	0.117647058823529	0.709422041220241	0.799350491144408	1
GO:1901567	fatty acid derivative binding	2/3091	17/18639	0.117647058823529	0.709422041220241	0.799350491144408	1
GO:0098531	ligand-modulated transcription factor activity	8/3091	60/18639	0.133333333333333	0.804011646716273	0.799942319610206	1
GO:0015106	bicarbonate transmembrane transporter activity	4/3091	32/18639	0.125	0.753760918796506	0.801079504989421	1
GO:0022884	macromolecule transmembrane transporter activity	4/3091	32/18639	0.125	0.753760918796506	0.801079504989421	1
GO:0042910	xenobiotic transmembrane transporter activity	4/3091	32/18639	0.125	0.753760918796506	0.801079504989421	1
GO:0008139	nuclear localization sequence binding	3/3091	25/18639	0.12	0.723610482044646	0.808595529628816	1
GO:0019706	protein-cysteine S-palmitoyltransferase activity	3/3091	25/18639	0.12	0.723610482044646	0.808595529628816	1
GO:0019707	protein-cysteine S-acyltransferase activity	3/3091	25/18639	0.12	0.723610482044646	0.808595529628816	1
GO:0042974	nuclear retinoic acid receptor binding	3/3091	25/18639	0.12	0.723610482044646	0.808595529628816	1
GO:0004197	cysteine-type endopeptidase activity	12/3091	88/18639	0.136363636363636	0.822284638687097	0.811250221759881	1
GO:0004676	3-phosphoinositide-dependent protein kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:0004711	ribosomal protein S6 kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:0035175	histone H3S10 kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:0035979	histone H2AXS139 kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:0044022	histone H3S28 kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:0044023	histone H4S1 kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:0044024	histone H2AS1 kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:0044025	histone H2BS14 kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:0072354	histone H3T3 kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:0072371	histone H2AS121 kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:0072518	Rho-dependent protein serine/threonine kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:0140823	histone H2BS36 kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:0140855	histone H3S57 kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:0140995	histone H2A kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:0140997	histone H4 kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:0140998	histone H2B kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:1990244	histone H2AT120 kinase activity	36/3091	245/18639	0.146938775510204	0.88605365148324	0.811425200064652	1
GO:0101005	deubiquitinase activity	16/3091	115/18639	0.139130434782609	0.838968674834372	0.814116598248184	1
GO:0001784	phosphotyrosine residue binding	6/3091	47/18639	0.127659574468085	0.769798385153878	0.814188588843968	1
GO:0015171	amino acid transmembrane transporter activity	14/3091	102/18639	0.137254901960784	0.827659048090281	0.817865088696577	1
GO:0004677	DNA-dependent protein kinase activity	36/3091	246/18639	0.146341463414634	0.882451807371519	0.818846024378655	1
GO:0140857	histone H3T45 kinase activity	36/3091	246/18639	0.146341463414634	0.882451807371519	0.818846024378655	1
GO:0019239	deaminase activity	4/3091	33/18639	0.121212121212121	0.730919678832976	0.820605442875085	1
GO:0035591	signaling adaptor activity	18/3091	129/18639	0.13953488372093	0.841407537261216	0.821590244954872	1
GO:0008308	voltage-gated monoatomic anion channel activity	2/3091	18/18639	0.111111111111111	0.670009705596894	0.825048827949119	1
GO:0017075	syntaxin-1 binding	2/3091	18/18639	0.111111111111111	0.670009705596894	0.825048827949119	1
GO:0099602	neurotransmitter receptor regulator activity	2/3091	18/18639	0.111111111111111	0.670009705596894	0.825048827949119	1
GO:0004896	cytokine receptor activity	13/3091	96/18639	0.135416666666667	0.816574328696215	0.825947460348169	1
GO:0035402	histone H3T11 kinase activity	36/3091	247/18639	0.145748987854251	0.878879127989448	0.826060769020261	1
GO:0015179	L-amino acid transmembrane transporter activity	8/3091	62/18639	0.129032258064516	0.77807578714478	0.828721887619073	1
GO:0015145	monosaccharide transmembrane transporter activity	3/3091	26/18639	0.115384615384615	0.695779309658313	0.829731821088086	1
GO:0015216	purine nucleotide transmembrane transporter activity	3/3091	26/18639	0.115384615384615	0.695779309658313	0.829731821088086	1
GO:0120014	phospholipid transfer activity	3/3091	26/18639	0.115384615384615	0.695779309658313	0.829731821088086	1
GO:0004674	protein serine/threonine kinase activity	65/3091	433/18639	0.150115473441109	0.90520941749234	0.830015835773806	1
GO:0004812	aminoacyl-tRNA ligase activity	5/3091	41/18639	0.121951219512195	0.735376506142933	0.83283926113064	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	5/3091	41/18639	0.121951219512195	0.735376506142933	0.83283926113064	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	5/3091	41/18639	0.121951219512195	0.735376506142933	0.83283926113064	1
GO:0140318	protein transporter activity	5/3091	41/18639	0.121951219512195	0.735376506142933	0.83283926113064	1
GO:0140828	metal cation:monoatomic cation antiporter activity	5/3091	41/18639	0.121951219512195	0.735376506142933	0.83283926113064	1
GO:0004679	AMP-activated protein kinase activity	36/3091	248/18639	0.145161290322581	0.875335260537878	0.833070373541292	1
GO:0001216	DNA-binding transcription activator activity	74/3091	491/18639	0.15071283095723	0.908811535493954	0.834991625329476	1
GO:0004090	carbonyl reductase (NADPH) activity	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0005131	growth hormone receptor binding	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0005381	iron ion transmembrane transporter activity	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0008140	cAMP response element binding protein binding	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0015203	polyamine transmembrane transporter activity	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0019531	oxalate transmembrane transporter activity	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0031419	cobalamin binding	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0031996	thioesterase binding	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0032052	bile acid binding	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0035256	G protein-coupled glutamate receptor binding	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0042166	acetylcholine binding	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0042975	peroxisome proliferator activated receptor binding	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0043121	neurotrophin binding	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0043208	glycosphingolipid binding	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0045322	unmethylated CpG binding	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0051378	serotonin binding	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0051864	histone H3K36 demethylase activity	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0070513	death domain binding	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0071723	lipopeptide binding	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0140135	mechanosensitive monoatomic cation channel activity	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:1905394	retromer complex binding	1/3091	10/18639	0.1	0.603008735037205	0.836953789326182	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	4/3091	34/18639	0.117647058823529	0.709422041220241	0.838520380693659	1
GO:0051427	hormone receptor binding	4/3091	34/18639	0.117647058823529	0.709422041220241	0.838520380693659	1
GO:0016782	transferase activity, transferring sulphur-containing groups	9/3091	70/18639	0.128571428571429	0.775296945047835	0.841973484431168	1
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	35/3091	243/18639	0.1440329218107	0.868531099847826	0.843124350245951	1
GO:0008514	organic anion transmembrane transporter activity	39/3091	269/18639	0.144981412639405	0.874250582395947	0.843673584638521	1
GO:0042626	ATPase-coupled transmembrane transporter activity	13/3091	98/18639	0.13265306122449	0.799909546477925	0.847188645773001	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/3091	19/18639	0.105263157894737	0.634746036881268	0.847745019189604	1
GO:0008381	mechanosensitive monoatomic ion channel activity	2/3091	19/18639	0.105263157894737	0.634746036881268	0.847745019189604	1
GO:0034987	immunoglobulin receptor binding	2/3091	19/18639	0.105263157894737	0.634746036881268	0.847745019189604	1
GO:0046624	sphingolipid transporter activity	2/3091	19/18639	0.105263157894737	0.634746036881268	0.847745019189604	1
GO:0140036	ubiquitin-modified protein reader activity	2/3091	19/18639	0.105263157894737	0.634746036881268	0.847745019189604	1
GO:0016405	CoA-ligase activity	3/3091	27/18639	0.111111111111111	0.670009705596894	0.848830623107136	1
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	3/3091	27/18639	0.111111111111111	0.670009705596894	0.848830623107136	1
GO:0008375	acetylglucosaminyltransferase activity	5/3091	43/18639	0.116279069767442	0.70117294771768	0.862621526002813	1
GO:0008234	cysteine-type peptidase activity	26/3091	187/18639	0.13903743315508	0.838407866896648	0.86306088384469	1
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/3091	11/18639	0.0909090909090909	0.548189759124732	0.864007084575137	1
GO:0000099	sulfur amino acid transmembrane transporter activity	1/3091	11/18639	0.0909090909090909	0.548189759124732	0.864007084575137	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/3091	11/18639	0.0909090909090909	0.548189759124732	0.864007084575137	1
GO:0005114	type II transforming growth factor beta receptor binding	1/3091	11/18639	0.0909090909090909	0.548189759124732	0.864007084575137	1
GO:0008172	S-methyltransferase activity	1/3091	11/18639	0.0909090909090909	0.548189759124732	0.864007084575137	1
GO:0008503	benzodiazepine receptor activity	1/3091	11/18639	0.0909090909090909	0.548189759124732	0.864007084575137	1
GO:0015173	aromatic amino acid transmembrane transporter activity	1/3091	11/18639	0.0909090909090909	0.548189759124732	0.864007084575137	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/3091	11/18639	0.0909090909090909	0.548189759124732	0.864007084575137	1
GO:0019107	myristoyltransferase activity	1/3091	11/18639	0.0909090909090909	0.548189759124732	0.864007084575137	1
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/3091	11/18639	0.0909090909090909	0.548189759124732	0.864007084575137	1
GO:0035252	UDP-xylosyltransferase activity	1/3091	11/18639	0.0909090909090909	0.548189759124732	0.864007084575137	1
GO:0042285	xylosyltransferase activity	1/3091	11/18639	0.0909090909090909	0.548189759124732	0.864007084575137	1
GO:0042608	T cell receptor binding	1/3091	11/18639	0.0909090909090909	0.548189759124732	0.864007084575137	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/3091	11/18639	0.0909090909090909	0.548189759124732	0.864007084575137	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/3091	11/18639	0.0909090909090909	0.548189759124732	0.864007084575137	1
GO:0140537	transcription regulator activator activity	1/3091	11/18639	0.0909090909090909	0.548189759124732	0.864007084575137	1
GO:0051019	mitogen-activated protein kinase binding	3/3091	28/18639	0.107142857142857	0.646080787539862	0.866035060392073	1
GO:0051119	sugar transmembrane transporter activity	3/3091	28/18639	0.107142857142857	0.646080787539862	0.866035060392073	1
GO:0051959	dynein light intermediate chain binding	3/3091	28/18639	0.107142857142857	0.646080787539862	0.866035060392073	1
GO:0141052	histone H3 demethylase activity	3/3091	28/18639	0.107142857142857	0.646080787539862	0.866035060392073	1
GO:0001972	retinoic acid binding	2/3091	20/18639	0.1	0.603008735037205	0.867727703212051	1
GO:0005326	neurotransmitter transmembrane transporter activity	2/3091	20/18639	0.1	0.603008735037205	0.867727703212051	1
GO:0016505	peptidase activator activity involved in apoptotic process	2/3091	20/18639	0.1	0.603008735037205	0.867727703212051	1
GO:0030627	pre-mRNA 5'-splice site binding	2/3091	20/18639	0.1	0.603008735037205	0.867727703212051	1
GO:0030742	GTP-dependent protein binding	2/3091	20/18639	0.1	0.603008735037205	0.867727703212051	1
GO:0042288	MHC class I protein binding	2/3091	20/18639	0.1	0.603008735037205	0.867727703212051	1
GO:0004033	aldo-keto reductase (NADPH) activity	4/3091	36/18639	0.111111111111111	0.670009705596894	0.869859439815728	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	4/3091	36/18639	0.111111111111111	0.670009705596894	0.869859439815728	1
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	38/3091	268/18639	0.141791044776119	0.855012385500514	0.87604330948536	1
GO:0004843	cysteine-type deubiquitinase activity	14/3091	108/18639	0.12962962962963	0.781677989863043	0.876097463356793	1
GO:0030414	peptidase inhibitor activity	23/3091	169/18639	0.136094674556213	0.820662775494421	0.876361043104181	1
GO:0008235	metalloexopeptidase activity	8/3091	66/18639	0.121212121212121	0.730919678832976	0.876478085508103	1
GO:0070888	E-box binding	7/3091	59/18639	0.11864406779661	0.715434092417023	0.878797438796193	1
GO:0005416	amino acid:monoatomic cation symporter activity	3/3091	29/18639	0.103448275862069	0.62380213969366	0.88148871153981	1
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	3/3091	29/18639	0.103448275862069	0.62380213969366	0.88148871153981	1
GO:0019213	deacetylase activity	4/3091	37/18639	0.108108108108108	0.651901335175357	0.883462713714215	1
GO:0030280	structural constituent of skin epidermis	4/3091	37/18639	0.108108108108108	0.651901335175357	0.883462713714215	1
GO:0005085	guanyl-nucleotide exchange factor activity	32/3091	230/18639	0.139130434782609	0.838968674834372	0.883774338907573	1
GO:0015101	organic cation transmembrane transporter activity	10/3091	81/18639	0.123456790123457	0.744455228440993	0.883789542210546	1
GO:0001846	opsonin binding	2/3091	21/18639	0.0952380952380952	0.574294033368766	0.885272377886117	1
GO:0005123	death receptor binding	2/3091	21/18639	0.0952380952380952	0.574294033368766	0.885272377886117	1
GO:0008373	sialyltransferase activity	2/3091	21/18639	0.0952380952380952	0.574294033368766	0.885272377886117	1
GO:0035613	RNA stem-loop binding	2/3091	21/18639	0.0952380952380952	0.574294033368766	0.885272377886117	1
GO:0036122	BMP binding	2/3091	21/18639	0.0952380952380952	0.574294033368766	0.885272377886117	1
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	8/3091	67/18639	0.119402985074627	0.72001042989517	0.886535428456944	1
GO:0000340	RNA 7-methylguanosine cap binding	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0003720	telomerase activity	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0004300	enoyl-CoA hydratase activity	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0004875	complement receptor activity	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0005025	transforming growth factor beta receptor activity, type I	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0005026	transforming growth factor beta receptor activity, type II	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0005078	MAP-kinase scaffold activity	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0005165	neurotrophin receptor binding	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0015166	polyol transmembrane transporter activity	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0016208	AMP binding	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0016273	arginine N-methyltransferase activity	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0016274	protein-arginine N-methyltransferase activity	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0016361	activin receptor activity, type I	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0016362	activin receptor activity, type II	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0017002	activin receptor activity	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0034452	dynactin binding	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0035197	siRNA binding	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0035259	nuclear glucocorticoid receptor binding	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0042301	phosphate ion binding	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0097677	STAT family protein binding	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0140900	chloride:bicarbonate antiporter activity	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:1990459	transferrin receptor binding	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:1990817	poly(A) RNA polymerase activity	1/3091	12/18639	0.0833333333333333	0.502507279197671	0.886572797565165	1
GO:0008009	chemokine activity	5/3091	45/18639	0.111111111111111	0.670009705596894	0.887810986181292	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	71/3091	484/18639	0.146694214876033	0.884578929496726	0.887972561356804	1
GO:0031624	ubiquitin conjugating enzyme binding	3/3091	30/18639	0.1	0.603008735037205	0.895332872624731	1
GO:0032452	histone demethylase activity	3/3091	30/18639	0.1	0.603008735037205	0.895332872624731	1
GO:0019905	syntaxin binding	7/3091	61/18639	0.114754098360656	0.69197723692794	0.898863409941738	1
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	2/3091	22/18639	0.0909090909090909	0.548189759124732	0.900637820772799	1
GO:0016881	acid-amino acid ligase activity	2/3091	22/18639	0.0909090909090909	0.548189759124732	0.900637820772799	1
GO:0046972	histone H4K16 acetyltransferase activity	2/3091	22/18639	0.0909090909090909	0.548189759124732	0.900637820772799	1
GO:0061133	endopeptidase activator activity	2/3091	22/18639	0.0909090909090909	0.548189759124732	0.900637820772799	1
GO:0140035	ubiquitin-like protein reader activity	2/3091	22/18639	0.0909090909090909	0.548189759124732	0.900637820772799	1
GO:0001540	amyloid-beta binding	10/3091	83/18639	0.120481927710843	0.726516548237596	0.900775802251299	1
GO:0099106	ion channel regulator activity	21/3091	160/18639	0.13125	0.791448964736331	0.904286058879375	1
GO:0004465	lipoprotein lipase activity	1/3091	13/18639	0.0769230769230769	0.463852873105542	0.905395124441532	1
GO:0008035	high-density lipoprotein particle binding	1/3091	13/18639	0.0769230769230769	0.463852873105542	0.905395124441532	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/3091	13/18639	0.0769230769230769	0.463852873105542	0.905395124441532	1
GO:0031432	titin binding	1/3091	13/18639	0.0769230769230769	0.463852873105542	0.905395124441532	1
GO:0032396	inhibitory MHC class I receptor activity	1/3091	13/18639	0.0769230769230769	0.463852873105542	0.905395124441532	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/3091	13/18639	0.0769230769230769	0.463852873105542	0.905395124441532	1
GO:0051011	microtubule minus-end binding	1/3091	13/18639	0.0769230769230769	0.463852873105542	0.905395124441532	1
GO:1901338	catecholamine binding	1/3091	13/18639	0.0769230769230769	0.463852873105542	0.905395124441532	1
GO:0016878	acid-thiol ligase activity	3/3091	31/18639	0.0967741935483871	0.583556840358585	0.907704491438154	1
GO:0047499	calcium-independent phospholipase A2 activity	3/3091	31/18639	0.0967741935483871	0.583556840358585	0.907704491438154	1
GO:0140359	ABC-type transporter activity	5/3091	47/18639	0.106382978723404	0.641498654294899	0.908921842612224	1
GO:0004866	endopeptidase inhibitor activity	21/3091	161/18639	0.130434782608696	0.786533132657224	0.909851475021989	1
GO:0016247	channel regulator activity	22/3091	168/18639	0.130952380952381	0.789654295882054	0.91080457670352	1
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	2/3091	23/18639	0.0869565217391304	0.524355421771482	0.914064057257058	1
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	2/3091	23/18639	0.0869565217391304	0.524355421771482	0.914064057257058	1
GO:0015144	carbohydrate transmembrane transporter activity	4/3091	40/18639	0.1	0.603008735037205	0.917092109520155	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	3/3091	32/18639	0.09375	0.56532068909738	0.918734662450091	1
GO:0047498	calcium-dependent phospholipase A2 activity	3/3091	32/18639	0.09375	0.56532068909738	0.918734662450091	1
GO:0170055	lipid transmembrane transporter activity	6/3091	56/18639	0.107142857142857	0.646080787539862	0.920508871055659	1
GO:0141108	transporter regulator activity	22/3091	170/18639	0.129411764705882	0.780364245342265	0.920867566498865	1
GO:0005313	L-glutamate transmembrane transporter activity	1/3091	14/18639	0.0714285714285714	0.430720525026575	0.92109488125197	1
GO:0005545	1-phosphatidylinositol binding	1/3091	14/18639	0.0714285714285714	0.430720525026575	0.92109488125197	1
GO:0008392	arachidonate epoxygenase activity	1/3091	14/18639	0.0714285714285714	0.430720525026575	0.92109488125197	1
GO:0008494	translation activator activity	1/3091	14/18639	0.0714285714285714	0.430720525026575	0.92109488125197	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/3091	14/18639	0.0714285714285714	0.430720525026575	0.92109488125197	1
GO:0031404	chloride ion binding	1/3091	14/18639	0.0714285714285714	0.430720525026575	0.92109488125197	1
GO:0043176	amine binding	1/3091	14/18639	0.0714285714285714	0.430720525026575	0.92109488125197	1
GO:0098821	BMP receptor activity	1/3091	14/18639	0.0714285714285714	0.430720525026575	0.92109488125197	1
GO:0001217	DNA-binding transcription repressor activity	38/3091	278/18639	0.136690647482014	0.82425654429546	0.921703075178338	1
GO:0015370	solute:sodium symporter activity	9/3091	79/18639	0.113924050632911	0.686971976624664	0.92439892616368	1
GO:0005315	phosphate transmembrane transporter activity	2/3091	24/18639	0.0833333333333333	0.502507279197671	0.925771461932155	1
GO:0030552	cAMP binding	2/3091	24/18639	0.0833333333333333	0.502507279197671	0.925771461932155	1
GO:0035035	histone acetyltransferase binding	2/3091	24/18639	0.0833333333333333	0.502507279197671	0.925771461932155	1
GO:0035254	glutamate receptor binding	5/3091	49/18639	0.102040816326531	0.61531503575225	0.926467559192087	1
GO:0042562	hormone binding	11/3091	94/18639	0.117021276595745	0.705648519724389	0.926913682443484	1
GO:0140311	protein sequestering activity	3/3091	33/18639	0.0909090909090909	0.548189759124732	0.928547584407592	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	16/3091	130/18639	0.123076923076923	0.742164596968867	0.928797113916197	1
GO:0015294	solute:monoatomic cation symporter activity	14/3091	116/18639	0.120689655172414	0.727769162975937	0.929558116475288	1
GO:0004620	phospholipase activity	13/3091	109/18639	0.119266055045872	0.719184729860886	0.930279185121389	1
GO:0048020	CCR chemokine receptor binding	5/3091	50/18639	0.1	0.603008735037205	0.934058282980301	1
GO:0004559	alpha-mannosidase activity	1/3091	15/18639	0.0666666666666667	0.402005823358137	0.934189953576811	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/3091	15/18639	0.0666666666666667	0.402005823358137	0.934189953576811	1
GO:0008020	G protein-coupled photoreceptor activity	1/3091	15/18639	0.0666666666666667	0.402005823358137	0.934189953576811	1
GO:0010181	FMN binding	1/3091	15/18639	0.0666666666666667	0.402005823358137	0.934189953576811	1
GO:0015250	water channel activity	1/3091	15/18639	0.0666666666666667	0.402005823358137	0.934189953576811	1
GO:0034483	heparan sulfate sulfotransferase activity	1/3091	15/18639	0.0666666666666667	0.402005823358137	0.934189953576811	1
GO:0001848	complement binding	2/3091	25/18639	0.08	0.482406988029764	0.935960673436793	1
GO:0004709	MAP kinase kinase kinase activity	2/3091	25/18639	0.08	0.482406988029764	0.935960673436793	1
GO:0015645	fatty acid ligase activity	2/3091	25/18639	0.08	0.482406988029764	0.935960673436793	1
GO:0120515	fatty acid-CoA ligase activity	2/3091	25/18639	0.08	0.482406988029764	0.935960673436793	1
GO:0070851	growth factor receptor binding	17/3091	139/18639	0.122302158273381	0.737492697527517	0.937897539728202	1
GO:0046943	carboxylic acid transmembrane transporter activity	24/3091	188/18639	0.127659574468085	0.769798385153878	0.938893300900166	1
GO:0015459	potassium channel regulator activity	6/3091	59/18639	0.101694915254237	0.613229222071734	0.94152271815358	1
GO:0005342	organic acid transmembrane transporter activity	24/3091	189/18639	0.126984126984127	0.765725377825022	0.942523079871033	1
GO:0005112	Notch binding	2/3091	26/18639	0.0769230769230769	0.463852873105542	0.944813077799185	1
GO:0008157	protein phosphatase 1 binding	2/3091	26/18639	0.0769230769230769	0.463852873105542	0.944813077799185	1
GO:0030247	polysaccharide binding	2/3091	26/18639	0.0769230769230769	0.463852873105542	0.944813077799185	1
GO:0051139	metal cation:proton antiporter activity	2/3091	26/18639	0.0769230769230769	0.463852873105542	0.944813077799185	1
GO:0052742	phosphatidylinositol kinase activity	2/3091	26/18639	0.0769230769230769	0.463852873105542	0.944813077799185	1
GO:0070412	R-SMAD binding	2/3091	26/18639	0.0769230769230769	0.463852873105542	0.944813077799185	1
GO:0004623	phospholipase A2 activity	3/3091	35/18639	0.0857142857142857	0.51686463003189	0.944980304120271	1
GO:0016229	steroid dehydrogenase activity	3/3091	35/18639	0.0857142857142857	0.51686463003189	0.944980304120271	1
GO:0005149	interleukin-1 receptor binding	1/3091	16/18639	0.0625	0.376880459398253	0.945112357651879	1
GO:0005521	lamin binding	1/3091	16/18639	0.0625	0.376880459398253	0.945112357651879	1
GO:0008391	arachidonate monooxygenase activity	1/3091	16/18639	0.0625	0.376880459398253	0.945112357651879	1
GO:0015385	sodium:proton antiporter activity	1/3091	16/18639	0.0625	0.376880459398253	0.945112357651879	1
GO:0015923	mannosidase activity	1/3091	16/18639	0.0625	0.376880459398253	0.945112357651879	1
GO:0022841	potassium ion leak channel activity	1/3091	16/18639	0.0625	0.376880459398253	0.945112357651879	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/3091	16/18639	0.0625	0.376880459398253	0.945112357651879	1
GO:0140327	flippase activity	1/3091	16/18639	0.0625	0.376880459398253	0.945112357651879	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	5/3091	52/18639	0.0961538461538462	0.579816091381928	0.947166390446097	1
GO:0005548	phospholipid transporter activity	7/3091	68/18639	0.102941176470588	0.620744286067711	0.948338045618036	1
GO:0061135	endopeptidase regulator activity	23/3091	184/18639	0.125	0.753760918796506	0.949078060223377	1
GO:0000149	SNARE binding	12/3091	106/18639	0.113207547169811	0.682651398155326	0.950236955885299	1
GO:0004190	aspartic-type endopeptidase activity	3/3091	36/18639	0.0833333333333333	0.502507279197671	0.951809473602502	1
GO:0045505	dynein intermediate chain binding	3/3091	36/18639	0.0833333333333333	0.502507279197671	0.951809473602502	1
GO:0001671	ATPase activator activity	2/3091	27/18639	0.0740740740740741	0.446673137064596	0.952491674174549	1
GO:0023026	MHC class II protein complex binding	2/3091	27/18639	0.0740740740740741	0.446673137064596	0.952491674174549	1
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	2/3091	27/18639	0.0740740740740741	0.446673137064596	0.952491674174549	1
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/3091	17/18639	0.0588235294117647	0.35471102061012	0.954222474308597	1
GO:0008429	phosphatidylethanolamine binding	1/3091	17/18639	0.0588235294117647	0.35471102061012	0.954222474308597	1
GO:0009881	photoreceptor activity	1/3091	17/18639	0.0588235294117647	0.35471102061012	0.954222474308597	1
GO:0015278	intracellularly gated calcium channel activity	1/3091	17/18639	0.0588235294117647	0.35471102061012	0.954222474308597	1
GO:0016805	dipeptidase activity	1/3091	17/18639	0.0588235294117647	0.35471102061012	0.954222474308597	1
GO:0045125	bioactive lipid receptor activity	1/3091	17/18639	0.0588235294117647	0.35471102061012	0.954222474308597	1
GO:0140303	intramembrane lipid transporter activity	4/3091	45/18639	0.0888888888888889	0.536007764477515	0.95426541641082	1
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	14/3091	122/18639	0.114754098360656	0.69197723692794	0.955474150969303	1
GO:0030551	cyclic nucleotide binding	3/3091	37/18639	0.0810810810810811	0.488926001381517	0.957840070063233	1
GO:0070001	aspartic-type peptidase activity	3/3091	37/18639	0.0810810810810811	0.488926001381517	0.957840070063233	1
GO:0004970	glutamate-gated receptor activity	1/3091	18/18639	0.0555555555555556	0.335004852798447	0.961820924094448	1
GO:0005372	water transmembrane transporter activity	1/3091	18/18639	0.0555555555555556	0.335004852798447	0.961820924094448	1
GO:0015172	acidic amino acid transmembrane transporter activity	1/3091	18/18639	0.0555555555555556	0.335004852798447	0.961820924094448	1
GO:0017128	phospholipid scramblase activity	1/3091	18/18639	0.0555555555555556	0.335004852798447	0.961820924094448	1
GO:0022851	GABA-gated chloride ion channel activity	1/3091	18/18639	0.0555555555555556	0.335004852798447	0.961820924094448	1
GO:0032393	MHC class I receptor activity	1/3091	18/18639	0.0555555555555556	0.335004852798447	0.961820924094448	1
GO:0050811	GABA receptor binding	1/3091	18/18639	0.0555555555555556	0.335004852798447	0.961820924094448	1
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/3091	18/18639	0.0555555555555556	0.335004852798447	0.961820924094448	1
GO:0015293	symporter activity	17/3091	146/18639	0.116438356164384	0.702133458604964	0.962573651156685	1
GO:0004181	metallocarboxypeptidase activity	2/3091	29/18639	0.0689655172413793	0.415868093129107	0.964894291918695	1
GO:0099604	ligand-gated calcium channel activity	2/3091	29/18639	0.0689655172413793	0.415868093129107	0.964894291918695	1
GO:0015291	secondary active transmembrane transporter activity	37/3091	287/18639	0.128919860627178	0.777398020779672	0.965397021576894	1
GO:0042379	chemokine receptor binding	7/3091	72/18639	0.0972222222222222	0.586258492397282	0.96564363438906	1
GO:0008083	growth factor activity	19/3091	162/18639	0.117283950617284	0.707232467018944	0.966752408678033	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/3091	19/18639	0.0526315789473684	0.317373018440634	0.968158474366939	1
GO:0004890	GABA-A receptor activity	1/3091	19/18639	0.0526315789473684	0.317373018440634	0.968158474366939	1
GO:0022840	leak channel activity	1/3091	19/18639	0.0526315789473684	0.317373018440634	0.968158474366939	1
GO:0022842	narrow pore channel activity	1/3091	19/18639	0.0526315789473684	0.317373018440634	0.968158474366939	1
GO:0031420	alkali metal ion binding	1/3091	19/18639	0.0526315789473684	0.317373018440634	0.968158474366939	1
GO:0008188	neuropeptide receptor activity	4/3091	48/18639	0.0833333333333333	0.502507279197671	0.968447554200981	1
GO:0001664	G protein-coupled receptor binding	38/3091	297/18639	0.127946127946128	0.77152632765703	0.970984638567781	1
GO:0042277	peptide binding	31/3091	249/18639	0.124497991967871	0.750733766512183	0.971543295882397	1
GO:0071855	neuropeptide receptor binding	3/3091	40/18639	0.075	0.452256551277904	0.971952028550985	1
GO:0001614	purinergic nucleotide receptor activity	1/3091	20/18639	0.05	0.301504367518602	0.973444304427723	1
GO:0016502	nucleotide receptor activity	1/3091	20/18639	0.05	0.301504367518602	0.973444304427723	1
GO:0061980	regulatory RNA binding	5/3091	58/18639	0.0862068965517241	0.519835116411383	0.973551284680685	1
GO:0008236	serine-type peptidase activity	23/3091	194/18639	0.118556701030928	0.714907263188439	0.973843923085472	1
GO:0005164	tumor necrosis factor receptor binding	2/3091	31/18639	0.0645161290322581	0.38903789357239	0.974149755986596	1
GO:0005184	neuropeptide hormone activity	2/3091	31/18639	0.0645161290322581	0.38903789357239	0.974149755986596	1
GO:0032813	tumor necrosis factor receptor superfamily binding	4/3091	50/18639	0.08	0.482406988029764	0.975493963776585	1
GO:0008227	G protein-coupled amine receptor activity	3/3091	41/18639	0.0731707317073171	0.44122590368576	0.975563989313252	1
GO:0016298	lipase activity	14/3091	130/18639	0.107692307692308	0.649394022347759	0.976856764779874	1
GO:0008194	UDP-glycosyltransferase activity	16/3091	145/18639	0.110344827586207	0.665388949006571	0.97707503596906	1
GO:0120015	sterol transfer activity	2/3091	32/18639	0.0625	0.376880459398253	0.977844095555697	1
GO:0160041	neuropeptide activity	2/3091	32/18639	0.0625	0.376880459398253	0.977844095555697	1
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	1/3091	21/18639	0.0476190476190476	0.287147016684383	0.977852900754803	1
GO:0019894	kinesin binding	3/3091	42/18639	0.0714285714285714	0.430720525026575	0.978730695918502	1
GO:0035198	miRNA binding	3/3091	42/18639	0.0714285714285714	0.430720525026575	0.978730695918502	1
GO:0140767	enzyme-substrate adaptor activity	15/3091	139/18639	0.107913669064748	0.650728850759573	0.979627098866181	1
GO:0004252	serine-type endopeptidase activity	20/3091	176/18639	0.113636363636364	0.685237198905914	0.979852423467738	1
GO:0017171	serine hydrolase activity	23/3091	198/18639	0.116161616161616	0.700464692214935	0.980271522399114	1
GO:0008970	phospholipase A1 activity	1/3091	22/18639	0.0454545454545455	0.274094879562366	0.981529809325375	1
GO:0050321	tau-protein kinase activity	1/3091	22/18639	0.0454545454545455	0.274094879562366	0.981529809325375	1
GO:0140375	immune receptor activity	17/3091	156/18639	0.108974358974359	0.657124903566185	0.982849903107373	1
GO:0015020	glucuronosyltransferase activity	2/3091	34/18639	0.0588235294117647	0.35471102061012	0.983759804453852	1
GO:0052866	phosphatidylinositol phosphate phosphatase activity	2/3091	34/18639	0.0588235294117647	0.35471102061012	0.983759804453852	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/3091	23/18639	0.0434782608695652	0.262177710885741	0.984596434419389	1
GO:0016917	GABA receptor activity	1/3091	23/18639	0.0434782608695652	0.262177710885741	0.984596434419389	1
GO:0042171	lysophosphatidic acid acyltransferase activity	1/3091	23/18639	0.0434782608695652	0.262177710885741	0.984596434419389	1
GO:0071617	lysophospholipid acyltransferase activity	1/3091	23/18639	0.0434782608695652	0.262177710885741	0.984596434419389	1
GO:0004175	endopeptidase activity	52/3091	405/18639	0.128395061728395	0.774233437578633	0.985097825201157	1
GO:0042605	peptide antigen binding	3/3091	45/18639	0.0666666666666667	0.402005823358137	0.986047702666967	1
GO:0004806	triacylglycerol lipase activity	1/3091	24/18639	0.0416666666666667	0.251253639598835	0.987154041918834	1
GO:0003730	mRNA 3'-UTR binding	31/3091	262/18639	0.118320610687023	0.713483617792113	0.987625246955534	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	3/3091	46/18639	0.0652173913043478	0.393266566328612	0.987896821777737	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	2/3091	36/18639	0.0555555555555556	0.335004852798447	0.988127759765979	1
GO:0120013	lipid transfer activity	5/3091	65/18639	0.0769230769230769	0.463852873105542	0.988712954178203	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	4/3091	56/18639	0.0714285714285714	0.430720525026575	0.988771941214811	1
GO:0015271	outward rectifier potassium channel activity	1/3091	25/18639	0.04	0.241203494014882	0.989287098938919	1
GO:0120020	cholesterol transfer activity	1/3091	25/18639	0.04	0.241203494014882	0.989287098938919	1
GO:0023023	MHC protein complex binding	2/3091	37/18639	0.0540540540540541	0.325950667587678	0.989858484891851	1
GO:0005179	hormone activity	13/3091	132/18639	0.0984848484848485	0.593872239051793	0.990197687011665	1
GO:0005319	lipid transporter activity	19/3091	178/18639	0.106741573033708	0.643661009309376	0.990369263064635	1
GO:0008066	glutamate receptor activity	1/3091	26/18639	0.0384615384615385	0.231926436552771	0.991066059784509	1
GO:0019865	immunoglobulin binding	1/3091	26/18639	0.0384615384615385	0.231926436552771	0.991066059784509	1
GO:0016757	glycosyltransferase activity	31/3091	267/18639	0.116104868913858	0.700122501354058	0.991189811394477	1
GO:0005104	fibroblast growth factor receptor binding	1/3091	27/18639	0.037037037037037	0.223336568532298	0.992549690000276	1
GO:0008395	steroid hydroxylase activity	1/3091	27/18639	0.037037037037037	0.223336568532298	0.992549690000276	1
GO:0016758	hexosyltransferase activity	21/3091	197/18639	0.106598984771574	0.642801189633569	0.993060420008568	1
GO:0098960	postsynaptic neurotransmitter receptor activity	5/3091	69/18639	0.072463768115942	0.436962851476235	0.993187188458357	1
GO:0050698	proteoglycan sulfotransferase activity	1/3091	28/18639	0.0357142857142857	0.215360262513287	0.993787005077063	1
GO:0001727	lipid kinase activity	2/3091	41/18639	0.0487804878048781	0.294150602457173	0.994629838922979	1
GO:0042287	MHC protein binding	2/3091	41/18639	0.0487804878048781	0.294150602457173	0.994629838922979	1
GO:0004497	monooxygenase activity	9/3091	106/18639	0.0849056603773585	0.511988548616495	0.994788133817349	1
GO:0008146	sulfotransferase activity	3/3091	53/18639	0.0566037735849057	0.341325699077663	0.995614805847508	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	3/3091	53/18639	0.0566037735849057	0.341325699077663	0.995614805847508	1
GO:0022824	transmitter-gated monoatomic ion channel activity	4/3091	63/18639	0.0634920634920635	0.382862688912511	0.99564338061268	1
GO:0022835	transmitter-gated channel activity	4/3091	63/18639	0.0634920634920635	0.382862688912511	0.99564338061268	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/3091	30/18639	0.0333333333333333	0.201002911679068	0.995679436757601	1
GO:0005245	voltage-gated calcium channel activity	2/3091	43/18639	0.0465116279069767	0.280469179087072	0.996103877816518	1
GO:0016411	acylglycerol O-acyltransferase activity	1/3091	31/18639	0.032258064516129	0.194518946786195	0.996397092783301	1
GO:0008374	O-acyltransferase activity	3/3091	55/18639	0.0545454545454545	0.328913855474839	0.996737648713585	1
GO:0001653	peptide receptor activity	11/3091	128/18639	0.0859375	0.518210631672598	0.997062451102905	1
GO:0015108	chloride transmembrane transporter activity	10/3091	121/18639	0.0826446280991736	0.498354326477029	0.997467628419175	1
GO:0042923	neuropeptide binding	1/3091	33/18639	0.0303030303030303	0.182729919708244	0.997494672219058	1
GO:0004180	carboxypeptidase activity	2/3091	46/18639	0.0434782608695652	0.262177710885741	0.997600221108019	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	11/3091	130/18639	0.0846153846153846	0.510238160416096	0.997626420787855	1
GO:0008528	G protein-coupled peptide receptor activity	10/3091	122/18639	0.0819672131147541	0.494269454948528	0.997731819031408	1
GO:0015103	inorganic anion transmembrane transporter activity	15/3091	165/18639	0.0909090909090909	0.548189759124732	0.998107873794559	1
GO:0008509	monoatomic anion transmembrane transporter activity	13/3091	149/18639	0.087248322147651	0.526115003723736	0.998160644107655	1
GO:0005126	cytokine receptor binding	29/3091	275/18639	0.105454545454545	0.635900120584689	0.998370138097394	1
GO:0005125	cytokine activity	23/3091	234/18639	0.0982905982905983	0.592700893412637	0.998902569877189	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	4/3091	73/18639	0.0547945205479452	0.330415745225866	0.99893266838897	1
GO:0030594	neurotransmitter receptor activity	6/3091	97/18639	0.0618556701030928	0.372995093837446	0.999399024701891	1
GO:0015081	sodium ion transmembrane transporter activity	13/3091	164/18639	0.0792682926829268	0.477994728992906	0.999629141788178	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	5/3091	91/18639	0.0549450549450549	0.331323480789673	0.999646351291255	1
GO:0005253	monoatomic anion channel activity	6/3091	103/18639	0.058252427184466	0.351267224293517	0.999731297168568	1
GO:0005254	chloride channel activity	4/3091	83/18639	0.0481927710843374	0.290606619295038	0.99975135929626	1
GO:0099095	ligand-gated monoatomic anion channel activity	1/3091	47/18639	0.0212765957446809	0.12829973085898	0.999803291176792	1
GO:0015085	calcium ion transmembrane transporter activity	7/3091	147/18639	0.0476190476190476	0.287147016684383	0.999997565397892	1
GO:0005262	calcium channel activity	5/3091	131/18639	0.0381679389312977	0.230156005739391	0.999999021194726	1
GO:0099094	ligand-gated monoatomic cation channel activity	5/3091	136/18639	0.0367647058823529	0.221694387881325	0.999999545555577	1
GO:0005249	voltage-gated potassium channel activity	2/3091	98/18639	0.0204081632653061	0.12306300715045	0.999999624542202	1
GO:0030527	structural constituent of chromatin	2/3091	98/18639	0.0204081632653061	0.12306300715045	0.999999624542202	1
GO:0022843	voltage-gated monoatomic cation channel activity	5/3091	143/18639	0.034965034965035	0.210842215047974	0.999999846141227	1
GO:0005244	voltage-gated monoatomic ion channel activity	7/3091	173/18639	0.0404624277456647	0.243991973714476	0.999999945172028	1
GO:0005267	potassium channel activity	3/3091	124/18639	0.0241935483870968	0.145889210089646	0.99999994741973	1
GO:0022832	voltage-gated channel activity	7/3091	175/18639	0.04	0.241203494014882	0.99999995930101	1
GO:0003823	antigen binding	6/3091	174/18639	0.0344827586206897	0.207934046564553	0.999999991925009	1
GO:0046873	metal ion transmembrane transporter activity	33/3091	450/18639	0.0733333333333333	0.44220640569395	0.999999998578178	1
GO:0015079	potassium ion transmembrane transporter activity	4/3091	160/18639	0.025	0.150752183759301	0.999999998691204	1
GO:0015276	ligand-gated monoatomic ion channel activity	6/3091	186/18639	0.032258064516129	0.194518946786195	0.999999998753654	1
GO:0022834	ligand-gated channel activity	6/3091	188/18639	0.0319148936170213	0.19244959628847	0.999999999089144	1
GO:0022836	gated channel activity	14/3091	318/18639	0.0440251572327044	0.265475543727071	0.999999999997285	1
GO:0045182	translation regulator activity	14/3091	356/18639	0.0393258426966292	0.237138266587665	0.999999999999989	1
GO:0005261	monoatomic cation channel activity	12/3091	341/18639	0.0351906158357771	0.212202487403122	0.999999999999997	1
GO:0005216	monoatomic ion channel activity	20/3091	448/18639	0.0446428571428571	0.269200328141609	1	1
GO:0030371	translation repressor activity	6/3091	329/18639	0.0182370820668693	0.109971197879125	1	1