ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0140097	catalytic activity, acting on DNA	149/2977	336/18639	0.443452380952381	2.77645580402131	2.14076961207033e-35	2.73376279461381e-32
GO:0008094	ATP-dependent activity, acting on DNA	101/2977	210/18639	0.480952380952381	3.01124334181103	7.79145947459607e-28	4.97484687452959e-25
GO:0004386	helicase activity	79/2977	155/18639	0.509677419354839	3.19109083619578	4.02477392794465e-24	1.71321210199511e-21
GO:0016887	ATP hydrolysis activity	147/2977	417/18639	0.352517985611511	2.20711546315517	1.73813309045248e-22	5.54898989126955e-20
GO:0003697	single-stranded DNA binding	65/2977	121/18639	0.537190082644628	3.36334764877838	1.05047743068461e-21	2.6829193579685e-19
GO:0003678	DNA helicase activity	48/2977	74/18639	0.648648648648649	4.06118984284923	3.54719171479868e-21	7.54960636632987e-19
GO:0140098	catalytic activity, acting on RNA	135/2977	387/18639	0.348837209302326	2.18407011897415	2.77978514866071e-20	4.5946382206108e-18
GO:0140104	molecular carrier activity	100/2977	249/18639	0.401606425702811	2.5144582360345	2.87839512645939e-20	4.5946382206108e-18
GO:0003689	DNA clamp loader activity	73/2977	160/18639	0.45625	2.85658170977494	7.63226582962732e-19	1.08293371827045e-16
GO:0017116	single-stranded DNA helicase activity	39/2977	58/18639	0.672413793103448	4.20998343622948	2.73504740536659e-18	3.49265553665313e-16
GO:0140713	histone chaperone activity	72/2977	164/18639	0.439024390243902	2.74873214973332	1.81698674006268e-17	2.10935642460004e-15
GO:0140658	ATP-dependent chromatin remodeler activity	69/2977	158/18639	0.436708860759494	2.73423461729802	1.18874891630851e-16	1.26502697177163e-14
GO:0015616	DNA translocase activity	67/2977	152/18639	0.440789473684211	2.75978333893181	1.84224548599154e-16	1.80965191200861e-14
GO:0000510	H3-H4 histone complex chaperone activity	66/2977	151/18639	0.437086092715232	2.73659646695304	5.18086807420275e-16	3.89174619456289e-14
GO:0140584	chromatin extrusion motor activity	66/2977	151/18639	0.437086092715232	2.73659646695304	5.18086807420275e-16	3.89174619456289e-14
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	66/2977	151/18639	0.437086092715232	2.73659646695304	5.18086807420275e-16	3.89174619456289e-14
GO:0140849	ATP-dependent H2AZ histone chaperone activity	66/2977	151/18639	0.437086092715232	2.73659646695304	5.18086807420275e-16	3.89174619456289e-14
GO:0140597	protein carrier chaperone	76/2977	188/18639	0.404255319148936	2.53104296057004	6.38942553256435e-16	4.50301408816e-14
GO:0043021	ribonucleoprotein complex binding	73/2977	177/18639	0.412429378531073	2.58222075459882	6.69986434416915e-16	4.50301408816e-14
GO:0140674	ATP-dependent histone chaperone activity	66/2977	152/18639	0.434210526315789	2.71859254282835	7.74306680469041e-16	4.94394815479483e-14
GO:0042393	histone binding	91/2977	247/18639	0.368421052631579	2.30668458179375	9.2583391159561e-16	5.62995192908378e-14
GO:0061775	cohesin loader activity	66/2977	153/18639	0.431372549019608	2.70082396411705	1.151467563871e-15	6.68374581392395e-14
GO:0008017	microtubule binding	97/2977	276/18639	0.351449275362319	2.20042426720802	3.54017894887848e-15	1.96556892074688e-13
GO:0015631	tubulin binding	122/2977	385/18639	0.316883116883117	1.98400551413652	7.76799004790833e-15	4.0288255980571e-13
GO:0003684	damaged DNA binding	41/2977	74/18639	0.554054054054054	3.46893299076705	7.88728582235142e-15	4.0288255980571e-13
GO:0009378	four-way junction helicase activity	30/2977	48/18639	0.625	3.91312562982869	4.09628587643808e-13	1.86819895150408e-11
GO:0036121	double-stranded DNA helicase activity	30/2977	48/18639	0.625	3.91312562982869	4.09628587643808e-13	1.86819895150408e-11
GO:0043138	3'-5' DNA helicase activity	30/2977	48/18639	0.625	3.91312562982869	4.09628587643808e-13	1.86819895150408e-11
GO:0061749	forked DNA-dependent helicase activity	29/2977	47/18639	0.617021276595745	3.86317083455428	1.62114391393496e-12	6.90066926031647e-11
GO:1990518	single-stranded 3'-5' DNA helicase activity	29/2977	47/18639	0.617021276595745	3.86317083455428	1.62114391393496e-12	6.90066926031647e-11
GO:0000287	magnesium ion binding	76/2977	230/18639	0.330434782608696	2.06885250690073	1.0246438307824e-10	4.10153822221272e-09
GO:0004518	nuclease activity	71/2977	209/18639	0.339712918660287	2.12694292606956	1.02779344644328e-10	4.10153822221272e-09
GO:0031491	nucleosome binding	35/2977	74/18639	0.472972972972973	2.9612842604109	2.62259451787624e-10	1.01486460585696e-08
GO:0140297	DNA-binding transcription factor binding	131/2977	488/18639	0.26844262295082	1.68071953281167	4.06223793699421e-10	1.52572877810047e-08
GO:0004527	exonuclease activity	37/2977	84/18639	0.44047619047619	2.75782187245069	1.01916786965567e-09	3.7185067701437e-08
GO:0016853	isomerase activity	61/2977	180/18639	0.338888888888889	2.12178367484044	2.32168465712658e-09	8.1089586576206e-08
GO:0043022	ribosome binding	44/2977	112/18639	0.392857142857143	2.45967896732089	2.34950250847269e-09	8.1089586576206e-08
GO:0003712	transcription coregulator activity	129/2977	495/18639	0.260606060606061	1.63165480807402	4.12450242797478e-09	1.38604989487468e-07
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	29/2977	60/18639	0.483333333333333	3.02615048706752	4.72786051573557e-09	1.54807125092162e-07
GO:0140101	catalytic activity, acting on a tRNA	50/2977	139/18639	0.359712230215827	2.25215863587263	6.74496059509368e-09	2.15332866998366e-07
GO:0000217	DNA secondary structure binding	22/2977	39/18639	0.564102564102564	3.53184672230692	8.72478630619659e-09	2.71745173488123e-07
GO:0003714	transcription corepressor activity	64/2977	204/18639	0.313725490196078	1.96423561026695	2.89972327879614e-08	8.81653958814923e-07
GO:0008186	ATP-dependent activity, acting on RNA	33/2977	79/18639	0.417721518987342	2.61535485132854	3.96276684002675e-08	1.17684959411957e-06
GO:0016741	transferase activity, transferring one-carbon groups	66/2977	215/18639	0.306976744186047	1.92198170469725	4.53644571532224e-08	1.31660026783329e-06
GO:0000049	tRNA binding	33/2977	80/18639	0.4125	2.58266291568693	5.71637017224076e-08	1.62217882443366e-06
GO:0008408	3'-5' exonuclease activity	26/2977	58/18639	0.448275862068966	2.80665562415299	1.99175166879542e-07	5.52927582837338e-06
GO:0003688	DNA replication origin binding	12/2977	16/18639	0.75	4.69575075579442	2.60987888268305e-07	7.09109645358779e-06
GO:0003724	RNA helicase activity	31/2977	77/18639	0.402597402597403	2.52066274337017	2.75326598781965e-07	7.32483472176186e-06
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	53/2977	167/18639	0.317365269461078	1.98702427191301	2.88858813459951e-07	7.52801438343586e-06
GO:0008168	methyltransferase activity	61/2977	204/18639	0.299019607843137	1.87216206603569	4.00741970497098e-07	1.02349499264959e-05
GO:0004532	RNA exonuclease activity	20/2977	40/18639	0.5	3.13050050386295	5.81454184501938e-07	1.45591567374309e-05
GO:0017056	structural constituent of nuclear pore	15/2977	25/18639	0.6	3.75660060463554	7.12699907797853e-07	1.723792200732e-05
GO:0045296	cadherin binding	88/2977	334/18639	0.263473053892216	1.64960505592778	7.15434507743115e-07	1.723792200732e-05
GO:0140030	modification-dependent protein binding	53/2977	173/18639	0.30635838150289	1.91811013531487	9.92007100883611e-07	2.34591308857106e-05
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	19/2977	38/18639	0.5	3.13050050386295	1.11402651466792e-06	2.55586283583326e-05
GO:0003713	transcription coactivator activity	71/2977	256/18639	0.27734375	1.73644949823648	1.12081690529885e-06	2.55586283583326e-05
GO:0140142	nucleocytoplasmic carrier activity	17/2977	32/18639	0.53125	3.32615678535438	1.37292492876028e-06	3.0758335684682e-05
GO:0008173	RNA methyltransferase activity	27/2977	67/18639	0.402985074626866	2.5230899583373	1.5588116277488e-06	3.43207318730211e-05
GO:0000400	four-way junction DNA binding	12/2977	18/18639	0.666666666666667	4.17400067181727	1.94030460935358e-06	4.1996084510924e-05
GO:0004540	RNA nuclease activity	40/2977	121/18639	0.330578512396694	2.06975239924823	2.56115485876765e-06	5.45099125774382e-05
GO:0008175	tRNA methyltransferase activity	17/2977	34/18639	0.5	3.13050050386295	4.10335669502375e-06	8.59014180253333e-05
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	88/2977	349/18639	0.25214899713467	1.57870512515725	5.02996431462807e-06	0.000103601039190001
GO:0042162	telomeric DNA binding	18/2977	38/18639	0.473684210526316	2.96573731944911	5.72418132668357e-06	0.000116028246891665
GO:0000175	3'-5'-RNA exonuclease activity	17/2977	35/18639	0.485714285714286	3.04105763232401	6.79274839443205e-06	0.000135536557807652
GO:0030515	snoRNA binding	16/2977	32/18639	0.5	3.13050050386295	7.89107533395995e-06	0.000155029280022567
GO:0016423	tRNA (guanine) methyltransferase activity	9/2977	12/18639	0.75	4.69575075579442	9.26689363485565e-06	0.000179300351086525
GO:0043024	ribosomal small subunit binding	12/2977	20/18639	0.6	3.75660060463554	9.60374367286652e-06	0.000182279452587577
GO:0004519	endonuclease activity	40/2977	127/18639	0.31496062992126	1.97196882133099	9.70634516519594e-06	0.000182279452587577
GO:0140463	chromatin-protein adaptor activity	22/2977	54/18639	0.407407407407407	2.55077818833277	1.15489454943099e-05	0.000213739179655561
GO:0031625	ubiquitin protein ligase binding	77/2977	302/18639	0.254966887417219	1.59634793905594	1.25287647463874e-05	0.000228560465444809
GO:0032356	oxidized DNA binding	8/2977	10/18639	0.8	5.00880080618072	1.39347211175954e-05	0.000250628716439004
GO:0044389	ubiquitin-like protein ligase binding	80/2977	322/18639	0.248447204968944	1.55552820067724	2.34278677756112e-05	0.00041551926596466
GO:0004536	DNA nuclease activity	24/2977	64/18639	0.375	2.34787537789721	2.4738794363948e-05	0.000426913452093351
GO:0140034	methylation-dependent protein binding	27/2977	76/18639	0.355263157894737	2.22430298958683	2.47389157830133e-05	0.000426913452093351
GO:0019104	DNA N-glycosylase activity	9/2977	13/18639	0.692307692307692	4.33453915919485	2.58209458613798e-05	0.00043385984032871
GO:0051011	microtubule minus-end binding	9/2977	13/18639	0.692307692307692	4.33453915919485	2.58209458613798e-05	0.00043385984032871
GO:0016860	intramolecular oxidoreductase activity	21/2977	53/18639	0.39622641509434	2.48077398419328	3.00381839789308e-05	0.000498165726507723
GO:0035064	methylated histone binding	26/2977	74/18639	0.351351351351351	2.19981116487667	4.32555046901236e-05	0.000708170249862665
GO:0016407	acetyltransferase activity	31/2977	96/18639	0.322916666666667	2.02178157541149	5.5031514315933e-05	0.000889560047866411
GO:0051536	iron-sulfur cluster binding	26/2977	76/18639	0.342105263157895	2.14192139737991	7.26203869452717e-05	0.0011592029266139
GO:0051540	metal cluster binding	26/2977	77/18639	0.337662337662338	2.11410423637498	9.31500128428923e-05	0.00146855020247375
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	15/2977	34/18639	0.441176470588235	2.7622063269379	9.61596163336287e-05	0.00149751012265907
GO:0005049	nuclear export signal receptor activity	8/2977	12/18639	0.666666666666667	4.17400067181727	0.000113124196034137	0.00174047708838063
GO:0004520	DNA endonuclease activity	17/2977	42/18639	0.404761904761905	2.53421469360334	0.000124017617179873	0.0018631823192788
GO:0031492	nucleosomal DNA binding	17/2977	42/18639	0.404761904761905	2.53421469360334	0.000124017617179873	0.0018631823192788
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	17/2977	43/18639	0.395348837209302	2.4752794681707	0.000174798209879625	0.00259555016298001
GO:0016874	ligase activity	45/2977	167/18639	0.269461077844311	1.68709607992614	0.000199233963099445	0.00292438817101139
GO:0003727	single-stranded RNA binding	28/2977	89/18639	0.314606741573034	1.96975312602613	0.000203750373237563	0.00295669575709509
GO:0003756	protein disulfide isomerase activity	10/2977	19/18639	0.526315789473684	3.29526368827679	0.000243266555905437	0.00345168213212492
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	10/2977	19/18639	0.526315789473684	3.29526368827679	0.000243266555905437	0.00345168213212492
GO:0031267	small GTPase binding	68/2977	283/18639	0.240282685512367	1.50441013613202	0.00026430796252823	0.00370902492470934
GO:0016922	nuclear receptor binding	38/2977	137/18639	0.277372262773723	1.73662801674149	0.000323033777558638	0.00448384928198239
GO:0051539	4 iron, 4 sulfur cluster binding	17/2977	45/18639	0.377777777777778	2.36526704736312	0.000332645436997925	0.00456761530157366
GO:0031490	chromatin DNA binding	36/2977	128/18639	0.28125	1.76090653342291	0.000342377113557683	0.00465122951077831
GO:0016835	carbon-oxygen lyase activity	25/2977	79/18639	0.316455696202532	1.98132943282465	0.000395147000937317	0.00531160758102057
GO:0140664	ATP-dependent DNA damage sensor activity	10/2977	20/18639	0.5	3.13050050386295	0.000417040928208149	0.00554751318043548
GO:0003725	double-stranded RNA binding	24/2977	75/18639	0.32	2.00352032247229	0.000426211336542771	0.00561105027592906
GO:0048027	mRNA 5'-UTR binding	11/2977	24/18639	0.458333333333333	2.86962546187437	0.000554524258831914	0.00715280281341772
GO:0140612	DNA damage sensor activity	11/2977	24/18639	0.458333333333333	2.86962546187437	0.000554524258831914	0.00715280281341772
GO:0140566	histone reader activity	14/2977	35/18639	0.4	2.50440040309036	0.00056055335848132	0.00715826638780646
GO:0016829	lyase activity	50/2977	200/18639	0.25	1.56525025193147	0.000630802594906698	0.00797559320490944
GO:0097718	disordered domain specific binding	12/2977	28/18639	0.428571428571429	2.68328614616824	0.000661940848120651	0.00828723983382423
GO:0051010	microtubule plus-end binding	10/2977	21/18639	0.476190476190476	2.98142905129805	0.00068264609939516	0.00846348610609339
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	20/2977	60/18639	0.333333333333333	2.08700033590863	0.000698651615221248	0.00857863569843782
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	15/2977	40/18639	0.375	2.34787537789721	0.000805228823540315	0.00972250747904245
GO:0016790	thiolester hydrolase activity	16/2977	44/18639	0.363636363636364	2.27672763917305	0.000807036642739624	0.00972250747904245
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	58/2977	243/18639	0.238683127572016	1.49439530225556	0.000852939535458019	0.0101794746428027
GO:0004676	3-phosphoinositide-dependent protein kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:0004711	ribosomal protein S6 kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:0035175	histone H3S10 kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:0035979	histone H2AXS139 kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:0044022	histone H3S28 kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:0044023	histone H4S1 kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:0044024	histone H2AS1 kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:0044025	histone H2BS14 kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:0072354	histone H3T3 kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:0072371	histone H2AS121 kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:0072518	Rho-dependent protein serine/threonine kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:0140823	histone H2BS36 kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:0140855	histone H3S57 kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:0140995	histone H2A kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:0140997	histone H4 kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:0140998	histone H2B kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:1990244	histone H2AT120 kinase activity	58/2977	245/18639	0.236734693877551	1.48219615693103	0.00105241249873311	0.0108361986960485
GO:0051082	unfolded protein binding	33/2977	121/18639	0.272727272727273	1.70754572937979	0.00106070856460929	0.0108361986960485
GO:0070034	telomerase RNA binding	10/2977	22/18639	0.454545454545455	2.84590954896632	0.00107338229205463	0.0108786443409028
GO:0004677	DNA-dependent protein kinase activity	58/2977	246/18639	0.235772357723577	1.47617096930123	0.00116685786969998	0.0116412304656787
GO:0140857	histone H3T45 kinase activity	58/2977	246/18639	0.235772357723577	1.47617096930123	0.00116685786969998	0.0116412304656787
GO:0017069	snRNA binding	18/2977	54/18639	0.333333333333333	2.08700033590863	0.00126988623947478	0.0124741902139177
GO:0051287	NAD binding	18/2977	54/18639	0.333333333333333	2.08700033590863	0.00126988623947478	0.0124741902139177
GO:0035402	histone H3T11 kinase activity	58/2977	247/18639	0.234817813765182	1.4701945686158	0.00129217820720586	0.0125008452318325
GO:0035403	histone H3T6 kinase activity	58/2977	247/18639	0.234817813765182	1.4701945686158	0.00129217820720586	0.0125008452318325
GO:0051020	GTPase binding	71/2977	315/18639	0.225396825396825	1.41120975094774	0.00132573715780765	0.0127290703046644
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	16/2977	46/18639	0.347826086956522	2.17773948094814	0.00139884984636411	0.0133308302522908
GO:0004679	AMP-activated protein kinase activity	58/2977	248/18639	0.233870967741935	1.46426636471009	0.00142923812765483	0.0135195339927053
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	21/2977	68/18639	0.308823529411765	1.93354442885653	0.00157959850043137	0.0148319653312564
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	54/2977	229/18639	0.235807860262009	1.47639325073012	0.00168135711122779	0.015672211905386
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	7/2977	13/18639	0.538461538461538	3.37130823492933	0.00184830127899635	0.0171034835744807
GO:0032182	ubiquitin-like protein binding	32/2977	120/18639	0.266666666666667	1.66960026872691	0.00186650841759313	0.0171477068292549
GO:0008641	ubiquitin-like modifier activating enzyme activity	6/2977	10/18639	0.6	3.75660060463554	0.00193459827333038	0.0172394155093952
GO:0016427	tRNA (cytidine) methyltransferase activity	6/2977	10/18639	0.6	3.75660060463554	0.00193459827333038	0.0172394155093952
GO:0047429	nucleoside triphosphate diphosphatase activity	6/2977	10/18639	0.6	3.75660060463554	0.00193459827333038	0.0172394155093952
GO:0051880	G-quadruplex DNA binding	6/2977	10/18639	0.6	3.75660060463554	0.00193459827333038	0.0172394155093952
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	14/2977	39/18639	0.358974358974359	2.24753882328622	0.00194399047247683	0.0172394155093952
GO:0061608	nuclear import signal receptor activity	9/2977	20/18639	0.45	2.81745045347665	0.0020832480314194	0.0183469499042936
GO:0070840	dynein complex binding	10/2977	24/18639	0.416666666666667	2.60875041988579	0.00239690283300225	0.0209646912174238
GO:0180051	translation factor activity	24/2977	84/18639	0.285714285714286	1.78885743077883	0.00248161826632317	0.0215580035788755
GO:0019783	ubiquitin-like protein peptidase activity	33/2977	127/18639	0.259842519685039	1.62687427759807	0.00253067334967192	0.0218356072130476
GO:0070717	poly-purine tract binding	12/2977	32/18639	0.375	2.34787537789721	0.00263904973758964	0.0226178960731676
GO:0070182	DNA polymerase binding	9/2977	21/18639	0.428571428571429	2.68328614616824	0.00313369948043758	0.0266782282434586
GO:0030983	mismatched DNA binding	7/2977	14/18639	0.5	3.13050050386295	0.00318938475990094	0.0267950285420625
GO:0098847	sequence-specific single stranded DNA binding	7/2977	14/18639	0.5	3.13050050386295	0.00318938475990094	0.0267950285420625
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	10/2977	25/18639	0.4	2.50440040309036	0.00342938702777771	0.0286230538200793
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	12/2977	33/18639	0.363636363636364	2.27672763917305	0.00355254647933469	0.0294584535981195
GO:0032404	mismatch repair complex binding	6/2977	11/18639	0.545454545454545	3.41509145875958	0.00368233413148173	0.0301432095250139
GO:0070990	snRNP binding	6/2977	11/18639	0.545454545454545	3.41509145875958	0.00368233413148173	0.0301432095250139
GO:1990841	promoter-specific chromatin binding	20/2977	68/18639	0.294117647058824	1.84147088462526	0.00380795123189819	0.0309729536505349
GO:0008409	5'-3' exonuclease activity	8/2977	18/18639	0.444444444444444	2.78266711454484	0.00405584306592003	0.0325337893667642
GO:0070628	proteasome binding	8/2977	18/18639	0.444444444444444	2.78266711454484	0.00405584306592003	0.0325337893667642
GO:0106310	protein serine kinase activity	77/2977	361/18639	0.213296398891967	1.33544896840691	0.00408504508754065	0.0325337893667642
GO:0004521	RNA endonuclease activity	21/2977	73/18639	0.287671232876712	1.80110987893485	0.00410175418014803	0.0325337893667642
GO:0140517	protein-RNA adaptor activity	9/2977	22/18639	0.409090909090909	2.56131859406969	0.00456007291854885	0.0359457599814005
GO:0008135	translation factor activity, RNA binding	23/2977	83/18639	0.27710843373494	1.7349761828638	0.00459056044366225	0.0359640839666055
GO:0015035	protein-disulfide reductase activity	12/2977	34/18639	0.352941176470588	2.20976506155032	0.00470443317214627	0.0366314704928707
GO:0004529	DNA exonuclease activity	10/2977	26/18639	0.384615384615385	2.40807731066381	0.00478549669285267	0.0370202165314504
GO:0008187	poly-pyrimidine tract binding	11/2977	30/18639	0.366666666666667	2.2957003694995	0.00481233824919402	0.0370202165314504
GO:0004843	cysteine-type deubiquitinase activity	28/2977	108/18639	0.259259259259259	1.62322248348449	0.00530545656331266	0.040569269648804
GO:0022853	active monoatomic ion transmembrane transporter activity	30/2977	118/18639	0.254237288135593	1.59177991721845	0.00542862011854565	0.0412639755439452
GO:0008301	DNA binding, bending	8/2977	19/18639	0.421052631578947	2.63621095062143	0.00603576177933508	0.0453392223071229
GO:0008574	plus-end-directed microtubule motor activity	8/2977	19/18639	0.421052631578947	2.63621095062143	0.00603576177933508	0.0453392223071229
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	15/2977	48/18639	0.3125	1.95656281491434	0.00622206847339605	0.0464653885410922
GO:0003995	acyl-CoA dehydrogenase activity	6/2977	12/18639	0.5	3.13050050386295	0.00637547799772099	0.0467901459947684
GO:0043047	single-stranded telomeric DNA binding	6/2977	12/18639	0.5	3.13050050386295	0.00637547799772099	0.0467901459947684
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	6/2977	12/18639	0.5	3.13050050386295	0.00637547799772099	0.0467901459947684
GO:0070577	lysine-acetylated histone binding	9/2977	23/18639	0.391304347826087	2.44995691606666	0.00644417652019587	0.047024076664515
GO:0043130	ubiquitin binding	26/2977	100/18639	0.26	1.62786026200873	0.00677089942286127	0.0491274918351923
GO:0101005	deubiquitinase activity	29/2977	115/18639	0.252173913043478	1.5788611236874	0.00698014260307676	0.0503595599103335
GO:0015399	primary active transmembrane transporter activity	39/2977	166/18639	0.234939759036145	1.47095806808018	0.00726865961965081	0.0521394043088009
GO:0015036	disulfide oxidoreductase activity	13/2977	40/18639	0.325	2.03482532751092	0.00734932872011289	0.0521394043088009
GO:0140662	ATP-dependent protein folding chaperone	13/2977	40/18639	0.325	2.03482532751092	0.00734932872011289	0.0521394043088009
GO:0008234	cysteine-type peptidase activity	43/2977	187/18639	0.229946524064171	1.43969541888884	0.00746743537085168	0.052684613086064
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	12/2977	36/18639	0.333333333333333	2.08700033590863	0.00789065488453254	0.0547072912733475
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	12/2977	36/18639	0.333333333333333	2.08700033590863	0.00789065488453254	0.0547072912733475
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	12/2977	36/18639	0.333333333333333	2.08700033590863	0.00789065488453254	0.0547072912733475
GO:0043023	ribosomal large subunit binding	7/2977	16/18639	0.4375	2.73918794088008	0.00792548855565333	0.0547072912733475
GO:0051059	NF-kappaB binding	11/2977	32/18639	0.34375	2.15221909640578	0.00836980964104564	0.0574636930732004
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	16/2977	54/18639	0.296296296296296	1.85511140969656	0.00844335103378967	0.0576586057227241
GO:0000339	RNA cap binding	8/2977	20/18639	0.4	2.50440040309036	0.0086707709446122	0.0588966728524988
GO:0140033	acetylation-dependent protein binding	9/2977	24/18639	0.375	2.34787537789721	0.008872540732512	0.0599483307694064
GO:0004197	cysteine-type endopeptidase activity	23/2977	88/18639	0.261363636363636	1.63639799065563	0.00978649957232813	0.0657755787045422
GO:0008170	N-methyltransferase activity	25/2977	98/18639	0.255102040816327	1.59719413462395	0.0100445125623421	0.0668204269974463
GO:0002039	p53 binding	19/2977	69/18639	0.27536231884058	1.72404375575061	0.0101427742907564	0.0668204269974463
GO:0005542	folic acid binding	6/2977	13/18639	0.461538461538462	2.88969277279657	0.0102559151851993	0.0668204269974463
GO:0009982	pseudouridine synthase activity	6/2977	13/18639	0.461538461538462	2.88969277279657	0.0102559151851993	0.0668204269974463
GO:0140666	annealing activity	6/2977	13/18639	0.461538461538462	2.88969277279657	0.0102559151851993	0.0668204269974463
GO:0140852	histone ubiquitin ligase activity	6/2977	13/18639	0.461538461538462	2.88969277279657	0.0102559151851993	0.0668204269974463
GO:0004860	protein kinase inhibitor activity	22/2977	84/18639	0.261904761904762	1.63978597821393	0.0110735472126464	0.0717813187337537
GO:0003743	translation initiation factor activity	15/2977	51/18639	0.294117647058824	1.84147088462526	0.0113624337741164	0.0730607425739594
GO:0160215	deacylase activity	18/2977	65/18639	0.276923076923077	1.73381566367794	0.0114275350034369	0.0730607425739594
GO:0016859	cis-trans isomerase activity	13/2977	42/18639	0.30952380952381	1.93792888334373	0.0114425595260704	0.0730607425739594
GO:0004549	tRNA-specific ribonuclease activity	7/2977	17/18639	0.411764705882353	2.57805923847537	0.0116418649512084	0.0732347859245969
GO:0046965	nuclear retinoid X receptor binding	7/2977	17/18639	0.411764705882353	2.57805923847537	0.0116418649512084	0.0732347859245969
GO:0070402	NADPH binding	7/2977	17/18639	0.411764705882353	2.57805923847537	0.0116418649512084	0.0732347859245969
GO:0042974	nuclear retinoic acid receptor binding	9/2977	25/18639	0.36	2.25396036278132	0.0119343146914251	0.0743420481021941
GO:0047617	fatty acyl-CoA hydrolase activity	9/2977	25/18639	0.36	2.25396036278132	0.0119343146914251	0.0743420481021941
GO:0140312	cargo adaptor activity	8/2977	21/18639	0.380952380952381	2.38514324103844	0.0120781995379504	0.0748731107279743
GO:0004674	protein serine/threonine kinase activity	87/2977	433/18639	0.200923787528868	1.25798403619435	0.012322820666565	0.0760204927111278
GO:0001221	transcription coregulator binding	28/2977	115/18639	0.243478260869565	1.5244176366637	0.0128807984305745	0.0769165923090348
GO:0019210	kinase inhibitor activity	23/2977	90/18639	0.255555555555556	1.60003359086329	0.0128866977373164	0.0769165923090348
GO:0001094	TFIID-class transcription factor complex binding	5/2977	10/18639	0.5	3.13050050386295	0.0128897030181155	0.0769165923090348
GO:0004862	cAMP-dependent protein kinase inhibitor activity	5/2977	10/18639	0.5	3.13050050386295	0.0128897030181155	0.0769165923090348
GO:0031720	haptoglobin binding	5/2977	10/18639	0.5	3.13050050386295	0.0128897030181155	0.0769165923090348
GO:0033204	ribonuclease P RNA binding	5/2977	10/18639	0.5	3.13050050386295	0.0128897030181155	0.0769165923090348
GO:0098505	G-rich strand telomeric DNA binding	5/2977	10/18639	0.5	3.13050050386295	0.0128897030181155	0.0769165923090348
GO:0008276	protein methyltransferase activity	24/2977	95/18639	0.252631578947368	1.58172657037286	0.012972969230933	0.0770534032925649
GO:0016779	nucleotidyltransferase activity	32/2977	136/18639	0.235294117647059	1.47317670770021	0.013716600728003	0.0810930515262027
GO:0035925	mRNA 3'-UTR AU-rich region binding	10/2977	30/18639	0.333333333333333	2.08700033590863	0.0147692676255991	0.0869140772252999
GO:0016879	ligase activity, forming carbon-nitrogen bonds	14/2977	48/18639	0.291666666666667	1.82612529392005	0.0153045019274323	0.0896506833088579
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	12/2977	39/18639	0.307692307692308	1.92646184853105	0.0155620627576795	0.0907431695961494
GO:0008143	poly(A) binding	9/2977	26/18639	0.346153846153846	2.16726957959743	0.0157189830436105	0.0908286938764282
GO:0016289	acyl-CoA hydrolase activity	9/2977	26/18639	0.346153846153846	2.16726957959743	0.0157189830436105	0.0908286938764282
GO:0140296	general transcription initiation factor binding	15/2977	53/18639	0.283018867924528	1.77198141728091	0.0163187987419662	0.0922427139562273
GO:0019887	protein kinase regulator activity	54/2977	255/18639	0.211764705882353	1.32585903693019	0.0163642669154398	0.0922427139562273
GO:0034062	5'-3' RNA polymerase activity	8/2977	22/18639	0.363636363636364	2.27672763917305	0.0163742718918942	0.0922427139562273
GO:0097747	RNA polymerase activity	8/2977	22/18639	0.363636363636364	2.27672763917305	0.0163742718918942	0.0922427139562273
GO:0140035	ubiquitin-like protein reader activity	8/2977	22/18639	0.363636363636364	2.27672763917305	0.0163742718918942	0.0922427139562273
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	7/2977	18/18639	0.388888888888889	2.43483372522674	0.0164693334236647	0.0922427139562273
GO:0098641	cadherin binding involved in cell-cell adhesion	7/2977	18/18639	0.388888888888889	2.43483372522674	0.0164693334236647	0.0922427139562273
GO:0001046	core promoter sequence-specific DNA binding	13/2977	44/18639	0.295454545454545	1.84984120682811	0.0171088939583114	0.093552219734368
GO:0003954	NADH dehydrogenase activity	13/2977	44/18639	0.295454545454545	1.84984120682811	0.0171088939583114	0.093552219734368
GO:0019205	nucleobase-containing compound kinase activity	13/2977	44/18639	0.295454545454545	1.84984120682811	0.0171088939583114	0.093552219734368
GO:0030020	extracellular matrix structural constituent conferring tensile strength	13/2977	44/18639	0.295454545454545	1.84984120682811	0.0171088939583114	0.093552219734368
GO:0010485	histone H4 acetyltransferase activity	11/2977	35/18639	0.314285714285714	1.96774317385671	0.0171426933577464	0.093552219734368
GO:0043015	gamma-tubulin binding	11/2977	35/18639	0.314285714285714	1.96774317385671	0.0171426933577464	0.093552219734368
GO:0003777	microtubule motor activity	18/2977	68/18639	0.264705882352941	1.65732379616274	0.0182352630024573	0.0986713171785506
GO:0030145	manganese ion binding	18/2977	68/18639	0.264705882352941	1.65732379616274	0.0182352630024573	0.0986713171785506
GO:0030331	nuclear estrogen receptor binding	12/2977	40/18639	0.3	1.87830030231777	0.0190818059166366	0.102816312892595
GO:0070063	RNA polymerase binding	16/2977	59/18639	0.271186440677966	1.69789857836635	0.0201123561873259	0.107913776685778
GO:0008266	poly(U) RNA binding	9/2977	27/18639	0.333333333333333	2.08700033590863	0.0203140078638331	0.108505478557822
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	5/2977	11/18639	0.454545454545455	2.84590954896632	0.0205625104236436	0.108505478557822
GO:0034511	U3 snoRNA binding	5/2977	11/18639	0.454545454545455	2.84590954896632	0.0205625104236436	0.108505478557822
GO:0048407	platelet-derived growth factor binding	5/2977	11/18639	0.454545454545455	2.84590954896632	0.0205625104236436	0.108505478557822
GO:0046332	SMAD binding	20/2977	79/18639	0.253164556962025	1.58506354625972	0.0215074936268842	0.11249187870095
GO:0003887	DNA-directed DNA polymerase activity	8/2977	23/18639	0.347826086956522	2.17773948094814	0.0216703227568	0.11249187870095
GO:0008171	O-methyltransferase activity	8/2977	23/18639	0.347826086956522	2.17773948094814	0.0216703227568	0.11249187870095
GO:0017134	fibroblast growth factor binding	8/2977	23/18639	0.347826086956522	2.17773948094814	0.0216703227568	0.11249187870095
GO:0008252	nucleotidase activity	6/2977	15/18639	0.4	2.50440040309036	0.0224849966367756	0.115676627280087
GO:0061578	K63-linked deubiquitinase activity	6/2977	15/18639	0.4	2.50440040309036	0.0224849966367756	0.115676627280087
GO:0046527	glucosyltransferase activity	7/2977	19/18639	0.368421052631579	2.30668458179375	0.0225555835495236	0.115676627280087
GO:0098632	cell-cell adhesion mediator activity	15/2977	55/18639	0.272727272727273	1.70754572937979	0.0227852761957026	0.115923496820367
GO:0140313	molecular sequestering activity	15/2977	55/18639	0.272727272727273	1.70754572937979	0.0227852761957026	0.115923496820367
GO:0008137	NADH dehydrogenase (ubiquinone) activity	12/2977	41/18639	0.292682926829268	1.83248809982221	0.0231626826821384	0.117375975337661
GO:0035173	histone kinase activity	72/2977	360/18639	0.2	1.25220020154518	0.0233013440015247	0.117563740759131
GO:0001098	basal transcription machinery binding	16/2977	60/18639	0.266666666666667	1.66960026872691	0.0234759231742979	0.117563740759131
GO:0001099	basal RNA polymerase II transcription machinery binding	16/2977	60/18639	0.266666666666667	1.66960026872691	0.0234759231742979	0.117563740759131
GO:0031072	heat shock protein binding	30/2977	131/18639	0.229007633587786	1.43381702467005	0.0237575096689023	0.118509140028079
GO:0044183	protein folding chaperone	19/2977	75/18639	0.253333333333333	1.58612025529056	0.0244482711470197	0.12148032005737
GO:0009055	electron transfer activity	27/2977	116/18639	0.232758620689655	1.45730195869482	0.0253215185722894	0.12533170239075
GO:0046966	nuclear thyroid hormone receptor binding	9/2977	28/18639	0.321428571428571	2.01246460962618	0.0258024967384815	0.126729955134773
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	9/2977	28/18639	0.321428571428571	2.01246460962618	0.0258024967384815	0.126729955134773
GO:0016836	hydro-lyase activity	16/2977	61/18639	0.262295081967213	1.64222977251827	0.0272459279612458	0.133306705005789
GO:0004402	histone acetyltransferase activity	12/2977	42/18639	0.285714285714286	1.78885743077883	0.0278507319445655	0.134789294148566
GO:0048487	beta-tubulin binding	12/2977	42/18639	0.285714285714286	1.78885743077883	0.0278507319445655	0.134789294148566
GO:0098631	cell adhesion mediator activity	19/2977	76/18639	0.25	1.56525025193147	0.0278656019226478	0.134789294148566
GO:0070300	phosphatidic acid binding	8/2977	24/18639	0.333333333333333	2.08700033590863	0.0280692137689439	0.135261833897892
GO:0061733	protein-lysine-acetyltransferase activity	13/2977	47/18639	0.276595744680851	1.7317662361795	0.0292718586826302	0.140000612500819
GO:0140938	histone H3 methyltransferase activity	13/2977	47/18639	0.276595744680851	1.7317662361795	0.0292718586826302	0.140000612500819
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	7/2977	20/18639	0.35	2.19135035270406	0.0300320211060144	0.143100339374554
GO:0000340	RNA 7-methylguanosine cap binding	5/2977	12/18639	0.416666666666667	2.60875041988579	0.0306961050135883	0.143585809898726
GO:0000995	RNA polymerase III general transcription initiation factor activity	5/2977	12/18639	0.416666666666667	2.60875041988579	0.0306961050135883	0.143585809898726
GO:0004526	ribonuclease P activity	5/2977	12/18639	0.416666666666667	2.60875041988579	0.0306961050135883	0.143585809898726
GO:0008603	cAMP-dependent protein kinase regulator activity	5/2977	12/18639	0.416666666666667	2.60875041988579	0.0306961050135883	0.143585809898726
GO:0035259	nuclear glucocorticoid receptor binding	5/2977	12/18639	0.416666666666667	2.60875041988579	0.0306961050135883	0.143585809898726
GO:0004601	peroxidase activity	15/2977	57/18639	0.263157894736842	1.64763184413839	0.0310061018381423	0.144506540318641
GO:0000062	fatty-acyl-CoA binding	6/2977	16/18639	0.375	2.34787537789721	0.0312207014854489	0.144977584716067
GO:0034212	protein N-acetyltransferase activity	14/2977	53/18639	0.264150943396226	1.65384932279552	0.0353189118165746	0.163413950687557
GO:0061980	regulatory RNA binding	15/2977	58/18639	0.258620689655172	1.6192243985498	0.0358471625091501	0.165259301531353
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	7/2977	21/18639	0.333333333333333	2.08700033590863	0.0390089318900465	0.179188510876221
GO:0001222	transcription corepressor binding	13/2977	49/18639	0.26530612244898	1.66108190000891	0.0402740835260389	0.184336934275096
GO:0008080	N-acetyltransferase activity	17/2977	69/18639	0.246376811594203	1.5425654656716	0.0410794285981342	0.186619969548571
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	15/2977	59/18639	0.254237288135593	1.59177991721845	0.0412113010279539	0.186619969548571
GO:0036002	pre-mRNA binding	15/2977	59/18639	0.254237288135593	1.59177991721845	0.0412113010279539	0.186619969548571
GO:0017110	nucleoside diphosphate phosphatase activity	6/2977	17/18639	0.352941176470588	2.20976506155032	0.041900066867762	0.188402765458212
GO:1901567	fatty acid derivative binding	6/2977	17/18639	0.352941176470588	2.20976506155032	0.041900066867762	0.188402765458212
GO:0141003	histone H2AX kinase activity	69/2977	354/18639	0.194915254237288	1.22036460320081	0.0425157682762239	0.190500477504344
GO:0034061	DNA polymerase activity	10/2977	35/18639	0.285714285714286	1.78885743077883	0.0426684656706871	0.190516191124012
GO:0008253	5'-nucleotidase activity	5/2977	13/18639	0.384615384615385	2.40807731066381	0.0434712236563314	0.192085649166558
GO:0043560	insulin receptor substrate binding	5/2977	13/18639	0.384615384615385	2.40807731066381	0.0434712236563314	0.192085649166558
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	5/2977	13/18639	0.384615384615385	2.40807731066381	0.0434712236563314	0.192085649166558
GO:0050681	nuclear androgen receptor binding	8/2977	26/18639	0.307692307692308	1.92646184853105	0.0445257183008698	0.195077638770122
GO:0070412	R-SMAD binding	8/2977	26/18639	0.307692307692308	1.92646184853105	0.0445257183008698	0.195077638770122
GO:0019207	kinase regulator activity	57/2977	287/18639	0.198606271777003	1.2434740677365	0.044606633140858	0.195077638770122
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	27/2977	122/18639	0.221311475409836	1.38563137056229	0.0452857678926199	0.197371759723125
GO:0070273	phosphatidylinositol-4-phosphate binding	9/2977	31/18639	0.290322580645161	1.81770996998494	0.0483494721788619	0.210007741402744
GO:0004407	histone deacetylase activity	7/2977	22/18639	0.318181818181818	1.99213668427642	0.0495717732225175	0.211881537869966
GO:0008649	rRNA methyltransferase activity	7/2977	22/18639	0.318181818181818	1.99213668427642	0.0495717732225175	0.211881537869966
GO:0033558	protein lysine deacetylase activity	7/2977	22/18639	0.318181818181818	1.99213668427642	0.0495717732225175	0.211881537869966
GO:0140996	histone H3 kinase activity	69/2977	357/18639	0.19327731092437	1.21010943846803	0.0495818373301379	0.211881537869966
GO:0019842	vitamin binding	32/2977	150/18639	0.213333333333333	1.33568021498153	0.0496104775435551	0.211881537869966
GO:0004842	ubiquitin-protein transferase activity	85/2977	449/18639	0.189309576837416	1.18526745135123	0.0500263557732553	0.212945521074823
GO:0000993	RNA polymerase II complex binding	10/2977	36/18639	0.277777777777778	1.73916694659053	0.0509203408186589	0.216030814702416
GO:0016755	aminoacyltransferase activity	93/2977	496/18639	0.1875	1.17393768894861	0.0516822600414722	0.218537238652185
GO:0140299	molecular sensor activity	17/2977	71/18639	0.23943661971831	1.49911291734282	0.0523412539000501	0.218623301226919
GO:0019787	ubiquitin-like protein transferase activity	90/2977	479/18639	0.187891440501044	1.17638849832011	0.0525136846191595	0.218623301226919
GO:0004812	aminoacyl-tRNA ligase activity	11/2977	41/18639	0.268292682926829	1.67978075817036	0.0525586166614442	0.218623301226919
GO:0016875	ligase activity, forming carbon-oxygen bonds	11/2977	41/18639	0.268292682926829	1.67978075817036	0.0525586166614442	0.218623301226919
GO:0016877	ligase activity, forming carbon-sulfur bonds	11/2977	41/18639	0.268292682926829	1.67978075817036	0.0525586166614442	0.218623301226919
GO:0030291	protein serine/threonine kinase inhibitor activity	12/2977	46/18639	0.260869565217391	1.6333046107111	0.0534967107389203	0.220817102078
GO:0052689	carboxylic ester hydrolase activity	21/2977	92/18639	0.228260869565217	1.42914153437222	0.0535959782937936	0.220817102078
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	15/2977	61/18639	0.245901639344262	1.53959041173588	0.0536047781082067	0.220817102078
GO:0003746	translation elongation factor activity	6/2977	18/18639	0.333333333333333	2.08700033590863	0.0546154335898106	0.223538168891629
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	6/2977	18/18639	0.333333333333333	2.08700033590863	0.0546154335898106	0.223538168891629
GO:0043425	bHLH transcription factor binding	9/2977	32/18639	0.28125	1.76090653342291	0.0580829206676371	0.233102142159951
GO:0005344	oxygen carrier activity	5/2977	14/18639	0.357142857142857	2.23607178847354	0.0589797851297528	0.233102142159951
GO:0008474	palmitoyl-(protein) hydrolase activity	5/2977	14/18639	0.357142857142857	2.23607178847354	0.0589797851297528	0.233102142159951
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	5/2977	14/18639	0.357142857142857	2.23607178847354	0.0589797851297528	0.233102142159951
GO:0034236	protein kinase A catalytic subunit binding	5/2977	14/18639	0.357142857142857	2.23607178847354	0.0589797851297528	0.233102142159951
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	5/2977	14/18639	0.357142857142857	2.23607178847354	0.0589797851297528	0.233102142159951
GO:0098599	palmitoyl hydrolase activity	5/2977	14/18639	0.357142857142857	2.23607178847354	0.0589797851297528	0.233102142159951
GO:1990825	sequence-specific mRNA binding	5/2977	14/18639	0.357142857142857	2.23607178847354	0.0589797851297528	0.233102142159951
GO:0042054	histone methyltransferase activity	16/2977	67/18639	0.238805970149254	1.49516441975544	0.0597737869047358	0.233102142159951
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	4/2977	10/18639	0.4	2.50440040309036	0.0609679839322034	0.233102142159951
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	4/2977	10/18639	0.4	2.50440040309036	0.0609679839322034	0.233102142159951
GO:0008519	ammonium channel activity	4/2977	10/18639	0.4	2.50440040309036	0.0609679839322034	0.233102142159951
GO:0016783	sulfurtransferase activity	4/2977	10/18639	0.4	2.50440040309036	0.0609679839322034	0.233102142159951
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	4/2977	10/18639	0.4	2.50440040309036	0.0609679839322034	0.233102142159951
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	4/2977	10/18639	0.4	2.50440040309036	0.0609679839322034	0.233102142159951
GO:0031419	cobalamin binding	4/2977	10/18639	0.4	2.50440040309036	0.0609679839322034	0.233102142159951
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	4/2977	10/18639	0.4	2.50440040309036	0.0609679839322034	0.233102142159951
GO:0050815	phosphoserine residue binding	4/2977	10/18639	0.4	2.50440040309036	0.0609679839322034	0.233102142159951
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	4/2977	10/18639	0.4	2.50440040309036	0.0609679839322034	0.233102142159951
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	4/2977	10/18639	0.4	2.50440040309036	0.0609679839322034	0.233102142159951
GO:1905394	retromer complex binding	4/2977	10/18639	0.4	2.50440040309036	0.0609679839322034	0.233102142159951
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	4/2977	10/18639	0.4	2.50440040309036	0.0609679839322034	0.233102142159951
GO:0035198	miRNA binding	11/2977	42/18639	0.261904761904762	1.63978597821393	0.0613259305932397	0.233406349148581
GO:0042171	lysophosphatidic acid acyltransferase activity	7/2977	23/18639	0.304347826086957	1.90552204582962	0.0617786578012688	0.233406349148581
GO:0071617	lysophospholipid acyltransferase activity	7/2977	23/18639	0.304347826086957	1.90552204582962	0.0617786578012688	0.233406349148581
GO:0140102	catalytic activity, acting on a rRNA	7/2977	23/18639	0.304347826086957	1.90552204582962	0.0617786578012688	0.233406349148581
GO:0003774	cytoskeletal motor activity	32/2977	153/18639	0.209150326797386	1.30949040684463	0.0624379479141627	0.235201355417067
GO:0051015	actin filament binding	42/2977	209/18639	0.200956937799043	1.25819159006932	0.0647097119560654	0.243042065199693
GO:0043539	protein serine/threonine kinase activator activity	17/2977	73/18639	0.232876712328767	1.4580413305663	0.0656005410951004	0.24566536943825
GO:0016866	intramolecular transferase activity	8/2977	28/18639	0.285714285714286	1.78885743077883	0.0662871730781836	0.24751087725392
GO:0140416	transcription regulator inhibitor activity	9/2977	33/18639	0.272727272727273	1.70754572937979	0.068990743953924	0.255715474351397
GO:0042826	histone deacetylase binding	27/2977	127/18639	0.21259842519685	1.33107895439842	0.0692356106227205	0.255715474351397
GO:0120227	acyl-CoA binding	6/2977	19/18639	0.315789473684211	1.97715821296607	0.0694122874545584	0.255715474351397
GO:0140036	ubiquitin-modified protein reader activity	6/2977	19/18639	0.315789473684211	1.97715821296607	0.0694122874545584	0.255715474351397
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	14/2977	58/18639	0.241379310344828	1.51127610531315	0.0694857240406694	0.255715474351397
GO:0051018	protein kinase A binding	13/2977	53/18639	0.245283018867925	1.53571722831013	0.0703707229831107	0.257738575353043
GO:0043531	ADP binding	10/2977	38/18639	0.263157894736842	1.64763184413839	0.0704391251356398	0.257738575353043
GO:0016757	glycosyltransferase activity	52/2977	267/18639	0.194756554307116	1.21937098277808	0.07078215397388	0.258253744641842
GO:0048029	monosaccharide binding	17/2977	74/18639	0.22972972972973	1.43833806934244	0.0730144167568396	0.265639345294827
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	27/2977	128/18639	0.2109375	1.32067990006718	0.0749193957038447	0.271795648618778
GO:0001091	RNA polymerase II general transcription initiation factor binding	7/2977	24/18639	0.291666666666667	1.82612529392005	0.0756590171086966	0.272159337599452
GO:0043998	histone H2A acetyltransferase activity	7/2977	24/18639	0.291666666666667	1.82612529392005	0.0756590171086966	0.272159337599452
GO:0050699	WW domain binding	7/2977	24/18639	0.291666666666667	1.82612529392005	0.0756590171086966	0.272159337599452
GO:0000774	adenyl-nucleotide exchange factor activity	5/2977	15/18639	0.333333333333333	2.08700033590863	0.0772271793762415	0.27318312482953
GO:0004129	cytochrome-c oxidase activity	5/2977	15/18639	0.333333333333333	2.08700033590863	0.0772271793762415	0.27318312482953
GO:0004559	alpha-mannosidase activity	5/2977	15/18639	0.333333333333333	2.08700033590863	0.0772271793762415	0.27318312482953
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	5/2977	15/18639	0.333333333333333	2.08700033590863	0.0772271793762415	0.27318312482953
GO:0042809	nuclear vitamin D receptor binding	5/2977	15/18639	0.333333333333333	2.08700033590863	0.0772271793762415	0.27318312482953
GO:0140776	protein-containing complex destabilizing activity	5/2977	15/18639	0.333333333333333	2.08700033590863	0.0772271793762415	0.27318312482953
GO:0106222	lncRNA binding	8/2977	29/18639	0.275862068965517	1.72717269178645	0.0792495288238765	0.27956256438699
GO:0050661	NADP binding	13/2977	54/18639	0.240740740740741	1.50727802037846	0.0797123099139599	0.280420440110542
GO:0060590	ATPase regulator activity	12/2977	49/18639	0.244897959183673	1.533306369239	0.080854697186308	0.283020525282843
GO:0030332	cyclin binding	9/2977	34/18639	0.264705882352941	1.65732379616274	0.0810922721452204	0.283020525282843
GO:0003779	actin binding	82/2977	443/18639	0.18510158013544	1.15892117975965	0.0811162977709637	0.283020525282843
GO:0015078	proton transmembrane transporter activity	37/2977	185/18639	0.2	1.25220020154518	0.0832496816993041	0.284722988651645
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	4/2977	11/18639	0.363636363636364	2.27672763917305	0.0840568259370948	0.284722988651645
GO:0004523	RNA-DNA hybrid ribonuclease activity	4/2977	11/18639	0.363636363636364	2.27672763917305	0.0840568259370948	0.284722988651645
GO:0005536	D-glucose binding	4/2977	11/18639	0.363636363636364	2.27672763917305	0.0840568259370948	0.284722988651645
GO:0008172	S-methyltransferase activity	4/2977	11/18639	0.363636363636364	2.27672763917305	0.0840568259370948	0.284722988651645
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	4/2977	11/18639	0.363636363636364	2.27672763917305	0.0840568259370948	0.284722988651645
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	4/2977	11/18639	0.363636363636364	2.27672763917305	0.0840568259370948	0.284722988651645
GO:0019206	nucleoside kinase activity	4/2977	11/18639	0.363636363636364	2.27672763917305	0.0840568259370948	0.284722988651645
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	4/2977	11/18639	0.363636363636364	2.27672763917305	0.0840568259370948	0.284722988651645
GO:0032794	GTPase activating protein binding	4/2977	11/18639	0.363636363636364	2.27672763917305	0.0840568259370948	0.284722988651645
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	4/2977	11/18639	0.363636363636364	2.27672763917305	0.0840568259370948	0.284722988651645
GO:0019843	rRNA binding	15/2977	65/18639	0.230769230769231	1.44484638639828	0.0855765928876091	0.289103992374277
GO:0016408	C-acyltransferase activity	6/2977	20/18639	0.3	1.87830030231777	0.0862895444610773	0.290743399147218
GO:0008374	O-acyltransferase activity	13/2977	55/18639	0.236363636363636	1.47987296546248	0.0898074278279543	0.301800224569204
GO:0008139	nuclear localization sequence binding	7/2977	25/18639	0.28	1.75308028216325	0.0912133708638912	0.305720405756402
GO:0001968	fibronectin binding	8/2977	30/18639	0.266666666666667	1.66960026872691	0.0936102878985021	0.312115764089784
GO:0016769	transferase activity, transferring nitrogenous groups	8/2977	30/18639	0.266666666666667	1.66960026872691	0.0936102878985021	0.312115764089784
GO:0005521	lamin binding	5/2977	16/18639	0.3125	1.95656281491434	0.0981392147811471	0.321343018655192
GO:0008296	3'-5'-DNA exonuclease activity	5/2977	16/18639	0.3125	1.95656281491434	0.0981392147811471	0.321343018655192
GO:0015923	mannosidase activity	5/2977	16/18639	0.3125	1.95656281491434	0.0981392147811471	0.321343018655192
GO:0016675	oxidoreductase activity, acting on a heme group of donors	5/2977	16/18639	0.3125	1.95656281491434	0.0981392147811471	0.321343018655192
GO:0017070	U6 snRNA binding	5/2977	16/18639	0.3125	1.95656281491434	0.0981392147811471	0.321343018655192
GO:0070411	I-SMAD binding	5/2977	16/18639	0.3125	1.95656281491434	0.0981392147811471	0.321343018655192
GO:0140328	floppase activity	5/2977	16/18639	0.3125	1.95656281491434	0.0981392147811471	0.321343018655192
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	27/2977	132/18639	0.204545454545455	1.28065929703484	0.100817664760426	0.329268946033413
GO:0008373	sialyltransferase activity	6/2977	21/18639	0.285714285714286	1.78885743077883	0.10520178948949	0.341838893582896
GO:1904047	S-adenosyl-L-methionine binding	6/2977	21/18639	0.285714285714286	1.78885743077883	0.10520178948949	0.341838893582896
GO:0042169	SH2 domain binding	10/2977	41/18639	0.24390243902439	1.52707341651851	0.107514634357277	0.344905822027631
GO:0008198	ferrous iron binding	7/2977	26/18639	0.269230769230769	1.68565411746466	0.108414084966057	0.344905822027631
GO:0044390	ubiquitin-like protein conjugating enzyme binding	9/2977	36/18639	0.25	1.56525025193147	0.108883647114115	0.344905822027631
GO:0055106	ubiquitin-protein transferase regulator activity	9/2977	36/18639	0.25	1.56525025193147	0.108883647114115	0.344905822027631
GO:0016411	acylglycerol O-acyltransferase activity	8/2977	31/18639	0.258064516129032	1.61574219554217	0.109353180322725	0.344905822027631
GO:0072349	modified amino acid transmembrane transporter activity	8/2977	31/18639	0.258064516129032	1.61574219554217	0.109353180322725	0.344905822027631
GO:0005095	GTPase inhibitor activity	4/2977	12/18639	0.333333333333333	2.08700033590863	0.110737186398848	0.344905822027631
GO:0016801	hydrolase activity, acting on ether bonds	4/2977	12/18639	0.333333333333333	2.08700033590863	0.110737186398848	0.344905822027631
GO:0016803	ether hydrolase activity	4/2977	12/18639	0.333333333333333	2.08700033590863	0.110737186398848	0.344905822027631
GO:0016840	carbon-nitrogen lyase activity	4/2977	12/18639	0.333333333333333	2.08700033590863	0.110737186398848	0.344905822027631
GO:0017166	vinculin binding	4/2977	12/18639	0.333333333333333	2.08700033590863	0.110737186398848	0.344905822027631
GO:0031543	peptidyl-proline dioxygenase activity	4/2977	12/18639	0.333333333333333	2.08700033590863	0.110737186398848	0.344905822027631
GO:0035197	siRNA binding	4/2977	12/18639	0.333333333333333	2.08700033590863	0.110737186398848	0.344905822027631
GO:0035251	UDP-glucosyltransferase activity	4/2977	12/18639	0.333333333333333	2.08700033590863	0.110737186398848	0.344905822027631
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	4/2977	12/18639	0.333333333333333	2.08700033590863	0.110737186398848	0.344905822027631
GO:0141221	histone deacetylase activity, hydrolytic mechanism	4/2977	12/18639	0.333333333333333	2.08700033590863	0.110737186398848	0.344905822027631
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/2977	12/18639	0.333333333333333	2.08700033590863	0.110737186398848	0.344905822027631
GO:0051117	ATPase binding	18/2977	84/18639	0.214285714285714	1.34164307308412	0.113809341937373	0.353611994292033
GO:0005200	structural constituent of cytoskeleton	23/2977	112/18639	0.205357142857143	1.28574127837228	0.118318389718757	0.366729572016632
GO:0016018	cyclosporin A binding	5/2977	17/18639	0.294117647058824	1.84147088462526	0.121572193078391	0.373449322949828
GO:0032183	SUMO binding	5/2977	17/18639	0.294117647058824	1.84147088462526	0.121572193078391	0.373449322949828
GO:0048038	quinone binding	5/2977	17/18639	0.294117647058824	1.84147088462526	0.121572193078391	0.373449322949828
GO:0043175	RNA polymerase core enzyme binding	10/2977	42/18639	0.238095238095238	1.49071452564902	0.121948604283538	0.373449322949828
GO:0051879	Hsp90 protein binding	10/2977	42/18639	0.238095238095238	1.49071452564902	0.121948604283538	0.373449322949828
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	6/2977	22/18639	0.272727272727273	1.70754572937979	0.126063045589604	0.384206465913901
GO:0046972	histone H4K16 acetyltransferase activity	6/2977	22/18639	0.272727272727273	1.70754572937979	0.126063045589604	0.384206465913901
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	7/2977	27/18639	0.259259259259259	1.62322248348449	0.127206971760783	0.386769768901238
GO:0016798	hydrolase activity, acting on glycosyl bonds	26/2977	130/18639	0.2	1.25220020154518	0.128831761131483	0.390779474976018
GO:0019838	growth factor binding	27/2977	136/18639	0.198529411764706	1.24299284712205	0.131905131482902	0.399153679866505
GO:0050660	flavin adenine dinucleotide binding	18/2977	86/18639	0.209302325581395	1.31044207138449	0.134494880429275	0.406028279688378
GO:0048156	tau protein binding	10/2977	43/18639	0.232558139534884	1.45604674598277	0.137388246548735	0.413784884063055
GO:0002161	aminoacyl-tRNA editing activity	4/2977	13/18639	0.307692307692308	1.92646184853105	0.140633169839966	0.418621347052767
GO:0004535	poly(A)-specific ribonuclease activity	4/2977	13/18639	0.307692307692308	1.92646184853105	0.140633169839966	0.418621347052767
GO:0046974	histone H3K9 methyltransferase activity	4/2977	13/18639	0.307692307692308	1.92646184853105	0.140633169839966	0.418621347052767
GO:0046975	histone H3K36 methyltransferase activity	4/2977	13/18639	0.307692307692308	1.92646184853105	0.140633169839966	0.418621347052767
GO:0097157	pre-mRNA intronic binding	4/2977	13/18639	0.307692307692308	1.92646184853105	0.140633169839966	0.418621347052767
GO:0015485	cholesterol binding	12/2977	54/18639	0.222222222222222	1.39133355727242	0.142989802808257	0.424646460898009
GO:0017124	SH3 domain binding	23/2977	115/18639	0.2	1.25220020154518	0.146070905948077	0.432790132008572
GO:0008525	phosphatidylcholine transporter activity	5/2977	18/18639	0.277777777777778	1.73916694659053	0.147324792881691	0.434043388427987
GO:0035615	clathrin adaptor activity	5/2977	18/18639	0.277777777777778	1.73916694659053	0.147324792881691	0.434043388427987
GO:0051537	2 iron, 2 sulfur cluster binding	7/2977	28/18639	0.25	1.56525025193147	0.147513571321649	0.434043388427987
GO:0016763	pentosyltransferase activity	11/2977	49/18639	0.224489795918367	1.40553083846908	0.148364235651195	0.435542825118564
GO:0051219	phosphoprotein binding	19/2977	93/18639	0.204301075268817	1.27912923813755	0.150532239552876	0.440893738323447
GO:0019903	protein phosphatase binding	28/2977	144/18639	0.194444444444444	1.21741686261337	0.152119616198727	0.444523455116188
GO:0019902	phosphatase binding	36/2977	190/18639	0.189473684210526	1.18629492777964	0.152575415158505	0.444837454697286
GO:1901981	phosphatidylinositol phosphate binding	35/2977	185/18639	0.189189189189189	1.18451370416436	0.158755547596093	0.461801444829639
GO:0016410	N-acyltransferase activity	19/2977	94/18639	0.202127659574468	1.26552148028502	0.161957262615312	0.470044146272168
GO:0015605	organophosphate ester transmembrane transporter activity	11/2977	50/18639	0.22	1.3774202216997	0.16436740708156	0.474015165286499
GO:0008376	acetylgalactosaminyltransferase activity	8/2977	34/18639	0.235294117647059	1.47317670770021	0.164439090228598	0.474015165286499
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	8/2977	34/18639	0.235294117647059	1.47317670770021	0.164439090228598	0.474015165286499
GO:0010484	histone H3 acetyltransferase activity	7/2977	29/18639	0.241379310344828	1.51127610531315	0.169233948480032	0.485644386986517
GO:0016417	S-acyltransferase activity	7/2977	29/18639	0.241379310344828	1.51127610531315	0.169233948480032	0.485644386986517
GO:0003735	structural constituent of ribosome	33/2977	175/18639	0.188571428571429	1.18064590431403	0.172004828106337	0.490680946331739
GO:0042625	ATPase-coupled ion transmembrane transporter activity	6/2977	24/18639	0.25	1.56525025193147	0.173115865022849	0.490680946331739
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	6/2977	24/18639	0.25	1.56525025193147	0.173115865022849	0.490680946331739
GO:0046961	proton-transporting ATPase activity, rotational mechanism	6/2977	24/18639	0.25	1.56525025193147	0.173115865022849	0.490680946331739
GO:0008174	mRNA methyltransferase activity	4/2977	14/18639	0.285714285714286	1.78885743077883	0.173294523724052	0.490680946331739
GO:0008494	translation activator activity	4/2977	14/18639	0.285714285714286	1.78885743077883	0.173294523724052	0.490680946331739
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	5/2977	19/18639	0.263157894736842	1.64763184413839	0.175150687677096	0.494839442839936
GO:0050997	quaternary ammonium group binding	9/2977	40/18639	0.225	1.40872522673833	0.178106435734862	0.499872348205316
GO:0061791	GTPase motor activity	9/2977	40/18639	0.225	1.40872522673833	0.178106435734862	0.499872348205316
GO:1990606	membrane scission GTPase motor activity	9/2977	40/18639	0.225	1.40872522673833	0.178106435734862	0.499872348205316
GO:0061631	ubiquitin conjugating enzyme activity	8/2977	35/18639	0.228571428571429	1.43108594462306	0.185193540506626	0.518623138655618
GO:0005548	phospholipid transporter activity	14/2977	68/18639	0.205882352941176	1.28902961923768	0.188086934219156	0.524425796938563
GO:0140223	general transcription initiation factor activity	14/2977	68/18639	0.205882352941176	1.28902961923768	0.188086934219156	0.524425796938563
GO:0030276	clathrin binding	10/2977	46/18639	0.217391304347826	1.36108717559259	0.189354206087528	0.526709974936872
GO:0015932	nucleobase-containing compound transmembrane transporter activity	12/2977	57/18639	0.210526315789474	1.31810547531072	0.189731079460424	0.526709974936872
GO:0005096	GTPase activator activity	49/2977	271/18639	0.180811808118081	1.13206291283605	0.190531652582152	0.526830584320331
GO:0015215	nucleotide transmembrane transporter activity	7/2977	30/18639	0.233333333333333	1.46090023513604	0.192249845178758	0.526830584320331
GO:0043995	histone H4K5 acetyltransferase activity	7/2977	30/18639	0.233333333333333	1.46090023513604	0.192249845178758	0.526830584320331
GO:0043996	histone H4K8 acetyltransferase activity	7/2977	30/18639	0.233333333333333	1.46090023513604	0.192249845178758	0.526830584320331
GO:0043997	histone H4K12 acetyltransferase activity	7/2977	30/18639	0.233333333333333	1.46090023513604	0.192249845178758	0.526830584320331
GO:0051721	protein phosphatase 2A binding	7/2977	30/18639	0.233333333333333	1.46090023513604	0.192249845178758	0.526830584320331
GO:0072341	modified amino acid binding	18/2977	91/18639	0.197802197802198	1.23843975976996	0.194837352016016	0.531468359790452
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	9/2977	41/18639	0.219512195121951	1.37436607486666	0.197960379872308	0.531468359790452
GO:0017080	sodium channel regulator activity	9/2977	41/18639	0.219512195121951	1.37436607486666	0.197960379872308	0.531468359790452
GO:0061650	ubiquitin-like protein conjugating enzyme activity	9/2977	41/18639	0.219512195121951	1.37436607486666	0.197960379872308	0.531468359790452
GO:0035091	phosphatidylinositol binding	51/2977	284/18639	0.179577464788732	1.12433468800712	0.19921621385887	0.531468359790452
GO:0016279	protein-lysine N-methyltransferase activity	14/2977	69/18639	0.202898550724638	1.27034803055308	0.2034701137013	0.531468359790452
GO:0016209	antioxidant activity	17/2977	86/18639	0.197674418604651	1.23763973408535	0.204085134671674	0.531468359790452
GO:0015095	magnesium ion transmembrane transporter activity	5/2977	20/18639	0.25	1.56525025193147	0.204771068749102	0.531468359790452
GO:0031418	L-ascorbic acid binding	5/2977	20/18639	0.25	1.56525025193147	0.204771068749102	0.531468359790452
GO:0000182	rDNA binding	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0003680	minor groove of adenine-thymine-rich DNA binding	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0005345	purine nucleobase transmembrane transporter activity	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0005528	FK506 binding	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0008190	eukaryotic initiation factor 4E binding	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0015187	glycine transmembrane transporter activity	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0030957	Tat protein binding	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0031996	thioesterase binding	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0035374	chondroitin sulfate binding	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0042975	peroxisome proliferator activated receptor binding	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0043121	neurotrophin binding	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0043295	glutathione binding	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0043422	protein kinase B binding	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0045322	unmethylated CpG binding	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0097177	mitochondrial ribosome binding	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0099122	RNA polymerase II C-terminal domain binding	3/2977	10/18639	0.3	1.87830030231777	0.205595434406017	0.531468359790452
GO:0008242	omega peptidase activity	4/2977	15/18639	0.266666666666667	1.66960026872691	0.208228103486892	0.532880336979481
GO:0015556	C4-dicarboxylate transmembrane transporter activity	4/2977	15/18639	0.266666666666667	1.66960026872691	0.208228103486892	0.532880336979481
GO:0055105	ubiquitin-protein transferase inhibitor activity	4/2977	15/18639	0.266666666666667	1.66960026872691	0.208228103486892	0.532880336979481
GO:0141050	histone H3K deacetylase activity	4/2977	15/18639	0.266666666666667	1.66960026872691	0.208228103486892	0.532880336979481
GO:0141051	histone H4K deacetylase activity	4/2977	15/18639	0.266666666666667	1.66960026872691	0.208228103486892	0.532880336979481
GO:0016758	hexosyltransferase activity	36/2977	197/18639	0.182741116751269	1.14414231613265	0.212632632653051	0.543063743795893
GO:0001618	virus receptor activity	16/2977	81/18639	0.197530864197531	1.23674093979771	0.213952988005191	0.545345240883491
GO:0070325	lipoprotein particle receptor binding	7/2977	31/18639	0.225806451612903	1.4137744210994	0.216428039095101	0.550554991881363
GO:0016278	lysine N-methyltransferase activity	14/2977	70/18639	0.2	1.25220020154518	0.21940007415044	0.555900584702604
GO:0097110	scaffold protein binding	14/2977	70/18639	0.2	1.25220020154518	0.21940007415044	0.555900584702604
GO:0015216	purine nucleotide transmembrane transporter activity	6/2977	26/18639	0.230769230769231	1.44484638639828	0.226149528220932	0.567373177874519
GO:0034237	protein kinase A regulatory subunit binding	6/2977	26/18639	0.230769230769231	1.44484638639828	0.226149528220932	0.567373177874519
GO:0050750	low-density lipoprotein particle receptor binding	6/2977	26/18639	0.230769230769231	1.44484638639828	0.226149528220932	0.567373177874519
GO:0052742	phosphatidylinositol kinase activity	6/2977	26/18639	0.230769230769231	1.44484638639828	0.226149528220932	0.567373177874519
GO:0097602	cullin family protein binding	6/2977	26/18639	0.230769230769231	1.44484638639828	0.226149528220932	0.567373177874519
GO:0140272	exogenous protein binding	16/2977	82/18639	0.195121951219512	1.22165873321481	0.228982941098721	0.573355325064837
GO:0019213	deacetylase activity	8/2977	37/18639	0.216216216216216	1.35372994761641	0.229742335351354	0.574131041572759
GO:0019208	phosphatase regulator activity	22/2977	117/18639	0.188034188034188	1.17728224076897	0.2338811930023	0.583332584890503
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	5/2977	21/18639	0.238095238095238	1.49071452564902	0.235886468517731	0.586044786570315
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	5/2977	21/18639	0.238095238095238	1.49071452564902	0.235886468517731	0.586044786570315
GO:0008378	galactosyltransferase activity	7/2977	32/18639	0.21875	1.36959397044004	0.241623775316891	0.59913312831004
GO:0004857	enzyme inhibitor activity	72/2977	416/18639	0.173076923076923	1.08363478979871	0.244393378672401	0.601777056035719
GO:0016722	oxidoreductase activity, acting on metal ions	4/2977	16/18639	0.25	1.56525025193147	0.24492439972214	0.601777056035719
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/2977	16/18639	0.25	1.56525025193147	0.24492439972214	0.601777056035719
GO:0097027	ubiquitin-protein transferase activator activity	4/2977	16/18639	0.25	1.56525025193147	0.24492439972214	0.601777056035719
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	24/2977	130/18639	0.184615384615385	1.15587710911863	0.250586874521829	0.601777056035719
GO:0002162	dystroglycan binding	3/2977	11/18639	0.272727272727273	1.70754572937979	0.251172412581862	0.601777056035719
GO:0008199	ferric iron binding	3/2977	11/18639	0.272727272727273	1.70754572937979	0.251172412581862	0.601777056035719
GO:0008526	phosphatidylinositol transfer activity	3/2977	11/18639	0.272727272727273	1.70754572937979	0.251172412581862	0.601777056035719
GO:0015205	nucleobase transmembrane transporter activity	3/2977	11/18639	0.272727272727273	1.70754572937979	0.251172412581862	0.601777056035719
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	3/2977	11/18639	0.272727272727273	1.70754572937979	0.251172412581862	0.601777056035719
GO:0019107	myristoyltransferase activity	3/2977	11/18639	0.272727272727273	1.70754572937979	0.251172412581862	0.601777056035719
GO:0032050	clathrin heavy chain binding	3/2977	11/18639	0.272727272727273	1.70754572937979	0.251172412581862	0.601777056035719
GO:0034713	type I transforming growth factor beta receptor binding	3/2977	11/18639	0.272727272727273	1.70754572937979	0.251172412581862	0.601777056035719
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	3/2977	11/18639	0.272727272727273	1.70754572937979	0.251172412581862	0.601777056035719
GO:0045294	alpha-catenin binding	3/2977	11/18639	0.272727272727273	1.70754572937979	0.251172412581862	0.601777056035719
GO:0140537	transcription regulator activator activity	3/2977	11/18639	0.272727272727273	1.70754572937979	0.251172412581862	0.601777056035719
GO:1900750	oligopeptide binding	3/2977	11/18639	0.272727272727273	1.70754572937979	0.251172412581862	0.601777056035719
GO:1990948	ubiquitin ligase inhibitor activity	3/2977	11/18639	0.272727272727273	1.70754572937979	0.251172412581862	0.601777056035719
GO:0044325	transmembrane transporter binding	25/2977	136/18639	0.183823529411765	1.15091930289079	0.252167501705662	0.602769658618111
GO:0005518	collagen binding	14/2977	72/18639	0.194444444444444	1.21741686261337	0.252756477222797	0.602769658618111
GO:0042887	amide transmembrane transporter activity	8/2977	38/18639	0.210526315789474	1.31810547531072	0.253318197534171	0.602769658618111
GO:0001671	ATPase activator activity	6/2977	27/18639	0.222222222222222	1.39133355727242	0.254418830066689	0.602769658618111
GO:0004364	glutathione transferase activity	6/2977	27/18639	0.222222222222222	1.39133355727242	0.254418830066689	0.602769658618111
GO:0005385	zinc ion transmembrane transporter activity	6/2977	27/18639	0.222222222222222	1.39133355727242	0.254418830066689	0.602769658618111
GO:0140311	protein sequestering activity	7/2977	33/18639	0.212121212121212	1.32809112285095	0.267684156384406	0.617072803439057
GO:0008093	cytoskeletal anchor activity	5/2977	22/18639	0.227272727272727	1.42295477448316	0.268187475261297	0.617072803439057
GO:0032931	histone H3K56 acetyltransferase activity	5/2977	22/18639	0.227272727272727	1.42295477448316	0.268187475261297	0.617072803439057
GO:0043992	histone H3K9 acetyltransferase activity	5/2977	22/18639	0.227272727272727	1.42295477448316	0.268187475261297	0.617072803439057
GO:0043993	histone H3K18 acetyltransferase activity	5/2977	22/18639	0.227272727272727	1.42295477448316	0.268187475261297	0.617072803439057
GO:0043994	histone H3K23 acetyltransferase activity	5/2977	22/18639	0.227272727272727	1.42295477448316	0.268187475261297	0.617072803439057
GO:0043999	histone H2AK5 acetyltransferase activity	5/2977	22/18639	0.227272727272727	1.42295477448316	0.268187475261297	0.617072803439057
GO:0044012	histone H2AK9 acetyltransferase activity	5/2977	22/18639	0.227272727272727	1.42295477448316	0.268187475261297	0.617072803439057
GO:0044014	histone H2BK5 acetyltransferase activity	5/2977	22/18639	0.227272727272727	1.42295477448316	0.268187475261297	0.617072803439057
GO:0044015	histone H2BK12 acetyltransferase activity	5/2977	22/18639	0.227272727272727	1.42295477448316	0.268187475261297	0.617072803439057
GO:0044016	histone H3K4 acetyltransferase activity	5/2977	22/18639	0.227272727272727	1.42295477448316	0.268187475261297	0.617072803439057
GO:0044017	histone H3K27 acetyltransferase activity	5/2977	22/18639	0.227272727272727	1.42295477448316	0.268187475261297	0.617072803439057
GO:0044018	histone H3K36 acetyltransferase activity	5/2977	22/18639	0.227272727272727	1.42295477448316	0.268187475261297	0.617072803439057
GO:0050321	tau-protein kinase activity	5/2977	22/18639	0.227272727272727	1.42295477448316	0.268187475261297	0.617072803439057
GO:0061133	endopeptidase activator activity	5/2977	22/18639	0.227272727272727	1.42295477448316	0.268187475261297	0.617072803439057
GO:0140908	histone H3K122 acetyltransferase activity	5/2977	22/18639	0.227272727272727	1.42295477448316	0.268187475261297	0.617072803439057
GO:0019212	phosphatase inhibitor activity	11/2977	56/18639	0.196428571428571	1.22983948366044	0.275596070288139	0.631842337087887
GO:0030170	pyridoxal phosphate binding	11/2977	56/18639	0.196428571428571	1.22983948366044	0.275596070288139	0.631842337087887
GO:0016776	phosphotransferase activity, phosphate group as acceptor	8/2977	39/18639	0.205128205128205	1.2843078990207	0.27760485459976	0.635307167247121
GO:0004029	aldehyde dehydrogenase (NAD+) activity	4/2977	17/18639	0.235294117647059	1.47317670770021	0.282878924843294	0.639356437212188
GO:0004550	nucleoside diphosphate kinase activity	4/2977	17/18639	0.235294117647059	1.47317670770021	0.282878924843294	0.639356437212188
GO:0004659	prenyltransferase activity	4/2977	17/18639	0.235294117647059	1.47317670770021	0.282878924843294	0.639356437212188
GO:0008429	phosphatidylethanolamine binding	4/2977	17/18639	0.235294117647059	1.47317670770021	0.282878924843294	0.639356437212188
GO:0016805	dipeptidase activity	4/2977	17/18639	0.235294117647059	1.47317670770021	0.282878924843294	0.639356437212188
GO:0070403	NAD+ binding	4/2977	17/18639	0.235294117647059	1.47317670770021	0.282878924843294	0.639356437212188
GO:1990226	histone methyltransferase binding	4/2977	17/18639	0.235294117647059	1.47317670770021	0.282878924843294	0.639356437212188
GO:0036408	histone H3K14 acetyltransferase activity	6/2977	28/18639	0.214285714285714	1.34164307308412	0.283574809724427	0.639796876357055
GO:0032934	sterol binding	13/2977	68/18639	0.191176470588235	1.19695607500642	0.284470546284913	0.640685868793359
GO:0005048	signal sequence binding	10/2977	51/18639	0.196078431372549	1.22764725641684	0.29129039528656	0.653739604184423
GO:0030544	Hsp70 protein binding	10/2977	51/18639	0.196078431372549	1.22764725641684	0.29129039528656	0.653739604184423
GO:0070279	vitamin B6 binding	11/2977	57/18639	0.192982456140351	1.20826335236816	0.296129002877375	0.658349075223082
GO:0042626	ATPase-coupled transmembrane transporter activity	18/2977	98/18639	0.183673469387755	1.14997977692925	0.296855095593985	0.658349075223082
GO:0005527	macrolide binding	3/2977	12/18639	0.25	1.56525025193147	0.297984154642867	0.658349075223082
GO:0015132	prostaglandin transmembrane transporter activity	3/2977	12/18639	0.25	1.56525025193147	0.297984154642867	0.658349075223082
GO:0016273	arginine N-methyltransferase activity	3/2977	12/18639	0.25	1.56525025193147	0.297984154642867	0.658349075223082
GO:0016274	protein-arginine N-methyltransferase activity	3/2977	12/18639	0.25	1.56525025193147	0.297984154642867	0.658349075223082
GO:0045295	gamma-catenin binding	3/2977	12/18639	0.25	1.56525025193147	0.297984154642867	0.658349075223082
GO:0070410	co-SMAD binding	3/2977	12/18639	0.25	1.56525025193147	0.297984154642867	0.658349075223082
GO:0097371	MDM2/MDM4 family protein binding	3/2977	12/18639	0.25	1.56525025193147	0.297984154642867	0.658349075223082
GO:1901682	sulfur compound transmembrane transporter activity	12/2977	63/18639	0.19047619047619	1.19257162051922	0.300056851232011	0.658975935237028
GO:0000295	adenine nucleotide transmembrane transporter activity	5/2977	23/18639	0.217391304347826	1.36108717559259	0.301364092543794	0.658975935237028
GO:0004602	glutathione peroxidase activity	5/2977	23/18639	0.217391304347826	1.36108717559259	0.301364092543794	0.658975935237028
GO:0005158	insulin receptor binding	5/2977	23/18639	0.217391304347826	1.36108717559259	0.301364092543794	0.658975935237028
GO:0031681	G-protein beta-subunit binding	5/2977	23/18639	0.217391304347826	1.36108717559259	0.301364092543794	0.658975935237028
GO:0044013	histone H2B acetyltransferase activity	5/2977	23/18639	0.217391304347826	1.36108717559259	0.301364092543794	0.658975935237028
GO:0004177	aminopeptidase activity	8/2977	40/18639	0.2	1.25220020154518	0.302479459315985	0.660011667398875
GO:0051087	protein-folding chaperone binding	24/2977	134/18639	0.17910447761194	1.12137331481658	0.302871446433626	0.660011667398875
GO:0005080	protein kinase C binding	10/2977	52/18639	0.192307692307692	1.2040386553319	0.313322539245542	0.679482941999757
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	6/2977	29/18639	0.206896551724138	1.29537951883984	0.313402860483834	0.679482941999757
GO:0097472	cyclin-dependent protein kinase activity	6/2977	29/18639	0.206896551724138	1.29537951883984	0.313402860483834	0.679482941999757
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	4/2977	18/18639	0.222222222222222	1.39133355727242	0.321608676832323	0.691404512314607
GO:0008308	voltage-gated monoatomic anion channel activity	4/2977	18/18639	0.222222222222222	1.39133355727242	0.321608676832323	0.691404512314607
GO:0070064	proline-rich region binding	4/2977	18/18639	0.222222222222222	1.39133355727242	0.321608676832323	0.691404512314607
GO:1901611	phosphatidylglycerol binding	4/2977	18/18639	0.222222222222222	1.39133355727242	0.321608676832323	0.691404512314607
GO:1990381	ubiquitin-specific protease binding	4/2977	18/18639	0.222222222222222	1.39133355727242	0.321608676832323	0.691404512314607
GO:0016651	oxidoreductase activity, acting on NAD(P)H	16/2977	88/18639	0.181818181818182	1.13836381958653	0.327056983250353	0.701935743883531
GO:0002020	protease binding	24/2977	136/18639	0.176470588235294	1.10488253077516	0.330254889512098	0.70760988910562
GO:0005540	hyaluronic acid binding	5/2977	24/18639	0.208333333333333	1.3043752099429	0.335113626101937	0.715618897210993
GO:0035035	histone acetyltransferase binding	5/2977	24/18639	0.208333333333333	1.3043752099429	0.335113626101937	0.715618897210993
GO:0004864	protein phosphatase inhibitor activity	10/2977	53/18639	0.188679245283019	1.18132094485394	0.335713017973792	0.715702043326431
GO:0031593	polyubiquitin modification-dependent protein binding	11/2977	59/18639	0.186440677966102	1.16730527262686	0.33830621940144	0.71909776143056
GO:0001965	G-protein alpha-subunit binding	6/2977	30/18639	0.2	1.25220020154518	0.343691114310103	0.71909776143056
GO:0031210	phosphatidylcholine binding	6/2977	30/18639	0.2	1.25220020154518	0.343691114310103	0.71909776143056
GO:0019888	protein phosphatase regulator activity	19/2977	107/18639	0.177570093457944	1.11176653408217	0.345140793527924	0.71909776143056
GO:0003964	RNA-directed DNA polymerase activity	3/2977	13/18639	0.230769230769231	1.44484638639828	0.345189450083738	0.71909776143056
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/2977	13/18639	0.230769230769231	1.44484638639828	0.345189450083738	0.71909776143056
GO:0005172	vascular endothelial growth factor receptor binding	3/2977	13/18639	0.230769230769231	1.44484638639828	0.345189450083738	0.71909776143056
GO:0008035	high-density lipoprotein particle binding	3/2977	13/18639	0.230769230769231	1.44484638639828	0.345189450083738	0.71909776143056
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3/2977	13/18639	0.230769230769231	1.44484638639828	0.345189450083738	0.71909776143056
GO:0030955	potassium ion binding	3/2977	13/18639	0.230769230769231	1.44484638639828	0.345189450083738	0.71909776143056
GO:0035673	oligopeptide transmembrane transporter activity	3/2977	13/18639	0.230769230769231	1.44484638639828	0.345189450083738	0.71909776143056
GO:0071714	icosanoid transmembrane transporter activity	3/2977	13/18639	0.230769230769231	1.44484638639828	0.345189450083738	0.71909776143056
GO:0071837	HMG box domain binding	3/2977	13/18639	0.230769230769231	1.44484638639828	0.345189450083738	0.71909776143056
GO:0140333	glycerophospholipid flippase activity	3/2977	13/18639	0.230769230769231	1.44484638639828	0.345189450083738	0.71909776143056
GO:0019894	kinesin binding	8/2977	42/18639	0.19047619047619	1.19257162051922	0.35349425416787	0.735198961844251
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	10/2977	54/18639	0.185185185185185	1.15944463106035	0.358377920961128	0.736908972088327
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	11/2977	60/18639	0.183333333333333	1.14785018474975	0.35980874048005	0.736908972088327
GO:0005346	purine ribonucleotide transmembrane transporter activity	4/2977	19/18639	0.210526315789474	1.31810547531072	0.360664140607051	0.736908972088327
GO:0005520	insulin-like growth factor binding	4/2977	19/18639	0.210526315789474	1.31810547531072	0.360664140607051	0.736908972088327
GO:0008381	mechanosensitive monoatomic ion channel activity	4/2977	19/18639	0.210526315789474	1.31810547531072	0.360664140607051	0.736908972088327
GO:0015245	fatty acid transmembrane transporter activity	4/2977	19/18639	0.210526315789474	1.31810547531072	0.360664140607051	0.736908972088327
GO:0030506	ankyrin binding	4/2977	19/18639	0.210526315789474	1.31810547531072	0.360664140607051	0.736908972088327
GO:0031420	alkali metal ion binding	4/2977	19/18639	0.210526315789474	1.31810547531072	0.360664140607051	0.736908972088327
GO:0042800	histone H3K4 methyltransferase activity	4/2977	19/18639	0.210526315789474	1.31810547531072	0.360664140607051	0.736908972088327
GO:0046624	sphingolipid transporter activity	4/2977	19/18639	0.210526315789474	1.31810547531072	0.360664140607051	0.736908972088327
GO:0050145	nucleoside monophosphate kinase activity	4/2977	19/18639	0.210526315789474	1.31810547531072	0.360664140607051	0.736908972088327
GO:0022804	active transmembrane transporter activity	76/2977	457/18639	0.166301969365427	1.04121679778374	0.368168682867015	0.751040587893255
GO:0017025	TBP-class protein binding	5/2977	25/18639	0.2	1.25220020154518	0.369147079990739	0.751835440427709
GO:0016791	phosphatase activity	46/2977	273/18639	0.168498168498169	1.054967202767	0.369920487400272	0.752210927404693
GO:0005310	dicarboxylic acid transmembrane transporter activity	6/2977	31/18639	0.193548387096774	1.21180664665663	0.374234252361704	0.758566889310945
GO:0008327	methyl-CpG binding	6/2977	31/18639	0.193548387096774	1.21180664665663	0.374234252361704	0.758566889310945
GO:0046906	tetrapyrrole binding	26/2977	152/18639	0.171052631578947	1.07096069868996	0.384126257719825	0.777383884482118
GO:0005347	ATP transmembrane transporter activity	3/2977	14/18639	0.214285714285714	1.34164307308412	0.39206988454547	0.782301941507134
GO:0008559	ABC-type xenobiotic transporter activity	3/2977	14/18639	0.214285714285714	1.34164307308412	0.39206988454547	0.782301941507134
GO:0015926	glucosidase activity	3/2977	14/18639	0.214285714285714	1.34164307308412	0.39206988454547	0.782301941507134
GO:0016530	metallochaperone activity	3/2977	14/18639	0.214285714285714	1.34164307308412	0.39206988454547	0.782301941507134
GO:0032454	histone H3K9 demethylase activity	3/2977	14/18639	0.214285714285714	1.34164307308412	0.39206988454547	0.782301941507134
GO:0042813	Wnt receptor activity	3/2977	14/18639	0.214285714285714	1.34164307308412	0.39206988454547	0.782301941507134
GO:0070742	C2H2 zinc finger domain binding	3/2977	14/18639	0.214285714285714	1.34164307308412	0.39206988454547	0.782301941507134
GO:0071933	Arp2/3 complex binding	3/2977	14/18639	0.214285714285714	1.34164307308412	0.39206988454547	0.782301941507134
GO:1901612	cardiolipin binding	3/2977	14/18639	0.214285714285714	1.34164307308412	0.39206988454547	0.782301941507134
GO:0004222	metalloendopeptidase activity	19/2977	110/18639	0.172727272727273	1.0814456286072	0.393426060849562	0.783783275670657
GO:0030742	GTP-dependent protein binding	4/2977	20/18639	0.2	1.25220020154518	0.399637408571538	0.792448712338283
GO:0052745	inositol phosphate phosphatase activity	4/2977	20/18639	0.2	1.25220020154518	0.399637408571538	0.792448712338283
GO:0140939	histone H4 methyltransferase activity	4/2977	20/18639	0.2	1.25220020154518	0.399637408571538	0.792448712338283
GO:0005160	transforming growth factor beta receptor binding	5/2977	26/18639	0.192307692307692	1.2040386553319	0.403194116126408	0.795794260113482
GO:0030507	spectrin binding	5/2977	26/18639	0.192307692307692	1.2040386553319	0.403194116126408	0.795794260113482
GO:0070006	metalloaminopeptidase activity	5/2977	26/18639	0.192307692307692	1.2040386553319	0.403194116126408	0.795794260113482
GO:0031369	translation initiation factor binding	6/2977	32/18639	0.1875	1.17393768894861	0.404836670141277	0.797803129275324
GO:0051213	dioxygenase activity	16/2977	93/18639	0.172043010752688	1.07716146369478	0.415236600243581	0.817037193391452
GO:0140789	histone phosphatase activity	23/2977	136/18639	0.169117647058824	1.05884575865953	0.417558779630677	0.820342402443653
GO:0015101	organic cation transmembrane transporter activity	14/2977	81/18639	0.172839506172839	1.08214832232299	0.419090099248791	0.82208610866468
GO:0016504	peptidase activator activity	10/2977	57/18639	0.175438596491228	1.0984212294256	0.427192041643306	0.83669361530445
GO:0016830	carbon-carbon lyase activity	9/2977	51/18639	0.176470588235294	1.10488253077516	0.429273377735879	0.837633700640575
GO:0046915	transition metal ion transmembrane transporter activity	8/2977	45/18639	0.177777777777778	1.11306684581794	0.431349397966443	0.837633700640575
GO:0140303	intramembrane lipid transporter activity	8/2977	45/18639	0.177777777777778	1.11306684581794	0.431349397966443	0.837633700640575
GO:0071889	14-3-3 protein binding	6/2977	33/18639	0.181818181818182	1.13836381958653	0.435315006531692	0.837633700640575
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	5/2977	27/18639	0.185185185185185	1.15944463106035	0.43700668113998	0.837633700640575
GO:0005041	low-density lipoprotein particle receptor activity	3/2977	15/18639	0.2	1.25220020154518	0.438030329810114	0.837633700640575
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	3/2977	15/18639	0.2	1.25220020154518	0.438030329810114	0.837633700640575
GO:0016846	carbon-sulfur lyase activity	3/2977	15/18639	0.2	1.25220020154518	0.438030329810114	0.837633700640575
GO:0033130	acetylcholine receptor binding	3/2977	15/18639	0.2	1.25220020154518	0.438030329810114	0.837633700640575
GO:0048531	beta-1,3-galactosyltransferase activity	3/2977	15/18639	0.2	1.25220020154518	0.438030329810114	0.837633700640575
GO:0050780	dopamine receptor binding	3/2977	15/18639	0.2	1.25220020154518	0.438030329810114	0.837633700640575
GO:0051371	muscle alpha-actinin binding	3/2977	15/18639	0.2	1.25220020154518	0.438030329810114	0.837633700640575
GO:0120283	protein serine/threonine kinase binding	3/2977	15/18639	0.2	1.25220020154518	0.438030329810114	0.837633700640575
GO:0010314	phosphatidylinositol-5-phosphate binding	4/2977	21/18639	0.19047619047619	1.19257162051922	0.438167041525375	0.837633700640575
GO:0019200	carbohydrate kinase activity	4/2977	21/18639	0.19047619047619	1.19257162051922	0.438167041525375	0.837633700640575
GO:0035613	RNA stem-loop binding	4/2977	21/18639	0.19047619047619	1.19257162051922	0.438167041525375	0.837633700640575
GO:0031406	carboxylic acid binding	31/2977	187/18639	0.165775401069519	1.03791995315242	0.440843355482879	0.841490231616797
GO:0004721	phosphoprotein phosphatase activity	29/2977	175/18639	0.165714285714286	1.03753730985172	0.445660788822763	0.849416160189057
GO:0071949	FAD binding	7/2977	40/18639	0.175	1.09567517635203	0.461153093318472	0.877634128416824
GO:0008238	exopeptidase activity	17/2977	102/18639	0.166666666666667	1.04350016795432	0.465330124435465	0.88196377486722
GO:0016831	carboxy-lyase activity	6/2977	34/18639	0.176470588235294	1.10488253077516	0.465500065983169	0.88196377486722
GO:0019825	oxygen binding	6/2977	34/18639	0.176470588235294	1.10488253077516	0.465500065983169	0.88196377486722
GO:0043177	organic acid binding	31/2977	189/18639	0.164021164021164	1.02693667322488	0.466280247335926	0.882133149404412
GO:0051393	alpha-actinin binding	5/2977	28/18639	0.178571428571429	1.11803589423677	0.470361435795535	0.888537801051624
GO:0045309	protein phosphorylated amino acid binding	10/2977	59/18639	0.169491525423729	1.06118661147897	0.472959688104027	0.890810503995342
GO:0070888	E-box binding	10/2977	59/18639	0.169491525423729	1.06118661147897	0.472959688104027	0.890810503995342
GO:0030695	GTPase regulator activity	79/2977	489/18639	0.161554192229039	1.01149096034836	0.474828405125168	0.893013068254551
GO:1901505	carbohydrate derivative transmembrane transporter activity	9/2977	53/18639	0.169811320754717	1.06318885036855	0.477643572866861	0.893157043849336
GO:0008237	metallopeptidase activity	30/2977	184/18639	0.16304347826087	1.02081538169444	0.481992887278042	0.893157043849336
GO:0005159	insulin-like growth factor receptor binding	3/2977	16/18639	0.1875	1.17393768894861	0.482593236753493	0.893157043849336
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/2977	16/18639	0.1875	1.17393768894861	0.482593236753493	0.893157043849336
GO:0008142	oxysterol binding	3/2977	16/18639	0.1875	1.17393768894861	0.482593236753493	0.893157043849336
GO:0022858	alanine transmembrane transporter activity	3/2977	16/18639	0.1875	1.17393768894861	0.482593236753493	0.893157043849336
GO:0140327	flippase activity	3/2977	16/18639	0.1875	1.17393768894861	0.482593236753493	0.893157043849336
GO:0060589	nucleoside-triphosphatase regulator activity	79/2977	490/18639	0.161224489795918	1.00942669308234	0.482794042614494	0.893157043849336
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	20/2977	122/18639	0.163934426229508	1.02639360782392	0.487439636199038	0.893157043849336
GO:0015175	neutral L-amino acid transmembrane transporter activity	7/2977	41/18639	0.170731707317073	1.06895139156296	0.488604555890422	0.893157043849336
GO:0008235	metalloexopeptidase activity	11/2977	66/18639	0.166666666666667	1.04350016795432	0.490236065856949	0.893157043849336
GO:0005337	nucleoside transmembrane transporter activity	2/2977	10/18639	0.2	1.25220020154518	0.490991577746463	0.893157043849336
GO:0005381	iron ion transmembrane transporter activity	2/2977	10/18639	0.2	1.25220020154518	0.490991577746463	0.893157043849336
GO:0005522	profilin binding	2/2977	10/18639	0.2	1.25220020154518	0.490991577746463	0.893157043849336
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/2977	10/18639	0.2	1.25220020154518	0.490991577746463	0.893157043849336
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/2977	10/18639	0.2	1.25220020154518	0.490991577746463	0.893157043849336
GO:0016868	intramolecular phosphotransferase activity	2/2977	10/18639	0.2	1.25220020154518	0.490991577746463	0.893157043849336
GO:0032052	bile acid binding	2/2977	10/18639	0.2	1.25220020154518	0.490991577746463	0.893157043849336
GO:0140135	mechanosensitive monoatomic cation channel activity	2/2977	10/18639	0.2	1.25220020154518	0.490991577746463	0.893157043849336
GO:0140940	histone H2A methyltransferase activity	2/2977	10/18639	0.2	1.25220020154518	0.490991577746463	0.893157043849336
GO:0140999	histone H3K4 trimethyltransferase activity	2/2977	10/18639	0.2	1.25220020154518	0.490991577746463	0.893157043849336
GO:1990259	histone H2AQ104 methyltransferase activity	2/2977	10/18639	0.2	1.25220020154518	0.490991577746463	0.893157043849336
GO:1990757	ubiquitin ligase activator activity	2/2977	10/18639	0.2	1.25220020154518	0.490991577746463	0.893157043849336
GO:0003785	actin monomer binding	5/2977	29/18639	0.172413793103448	1.07948293236653	0.503061138985472	0.908640840854948
GO:0035250	UDP-galactosyltransferase activity	5/2977	29/18639	0.172413793103448	1.07948293236653	0.503061138985472	0.908640840854948
GO:0043236	laminin binding	5/2977	29/18639	0.172413793103448	1.07948293236653	0.503061138985472	0.908640840854948
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	5/2977	29/18639	0.172413793103448	1.07948293236653	0.503061138985472	0.908640840854948
GO:0051861	glycolipid binding	5/2977	29/18639	0.172413793103448	1.07948293236653	0.503061138985472	0.908640840854948
GO:0032266	phosphatidylinositol-3-phosphate binding	8/2977	48/18639	0.166666666666667	1.04350016795432	0.50810411141214	0.91645331959506
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	11/2977	67/18639	0.164179104477612	1.02792553858186	0.511602448410522	0.921461673653367
GO:0005201	extracellular matrix structural constituent	27/2977	168/18639	0.160714285714286	1.00623230481309	0.518645937487029	0.932832200240755
GO:0042578	phosphoric ester hydrolase activity	58/2977	363/18639	0.159779614325069	1.00038032630331	0.521287204830463	0.936264079561886
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	3/2977	17/18639	0.176470588235294	1.10488253077516	0.525389160734251	0.937041841141953
GO:0005092	GDP-dissociation inhibitor activity	3/2977	17/18639	0.176470588235294	1.10488253077516	0.525389160734251	0.937041841141953
GO:0030169	low-density lipoprotein particle binding	3/2977	17/18639	0.176470588235294	1.10488253077516	0.525389160734251	0.937041841141953
GO:0032977	membrane insertase activity	3/2977	17/18639	0.176470588235294	1.10488253077516	0.525389160734251	0.937041841141953
GO:0036041	long-chain fatty acid binding	3/2977	17/18639	0.176470588235294	1.10488253077516	0.525389160734251	0.937041841141953
GO:0031624	ubiquitin conjugating enzyme binding	5/2977	30/18639	0.166666666666667	1.04350016795432	0.534935143920546	0.946936777304042
GO:0004712	protein serine/threonine/tyrosine kinase activity	7/2977	43/18639	0.162790697674419	1.01923272218794	0.542117592907027	0.946936777304042
GO:0008200	ion channel inhibitor activity	7/2977	43/18639	0.162790697674419	1.01923272218794	0.542117592907027	0.946936777304042
GO:0000099	sulfur amino acid transmembrane transporter activity	2/2977	11/18639	0.181818181818182	1.13836381958653	0.54428472556082	0.946936777304042
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/2977	11/18639	0.181818181818182	1.13836381958653	0.54428472556082	0.946936777304042
GO:0003953	NAD+ nucleosidase activity	2/2977	11/18639	0.181818181818182	1.13836381958653	0.54428472556082	0.946936777304042
GO:0008271	secondary active sulfate transmembrane transporter activity	2/2977	11/18639	0.181818181818182	1.13836381958653	0.54428472556082	0.946936777304042
GO:0010854	adenylate cyclase regulator activity	2/2977	11/18639	0.181818181818182	1.13836381958653	0.54428472556082	0.946936777304042
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	2/2977	11/18639	0.181818181818182	1.13836381958653	0.54428472556082	0.946936777304042
GO:0015173	aromatic amino acid transmembrane transporter activity	2/2977	11/18639	0.181818181818182	1.13836381958653	0.54428472556082	0.946936777304042
GO:0015217	ADP transmembrane transporter activity	2/2977	11/18639	0.181818181818182	1.13836381958653	0.54428472556082	0.946936777304042
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/2977	11/18639	0.181818181818182	1.13836381958653	0.54428472556082	0.946936777304042
GO:0035252	UDP-xylosyltransferase activity	2/2977	11/18639	0.181818181818182	1.13836381958653	0.54428472556082	0.946936777304042
GO:0042285	xylosyltransferase activity	2/2977	11/18639	0.181818181818182	1.13836381958653	0.54428472556082	0.946936777304042
GO:0050786	RAGE receptor binding	2/2977	11/18639	0.181818181818182	1.13836381958653	0.54428472556082	0.946936777304042
GO:0050998	nitric-oxide synthase binding	2/2977	11/18639	0.181818181818182	1.13836381958653	0.54428472556082	0.946936777304042
GO:0070697	activin receptor binding	2/2977	11/18639	0.181818181818182	1.13836381958653	0.54428472556082	0.946936777304042
GO:0140031	phosphorylation-dependent protein binding	2/2977	11/18639	0.181818181818182	1.13836381958653	0.54428472556082	0.946936777304042
GO:0061630	ubiquitin protein ligase activity	56/2977	353/18639	0.158640226628895	0.993246618789378	0.545122479721881	0.94710395456441
GO:0061659	ubiquitin-like protein ligase activity	59/2977	372/18639	0.158602150537634	0.993008224343624	0.545963492294209	0.947276331059381
GO:0004622	lysophospholipase activity	4/2977	24/18639	0.166666666666667	1.04350016795432	0.548209066445041	0.949881923813185
GO:0042805	actinin binding	6/2977	37/18639	0.162162162162162	1.01529746071231	0.552841145745119	0.95660995002238
GO:0140767	enzyme-substrate adaptor activity	22/2977	139/18639	0.158273381294964	0.990949799783955	0.55458143326795	0.958322720274928
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	13/2977	82/18639	0.158536585365854	0.992597720737033	0.558327067572143	0.960688601488517
GO:0033218	amide binding	39/2977	247/18639	0.157894736842105	0.988579106483037	0.558530672258601	0.960688601488517
GO:0005507	copper ion binding	10/2977	63/18639	0.158730158730159	0.993809683766016	0.561692095349322	0.960688601488517
GO:0005164	tumor necrosis factor receptor binding	5/2977	31/18639	0.161290322580645	1.00983887221385	0.565839161528016	0.960688601488517
GO:0016878	acid-thiol ligase activity	5/2977	31/18639	0.161290322580645	1.00983887221385	0.565839161528016	0.960688601488517
GO:0017147	Wnt-protein binding	5/2977	31/18639	0.161290322580645	1.00983887221385	0.565839161528016	0.960688601488517
GO:0000900	mRNA regulatory element binding translation repressor activity	3/2977	18/18639	0.166666666666667	1.04350016795432	0.566145257514636	0.960688601488517
GO:0015172	acidic amino acid transmembrane transporter activity	3/2977	18/18639	0.166666666666667	1.04350016795432	0.566145257514636	0.960688601488517
GO:0016854	racemase and epimerase activity	3/2977	18/18639	0.166666666666667	1.04350016795432	0.566145257514636	0.960688601488517
GO:0017128	phospholipid scramblase activity	3/2977	18/18639	0.166666666666667	1.04350016795432	0.566145257514636	0.960688601488517
GO:0030228	lipoprotein particle receptor activity	3/2977	18/18639	0.166666666666667	1.04350016795432	0.566145257514636	0.960688601488517
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	3/2977	18/18639	0.166666666666667	1.04350016795432	0.566145257514636	0.960688601488517
GO:0005319	lipid transporter activity	28/2977	178/18639	0.157303370786517	0.984876563013063	0.567042132002796	0.960688601488517
GO:0001223	transcription coactivator binding	7/2977	44/18639	0.159090909090909	0.996068342138211	0.567987387724221	0.960688601488517
GO:0016248	channel inhibitor activity	7/2977	44/18639	0.159090909090909	0.996068342138211	0.567987387724221	0.960688601488517
GO:0043014	alpha-tubulin binding	7/2977	44/18639	0.159090909090909	0.996068342138211	0.567987387724221	0.960688601488517
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	14/2977	89/18639	0.157303370786517	0.984876563013063	0.56964175131183	0.96094123702141
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	14/2977	89/18639	0.157303370786517	0.984876563013063	0.56964175131183	0.96094123702141
GO:0016782	transferase activity, transferring sulphur-containing groups	11/2977	70/18639	0.157142857142857	0.983871586928355	0.57392852828021	0.963096264744106
GO:0004709	MAP kinase kinase kinase activity	4/2977	25/18639	0.16	1.00176016123614	0.582316111483955	0.963096264744106
GO:0005537	D-mannose binding	4/2977	25/18639	0.16	1.00176016123614	0.582316111483955	0.963096264744106
GO:0008483	transaminase activity	4/2977	25/18639	0.16	1.00176016123614	0.582316111483955	0.963096264744106
GO:0015662	P-type ion transporter activity	4/2977	25/18639	0.16	1.00176016123614	0.582316111483955	0.963096264744106
GO:0019211	phosphatase activator activity	4/2977	25/18639	0.16	1.00176016123614	0.582316111483955	0.963096264744106
GO:0019706	protein-cysteine S-palmitoyltransferase activity	4/2977	25/18639	0.16	1.00176016123614	0.582316111483955	0.963096264744106
GO:0019707	protein-cysteine S-acyltransferase activity	4/2977	25/18639	0.16	1.00176016123614	0.582316111483955	0.963096264744106
GO:0140358	P-type transmembrane transporter activity	4/2977	25/18639	0.16	1.00176016123614	0.582316111483955	0.963096264744106
GO:0140793	histone H2AXY142 phosphatase activity	14/2977	90/18639	0.155555555555556	0.973933490090695	0.587517398785037	0.963096264744106
GO:0015297	antiporter activity	21/2977	135/18639	0.155555555555556	0.973933490090695	0.589101851376131	0.963096264744106
GO:0004715	non-membrane spanning protein tyrosine kinase activity	7/2977	45/18639	0.155555555555556	0.973933490090695	0.593157543732233	0.963096264744106
GO:0141110	transporter inhibitor activity	7/2977	45/18639	0.155555555555556	0.973933490090695	0.593157543732233	0.963096264744106
GO:0003720	telomerase activity	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:0004000	adenosine deaminase activity	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:0004032	aldose reductase (NADPH) activity	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:0004126	cytidine deaminase activity	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:0004300	enoyl-CoA hydratase activity	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:0015368	calcium:monoatomic cation antiporter activity	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:0016208	AMP binding	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:0034452	dynactin binding	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:0035497	cAMP response element binding	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:0036009	protein-glutamine N-methyltransferase activity	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:0097677	STAT family protein binding	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:1990459	transferrin receptor binding	2/2977	12/18639	0.166666666666667	1.04350016795432	0.59354483974441	0.963096264744106
GO:0042910	xenobiotic transmembrane transporter activity	5/2977	32/18639	0.15625	0.978281407457172	0.595654437710746	0.965292788016018
GO:0020037	heme binding	22/2977	142/18639	0.154929577464789	0.97001424063359	0.597581929023257	0.96718900299455
GO:0005525	GTP binding	59/2977	378/18639	0.156084656084656	0.977246189036582	0.59920354601872	0.968585985146716
GO:0038024	cargo receptor activity	10/2977	65/18639	0.153846153846154	0.963230924265523	0.6037213642268	0.971279721730503
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	3/2977	19/18639	0.157894736842105	0.988579106483037	0.604672966934808	0.971279721730503
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/2977	19/18639	0.157894736842105	0.988579106483037	0.604672966934808	0.971279721730503
GO:0097001	ceramide binding	3/2977	19/18639	0.157894736842105	0.988579106483037	0.604672966934808	0.971279721730503
GO:1990380	K48-linked deubiquitinase activity	3/2977	19/18639	0.157894736842105	0.988579106483037	0.604672966934808	0.971279721730503
GO:0043548	phosphatidylinositol 3-kinase binding	4/2977	26/18639	0.153846153846154	0.963230924265523	0.614883747003509	0.984222410535826
GO:0120014	phospholipid transfer activity	4/2977	26/18639	0.153846153846154	0.963230924265523	0.614883747003509	0.984222410535826
GO:1902936	phosphatidylinositol bisphosphate binding	17/2977	111/18639	0.153153153153153	0.958892046228291	0.615042665315261	0.984222410535826
GO:0043178	alcohol binding	14/2977	92/18639	0.152173913043478	0.952761022914811	0.622283620009297	0.991559494619033
GO:0033293	monocarboxylic acid binding	12/2977	79/18639	0.151898734177215	0.951038127755833	0.622648614477664	0.991559494619033
GO:0019001	guanyl nucleotide binding	62/2977	400/18639	0.155	0.970455156197514	0.623964059033803	0.991559494619033
GO:0032561	guanyl ribonucleotide binding	62/2977	400/18639	0.155	0.970455156197514	0.623964059033803	0.991559494619033
GO:0019239	deaminase activity	5/2977	33/18639	0.151515151515152	0.948636516322106	0.624286478992719	0.991559494619033
GO:0019956	chemokine binding	5/2977	33/18639	0.151515151515152	0.948636516322106	0.624286478992719	0.991559494619033
GO:0016251	RNA polymerase II general transcription initiation factor activity	8/2977	53/18639	0.150943396226415	0.945056755883155	0.626964651096564	0.994576222919642
GO:0005338	nucleotide-sugar transmembrane transporter activity	2/2977	13/18639	0.153846153846154	0.963230924265523	0.63870036513726	1
GO:0008417	fucosyltransferase activity	2/2977	13/18639	0.153846153846154	0.963230924265523	0.63870036513726	1
GO:0031994	insulin-like growth factor I binding	2/2977	13/18639	0.153846153846154	0.963230924265523	0.63870036513726	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/2977	13/18639	0.153846153846154	0.963230924265523	0.63870036513726	1
GO:0061459	L-arginine transmembrane transporter activity	2/2977	13/18639	0.153846153846154	0.963230924265523	0.63870036513726	1
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/2977	13/18639	0.153846153846154	0.963230924265523	0.63870036513726	1
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/2977	13/18639	0.153846153846154	0.963230924265523	0.63870036513726	1
GO:0016004	phospholipase activator activity	3/2977	20/18639	0.15	0.939150151158885	0.640855712528326	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/2977	20/18639	0.15	0.939150151158885	0.640855712528326	1
GO:0005504	fatty acid binding	7/2977	47/18639	0.148936170212766	0.932489511788964	0.64114231202877	1
GO:0140359	ABC-type transporter activity	7/2977	47/18639	0.148936170212766	0.932489511788964	0.64114231202877	1
GO:0001727	lipid kinase activity	6/2977	41/18639	0.146341463414634	0.916244049911107	0.657758469820817	1
GO:0033192	calmodulin-dependent protein phosphatase activity	12/2977	81/18639	0.148148148148148	0.927555704848281	0.65840853806934	1
GO:0140791	histone H2AXS140 phosphatase activity	12/2977	81/18639	0.148148148148148	0.927555704848281	0.65840853806934	1
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	12/2977	81/18639	0.148148148148148	0.927555704848281	0.65840853806934	1
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	12/2977	81/18639	0.148148148148148	0.927555704848281	0.65840853806934	1
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	12/2977	81/18639	0.148148148148148	0.927555704848281	0.65840853806934	1
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	12/2977	81/18639	0.148148148148148	0.927555704848281	0.65840853806934	1
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	12/2977	81/18639	0.148148148148148	0.927555704848281	0.65840853806934	1
GO:1990439	MAP kinase serine/threonine phosphatase activity	12/2977	81/18639	0.148148148148148	0.927555704848281	0.65840853806934	1
GO:0140693	molecular condensate scaffold activity	7/2977	48/18639	0.145833333333333	0.913062646960027	0.663856151158438	1
GO:0015174	basic amino acid transmembrane transporter activity	3/2977	21/18639	0.142857142857143	0.894428715389414	0.674637157695485	1
GO:0051428	peptide hormone receptor binding	3/2977	21/18639	0.142857142857143	0.894428715389414	0.674637157695485	1
GO:0072542	protein phosphatase activator activity	3/2977	21/18639	0.142857142857143	0.894428715389414	0.674637157695485	1
GO:0046625	sphingolipid binding	4/2977	28/18639	0.142857142857143	0.894428715389414	0.675061797742366	1
GO:0046875	ephrin receptor binding	4/2977	28/18639	0.142857142857143	0.894428715389414	0.675061797742366	1
GO:0051019	mitogen-activated protein kinase binding	4/2977	28/18639	0.142857142857143	0.894428715389414	0.675061797742366	1
GO:0033549	MAP kinase phosphatase activity	12/2977	82/18639	0.146341463414634	0.916244049911107	0.675565361583145	1
GO:0015179	L-amino acid transmembrane transporter activity	9/2977	62/18639	0.145161290322581	0.908854984992469	0.675695561483889	1
GO:0016229	steroid dehydrogenase activity	5/2977	35/18639	0.142857142857143	0.894428715389414	0.677734324936043	1
GO:0005161	platelet-derived growth factor receptor binding	2/2977	14/18639	0.142857142857143	0.894428715389414	0.679805445235891	1
GO:0008191	metalloendopeptidase inhibitor activity	2/2977	14/18639	0.142857142857143	0.894428715389414	0.679805445235891	1
GO:0031404	chloride ion binding	2/2977	14/18639	0.142857142857143	0.894428715389414	0.679805445235891	1
GO:0032036	myosin heavy chain binding	2/2977	14/18639	0.142857142857143	0.894428715389414	0.679805445235891	1
GO:0044548	S100 protein binding	2/2977	14/18639	0.142857142857143	0.894428715389414	0.679805445235891	1
GO:0046030	inositol trisphosphate phosphatase activity	2/2977	14/18639	0.142857142857143	0.894428715389414	0.679805445235891	1
GO:0061665	SUMO ligase activity	2/2977	14/18639	0.142857142857143	0.894428715389414	0.679805445235891	1
GO:1901474	azole transmembrane transporter activity	2/2977	14/18639	0.142857142857143	0.894428715389414	0.679805445235891	1
GO:0005543	phospholipid binding	76/2977	497/18639	0.152917505030181	0.957416653092894	0.681254958061632	1
GO:0008307	structural constituent of muscle	6/2977	42/18639	0.142857142857143	0.894428715389414	0.681447112085131	1
GO:0170055	lipid transmembrane transporter activity	8/2977	56/18639	0.142857142857143	0.894428715389414	0.690131623521215	1
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	12/2977	83/18639	0.144578313253012	0.905204964972419	0.692214296127898	1
GO:0004722	protein serine/threonine phosphatase activity	15/2977	103/18639	0.145631067961165	0.911796263261053	0.69271652117329	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	10/2977	70/18639	0.142857142857143	0.894428715389414	0.699280666233563	1
GO:0005484	SNAP receptor activity	5/2977	36/18639	0.138888888888889	0.869583473295264	0.70246695071807	1
GO:0016881	acid-amino acid ligase activity	3/2977	22/18639	0.136363636363636	0.853772864689895	0.706010349151675	1
GO:0031683	G-protein beta/gamma-subunit complex binding	3/2977	22/18639	0.136363636363636	0.853772864689895	0.706010349151675	1
GO:0140784	metal ion sensor activity	3/2977	22/18639	0.136363636363636	0.853772864689895	0.706010349151675	1
GO:0017018	myosin phosphatase activity	12/2977	84/18639	0.142857142857143	0.894428715389414	0.708340110250943	1
GO:0004175	endopeptidase activity	61/2977	405/18639	0.150617283950617	0.943014966595753	0.713607961508561	1
GO:0008514	organic anion transmembrane transporter activity	40/2977	269/18639	0.148698884758364	0.931003867319836	0.715093012997487	1
GO:0004089	carbonate dehydratase activity	2/2977	15/18639	0.133333333333333	0.834800134363453	0.717001616839857	1
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/2977	15/18639	0.133333333333333	0.834800134363453	0.717001616839857	1
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/2977	15/18639	0.133333333333333	0.834800134363453	0.717001616839857	1
GO:0005523	tropomyosin binding	2/2977	15/18639	0.133333333333333	0.834800134363453	0.717001616839857	1
GO:0010181	FMN binding	2/2977	15/18639	0.133333333333333	0.834800134363453	0.717001616839857	1
GO:0015116	sulfate transmembrane transporter activity	2/2977	15/18639	0.133333333333333	0.834800134363453	0.717001616839857	1
GO:0031005	filamin binding	2/2977	15/18639	0.133333333333333	0.834800134363453	0.717001616839857	1
GO:0004725	protein tyrosine phosphatase activity	14/2977	98/18639	0.142857142857143	0.894428715389414	0.717119187798497	1
GO:0022829	wide pore channel activity	5/2977	37/18639	0.135135135135135	0.846081217260257	0.725845982745093	1
GO:0098918	structural constituent of synapse	4/2977	30/18639	0.133333333333333	0.834800134363453	0.728373712254687	1
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	3/2977	23/18639	0.130434782608696	0.816652305355552	0.735007927566248	1
GO:0005283	amino acid:sodium symporter activity	3/2977	23/18639	0.130434782608696	0.816652305355552	0.735007927566248	1
GO:0043274	phospholipase binding	3/2977	23/18639	0.130434782608696	0.816652305355552	0.735007927566248	1
GO:0140103	catalytic activity, acting on a glycoprotein	3/2977	23/18639	0.130434782608696	0.816652305355552	0.735007927566248	1
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	3/2977	23/18639	0.130434782608696	0.816652305355552	0.735007927566248	1
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/2977	16/18639	0.125	0.782625125965737	0.750488528280766	1
GO:0004707	MAP kinase activity	2/2977	16/18639	0.125	0.782625125965737	0.750488528280766	1
GO:0015385	sodium:proton antiporter activity	2/2977	16/18639	0.125	0.782625125965737	0.750488528280766	1
GO:0015562	efflux transmembrane transporter activity	2/2977	16/18639	0.125	0.782625125965737	0.750488528280766	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/2977	16/18639	0.125	0.782625125965737	0.750488528280766	1
GO:0030275	LRR domain binding	2/2977	16/18639	0.125	0.782625125965737	0.750488528280766	1
GO:0034450	ubiquitin-ubiquitin ligase activity	2/2977	16/18639	0.125	0.782625125965737	0.750488528280766	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/2977	16/18639	0.125	0.782625125965737	0.750488528280766	1
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	2/2977	16/18639	0.125	0.782625125965737	0.750488528280766	1
GO:0008081	phosphoric diester hydrolase activity	12/2977	87/18639	0.137931034482759	0.863586345893227	0.753472954046098	1
GO:0005496	steroid binding	15/2977	108/18639	0.138888888888889	0.869583473295264	0.761131983911735	1
GO:0005315	phosphate transmembrane transporter activity	3/2977	24/18639	0.125	0.782625125965737	0.761693479154991	1
GO:0015295	solute:proton symporter activity	3/2977	24/18639	0.125	0.782625125965737	0.761693479154991	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/2977	24/18639	0.125	0.782625125965737	0.761693479154991	1
GO:0030215	semaphorin receptor binding	3/2977	24/18639	0.125	0.782625125965737	0.761693479154991	1
GO:0050431	transforming growth factor beta binding	3/2977	24/18639	0.125	0.782625125965737	0.761693479154991	1
GO:0060229	lipase activator activity	3/2977	24/18639	0.125	0.782625125965737	0.761693479154991	1
GO:1901681	sulfur compound binding	40/2977	275/18639	0.145454545454545	0.910691055669222	0.7657469717386	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/2977	32/18639	0.125	0.782625125965737	0.774852685989819	1
GO:0071813	lipoprotein particle binding	4/2977	32/18639	0.125	0.782625125965737	0.774852685989819	1
GO:0071814	protein-lipid complex binding	4/2977	32/18639	0.125	0.782625125965737	0.774852685989819	1
GO:0120015	sterol transfer activity	4/2977	32/18639	0.125	0.782625125965737	0.774852685989819	1
GO:0005085	guanyl-nucleotide exchange factor activity	33/2977	230/18639	0.143478260869565	0.898317535891107	0.776004146578135	1
GO:0015026	coreceptor activity	8/2977	61/18639	0.131147540983607	0.821114886259134	0.779241783810493	1
GO:0015278	intracellularly gated calcium channel activity	2/2977	17/18639	0.117647058823529	0.736588353850106	0.780501777286968	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/2977	17/18639	0.117647058823529	0.736588353850106	0.780501777286968	1
GO:0031489	myosin V binding	2/2977	17/18639	0.117647058823529	0.736588353850106	0.780501777286968	1
GO:0038191	neuropilin binding	2/2977	17/18639	0.117647058823529	0.736588353850106	0.780501777286968	1
GO:0051787	misfolded protein binding	2/2977	17/18639	0.117647058823529	0.736588353850106	0.780501777286968	1
GO:0043495	protein-membrane adaptor activity	6/2977	47/18639	0.127659574468085	0.79927672439054	0.783281557097366	1
GO:0000030	mannosyltransferase activity	3/2977	25/18639	0.12	0.751320120927108	0.786154029291951	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/2977	25/18639	0.12	0.751320120927108	0.786154029291951	1
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	3/2977	25/18639	0.12	0.751320120927108	0.786154029291951	1
GO:0120020	cholesterol transfer activity	3/2977	25/18639	0.12	0.751320120927108	0.786154029291951	1
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	5/2977	40/18639	0.125	0.782625125965737	0.787918083761841	1
GO:0030165	PDZ domain binding	11/2977	83/18639	0.132530120481928	0.829771217891384	0.793101216851844	1
GO:0008194	UDP-glycosyltransferase activity	20/2977	145/18639	0.137931034482759	0.863586345893227	0.79533220772663	1
GO:0030295	protein kinase activator activity	19/2977	139/18639	0.136690647482014	0.855820281631598	0.803320053003372	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	12/2977	91/18639	0.131868131868132	0.825626506513305	0.805918390858358	1
GO:0001530	lipopolysaccharide binding	5/2977	41/18639	0.121951219512195	0.763536708259256	0.805995807920316	1
GO:0140318	protein transporter activity	5/2977	41/18639	0.121951219512195	0.763536708259256	0.805995807920316	1
GO:0140828	metal cation:monoatomic cation antiporter activity	5/2977	41/18639	0.121951219512195	0.763536708259256	0.805995807920316	1
GO:0005516	calmodulin binding	29/2977	207/18639	0.140096618357488	0.877145068715223	0.806589408485894	1
GO:0004706	JUN kinase kinase kinase activity	2/2977	18/18639	0.111111111111111	0.695666778636211	0.80729634225851	1
GO:0031690	adrenergic receptor binding	2/2977	18/18639	0.111111111111111	0.695666778636211	0.80729634225851	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	3/2977	26/18639	0.115384615384615	0.722423193199142	0.808493631329574	1
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	3/2977	26/18639	0.115384615384615	0.722423193199142	0.808493631329574	1
GO:0051139	metal cation:proton antiporter activity	3/2977	26/18639	0.115384615384615	0.722423193199142	0.808493631329574	1
GO:0004713	protein tyrosine kinase activity	19/2977	140/18639	0.135714285714286	0.849707279619943	0.813048817414995	1
GO:0090482	vitamin transmembrane transporter activity	4/2977	34/18639	0.117647058823529	0.736588353850106	0.81481470426922	1
GO:0005506	iron ion binding	21/2977	154/18639	0.136363636363636	0.853772864689895	0.816150965965682	1
GO:0008013	beta-catenin binding	14/2977	106/18639	0.132075471698113	0.82692466139776	0.817957225871034	1
GO:0016247	channel regulator activity	23/2977	168/18639	0.136904761904762	0.857160852248189	0.819446426992013	1
GO:0019209	kinase activator activity	20/2977	148/18639	0.135135135135135	0.846081217260257	0.823688484066741	1
GO:0004382	GDP phosphatase activity	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0004955	prostaglandin receptor activity	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0005131	growth hormone receptor binding	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0008239	dipeptidyl-peptidase activity	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0015203	polyamine transmembrane transporter activity	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0015279	store-operated calcium channel activity	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0015643	toxic substance binding	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0019911	structural constituent of myelin sheath	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0031434	mitogen-activated protein kinase kinase binding	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0035256	G protein-coupled glutamate receptor binding	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0050308	sugar-phosphatase activity	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0051864	histone H3K36 demethylase activity	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0070513	death domain binding	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0070739	protein-glutamic acid ligase activity	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0070740	tubulin-glutamic acid ligase activity	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0141109	transporter activator activity	1/2977	10/18639	0.1	0.62610010077259	0.824593073255078	1
GO:0004683	calcium/calmodulin-dependent protein kinase activity	3/2977	27/18639	0.111111111111111	0.695666778636211	0.828827974134168	1
GO:0008320	protein transmembrane transporter activity	3/2977	27/18639	0.111111111111111	0.695666778636211	0.828827974134168	1
GO:0035255	ionotropic glutamate receptor binding	3/2977	27/18639	0.111111111111111	0.695666778636211	0.828827974134168	1
GO:0022840	leak channel activity	2/2977	19/18639	0.105263157894737	0.659052737655358	0.83113438641424	1
GO:0022842	narrow pore channel activity	2/2977	19/18639	0.105263157894737	0.659052737655358	0.83113438641424	1
GO:0034987	immunoglobulin receptor binding	2/2977	19/18639	0.105263157894737	0.659052737655358	0.83113438641424	1
GO:0070003	threonine-type peptidase activity	2/2977	19/18639	0.105263157894737	0.659052737655358	0.83113438641424	1
GO:0005154	epidermal growth factor receptor binding	4/2977	35/18639	0.114285714285714	0.715542972311531	0.83250249515092	1
GO:0141108	transporter regulator activity	23/2977	170/18639	0.135294117647059	0.847076606927622	0.835993088996758	1
GO:0061135	endopeptidase regulator activity	25/2977	184/18639	0.135869565217391	0.850679484745367	0.838605531595749	1
GO:0061134	peptidase regulator activity	31/2977	226/18639	0.13716814159292	0.858809872741163	0.847080238554415	1
GO:0019789	SUMO transferase activity	3/2977	28/18639	0.107142857142857	0.670821536542061	0.847279915301184	1
GO:0141052	histone H3 demethylase activity	3/2977	28/18639	0.107142857142857	0.670821536542061	0.847279915301184	1
GO:0015171	amino acid transmembrane transporter activity	13/2977	102/18639	0.127450980392157	0.797970716670948	0.84867849491013	1
GO:0004190	aspartic-type endopeptidase activity	4/2977	36/18639	0.111111111111111	0.695666778636211	0.848756938205026	1
GO:0016409	palmitoyltransferase activity	4/2977	36/18639	0.111111111111111	0.695666778636211	0.848756938205026	1
GO:0001972	retinoic acid binding	2/2977	20/18639	0.1	0.62610010077259	0.852276461290452	1
GO:0005326	neurotransmitter transmembrane transporter activity	2/2977	20/18639	0.1	0.62610010077259	0.852276461290452	1
GO:0010851	cyclase regulator activity	2/2977	20/18639	0.1	0.62610010077259	0.852276461290452	1
GO:0042288	MHC class I protein binding	2/2977	20/18639	0.1	0.62610010077259	0.852276461290452	1
GO:0001786	phosphatidylserine binding	7/2977	59/18639	0.11864406779661	0.742830628035276	0.852390710922591	1
GO:0004016	adenylate cyclase activity	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0004954	prostanoid receptor activity	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0005114	type II transforming growth factor beta receptor binding	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0005225	volume-sensitive anion channel activity	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0008046	axon guidance receptor activity	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0016594	glycine binding	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0019203	carbohydrate phosphatase activity	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0019215	intermediate filament binding	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0034056	estrogen response element binding	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0043522	leucine zipper domain binding	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0047676	arachidonate-CoA ligase activity	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0048185	activin binding	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0097493	structural molecule activity conferring elasticity	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0180030	inositol phosphate kinase activity	1/2977	11/18639	0.0909090909090909	0.569181909793264	0.852623908024504	1
GO:0046982	protein heterodimerization activity	52/2977	369/18639	0.140921409214092	0.882309085099585	0.857693602585648	1
GO:0050840	extracellular matrix binding	8/2977	67/18639	0.119402985074627	0.747582209877719	0.859458329248897	1
GO:0003730	mRNA 3'-UTR binding	36/2977	262/18639	0.137404580152672	0.860290214802032	0.860298978066288	1
GO:0030551	cyclic nucleotide binding	4/2977	37/18639	0.108108108108108	0.676864973808205	0.863655235836533	1
GO:0070001	aspartic-type peptidase activity	4/2977	37/18639	0.108108108108108	0.676864973808205	0.863655235836533	1
GO:0004629	phospholipase C activity	3/2977	29/18639	0.103448275862069	0.647689759419921	0.863975839780921	1
GO:0005416	amino acid:monoatomic cation symporter activity	3/2977	29/18639	0.103448275862069	0.647689759419921	0.863975839780921	1
GO:0099106	ion channel regulator activity	21/2977	160/18639	0.13125	0.821756382264024	0.864738398584896	1
GO:0019003	GDP binding	9/2977	75/18639	0.12	0.751320120927108	0.866346123827154	1
GO:0046943	carboxylic acid transmembrane transporter activity	25/2977	188/18639	0.132978723404255	0.832579921240146	0.866970484113717	1
GO:0003924	GTPase activity	46/2977	331/18639	0.138972809667674	0.870108901375805	0.868649182926758	1
GO:0001846	opsonin binding	2/2977	21/18639	0.0952380952380952	0.596285810259609	0.87097533535308	1
GO:0009931	calcium-dependent protein serine/threonine kinase activity	2/2977	21/18639	0.0952380952380952	0.596285810259609	0.87097533535308	1
GO:0009975	cyclase activity	2/2977	21/18639	0.0952380952380952	0.596285810259609	0.87097533535308	1
GO:0061891	calcium ion sensor activity	2/2977	21/18639	0.0952380952380952	0.596285810259609	0.87097533535308	1
GO:0005178	integrin binding	21/2977	161/18639	0.130434782608696	0.816652305355552	0.871782173362197	1
GO:0005342	organic acid transmembrane transporter activity	25/2977	189/18639	0.132275132275132	0.82817473647168	0.873430412147331	1
GO:0004859	phospholipase inhibitor activity	1/2977	12/18639	0.0833333333333333	0.521750083977158	0.876176550595421	1
GO:0005165	neurotrophin receptor binding	1/2977	12/18639	0.0833333333333333	0.521750083977158	0.876176550595421	1
GO:0005247	voltage-gated chloride channel activity	1/2977	12/18639	0.0833333333333333	0.521750083977158	0.876176550595421	1
GO:0008179	adenylate cyclase binding	1/2977	12/18639	0.0833333333333333	0.521750083977158	0.876176550595421	1
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/2977	12/18639	0.0833333333333333	0.521750083977158	0.876176550595421	1
GO:0008504	monoamine transmembrane transporter activity	1/2977	12/18639	0.0833333333333333	0.521750083977158	0.876176550595421	1
GO:0010853	cyclase activator activity	1/2977	12/18639	0.0833333333333333	0.521750083977158	0.876176550595421	1
GO:0015166	polyol transmembrane transporter activity	1/2977	12/18639	0.0833333333333333	0.521750083977158	0.876176550595421	1
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/2977	12/18639	0.0833333333333333	0.521750083977158	0.876176550595421	1
GO:0070008	serine-type exopeptidase activity	1/2977	12/18639	0.0833333333333333	0.521750083977158	0.876176550595421	1
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/2977	12/18639	0.0833333333333333	0.521750083977158	0.876176550595421	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/2977	12/18639	0.0833333333333333	0.521750083977158	0.876176550595421	1
GO:0140900	chloride:bicarbonate antiporter activity	1/2977	12/18639	0.0833333333333333	0.521750083977158	0.876176550595421	1
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	1/2977	12/18639	0.0833333333333333	0.521750083977158	0.876176550595421	1
GO:1990817	poly(A) RNA polymerase activity	1/2977	12/18639	0.0833333333333333	0.521750083977158	0.876176550595421	1
GO:0000146	microfilament motor activity	4/2977	38/18639	0.105263157894737	0.659052737655358	0.877276926208638	1
GO:0005109	frizzled binding	4/2977	38/18639	0.105263157894737	0.659052737655358	0.877276926208638	1
GO:0005501	retinoid binding	4/2977	38/18639	0.105263157894737	0.659052737655358	0.877276926208638	1
GO:0019840	isoprenoid binding	4/2977	38/18639	0.105263157894737	0.659052737655358	0.877276926208638	1
GO:0004180	carboxypeptidase activity	5/2977	46/18639	0.108695652173913	0.680543587796293	0.878654992016892	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/2977	30/18639	0.1	0.62610010077259	0.879042742839391	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	3/2977	30/18639	0.1	0.62610010077259	0.879042742839391	1
GO:0032452	histone demethylase activity	3/2977	30/18639	0.1	0.62610010077259	0.879042742839391	1
GO:0033612	receptor serine/threonine kinase binding	3/2977	30/18639	0.1	0.62610010077259	0.879042742839391	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/2977	22/18639	0.0909090909090909	0.569181909793264	0.887471833973221	1
GO:0005452	solute:inorganic anion antiporter activity	3/2977	31/18639	0.0967741935483871	0.605903323328313	0.892605939755583	1
GO:0047499	calcium-independent phospholipase A2 activity	3/2977	31/18639	0.0967741935483871	0.605903323328313	0.892605939755583	1
GO:0140457	protein demethylase activity	3/2977	31/18639	0.0967741935483871	0.605903323328313	0.892605939755583	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/2977	13/18639	0.0769230769230769	0.481615462132761	0.895966232716935	1
GO:0019855	calcium channel inhibitor activity	1/2977	13/18639	0.0769230769230769	0.481615462132761	0.895966232716935	1
GO:0031432	titin binding	1/2977	13/18639	0.0769230769230769	0.481615462132761	0.895966232716935	1
GO:0035325	Toll-like receptor binding	1/2977	13/18639	0.0769230769230769	0.481615462132761	0.895966232716935	1
GO:0039706	co-receptor binding	1/2977	13/18639	0.0769230769230769	0.481615462132761	0.895966232716935	1
GO:0045159	myosin II binding	1/2977	13/18639	0.0769230769230769	0.481615462132761	0.895966232716935	1
GO:0089720	caspase binding	1/2977	13/18639	0.0769230769230769	0.481615462132761	0.895966232716935	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	10/2977	86/18639	0.116279069767442	0.728023372991384	0.898598488463465	1
GO:0032451	demethylase activity	4/2977	40/18639	0.1	0.62610010077259	0.901011791001493	1
GO:0016493	C-C chemokine receptor activity	2/2977	23/18639	0.0869565217391304	0.544434870237035	0.90199220601198	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	2/2977	23/18639	0.0869565217391304	0.544434870237035	0.90199220601198	1
GO:0099186	structural constituent of postsynapse	2/2977	23/18639	0.0869565217391304	0.544434870237035	0.90199220601198	1
GO:0015106	bicarbonate transmembrane transporter activity	3/2977	32/18639	0.09375	0.586968844474303	0.9047873108348	1
GO:0022884	macromolecule transmembrane transporter activity	3/2977	32/18639	0.09375	0.586968844474303	0.9047873108348	1
GO:0047498	calcium-dependent phospholipase A2 activity	3/2977	32/18639	0.09375	0.586968844474303	0.9047873108348	1
GO:0004620	phospholipase activity	13/2977	109/18639	0.119266055045872	0.746724890829694	0.905131574882614	1
GO:0035254	glutamate receptor binding	5/2977	49/18639	0.102040816326531	0.638877653849582	0.909991223955462	1
GO:0004867	serine-type endopeptidase inhibitor activity	11/2977	95/18639	0.115789473684211	0.724958011420893	0.910010082005468	1
GO:0120013	lipid transfer activity	7/2977	65/18639	0.107692307692308	0.674261646985866	0.912077941268841	1
GO:0004065	arylsulfatase activity	1/2977	14/18639	0.0714285714285714	0.447214357694707	0.912593985600092	1
GO:0004705	JUN kinase activity	1/2977	14/18639	0.0714285714285714	0.447214357694707	0.912593985600092	1
GO:0005313	L-glutamate transmembrane transporter activity	1/2977	14/18639	0.0714285714285714	0.447214357694707	0.912593985600092	1
GO:0005545	1-phosphatidylinositol binding	1/2977	14/18639	0.0714285714285714	0.447214357694707	0.912593985600092	1
GO:0015386	potassium:proton antiporter activity	1/2977	14/18639	0.0714285714285714	0.447214357694707	0.912593985600092	1
GO:0019992	diacylglycerol binding	1/2977	14/18639	0.0714285714285714	0.447214357694707	0.912593985600092	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/2977	14/18639	0.0714285714285714	0.447214357694707	0.912593985600092	1
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/2977	14/18639	0.0714285714285714	0.447214357694707	0.912593985600092	1
GO:0042043	neurexin family protein binding	1/2977	14/18639	0.0714285714285714	0.447214357694707	0.912593985600092	1
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/2977	14/18639	0.0714285714285714	0.447214357694707	0.912593985600092	1
GO:0004866	endopeptidase inhibitor activity	20/2977	161/18639	0.124223602484472	0.777764100338621	0.914001235251676	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	2/2977	24/18639	0.0833333333333333	0.521750083977158	0.914746635726252	1
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	2/2977	24/18639	0.0833333333333333	0.521750083977158	0.914746635726252	1
GO:0004806	triacylglycerol lipase activity	2/2977	24/18639	0.0833333333333333	0.521750083977158	0.914746635726252	1
GO:0019957	C-C chemokine binding	2/2977	24/18639	0.0833333333333333	0.521750083977158	0.914746635726252	1
GO:0030552	cAMP binding	2/2977	24/18639	0.0833333333333333	0.521750083977158	0.914746635726252	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/2977	24/18639	0.0833333333333333	0.521750083977158	0.914746635726252	1
GO:0030414	peptidase inhibitor activity	21/2977	169/18639	0.124260355029586	0.777994208060615	0.91831924293537	1
GO:0032813	tumor necrosis factor receptor superfamily binding	5/2977	50/18639	0.1	0.62610010077259	0.918733028444975	1
GO:0042056	chemoattractant activity	4/2977	42/18639	0.0952380952380952	0.596285810259609	0.920595060373433	1
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	35/2977	268/18639	0.130597014925373	0.817668042053755	0.921432713051891	1
GO:0015020	glucuronosyltransferase activity	3/2977	34/18639	0.0882352941176471	0.552441265387579	0.925467478093709	1
GO:0051427	hormone receptor binding	3/2977	34/18639	0.0882352941176471	0.552441265387579	0.925467478093709	1
GO:0052866	phosphatidylinositol phosphate phosphatase activity	3/2977	34/18639	0.0882352941176471	0.552441265387579	0.925467478093709	1
GO:0001848	complement binding	2/2977	25/18639	0.08	0.500880080618072	0.925928601503148	1
GO:0004879	nuclear receptor activity	6/2977	59/18639	0.101694915254237	0.63671196688738	0.926159732273207	1
GO:0015459	potassium channel regulator activity	6/2977	59/18639	0.101694915254237	0.63671196688738	0.926159732273207	1
GO:0004467	long-chain fatty acid-CoA ligase activity	1/2977	15/18639	0.0666666666666667	0.417400067181727	0.926564869082966	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/2977	15/18639	0.0666666666666667	0.417400067181727	0.926564869082966	1
GO:0004953	icosanoid receptor activity	1/2977	15/18639	0.0666666666666667	0.417400067181727	0.926564869082966	1
GO:0015250	water channel activity	1/2977	15/18639	0.0666666666666667	0.417400067181727	0.926564869082966	1
GO:0017081	chloride channel regulator activity	1/2977	15/18639	0.0666666666666667	0.417400067181727	0.926564869082966	1
GO:0034483	heparan sulfate sulfotransferase activity	1/2977	15/18639	0.0666666666666667	0.417400067181727	0.926564869082966	1
GO:0045504	dynein heavy chain binding	1/2977	15/18639	0.0666666666666667	0.417400067181727	0.926564869082966	1
GO:0050700	CARD domain binding	1/2977	15/18639	0.0666666666666667	0.417400067181727	0.926564869082966	1
GO:0140161	monocarboxylate:sodium symporter activity	1/2977	15/18639	0.0666666666666667	0.417400067181727	0.926564869082966	1
GO:0016597	amino acid binding	5/2977	51/18639	0.0980392156862745	0.613823628208421	0.926715821021741	1
GO:0098531	ligand-modulated transcription factor activity	6/2977	60/18639	0.1	0.62610010077259	0.933045635001719	1
GO:0017022	myosin binding	8/2977	76/18639	0.105263157894737	0.659052737655358	0.934052935530227	1
GO:0004623	phospholipase A2 activity	3/2977	35/18639	0.0857142857142857	0.536657229233648	0.934182945244596	1
GO:0005343	organic acid:sodium symporter activity	3/2977	35/18639	0.0857142857142857	0.536657229233648	0.934182945244596	1
GO:0001637	G protein-coupled chemoattractant receptor activity	2/2977	26/18639	0.0769230769230769	0.481615462132761	0.935714849017612	1
GO:0004950	chemokine receptor activity	2/2977	26/18639	0.0769230769230769	0.481615462132761	0.935714849017612	1
GO:0005227	calcium-activated cation channel activity	2/2977	26/18639	0.0769230769230769	0.481615462132761	0.935714849017612	1
GO:0008157	protein phosphatase 1 binding	2/2977	26/18639	0.0769230769230769	0.481615462132761	0.935714849017612	1
GO:0004708	MAP kinase kinase activity	1/2977	16/18639	0.0625	0.391312562982869	0.938303291803112	1
GO:0005024	transforming growth factor beta receptor activity	1/2977	16/18639	0.0625	0.391312562982869	0.938303291803112	1
GO:0005149	interleukin-1 receptor binding	1/2977	16/18639	0.0625	0.391312562982869	0.938303291803112	1
GO:0015378	sodium:chloride symporter activity	1/2977	16/18639	0.0625	0.391312562982869	0.938303291803112	1
GO:0019841	retinol binding	1/2977	16/18639	0.0625	0.391312562982869	0.938303291803112	1
GO:0022841	potassium ion leak channel activity	1/2977	16/18639	0.0625	0.391312562982869	0.938303291803112	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/2977	16/18639	0.0625	0.391312562982869	0.938303291803112	1
GO:0055102	lipase inhibitor activity	1/2977	16/18639	0.0625	0.391312562982869	0.938303291803112	1
GO:0035401	histone H3Y41 kinase activity	13/2977	115/18639	0.11304347826087	0.707765331308145	0.938484079373636	1
GO:0140801	histone H2AXY142 kinase activity	13/2977	115/18639	0.11304347826087	0.707765331308145	0.938484079373636	1
GO:0015291	secondary active transmembrane transporter activity	37/2977	287/18639	0.128919860627178	0.807167377302642	0.938579305797935	1
GO:0005246	calcium channel regulator activity	5/2977	53/18639	0.0943396226415094	0.590660472426972	0.940616087021549	1
GO:0004033	aldo-keto reductase (NADPH) activity	3/2977	36/18639	0.0833333333333333	0.521750083977158	0.941948945884557	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/2977	36/18639	0.0833333333333333	0.521750083977158	0.941948945884557	1
GO:0005044	scavenger receptor activity	2/2977	27/18639	0.0740740740740741	0.463777852424141	0.944265799008288	1
GO:0015252	proton channel activity	2/2977	27/18639	0.0740740740740741	0.463777852424141	0.944265799008288	1
GO:0023026	MHC class II protein complex binding	2/2977	27/18639	0.0740740740740741	0.463777852424141	0.944265799008288	1
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	2/2977	27/18639	0.0740740740740741	0.463777852424141	0.944265799008288	1
GO:0003925	G protein activity	5/2977	54/18639	0.0925925925925926	0.579722315530176	0.946634294099972	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/2977	17/18639	0.0588235294117647	0.368294176925053	0.948165886460371	1
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/2977	17/18639	0.0588235294117647	0.368294176925053	0.948165886460371	1
GO:0008484	sulfuric ester hydrolase activity	1/2977	17/18639	0.0588235294117647	0.368294176925053	0.948165886460371	1
GO:0008569	minus-end-directed microtubule motor activity	1/2977	17/18639	0.0588235294117647	0.368294176925053	0.948165886460371	1
GO:0019198	transmembrane receptor protein phosphatase activity	1/2977	17/18639	0.0588235294117647	0.368294176925053	0.948165886460371	1
GO:0030548	acetylcholine receptor regulator activity	1/2977	17/18639	0.0588235294117647	0.368294176925053	0.948165886460371	1
GO:0045236	CXCR chemokine receptor binding	1/2977	17/18639	0.0588235294117647	0.368294176925053	0.948165886460371	1
GO:0070492	oligosaccharide binding	1/2977	17/18639	0.0588235294117647	0.368294176925053	0.948165886460371	1
GO:0045499	chemorepellent activity	2/2977	28/18639	0.0714285714285714	0.447214357694707	0.951726251601142	1
GO:0051959	dynein light intermediate chain binding	2/2977	28/18639	0.0714285714285714	0.447214357694707	0.951726251601142	1
GO:0001217	DNA-binding transcription repressor activity	35/2977	278/18639	0.12589928057554	0.788255522555419	0.952339969589793	1
GO:0001784	phosphotyrosine residue binding	4/2977	47/18639	0.0851063829787234	0.532851149593694	0.955211384244709	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/2977	18/18639	0.0555555555555556	0.347833389318105	0.956452330236951	1
GO:0005372	water transmembrane transporter activity	1/2977	18/18639	0.0555555555555556	0.347833389318105	0.956452330236951	1
GO:0015280	ligand-gated sodium channel activity	1/2977	18/18639	0.0555555555555556	0.347833389318105	0.956452330236951	1
GO:0015373	monoatomic anion:sodium symporter activity	1/2977	18/18639	0.0555555555555556	0.347833389318105	0.956452330236951	1
GO:0017075	syntaxin-1 binding	1/2977	18/18639	0.0555555555555556	0.347833389318105	0.956452330236951	1
GO:0034185	apolipoprotein binding	1/2977	18/18639	0.0555555555555556	0.347833389318105	0.956452330236951	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/2977	18/18639	0.0555555555555556	0.347833389318105	0.956452330236951	1
GO:0050811	GABA receptor binding	1/2977	18/18639	0.0555555555555556	0.347833389318105	0.956452330236951	1
GO:0099602	neurotransmitter receptor regulator activity	1/2977	18/18639	0.0555555555555556	0.347833389318105	0.956452330236951	1
GO:0030246	carbohydrate binding	35/2977	280/18639	0.125	0.782625125965737	0.957089264138161	1
GO:0099604	ligand-gated calcium channel activity	2/2977	29/18639	0.0689655172413793	0.431793172946614	0.958226282106344	1
GO:0019955	cytokine binding	16/2977	144/18639	0.111111111111111	0.695666778636211	0.961866787742845	1
GO:0035591	signaling adaptor activity	14/2977	129/18639	0.108527131782946	0.679488481458625	0.962280989119126	1
GO:0005229	intracellularly calcium-gated chloride channel activity	1/2977	19/18639	0.0526315789473684	0.329526368827679	0.963414438227102	1
GO:0016918	retinal binding	1/2977	19/18639	0.0526315789473684	0.329526368827679	0.963414438227102	1
GO:0022821	solute:potassium antiporter activity	1/2977	19/18639	0.0526315789473684	0.329526368827679	0.963414438227102	1
GO:0042834	peptidoglycan binding	1/2977	19/18639	0.0526315789473684	0.329526368827679	0.963414438227102	1
GO:0043395	heparan sulfate proteoglycan binding	1/2977	19/18639	0.0526315789473684	0.329526368827679	0.963414438227102	1
GO:0141147	intracellularly calcium-gated channel activity	1/2977	19/18639	0.0526315789473684	0.329526368827679	0.963414438227102	1
GO:0022839	monoatomic ion-gated channel activity	2/2977	30/18639	0.0666666666666667	0.417400067181727	0.96388224919684	1
GO:0070566	adenylyltransferase activity	2/2977	30/18639	0.0666666666666667	0.417400067181727	0.96388224919684	1
GO:1990782	protein tyrosine kinase binding	12/2977	117/18639	0.102564102564103	0.642153949510349	0.971435247204786	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	5/2977	60/18639	0.0833333333333333	0.521750083977158	0.972495715677094	1
GO:0005123	death receptor binding	1/2977	21/18639	0.0476190476190476	0.298142905129805	0.974178228938355	1
GO:0005248	voltage-gated sodium channel activity	1/2977	21/18639	0.0476190476190476	0.298142905129805	0.974178228938355	1
GO:0015125	bile acid transmembrane transporter activity	1/2977	21/18639	0.0476190476190476	0.298142905129805	0.974178228938355	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	4/2977	52/18639	0.0769230769230769	0.481615462132761	0.975399994016062	1
GO:0005253	monoatomic anion channel activity	10/2977	103/18639	0.0970873786407767	0.607864175507369	0.97577374200856	1
GO:0008375	acetylglucosaminyltransferase activity	3/2977	43/18639	0.0697674418604651	0.43681402379483	0.976594114902335	1
GO:0004896	cytokine receptor activity	9/2977	96/18639	0.09375	0.586968844474303	0.978185220924067	1
GO:0005544	calcium-dependent phospholipid binding	4/2977	53/18639	0.0754716981132075	0.472528377941577	0.978239496627859	1
GO:0008146	sulfotransferase activity	4/2977	53/18639	0.0754716981132075	0.472528377941577	0.978239496627859	1
GO:0017046	peptide hormone binding	4/2977	53/18639	0.0754716981132075	0.472528377941577	0.978239496627859	1
GO:0005243	gap junction channel activity	1/2977	22/18639	0.0454545454545455	0.284590954896632	0.978307104889076	1
GO:0015377	chloride:monoatomic cation symporter activity	1/2977	22/18639	0.0454545454545455	0.284590954896632	0.978307104889076	1
GO:0030547	signaling receptor inhibitor activity	3/2977	44/18639	0.0681818181818182	0.426886432344948	0.979518465412043	1
GO:0048306	calcium-dependent protein binding	7/2977	80/18639	0.0875	0.547837588176016	0.979605603237484	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/2977	34/18639	0.0588235294117647	0.368294176925053	0.97997210543564	1
GO:0016298	lipase activity	13/2977	130/18639	0.1	0.62610010077259	0.981490245415254	1
GO:0030971	receptor tyrosine kinase binding	7/2977	81/18639	0.0864197530864197	0.541074161161497	0.981629935353882	1
GO:0000149	SNARE binding	10/2977	106/18639	0.0943396226415094	0.590660472426972	0.981630789677485	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/2977	23/18639	0.0434782608695652	0.272217435118517	0.981775963928944	1
GO:0005212	structural constituent of eye lens	1/2977	23/18639	0.0434782608695652	0.272217435118517	0.981775963928944	1
GO:0016849	phosphorus-oxygen lyase activity	1/2977	23/18639	0.0434782608695652	0.272217435118517	0.981775963928944	1
GO:0015293	symporter activity	15/2977	146/18639	0.102739726027397	0.643253528191017	0.981922858229604	1
GO:0008009	chemokine activity	3/2977	45/18639	0.0666666666666667	0.417400067181727	0.982092091565687	1
GO:0015149	hexose transmembrane transporter activity	1/2977	24/18639	0.0416666666666667	0.260875041988579	0.984690282546452	1
GO:0055056	D-glucose transmembrane transporter activity	1/2977	24/18639	0.0416666666666667	0.260875041988579	0.984690282546452	1
GO:0001216	DNA-binding transcription activator activity	62/2977	491/18639	0.126272912423625	0.790594831932802	0.984802733979433	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	19/2977	181/18639	0.104972375690608	0.657232149982277	0.98679670973994	1
GO:0003707	nuclear steroid receptor activity	1/2977	25/18639	0.04	0.250440040309036	0.987138685923256	1
GO:0005251	delayed rectifier potassium channel activity	1/2977	25/18639	0.04	0.250440040309036	0.987138685923256	1
GO:0015271	outward rectifier potassium channel activity	1/2977	25/18639	0.04	0.250440040309036	0.987138685923256	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/2977	25/18639	0.04	0.250440040309036	0.987138685923256	1
GO:0015645	fatty acid ligase activity	1/2977	25/18639	0.04	0.250440040309036	0.987138685923256	1
GO:0120515	fatty acid-CoA ligase activity	1/2977	25/18639	0.04	0.250440040309036	0.987138685923256	1
GO:0023023	MHC protein complex binding	2/2977	37/18639	0.0540540540540541	0.338432486904103	0.987220811669809	1
GO:0043394	proteoglycan binding	2/2977	37/18639	0.0540540540540541	0.338432486904103	0.987220811669809	1
GO:0038187	pattern recognition receptor activity	3/2977	48/18639	0.0625	0.391312562982869	0.988085056152555	1
GO:0004435	phosphatidylinositol phospholipase C activity	1/2977	26/18639	0.0384615384615385	0.240807731066381	0.989195639399482	1
GO:0015145	monosaccharide transmembrane transporter activity	1/2977	26/18639	0.0384615384615385	0.240807731066381	0.989195639399482	1
GO:0030247	polysaccharide binding	1/2977	26/18639	0.0384615384615385	0.240807731066381	0.989195639399482	1
GO:0019199	transmembrane receptor protein kinase activity	6/2977	78/18639	0.0769230769230769	0.481615462132761	0.990244936058419	1
GO:0008395	steroid hydroxylase activity	1/2977	27/18639	0.037037037037037	0.23188892621207	0.990923710183759	1
GO:0016405	CoA-ligase activity	1/2977	27/18639	0.037037037037037	0.23188892621207	0.990923710183759	1
GO:0005006	epidermal growth factor receptor activity	3/2977	50/18639	0.06	0.375660060463554	0.990951533193702	1
GO:0005007	fibroblast growth factor receptor activity	3/2977	50/18639	0.06	0.375660060463554	0.990951533193702	1
GO:0015144	carbohydrate transmembrane transporter activity	2/2977	40/18639	0.05	0.313050050386295	0.991887823114557	1
GO:0019905	syntaxin binding	4/2977	61/18639	0.0655737704918033	0.410557443129567	0.992076415604541	1
GO:0005010	insulin-like growth factor receptor activity	3/2977	51/18639	0.0588235294117647	0.368294176925053	0.992122576378769	1
GO:0005030	neurotrophin receptor activity	3/2977	51/18639	0.0588235294117647	0.368294176925053	0.992122576378769	1
GO:0008201	heparin binding	17/2977	172/18639	0.0988372093023256	0.618819867042676	0.992224336305379	1
GO:0005242	inward rectifier potassium channel activity	1/2977	28/18639	0.0357142857142857	0.223607178847354	0.992375467909041	1
GO:0050698	proteoglycan sulfotransferase activity	1/2977	28/18639	0.0357142857142857	0.223607178847354	0.992375467909041	1
GO:0051119	sugar transmembrane transporter activity	1/2977	28/18639	0.0357142857142857	0.223607178847354	0.992375467909041	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	59/2977	484/18639	0.121900826446281	0.763221197222785	0.992549710086714	1
GO:0008509	monoatomic anion transmembrane transporter activity	14/2977	149/18639	0.0939597315436242	0.588281973880286	0.99290758526981	1
GO:0015294	solute:monoatomic cation symporter activity	10/2977	116/18639	0.0862068965517241	0.539741466183267	0.993015530054864	1
GO:0042287	MHC protein binding	2/2977	41/18639	0.0487804878048781	0.305414683303702	0.993035295656892	1
GO:0030159	signaling receptor complex adaptor activity	3/2977	52/18639	0.0576923076923077	0.361211596599571	0.993146407951996	1
GO:0004181	metallocarboxypeptidase activity	1/2977	29/18639	0.0344827586206897	0.215896586473307	0.993595081687709	1
GO:0001540	amyloid-beta binding	6/2977	83/18639	0.072289156626506	0.45260248248621	0.994541652706642	1
GO:0005254	chloride channel activity	6/2977	83/18639	0.072289156626506	0.45260248248621	0.994541652706642	1
GO:0005245	voltage-gated calcium channel activity	2/2977	43/18639	0.0465116279069767	0.291209349196553	0.994873517281671	1
GO:0005539	glycosaminoglycan binding	25/2977	242/18639	0.103305785123967	0.646797624765072	0.995672035516157	1
GO:0042605	peptide antigen binding	2/2977	45/18639	0.0444444444444444	0.278266711454484	0.996233204119106	1
GO:0030296	protein tyrosine kinase activator activity	1/2977	33/18639	0.0303030303030303	0.189727303264421	0.996810880841917	1
GO:0015370	solute:sodium symporter activity	5/2977	79/18639	0.0632911392405063	0.39626588656493	0.997225387973032	1
GO:0004252	serine-type endopeptidase activity	16/2977	176/18639	0.0909090909090909	0.569181909793264	0.997282250714719	1
GO:0005004	GPI-linked ephrin receptor activity	2/2977	49/18639	0.0408163265306122	0.255551061539833	0.997975997360604	1
GO:0005008	hepatocyte growth factor receptor activity	2/2977	49/18639	0.0408163265306122	0.255551061539833	0.997975997360604	1
GO:0005009	insulin receptor activity	2/2977	49/18639	0.0408163265306122	0.255551061539833	0.997975997360604	1
GO:0005011	macrophage colony-stimulating factor receptor activity	2/2977	49/18639	0.0408163265306122	0.255551061539833	0.997975997360604	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	2/2977	49/18639	0.0408163265306122	0.255551061539833	0.997975997360604	1
GO:0005020	stem cell factor receptor activity	2/2977	49/18639	0.0408163265306122	0.255551061539833	0.997975997360604	1
GO:0008288	boss receptor activity	2/2977	49/18639	0.0408163265306122	0.255551061539833	0.997975997360604	1
GO:0036332	placental growth factor receptor activity	2/2977	49/18639	0.0408163265306122	0.255551061539833	0.997975997360604	1
GO:0038062	protein tyrosine kinase collagen receptor activity	2/2977	49/18639	0.0408163265306122	0.255551061539833	0.997975997360604	1
GO:0060175	brain-derived neurotrophic factor receptor activity	2/2977	49/18639	0.0408163265306122	0.255551061539833	0.997975997360604	1
GO:0045505	dynein intermediate chain binding	1/2977	36/18639	0.0277777777777778	0.173916694659053	0.998109868888837	1
GO:0005017	platelet-derived growth factor receptor activity	2/2977	50/18639	0.04	0.250440040309036	0.998268683367558	1
GO:0005019	platelet-derived growth factor beta-receptor activity	2/2977	50/18639	0.04	0.250440040309036	0.998268683367558	1
GO:0015108	chloride transmembrane transporter activity	9/2977	121/18639	0.0743801652892562	0.465694289830852	0.998364484723707	1
GO:0070851	growth factor receptor binding	11/2977	139/18639	0.079136690647482	0.495474899891978	0.998395442688309	1
GO:0030280	structural constituent of skin epidermis	1/2977	37/18639	0.027027027027027	0.169216243452051	0.998412342700477	1
GO:0015103	inorganic anion transmembrane transporter activity	14/2977	165/18639	0.0848484848484849	0.531236449140379	0.998412802194862	1
GO:0005021	vascular endothelial growth factor receptor activity	2/2977	51/18639	0.0392156862745098	0.245529451283369	0.998519544877305	1
GO:0005272	sodium channel activity	2/2977	51/18639	0.0392156862745098	0.245529451283369	0.998519544877305	1
GO:0042562	hormone binding	6/2977	94/18639	0.0638297872340425	0.39963836219527	0.998558538979903	1
GO:0042277	peptide binding	24/2977	249/18639	0.0963855421686747	0.603469976648279	0.99866621159883	1
GO:0008236	serine-type peptidase activity	17/2977	194/18639	0.0876288659793814	0.548644418202785	0.998888168427066	1
GO:0005003	ephrin receptor activity	2/2977	53/18639	0.0377358490566038	0.236264188970789	0.9989185349709	1
GO:0005005	transmembrane-ephrin receptor activity	2/2977	53/18639	0.0377358490566038	0.236264188970789	0.9989185349709	1
GO:0038064	collagen receptor activity	2/2977	53/18639	0.0377358490566038	0.236264188970789	0.9989185349709	1
GO:0071855	neuropeptide receptor binding	1/2977	40/18639	0.025	0.156525025193147	0.9990591409287	1
GO:0016500	protein-hormone receptor activity	3/2977	67/18639	0.0447761194029851	0.280343328704145	0.999203435349437	1
GO:0017171	serine hydrolase activity	17/2977	198/18639	0.0858585858585859	0.537560692582527	0.999236926558306	1
GO:0042379	chemokine receptor binding	3/2977	72/18639	0.0416666666666667	0.260875041988579	0.999619595911622	1
GO:0099095	ligand-gated monoatomic anion channel activity	1/2977	47/18639	0.0212765957446809	0.133212787398423	0.999722565554465	1
GO:0015085	calcium ion transmembrane transporter activity	10/2977	147/18639	0.0680272108843537	0.425918435899721	0.999755013675589	1
GO:0015081	sodium ion transmembrane transporter activity	11/2977	164/18639	0.0670731707317073	0.419945189542591	0.999898037685825	1
GO:0004497	monooxygenase activity	5/2977	106/18639	0.0471698113207547	0.295330236213486	0.99992428758356	1
GO:0005126	cytokine receptor binding	23/2977	275/18639	0.0836363636363636	0.523647357009802	0.999936763317827	1
GO:0140375	immune receptor activity	9/2977	156/18639	0.0576923076923077	0.361211596599571	0.999974110333386	1
GO:0099094	ligand-gated monoatomic cation channel activity	7/2977	136/18639	0.0514705882352941	0.322257404809421	0.99997589767041	1
GO:0005179	hormone activity	6/2977	132/18639	0.0454545454545455	0.284590954896632	0.999990426612362	1
GO:0005267	potassium channel activity	5/2977	124/18639	0.0403225806451613	0.252459718053464	0.999994065057253	1
GO:0005262	calcium channel activity	5/2977	131/18639	0.0381679389312977	0.238969504111676	0.999997845742357	1
GO:0001664	G protein-coupled receptor binding	21/2977	297/18639	0.0707070707070707	0.442697040950316	0.999998879885091	1
GO:0015079	potassium ion transmembrane transporter activity	7/2977	160/18639	0.04375	0.273918794088008	0.999999069563166	1
GO:0005249	voltage-gated potassium channel activity	2/2977	98/18639	0.0204081632653061	0.127775530769916	0.999999262249154	1
GO:0030527	structural constituent of chromatin	2/2977	98/18639	0.0204081632653061	0.127775530769916	0.999999262249154	1
GO:0005244	voltage-gated monoatomic ion channel activity	8/2977	173/18639	0.046242774566474	0.289526058160735	0.999999284442485	1
GO:0008083	growth factor activity	7/2977	162/18639	0.0432098765432099	0.270537080580749	0.999999295240515	1
GO:0022832	voltage-gated channel activity	8/2977	175/18639	0.0457142857142857	0.286217188924613	0.999999454775133	1
GO:0022834	ligand-gated channel activity	8/2977	188/18639	0.0425531914893617	0.266425574796847	0.999999908836127	1
GO:0022843	voltage-gated monoatomic cation channel activity	4/2977	143/18639	0.027972027972028	0.175132895321004	0.999999947113883	1
GO:0046873	metal ion transmembrane transporter activity	34/2977	450/18639	0.0755555555555556	0.473053409472623	0.999999975915789	1
GO:0015276	ligand-gated monoatomic ion channel activity	7/2977	186/18639	0.0376344086021505	0.235629070183233	0.999999976456147	1
GO:0008528	G protein-coupled peptide receptor activity	2/2977	122/18639	0.0163934426229508	0.102639360782392	0.99999998639141	1
GO:0001653	peptide receptor activity	2/2977	128/18639	0.015625	0.0978281407457172	0.9999999950203	1
GO:0003823	antigen binding	5/2977	174/18639	0.028735632183908	0.179913822061089	0.99999999654765	1
GO:0022836	gated channel activity	17/2977	318/18639	0.0534591194968553	0.334707601041951	0.999999998972443	1
GO:0005125	cytokine activity	9/2977	234/18639	0.0384615384615385	0.240807731066381	0.99999999928703	1
GO:0005216	monoatomic ion channel activity	26/2977	448/18639	0.0580357142857143	0.363361665626949	0.999999999992496	1
GO:0005261	monoatomic cation channel activity	15/2977	341/18639	0.0439882697947214	0.275410601512869	0.999999999996854	1
GO:0045182	translation regulator activity	13/2977	356/18639	0.0365168539325843	0.22863205927089	0.999999999999984	1
GO:0030371	translation repressor activity	6/2977	329/18639	0.0182370820668693	0.114182389198649	1	1