category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Genetic Information Processing	Translation	hsa03010	Ribosome	80/363	222/9376	9.30782021691113	RPLP0/RPL29/RPL18A/RPL14/RPS2/RPS18/RPSA/RPS7/RPL18/RPL37/RPS19/RPS3/RPS4X/RPS27/RPL10A/RPS14/RPL8/RPL37A/RPS24/RPL39/RPL6/RPS5/RPL11/RPL7A/RPS3A/RPL13/RPL23A/RPS11/RPL13A/RPLP1/RPS29/RPS6/RPS13/RPLP2/RPS12/RPS15/RPL21/RPL27A/RPL24/RPS27A/RPL5/RPL9/RPL32/RPL10/RPL7/RPL36/RPS8/RPL23/RPS23/RPS16/RPL38/RPS26/UBA52/RPL31/RPL28/RPL26/RPL15/RPS25/RPL35/RPS20/RPL12/RPL4/RPL19/RPL41/RPL34/RPL22/RPL30/RPL27/RPS15A/RPL35A/RPL3/RPS10/RPS9/RPS21/FAU/RPL17/RPL36A/MRPL23/MRPS15/MRPL11	25.1398329820842
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	78/363	238/9376	8.4650322939093	RPLP0/RPL29/RPL18A/RPL14/RPS2/RPS18/RPSA/RPS7/RPL18/RPL37/RPS19/RPS3/RPS4X/RPS27/RPL10A/RPS14/RPL8/RPL37A/RPS24/RPL39/RPL6/RPS5/RPL11/RPL7A/RPS3A/RPL13/RPL23A/RPS11/RPL13A/RPLP1/RPS29/RPS6/RPS13/RPLP2/RPS12/RPS15/RPL21/RPL27A/RPL24/RPS27A/RPL5/RPL9/RPL32/RPL10/RPL7/RPL36/RPS8/RPL23/RPS23/RPS16/RPL38/RPS26/UBA52/RPL31/RPL28/RPL26/RPL15/RPS25/RPL35/RPS20/RPL12/RPL4/RPL19/RPL41/RPL34/RPL22/RPL30/RPL27/RPS15A/RPL35A/CFD/RPL3/RPS10/RPS9/RPS21/FAU/RPL17/RPL36A	23.4098622224752
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	24/363	205/9376	3.02390647046966	COL1A2/COL1A1/COL3A1/GAPDH/SLC2A1/UQCRH/MMP2/MT-CO2/PPP1CB/UQCR10/MT-CO3/SLC25A6/COX5B/NDUFA11/COX7B/NDUFB11/NDUFA4/COX6C/PARP1/NDUFS5/NDUFC2/COX5A/NDUFA6/COX4I1	5.87980993658742
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	23/363	233/9376	2.54966362808735	COL1A2/TPM1/COL1A1/COL3A1/TPM2/DSC2/ACTB/ENO1/DSP/DSG2/TNNI2/PKP2/FBLN1/COL4A1/MYL4/LMNB1/DIAPH3/COL27A1/SDC4/ACTG1/COL5A2/MYH10/CSRP2	4.80701310056055
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	18/363	157/9376	2.96130968047586	LEP/UQCRH/PPARG/MT-CO2/UQCR10/MT-CO3/COX5B/NDUFA11/COX7B/NDUFB11/NDUFA4/XBP1/COX6C/NDUFS5/NDUFC2/COX5A/NDUFA6/COX4I1	4.97345686679106
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	25/363	268/9376	2.40944040129929	RPS27A/TUBA1C/UBA52/TUBB/UQCRH/TUBA1B/MT-CO2/UQCR10/MT-CO3/CALM3/SLC25A6/COX5B/NDUFA11/COX7B/NDUFB11/NDUFA4/XBP1/COX6C/NDUFS5/NDUFC2/PSMA4/COX5A/NDUFA6/GNAS/COX4I1	4.69793352753915
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	10/363	59/9376	4.3778306952421	GSTP1/PRDX6/GPX3/MGST3/RRM2/SMS/GPX4/MGST1/IDH2/GPX8	5.22312117163577
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	16/363	138/9376	2.99468998283228	UQCRH/MT-CO2/UQCR10/MT-CO3/COX5B/NDUFA11/COX7B/NDUFB11/NDUFA4/COX6C/NDUFS5/NDUFC2/COX5A/NDUFA6/COX4I1/ATP6V1B1	4.73729288641966
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	12/363	87/9376	3.56264842785219	TPM1/TPM2/UQCRH/MT-CO2/UQCR10/MT-CO3/COX5B/MYL4/COX7B/COX6C/COX5A/COX4I1	4.81912774904703
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	17/363	158/9376	2.77909125780242	CDKN1C/CCNB1/CCNE1/PTTG1/SKP2/WEE1/CDC20/CCNB2/MAD2L1/CDK7/ANAPC11/CDK1/YWHAE/CDT1/AURKB/CCNA2/MCM4	4.52598054073331
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	8/363	51/9376	4.05163938853778	ACTB/KDELR2/PDIA4/SEC61G/KDELR1/ACTG1/GNAS/ATP6V1B1	4.38528824521295
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	20/363	235/9376	2.19822988101518	RPS6/ACTB/UQCRH/PPARG/MT-CO2/UQCR10/MT-CO3/COX5B/NDUFA11/COX7B/NDUFB11/NDUFA4/COX6C/NDUFS5/ACTG1/NDUFC2/COX5A/NDUFA6/GNAS/COX4I1	3.73320198016201
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	27/363	368/9376	1.89507725476105	TUBA1C/ACTB/PFN1/TUBB/HNRNPA1/GPX3/UQCRH/TUBA1B/MT-CO2/UQCR10/MT-CO3/COX5B/NDUFA11/COX7B/NDUFB11/NDUFA4/XBP1/CHCHD10/COX6C/GPX8/NDUFS5/ACTG1/NDUFC2/PSMA4/COX5A/NDUFA6/COX4I1	3.5153980458174
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	16/363	174/9376	2.37509895190146	CALR/P4HB/SSR3/TUSC3/PDIA6/OSTC/PDIA4/SSR4/SSR2/DDOST/HSP90AB1/XBP1/SEC61G/ERP29/SAR1A/CRYAB	3.67427557605403
NA	NA	hsa04382	Cornified envelope formation	18/363	217/9376	2.14251437711848	KRT19/KRT18/KRT8/S100A11/KRT7/CLDN7/CLDN4/KRT23/DSP/DSG2/PRSS8/PKP2/COL4A1/PADI1/PKP3/CLDN19/CLDN10/CLDN6	3.41721084848289
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	23/363	308/9376	1.92880397839076	TUBA1C/TUBB/GPX3/UQCRH/TUBA1B/PPARG/MT-CO2/UQCR10/MT-CO3/SLC25A6/COX5B/NDUFA11/COX7B/NDUFB11/NDUFA4/COX6C/GPX8/NDUFS5/NDUFC2/PSMA4/COX5A/NDUFA6/COX4I1	3.32619674847983
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	9/363	75/9376	3.0995041322314	GAPDH/ALDOA/PHGDH/ENO1/IDH2/CBS/PGK1/TPI1/TKT	3.66342081298667
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	9/363	75/9376	3.0995041322314	CCNB1/CCNE1/PERP/RRM2/CCNB2/IGFBP3/CDK1/SIVA1/GTSE1	3.66342081298667
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	18/363	227/9376	2.04813048385335	MGST3/UQCRH/MT-CO2/MGST1/UQCR10/MT-CO3/SLC25A6/COX5B/NDUFA11/COX7B/NDUFB11/NDUFA4/COX6C/NDUFS5/NDUFC2/COX5A/NDUFA6/COX4I1	3.20808400678971
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	16/363	200/9376	2.06633608815427	RPS3/TUBA1C/EZR/GAPDH/ACTB/TUBB/CLDN7/TUBA1B/CLDN4/NCL/TMED10/CLDN19/ACTG1/CLDN10/CLDN6/MYH10	3.05905065049113
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	20/363	275/9376	1.87848735286752	TUBA1C/TUBB/UQCRH/TUBA1B/MT-CO2/UQCR10/MT-CO3/SLC25A6/COX5B/NDUFA11/COX7B/NDUFB11/NDUFA4/COX6C/NDUFS5/NDUFC2/PSMA4/COX5A/NDUFA6/COX4I1	2.96730076451658
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	11/363	116/9376	2.44932079414838	GCSH/GAPDH/ALDOA/PHGDH/ENO1/IDH2/PGK1/TPI1/ACAT2/TKT/GLDC	3.15204413421217
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	9/363	85/9376	2.734856587263	RRM2/IMPDH2/TYMS/AK5/TK1/ADK/NT5E/ENPP1/HDDC2	3.2243789515566
Metabolism	Lipid metabolism	hsa00100	Steroid biosynthesis	4/363	20/9376	5.16584022038568	SQLE/MSMO1/FDFT1/DHCR24	3.74262888548425
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	12/363	138/9376	2.24601748712421	CCNB1/CCNE1/PTTG1/CDC20/CCNB2/MAD2L1/ANAPC11/PPP1CB/CDK1/YWHAE/CALM3/AURKA	2.95923167455158
Cellular Processes	Cell motility	hsa04814	Motor proteins	15/363	194/9376	1.99710317798415	TPM1/TUBA1C/TPM2/ACTB/TUBB/TUBA1B/TNNI2/MYL4/CENPE/KIF23/ACTA2/ACTG1/KIF2C/KIF21A/MYH10	2.81628489837214
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	25/363	388/9376	1.66425264832013	TUBA1C/GAPDH/TUBB/UQCRH/TUBA1B/MT-CO2/UQCR10/MT-CO3/CALM3/SLC25A6/COX5B/NDUFA11/COX7B/NDUFB11/NDUFA4/XBP1/HSD17B10/COX6C/NDUFS5/MME/NDUFC2/PSMA4/COX5A/NDUFA6/COX4I1	2.68177223855721
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	12/363	142/9376	2.18274938889536	GSTP1/ACTB/MGST3/CTSL/MMP2/MGST1/CALM3/HSP90AB1/SDC4/RAC3/ACTG1/GPC1	2.85000902057195
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	6/363	50/9376	3.0995041322314	HBA2/HBA1/GYPA/HBB/GYPB/CR1L	2.98715869578179
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	10/363	116/9376	2.22665526740762	EZR/ACTB/CLDN7/CLDN4/MMP2/JAM3/CLDN19/ACTG1/CLDN10/CLDN6	2.66778173330811
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	5/363	39/9376	3.31143603870877	GCSH/TYMS/CBS/GLDC/AHCY	2.902784327347
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	5/363	41/9376	3.1499025734059	GCSH/PHGDH/CBS/GLDC/ALAS2	2.76858468354962
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	6/363	59/9376	2.62669841714526	RRM2/TYMS/TK1/NT5E/ENPP1/HDDC2	2.5153548857335
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	9/363	110/9376	2.11329827197596	RPS6/GAPDH/SLC2A1/ALDOA/LDHB/ENO1/PGK1/ANGPT1/FLT1	2.35703480092561
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	7/363	76/9376	2.3790053646513	EZR/ACTB/CA2/CALM3/GAST/ACTG1/GNAS	2.4223424653794
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	27/363	480/9376	1.45289256198347	RPS27A/TUBA1C/UBA52/TUBB/GPX3/UQCRH/TUBA1B/MT-CO2/UQCR10/MT-CO3/CALM3/SLC25A6/COX5B/NDUFA11/COX7B/NDUFB11/NDUFA4/XBP1/HSD17B10/COX6C/GPX8/NDUFS5/NDUFC2/PSMA4/COX5A/NDUFA6/COX4I1	2.04419670970678
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	12/363	170/9376	1.823237724842	TUBA1C/EZR/ACTB/CLDN7/TUBA1B/CLDN4/JAM3/CLDN19/ACTG1/CLDN10/CLDN6/MYH10	2.17379459380598
NA	NA	hsa03272	Virion - Hepatitis viruses	5/363	48/9376	2.69054178145087	CLDN7/CLDN4/CLDN19/CLDN10/CLDN6	2.35644074737912
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	11/363	155/9376	1.83304007820137	HLA-G/TUBA1C/ACTB/CALR/FCGR2B/TUBB/TUBA1B/CTSL/SEC61G/ACTG1/ATP6V1B1	2.09868374805863
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	11/363	157/9376	1.80968924917969	HLA-G/CCNB1/CCNE1/CCNB2/IGFBP3/PPP1CB/CDK1/CALM3/SLC25A6/CCNA2/MYBL2	2.05319669626196
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	6/363	67/9376	2.31306278524732	GAPDH/ALDOA/LDHB/ENO1/PGK1/TPI1	2.16458998197673
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	8/363	103/9376	2.00615154189735	COL1A2/COL1A1/COL3A1/COL4A1/COL27A1/MME/COL5A2/COL25A1	2.0605167284292
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	11/363	160/9376	1.77575757575758	HLA-G/CLDN7/CLDN4/JAM3/PTPRF/PTPRS/SDC4/CDH1/CLDN19/CLDN10/CLDN6	1.98618203282573
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	5/363	52/9376	2.48357702903157	CGA/CYP11A1/HSD3B1/HSD17B1/GNAS	2.15285561896666
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	14/363	224/9376	1.61432506887052	HLA-G/CCNE1/SLC2A1/CALR/PTTG1/RAN/RANBP1/CDC20/CCNB2/MAD2L1/ANAPC11/SLC25A6/CCNA2/MSX2	1.86753395437513
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	13/363	204/9376	1.64597850159347	COL1A2/RPS6/COL1A1/EZR/ACTB/IGF2/CTSL/MMP2/PPP1CB/SDC4/GPC3/ACTG1/GPC1	1.87199804400619
Organismal Systems	Immune system	hsa04611	Platelet activation	9/363	126/9376	1.84494293585203	COL1A2/COL1A1/COL3A1/ACTB/PPP1CB/VAMP8/P2RY1/ACTG1/GNAS	1.91622300952285
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	5/363	54/9376	2.391592694623	SMS/LDHB/PHGDH/CBS/AHCY	2.05806333661435
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	8/363	110/9376	1.87848735286752	CCNB1/CCNB2/MAD2L1/ANAPC11/CDK1/HSP90AB1/AURKA/CCNA2	1.8599016229556
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	6/363	76/9376	2.0391474554154	SCD/PPARG/PLTP/PLIN2/FADS2/HMGCS1	1.82535258641301
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	6/363	78/9376	1.98686162322526	HSPD1/ENO1/LSM4/LSM7/LSM3/LSM5	1.75635805247633
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	9/363	137/9376	1.69680883151354	TUBA1C/ACTB/TUBA1B/BIRC5/CTSL/CTSV/LMNB1/PARP1/ACTG1	1.64879139266309
Metabolism	Lipid metabolism	hsa01040	Biosynthesis of unsaturated fatty acids	3/363	27/9376	2.8699112335476	SCD/FADS2/ELOVL6	1.95265068462658
Organismal Systems	Digestive system	hsa04978	Mineral absorption	5/363	61/9376	2.1171476313056	MT1H/MT1G/STEAP1/MT1E/STEAP2	1.75666246647671
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	6/363	82/9376	1.88994154404354	GSTP1/MGST3/RRM2/IMPDH2/MGST1/TK1	1.62431905165148
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	3/363	30/9376	2.58292011019284	GGH/TYMS/FOLR1	1.7426533312414
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	6/363	86/9376	1.80203728618105	DSC2/ACTB/DSP/DSG2/PKP2/ACTG1	1.49947832576984
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	3/363	31/9376	2.49960010663823	GCSH/ACAT2/GLDC	1.67830512927866
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	8/363	128/9376	1.61432506887052	RRM2/IMPDH2/AK5/PAICS/ADK/NT5E/ENPP1/HDDC2	1.40437657713517
NA	NA	hsa04518	Integrin signaling	9/363	154/9376	1.50949876569711	COL1A2/COL1A1/ACTB/PGF/COL4A1/CDH1/RAC3/ACTG1/FLT1	1.27936717250639
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	3/363	35/9376	2.21393152302243	AKR1B1/ALDOA/TPI1	1.44389559186106
Metabolism	Carbohydrate metabolism	hsa00040	Pentose and glucuronate interconversions	3/363	36/9376	2.1524334251607	AKR1B1/DCXR/UGP2	1.39026606921064
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	3/363	36/9376	2.1524334251607	PYGL/UGP2/ENPP1	1.39026606921064
Genetic Information Processing	Replication and repair	hsa03030	DNA replication	3/363	36/9376	2.1524334251607	RPA3/SSBP1/MCM4	1.39026606921064
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	5/363	75/9376	1.72194674012856	GSTP1/MGST3/TOP2A/BIRC5/MGST1	1.25972350949549
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	5/363	75/9376	1.72194674012856	CGA/GPX3/PDIA4/GPX8/GNAS	1.25972350949549
Metabolism	Metabolism of cofactors and vitamins	hsa00785	Lipoic acid metabolism	2/363	19/9376	2.7188632738872	GCSH/GLDC	1.5050609342982
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	4/363	56/9376	1.84494293585203	BNIP3/HSPD1/SAR1A/CR1L	1.27267555337835
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	3/363	37/9376	2.094259548805	HBA2/HBA1/HBB	1.33836719989573
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	4/363	57/9376	1.8125755159248	SCD/FADS2/ACAT2/ELOVL6	1.23486866201415
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	3/363	38/9376	2.0391474554154	QPRT/NT5E/ENPP1	1.28809029228897
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	11/363	212/9376	1.34019439679817	ACTB/PFN1/PGF/CALM3/ANGPT1/CDH1/RAC3/P2RY1/ACTG1/GNAS/FLT1	1.00544151088065
Genetic Information Processing	Replication and repair	hsa03440	Homologous recombination	3/363	41/9376	1.88994154404354	RPA3/SSBP1/RAD51	1.14604194560786
Metabolism	Metabolism of terpenoids and polyketides	hsa00900	Terpenoid backbone biosynthesis	2/363	23/9376	2.24601748712421	HMGCS1/ACAT2	1.20065118394418
Genetic Information Processing	Replication and repair	hsa03430	Mismatch repair	2/363	23/9376	2.24601748712421	RPA3/SSBP1	1.20065118394418
Genetic Information Processing	Transcription	hsa03040	Spliceosome	12/363	243/9376	1.27551610379893	HNRNPA1/SNRPD2/SNRPF/SNRPD1/LSM4/LSM7/SNRPB/LSM3/HNRNPC/LSM5/SNRPG/SNRPE	0.873268231717256
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	7/363	130/9376	1.39080313625768	COL1A2/COL1A1/COL3A1/MMP2/COL4A1/ACTA2/GNAS	0.900444681257513
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	3/363	44/9376	1.7610818933133	TUSC3/OSTC/DDOST	1.01548760841377
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	5/363	89/9376	1.45107871359148	COL1A2/COL1A1/HMMR/COL4A1/SDC4	0.858052535474674
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	5/363	89/9376	1.45107871359148	TUBA1C/TUBB/TUBA1B/CDK1/GNAS	0.858052535474674
Metabolism	Lipid metabolism	hsa00592	alpha-Linolenic acid metabolism	2/363	26/9376	1.98686162322526	PLA2G2A/FADS2	1.01121008979224
Metabolism	Carbohydrate metabolism	hsa00650	Butanoate metabolism	2/363	27/9376	1.9132741556984	HMGCS1/ACAT2	0.953684524368009
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	3/363	48/9376	1.61432506887052	HMGCS1/ACAT2/HSD17B10	0.856305736011205
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	4/363	70/9376	1.47595434868162	HLA-G/ACTB/RAC3/ACTG1	0.802115780048285
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	5/363	93/9376	1.38866672591013	ACTB/PTPRF/CDH1/RAC3/ACTG1	0.755925378651154
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	5/363	93/9376	1.38866672591013	CCNE1/CKS1B/SKP2/CKS2/COL4A1	0.755925378651154
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	7/363	139/9376	1.30075113462949	KRT19/KRT18/MMP2/KRT23/CALM3/HSP90AB1/GNAS	0.716891560844843
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	4/363	71/9376	1.45516625926357	SLC2A1/SLC16A3/LDHB/IDH2	0.772583292091845
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	2/363	28/9376	1.84494293585203	AKR1B1/GGH	0.898568744931961
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	2/363	28/9376	1.84494293585203	CA2/ATP6V1B1	0.898568744931961
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	5/363	95/9376	1.3594316369436	CTSL/ANGPT1/CCL3L1/FLT1/ATP6V1B1	0.706618465421321
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	7/363	142/9376	1.27327047685562	RPS27A/UBA52/UBE2C/SKP2/CDC20/UBE2S/ANAPC11	0.658485501160917
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	5/363	99/9376	1.304505106158	KRT19/KRT18/FCGR2B/CFD/KRT23	0.611241262076372
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	2/363	31/9376	1.66640007109215	ALDOA/TKT	0.745813935671741
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	2/363	31/9376	1.66640007109215	SEC11A/SEC61G	0.745813935671741
NA	NA	hsa04981	Folate transport and metabolism	2/363	31/9376	1.66640007109215	TYMS/FOLR1	0.745813935671741
Genetic Information Processing	Replication and repair	hsa03460	Fanconi anemia pathway	3/363	54/9376	1.4349556167738	RPA3/RAD51/UBE2T	0.643267395262628
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	5/363	101/9376	1.27867332187764	COL1A2/COL1A1/COL3A1/MMP2/COL4A1	0.565071478872762
Metabolism	Carbohydrate metabolism	hsa00052	Galactose metabolism	2/363	32/9376	1.61432506887052	AKR1B1/UGP2	0.698571844153921
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	5/363	103/9376	1.25384471368584	COL1A2/COL1A1/COL3A1/COL4A1/GNAS	0.5198533791308
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	3/363	56/9376	1.38370720188902	TUSC3/OSTC/DDOST	0.577950006774052
NA	NA	hsa04517	IgSF CAM signaling	13/363	299/9376	1.1230087435621	TUBA1C/EZR/ACTB/TUBB/TUBA1B/JAM3/ROBO2/PTPRF/PTPRS/CDH1/IL1RAP/ACTG1/MYH10	0.433815109529918
Genetic Information Processing	Information processing in viruses	hsa03265	Virion - Ebolavirus, Lyssavirus and Morbillivirus	1/363	12/9376	2.1524334251607	FCGR2B	0.801641204218066
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	5/363	105/9376	1.22996195723468	TPM1/TPM2/ACTB/ACTG1/GNAS	0.475545000823784
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	9/363	203/9376	1.14513699466678	COL1A2/COL1A1/ACTB/PGF/PPP1CB/COL4A1/RAC3/ACTG1/FLT1	0.419541293972836
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	5/363	106/9376	1.21835854254379	GSTP1/CCNE1/SPINT1/HSP90AB1/FOLR1	0.453719576086568
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	4/363	82/9376	1.25996102936236	HLA-G/CALR/CTSL/HSP90AB1	0.474480212218919
NA	NA	hsa04519	Cadherin signaling	17/363	404/9376	1.086872323596	KRT19/KRT18/KRT8/KRT7/DSC2/ACTB/PCDH10/KRT23/DSP/DSG2/PPP1CB/YWHAE/PKP2/CDH1/RAC3/PKP3/ACTG1	0.35820509030523
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	5/363	107/9376	1.2069720141088	SLC2A1/LDHB/PYGL/CALM3/GNAS	0.432107036897411
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	7/363	156/9376	1.15900261354807	CLDN7/CLDN4/YWHAE/EIF3E/CLDN19/CLDN10/CLDN6	0.401888303538739
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	6/363	134/9376	1.15653139262366	PLA2G2A/PPP1CB/CALM3/ACTA2/GNAS/MYH10	0.366247890007384
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	2/363	37/9376	1.39617303253667	PPARG/CDH1	0.484551396247204
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	3/363	63/9376	1.22996195723468	PTGDS/PLA2G2A/GPX4	0.367524025535779
Metabolism	Metabolism of cofactors and vitamins	hsa00730	Thiamine metabolism	1/363	15/9376	1.72194674012856	AK5	0.561557111944748
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	9/363	214/9376	1.08627481269792	HLA-G/CCNB1/CALR/WEE1/CCNB2/CDK1/CALM3/RAC3/AP1M2	0.256212334300654
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	5/363	115/9376	1.1230087435621	NACA/GCM1/GATA3/MMP15/GNAS	0.266354614879662
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	3/363	65/9376	1.19211697393516	CYP11A1/HSD3B1/GNAS	0.311909438993436
Metabolism	Amino acid metabolism	hsa00360	Phenylalanine metabolism	1/363	16/9376	1.61432506887052	MIF	0.493542515356742
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	3/363	66/9376	1.1740545955422	CYP11A1/HSD3B1/HSD17B1	0.284765181653785
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	2/363	41/9376	1.25996102936236	MMP2/CDH1	0.334770576636981
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	4/363	93/9376	1.1109333807281	CGA/MMP2/CALM3/GNAS	0.215756462392239
Metabolism	Energy metabolism	hsa00910	Nitrogen metabolism	1/363	17/9376	1.51936477070167	CA2	0.430116882809726
NA	NA	hsa03273	Virion - Lassa virus and SFTS virus	1/363	17/9376	1.51936477070167	MYH10	0.430116882809726
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	2/363	43/9376	1.20135819078737	PLA2G2A/ACAT2	0.265581097006096
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	3/363	69/9376	1.1230087435621	PPP1CB/CALM3/GNAS	0.205806902399975
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	2/363	44/9376	1.1740545955422	HLA-G/HSPD1	0.232235566912658
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	3/363	70/9376	1.10696576151122	GSTP1/MGST3/MGST1	0.180267131649681
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	5/363	122/9376	1.0585738156528	LEP/SCD/PPARG/CCNA2/EEF2	0.130684159484389
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	5/363	122/9376	1.0585738156528	DIO2/ACTB/SLC2A1/DIO3/ACTG1	0.130684159484389
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	6/363	149/9376	1.04010205779577	NDUFA11/NDUFB11/NDUFA4/NDUFS5/NDUFC2/NDUFA6	0.0990224797020086
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	4/363	98/9376	1.05425310620116	CYP11A1/CALM3/HSD3B1/GNAS	0.108346460254247
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	4/363	99/9376	1.0436040849264	PPP1CB/CALM3/IL1RAP/GNAS	0.0875276485126268
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	4/363	99/9376	1.0436040849264	TPM1/TPM2/ACTB/ACTG1	0.0875276485126268
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	3/363	73/9376	1.06147401788747	GSTP1/MGST3/MGST1	0.105814646136393
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	8/363	205/9376	1.00796882348989	HLA-G/CCNE1/SKP2/RANBP1/CDC20/CDK1/YWHAE/CCNA2	0.023150856140047
Metabolism	Glycan biosynthesis and metabolism	hsa00541	Biosynthesis of various nucleotide sugars	1/363	20/9376	1.29146005509642	UGP2	0.261850374344818
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	2/363	47/9376	1.09911494050759	LDHB/ACAT2	0.136701969700428
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	6/363	154/9376	1.00633251046474	TPM1/TPM2/PPP1CB/CALM3/MYL4/GNAS	0.0159011298036397
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	6/363	154/9376	1.00633251046474	ACTB/PPP1CB/CALM3/EEF2/ACTG1/GNAS	0.0159011298036397
Metabolism	Glycan biosynthesis and metabolism	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/363	21/9376	1.22996195723468	DSEL	0.211713237285619
Metabolism	Metabolism of cofactors and vitamins	hsa00770	Pantothenate and CoA biosynthesis	1/363	21/9376	1.22996195723468	ENPP1	0.211713237285619
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	6/363	157/9376	0.987103226825288	SLC2A1/CALR/PPARG/CEBPB/SLC16A1/BSG	-0.0327034255445343
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	6/363	157/9376	0.987103226825288	ACTB/BIRC5/PPP1CB/YWHAE/CDH1/ACTG1	-0.0327034255445343
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	3/363	77/9376	1.00633251046474	RALBP1/RAC3/RAD51	0.0111971480378665
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	2/363	50/9376	1.03316804407714	SMS/CKB	0.0471912437637284
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	4/363	105/9376	0.983969565787748	RPS27A/UBA52/BNIP3/TOMM20	-0.033149799829245
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	3/363	78/9376	0.99343081161263	ACTB/CDH1/ACTG1	-0.0116914536454298
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	3/363	79/9376	0.980855738047913	GSTP1/MGST3/MGST1	-0.0342913847803731
Organismal Systems	Endocrine system	hsa04614	Renin-angiotensin system	1/363	23/9376	1.1230087435621	MME	0.118530113035728
Organismal Systems	Excretory system	hsa04964	Proximal tubule bicarbonate reclamation	1/363	23/9376	1.1230087435621	CA2	0.118530113035728
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	4/363	109/9376	0.947860590896454	GATA3/EBI3/HSP90AB1/IL1RAP	-0.109878832852826
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	4/363	109/9376	0.947860590896454	SLC2A1/PPP1CB/PYGL/PTPRF	-0.109878832852826
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	5/363	138/9376	0.935840619635086	RPS6/PPP1CB/PYGL/CALM3/PTPRF	-0.152375446217578
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	2/363	54/9376	0.956637077849199	CGA/HLA-G	-0.0641305754132341
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	9/363	248/9376	0.937350039989336	RPS3/TUBA1C/GAPDH/ACTB/PFN1/TUBB/TUBA1B/HSP90AB1/ACTG1	-0.200661053494253
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	3/363	83/9376	0.933585581997411	PRDX5/IDH2/ECH1	-0.121962892044636
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	5/363	140/9376	0.922471467926013	RPS6/CALM3/MYL4/CDH1/ACTA2	-0.185476068647961
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	6/363	170/9376	0.911618862421002	GSTP1/ACTB/IGF2/MGST3/MGST1/ACTG1	-0.233374192248687
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	7/363	201/9376	0.899524416485068	PPARG/CEBPB/IGFBP3/SPINT1/MYCN/CCNA2/FLT1	-0.288974681995655
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	3/363	88/9376	0.880540946656649	TFPI/CFD/CR1L	-0.225945432641738
Metabolism	Lipid metabolism	hsa00062	Fatty acid elongation	1/363	28/9376	0.922471467926013	ELOVL6	-0.0824490185149495
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/363	59/9376	0.87556613904842	CGA/GNAS	-0.19241140016877
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	8/363	232/9376	0.890662106963047	EZR/ACTB/PFN1/PPP1CB/DIAPH3/RAC3/ACTG1/MYH10	-0.338415970180081
Organismal Systems	Sensory system	hsa04744	Phototransduction	1/363	29/9376	0.890662106963047	CALM3	-0.118341710839501
Organismal Systems	Digestive system	hsa04976	Bile secretion	3/363	90/9376	0.860973370064279	SLC2A1/CA2/GNAS	-0.265955622245864
Metabolism	Carbohydrate metabolism	hsa00020	Citrate cycle (TCA cycle)	1/363	30/9376	0.860973370064279	IDH2	-0.153055873274132
Metabolism	Lipid metabolism	hsa00591	Linoleic acid metabolism	1/363	30/9376	0.860973370064279	PLA2G2A	-0.153055873274132
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	2/363	63/9376	0.819974638156456	CDK7/RPA3	-0.287715613829778
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	8/363	238/9376	0.868208440400954	PGF/IGF2/RALBP1/PLA2G2A/CALM3/ANGPT1/RAC3/FLT1	-0.413289873483338
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	5/363	154/9376	0.838610425387285	QPRT/GGH/AK5/UGP2/ALAS2	-0.405254217763944
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/363	32/9376	0.807162534435262	LDHB	-0.219282641662666
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/363	32/9376	0.807162534435262	BIRC5	-0.219282641662666
Metabolism	Global and overview maps	hsa01210	2-Oxocarboxylic acid metabolism	1/363	33/9376	0.782703063694799	IDH2	-0.250941022864668
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	1/363	33/9376	0.782703063694799	VAMP8	-0.250941022864668
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	2/363	67/9376	0.771020928415772	PPP1CB/CALM3	-0.377473042418299
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	3/363	100/9376	0.774876033057851	CXCL14/CCR7/CCL3L1	-0.454198429413231
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	3/363	100/9376	0.774876033057851	GYPA/MME/CR1L	-0.454198429413231
Organismal Systems	Endocrine system	hsa04924	Renin secretion	2/363	69/9376	0.748672495708069	CALM3/GNAS	-0.420498036549121
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	2/363	70/9376	0.737977174340811	LEP/SLC2A1	-0.441581516748923
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	3/363	102/9376	0.759682385350835	PLA2G2A/CA2/GNAS	-0.489729662776929
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	4/363	133/9376	0.776818078253485	CCNB1/SKP2/BNIP3/CCNB2	-0.52021470220677
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/363	71/9376	0.727583129631785	JAM3/ATP6V1B1	-0.462390869813046
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/363	103/9376	0.752306828211506	CALR/CCL3L1/GNAS	-0.507255520401469
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/363	37/9376	0.698086516268335	MIF	-0.369264407401318
Metabolism	Global and overview maps	hsa01250	Biosynthesis of nucleotide sugars	1/363	37/9376	0.698086516268335	UGP2	-0.369264407401318
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	1/363	38/9376	0.679715818471799	UGP2	-0.397012900190641
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	2/363	73/9376	0.707649345258312	RAN/PPIA	-0.503220419655394
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	5/363	168/9376	0.768726223271678	PYGL/SLC25A6/HSP90AB1/PPIA/PARP1	-0.607019500859906
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/363	39/9376	0.662287207741753	HLA-G	-0.424111843933808
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	5/363	169/9376	0.764177547394331	RPS27A/UBA52/BNIP3/CTSL/VAMP8	-0.620831433542371
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/363	42/9376	0.614980978617342	ACAT2	-0.501853778019601
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/363	42/9376	0.614980978617342	GPX4	-0.501853778019601
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	2/363	78/9376	0.662287207741753	IMPA2/TPI1	-0.601041289019351
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/363	43/9376	0.600679095393683	ACAT2	-0.526683734533565
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	1/363	44/9376	0.587027297771099	CDK7	-0.551016474588451
Genetic Information Processing	Replication and repair	hsa03410	Base excision repair	1/363	44/9376	0.587027297771099	PARP1	-0.551016474588451
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/363	44/9376	0.587027297771099	GNAS	-0.551016474588451
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	5/363	178/9376	0.725539356795741	NOTUM/SERPINF1/RSPO3/RAC3/FRZB	-0.741903876837742
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/363	45/9376	0.573982246709519	ABCA7	-0.574875929845775
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/363	45/9376	0.573982246709519	HLA-G	-0.574875929845775
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	11/363	362/9376	0.784865226854177	COL1A2/RPS6/COL1A1/CCNE1/PGF/IGF2/YWHAE/COL4A1/HSP90AB1/ANGPT1/FLT1	-0.837742187617942
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	5/363	181/9376	0.713513842594706	FCGR2B/CEBPB/HSPD1/CALM3/CR1L	-0.781036496454125
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	3/363	117/9376	0.662287207741753	ACTB/MORF4L2/ACTG1	-0.73767092395923
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/363	46/9376	0.561504371781052	ALAS2	-0.598284328400724
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	1/363	46/9376	0.561504371781052	PSMA4	-0.598284328400724
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	6/363	216/9376	0.717477808386899	PPARG/HSPD1/CALM3/HSP90AB1/XBP1/CCL3L1	-0.843016297171431
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	2/363	86/9376	0.600679095393683	SLC2A1/GNAS	-0.746565093419875
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	2/363	87/9376	0.593774737975365	BIRC5/RAC3	-0.763917286237959
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/363	49/9376	0.527126553100579	GNAS	-0.666003090909253
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	4/363	155/9376	0.666560028436861	CCNE1/CYP11A1/HSD3B1/GNAS	-0.840037673557805
NA	NA	hsa04081	Hormone signaling	6/363	219/9376	0.707649345258312	CGA/LEP/DIO2/IGF2/GAST/GNAS	-0.878524315636572
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/363	51/9376	0.506454923567223	PLA2G2A	-0.70923760857617
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/363	52/9376	0.496715405806315	PLTP	-0.730328823746009
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	2/363	91/9376	0.567674749492931	FCGR2B/RAC3	-0.831657692844131
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/363	53/9376	0.487343417017516	GNAS	-0.75108812620064
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	6/363	227/9376	0.682710161284451	HLA-G/CALR/CALM3/RAC3/CCL3L1/GNAS	-0.971150513014428
Organismal Systems	Digestive system	hsa04970	Salivary secretion	2/363	93/9376	0.555466690364051	CALM3/GNAS	-0.86458137012559
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/363	94/9376	0.549557470253795	CEBPB/HSP90AB1	-0.880819252806768
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/363	55/9376	0.46962183821688	GM2A	-0.791662347324392
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	3/363	133/9376	0.582613558690114	PPP1CB/CALM3/GNAS	-0.972885982753467
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/363	97/9376	0.532560847462441	CALM3/GNAS	-0.928676874102028
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	2/363	98/9376	0.527126553100579	IMPA2/CALM3	-0.944354484143497
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	8/363	300/9376	0.688778696051423	PGF/IGF2/STMN1/DUSP9/ANGPT1/IL1RAP/RAC3/FLT1	-1.09947907125669
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	2/363	99/9376	0.5218020424632	MMP2/GNAS	-0.959899578614863
Human Diseases	Infectious disease: viral	hsa05162	Measles	3/363	136/9376	0.569761789013126	CCNE1/FCGR2B/EIF3H	-1.01425396174354
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/363	59/9376	0.43778306952421	CDH1	-0.869352971644338
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	5/363	205/9376	0.62998051468118	HLA-G/CCNE1/CALR/SKP2/CCNA2	-1.07497272144383
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/363	60/9376	0.43048668503214	RAC3	-0.888114646962187
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/363	60/9376	0.43048668503214	GNAS	-0.888114646962187
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	2/363	101/9376	0.511469328751057	CALM3/GNAS	-0.990603431348736
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	3/363	138/9376	0.561504371781052	ACTB/RAC3/ACTG1	-1.04140605215162
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/363	62/9376	0.416600017773038	CRYAB	-0.924907720573683
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/363	63/9376	0.409987319078228	ACAT2	-0.942955253195335
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	3/363	144/9376	0.538108356290174	SLC25A6/XBP1/PSMA4	-1.12092800245999
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/363	65/9376	0.397372324645052	AKR1B1	-0.978389656529378
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/363	65/9376	0.397372324645052	CGA	-0.978389656529378
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	6/363	250/9376	0.619900826446281	CTSL/CTSV/VAMP8/GM2A/ATP6V1B1/AP1M2	-1.22244959958688
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/363	66/9376	0.3913515318474	GATA3	-0.995790378627216
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	5/363	217/9376	0.595142882532912	MGST3/BIRC5/MGST1/HSP90AB1/GNAS	-1.21091004332331
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	6/363	253/9376	0.612550223761147	RPS27A/UBA52/ACTB/PFN1/BNIP3/ACTG1	-1.25375045244781
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/363	68/9376	0.379841192675417	CCNA2	-1.02999104780789
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/363	69/9376	0.374336247854034	RAC3	-1.04680297549822
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/363	70/9376	0.368988587170405	SLC2A1	-1.06343016514753
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/363	71/9376	0.363791564815893	CGA	-1.07987795076549
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	5/363	226/9376	0.571442502255052	CGA/PPP1CB/CALM3/RAC3/GNAS	-1.30875102657733
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/363	73/9376	0.353824672629156	CDH1	-1.11225548544718
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	4/363	193/9376	0.53532023009178	CXCL14/CCR7/RAC3/CCL3L1	-1.30901430678409
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	3/363	158/9376	0.490427869023957	RPS6/SKP2/ATP6V1B1	-1.29634359046112
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	4/363	195/9376	0.529829766193403	ACTB/SLC25A6/ACTG1/CR1L	-1.33147098818766
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	4/363	196/9376	0.527126553100579	HLA-G/RPS27A/UBA52/CALM3	-1.34262858176899
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	8/363	333/9376	0.620521347794075	HLA-G/COL1A2/COL1A1/CCNE1/COL4A1/CCNA2/GNAS/ATP6V1B1	-1.41500334315062
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	2/363	120/9376	0.43048668503214	YWHAE/CALM3	-1.26004802329237
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/363	76/9376	0.3398579092359	CALM3	-1.15959680841893
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/363	122/9376	0.423429526261121	IGFBP3/GNAS	-1.28638755908805
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/363	78/9376	0.331143603870877	CALM3	-1.19039112439327
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/363	78/9376	0.331143603870877	CR1L	-1.19039112439327
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	3/363	163/9376	0.475384069360645	CCNE1/BIRC5/CCNA2	-1.3559354217743
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/363	79/9376	0.326951912682638	ATP6V1B1	-1.2055701596466
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/363	80/9376	0.322865013774105	RPS6	-1.22060868191876
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	3/363	166/9376	0.466792790998706	PPP1CB/CALM3/SLC25A6	-1.39099159751507
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/363	83/9376	0.311195193999137	AURKB	-1.26491549155539
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	3/363	173/9376	0.447905221420723	ACTB/SLC25A6/ACTG1	-1.47087662264365
Organismal Systems	Sensory system	hsa04742	Taste transduction	1/363	86/9376	0.300339547696842	P2RY1	-1.3080759482173
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	2/363	133/9376	0.388409039126742	HLA-G/RAC3	-1.42555726330017
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/363	90/9376	0.28699112335476	PPARG	-1.3639740785106
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	3/363	180/9376	0.43048668503214	HLA-G/CALR/PPP1CB	-1.54826365357292
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/363	91/9376	0.283837374746466	GNAS	-1.37767145435289
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/363	93/9376	0.277733345182026	GATA3	-1.4047502863845
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	2/363	142/9376	0.363791564815893	FCGR2B/PPARG	-1.53303801825011
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	6/363	298/9376	0.520051028897887	LEP/CXCL14/EBI3/CCR7/IL1RAP/CCL3L1	-1.68971077305141
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/363	143/9376	0.361247567859138	SNRPD1/SNRPB	-1.54466189421096
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	2/363	144/9376	0.35873890419345	DLX5/DUSP9	-1.55622542422378
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/363	98/9376	0.263563276550289	FCGR2B	-1.47070495634237
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/363	99/9376	0.2609010212316	RAC3	-1.48361319217861
Human Diseases	Substance dependence	hsa05034	Alcoholism	3/363	191/9376	0.405694258145472	PPP1CB/CALM3/GNAS	-1.6652954470363
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	2/363	150/9376	0.344389348025712	CCNE1/CDH1	-1.6243857489757
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/363	103/9376	0.250768942737169	PPP1CB	-1.53436441993374
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/363	104/9376	0.248357702903157	PLA2G2A	-1.54684014405001
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/363	105/9376	0.245992391446937	PARP1	-1.55923420178833
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/363	105/9376	0.245992391446937	CALM3	-1.55923420178833
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	1/363	108/9376	0.2391592694623	RAN	-1.59594119216465
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/363	109/9376	0.236965147724114	CCL3L1	-1.60802319081903
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	6/363	323/9376	0.479799401274211	TPM1/CCNE1/EZR/STMN1/IGF2BP1/KIF23	-1.90932612015623
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/363	115/9376	0.224601748712421	GNAS	-1.67899367654134
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/363	116/9376	0.222665526740762	GNAS	-1.69057987482849
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	4/363	254/9376	0.406759072471313	CALM3/SLC25A6/GNAS/FLT1	-1.92356645484858
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/363	119/9376	0.217052110100238	CEBPB	-1.7249458733752
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/363	125/9376	0.206633608815427	RAC3	-1.79200299030176
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	2/363	183/9376	0.282286350840747	RAN/NHP2	-1.96767054958967
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	2/363	184/9376	0.280752185890526	ROBO2/RAC3	-1.97736443906053
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/363	187/9376	0.276248140127576	YWHAE/HSP90AB1	-2.00622960803267
NA	NA	hsa04082	Neuroactive ligand signaling	2/363	199/9376	0.259589960823401	P2RY1/GNAS	-2.11861838274165
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/363	144/9376	0.179369452096725	SCD	-1.99152284598756
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	3/363	250/9376	0.30995041322314	HLA-G/FOLR1/ARF4	-2.21929143692612
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/363	149/9376	0.173350342965962	GNAS	-2.04121442598272
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/363	168/9376	0.153745244654336	LEP	-2.22114736247717
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	4/363	370/9376	0.279234606507334	CGA/LEP/TMEM97/P2RY1	-2.83878879500865
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/363	449/9376	0.0575260603606423	CALM3	-4.10718266817816