category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	13/67	142/9376	12.8114357788522	CAV1/HSP90AB1/HSP90AA1/PECAM1/KLF2/DUSP1/FOS/HSP90B1/CALM1/ACTG1/ACTB/JUN/CDH5	12.0316019228348
Human Diseases	Infectious disease: viral	hsa05162	Measles	11/67	136/9376	11.3187006145742	FCGR2B/HSPA1A/MX1/OAS2/HSPA1B/OAS1/FOS/JUN/HSPA8/IRF7/MX2	10.2832407848716
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	13/67	216/9376	8.42233278054174	HSPA1A/HSP90AB1/HSP90AA1/HSPA1B/FOS/HSP90B1/CALM1/TNFSF10/ERO1A/HSPA5/JUN/HSPA8/IRF7	9.36248392833331
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	9/67	82/9376	15.3593010556971	B2M/HSPA1A/HSP90AB1/HSP90AA1/HSPA1B/HLA-B/HSPA5/HSPA8/HLA-E	11.0792514104187
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	10/67	173/9376	8.08903459580709	RSAD2/MX1/OAS2/OAS1/ACTG1/ACTB/TNFSF10/SOCS3/IRF7/MX2	7.98393441528293
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	10/67	174/9376	8.04254589123349	DNAJA1/HSPA1A/HSP90AB1/HSP90AA1/HSPA1B/HSP90B1/HSPH1/ERO1A/HSPA5/HSPA8	7.95489991154033
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	9/67	139/9376	9.06088263717384	HSPA1A/HSP90AB1/HSP90AA1/HSPA1B/FOS/HSP90B1/CALM1/JUN/HSPA8	8.12261840353341
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	9/67	156/9376	8.07347876004592	IFIT1/SCARB1/RSAD2/MX1/OAS2/OAS1/SOCS3/IRF7/MX2	7.55790479353754
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	10/67	248/9376	5.64275397207511	HSP90AB1/HSP90AA1/RHOB/FOS/HSP90B1/ACTG1/ACTB/TNFSF10/JUN/MYL12B	6.28615693903324
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	9/67	196/9376	6.42583003350594	FOS/ZFP36/CALM1/UBC/HLA-B/JUN/IRF7/HLA-E/GNG11	6.51245004004245
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	9/67	205/9376	6.14372042227885	B2M/ISG15/OAS2/OAS1/VIM/HLA-B/JUN/IRF7/HLA-E	6.31709580517709
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	7/67	116/9376	8.44467318579516	PECAM1/ACTG1/ACTB/MYL12B/CDH5/ITGB1/JAM3	6.8444832191476
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	8/67	180/9376	6.2195688225539	B2M/OAS2/OAS1/BST2/HLA-B/SOCS3/IRF7/HLA-E	5.99850360226137
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	6/67	94/9376	8.93235947919974	HSP90AB1/HSP90AA1/FOS/HSP90B1/JUN/JUND	6.5571792594285
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	8/67	203/9376	5.51488861113153	CAV1/FLT1/ACTG1/ACTB/JUN/MYL12B/ITGB1/COL4A1	5.51710039238981
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	7/67	155/9376	6.31988444872412	FCGR2B/SCARB1/ACTG1/HLA-B/ACTB/ITGB1/HLA-E	5.66566069206862
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	8/67	214/9376	5.23141302831636	B2M/FOS/BST2/CALM1/HLA-B/JUN/HLA-E/GNG11	5.31212989695216
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	5/67	70/9376	9.99573560767591	CAV1/ACTG1/HLA-B/ACTB/HLA-E	6.40878501072013
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	7/67	170/9376	5.76224758560141	ACTG1/ACTB/JUN/MYL12B/TJP1/ITGB1/JAM3	5.31584696887164
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	9/67	300/9376	4.19820895522388	HSPA1A/FLT1/HSPA1B/DUSP1/FOS/KIT/JUN/JUND/HSPA8	4.77630160659781
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	7/67	187/9376	5.23840689600128	HSP90AB1/HSP90AA1/OAS2/OAS1/JUN/TXNIP/IRF7	4.96661904408021
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	4/67	51/9376	10.9757096868598	ACTG1/ACTB/ERO1A/TJP1	6.06004702201899
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	6/67	142/9376	5.91297035947025	FCGR2B/FOS/JUNB/JUN/JUND/SOCS3	5.00454853504497
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	5/67	93/9376	7.52367196276681	ACTG1/ACTB/MYL12B/TJP1/CDH5	5.36365626924883
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	7/67	200/9376	4.89791044776119	FOS/ACTG1/ACTB/TNFSF10/JUN/TJP1/ITGB1	4.727066119575
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	6/67	154/9376	5.45221942236868	FOS/CALM1/KCNJ2/ACTG1/ACTB/JUN	4.72602359726246
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	7/67	217/9376	4.51420317766009	HSP90AB1/HSP90AA1/FOS/HSP90B1/KLF4/JUN/PTGES3	4.4432855974303
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	6/67	160/9376	5.24776119402985	PECAM1/HLA-B/CDH5/ITGB1/HLA-E/JAM3	4.59748557984464
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	7/67	224/9376	4.37313432835821	B2M/FOS/ZFP36/HLA-B/JUN/EGR1/HLA-E	4.3348209565931
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	7/67	238/9376	4.11589113257243	MX1/ISG15/OAS2/OAS1/FOS/JUN/MX2	4.13063386551794
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	4/67	76/9376	7.36527886881383	CALM1/KCNJ2/ACTG1/ACTB	4.72665910682542
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	4/67	78/9376	7.17642556448527	CAV1/ACTG1/ACTB/ITGB1	4.64687795831728
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	4/67	78/9376	7.17642556448527	FOS/CALM1/JUN/ITGB1	4.64687795831728
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	5/67	137/9376	5.10731016450594	FOS/ACTG1/ACTB/TNFSF10/JUN	4.10843882205682
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	5/67	138/9376	5.07030067056024	FOS/ACTG1/ACTB/JUN/ITGB1	4.08647249476926
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	6/67	212/9376	3.96057448606026	FLT1/CALM1/KIT/ACTG1/ACTB/ITGB1	3.69890269497262
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	4/67	91/9376	6.15122191241594	FCGR2B/FOS/IFITM1/JUN	4.18901124344322
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	8/67	362/9376	3.09260328193288	HSP90AB1/HSP90AA1/FLT1/HSP90B1/KIT/ITGB1/COL4A1/GNG11	3.44472006617434
NA	NA	hsa04518	Integrin signaling	5/67	154/9376	4.54351618530723	FLT1/ACTG1/ACTB/ITGB1/COL4A1	3.76143660505704
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	3/67	56/9376	7.49680170575693	HSPA1A/HSPA1B/HSPA8	4.13673016529894
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	4/67	109/9376	5.135423798439	HSP90AB1/HSP90AA1/FOS/JUN	3.68413227367628
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	4/67	112/9376	4.99786780383795	HSPA1A/HSPA1B/HSPA8/ITGB1	3.61085203133153
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	6/67	250/9376	3.3585671641791	CAV1/HSPA1A/HSPA1B/HLA-B/HSPA8/HLA-E	3.20663511825383
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	6/67	253/9376	3.31874225709398	UBC/ACTG1/ACTB/JUN/MYL12B/ITGB1	3.17187032838608
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	7/67	333/9376	2.94168795661333	MX1/ISG15/HLA-B/ITGB1/MX2/HLA-E/COL4A1	3.06067215604013
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	3/67	62/9376	6.77130476649013	HSPA1A/HSPA1B/HSPA8	3.86788239930093
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	4/67	119/9376	4.70387558008278	FOS/JUNB/JUN/SOCS3	3.44958032980069
Organismal Systems	Immune system	hsa04611	Platelet activation	4/67	126/9376	4.44254915896707	ACTG1/ACTB/MYL12B/ITGB1	3.30039622127253
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	3/67	69/9376	6.08436080467229	FOS/CALM1/JUN	3.59606534574985
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	6/67	275/9376	3.05324287652646	CAV1/HSPA1A/HSPA1B/HSPA5/HSPA8/EGR1	2.93179526366502
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	4/67	130/9376	4.30585533869116	FOS/JUN/COL4A1/GNG11	3.21995721676789
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	3/67	71/9376	5.91297035947025	JUN/TJP1/JAM3	3.52522347925823
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	5/67	204/9376	3.42990927714369	CAV1/ACTG1/ACTB/TIMP3/ITGB1	2.97676564074095
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	3/67	73/9376	5.75097117153956	MX1/BST2/MX2	3.45703549880585
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	4/67	140/9376	3.99829424307036	KLF2/CALM1/EGR1/GNG11	3.03226973314649
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	3/67	78/9376	5.38231917336395	FOS/JUN/ITGB1	3.29706918028944
NA	NA	hsa04517	IgSF CAM signaling	6/67	299/9376	2.80816652523337	ACTG1/ACTB/MYL12B/TJP1/ITGB1/JAM3	2.69571748568138
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	5/67	227/9376	3.08238542967979	B2M/CALM1/HLA-B/HLA-E/GNG11	2.69437943824188
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	3/67	86/9376	4.88163832002777	ACTG1/ACTB/ITGB1	3.06780647426478
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	5/67	233/9376	3.00301069758504	VIM/ACTG1/ACTB/ITGB1/COL4A1	2.62656645732138
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	4/67	157/9376	3.56535792375701	ZFP36L1/CALM1/HLA-B/HLA-E	2.74996654498607
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	3/67	93/9376	4.51420317766009	CALM1/JUN/EGR1	2.88932031114521
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	3/67	95/9376	4.4191673212883	FLT1/FOS/JUN	2.84155649363538
Human Diseases	Immune disease	hsa05330	Allograft rejection	2/67	39/9376	7.17642556448527	HLA-B/HLA-E	3.27896937438829
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	3/67	97/9376	4.32805046930297	FOS/CALM1/GNG11	2.7950958657378
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	3/67	99/9376	4.24061510628675	ACTG1/ACTB/ITGB1	2.74987400482617
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	3/67	101/9376	4.15664252992463	JUN/EGR1/COL4A1	2.70583092281045
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	3/67	105/9376	3.99829424307036	ACTG1/ACTB/ITGB1	2.6210610354379
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	2/67	44/9376	6.36092265943012	HLA-B/HLA-E	3.02377895020134
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	3/67	106/9376	3.96057448606026	HSP90AB1/HSP90AA1/HSP90B1	2.60052229869236
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	2/67	45/9376	6.2195688225539	HLA-B/HLA-E	2.97747631115471
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	3/67	109/9376	3.85156784882925	FOS/JUN/IRF7	2.54038126549811
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	3/67	115/9376	3.65061648280337	FOS/KCNJ2/GNG11	2.42626591289157
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	3/67	115/9376	3.65061648280337	FOS/JUND/EGR1	2.42626591289157
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	3/67	122/9376	3.44115488133105	FOS/JUNB/SOCS3	2.30240662720998
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	2/67	54/9376	5.18297401879491	HLA-B/HLA-E	2.61516455968707
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	4/67	205/9376	2.73054240990171	HLA-B/JUN/IRF7/HLA-E	2.12531033975363
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/67	59/9376	4.74373893245636	FABP4/MGLL	2.44717506202062
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	3/67	133/9376	3.1565480866345	HLA-B/TNFSF10/HLA-E	2.12495635715218
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	3/67	133/9376	3.1565480866345	FOS/CALM1/GNG11	2.12495635715218
Genetic Information Processing	Information processing in viruses	hsa03265	Virion - Ebolavirus, Lyssavirus and Morbillivirus	1/67	12/9376	11.6616915422886	FCGR2B	3.13514447188716
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	4/67	232/9376	2.41276376737005	ACTG1/ACTB/MYL12B/ITGB1	1.84848936528479
Organismal Systems	Endocrine system	hsa04924	Renin secretion	2/67	69/9376	4.05624053644819	CALM1/KCNJ2	2.16161698660283
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	3/67	148/9376	2.83662767244857	FOS/KIT/JUN	1.91059973296998
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	2/67	70/9376	3.99829424307036	EPAS1/JUN	2.13605913298759
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	4/67	238/9376	2.35193779004139	FLT1/CALM1/KIT/GNG11	1.79221923424779
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/67	71/9376	3.94198023964684	FOS/SOCS3	2.11097097223991
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	2/67	72/9376	3.88723051409619	ISG15/IRF7	2.08633661875151
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	2/67	75/9376	3.73174129353234	HSP90B1/HSPA5	2.01500858820864
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	3/67	157/9376	2.67401844281776	FOS/JUN/SOCS3	1.79448437615934
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	2/67	76/9376	3.68263943440691	FABP4/UBC	1.99204502650979
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	3/67	163/9376	2.57558831608827	FOS/JUN/IRF7	1.72150204370481
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	3/67	168/9376	2.49893390191898	HSP90AB1/HSP90AA1/TNFSF10	1.66312921381839
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	4/67	268/9376	2.08866117175317	DUSP1/CALM1/UBC/HSPA5	1.53398157794154
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	2/67	87/9376	3.2170183564934	FOS/JUN	1.76244656351165
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	2/67	89/9376	3.14472580915646	ITGB1/COL4A1	1.72464845212546
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	2/67	90/9376	3.10978441127695	FOS/JUN	1.70614728172006
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	2/67	93/9376	3.00946878510672	FOS/JUN	1.6521523320934
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	2/67	93/9376	3.00946878510672	ITGB1/COL4A1	1.6521523320934
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	2/67	98/9376	2.85592445933597	SCARB1/CALM1	1.56681483010379
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	2/67	99/9376	2.8270767375245	FOS/JUN	1.55039418769427
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/67	99/9376	2.8270767375245	FOS/JUN	1.55039418769427
Cellular Processes	Cell motility	hsa04814	Motor proteins	3/67	194/9376	2.16402523465148	ACTG1/ACTB/MYL12B	1.38984426877256
NA	NA	hsa04519	Cadherin signaling	5/67	404/9376	1.7319343874686	VIM/ACTG1/ACTB/TJP1/CDH5	1.27582094019283
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	2/67	101/9376	2.77109501994976	CALM1/KIT	1.51815849491518
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/67	103/9376	2.71728734965947	FOS/JUN	1.48669875444613
Organismal Systems	Digestive system	hsa04977	Vitamin digestion and absorption	1/67	26/9376	5.38231917336395	SCARB1	1.89826306609349
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	2/67	105/9376	2.66552949538024	UBC/JUN	1.45597933685232
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	2/67	105/9376	2.66552949538024	CALM1/JUN	1.45597933685232
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	2/67	110/9376	2.54436906377205	FLT1/EPAS1	1.38220612284025
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	2/67	110/9376	2.54436906377205	HSP90AB1/HSP90AA1	1.38220612284025
Organismal Systems	Sensory system	hsa04744	Phototransduction	1/67	29/9376	4.82552753474009	CALM1	1.75035336657086
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/67	115/9376	2.43374432186892	DUSP1/GNG11	1.31239090925492
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	1/67	31/9376	4.51420317766009	HSPA5	1.66260692692967
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	2/67	117/9376	2.39214185482842	ACTG1/ACTB	1.28548171637606
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	2/67	120/9376	2.33233830845771	CALM1/JUN	1.2461347003085
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	2/67	122/9376	2.2941032542207	FOS/JUN	1.22055013043135
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/67	122/9376	2.2941032542207	ACTG1/ACTB	1.22055013043135
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	3/67	226/9376	1.85761458195747	FOS/CALM1/JUN	1.10715226695954
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	3/67	235/9376	1.78647189583995	MGLL/ACTG1/ACTB	1.0358379280382
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/67	38/9376	3.68263943440691	SCNN1B	1.40571957415201
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	2/67	133/9376	2.10436539108966	KLF2/TNFSF10	1.08818730867121
Genetic Information Processing	Transcription	hsa03040	Spliceosome	3/67	243/9376	1.72765800626497	HSPA1A/HSPA1B/HSPA8	0.974978961763282
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	2/67	138/9376	2.0281202682241	CALM1/SOCS3	1.03220512130724
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/67	43/9376	3.25442554668518	SCARB1	1.25698766641738
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	2/67	142/9376	1.97099011982342	UBC/SOCS3	0.989089456307935
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/67	47/9376	2.97745315973325	SOCS3	1.15294638491979
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	2/67	149/9376	1.87839326855655	MGLL/GNG11	0.916903007537065
NA	NA	hsa03272	Virion - Hepatitis viruses	1/67	48/9376	2.91542288557214	SCARB1	1.12865847359359
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/67	49/9376	2.85592445933597	JUN	1.10499133244229
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/67	50/9376	2.79880597014925	AMD1	1.0819149982091
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/67	50/9376	2.79880597014925	PECAM1	1.0819149982091
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	2/67	157/9376	1.78267896187851	PECAM1/SLC16A1	0.839002207332604
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	2/67	157/9376	1.78267896187851	ACTG1/ACTB	0.839002207332604
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/67	52/9376	2.69115958668197	SCARB1	1.03742487138676
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/67	52/9376	2.69115958668197	SCARB1	1.03742487138676
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/67	54/9376	2.59148700939746	AMD1	0.994985961059741
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	2/67	170/9376	1.64635645302897	ACTG1/ACTB	0.721493775761089
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/67	59/9376	2.37186946622818	CMPK2	0.896751831970932
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/67	63/9376	2.22127457948353	PTGES3	0.825107082715105
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/67	181/9376	1.54630164096644	FCGR2B/CALM1	0.629603958777844
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/67	65/9376	2.15292766934558	MGLL	0.791283484693026
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/67	65/9376	2.15292766934558	SCARB1	0.791283484693026
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/67	66/9376	2.12030755314337	JUN	0.774829086937305
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	2/67	184/9376	1.52109020116807	MYL12B/ITGB1	0.605603441684411
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/67	67/9376	2.08866117175317	CALM1	0.758665166470085
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/67	68/9376	2.05794556628622	KIT	0.742781564612189
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/67	70/9376	1.99914712153518	SOCS3	0.711817173743411
Human Diseases	Substance dependence	hsa05034	Alcoholism	2/67	191/9376	1.46534343986872	CALM1/GNG11	0.551216518272727
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/67	71/9376	1.97099011982342	KIT	0.69671846522159
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/67	195/9376	1.43528511289705	ACTG1/ACTB	0.52109589332381
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/67	76/9376	1.84131971720346	CALM1	0.624737986351972
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/67	78/9376	1.79410639112132	BTG2	0.597451624233742
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/67	83/9376	1.686027692861	IRF7	0.532566996231744
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/67	85/9376	1.64635645302897	CMPK2	0.507834084522615
NA	NA	hsa04382	Cornified envelope formation	2/67	217/9376	1.28977233647431	TJP1/COL4A1	0.366382131054623
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/67	86/9376	1.62721277334259	JUN	0.49571012241764
Organismal Systems	Sensory system	hsa04742	Taste transduction	1/67	86/9376	1.62721277334259	SCNN1B	0.49571012241764
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	1/67	88/9376	1.59023066485753	A2M	0.471925588648215
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/67	89/9376	1.57236290457823	TJP1	0.460256874431479
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	1/67	89/9376	1.57236290457823	GNG11	0.460256874431479
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/67	90/9376	1.55489220563847	SCARB1	0.448732023631137
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/67	91/9376	1.53780547810399	GNG11	0.437347338722269
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	2/67	227/9376	1.23295417187192	FOS/JUN	0.301417269732278
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/67	93/9376	1.50473439255336	CALM1	0.41498435304159
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	3/67	368/9376	1.14081765087605	ACTG1/ACTB/HSPA5	0.23379668020754
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/67	98/9376	1.42796222966799	CALM1	0.361295722352834
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/67	98/9376	1.42796222966799	FCGR2B	0.361295722352834
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/67	99/9376	1.41353836876225	CALM1	0.350914370562372
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/67	99/9376	1.41353836876225	FCGR2B	0.350914370562372
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/67	100/9376	1.39940298507463	TNFSF10	0.340645346750874
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	1/67	100/9376	1.39940298507463	KIT	0.340645346750874
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	1/67	103/9376	1.35864367482973	COL4A1	0.310486829571696
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	1/67	103/9376	1.35864367482973	COL4A1	0.310486829571696
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/67	107/9376	1.30785325707909	CALM1	0.271700679740801
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/67	109/9376	1.28385594960975	SOCS3	0.252879249141781
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/67	254/9376	1.10189211423199	FLT1/CALM1	0.139663821977412
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/67	116/9376	1.20638188368502	GNG11	0.189743364734061
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/67	134/9376	1.04433058587659	CALM1	0.0438474571650226
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/67	138/9376	1.01406013411205	CALM1	0.014115996819897
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/67	144/9376	0.971807628524046	KLF4	-0.0289225434231423
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/67	149/9376	0.939196634278273	KIT	-0.0634690529792448
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/67	154/9376	0.908703237061446	CMPK2	-0.0969113637646662
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/67	154/9376	0.908703237061446	CALM1	-0.0969113637646662
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/67	155/9376	0.902840635532017	SCARB1	-0.103474426453875
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	3/67	480/9376	0.874626865671642	CALM1/UBC/HSPA5	-0.239220965752574
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	2/67	323/9376	0.866503396331038	VIM/TIMP3	-0.207131782319368
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/67	166/9376	0.843013846430498	CALM1	-0.173123929883527
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/67	168/9376	0.832977967306325	SOCS3	-0.185317859292234
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/67	169/9376	0.828049103594454	UBC	-0.191364003991972
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/67	178/9376	0.786181452289116	JUN	-0.244331914710183
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/67	193/9376	0.725079266878045	GNG11	-0.327389977519028
NA	NA	hsa04082	Neuroactive ligand signaling	1/67	199/9376	0.703217580439511	GNG11	-0.358992907046116
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/67	201/9376	0.696220390584391	FLT1	-0.369338971968827
NA	NA	hsa04081	Hormone signaling	1/67	219/9376	0.638996796837729	GNG11	-0.458593642842041
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/67	298/9376	0.469598317139137	TNFSF10	-0.789386074122858
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	1/67	388/9376	0.360670872441914	CALM1	-1.09113967249733
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/67	449/9376	0.311671043446465	CALM1	-1.26805463933493