ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0051082 unfolded protein binding 15/433 121/18639 0.12396694214876 5.33630446815414 1.38830987939227e-07 0.000107177522689083 GO:0042605 peptide antigen binding 9/433 45/18639 0.2 8.60923787528868 7.65598080798128e-07 0.000295520859188077 GO:0044183 protein folding chaperone 11/433 75/18639 0.146666666666667 6.31344110854503 1.2054991375236e-06 0.000310215111389406 GO:0031072 heat shock protein binding 13/433 131/18639 0.099236641221374 4.27175925109744 1.16118734123605e-05 0.00224109156858558 GO:0051087 protein-folding chaperone binding 13/433 134/18639 0.0970149253731343 4.17612284995347 1.48461298418665e-05 0.00229224244758419 GO:0140662 ATP-dependent protein folding chaperone 7/433 40/18639 0.175 7.5330831408776 3.34221784442673e-05 0.0043003202931624 GO:0003725 double-stranded RNA binding 9/433 75/18639 0.12 5.16554272517321 5.8657032374731e-05 0.00646903271332747 GO:0140375 immune receptor activity 12/433 156/18639 0.0769230769230769 3.31124533664949 0.000293026093917941 0.0282770180630813 GO:0023026 MHC class II protein complex binding 5/433 27/18639 0.185185185185185 7.97151655119323 0.000349872721847295 0.0300113045851235 GO:0051879 Hsp90 protein binding 6/433 42/18639 0.142857142857143 6.1494556252062 0.00039212065767254 0.0302717147723201 GO:0140297 DNA-binding transcription factor binding 24/433 488/18639 0.0491803278688525 2.1170257070382 0.000488703190790511 0.0342980784809341 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 19/433 349/18639 0.0544412607449857 2.34348881992099 0.000558456316705684 0.0359273563747323 GO:0051059 NF-kappaB binding 5/433 32/18639 0.15625 6.72596709006928 0.000793349459660236 0.0459916033995501 GO:0001217 DNA-binding transcription repressor activity 16/433 278/18639 0.0575539568345324 2.47747852526293 0.000834044621235365 0.0459916033995501 GO:0060590 ATPase regulator activity 6/433 49/18639 0.122448979591837 5.27096196446246 0.000911767542650002 0.0469256361950535 GO:0000175 3'-5'-RNA exonuclease activity 5/433 35/18639 0.142857142857143 6.1494556252062 0.00120796777824224 0.058284445300188 GO:0044389 ubiquitin-like protein ligase binding 17/433 322/18639 0.0527950310559006 2.27262490496751 0.0014951000133032 0.0642397499942995 GO:0023023 MHC protein complex binding 5/433 37/18639 0.135135135135135 5.8170526184383 0.00156150711829442 0.0642397499942995 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 15/433 268/18639 0.0559701492537313 2.40930164420392 0.00158103011644001 0.0642397499942995 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 5/433 38/18639 0.131578947368421 5.66397228637413 0.00176428645993917 0.068101457353652 GO:0031625 ubiquitin protein ligase binding 16/433 302/18639 0.0529801324503311 2.28059281464601 0.0019655817612258 0.0722585295079198 GO:0042277 peptide binding 14/433 249/18639 0.0562248995983936 2.42026767578397 0.00214497231794826 0.0747415582439039 GO:0004532 RNA exonuclease activity 5/433 40/18639 0.125 5.38077367205543 0.0022267562689246 0.0747415582439039 GO:0004197 cysteine-type endopeptidase activity 7/433 88/18639 0.0795454545454545 3.42412870039891 0.00439000113796044 0.132862440497499 GO:0000774 adenyl-nucleotide exchange factor activity 3/433 15/18639 0.2 8.60923787528868 0.00460113824382138 0.132862440497499 GO:0050700 CARD domain binding 3/433 15/18639 0.2 8.60923787528868 0.00460113824382138 0.132862440497499 GO:0016922 nuclear receptor binding 9/433 137/18639 0.0656934306569343 2.82785185684665 0.00475595144146635 0.132862440497499 GO:0003924 GTPase activity 16/433 331/18639 0.0483383685800604 2.0807825680456 0.00481884499213727 0.132862440497499 GO:0030544 Hsp70 protein binding 5/433 51/18639 0.0980392156862745 4.22021464474935 0.00645792347956405 0.16545400138534 GO:0051787 misfolded protein binding 3/433 17/18639 0.176470588235294 7.59638636054884 0.00664387829397092 0.16545400138534 GO:1990226 histone methyltransferase binding 3/433 17/18639 0.176470588235294 7.59638636054884 0.00664387829397092 0.16545400138534 GO:0140296 general transcription initiation factor binding 5/433 53/18639 0.0943396226415094 4.06096126192862 0.00759788917903241 0.183299076444157 GO:0046332 SMAD binding 6/433 79/18639 0.0759493670886076 3.26933083871722 0.010141580361013 0.237251516324304 GO:0008408 3'-5' exonuclease activity 5/433 58/18639 0.0862068965517241 3.71087839452098 0.0110450615673802 0.250787868529926 GO:0045296 cadherin binding 15/433 334/18639 0.0449101796407186 1.93321209774446 0.0117896432799457 0.255909849055929 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/433 21/18639 0.142857142857143 6.1494556252062 0.0121336639209698 0.255909849055929 GO:0008234 cysteine-type peptidase activity 10/433 187/18639 0.053475935828877 2.30193526077238 0.0122651093459448 0.255909849055929 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 5/433 60/18639 0.0833333333333333 3.58718244803695 0.0126809021464741 0.257622538344158 GO:0005525 GTP binding 16/433 378/18639 0.0423280423280423 1.82206092598702 0.0158850817325445 0.314443156346778 GO:0019207 kinase regulator activity 13/433 287/18639 0.0452961672473868 1.94982739335806 0.0171655995805017 0.326243934270686 GO:0001046 core promoter sequence-specific DNA binding 4/433 44/18639 0.0909090909090909 3.91328994331304 0.0187563425898905 0.326243934270686 GO:0016829 lyase activity 10/433 200/18639 0.05 2.15230946882217 0.01879138993787 0.326243934270686 GO:0017025 TBP-class protein binding 3/433 25/18639 0.12 5.16554272517321 0.0195994599984376 0.326243934270686 GO:0140303 intramembrane lipid transporter activity 4/433 45/18639 0.0888888888888889 3.82632794457275 0.0202192799826275 0.326243934270686 GO:0003823 antigen binding 9/433 174/18639 0.0517241379310345 2.22652703671259 0.0206707334315053 0.326243934270686 GO:0005528 FK506 binding 2/433 10/18639 0.2 8.60923787528868 0.0214164323606891 0.326243934270686 GO:0008140 cAMP response element binding protein binding 2/433 10/18639 0.2 8.60923787528868 0.0214164323606891 0.326243934270686 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/433 10/18639 0.2 8.60923787528868 0.0214164323606891 0.326243934270686 GO:0032395 MHC class II receptor activity 2/433 10/18639 0.2 8.60923787528868 0.0214164323606891 0.326243934270686 GO:1905394 retromer complex binding 2/433 10/18639 0.2 8.60923787528868 0.0214164323606891 0.326243934270686 GO:0070412 R-SMAD binding 3/433 26/18639 0.115384615384615 4.96686800497424 0.0217824669684804 0.326243934270686 GO:0032182 ubiquitin-like protein binding 7/433 120/18639 0.0583333333333333 2.51102771362587 0.0220167344614648 0.326243934270686 GO:0004540 RNA nuclease activity 7/433 121/18639 0.0578512396694215 2.49027541847193 0.0229198566790943 0.326243934270686 GO:0001671 ATPase activator activity 3/433 27/18639 0.111111111111111 4.78290993071594 0.0240927563924123 0.326243934270686 GO:0004896 cytokine receptor activity 6/433 96/18639 0.0625 2.69038683602771 0.0244380767787136 0.326243934270686 GO:0019001 guanyl nucleotide binding 16/433 400/18639 0.04 1.72184757505774 0.0253528007957546 0.326243934270686 GO:0032561 guanyl ribonucleotide binding 16/433 400/18639 0.04 1.72184757505774 0.0253528007957546 0.326243934270686 GO:0019864 IgG binding 2/433 11/18639 0.181818181818182 7.82657988662608 0.0257783419566216 0.326243934270686 GO:0031731 CCR6 chemokine receptor binding 2/433 11/18639 0.181818181818182 7.82657988662608 0.0257783419566216 0.326243934270686 GO:0034511 U3 snoRNA binding 2/433 11/18639 0.181818181818182 7.82657988662608 0.0257783419566216 0.326243934270686 GO:0042608 T cell receptor binding 2/433 11/18639 0.181818181818182 7.82657988662608 0.0257783419566216 0.326243934270686 GO:0051019 mitogen-activated protein kinase binding 3/433 28/18639 0.107142857142857 4.61209171890465 0.0265302234507835 0.330344072645239 GO:0043130 ubiquitin binding 6/433 100/18639 0.06 2.5827713625866 0.0291233620025561 0.345607704859335 GO:0019003 GDP binding 5/433 75/18639 0.0666666666666667 2.86974595842956 0.0303101202858741 0.345607704859335 GO:0004859 phospholipase inhibitor activity 2/433 12/18639 0.166666666666667 7.1743648960739 0.0304654278385682 0.345607704859335 GO:0005095 GTPase inhibitor activity 2/433 12/18639 0.166666666666667 7.1743648960739 0.0304654278385682 0.345607704859335 GO:0005527 macrolide binding 2/433 12/18639 0.166666666666667 7.1743648960739 0.0304654278385682 0.345607704859335 GO:0016840 carbon-nitrogen lyase activity 2/433 12/18639 0.166666666666667 7.1743648960739 0.0304654278385682 0.345607704859335 GO:0001968 fibronectin binding 3/433 30/18639 0.1 4.30461893764434 0.0317851645660787 0.345607704859335 GO:0031624 ubiquitin conjugating enzyme binding 3/433 30/18639 0.1 4.30461893764434 0.0317851645660787 0.345607704859335 GO:0070566 adenylyltransferase activity 3/433 30/18639 0.1 4.30461893764434 0.0317851645660787 0.345607704859335 GO:0016251 RNA polymerase II general transcription initiation factor activity 4/433 53/18639 0.0754716981132075 3.2487690095429 0.0344327826639892 0.369195947452774 GO:0004535 poly(A)-specific ribonuclease activity 2/433 13/18639 0.153846153846154 6.62249067329899 0.0354603012456694 0.369937196779146 GO:0032396 inhibitory MHC class I receptor activity 2/433 13/18639 0.153846153846154 6.62249067329899 0.0354603012456694 0.369937196779146 GO:0061630 ubiquitin protein ligase activity 14/433 353/18639 0.0396600566572238 1.70721430954733 0.0371407706394853 0.382302332449102 GO:0140313 molecular sequestering activity 4/433 55/18639 0.0727272727272727 3.13063195465043 0.0386993700896836 0.390202211146356 GO:0016779 nucleotidyltransferase activity 7/433 136/18639 0.0514705882352941 2.21561268849341 0.0396507410900059 0.390202211146356 GO:0019239 deaminase activity 3/433 33/18639 0.0909090909090909 3.91328994331304 0.0406066369070141 0.390202211146356 GO:0140311 protein sequestering activity 3/433 33/18639 0.0909090909090909 3.91328994331304 0.0406066369070141 0.390202211146356 GO:0019763 immunoglobulin receptor activity 2/433 14/18639 0.142857142857143 6.1494556252062 0.0407462025903341 0.390202211146356 GO:0030170 pyridoxal phosphate binding 4/433 56/18639 0.0714285714285714 3.0747278126031 0.0409409055736462 0.390202211146356 GO:0070279 vitamin B6 binding 4/433 57/18639 0.0701754385964912 3.02078521939954 0.0432546441091184 0.406967156955272 GO:0070851 growth factor receptor binding 7/433 139/18639 0.0503597122302158 2.16779370960506 0.0437542409679891 0.406967156955272 GO:0004527 exonuclease activity 5/433 84/18639 0.0595238095238095 2.56227317716925 0.0459183339739599 0.41568592893346 GO:0031386 protein tag activity 2/433 15/18639 0.133333333333333 5.73949191685912 0.0463069817205668 0.41568592893346 GO:0141047 molecular tag activity 2/433 15/18639 0.133333333333333 5.73949191685912 0.0463069817205668 0.41568592893346 GO:0001786 phosphatidylserine binding 4/433 59/18639 0.0677966101694915 2.91838572043684 0.048098483379399 0.421954876919273 GO:0070888 E-box binding 4/433 59/18639 0.0677966101694915 2.91838572043684 0.048098483379399 0.421954876919273 GO:0044390 ubiquitin-like protein conjugating enzyme binding 3/433 36/18639 0.0833333333333333 3.58718244803695 0.0505280453760135 0.425961154324419 GO:0001221 transcription coregulator binding 6/433 115/18639 0.0521739130434783 2.24588814137966 0.0517727209255169 0.425961154324419 GO:0004175 endopeptidase activity 15/433 405/18639 0.037037037037037 1.59430331023865 0.0521137155095121 0.425961154324419 GO:0055102 lipase inhibitor activity 2/433 16/18639 0.125 5.38077367205543 0.0521270787564378 0.425961154324419 GO:0140328 floppase activity 2/433 16/18639 0.125 5.38077367205543 0.0521270787564378 0.425961154324419 GO:0015026 coreceptor activity 4/433 61/18639 0.0655737704918033 2.8227009427176 0.0532297969653896 0.425961154324419 GO:0061659 ubiquitin-like protein ligase activity 14/433 372/18639 0.0376344086021505 1.62001787975862 0.0532307845519424 0.425961154324419 GO:0042805 actinin binding 3/433 37/18639 0.0810810810810811 3.49023157106298 0.0540727890204573 0.425961154324419 GO:0043394 proteoglycan binding 3/433 37/18639 0.0810810810810811 3.49023157106298 0.0540727890204573 0.425961154324419 GO:0070001 aspartic-type peptidase activity 3/433 37/18639 0.0810810810810811 3.49023157106298 0.0540727890204573 0.425961154324419 GO:0019209 kinase activator activity 7/433 148/18639 0.0472972972972973 2.03596841645341 0.0576663651189675 0.444790517170692 GO:0008429 phosphatidylethanolamine binding 2/433 17/18639 0.117647058823529 5.06425757369923 0.0581915054847667 0.444790517170692 GO:0036041 long-chain fatty acid binding 2/433 17/18639 0.117647058823529 5.06425757369923 0.0581915054847667 0.444790517170692 GO:0004842 ubiquitin-protein transferase activity 16/433 449/18639 0.0356347438752784 1.53393993323629 0.0607448708730227 0.453475620069879 GO:0072341 modified amino acid binding 5/433 91/18639 0.0549450549450549 2.36517524046392 0.0608335472813225 0.453475620069879 GO:0019842 vitamin binding 7/433 150/18639 0.0466666666666667 2.00882217090069 0.0610899799057868 0.453475620069879 GO:0004706 JUN kinase kinase kinase activity 2/433 18/18639 0.111111111111111 4.78290993071594 0.0644858272965201 0.455855047616972 GO:0016854 racemase and epimerase activity 2/433 18/18639 0.111111111111111 4.78290993071594 0.0644858272965201 0.455855047616972 GO:0017128 phospholipid scramblase activity 2/433 18/18639 0.111111111111111 4.78290993071594 0.0644858272965201 0.455855047616972 GO:0032393 MHC class I receptor activity 2/433 18/18639 0.111111111111111 4.78290993071594 0.0644858272965201 0.455855047616972 GO:0034185 apolipoprotein binding 2/433 18/18639 0.111111111111111 4.78290993071594 0.0644858272965201 0.455855047616972 GO:0015036 disulfide oxidoreductase activity 3/433 40/18639 0.075 3.22846420323326 0.0653949731151904 0.455855047616972 GO:0051219 phosphoprotein binding 5/433 93/18639 0.0537634408602151 2.31431125679803 0.0655439252402641 0.455855047616972 GO:0016755 aminoacyltransferase activity 17/433 496/18639 0.0342741935483871 1.47537342620875 0.0722964958178986 0.489130584146711 GO:0005548 phospholipid transporter activity 4/433 68/18639 0.0588235294117647 2.53212878684961 0.0734165146431552 0.489130584146711 GO:0140223 general transcription initiation factor activity 4/433 68/18639 0.0588235294117647 2.53212878684961 0.0734165146431552 0.489130584146711 GO:1990841 promoter-specific chromatin binding 4/433 68/18639 0.0588235294117647 2.53212878684961 0.0734165146431552 0.489130584146711 GO:0048487 beta-tubulin binding 3/433 42/18639 0.0714285714285714 3.0747278126031 0.0734963053899203 0.489130584146711 GO:0019887 protein kinase regulator activity 10/433 255/18639 0.0392156862745098 1.68808585789974 0.0749969832073303 0.494851889197086 GO:0048156 tau protein binding 3/433 43/18639 0.0697674418604651 3.00322251463559 0.077706456413134 0.507444744035898 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 6/433 128/18639 0.046875 2.01779012702079 0.0782201095081242 0.507444744035898 GO:0097110 scaffold protein binding 4/433 70/18639 0.0571428571428571 2.45978225008248 0.0798044977899765 0.513408935782182 GO:0035591 signaling adaptor activity 6/433 129/18639 0.0465116279069767 2.00214834309039 0.0805197129821408 0.513729077869527 GO:0001223 transcription coactivator binding 3/433 44/18639 0.0681818181818182 2.93496745748478 0.0820198793758104 0.514791438033542 GO:0030547 signaling receptor inhibitor activity 3/433 44/18639 0.0681818181818182 2.93496745748478 0.0820198793758104 0.514791438033542 GO:0019200 carbohydrate kinase activity 2/433 21/18639 0.0952380952380952 4.0996370834708 0.0846117565461189 0.52256220842883 GO:0070182 DNA polymerase binding 2/433 21/18639 0.0952380952380952 4.0996370834708 0.0846117565461189 0.52256220842883 GO:0004715 non-membrane spanning protein tyrosine kinase activity 3/433 45/18639 0.0666666666666667 2.86974595842956 0.0864342079038948 0.525561181378389 GO:0005518 collagen binding 4/433 72/18639 0.0555555555555556 2.39145496535797 0.0864588990091391 0.525561181378389 GO:0043539 protein serine/threonine kinase activator activity 4/433 73/18639 0.0547945205479452 2.35869530829827 0.0898841121540021 0.542113551428825 GO:0033691 sialic acid binding 2/433 22/18639 0.0909090909090909 3.91328994331304 0.0916917816324526 0.544508118617334 GO:0050321 tau-protein kinase activity 2/433 22/18639 0.0909090909090909 3.91328994331304 0.0916917816324526 0.544508118617334 GO:0019787 ubiquitin-like protein transferase activity 16/433 479/18639 0.0334029227557411 1.43786853867034 0.0942222306536691 0.555263832554447 GO:0004602 glutathione peroxidase activity 2/433 23/18639 0.0869565217391304 3.74314690229943 0.098937236751152 0.561614314499186 GO:0005158 insulin receptor binding 2/433 23/18639 0.0869565217391304 3.74314690229943 0.098937236751152 0.561614314499186 GO:0005212 structural constituent of eye lens 2/433 23/18639 0.0869565217391304 3.74314690229943 0.098937236751152 0.561614314499186 GO:0016493 C-C chemokine receptor activity 2/433 23/18639 0.0869565217391304 3.74314690229943 0.098937236751152 0.561614314499186 GO:0031681 G-protein beta-subunit binding 2/433 23/18639 0.0869565217391304 3.74314690229943 0.098937236751152 0.561614314499186 GO:0005096 GTPase activator activity 10/433 271/18639 0.03690036900369 1.58842027219348 0.101688111262588 0.561926545342194 GO:0030295 protein kinase activator activity 6/433 139/18639 0.0431654676258993 1.8581088939472 0.105554941243586 0.561926545342194 GO:0019957 C-C chemokine binding 2/433 24/18639 0.0833333333333333 3.58718244803695 0.106336658144947 0.561926545342194 GO:0030215 semaphorin receptor binding 2/433 24/18639 0.0833333333333333 3.58718244803695 0.106336658144947 0.561926545342194 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/433 24/18639 0.0833333333333333 3.58718244803695 0.106336658144947 0.561926545342194 GO:0004843 cysteine-type deubiquitinase activity 5/433 108/18639 0.0462962962962963 1.99287913779831 0.107062595869674 0.561926545342194 GO:0005126 cytokine receptor binding 10/433 275/18639 0.0363636363636364 1.56531597732522 0.109127129327409 0.561926545342194 GO:0048020 CCR chemokine receptor binding 3/433 50/18639 0.06 2.5827713625866 0.109933151013713 0.561926545342194 GO:0004709 MAP kinase kinase kinase activity 2/433 25/18639 0.08 3.44369515011547 0.113879023201165 0.561926545342194 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/433 25/18639 0.08 3.44369515011547 0.113879023201165 0.561926545342194 GO:0120020 cholesterol transfer activity 2/433 25/18639 0.08 3.44369515011547 0.113879023201165 0.561926545342194 GO:0016830 carbon-carbon lyase activity 3/433 51/18639 0.0588235294117647 2.53212878684961 0.114900598766585 0.561926545342194 GO:0004518 nuclease activity 8/433 209/18639 0.0382775119617225 1.64770102876338 0.115013176977763 0.561926545342194 GO:0140098 catalytic activity, acting on RNA 13/433 387/18639 0.0335917312661499 1.44599602556528 0.118651775067634 0.561926545342194 GO:0030246 carbohydrate binding 10/433 280/18639 0.0357142857142857 1.53736390630155 0.118851167883009 0.561926545342194 GO:0001618 virus receptor activity 4/433 81/18639 0.0493827160493827 2.12573774698486 0.119523184636475 0.561926545342194 GO:0033192 calmodulin-dependent protein phosphatase activity 4/433 81/18639 0.0493827160493827 2.12573774698486 0.119523184636475 0.561926545342194 GO:0140791 histone H2AXS140 phosphatase activity 4/433 81/18639 0.0493827160493827 2.12573774698486 0.119523184636475 0.561926545342194 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 4/433 81/18639 0.0493827160493827 2.12573774698486 0.119523184636475 0.561926545342194 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 4/433 81/18639 0.0493827160493827 2.12573774698486 0.119523184636475 0.561926545342194 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 4/433 81/18639 0.0493827160493827 2.12573774698486 0.119523184636475 0.561926545342194 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 4/433 81/18639 0.0493827160493827 2.12573774698486 0.119523184636475 0.561926545342194 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 4/433 81/18639 0.0493827160493827 2.12573774698486 0.119523184636475 0.561926545342194 GO:1990439 MAP kinase serine/threonine phosphatase activity 4/433 81/18639 0.0493827160493827 2.12573774698486 0.119523184636475 0.561926545342194 GO:0001637 G protein-coupled chemoattractant receptor activity 2/433 26/18639 0.0769230769230769 3.31124533664949 0.121553736220556 0.561926545342194 GO:0004950 chemokine receptor activity 2/433 26/18639 0.0769230769230769 3.31124533664949 0.121553736220556 0.561926545342194 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 2/433 26/18639 0.0769230769230769 3.31124533664949 0.121553736220556 0.561926545342194 GO:0019865 immunoglobulin binding 2/433 26/18639 0.0769230769230769 3.31124533664949 0.121553736220556 0.561926545342194 GO:0030247 polysaccharide binding 2/433 26/18639 0.0769230769230769 3.31124533664949 0.121553736220556 0.561926545342194 GO:0050681 nuclear androgen receptor binding 2/433 26/18639 0.0769230769230769 3.31124533664949 0.121553736220556 0.561926545342194 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 4/433 82/18639 0.0487804878048781 2.09981411592407 0.123493315764491 0.561926545342194 GO:0033549 MAP kinase phosphatase activity 4/433 82/18639 0.0487804878048781 2.09981411592407 0.123493315764491 0.561926545342194 GO:0140272 exogenous protein binding 4/433 82/18639 0.0487804878048781 2.09981411592407 0.123493315764491 0.561926545342194 GO:0031267 small GTPase binding 10/433 283/18639 0.0353356890459364 1.5210667624185 0.12490976312875 0.561926545342194 GO:0016853 isomerase activity 7/433 180/18639 0.0388888888888889 1.67401847575058 0.126986959668288 0.561926545342194 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 4/433 83/18639 0.0481927710843374 2.07451515067197 0.127518944662435 0.561926545342194 GO:0004683 calcium/calmodulin-dependent protein kinase activity 2/433 27/18639 0.0740740740740741 3.18860662047729 0.129350614606807 0.561926545342194 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2/433 27/18639 0.0740740740740741 3.18860662047729 0.129350614606807 0.561926545342194 GO:0035401 histone H3Y41 kinase activity 5/433 115/18639 0.0434782608695652 1.87157345114971 0.129965553120305 0.561926545342194 GO:0101005 deubiquitinase activity 5/433 115/18639 0.0434782608695652 1.87157345114971 0.129965553120305 0.561926545342194 GO:0140801 histone H2AXY142 kinase activity 5/433 115/18639 0.0434782608695652 1.87157345114971 0.129965553120305 0.561926545342194 GO:0003925 G protein activity 3/433 54/18639 0.0555555555555556 2.39145496535797 0.130291258570276 0.561926545342194 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3/433 54/18639 0.0555555555555556 2.39145496535797 0.130291258570276 0.561926545342194 GO:0017018 myosin phosphatase activity 4/433 84/18639 0.0476190476190476 2.0498185417354 0.131598975196859 0.564413382510973 GO:0045499 chemorepellent activity 2/433 28/18639 0.0714285714285714 3.0747278126031 0.137259875464963 0.572781750588927 GO:0046875 ephrin receptor binding 2/433 28/18639 0.0714285714285714 3.0747278126031 0.137259875464963 0.572781750588927 GO:0046966 nuclear thyroid hormone receptor binding 2/433 28/18639 0.0714285714285714 3.0747278126031 0.137259875464963 0.572781750588927 GO:0051393 alpha-actinin binding 2/433 28/18639 0.0714285714285714 3.0747278126031 0.137259875464963 0.572781750588927 GO:0051537 2 iron, 2 sulfur cluster binding 2/433 28/18639 0.0714285714285714 3.0747278126031 0.137259875464963 0.572781750588927 GO:0016209 antioxidant activity 4/433 86/18639 0.0465116279069767 2.00214834309039 0.139917762040401 0.580733937070913 GO:0016504 peptidase activator activity 3/433 57/18639 0.0526315789473684 2.26558891454965 0.146358599800864 0.604218390621747 GO:0015215 nucleotide transmembrane transporter activity 2/433 30/18639 0.0666666666666667 2.86974595842956 0.153378333885197 0.626497744758582 GO:0033612 receptor serine/threonine kinase binding 2/433 30/18639 0.0666666666666667 2.86974595842956 0.153378333885197 0.626497744758582 GO:0004879 nuclear receptor activity 3/433 59/18639 0.0508474576271186 2.18878929032763 0.157410553031848 0.630807661153676 GO:0031593 polyubiquitin modification-dependent protein binding 3/433 59/18639 0.0508474576271186 2.18878929032763 0.157410553031848 0.630807661153676 GO:0036002 pre-mRNA binding 3/433 59/18639 0.0508474576271186 2.18878929032763 0.157410553031848 0.630807661153676 GO:0098531 ligand-modulated transcription factor activity 3/433 60/18639 0.05 2.15230946882217 0.163030671054034 0.630807661153676 GO:0000287 magnesium ion binding 8/433 230/18639 0.0347826086956522 1.49725876091977 0.168023820252726 0.630807661153676 GO:0030695 GTPase regulator activity 15/433 489/18639 0.0306748466257669 1.32043525694612 0.168076005864681 0.630807661153676 GO:0030515 snoRNA binding 2/433 32/18639 0.0625 2.69038683602771 0.16983835776018 0.630807661153676 GO:0043425 bHLH transcription factor binding 2/433 32/18639 0.0625 2.69038683602771 0.16983835776018 0.630807661153676 GO:0070717 poly-purine tract binding 2/433 32/18639 0.0625 2.69038683602771 0.16983835776018 0.630807661153676 GO:0120015 sterol transfer activity 2/433 32/18639 0.0625 2.69038683602771 0.16983835776018 0.630807661153676 GO:0060589 nucleoside-triphosphatase regulator activity 15/433 490/18639 0.0306122448979592 1.31774049111561 0.169943156371801 0.630807661153676 GO:0019783 ubiquitin-like protein peptidase activity 5/433 127/18639 0.0393700787401575 1.69473186521431 0.173792887483902 0.630807661153676 GO:0042826 histone deacetylase binding 5/433 127/18639 0.0393700787401575 1.69473186521431 0.173792887483902 0.630807661153676 GO:0019956 chemokine binding 2/433 33/18639 0.0606060606060606 2.60885996220869 0.178175888137803 0.630807661153676 GO:0030296 protein tyrosine kinase activator activity 2/433 33/18639 0.0606060606060606 2.60885996220869 0.178175888137803 0.630807661153676 GO:0071889 14-3-3 protein binding 2/433 33/18639 0.0606060606060606 2.60885996220869 0.178175888137803 0.630807661153676 GO:0140416 transcription regulator inhibitor activity 2/433 33/18639 0.0606060606060606 2.60885996220869 0.178175888137803 0.630807661153676 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 5/433 130/18639 0.0384615384615385 1.65562266832475 0.185545182052988 0.630807661153676 GO:0015035 protein-disulfide reductase activity 2/433 34/18639 0.0588235294117647 2.53212878684961 0.186574795550465 0.630807661153676 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/433 34/18639 0.0588235294117647 2.53212878684961 0.186574795550465 0.630807661153676 GO:0015631 tubulin binding 12/433 385/18639 0.0311688311688312 1.3416994091359 0.18715650286539 0.630807661153676 GO:0005154 epidermal growth factor receptor binding 2/433 35/18639 0.0571428571428571 2.45978225008248 0.195027751782175 0.630807661153676 GO:0043015 gamma-tubulin binding 2/433 35/18639 0.0571428571428571 2.45978225008248 0.195027751782175 0.630807661153676 GO:0051020 GTPase binding 10/433 315/18639 0.0317460317460317 1.36654569449027 0.199321167532638 0.630807661153676 GO:0141003 histone H2AX kinase activity 11/433 354/18639 0.0310734463276836 1.33759345520022 0.202904938779486 0.630807661153676 GO:0000993 RNA polymerase II complex binding 2/433 36/18639 0.0555555555555556 2.39145496535797 0.203527734511949 0.630807661153676 GO:0004190 aspartic-type endopeptidase activity 2/433 36/18639 0.0555555555555556 2.39145496535797 0.203527734511949 0.630807661153676 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/433 36/18639 0.0555555555555556 2.39145496535797 0.203527734511949 0.630807661153676 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/433 36/18639 0.0555555555555556 2.39145496535797 0.203527734511949 0.630807661153676 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/433 36/18639 0.0555555555555556 2.39145496535797 0.203527734511949 0.630807661153676 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 8/433 243/18639 0.0329218106995885 1.41715849798991 0.205545527119376 0.630807661153676 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/433 10/18639 0.1 4.30461893764434 0.209513686672325 0.630807661153676 GO:0004955 prostaglandin receptor activity 1/433 10/18639 0.1 4.30461893764434 0.209513686672325 0.630807661153676 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/433 10/18639 0.1 4.30461893764434 0.209513686672325 0.630807661153676 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/433 10/18639 0.1 4.30461893764434 0.209513686672325 0.630807661153676 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/433 10/18639 0.1 4.30461893764434 0.209513686672325 0.630807661153676 GO:0016427 tRNA (cytidine) methyltransferase activity 1/433 10/18639 0.1 4.30461893764434 0.209513686672325 0.630807661153676 GO:0030957 Tat protein binding 1/433 10/18639 0.1 4.30461893764434 0.209513686672325 0.630807661153676 GO:0031419 cobalamin binding 1/433 10/18639 0.1 4.30461893764434 0.209513686672325 0.630807661153676 GO:0033204 ribonuclease P RNA binding 1/433 10/18639 0.1 4.30461893764434 0.209513686672325 0.630807661153676 GO:0043422 protein kinase B binding 1/433 10/18639 0.1 4.30461893764434 0.209513686672325 0.630807661153676 GO:0050815 phosphoserine residue binding 1/433 10/18639 0.1 4.30461893764434 0.209513686672325 0.630807661153676 GO:0051864 histone H3K36 demethylase activity 1/433 10/18639 0.1 4.30461893764434 0.209513686672325 0.630807661153676 GO:0099122 RNA polymerase II C-terminal domain binding 1/433 10/18639 0.1 4.30461893764434 0.209513686672325 0.630807661153676 GO:0141109 transporter activator activity 1/433 10/18639 0.1 4.30461893764434 0.209513686672325 0.630807661153676 GO:0044325 transmembrane transporter binding 5/433 136/18639 0.0367647058823529 1.58258049178101 0.209870949275329 0.630807661153676 GO:0140996 histone H3 kinase activity 11/433 357/18639 0.030812324929972 1.32635317406408 0.210329354366626 0.630807661153676 GO:0004676 3-phosphoinositide-dependent protein kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:0004711 ribosomal protein S6 kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:0035175 histone H3S10 kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:0035979 histone H2AXS139 kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:0044022 histone H3S28 kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:0044023 histone H4S1 kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:0044024 histone H2AS1 kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:0044025 histone H2BS14 kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:0072354 histone H3T3 kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:0072371 histone H2AS121 kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:0072518 Rho-dependent protein serine/threonine kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:0140823 histone H2BS36 kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:0140855 histone H3S57 kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:0140995 histone H2A kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:0140997 histone H4 kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:0140998 histone H2B kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:1990244 histone H2AT120 kinase activity 8/433 245/18639 0.0326530612244898 1.40558985718999 0.211596474967569 0.630807661153676 GO:0004677 DNA-dependent protein kinase activity 8/433 246/18639 0.032520325203252 1.39987607728271 0.214647693872095 0.630807661153676 GO:0140857 histone H3T45 kinase activity 8/433 246/18639 0.032520325203252 1.39987607728271 0.214647693872095 0.630807661153676 GO:0035402 histone H3T11 kinase activity 8/433 247/18639 0.0323886639676113 1.39420856279979 0.21771571072361 0.630807661153676 GO:0035403 histone H3T6 kinase activity 8/433 247/18639 0.0323886639676113 1.39420856279979 0.21771571072361 0.630807661153676 GO:0035173 histone kinase activity 11/433 360/18639 0.0305555555555556 1.31530023094688 0.217867278908716 0.630807661153676 GO:0004722 protein serine/threonine phosphatase activity 4/433 103/18639 0.0388349514563107 1.67169667481334 0.21789191054468 0.630807661153676 GO:0106310 protein serine kinase activity 11/433 361/18639 0.0304709141274238 1.31165674000243 0.22040448035485 0.630807661153676 GO:0004679 AMP-activated protein kinase activity 8/433 248/18639 0.032258064516129 1.38858675407882 0.220800248275371 0.630807661153676 GO:0004252 serine-type endopeptidase activity 6/433 176/18639 0.0340909090909091 1.46748372874239 0.226428635096751 0.630807661153676 GO:0004713 protein tyrosine kinase activity 5/433 140/18639 0.0357142857142857 1.53736390630155 0.226631929283493 0.630807661153676 GO:0004954 prostanoid receptor activity 1/433 11/18639 0.0909090909090909 3.91328994331304 0.227887221143895 0.630807661153676 GO:0005536 D-glucose binding 1/433 11/18639 0.0909090909090909 3.91328994331304 0.227887221143895 0.630807661153676 GO:0008432 JUN kinase binding 1/433 11/18639 0.0909090909090909 3.91328994331304 0.227887221143895 0.630807661153676 GO:0010854 adenylate cyclase regulator activity 1/433 11/18639 0.0909090909090909 3.91328994331304 0.227887221143895 0.630807661153676 GO:0015173 aromatic amino acid transmembrane transporter activity 1/433 11/18639 0.0909090909090909 3.91328994331304 0.227887221143895 0.630807661153676 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/433 11/18639 0.0909090909090909 3.91328994331304 0.227887221143895 0.630807661153676 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/433 11/18639 0.0909090909090909 3.91328994331304 0.227887221143895 0.630807661153676 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/433 11/18639 0.0909090909090909 3.91328994331304 0.227887221143895 0.630807661153676 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/433 11/18639 0.0909090909090909 3.91328994331304 0.227887221143895 0.630807661153676 GO:0019107 myristoyltransferase activity 1/433 11/18639 0.0909090909090909 3.91328994331304 0.227887221143895 0.630807661153676 GO:0019215 intermediate filament binding 1/433 11/18639 0.0909090909090909 3.91328994331304 0.227887221143895 0.630807661153676 GO:0034713 type I transforming growth factor beta receptor binding 1/433 11/18639 0.0909090909090909 3.91328994331304 0.227887221143895 0.630807661153676 GO:0047676 arachidonate-CoA ligase activity 1/433 11/18639 0.0909090909090909 3.91328994331304 0.227887221143895 0.630807661153676 GO:0070697 activin receptor binding 1/433 11/18639 0.0909090909090909 3.91328994331304 0.227887221143895 0.630807661153676 GO:0140537 transcription regulator activator activity 1/433 11/18639 0.0909090909090909 3.91328994331304 0.227887221143895 0.630807661153676 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/433 39/18639 0.0512820512820513 2.20749689109966 0.229243994797149 0.630807661153676 GO:0005319 lipid transporter activity 6/433 178/18639 0.0337078651685393 1.45099514752056 0.233973181935736 0.630807661153676 GO:0042379 chemokine receptor binding 3/433 72/18639 0.0416666666666667 1.79359122401848 0.234356416359537 0.630807661153676 GO:0030331 nuclear estrogen receptor binding 2/433 40/18639 0.05 2.15230946882217 0.237867627517252 0.630807661153676 GO:0032451 demethylase activity 2/433 40/18639 0.05 2.15230946882217 0.237867627517252 0.630807661153676 GO:0019903 protein phosphatase binding 5/433 144/18639 0.0347222222222222 1.49465935334873 0.24377133270528 0.630807661153676 GO:0019955 cytokine binding 5/433 144/18639 0.0347222222222222 1.49465935334873 0.24377133270528 0.630807661153676 GO:0003720 telomerase activity 1/433 12/18639 0.0833333333333333 3.58718244803695 0.245834656898925 0.630807661153676 GO:0004126 cytidine deaminase activity 1/433 12/18639 0.0833333333333333 3.58718244803695 0.245834656898925 0.630807661153676 GO:0004300 enoyl-CoA hydratase activity 1/433 12/18639 0.0833333333333333 3.58718244803695 0.245834656898925 0.630807661153676 GO:0004526 ribonuclease P activity 1/433 12/18639 0.0833333333333333 3.58718244803695 0.245834656898925 0.630807661153676 GO:0005078 MAP-kinase scaffold activity 1/433 12/18639 0.0833333333333333 3.58718244803695 0.245834656898925 0.630807661153676 GO:0015269 calcium-activated potassium channel activity 1/433 12/18639 0.0833333333333333 3.58718244803695 0.245834656898925 0.630807661153676 GO:0031543 peptidyl-proline dioxygenase activity 1/433 12/18639 0.0833333333333333 3.58718244803695 0.245834656898925 0.630807661153676 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/433 12/18639 0.0833333333333333 3.58718244803695 0.245834656898925 0.630807661153676 GO:0035259 nuclear glucocorticoid receptor binding 1/433 12/18639 0.0833333333333333 3.58718244803695 0.245834656898925 0.630807661153676 GO:0042301 phosphate ion binding 1/433 12/18639 0.0833333333333333 3.58718244803695 0.245834656898925 0.630807661153676 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/433 12/18639 0.0833333333333333 3.58718244803695 0.245834656898925 0.630807661153676 GO:0070410 co-SMAD binding 1/433 12/18639 0.0833333333333333 3.58718244803695 0.245834656898925 0.630807661153676 GO:0097677 STAT family protein binding 1/433 12/18639 0.0833333333333333 3.58718244803695 0.245834656898925 0.630807661153676 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/433 12/18639 0.0833333333333333 3.58718244803695 0.245834656898925 0.630807661153676 GO:0008137 NADH dehydrogenase (ubiquinone) activity 2/433 41/18639 0.0487804878048781 2.09981411592407 0.24650741704323 0.630807661153676 GO:0017080 sodium channel regulator activity 2/433 41/18639 0.0487804878048781 2.09981411592407 0.24650741704323 0.630807661153676 GO:0048029 monosaccharide binding 3/433 74/18639 0.0405405405405405 1.74511578553149 0.246766727549754 0.630807661153676 GO:0001664 G protein-coupled receptor binding 9/433 297/18639 0.0303030303030303 1.30442998110435 0.255060203992326 0.639366159349044 GO:0016859 cis-trans isomerase activity 2/433 42/18639 0.0476190476190476 2.0498185417354 0.255157972625896 0.639366159349044 GO:0043175 RNA polymerase core enzyme binding 2/433 42/18639 0.0476190476190476 2.0498185417354 0.255157972625896 0.639366159349044 GO:0051536 iron-sulfur cluster binding 3/433 76/18639 0.0394736842105263 1.69919168591224 0.25927589022101 0.639366159349044 GO:0005200 structural constituent of cytoskeleton 4/433 112/18639 0.0357142857142857 1.53736390630155 0.263086389988834 0.639366159349044 GO:0003964 RNA-directed DNA polymerase activity 1/433 13/18639 0.0769230769230769 3.31124533664949 0.263365853203363 0.639366159349044 GO:0005542 folic acid binding 1/433 13/18639 0.0769230769230769 3.31124533664949 0.263365853203363 0.639366159349044 GO:0008035 high-density lipoprotein particle binding 1/433 13/18639 0.0769230769230769 3.31124533664949 0.263365853203363 0.639366159349044 GO:0008253 5'-nucleotidase activity 1/433 13/18639 0.0769230769230769 3.31124533664949 0.263365853203363 0.639366159349044 GO:0008417 fucosyltransferase activity 1/433 13/18639 0.0769230769230769 3.31124533664949 0.263365853203363 0.639366159349044 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/433 13/18639 0.0769230769230769 3.31124533664949 0.263365853203363 0.639366159349044 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/433 13/18639 0.0769230769230769 3.31124533664949 0.263365853203363 0.639366159349044 GO:0043560 insulin receptor substrate binding 1/433 13/18639 0.0769230769230769 3.31124533664949 0.263365853203363 0.639366159349044 GO:0070700 BMP receptor binding 1/433 13/18639 0.0769230769230769 3.31124533664949 0.263365853203363 0.639366159349044 GO:0089720 caspase binding 1/433 13/18639 0.0769230769230769 3.31124533664949 0.263365853203363 0.639366159349044 GO:0140333 glycerophospholipid flippase activity 1/433 13/18639 0.0769230769230769 3.31124533664949 0.263365853203363 0.639366159349044 GO:0003724 RNA helicase activity 3/433 77/18639 0.038961038961039 1.67712426141987 0.265561988122552 0.640668296345658 GO:0051540 metal cluster binding 3/433 77/18639 0.038961038961039 1.67712426141987 0.265561988122552 0.640668296345658 GO:0031406 carboxylic acid binding 6/433 187/18639 0.0320855614973262 1.38116115646343 0.268818345060774 0.64306081423399 GO:0003954 NADH dehydrogenase activity 2/433 44/18639 0.0454545454545455 1.95664497165652 0.272471013899549 0.64306081423399 GO:0043014 alpha-tubulin binding 2/433 44/18639 0.0454545454545455 1.95664497165652 0.272471013899549 0.64306081423399 GO:0140597 protein carrier chaperone 6/433 188/18639 0.0319148936170213 1.37381455456734 0.272769845074996 0.64306081423399 GO:0043177 organic acid binding 6/433 189/18639 0.0317460317460317 1.36654569449027 0.276735363912275 0.64306081423399 GO:0008186 ATP-dependent activity, acting on RNA 3/433 79/18639 0.0379746835443038 1.63466541935861 0.278186441650886 0.64306081423399 GO:0016835 carbon-oxygen lyase activity 3/433 79/18639 0.0379746835443038 1.63466541935861 0.278186441650886 0.64306081423399 GO:0005313 L-glutamate transmembrane transporter activity 1/433 14/18639 0.0714285714285714 3.0747278126031 0.280490441712057 0.64306081423399 GO:0008191 metalloendopeptidase inhibitor activity 1/433 14/18639 0.0714285714285714 3.0747278126031 0.280490441712057 0.64306081423399 GO:0008331 high voltage-gated calcium channel activity 1/433 14/18639 0.0714285714285714 3.0747278126031 0.280490441712057 0.64306081423399 GO:0015386 potassium:proton antiporter activity 1/433 14/18639 0.0714285714285714 3.0747278126031 0.280490441712057 0.64306081423399 GO:0032454 histone H3K9 demethylase activity 1/433 14/18639 0.0714285714285714 3.0747278126031 0.280490441712057 0.64306081423399 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/433 14/18639 0.0714285714285714 3.0747278126031 0.280490441712057 0.64306081423399 GO:0042043 neurexin family protein binding 1/433 14/18639 0.0714285714285714 3.0747278126031 0.280490441712057 0.64306081423399 GO:0043176 amine binding 1/433 14/18639 0.0714285714285714 3.0747278126031 0.280490441712057 0.64306081423399 GO:0044548 S100 protein binding 1/433 14/18639 0.0714285714285714 3.0747278126031 0.280490441712057 0.64306081423399 GO:0019902 phosphatase binding 6/433 190/18639 0.0315789473684211 1.35935334872979 0.280714370980381 0.64306081423399 GO:0009055 electron transfer activity 4/433 116/18639 0.0344827586206897 1.48435135780839 0.283721622807997 0.648026901798146 GO:1990782 protein tyrosine kinase binding 4/433 117/18639 0.0341880341880342 1.47166459406644 0.288919282645615 0.648169960681466 GO:0008236 serine-type peptidase activity 6/433 194/18639 0.0309278350515464 1.33132544463227 0.296754688133053 0.648169960681466 GO:0004467 long-chain fatty acid-CoA ligase activity 1/433 15/18639 0.0666666666666667 2.86974595842956 0.297217831711449 0.648169960681466 GO:0004559 alpha-mannosidase activity 1/433 15/18639 0.0666666666666667 2.86974595842956 0.297217831711449 0.648169960681466 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/433 15/18639 0.0666666666666667 2.86974595842956 0.297217831711449 0.648169960681466 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/433 15/18639 0.0666666666666667 2.86974595842956 0.297217831711449 0.648169960681466 GO:0004953 icosanoid receptor activity 1/433 15/18639 0.0666666666666667 2.86974595842956 0.297217831711449 0.648169960681466 GO:0005041 low-density lipoprotein particle receptor activity 1/433 15/18639 0.0666666666666667 2.86974595842956 0.297217831711449 0.648169960681466 GO:0008252 nucleotidase activity 1/433 15/18639 0.0666666666666667 2.86974595842956 0.297217831711449 0.648169960681466 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/433 15/18639 0.0666666666666667 2.86974595842956 0.297217831711449 0.648169960681466 GO:0033130 acetylcholine receptor binding 1/433 15/18639 0.0666666666666667 2.86974595842956 0.297217831711449 0.648169960681466 GO:0034483 heparan sulfate sulfotransferase activity 1/433 15/18639 0.0666666666666667 2.86974595842956 0.297217831711449 0.648169960681466 GO:0051371 muscle alpha-actinin binding 1/433 15/18639 0.0666666666666667 2.86974595842956 0.297217831711449 0.648169960681466 GO:0061578 K63-linked deubiquitinase activity 1/433 15/18639 0.0666666666666667 2.86974595842956 0.297217831711449 0.648169960681466 GO:0140161 monocarboxylate:sodium symporter activity 1/433 15/18639 0.0666666666666667 2.86974595842956 0.297217831711449 0.648169960681466 GO:0140776 protein-containing complex destabilizing activity 1/433 15/18639 0.0666666666666667 2.86974595842956 0.297217831711449 0.648169960681466 GO:0005504 fatty acid binding 2/433 47/18639 0.0425531914893617 1.83175273942312 0.298399955692067 0.648914833223311 GO:0005125 cytokine activity 7/433 234/18639 0.0299145299145299 1.28770651980814 0.302304671311489 0.65071551120069 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/433 48/18639 0.0416666666666667 1.79359122401848 0.307014815258225 0.65071551120069 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/433 48/18639 0.0416666666666667 1.79359122401848 0.307014815258225 0.65071551120069 GO:0051117 ATPase binding 3/433 84/18639 0.0357142857142857 1.53736390630155 0.309956403024165 0.65071551120069 GO:0017171 serine hydrolase activity 6/433 198/18639 0.0303030303030303 1.30442998110435 0.312968556187561 0.65071551120069 GO:0003688 DNA replication origin binding 1/433 16/18639 0.0625 2.69038683602771 0.313557215241783 0.65071551120069 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/433 16/18639 0.0625 2.69038683602771 0.313557215241783 0.65071551120069 GO:0004708 MAP kinase kinase activity 1/433 16/18639 0.0625 2.69038683602771 0.313557215241783 0.65071551120069 GO:0005149 interleukin-1 receptor binding 1/433 16/18639 0.0625 2.69038683602771 0.313557215241783 0.65071551120069 GO:0005521 lamin binding 1/433 16/18639 0.0625 2.69038683602771 0.313557215241783 0.65071551120069 GO:0008296 3'-5'-DNA exonuclease activity 1/433 16/18639 0.0625 2.69038683602771 0.313557215241783 0.65071551120069 GO:0015385 sodium:proton antiporter activity 1/433 16/18639 0.0625 2.69038683602771 0.313557215241783 0.65071551120069 GO:0015923 mannosidase activity 1/433 16/18639 0.0625 2.69038683602771 0.313557215241783 0.65071551120069 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/433 16/18639 0.0625 2.69038683602771 0.313557215241783 0.65071551120069 GO:0034450 ubiquitin-ubiquitin ligase activity 1/433 16/18639 0.0625 2.69038683602771 0.313557215241783 0.65071551120069 GO:0070411 I-SMAD binding 1/433 16/18639 0.0625 2.69038683602771 0.313557215241783 0.65071551120069 GO:0140327 flippase activity 1/433 16/18639 0.0625 2.69038683602771 0.313557215241783 0.65071551120069 GO:0015079 potassium ion transmembrane transporter activity 5/433 160/18639 0.03125 1.34519341801386 0.315136638927703 0.651470983545023 GO:0016763 pentosyltransferase activity 2/433 49/18639 0.0408163265306122 1.75698732148749 0.315608999800309 0.651470983545023 GO:0015605 organophosphate ester transmembrane transporter activity 2/433 50/18639 0.04 1.72184757505774 0.324178826833084 0.659035144203194 GO:0004549 tRNA-specific ribonuclease activity 1/433 17/18639 0.0588235294117647 2.53212878684961 0.329517572101597 0.659035144203194 GO:0004550 nucleoside diphosphate kinase activity 1/433 17/18639 0.0588235294117647 2.53212878684961 0.329517572101597 0.659035144203194 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/433 17/18639 0.0588235294117647 2.53212878684961 0.329517572101597 0.659035144203194 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/433 17/18639 0.0588235294117647 2.53212878684961 0.329517572101597 0.659035144203194 GO:0016018 cyclosporin A binding 1/433 17/18639 0.0588235294117647 2.53212878684961 0.329517572101597 0.659035144203194 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/433 17/18639 0.0588235294117647 2.53212878684961 0.329517572101597 0.659035144203194 GO:0030548 acetylcholine receptor regulator activity 1/433 17/18639 0.0588235294117647 2.53212878684961 0.329517572101597 0.659035144203194 GO:0031489 myosin V binding 1/433 17/18639 0.0588235294117647 2.53212878684961 0.329517572101597 0.659035144203194 GO:0038191 neuropilin binding 1/433 17/18639 0.0588235294117647 2.53212878684961 0.329517572101597 0.659035144203194 GO:0046965 nuclear retinoid X receptor binding 1/433 17/18639 0.0588235294117647 2.53212878684961 0.329517572101597 0.659035144203194 GO:0070492 oligosaccharide binding 1/433 17/18639 0.0588235294117647 2.53212878684961 0.329517572101597 0.659035144203194 GO:0005272 sodium channel activity 2/433 51/18639 0.0392156862745098 1.68808585789974 0.332720795325594 0.663722103336844 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 13/433 484/18639 0.0268595041322314 1.1561993014334 0.336074260899423 0.667727130067946 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 3/433 89/18639 0.0337078651685393 1.45099514752056 0.341832028026358 0.667727130067946 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 3/433 89/18639 0.0337078651685393 1.45099514752056 0.341832028026358 0.667727130067946 GO:0008525 phosphatidylcholine transporter activity 1/433 18/18639 0.0555555555555556 2.39145496535797 0.34510767473719 0.667727130067946 GO:0015172 acidic amino acid transmembrane transporter activity 1/433 18/18639 0.0555555555555556 2.39145496535797 0.34510767473719 0.667727130067946 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/433 18/18639 0.0555555555555556 2.39145496535797 0.34510767473719 0.667727130067946 GO:0017075 syntaxin-1 binding 1/433 18/18639 0.0555555555555556 2.39145496535797 0.34510767473719 0.667727130067946 GO:0030228 lipoprotein particle receptor activity 1/433 18/18639 0.0555555555555556 2.39145496535797 0.34510767473719 0.667727130067946 GO:0031690 adrenergic receptor binding 1/433 18/18639 0.0555555555555556 2.39145496535797 0.34510767473719 0.667727130067946 GO:0050811 GABA receptor binding 1/433 18/18639 0.0555555555555556 2.39145496535797 0.34510767473719 0.667727130067946 GO:0098641 cadherin binding involved in cell-cell adhesion 1/433 18/18639 0.0555555555555556 2.39145496535797 0.34510767473719 0.667727130067946 GO:0099602 neurotransmitter receptor regulator activity 1/433 18/18639 0.0555555555555556 2.39145496535797 0.34510767473719 0.667727130067946 GO:0019210 kinase inhibitor activity 3/433 90/18639 0.0333333333333333 1.43487297921478 0.348200099243982 0.670350315751506 GO:0140793 histone H2AXY142 phosphatase activity 3/433 90/18639 0.0333333333333333 1.43487297921478 0.348200099243982 0.670350315751506 GO:0005544 calcium-dependent phospholipid binding 2/433 53/18639 0.0377358490566038 1.62438450477145 0.349708021577726 0.671578588701504 GO:0015291 secondary active transmembrane transporter activity 8/433 287/18639 0.0278745644599303 1.19989378052804 0.350834298534339 0.672069673619132 GO:0001216 DNA-binding transcription activator activity 13/433 491/18639 0.0264765784114053 1.13971580833761 0.354733324215766 0.677856748253889 GO:0015485 cholesterol binding 2/433 54/18639 0.037037037037037 1.59430331023865 0.358147127847243 0.678486497100526 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/433 19/18639 0.0526315789473684 2.26558891454965 0.360336093019709 0.678486497100526 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/433 19/18639 0.0526315789473684 2.26558891454965 0.360336093019709 0.678486497100526 GO:0022821 solute:potassium antiporter activity 1/433 19/18639 0.0526315789473684 2.26558891454965 0.360336093019709 0.678486497100526 GO:0050145 nucleoside monophosphate kinase activity 1/433 19/18639 0.0526315789473684 2.26558891454965 0.360336093019709 0.678486497100526 GO:0140036 ubiquitin-modified protein reader activity 1/433 19/18639 0.0526315789473684 2.26558891454965 0.360336093019709 0.678486497100526 GO:0170055 lipid transmembrane transporter activity 2/433 56/18639 0.0357142857142857 1.53736390630155 0.374902134263748 0.683853173910395 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/433 20/18639 0.05 2.15230946882217 0.375211198912431 0.683853173910395 GO:0010851 cyclase regulator activity 1/433 20/18639 0.05 2.15230946882217 0.375211198912431 0.683853173910395 GO:0016004 phospholipase activator activity 1/433 20/18639 0.05 2.15230946882217 0.375211198912431 0.683853173910395 GO:0016505 peptidase activator activity involved in apoptotic process 1/433 20/18639 0.05 2.15230946882217 0.375211198912431 0.683853173910395 GO:0030742 GTP-dependent protein binding 1/433 20/18639 0.05 2.15230946882217 0.375211198912431 0.683853173910395 GO:0031418 L-ascorbic acid binding 1/433 20/18639 0.05 2.15230946882217 0.375211198912431 0.683853173910395 GO:0016887 ATP hydrolysis activity 11/433 417/18639 0.026378896882494 1.13551099074551 0.376946463637898 0.683853173910395 GO:0004601 peroxidase activity 2/433 57/18639 0.0350877192982456 1.51039260969977 0.383212808244216 0.683853173910395 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/433 57/18639 0.0350877192982456 1.51039260969977 0.383212808244216 0.683853173910395 GO:0015297 antiporter activity 4/433 135/18639 0.0296296296296296 1.27544264819092 0.383686068379103 0.683853173910395 GO:0003735 structural constituent of ribosome 5/433 175/18639 0.0285714285714286 1.22989112504124 0.384118034056301 0.683853173910395 GO:0003713 transcription coactivator activity 7/433 256/18639 0.02734375 1.17704424076212 0.385004742409507 0.683853173910395 GO:0140789 histone phosphatase activity 4/433 136/18639 0.0294117647058824 1.26606439342481 0.38895319320043 0.683853173910395 GO:0005248 voltage-gated sodium channel activity 1/433 21/18639 0.0476190476190476 2.0498185417354 0.389741171030746 0.683853173910395 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/433 21/18639 0.0476190476190476 2.0498185417354 0.389741171030746 0.683853173910395 GO:0010314 phosphatidylinositol-5-phosphate binding 1/433 21/18639 0.0476190476190476 2.0498185417354 0.389741171030746 0.683853173910395 GO:0015125 bile acid transmembrane transporter activity 1/433 21/18639 0.0476190476190476 2.0498185417354 0.389741171030746 0.683853173910395 GO:0035613 RNA stem-loop binding 1/433 21/18639 0.0476190476190476 2.0498185417354 0.389741171030746 0.683853173910395 GO:0072542 protein phosphatase activator activity 1/433 21/18639 0.0476190476190476 2.0498185417354 0.389741171030746 0.683853173910395 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/433 58/18639 0.0344827586206897 1.48435135780839 0.391475683102865 0.683853173910395 GO:0004725 protein tyrosine phosphatase activity 3/433 98/18639 0.0306122448979592 1.31774049111561 0.398791310707581 0.683853173910395 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/433 59/18639 0.0338983050847458 1.45919286021842 0.399688494684304 0.683853173910395 GO:0045309 protein phosphorylated amino acid binding 2/433 59/18639 0.0338983050847458 1.45919286021842 0.399688494684304 0.683853173910395 GO:0070063 RNA polymerase binding 2/433 59/18639 0.0338983050847458 1.45919286021842 0.399688494684304 0.683853173910395 GO:0008093 cytoskeletal anchor activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0015377 chloride:monoatomic cation symporter activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0031683 G-protein beta/gamma-subunit complex binding 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0032931 histone H3K56 acetyltransferase activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0034062 5'-3' RNA polymerase activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0043992 histone H3K9 acetyltransferase activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0043993 histone H3K18 acetyltransferase activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0043994 histone H3K23 acetyltransferase activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0043999 histone H2AK5 acetyltransferase activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0044012 histone H2AK9 acetyltransferase activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0044014 histone H2BK5 acetyltransferase activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0044015 histone H2BK12 acetyltransferase activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0044016 histone H3K4 acetyltransferase activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0044017 histone H3K27 acetyltransferase activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0044018 histone H3K36 acetyltransferase activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0046972 histone H4K16 acetyltransferase activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0061133 endopeptidase activator activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0097747 RNA polymerase activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0140035 ubiquitin-like protein reader activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0140908 histone H3K122 acetyltransferase activity 1/433 22/18639 0.0454545454545455 1.95664497165652 0.403933999097332 0.683853173910395 GO:0001098 basal transcription machinery binding 2/433 60/18639 0.0333333333333333 1.43487297921478 0.407849109292244 0.685968436543818 GO:0001099 basal RNA polymerase II transcription machinery binding 2/433 60/18639 0.0333333333333333 1.43487297921478 0.407849109292244 0.685968436543818 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/433 60/18639 0.0333333333333333 1.43487297921478 0.407849109292244 0.685968436543818 GO:0016836 hydro-lyase activity 2/433 61/18639 0.0327868852459016 1.4113504713588 0.415955518874681 0.689187309751392 GO:0000295 adenine nucleotide transmembrane transporter activity 1/433 23/18639 0.0434782608695652 1.87157345114971 0.417797488294885 0.689187309751392 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/433 23/18639 0.0434782608695652 1.87157345114971 0.417797488294885 0.689187309751392 GO:0008171 O-methyltransferase activity 1/433 23/18639 0.0434782608695652 1.87157345114971 0.417797488294885 0.689187309751392 GO:0043274 phospholipase binding 1/433 23/18639 0.0434782608695652 1.87157345114971 0.417797488294885 0.689187309751392 GO:0044013 histone H2B acetyltransferase activity 1/433 23/18639 0.0434782608695652 1.87157345114971 0.417797488294885 0.689187309751392 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/433 23/18639 0.0434782608695652 1.87157345114971 0.417797488294885 0.689187309751392 GO:0140103 catalytic activity, acting on a glycoprotein 1/433 23/18639 0.0434782608695652 1.87157345114971 0.417797488294885 0.689187309751392 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/433 23/18639 0.0434782608695652 1.87157345114971 0.417797488294885 0.689187309751392 GO:0015179 L-amino acid transmembrane transporter activity 2/433 62/18639 0.032258064516129 1.38858675407882 0.424005836361532 0.689805062029112 GO:0004674 protein serine/threonine kinase activity 11/433 433/18639 0.0254041570438799 1.09355215505976 0.424466017435816 0.689805062029112 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/433 24/18639 0.0416666666666667 1.79359122401848 0.431339263518795 0.689805062029112 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/433 24/18639 0.0416666666666667 1.79359122401848 0.431339263518795 0.689805062029112 GO:0005540 hyaluronic acid binding 1/433 24/18639 0.0416666666666667 1.79359122401848 0.431339263518795 0.689805062029112 GO:0015295 solute:proton symporter activity 1/433 24/18639 0.0416666666666667 1.79359122401848 0.431339263518795 0.689805062029112 GO:0030552 cAMP binding 1/433 24/18639 0.0416666666666667 1.79359122401848 0.431339263518795 0.689805062029112 GO:0035035 histone acetyltransferase binding 1/433 24/18639 0.0416666666666667 1.79359122401848 0.431339263518795 0.689805062029112 GO:0043998 histone H2A acetyltransferase activity 1/433 24/18639 0.0416666666666667 1.79359122401848 0.431339263518795 0.689805062029112 GO:0048027 mRNA 5'-UTR binding 1/433 24/18639 0.0416666666666667 1.79359122401848 0.431339263518795 0.689805062029112 GO:0050431 transforming growth factor beta binding 1/433 24/18639 0.0416666666666667 1.79359122401848 0.431339263518795 0.689805062029112 GO:0050699 WW domain binding 1/433 24/18639 0.0416666666666667 1.79359122401848 0.431339263518795 0.689805062029112 GO:0060229 lipase activator activity 1/433 24/18639 0.0416666666666667 1.79359122401848 0.431339263518795 0.689805062029112 GO:0070840 dynein complex binding 1/433 24/18639 0.0416666666666667 1.79359122401848 0.431339263518795 0.689805062029112 GO:1901682 sulfur compound transmembrane transporter activity 2/433 63/18639 0.0317460317460317 1.36654569449027 0.431998291150254 0.689805062029112 GO:0015293 symporter activity 4/433 146/18639 0.0273972602739726 1.17934765414913 0.441153351390814 0.689805062029112 GO:0003707 nuclear steroid receptor activity 1/433 25/18639 0.04 1.72184757505774 0.44456677353203 0.689805062029112 GO:0008139 nuclear localization sequence binding 1/433 25/18639 0.04 1.72184757505774 0.44456677353203 0.689805062029112 GO:0008483 transaminase activity 1/433 25/18639 0.04 1.72184757505774 0.44456677353203 0.689805062029112 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/433 25/18639 0.04 1.72184757505774 0.44456677353203 0.689805062029112 GO:0015645 fatty acid ligase activity 1/433 25/18639 0.04 1.72184757505774 0.44456677353203 0.689805062029112 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/433 25/18639 0.04 1.72184757505774 0.44456677353203 0.689805062029112 GO:0017056 structural constituent of nuclear pore 1/433 25/18639 0.04 1.72184757505774 0.44456677353203 0.689805062029112 GO:0019211 phosphatase activator activity 1/433 25/18639 0.04 1.72184757505774 0.44456677353203 0.689805062029112 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/433 25/18639 0.04 1.72184757505774 0.44456677353203 0.689805062029112 GO:0019707 protein-cysteine S-acyltransferase activity 1/433 25/18639 0.04 1.72184757505774 0.44456677353203 0.689805062029112 GO:0042974 nuclear retinoic acid receptor binding 1/433 25/18639 0.04 1.72184757505774 0.44456677353203 0.689805062029112 GO:0047617 fatty acyl-CoA hydrolase activity 1/433 25/18639 0.04 1.72184757505774 0.44456677353203 0.689805062029112 GO:0120515 fatty acid-CoA ligase activity 1/433 25/18639 0.04 1.72184757505774 0.44456677353203 0.689805062029112 GO:0005085 guanyl-nucleotide exchange factor activity 6/433 230/18639 0.0260869565217391 1.12294407068983 0.445058041026807 0.689805062029112 GO:0038024 cargo receptor activity 2/433 65/18639 0.0307692307692308 1.3244981346598 0.447803086475989 0.689805062029112 GO:0120013 lipid transfer activity 2/433 65/18639 0.0307692307692308 1.3244981346598 0.447803086475989 0.689805062029112 GO:0160215 deacylase activity 2/433 65/18639 0.0307692307692308 1.3244981346598 0.447803086475989 0.689805062029112 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/433 26/18639 0.0384615384615385 1.65562266832475 0.457487295024489 0.689805062029112 GO:0004529 DNA exonuclease activity 1/433 26/18639 0.0384615384615385 1.65562266832475 0.457487295024489 0.689805062029112 GO:0005160 transforming growth factor beta receptor binding 1/433 26/18639 0.0384615384615385 1.65562266832475 0.457487295024489 0.689805062029112 GO:0005227 calcium-activated cation channel activity 1/433 26/18639 0.0384615384615385 1.65562266832475 0.457487295024489 0.689805062029112 GO:0008143 poly(A) binding 1/433 26/18639 0.0384615384615385 1.65562266832475 0.457487295024489 0.689805062029112 GO:0015216 purine nucleotide transmembrane transporter activity 1/433 26/18639 0.0384615384615385 1.65562266832475 0.457487295024489 0.689805062029112 GO:0016289 acyl-CoA hydrolase activity 1/433 26/18639 0.0384615384615385 1.65562266832475 0.457487295024489 0.689805062029112 GO:0043548 phosphatidylinositol 3-kinase binding 1/433 26/18639 0.0384615384615385 1.65562266832475 0.457487295024489 0.689805062029112 GO:0050750 low-density lipoprotein particle receptor binding 1/433 26/18639 0.0384615384615385 1.65562266832475 0.457487295024489 0.689805062029112 GO:0051139 metal cation:proton antiporter activity 1/433 26/18639 0.0384615384615385 1.65562266832475 0.457487295024489 0.689805062029112 GO:0097602 cullin family protein binding 1/433 26/18639 0.0384615384615385 1.65562266832475 0.457487295024489 0.689805062029112 GO:0008173 RNA methyltransferase activity 2/433 67/18639 0.0298507462686567 1.28496087690876 0.463357906748444 0.697294939590252 GO:0005044 scavenger receptor activity 1/433 27/18639 0.037037037037037 1.59430331023865 0.470107936579015 0.697968411159879 GO:0008266 poly(U) RNA binding 1/433 27/18639 0.037037037037037 1.59430331023865 0.470107936579015 0.697968411159879 GO:0016405 CoA-ligase activity 1/433 27/18639 0.037037037037037 1.59430331023865 0.470107936579015 0.697968411159879 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/433 27/18639 0.037037037037037 1.59430331023865 0.470107936579015 0.697968411159879 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/433 27/18639 0.037037037037037 1.59430331023865 0.470107936579015 0.697968411159879 GO:0035255 ionotropic glutamate receptor binding 1/433 27/18639 0.037037037037037 1.59430331023865 0.470107936579015 0.697968411159879 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 2/433 68/18639 0.0294117647058824 1.26606439342481 0.471038267116965 0.697968411159879 GO:0032934 sterol binding 2/433 68/18639 0.0294117647058824 1.26606439342481 0.471038267116965 0.697968411159879 GO:1902936 phosphatidylinositol bisphosphate binding 3/433 111/18639 0.027027027027027 1.16341052368766 0.478329673473956 0.702717577444657 GO:0002039 p53 binding 2/433 69/18639 0.0289855072463768 1.24771563409981 0.478652351764893 0.702717577444657 GO:0008080 N-acetyltransferase activity 2/433 69/18639 0.0289855072463768 1.24771563409981 0.478652351764893 0.702717577444657 GO:0008527 taste receptor activity 1/433 28/18639 0.0357142857142857 1.53736390630155 0.482435642546202 0.702717577444657 GO:0036408 histone H3K14 acetyltransferase activity 1/433 28/18639 0.0357142857142857 1.53736390630155 0.482435642546202 0.702717577444657 GO:0050698 proteoglycan sulfotransferase activity 1/433 28/18639 0.0357142857142857 1.53736390630155 0.482435642546202 0.702717577444657 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/433 28/18639 0.0357142857142857 1.53736390630155 0.482435642546202 0.702717577444657 GO:0097718 disordered domain specific binding 1/433 28/18639 0.0357142857142857 1.53736390630155 0.482435642546202 0.702717577444657 GO:0141052 histone H3 demethylase activity 1/433 28/18639 0.0357142857142857 1.53736390630155 0.482435642546202 0.702717577444657 GO:0043022 ribosome binding 3/433 112/18639 0.0267857142857143 1.15302292972616 0.484253800542354 0.704037540524854 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/433 70/18639 0.0285714285714286 1.22989112504124 0.486199090510644 0.705537026079355 GO:0003785 actin monomer binding 1/433 29/18639 0.0344827586206897 1.48435135780839 0.494477196830093 0.710868521327434 GO:0005416 amino acid:monoatomic cation symporter activity 1/433 29/18639 0.0344827586206897 1.48435135780839 0.494477196830093 0.710868521327434 GO:0010484 histone H3 acetyltransferase activity 1/433 29/18639 0.0344827586206897 1.48435135780839 0.494477196830093 0.710868521327434 GO:0016417 S-acyltransferase activity 1/433 29/18639 0.0344827586206897 1.48435135780839 0.494477196830093 0.710868521327434 GO:0043236 laminin binding 1/433 29/18639 0.0344827586206897 1.48435135780839 0.494477196830093 0.710868521327434 GO:0022804 active transmembrane transporter activity 11/433 457/18639 0.0240700218818381 1.03612272022074 0.495424401066551 0.710906389634531 GO:0008187 poly-pyrimidine tract binding 1/433 30/18639 0.0333333333333333 1.43487297921478 0.506239226586814 0.715781470558645 GO:0016769 transferase activity, transferring nitrogenous groups 1/433 30/18639 0.0333333333333333 1.43487297921478 0.506239226586814 0.715781470558645 GO:0022839 monoatomic ion-gated channel activity 1/433 30/18639 0.0333333333333333 1.43487297921478 0.506239226586814 0.715781470558645 GO:0032452 histone demethylase activity 1/433 30/18639 0.0333333333333333 1.43487297921478 0.506239226586814 0.715781470558645 GO:0043995 histone H4K5 acetyltransferase activity 1/433 30/18639 0.0333333333333333 1.43487297921478 0.506239226586814 0.715781470558645 GO:0043996 histone H4K8 acetyltransferase activity 1/433 30/18639 0.0333333333333333 1.43487297921478 0.506239226586814 0.715781470558645 GO:0043997 histone H4K12 acetyltransferase activity 1/433 30/18639 0.0333333333333333 1.43487297921478 0.506239226586814 0.715781470558645 GO:0048019 receptor antagonist activity 1/433 30/18639 0.0333333333333333 1.43487297921478 0.506239226586814 0.715781470558645 GO:0015294 solute:monoatomic cation symporter activity 3/433 116/18639 0.0258620689655172 1.1132635183563 0.507619885999166 0.716249466661401 GO:0004521 RNA endonuclease activity 2/433 73/18639 0.0273972602739726 1.17934765414913 0.508425787215606 0.716249466661401 GO:0099106 ion channel regulator activity 4/433 160/18639 0.025 1.07615473441109 0.511759703522887 0.717569434303489 GO:0005164 tumor necrosis factor receptor binding 1/433 31/18639 0.032258064516129 1.38858675407882 0.517728205838139 0.717569434303489 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/433 31/18639 0.032258064516129 1.38858675407882 0.517728205838139 0.717569434303489 GO:0016411 acylglycerol O-acyltransferase activity 1/433 31/18639 0.032258064516129 1.38858675407882 0.517728205838139 0.717569434303489 GO:0016878 acid-thiol ligase activity 1/433 31/18639 0.032258064516129 1.38858675407882 0.517728205838139 0.717569434303489 GO:0070273 phosphatidylinositol-4-phosphate binding 1/433 31/18639 0.032258064516129 1.38858675407882 0.517728205838139 0.717569434303489 GO:0070325 lipoprotein particle receptor binding 1/433 31/18639 0.032258064516129 1.38858675407882 0.517728205838139 0.717569434303489 GO:0072349 modified amino acid transmembrane transporter activity 1/433 31/18639 0.032258064516129 1.38858675407882 0.517728205838139 0.717569434303489 GO:0140457 protein demethylase activity 1/433 31/18639 0.032258064516129 1.38858675407882 0.517728205838139 0.717569434303489 GO:0140104 molecular carrier activity 6/433 249/18639 0.0240963855421687 1.03725757533599 0.521504452922516 0.721507952788858 GO:0042910 xenobiotic transmembrane transporter activity 1/433 32/18639 0.03125 1.34519341801386 0.528950459001944 0.727094728005048 GO:0071813 lipoprotein particle binding 1/433 32/18639 0.03125 1.34519341801386 0.528950459001944 0.727094728005048 GO:0071814 protein-lipid complex binding 1/433 32/18639 0.03125 1.34519341801386 0.528950459001944 0.727094728005048 GO:0017022 myosin binding 2/433 76/18639 0.0263157894736842 1.13279445727483 0.530015647405069 0.727094728005048 GO:0015081 sodium ion transmembrane transporter activity 4/433 164/18639 0.024390243902439 1.04990705796203 0.531193557765346 0.727094728005048 GO:0140713 histone chaperone activity 4/433 164/18639 0.024390243902439 1.04990705796203 0.531193557765346 0.727094728005048 GO:0003697 single-stranded DNA binding 3/433 121/18639 0.0247933884297521 1.06726089363083 0.536031765222165 0.731124598500904 GO:0015108 chloride transmembrane transporter activity 3/433 121/18639 0.0247933884297521 1.06726089363083 0.536031765222165 0.731124598500904 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/433 122/18639 0.0245901639344262 1.0585128535191 0.54160189217497 0.737419154777914 GO:0016247 channel regulator activity 4/433 168/18639 0.0238095238095238 1.0249092708677 0.550240319333112 0.739713207672447 GO:0008175 tRNA methyltransferase activity 1/433 34/18639 0.0294117647058824 1.26606439342481 0.550619357335115 0.739713207672447 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/433 34/18639 0.0294117647058824 1.26606439342481 0.550619357335115 0.739713207672447 GO:0016831 carboxy-lyase activity 1/433 34/18639 0.0294117647058824 1.26606439342481 0.550619357335115 0.739713207672447 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/433 34/18639 0.0294117647058824 1.26606439342481 0.550619357335115 0.739713207672447 GO:0019825 oxygen binding 1/433 34/18639 0.0294117647058824 1.26606439342481 0.550619357335115 0.739713207672447 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/433 34/18639 0.0294117647058824 1.26606439342481 0.550619357335115 0.739713207672447 GO:0033293 monocarboxylic acid binding 2/433 79/18639 0.0253164556962025 1.08977694623907 0.550952194833752 0.739713207672447 GO:0005267 potassium channel activity 3/433 124/18639 0.0241935483870968 1.04144006555911 0.552625655302208 0.740671885231431 GO:0000049 tRNA binding 2/433 80/18639 0.025 1.07615473441109 0.557783774104658 0.742971123540458 GO:0048306 calcium-dependent protein binding 2/433 80/18639 0.025 1.07615473441109 0.557783774104658 0.742971123540458 GO:0141108 transporter regulator activity 4/433 170/18639 0.0235294117647059 1.01285151473985 0.559610346592406 0.742971123540458 GO:0005343 organic acid:sodium symporter activity 1/433 35/18639 0.0285714285714286 1.22989112504124 0.561077933969025 0.742971123540458 GO:0010485 histone H4 acetyltransferase activity 1/433 35/18639 0.0285714285714286 1.22989112504124 0.561077933969025 0.742971123540458 GO:0034061 DNA polymerase activity 1/433 35/18639 0.0285714285714286 1.22989112504124 0.561077933969025 0.742971123540458 GO:0140566 histone reader activity 1/433 35/18639 0.0285714285714286 1.22989112504124 0.561077933969025 0.742971123540458 GO:0015101 organic cation transmembrane transporter activity 2/433 81/18639 0.0246913580246914 1.06286887349243 0.564541169453353 0.745001338150407 GO:0030971 receptor tyrosine kinase binding 2/433 81/18639 0.0246913580246914 1.06286887349243 0.564541169453353 0.745001338150407 GO:0005484 SNAP receptor activity 1/433 36/18639 0.0277777777777778 1.19572748267898 0.571293653953512 0.7500658177757 GO:0016409 palmitoyltransferase activity 1/433 36/18639 0.0277777777777778 1.19572748267898 0.571293653953512 0.7500658177757 GO:0045505 dynein intermediate chain binding 1/433 36/18639 0.0277777777777778 1.19572748267898 0.571293653953512 0.7500658177757 GO:0140030 modification-dependent protein binding 4/433 173/18639 0.023121387283237 0.99528761564031 0.573465500494907 0.751319038086367 GO:0031490 chromatin DNA binding 3/433 128/18639 0.0234375 1.00889506351039 0.574194601646317 0.751319038086367 GO:0005254 chloride channel activity 2/433 83/18639 0.0240963855421687 1.03725757533599 0.577832470257338 0.753524775403151 GO:0030165 PDZ domain binding 2/433 83/18639 0.0240963855421687 1.03725757533599 0.577832470257338 0.753524775403151 GO:0019213 deacetylase activity 1/433 37/18639 0.027027027027027 1.16341052368766 0.581272143865792 0.755458072498975 GO:0030551 cyclic nucleotide binding 1/433 37/18639 0.027027027027027 1.16341052368766 0.581272143865792 0.755458072498975 GO:0004721 phosphoprotein phosphatase activity 4/433 175/18639 0.0228571428571429 0.983912900032992 0.582565195439985 0.755866102318771 GO:0004860 protein kinase inhibitor activity 2/433 84/18639 0.0238095238095238 1.0249092708677 0.584366032872781 0.756930498956019 GO:0005262 calcium channel activity 3/433 131/18639 0.0229007633587786 0.985790596407101 0.589940320679267 0.761130821397572 GO:0005109 frizzled binding 1/433 38/18639 0.0263157894736842 1.13279445727483 0.591018900220275 0.761130821397572 GO:0043531 ADP binding 1/433 38/18639 0.0263157894736842 1.13279445727483 0.591018900220275 0.761130821397572 GO:0043021 ribonucleoprotein complex binding 4/433 177/18639 0.0225988700564972 0.972795240145614 0.591552451863398 0.761130821397572 GO:0005179 hormone activity 3/433 132/18639 0.0227272727272727 0.97832248582826 0.595105045001197 0.764427778271088 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/433 86/18639 0.0232558139534884 1.0010741715452 0.597208481074965 0.765855394335338 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/433 39/18639 0.0256410256410256 1.10374844554983 0.600539292468253 0.768179524228803 GO:0046873 metal ion transmembrane transporter activity 10/433 450/18639 0.0222222222222222 0.956581986143187 0.601549111103696 0.768179524228803 GO:0008081 phosphoric diester hydrolase activity 2/433 87/18639 0.0229885057471264 0.989567571872263 0.603517299541543 0.768179524228803 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/433 181/18639 0.0220994475138122 0.95129700279433 0.609181228416595 0.768179524228803 GO:0042578 phosphoric ester hydrolase activity 8/433 363/18639 0.0220385674931129 0.94867634989407 0.609701672438723 0.768179524228803 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/433 88/18639 0.0227272727272727 0.97832248582826 0.609751205652498 0.768179524228803 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/433 40/18639 0.025 1.07615473441109 0.609838565928535 0.768179524228803 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/433 40/18639 0.025 1.07615473441109 0.609838565928535 0.768179524228803 GO:0071949 FAD binding 1/433 40/18639 0.025 1.07615473441109 0.609838565928535 0.768179524228803 GO:0016791 phosphatase activity 6/433 273/18639 0.021978021978022 0.94607009618557 0.611442705736454 0.768179524228803 GO:0002020 protease binding 3/433 136/18639 0.0220588235294118 0.949548295068605 0.615337699352014 0.768179524228803 GO:0003727 single-stranded RNA binding 2/433 89/18639 0.0224719101123595 0.967330098347043 0.615910267207122 0.768179524228803 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 5/433 229/18639 0.0218340611353712 0.939873130490031 0.617594410252663 0.768179524228803 GO:0001530 lipopolysaccharide binding 1/433 41/18639 0.024390243902439 1.04990705796203 0.618921844650667 0.768179524228803 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/433 41/18639 0.024390243902439 1.04990705796203 0.618921844650667 0.768179524228803 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/433 41/18639 0.024390243902439 1.04990705796203 0.618921844650667 0.768179524228803 GO:0042169 SH2 domain binding 1/433 41/18639 0.024390243902439 1.04990705796203 0.618921844650667 0.768179524228803 GO:0042287 MHC protein binding 1/433 41/18639 0.024390243902439 1.04990705796203 0.618921844650667 0.768179524228803 GO:0140318 protein transporter activity 1/433 41/18639 0.024390243902439 1.04990705796203 0.618921844650667 0.768179524228803 GO:0140828 metal cation:monoatomic cation antiporter activity 1/433 41/18639 0.024390243902439 1.04990705796203 0.618921844650667 0.768179524228803 GO:0015078 proton transmembrane transporter activity 4/433 185/18639 0.0216216216216216 0.930728418950128 0.626336914821388 0.773775386577696 GO:0004402 histone acetyltransferase activity 1/433 42/18639 0.0238095238095238 1.0249092708677 0.627794134212247 0.773775386577696 GO:0035198 miRNA binding 1/433 42/18639 0.0238095238095238 1.0249092708677 0.627794134212247 0.773775386577696 GO:0046982 protein heterodimerization activity 8/433 369/18639 0.021680216802168 0.933250718188475 0.628052356887761 0.773775386577696 GO:0140101 catalytic activity, acting on a tRNA 3/433 139/18639 0.0215827338129496 0.929054446973599 0.630058875073941 0.773775386577696 GO:0140767 enzyme-substrate adaptor activity 3/433 139/18639 0.0215827338129496 0.929054446973599 0.630058875073941 0.773775386577696 GO:0043178 alcohol binding 2/433 92/18639 0.0217391304347826 0.935786725574857 0.633939610068001 0.773775386577696 GO:0052689 carboxylic ester hydrolase activity 2/433 92/18639 0.0217391304347826 0.935786725574857 0.633939610068001 0.773775386577696 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/433 43/18639 0.0232558139534884 1.0010741715452 0.636460324451861 0.773775386577696 GO:0005245 voltage-gated calcium channel activity 1/433 43/18639 0.0232558139534884 1.0010741715452 0.636460324451861 0.773775386577696 GO:0008200 ion channel inhibitor activity 1/433 43/18639 0.0232558139534884 1.0010741715452 0.636460324451861 0.773775386577696 GO:0008375 acetylglucosaminyltransferase activity 1/433 43/18639 0.0232558139534884 1.0010741715452 0.636460324451861 0.773775386577696 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/433 43/18639 0.0232558139534884 1.0010741715452 0.636460324451861 0.773775386577696 GO:0046943 carboxylic acid transmembrane transporter activity 4/433 188/18639 0.0212765957446809 0.915876369711562 0.638885910131929 0.77510695424584 GO:0051213 dioxygenase activity 2/433 93/18639 0.021505376344086 0.925724502719213 0.639800689430242 0.77510695424584 GO:0005342 organic acid transmembrane transporter activity 4/433 189/18639 0.0211640211640212 0.911030462993512 0.643007544553523 0.77510695424584 GO:0016248 channel inhibitor activity 1/433 44/18639 0.0227272727272727 0.97832248582826 0.644925192139124 0.77510695424584 GO:0016790 thiolester hydrolase activity 1/433 44/18639 0.0227272727272727 0.97832248582826 0.644925192139124 0.77510695424584 GO:0019205 nucleobase-containing compound kinase activity 1/433 44/18639 0.0227272727272727 0.97832248582826 0.644925192139124 0.77510695424584 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/433 44/18639 0.0227272727272727 0.97832248582826 0.644925192139124 0.77510695424584 GO:0016410 N-acyltransferase activity 2/433 94/18639 0.0212765957446809 0.915876369711562 0.645587787020823 0.77510695424584 GO:0008009 chemokine activity 1/433 45/18639 0.0222222222222222 0.956581986143187 0.653193403583263 0.779389965326551 GO:0046915 transition metal ion transmembrane transporter activity 1/433 45/18639 0.0222222222222222 0.956581986143187 0.653193403583263 0.779389965326551 GO:0051539 4 iron, 4 sulfur cluster binding 1/433 45/18639 0.0222222222222222 0.956581986143187 0.653193403583263 0.779389965326551 GO:0141110 transporter inhibitor activity 1/433 45/18639 0.0222222222222222 0.956581986143187 0.653193403583263 0.779389965326551 GO:0016407 acetyltransferase activity 2/433 96/18639 0.0208333333333333 0.896795612009238 0.656941127821337 0.782652084379741 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/433 46/18639 0.0217391304347826 0.935786725574857 0.661269517181652 0.785384718868054 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/433 46/18639 0.0217391304347826 0.935786725574857 0.661269517181652 0.785384718868054 GO:0015085 calcium ion transmembrane transporter activity 3/433 147/18639 0.0204081632653061 0.878493660743743 0.667386969641305 0.789892913031006 GO:0001784 phosphotyrosine residue binding 1/433 47/18639 0.0212765957446809 0.915876369711562 0.669157985909686 0.789892913031006 GO:0061733 protein-lysine-acetyltransferase activity 1/433 47/18639 0.0212765957446809 0.915876369711562 0.669157985909686 0.789892913031006 GO:0140359 ABC-type transporter activity 1/433 47/18639 0.0212765957446809 0.915876369711562 0.669157985909686 0.789892913031006 GO:0008509 monoatomic anion transmembrane transporter activity 3/433 149/18639 0.0201342281879195 0.866701799525706 0.676278191827026 0.795210003531818 GO:0032266 phosphatidylinositol-3-phosphate binding 1/433 48/18639 0.0208333333333333 0.896795612009238 0.676863159753334 0.795210003531818 GO:0038187 pattern recognition receptor activity 1/433 48/18639 0.0208333333333333 0.896795612009238 0.676863159753334 0.795210003531818 GO:0005261 monoatomic cation channel activity 7/433 341/18639 0.0205278592375367 0.883646116231976 0.68199158675724 0.795210003531818 GO:0042393 histone binding 5/433 247/18639 0.0202429149797571 0.871380351749867 0.683002739413027 0.795210003531818 GO:0001222 transcription corepressor binding 1/433 49/18639 0.0204081632653061 0.878493660743743 0.684389288085689 0.795210003531818 GO:0035254 glutamate receptor binding 1/433 49/18639 0.0204081632653061 0.878493660743743 0.684389288085689 0.795210003531818 GO:0000510 H3-H4 histone complex chaperone activity 3/433 151/18639 0.0198675496688742 0.855222305492253 0.684993072990491 0.795210003531818 GO:0140584 chromatin extrusion motor activity 3/433 151/18639 0.0198675496688742 0.855222305492253 0.684993072990491 0.795210003531818 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/433 151/18639 0.0198675496688742 0.855222305492253 0.684993072990491 0.795210003531818 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/433 151/18639 0.0198675496688742 0.855222305492253 0.684993072990491 0.795210003531818 GO:0015171 amino acid transmembrane transporter activity 2/433 102/18639 0.0196078431372549 0.844042928949871 0.689258562661528 0.795407518971704 GO:0015616 DNA translocase activity 3/433 152/18639 0.0197368421052632 0.84959584295612 0.689284495067448 0.795407518971704 GO:0046906 tetrapyrrole binding 3/433 152/18639 0.0197368421052632 0.84959584295612 0.689284495067448 0.795407518971704 GO:0140674 ATP-dependent histone chaperone activity 3/433 152/18639 0.0197368421052632 0.84959584295612 0.689284495067448 0.795407518971704 GO:0032813 tumor necrosis factor receptor superfamily binding 1/433 50/18639 0.02 0.860923787528868 0.691740521988804 0.797050273097547 GO:0061775 cohesin loader activity 3/433 153/18639 0.0196078431372549 0.844042928949871 0.693531988507317 0.797727367832228 GO:0005253 monoatomic anion channel activity 2/433 103/18639 0.0194174757281553 0.835848337406668 0.694394807232199 0.797727367832228 GO:0005506 iron ion binding 3/433 154/18639 0.0194805194805195 0.838562130709937 0.697735631234333 0.799358440822276 GO:0003743 translation initiation factor activity 1/433 51/18639 0.0196078431372549 0.844042928949871 0.698920916522068 0.799358440822276 GO:0005048 signal sequence binding 1/433 51/18639 0.0196078431372549 0.844042928949871 0.698920916522068 0.799358440822276 GO:0008168 methyltransferase activity 4/433 204/18639 0.0196078431372549 0.844042928949871 0.701074482519946 0.800283051411307 GO:0004386 helicase activity 3/433 155/18639 0.0193548387096774 0.833152052447292 0.701895512821532 0.800283051411307 GO:0005080 protein kinase C binding 1/433 52/18639 0.0192307692307692 0.827811334162374 0.705934432938355 0.800283051411307 GO:0030159 signaling receptor complex adaptor activity 1/433 52/18639 0.0192307692307692 0.827811334162374 0.705934432938355 0.800283051411307 GO:0000149 SNARE binding 2/433 106/18639 0.0188679245283019 0.812192252385725 0.70938402698218 0.800283051411307 GO:0008013 beta-catenin binding 2/433 106/18639 0.0188679245283019 0.812192252385725 0.70938402698218 0.800283051411307 GO:0005516 calmodulin binding 4/433 207/18639 0.0193236714975845 0.831810422733206 0.71183382180959 0.800283051411307 GO:0005246 calcium channel regulator activity 1/433 53/18639 0.0188679245283019 0.812192252385725 0.712784940849136 0.800283051411307 GO:0008146 sulfotransferase activity 1/433 53/18639 0.0188679245283019 0.812192252385725 0.712784940849136 0.800283051411307 GO:0016860 intramolecular oxidoreductase activity 1/433 53/18639 0.0188679245283019 0.812192252385725 0.712784940849136 0.800283051411307 GO:0034212 protein N-acetyltransferase activity 1/433 53/18639 0.0188679245283019 0.812192252385725 0.712784940849136 0.800283051411307 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/433 53/18639 0.0188679245283019 0.812192252385725 0.712784940849136 0.800283051411307 GO:0140658 ATP-dependent chromatin remodeler activity 3/433 158/18639 0.0189873417721519 0.817332709679305 0.714113653184211 0.800283051411307 GO:0019888 protein phosphatase regulator activity 2/433 107/18639 0.0186915887850467 0.804601670587727 0.714242257023822 0.800283051411307 GO:0005216 monoatomic ion channel activity 9/433 448/18639 0.0200892857142857 0.864767197294622 0.717080618488189 0.800339541934118 GO:0003712 transcription coregulator activity 10/433 495/18639 0.0202020202020202 0.869619987402897 0.717325040728448 0.800339541934118 GO:0005496 steroid binding 2/433 108/18639 0.0185185185185185 0.797151655119323 0.719032265307435 0.800339541934118 GO:0017069 snRNA binding 1/433 54/18639 0.0185185185185185 0.797151655119323 0.719476220339738 0.800339541934118 GO:0140463 chromatin-protein adaptor activity 1/433 54/18639 0.0185185185185185 0.797151655119323 0.719476220339738 0.800339541934118 GO:0003689 DNA clamp loader activity 3/433 160/18639 0.01875 0.807116050808314 0.722042406289473 0.802038471446723 GO:0005178 integrin binding 3/433 161/18639 0.0186335403726708 0.802102907635592 0.72594220685224 0.802981713804732 GO:0008374 O-acyltransferase activity 1/433 55/18639 0.0181818181818182 0.782657988662608 0.726011964035885 0.802981713804732 GO:0098632 cell-cell adhesion mediator activity 1/433 55/18639 0.0181818181818182 0.782657988662608 0.726011964035885 0.802981713804732 GO:0004222 metalloendopeptidase activity 2/433 110/18639 0.0181818181818182 0.782657988662608 0.728409786122878 0.804481194401806 GO:0008083 growth factor activity 3/433 162/18639 0.0185185185185185 0.797151655119323 0.729799168042073 0.8048642253264 GO:0016741 transferase activity, transferring one-carbon groups 4/433 215/18639 0.0186046511627907 0.800859337236157 0.739134786570373 0.813997225723721 GO:0015103 inorganic anion transmembrane transporter activity 3/433 165/18639 0.0181818181818182 0.782657988662608 0.741114752331133 0.815015083760164 GO:0061980 regulatory RNA binding 1/433 58/18639 0.0172413793103448 0.742175678904197 0.744721636794348 0.816743249099892 GO:0015399 primary active transmembrane transporter activity 3/433 166/18639 0.0180722891566265 0.777943181501989 0.744802133894202 0.816743249099892 GO:0016874 ligase activity 3/433 167/18639 0.0179640718562874 0.773284839097786 0.748447604818823 0.819576667971817 GO:0015459 potassium channel regulator activity 1/433 59/18639 0.0169491525423729 0.72959643010921 0.750670484072108 0.819716379697519 GO:0017124 SH3 domain binding 2/433 115/18639 0.0173913043478261 0.748629380459885 0.750698808868065 0.819716379697519 GO:0008514 organic anion transmembrane transporter activity 5/433 269/18639 0.0185873605947955 0.800115044171811 0.752145550115077 0.82013610831757 GO:0004857 enzyme inhibitor activity 8/433 416/18639 0.0192307692307692 0.827811334162374 0.75406468676457 0.821069024234483 GO:0019208 phosphatase regulator activity 2/433 117/18639 0.0170940170940171 0.735832297033221 0.75916488505001 0.825458156702265 GO:0019905 syntaxin binding 1/433 61/18639 0.0163934426229508 0.7056752356794 0.762156440797593 0.827545390008076 GO:0022853 active monoatomic ion transmembrane transporter activity 2/433 118/18639 0.0169491525423729 0.72959643010921 0.763304027900447 0.827627401038125 GO:0008017 microtubule binding 5/433 276/18639 0.0181159420289855 0.779822271312381 0.771631567894681 0.835077354232161 GO:0005507 copper ion binding 1/433 63/18639 0.0158730158730159 0.683272847245134 0.773114435299962 0.835077354232161 GO:0061134 peptidase regulator activity 4/433 226/18639 0.0176991150442478 0.761879457990149 0.773420088440408 0.835077354232161 GO:0022832 voltage-gated channel activity 3/433 175/18639 0.0171428571428571 0.737934675024744 0.776128989683075 0.836831815691808 GO:0004536 DNA nuclease activity 1/433 64/18639 0.015625 0.672596709006928 0.77840305768988 0.838113194611698 GO:0019843 rRNA binding 1/433 65/18639 0.0153846153846154 0.662249067329899 0.783568682240097 0.842500031600773 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/433 67/18639 0.0149253731343284 0.642480438454379 0.793542288146949 0.849673573438896 GO:0042054 histone methyltransferase activity 1/433 67/18639 0.0149253731343284 0.642480438454379 0.793542288146949 0.849673573438896 GO:0050840 extracellular matrix binding 1/433 67/18639 0.0149253731343284 0.642480438454379 0.793542288146949 0.849673573438896 GO:0004519 endonuclease activity 2/433 127/18639 0.015748031496063 0.677892746085723 0.797852904913785 0.85246288095514 GO:0030145 manganese ion binding 1/433 68/18639 0.0147058823529412 0.633032196712403 0.798355780998143 0.85246288095514 GO:0016279 protein-lysine N-methyltransferase activity 1/433 69/18639 0.0144927536231884 0.623857817049905 0.803057302016279 0.856298670105756 GO:0008237 metallopeptidase activity 3/433 184/18639 0.016304347826087 0.701840044181143 0.804233871880411 0.856370412540244 GO:1901981 phosphatidylinositol phosphate binding 3/433 185/18639 0.0162162162162162 0.698046314212596 0.80716623930446 0.856463427756918 GO:0016278 lysine N-methyltransferase activity 1/433 70/18639 0.0142857142857143 0.61494556252062 0.807649450009114 0.856463427756918 GO:0016782 transferase activity, transferring sulphur-containing groups 1/433 70/18639 0.0142857142857143 0.61494556252062 0.807649450009114 0.856463427756918 GO:0005543 phospholipid binding 9/433 497/18639 0.0181086519114688 0.779508459533181 0.819661051327212 0.868008685356114 GO:0003678 DNA helicase activity 1/433 74/18639 0.0135135135135135 0.58170526184383 0.824974210548537 0.870054768502009 GO:0003684 damaged DNA binding 1/433 74/18639 0.0135135135135135 0.58170526184383 0.824974210548537 0.870054768502009 GO:0035064 methylated histone binding 1/433 74/18639 0.0135135135135135 0.58170526184383 0.824974210548537 0.870054768502009 GO:0019838 growth factor binding 2/433 136/18639 0.0147058823529412 0.633032196712403 0.827865689431189 0.871846869514817 GO:0033218 amide binding 4/433 247/18639 0.0161943319838057 0.697104281399893 0.828932127232999 0.871846869514817 GO:0098631 cell adhesion mediator activity 1/433 76/18639 0.0131578947368421 0.566397228637413 0.833043627482931 0.873790326653292 GO:0140034 methylation-dependent protein binding 1/433 76/18639 0.0131578947368421 0.566397228637413 0.833043627482931 0.873790326653292 GO:0015370 solute:sodium symporter activity 1/433 79/18639 0.0126582278481013 0.544888473119537 0.844457082028208 0.884542981838314 GO:0020037 heme binding 2/433 142/18639 0.0140845070422535 0.606284357414696 0.845586425643362 0.884542981838314 GO:0022843 voltage-gated monoatomic cation channel activity 2/433 143/18639 0.013986013986014 0.602044606663544 0.848373820688865 0.886257901991616 GO:0003714 transcription corepressor activity 3/433 204/18639 0.0147058823529412 0.633032196712403 0.856192521967133 0.893217063457604 GO:0008135 translation factor activity, RNA binding 1/433 83/18639 0.0120481927710843 0.518628787667993 0.858473182970682 0.894387715591588 GO:0003730 mRNA 3'-UTR binding 4/433 262/18639 0.0152671755725191 0.657193730938067 0.861277225829194 0.895411606997114 GO:0180051 translation factor activity 1/433 84/18639 0.0119047619047619 0.51245463543385 0.861775678754994 0.895411606997114 GO:0050660 flavin adenine dinucleotide binding 1/433 86/18639 0.0116279069767442 0.500537085772598 0.868151788969444 0.900738817975308 GO:0008094 ATP-dependent activity, acting on DNA 3/433 210/18639 0.0142857142857143 0.61494556252062 0.86923629454871 0.900738817975308 GO:0016757 glycosyltransferase activity 4/433 267/18639 0.0149812734082397 0.644886732231362 0.870833822133768 0.9011845987765 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/433 91/18639 0.010989010989011 0.473035048092785 0.882837429682685 0.912383528400311 GO:0008276 protein methyltransferase activity 1/433 95/18639 0.0105263157894737 0.453117782909931 0.893401636661453 0.921070510881143 GO:0140097 catalytic activity, acting on DNA 5/433 336/18639 0.0148809523809524 0.640568294292313 0.893629290997378 0.921070510881143 GO:0005249 voltage-gated potassium channel activity 1/433 98/18639 0.0102040816326531 0.439246830371872 0.900696194276885 0.924650880294888 GO:0008170 N-methyltransferase activity 1/433 98/18639 0.0102040816326531 0.439246830371872 0.900696194276885 0.924650880294888 GO:0042626 ATPase-coupled transmembrane transporter activity 1/433 98/18639 0.0102040816326531 0.439246830371872 0.900696194276885 0.924650880294888 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/433 167/18639 0.0119760479041916 0.515523226065191 0.902899618212286 0.925681945896261 GO:0005244 voltage-gated monoatomic ion channel activity 2/433 173/18639 0.0115606936416185 0.497643807820155 0.913337364308406 0.935141174066432 GO:0004497 monooxygenase activity 1/433 106/18639 0.00943396226415094 0.406096126192862 0.917804344949209 0.938470138146741 GO:0061135 endopeptidase regulator activity 2/433 184/18639 0.0108695652173913 0.467893362787428 0.929794987450804 0.949473188243413 GO:0022836 gated channel activity 4/433 318/18639 0.0125786163522013 0.541461501590483 0.939977027959917 0.958602728646045 GO:0016758 hexosyltransferase activity 2/433 197/18639 0.0101522842639594 0.437017151029882 0.94544082889031 0.962902796706225 GO:0016298 lipase activity 1/433 130/18639 0.00769230769230769 0.331124533664949 0.953411107810073 0.968464967407074 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/433 130/18639 0.00769230769230769 0.331124533664949 0.953411107810073 0.968464967407074 GO:0051015 actin filament binding 2/433 209/18639 0.00956937799043062 0.411925257190846 0.956891593727914 0.970723141074835 GO:0099094 ligand-gated monoatomic cation channel activity 1/433 136/18639 0.00735294117647059 0.316516098356202 0.959580567233345 0.972173488063179 GO:0035091 phosphatidylinositol binding 3/433 284/18639 0.0105633802816901 0.454713268061022 0.962554393937021 0.973908246552267 GO:0008194 UDP-glycosyltransferase activity 1/433 145/18639 0.00689655172413793 0.296870271561679 0.96734016440919 0.977469380790438 GO:0004866 endopeptidase inhibitor activity 1/433 161/18639 0.0062111801242236 0.267367635878531 0.977647740712377 0.986593537032621 GO:0005201 extracellular matrix structural constituent 1/433 168/18639 0.00595238095238095 0.256227317716925 0.981066842586903 0.987909051235657 GO:0030414 peptidase inhibitor activity 1/433 169/18639 0.00591715976331361 0.254711179742269 0.981510676551489 0.987909051235657 GO:0015276 ligand-gated monoatomic ion channel activity 1/433 186/18639 0.00537634408602151 0.231431125679803 0.987649055419846 0.992077122522687 GO:0022834 ligand-gated channel activity 1/433 188/18639 0.00531914893617021 0.228969092427891 0.988221900543972 0.992077122522687 GO:0003779 actin binding 4/433 443/18639 0.0090293453724605 0.388678910848248 0.992674776063702 0.995253152105426 GO:0005539 glycosaminoglycan binding 1/433 242/18639 0.00413223140495868 0.177876815605138 0.996739046767425 0.998031834117318 GO:0004984 olfactory receptor activity 1/433 419/18639 0.00238663484486874 0.102735535504638 0.999952843391211 0.999952843391211