ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0046332 SMAD binding 16/1034 79/18639 0.20253164556962 3.6508581641897 5.67258660994135e-06 0.00401891327663869 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 11/1034 40/18639 0.275 4.95718085106383 7.58285523894092e-06 0.00401891327663869 GO:0140297 DNA-binding transcription factor binding 49/1034 488/18639 0.100409836065574 1.80999896946444 4.36367521398686e-05 0.0154183190894202 GO:0031072 heat shock protein binding 19/1034 131/18639 0.145038167938931 2.61447428647364 0.00011159025127484 0.0295714165878325 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 6/1034 17/18639 0.352941176470588 6.36215724200706 0.000209402915753089 0.0443934181396549 GO:0003779 actin binding 43/1034 443/18639 0.0970654627539503 1.7497129209583 0.000264504388426748 0.0460557795103032 GO:0030695 GTPase regulator activity 46/1034 489/18639 0.0940695296523517 1.69570789476807 0.000332263742297388 0.0460557795103032 GO:0060589 nucleoside-triphosphatase regulator activity 46/1034 490/18639 0.0938775510204082 1.6922472664114 0.000347590788757006 0.0460557795103032 GO:0003712 transcription coregulator activity 46/1034 495/18639 0.0929292929292929 1.67515385967997 0.000434153937136182 0.0501883187969771 GO:0106310 protein serine kinase activity 36/1034 361/18639 0.0997229916897507 1.79761783569174 0.000492486189806403 0.0501883187969771 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 35/1034 349/18639 0.100286532951289 1.8077762936935 0.000528605991389906 0.0501883187969771 GO:0016505 peptidase activator activity involved in apoptotic process 6/1034 20/18639 0.3 5.407833655706 0.000568169646758232 0.0501883187969771 GO:0001217 DNA-binding transcription repressor activity 29/1034 278/18639 0.10431654676259 1.88042177476587 0.000827230662640324 0.0595242806981654 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 7/1034 29/18639 0.241379310344828 4.35113052757954 0.000842324726860832 0.0595242806981654 GO:0097472 cyclin-dependent protein kinase activity 7/1034 29/18639 0.241379310344828 4.35113052757954 0.000842324726860832 0.0595242806981654 GO:0032182 ubiquitin-like protein binding 16/1034 120/18639 0.133333333333333 2.40348162475822 0.000970328665509248 0.0619936446525271 GO:0033691 sialic acid binding 6/1034 22/18639 0.272727272727273 4.91621241427818 0.000994237697257511 0.0619936446525271 GO:0004674 protein serine/threonine kinase activity 40/1034 433/18639 0.092378752886836 1.66522976311193 0.00111774635964607 0.0634520123212327 GO:0038187 pattern recognition receptor activity 9/1034 48/18639 0.1875 3.37989603481625 0.0011373473906636 0.0634520123212327 GO:0043130 ubiquitin binding 14/1034 100/18639 0.14 2.52365570599613 0.001222503747871 0.064792698637163 GO:0071723 lipopeptide binding 4/1034 10/18639 0.4 7.21044487427466 0.00150992935163948 0.0674475797923956 GO:0016922 nuclear receptor binding 17/1034 137/18639 0.124087591240876 2.23681684055966 0.00153636813982904 0.0674475797923956 GO:0061650 ubiquitin-like protein conjugating enzyme activity 8/1034 41/18639 0.195121951219512 3.51729018257301 0.00162292862663239 0.0674475797923956 GO:0035035 histone acetyltransferase binding 6/1034 24/18639 0.25 4.50652804642166 0.00163075113957369 0.0674475797923956 GO:0017124 SH3 domain binding 15/1034 115/18639 0.130434782608696 2.35123202422 0.00172535722093121 0.0674475797923956 GO:0042826 histone deacetylase binding 16/1034 127/18639 0.125984251968504 2.27100625961407 0.00177903549912712 0.0674475797923956 GO:0008429 phosphatidylethanolamine binding 5/1034 17/18639 0.294117647058824 5.30179770167255 0.00183845903320683 0.0674475797923956 GO:0019894 kinesin binding 8/1034 42/18639 0.19047619047619 3.43354517822603 0.00190889376770931 0.0674475797923956 GO:0048487 beta-tubulin binding 8/1034 42/18639 0.19047619047619 3.43354517822603 0.00190889376770931 0.0674475797923956 GO:0051879 Hsp90 protein binding 8/1034 42/18639 0.19047619047619 3.43354517822603 0.00190889376770931 0.0674475797923956 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 27/1034 268/18639 0.100746268656716 1.8160635410953 0.0020401178088535 0.0697588670124099 GO:0001223 transcription coactivator binding 8/1034 44/18639 0.181818181818182 3.27747494285212 0.00259902295271387 0.0825269704112837 GO:0061631 ubiquitin conjugating enzyme activity 7/1034 35/18639 0.2 3.60522243713733 0.00271475144637697 0.0825269704112837 GO:0019207 kinase regulator activity 28/1034 287/18639 0.0975609756097561 1.7586450912865 0.0027189411817514 0.0825269704112837 GO:0003725 double-stranded RNA binding 11/1034 75/18639 0.146666666666667 2.64382978723404 0.00272494713622163 0.0825269704112837 GO:0015631 tubulin binding 35/1034 385/18639 0.0909090909090909 1.63873747142606 0.00287795873357682 0.0847398960442062 GO:0016504 peptidase activator activity 9/1034 57/18639 0.157894736842105 2.84622823984526 0.00390802281229356 0.0902956508806882 GO:0043021 ribonucleoprotein complex binding 19/1034 177/18639 0.107344632768362 1.93500639281382 0.00447919663119785 0.0902956508806882 GO:0035325 Toll-like receptor binding 4/1034 13/18639 0.307692307692308 5.54649605713436 0.004497171683581 0.0902956508806882 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 24/1034 243/18639 0.0987654320987654 1.78035675908016 0.00451049632880572 0.0902956508806882 GO:0031490 chromatin DNA binding 15/1034 128/18639 0.1171875 2.11243502176015 0.00488759186835636 0.0902956508806882 GO:0004676 3-phosphoinositide-dependent protein kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:0004711 ribosomal protein S6 kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:0035175 histone H3S10 kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:0035979 histone H2AXS139 kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:0044022 histone H3S28 kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:0044023 histone H4S1 kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:0044024 histone H2AS1 kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:0044025 histone H2BS14 kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:0072354 histone H3T3 kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:0072371 histone H2AS121 kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:0072518 Rho-dependent protein serine/threonine kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:0140823 histone H2BS36 kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:0140855 histone H3S57 kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:0140995 histone H2A kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:0140997 histone H4 kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:0140998 histone H2B kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:1990244 histone H2AT120 kinase activity 24/1034 245/18639 0.0979591836734694 1.76582323451624 0.00499526037138263 0.0902956508806882 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 5/1034 21/18639 0.238095238095238 4.29193147278254 0.00502589000184963 0.0902956508806882 GO:0004677 DNA-dependent protein kinase activity 24/1034 246/18639 0.0975609756097561 1.7586450912865 0.00525344183872431 0.0912893171975044 GO:0140857 histone H3T45 kinase activity 24/1034 246/18639 0.0975609756097561 1.7586450912865 0.00525344183872431 0.0912893171975044 GO:0035402 histone H3T11 kinase activity 24/1034 247/18639 0.097165991902834 1.75152507067401 0.00552261234298197 0.0929201441835062 GO:0035403 histone H3T6 kinase activity 24/1034 247/18639 0.097165991902834 1.75152507067401 0.00552261234298197 0.0929201441835062 GO:0004679 AMP-activated protein kinase activity 24/1034 248/18639 0.0967741935483871 1.74446246958258 0.00580312159514529 0.0961142014195939 GO:0071933 Arp2/3 complex binding 4/1034 14/18639 0.285714285714286 5.15031776733904 0.00602255705558985 0.0982140073680806 GO:0019903 protein phosphatase binding 16/1034 144/18639 0.111111111111111 2.00290135396518 0.00625568310833539 0.100470062042962 GO:0004860 protein kinase inhibitor activity 11/1034 84/18639 0.130952380952381 2.3605623100304 0.00658231203615692 0.104138071019796 GO:0051082 unfolded protein binding 14/1034 121/18639 0.115702479338843 2.08566587272408 0.00717500269847839 0.11184563029981 GO:0050700 CARD domain binding 4/1034 15/18639 0.266666666666667 4.80696324951644 0.00785659331519665 0.120695491508818 GO:0019887 protein kinase regulator activity 24/1034 255/18639 0.0941176470588235 1.69657526453521 0.00811478828478862 0.122881079741085 GO:0044183 protein folding chaperone 10/1034 75/18639 0.133333333333333 2.40348162475822 0.00825567254821324 0.123253702832479 GO:0140416 transcription regulator inhibitor activity 6/1034 33/18639 0.181818181818182 3.27747494285212 0.00877108579833312 0.129129874253238 GO:0005085 guanyl-nucleotide exchange factor activity 22/1034 230/18639 0.0956521739130435 1.72423681776133 0.00914388788660553 0.132774262463039 GO:0019902 phosphatase binding 19/1034 190/18639 0.1 1.80261121856867 0.00944314419150808 0.135266660040521 GO:0003714 transcription corepressor activity 20/1034 204/18639 0.0980392156862745 1.76726590055752 0.00971858175708461 0.137355955500129 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 4/1034 16/18639 0.25 4.50652804642166 0.010022349459924 0.138251604084947 GO:0043014 alpha-tubulin binding 7/1034 44/18639 0.159090909090909 2.8677905749956 0.0100428052023971 0.138251604084947 GO:0017025 TBP-class protein binding 5/1034 25/18639 0.2 3.60522243713733 0.0109217807022555 0.146662704308713 GO:0019210 kinase inhibitor activity 11/1034 90/18639 0.122222222222222 2.2031914893617 0.0109305223022531 0.146662704308713 GO:0001221 transcription coregulator binding 13/1034 115/18639 0.11304347826087 2.03773442099066 0.0112889721336097 0.149578880770328 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 14/1034 128/18639 0.109375 1.97160602030948 0.0115588224846228 0.151263602885187 GO:0051787 misfolded protein binding 4/1034 17/18639 0.235294117647059 4.24143816133804 0.0125404695912216 0.162108509349938 GO:0005112 Notch binding 5/1034 26/18639 0.192307692307692 3.46656003570897 0.0129181890054528 0.164979281274457 GO:0005522 profilin binding 3/1034 10/18639 0.3 5.407833655706 0.015226277801681 0.183565954379277 GO:0005528 FK506 binding 3/1034 10/18639 0.3 5.407833655706 0.015226277801681 0.183565954379277 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 3/1034 10/18639 0.3 5.407833655706 0.015226277801681 0.183565954379277 GO:0050308 sugar-phosphatase activity 3/1034 10/18639 0.3 5.407833655706 0.015226277801681 0.183565954379277 GO:0000900 mRNA regulatory element binding translation repressor activity 4/1034 18/18639 0.222222222222222 4.00580270793037 0.0154290617285798 0.183565954379277 GO:0050811 GABA receptor binding 4/1034 18/18639 0.222222222222222 4.00580270793037 0.0154290617285798 0.183565954379277 GO:0070063 RNA polymerase binding 8/1034 59/18639 0.135593220338983 2.44421860144904 0.0156899641783392 0.183565954379277 GO:0003713 transcription coactivator activity 23/1034 256/18639 0.08984375 1.61953351668279 0.0157589640080323 0.183565954379277 GO:0019787 ubiquitin-like protein transferase activity 38/1034 479/18639 0.0793319415448852 1.43004647819644 0.0171124677818628 0.197165389660593 GO:0019789 SUMO transferase activity 5/1034 28/18639 0.178571428571429 3.2189486045869 0.0176190799990643 0.198975277806254 GO:0016763 pentosyltransferase activity 7/1034 49/18639 0.142857142857143 2.57515888366952 0.0177408629276624 0.198975277806254 GO:0016755 aminoacyltransferase activity 39/1034 496/18639 0.0786290322580645 1.41737575653585 0.018059817684774 0.198975277806254 GO:0042834 peptidoglycan binding 4/1034 19/18639 0.210526315789474 3.79497098646035 0.018703637162011 0.198975277806254 GO:0002020 protease binding 14/1034 136/18639 0.102941176470588 1.85562919558539 0.0188592620667381 0.198975277806254 GO:0016779 nucleotidyltransferase activity 14/1034 136/18639 0.102941176470588 1.85562919558539 0.0188592620667381 0.198975277806254 GO:0044325 transmembrane transporter binding 14/1034 136/18639 0.102941176470588 1.85562919558539 0.0188592620667381 0.198975277806254 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 6/1034 39/18639 0.153846153846154 2.77324802856718 0.0195141986670366 0.198975277806254 GO:0008017 microtubule binding 24/1034 276/18639 0.0869565217391304 1.56748801614667 0.0198490462213636 0.198975277806254 GO:0015173 aromatic amino acid transmembrane transporter activity 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.198975277806254 GO:0019203 carbohydrate phosphatase activity 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.198975277806254 GO:0047676 arachidonate-CoA ligase activity 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.198975277806254 GO:0050786 RAGE receptor binding 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.198975277806254 GO:0070990 snRNP binding 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.198975277806254 GO:0140537 transcription regulator activator activity 3/1034 11/18639 0.272727272727273 4.91621241427818 0.0200852403068577 0.198975277806254 GO:0044389 ubiquitin-like protein ligase binding 27/1034 322/18639 0.0838509316770186 1.51150630128428 0.0216211457061092 0.212207541189591 GO:0042288 MHC class I protein binding 4/1034 20/18639 0.2 3.60522243713733 0.0223770926386726 0.217612093550394 GO:0019003 GDP binding 9/1034 75/18639 0.12 2.1631334622824 0.0225954986718396 0.217738441746818 GO:0030246 carbohydrate binding 24/1034 280/18639 0.0857142857142857 1.54509533020171 0.0231320426360786 0.218840239148629 GO:0031624 ubiquitin conjugating enzyme binding 5/1034 30/18639 0.166666666666667 3.00435203094778 0.0233291953054671 0.218840239148629 GO:0070566 adenylyltransferase activity 5/1034 30/18639 0.166666666666667 3.00435203094778 0.0233291953054671 0.218840239148629 GO:0140318 protein transporter activity 6/1034 41/18639 0.146341463414634 2.63796763692975 0.0245042991752669 0.225099169085329 GO:0003727 single-stranded RNA binding 10/1034 89/18639 0.112359550561798 2.0254058635603 0.0254110079295402 0.225099169085329 GO:0005095 GTPase inhibitor activity 3/1034 12/18639 0.25 4.50652804642166 0.025695282508797 0.225099169085329 GO:0005527 macrolide binding 3/1034 12/18639 0.25 4.50652804642166 0.025695282508797 0.225099169085329 GO:0035259 nuclear glucocorticoid receptor binding 3/1034 12/18639 0.25 4.50652804642166 0.025695282508797 0.225099169085329 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 3/1034 12/18639 0.25 4.50652804642166 0.025695282508797 0.225099169085329 GO:0097677 STAT family protein binding 3/1034 12/18639 0.25 4.50652804642166 0.025695282508797 0.225099169085329 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/1034 12/18639 0.25 4.50652804642166 0.025695282508797 0.225099169085329 GO:0019200 carbohydrate kinase activity 4/1034 21/18639 0.19047619047619 3.43354517822603 0.0264597285532192 0.229896002183708 GO:0005096 GTPase activator activity 23/1034 271/18639 0.0848708487084871 1.52989144011363 0.0284679055716636 0.245333169967182 GO:0003925 G protein activity 7/1034 54/18639 0.12962962962963 2.33671824629271 0.0288643120979032 0.246743313094979 GO:0022884 macromolecule transmembrane transporter activity 5/1034 32/18639 0.15625 2.81658002901354 0.0301136676412872 0.255363901598115 GO:0140517 protein-RNA adaptor activity 4/1034 22/18639 0.181818181818182 3.27747494285212 0.0309592971002823 0.260451229573803 GO:0000287 magnesium ion binding 20/1034 230/18639 0.0869565217391304 1.56748801614667 0.0314090136142058 0.262153971898096 GO:0015651 quaternary ammonium group transmembrane transporter activity 3/1034 13/18639 0.230769230769231 4.15987204285077 0.0320547157563618 0.265453114857371 GO:0051219 phosphoprotein binding 10/1034 93/18639 0.10752688172043 1.93829163286953 0.0331999008430178 0.272805386772084 GO:0043177 organic acid binding 17/1034 189/18639 0.0899470899470899 1.62139633416229 0.0340387974825994 0.277547117935041 GO:0030170 pyridoxal phosphate binding 7/1034 56/18639 0.125 2.25326402321083 0.0343966224914546 0.278323815579709 GO:0015101 organic cation transmembrane transporter activity 9/1034 81/18639 0.111111111111111 2.00290135396518 0.0350920336889212 0.28179966447164 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 4/1034 23/18639 0.173913043478261 3.13497603229333 0.0358810750587931 0.285969470393389 GO:0046915 transition metal ion transmembrane transporter activity 6/1034 45/18639 0.133333333333333 2.40348162475822 0.0368821623217744 0.291754418366275 GO:0070279 vitamin B6 binding 7/1034 57/18639 0.12280701754386 2.2137330754352 0.0374093258272677 0.293732484273361 GO:0005161 platelet-derived growth factor receptor binding 3/1034 14/18639 0.214285714285714 3.86273832550428 0.0391543954020269 0.302946416979187 GO:0044548 S100 protein binding 3/1034 14/18639 0.214285714285714 3.86273832550428 0.0391543954020269 0.302946416979187 GO:0061659 ubiquitin-like protein ligase activity 29/1034 372/18639 0.0779569892473118 1.40526143383041 0.0410626498483046 0.315408759704369 GO:0016757 glycosyltransferase activity 22/1034 267/18639 0.0823970037453183 1.48529763327755 0.0417404888864059 0.318308764169714 GO:0005154 epidermal growth factor receptor binding 5/1034 35/18639 0.142857142857143 2.57515888366952 0.0424083137298952 0.321091518240635 GO:0004879 nuclear receptor activity 7/1034 59/18639 0.11864406779661 2.13869127626791 0.0439423454304579 0.330346710328265 GO:0070851 growth factor receptor binding 13/1034 139/18639 0.0935251798561151 1.68589538427285 0.0452650688730917 0.332747072659699 GO:0004467 long-chain fatty acid-CoA ligase activity 3/1034 15/18639 0.2 3.60522243713733 0.0469788459237345 0.332747072659699 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 3/1034 15/18639 0.2 3.60522243713733 0.0469788459237345 0.332747072659699 GO:0004709 MAP kinase kinase kinase activity 4/1034 25/18639 0.16 2.88417794970986 0.0470005614359583 0.332747072659699 GO:0008139 nuclear localization sequence binding 4/1034 25/18639 0.16 2.88417794970986 0.0470005614359583 0.332747072659699 GO:0015662 P-type ion transporter activity 4/1034 25/18639 0.16 2.88417794970986 0.0470005614359583 0.332747072659699 GO:0120020 cholesterol transfer activity 4/1034 25/18639 0.16 2.88417794970986 0.0470005614359583 0.332747072659699 GO:0140358 P-type transmembrane transporter activity 4/1034 25/18639 0.16 2.88417794970986 0.0470005614359583 0.332747072659699 GO:0044390 ubiquitin-like protein conjugating enzyme binding 5/1034 36/18639 0.138888888888889 2.50362669245648 0.0470868499046744 0.332747072659699 GO:0098531 ligand-modulated transcription factor activity 7/1034 60/18639 0.116666666666667 2.10304642166344 0.0474675382090889 0.33321583113665 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 6/1034 48/18639 0.125 2.25326402321083 0.0483945296013279 0.33528236194384 GO:0140693 molecular condensate scaffold activity 6/1034 48/18639 0.125 2.25326402321083 0.0483945296013279 0.33528236194384 GO:0045296 cadherin binding 26/1034 334/18639 0.0778443113772455 1.40323028990375 0.0516034813676439 0.355192793829237 GO:0001222 transcription corepressor binding 6/1034 49/18639 0.122448979591837 2.2072790431453 0.0526717854162579 0.35789802911047 GO:0035254 glutamate receptor binding 6/1034 49/18639 0.122448979591837 2.2072790431453 0.0526717854162579 0.35789802911047 GO:0035591 signaling adaptor activity 12/1034 129/18639 0.0930232558139535 1.67684764518015 0.054741570142229 0.369592766565368 GO:0030275 LRR domain binding 3/1034 16/18639 0.1875 3.37989603481625 0.0555072681846138 0.370048454564092 GO:0070411 I-SMAD binding 3/1034 16/18639 0.1875 3.37989603481625 0.0555072681846138 0.370048454564092 GO:0031406 carboxylic acid binding 16/1034 187/18639 0.0855614973262032 1.54234114957747 0.0566183447144696 0.375096533733361 GO:0033218 amide binding 20/1034 247/18639 0.0809716599190283 1.45960422556167 0.0582723516383617 0.383656476625238 GO:0141003 histone H2AX kinase activity 27/1034 354/18639 0.076271186440678 1.37487296331508 0.0588500814306 0.385068434052074 GO:0008266 poly(U) RNA binding 4/1034 27/18639 0.148148148148148 2.67053513862024 0.0598147846416407 0.386607754391093 GO:0008320 protein transmembrane transporter activity 4/1034 27/18639 0.148148148148148 2.67053513862024 0.0598147846416407 0.386607754391093 GO:1990782 protein tyrosine kinase binding 11/1034 117/18639 0.094017094017094 1.69476268412439 0.060199279301084 0.386734763994843 GO:0004842 ubiquitin-protein transferase activity 33/1034 449/18639 0.0734966592427617 1.32485902478321 0.0609706111898068 0.389330408802381 GO:0030544 Hsp70 protein binding 6/1034 51/18639 0.117647058823529 2.12071908066902 0.0618950802561486 0.392866976476153 GO:0140996 histone H3 kinase activity 27/1034 357/18639 0.0756302521008403 1.36331940900151 0.0638568683187096 0.401153834330266 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 3/1034 17/18639 0.176470588235294 3.18107862100353 0.0647144393117693 0.401153834330266 GO:0036041 long-chain fatty acid binding 3/1034 17/18639 0.176470588235294 3.18107862100353 0.0647144393117693 0.401153834330266 GO:0045125 bioactive lipid receptor activity 3/1034 17/18639 0.176470588235294 3.18107862100353 0.0647144393117693 0.401153834330266 GO:0036408 histone H3K14 acetyltransferase activity 4/1034 28/18639 0.142857142857143 2.57515888366952 0.0668474020820702 0.411831901941684 GO:0019209 kinase activator activity 13/1034 148/18639 0.0878378378378378 1.58337471901302 0.0679427358258628 0.411831901941684 GO:0030331 nuclear estrogen receptor binding 5/1034 40/18639 0.125 2.25326402321083 0.0687392996360416 0.411831901941684 GO:0061791 GTPase motor activity 5/1034 40/18639 0.125 2.25326402321083 0.0687392996360416 0.411831901941684 GO:1990606 membrane scission GTPase motor activity 5/1034 40/18639 0.125 2.25326402321083 0.0687392996360416 0.411831901941684 GO:0051087 protein-folding chaperone binding 12/1034 134/18639 0.0895522388059701 1.61427870319582 0.0689597331567538 0.411831901941684 GO:0035173 histone kinase activity 27/1034 360/18639 0.075 1.3519584139265 0.0691566778732261 0.411831901941684 GO:0000149 SNARE binding 10/1034 106/18639 0.0943396226415094 1.70057662129119 0.0696235352546026 0.412295795362451 GO:0016860 intramolecular oxidoreductase activity 6/1034 53/18639 0.113207547169811 2.04069194554943 0.0720130211620902 0.421733715092904 GO:0140296 general transcription initiation factor binding 6/1034 53/18639 0.113207547169811 2.04069194554943 0.0720130211620902 0.421733715092904 GO:0051213 dioxygenase activity 9/1034 93/18639 0.0967741935483871 1.74446246958258 0.0726874200508287 0.42334431458175 GO:0019888 protein phosphatase regulator activity 10/1034 107/18639 0.0934579439252336 1.68468338183987 0.0731833540200722 0.423903580662713 GO:0010484 histone H3 acetyltransferase activity 4/1034 29/18639 0.137931034482759 2.48636030147402 0.0742880178945795 0.426752863881937 GO:0004706 JUN kinase kinase kinase activity 3/1034 18/18639 0.166666666666667 3.00435203094778 0.0745715148284071 0.426752863881937 GO:0042287 MHC protein binding 5/1034 41/18639 0.121951219512195 2.19830636410813 0.0748830497000379 0.426752863881937 GO:0048306 calcium-dependent protein binding 8/1034 80/18639 0.1 1.80261121856867 0.0753144977080579 0.426916404120542 GO:0016410 N-acyltransferase activity 9/1034 94/18639 0.0957446808510638 1.72590435820404 0.0766373743243748 0.430967856236186 GO:0033192 calmodulin-dependent protein phosphatase activity 8/1034 81/18639 0.0987654320987654 1.78035675908016 0.079722438970429 0.430967856236186 GO:0140791 histone H2AXS140 phosphatase activity 8/1034 81/18639 0.0987654320987654 1.78035675908016 0.079722438970429 0.430967856236186 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 8/1034 81/18639 0.0987654320987654 1.78035675908016 0.079722438970429 0.430967856236186 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 8/1034 81/18639 0.0987654320987654 1.78035675908016 0.079722438970429 0.430967856236186 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 8/1034 81/18639 0.0987654320987654 1.78035675908016 0.079722438970429 0.430967856236186 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 8/1034 81/18639 0.0987654320987654 1.78035675908016 0.079722438970429 0.430967856236186 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 8/1034 81/18639 0.0987654320987654 1.78035675908016 0.079722438970429 0.430967856236186 GO:1990439 MAP kinase serine/threonine phosphatase activity 8/1034 81/18639 0.0987654320987654 1.78035675908016 0.079722438970429 0.430967856236186 GO:0016791 phosphatase activity 21/1034 273/18639 0.0769230769230769 1.38662401428359 0.0815764716038525 0.430967856236186 GO:0030145 manganese ion binding 7/1034 68/18639 0.102941176470588 1.85562919558539 0.0820704227478613 0.430967856236186 GO:0008187 poly-pyrimidine tract binding 4/1034 30/18639 0.133333333333333 2.40348162475822 0.082127836754443 0.430967856236186 GO:0043995 histone H4K5 acetyltransferase activity 4/1034 30/18639 0.133333333333333 2.40348162475822 0.082127836754443 0.430967856236186 GO:0043996 histone H4K8 acetyltransferase activity 4/1034 30/18639 0.133333333333333 2.40348162475822 0.082127836754443 0.430967856236186 GO:0043997 histone H4K12 acetyltransferase activity 4/1034 30/18639 0.133333333333333 2.40348162475822 0.082127836754443 0.430967856236186 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 8/1034 82/18639 0.0975609756097561 1.7586450912865 0.0842805971211815 0.437222667610117 GO:0033549 MAP kinase phosphatase activity 8/1034 82/18639 0.0975609756097561 1.7586450912865 0.0842805971211815 0.437222667610117 GO:0016407 acetyltransferase activity 9/1034 96/18639 0.09375 1.68994801740812 0.084923783735219 0.437222667610117 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 3/1034 19/18639 0.157894736842105 2.84622823984526 0.0850467418908564 0.437222667610117 GO:0030295 protein kinase activator activity 12/1034 139/18639 0.0863309352517986 1.55621112394417 0.0853821624483908 0.437222667610117 GO:0008080 N-acetyltransferase activity 7/1034 69/18639 0.101449275362319 1.82873601883778 0.0872029857706216 0.444399831331053 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 8/1034 83/18639 0.0963855421686747 1.73745659621076 0.0889886453217521 0.451329971488312 GO:0097110 scaffold protein binding 7/1034 70/18639 0.1 1.80261121856867 0.0925134781712948 0.465541192577565 GO:0043022 ribosome binding 10/1034 112/18639 0.0892857142857143 1.60947430229345 0.0926690487111945 0.465541192577565 GO:0042626 ATPase-coupled transmembrane transporter activity 9/1034 98/18639 0.0918367346938776 1.65545928235898 0.0937251645608916 0.467027216831601 GO:0017018 myosin phosphatase activity 8/1034 84/18639 0.0952380952380952 1.71677258911301 0.0938460350803122 0.467027216831601 GO:0019783 ubiquitin-like protein peptidase activity 11/1034 127/18639 0.0866141732283465 1.56131680348467 0.0949229741895627 0.468486539685051 GO:0003954 NADH dehydrogenase activity 5/1034 44/18639 0.113636363636364 2.04842183928257 0.0950232132380056 0.468486539685051 GO:0000339 RNA cap binding 3/1034 20/18639 0.15 2.703916827853 0.0961060917588888 0.469451084219103 GO:0070717 poly-purine tract binding 4/1034 32/18639 0.125 2.25326402321083 0.0989627349699707 0.469451084219103 GO:0120015 sterol transfer activity 4/1034 32/18639 0.125 2.25326402321083 0.0989627349699707 0.469451084219103 GO:0140303 intramembrane lipid transporter activity 5/1034 45/18639 0.111111111111111 2.00290135396518 0.102290844602534 0.469451084219103 GO:0005381 iron ion transmembrane transporter activity 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.469451084219103 GO:0008140 cAMP response element binding protein binding 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.469451084219103 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.469451084219103 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.469451084219103 GO:0031434 mitogen-activated protein kinase kinase binding 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.469451084219103 GO:0035256 G protein-coupled glutamate receptor binding 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.469451084219103 GO:0045322 unmethylated CpG binding 2/1034 10/18639 0.2 3.60522243713733 0.102937142635922 0.469451084219103 GO:0101005 deubiquitinase activity 10/1034 115/18639 0.0869565217391304 1.56748801614667 0.105709678702432 0.469451084219103 GO:0031267 small GTPase binding 21/1034 283/18639 0.0742049469964664 1.33762669929124 0.10761173575752 0.469451084219103 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/1034 21/18639 0.142857142857143 2.57515888366952 0.107713818959834 0.469451084219103 GO:0001846 opsonin binding 3/1034 21/18639 0.142857142857143 2.57515888366952 0.107713818959834 0.469451084219103 GO:0051010 microtubule plus-end binding 3/1034 21/18639 0.142857142857143 2.57515888366952 0.107713818959834 0.469451084219103 GO:0030296 protein tyrosine kinase activator activity 4/1034 33/18639 0.121212121212121 2.18498329523475 0.107933478694051 0.469451084219103 GO:0071889 14-3-3 protein binding 4/1034 33/18639 0.121212121212121 2.18498329523475 0.107933478694051 0.469451084219103 GO:0140311 protein sequestering activity 4/1034 33/18639 0.121212121212121 2.18498329523475 0.107933478694051 0.469451084219103 GO:0003924 GTPase activity 24/1034 331/18639 0.0725075528700906 1.30702928234586 0.10938956652587 0.469451084219103 GO:0043539 protein serine/threonine kinase activator activity 7/1034 73/18639 0.0958904109589041 1.7285313054768 0.109497864589148 0.469451084219103 GO:0004180 carboxypeptidase activity 5/1034 46/18639 0.108695652173913 1.95936002018333 0.109826080885557 0.469451084219103 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 6/1034 60/18639 0.1 1.80261121856867 0.114344087766515 0.469451084219103 GO:0016651 oxidoreductase activity, acting on NAD(P)H 8/1034 88/18639 0.0909090909090909 1.63873747142606 0.114750439485576 0.469451084219103 GO:0019208 phosphatase regulator activity 10/1034 117/18639 0.0854700854700855 1.54069334920399 0.11495998464519 0.469451084219103 GO:0048029 monosaccharide binding 7/1034 74/18639 0.0945945945945946 1.70517277432171 0.115503910024209 0.469451084219103 GO:0031625 ubiquitin protein ligase binding 22/1034 302/18639 0.0728476821192053 1.31316049034803 0.116897148566308 0.469451084219103 GO:0061733 protein-lysine-acetyltransferase activity 5/1034 47/18639 0.106382978723404 1.9176715091156 0.117622216327532 0.469451084219103 GO:0140359 ABC-type transporter activity 5/1034 47/18639 0.106382978723404 1.9176715091156 0.117622216327532 0.469451084219103 GO:0004722 protein serine/threonine phosphatase activity 9/1034 103/18639 0.087378640776699 1.57509718127359 0.117957644579315 0.469451084219103 GO:0004407 histone deacetylase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0032931 histone H3K56 acetyltransferase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0033558 protein lysine deacetylase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0043992 histone H3K9 acetyltransferase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0043993 histone H3K18 acetyltransferase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0043994 histone H3K23 acetyltransferase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0043999 histone H2AK5 acetyltransferase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0044012 histone H2AK9 acetyltransferase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0044014 histone H2BK5 acetyltransferase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0044015 histone H2BK12 acetyltransferase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0044016 histone H3K4 acetyltransferase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0044017 histone H3K27 acetyltransferase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0044018 histone H3K36 acetyltransferase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0046972 histone H4K16 acetyltransferase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0070034 telomerase RNA binding 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0140908 histone H3K122 acetyltransferase activity 3/1034 22/18639 0.136363636363636 2.45810620713909 0.119832953990289 0.469451084219103 GO:0015026 coreceptor activity 6/1034 61/18639 0.0983606557377049 1.77306021498557 0.121236035104609 0.469451084219103 GO:0005536 D-glucose binding 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.469451084219103 GO:0008432 JUN kinase binding 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.469451084219103 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.469451084219103 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.469451084219103 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.469451084219103 GO:0019107 myristoyltransferase activity 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.469451084219103 GO:0019864 IgG binding 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.469451084219103 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.469451084219103 GO:0034713 type I transforming growth factor beta receptor binding 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.469451084219103 GO:0043522 leucine zipper domain binding 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.469451084219103 GO:0070697 activin receptor binding 2/1034 11/18639 0.181818181818182 3.27747494285212 0.121348676486825 0.469451084219103 GO:0061630 ubiquitin protein ligase activity 25/1034 353/18639 0.0708215297450425 1.27663684034608 0.125880360158786 0.484710768554702 GO:0000175 3'-5'-RNA exonuclease activity 4/1034 35/18639 0.114285714285714 2.06012710693562 0.126912670036297 0.484710768554702 GO:0010485 histone H4 acetyltransferase activity 4/1034 35/18639 0.114285714285714 2.06012710693562 0.126912670036297 0.484710768554702 GO:0016853 isomerase activity 14/1034 180/18639 0.0777777777777778 1.40203094777563 0.12712225816812 0.484710768554702 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/1034 23/18639 0.130434782608696 2.35123202422 0.132425735830014 0.5006563359655 GO:0044013 histone H2B acetyltransferase activity 3/1034 23/18639 0.130434782608696 2.35123202422 0.132425735830014 0.5006563359655 GO:0015399 primary active transmembrane transporter activity 13/1034 166/18639 0.0783132530120482 1.41168348442124 0.132721160760666 0.5006563359655 GO:0140789 histone phosphatase activity 11/1034 136/18639 0.0808823529411765 1.45799436795995 0.134661880626195 0.503067961484379 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 17/1034 229/18639 0.074235807860262 1.33818300068416 0.136242640677983 0.503067961484379 GO:0005484 SNAP receptor activity 4/1034 36/18639 0.111111111111111 2.00290135396518 0.13689089755275 0.503067961484379 GO:0016409 palmitoyltransferase activity 4/1034 36/18639 0.111111111111111 2.00290135396518 0.13689089755275 0.503067961484379 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 10/1034 122/18639 0.0819672131147541 1.47755017915464 0.139987888550502 0.503067961484379 GO:0000340 RNA 7-methylguanosine cap binding 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.503067961484379 GO:0003720 telomerase activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.503067961484379 GO:0005078 MAP-kinase scaffold activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.503067961484379 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.503067961484379 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.503067961484379 GO:0035197 siRNA binding 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.503067961484379 GO:0035497 cAMP response element binding 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.503067961484379 GO:0070008 serine-type exopeptidase activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.503067961484379 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.503067961484379 GO:1990817 poly(A) RNA polymerase activity 2/1034 12/18639 0.166666666666667 3.00435203094778 0.14047935528243 0.503067961484379 GO:0042393 histone binding 18/1034 247/18639 0.0728744939271255 1.3136438030055 0.14446575405646 0.507175096771069 GO:0004843 cysteine-type deubiquitinase activity 9/1034 108/18639 0.0833333333333333 1.50217601547389 0.145274257795928 0.507175096771069 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 3/1034 24/18639 0.125 2.25326402321083 0.145453990017363 0.507175096771069 GO:0043998 histone H2A acetyltransferase activity 3/1034 24/18639 0.125 2.25326402321083 0.145453990017363 0.507175096771069 GO:0060229 lipase activator activity 3/1034 24/18639 0.125 2.25326402321083 0.145453990017363 0.507175096771069 GO:0070300 phosphatidic acid binding 3/1034 24/18639 0.125 2.25326402321083 0.145453990017363 0.507175096771069 GO:0070840 dynein complex binding 3/1034 24/18639 0.125 2.25326402321083 0.145453990017363 0.507175096771069 GO:0140033 acetylation-dependent protein binding 3/1034 24/18639 0.125 2.25326402321083 0.145453990017363 0.507175096771069 GO:0019213 deacetylase activity 4/1034 37/18639 0.108108108108108 1.9487688849391 0.147173543586183 0.511488380988044 GO:0033293 monocarboxylic acid binding 7/1034 79/18639 0.0886075949367089 1.59725044683299 0.148000837506613 0.51268263972879 GO:0038024 cargo receptor activity 6/1034 65/18639 0.0923076923076923 1.66394881714031 0.150754375555208 0.519440540836761 GO:0005048 signal sequence binding 5/1034 51/18639 0.0980392156862745 1.76726590055752 0.151261713996885 0.519440540836761 GO:0042277 peptide binding 18/1034 249/18639 0.072289156626506 1.30309244715807 0.151996075604457 0.519440540836761 GO:0042578 phosphoric ester hydrolase activity 25/1034 363/18639 0.068870523415978 1.24146778138338 0.155968371331035 0.519440540836761 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 4/1034 38/18639 0.105263157894737 1.89748549323017 0.157743890664108 0.519440540836761 GO:0140375 immune receptor activity 12/1034 156/18639 0.0769230769230769 1.38662401428359 0.157843401637013 0.519440540836761 GO:0000030 mannosyltransferase activity 3/1034 25/18639 0.12 2.1631334622824 0.158879457551191 0.519440540836761 GO:0005537 D-mannose binding 3/1034 25/18639 0.12 2.1631334622824 0.158879457551191 0.519440540836761 GO:0015645 fatty acid ligase activity 3/1034 25/18639 0.12 2.1631334622824 0.158879457551191 0.519440540836761 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 3/1034 25/18639 0.12 2.1631334622824 0.158879457551191 0.519440540836761 GO:0042974 nuclear retinoic acid receptor binding 3/1034 25/18639 0.12 2.1631334622824 0.158879457551191 0.519440540836761 GO:0120515 fatty acid-CoA ligase activity 3/1034 25/18639 0.12 2.1631334622824 0.158879457551191 0.519440540836761 GO:0003964 RNA-directed DNA polymerase activity 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.519440540836761 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.519440540836761 GO:0005035 death receptor activity 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.519440540836761 GO:0005172 vascular endothelial growth factor receptor binding 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.519440540836761 GO:0030955 potassium ion binding 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.519440540836761 GO:0032396 inhibitory MHC class I receptor activity 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.519440540836761 GO:0097157 pre-mRNA intronic binding 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.519440540836761 GO:0140410 monoatomic cation:bicarbonate symporter activity 2/1034 13/18639 0.153846153846154 2.77324802856718 0.160192926105352 0.519440540836761 GO:0030159 signaling receptor complex adaptor activity 5/1034 52/18639 0.0961538461538462 1.73328001785449 0.16024250646568 0.519440540836761 GO:0001618 virus receptor activity 7/1034 81/18639 0.0864197530864197 1.55781216419514 0.162088844970102 0.523823706305818 GO:0004857 enzyme inhibitor activity 28/1034 416/18639 0.0673076923076923 1.21329601249814 0.168114627333436 0.537044874801294 GO:0000217 DNA secondary structure binding 4/1034 39/18639 0.102564102564103 1.84883201904478 0.168584781865404 0.537044874801294 GO:0140272 exogenous protein binding 7/1034 82/18639 0.0853658536585366 1.53881445487569 0.169350948102668 0.537044874801294 GO:0016251 RNA polymerase II general transcription initiation factor activity 5/1034 53/18639 0.0943396226415094 1.70057662129119 0.16943307785147 0.537044874801294 GO:0034212 protein N-acetyltransferase activity 5/1034 53/18639 0.0943396226415094 1.70057662129119 0.16943307785147 0.537044874801294 GO:0016887 ATP hydrolysis activity 28/1034 417/18639 0.0671462829736211 1.21038642973436 0.171257517518907 0.537044874801294 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/1034 26/18639 0.115384615384615 2.07993602142538 0.172664079437435 0.537044874801294 GO:0008157 protein phosphatase 1 binding 3/1034 26/18639 0.115384615384615 2.07993602142538 0.172664079437435 0.537044874801294 GO:0019865 immunoglobulin binding 3/1034 26/18639 0.115384615384615 2.07993602142538 0.172664079437435 0.537044874801294 GO:0030247 polysaccharide binding 3/1034 26/18639 0.115384615384615 2.07993602142538 0.172664079437435 0.537044874801294 GO:0051139 metal cation:proton antiporter activity 3/1034 26/18639 0.115384615384615 2.07993602142538 0.172664079437435 0.537044874801294 GO:0070006 metalloaminopeptidase activity 3/1034 26/18639 0.115384615384615 2.07993602142538 0.172664079437435 0.537044874801294 GO:0004721 phosphoprotein phosphatase activity 13/1034 175/18639 0.0742857142857143 1.33908261950815 0.174735762310366 0.537044874801294 GO:0032934 sterol binding 6/1034 68/18639 0.0882352941176471 1.59053931050176 0.174791072451831 0.537044874801294 GO:0001540 amyloid-beta binding 7/1034 83/18639 0.0843373493975904 1.52027452168442 0.176752739148279 0.537044874801294 GO:0008135 translation factor activity, RNA binding 7/1034 83/18639 0.0843373493975904 1.52027452168442 0.176752739148279 0.537044874801294 GO:0017069 snRNA binding 5/1034 54/18639 0.0925925925925926 1.66908446163765 0.178823533775589 0.537044874801294 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 5/1034 54/18639 0.0925925925925926 1.66908446163765 0.178823533775589 0.537044874801294 GO:0004532 RNA exonuclease activity 4/1034 40/18639 0.1 1.80261121856867 0.179678724335333 0.537044874801294 GO:0015036 disulfide oxidoreductase activity 4/1034 40/18639 0.1 1.80261121856867 0.179678724335333 0.537044874801294 GO:0032451 demethylase activity 4/1034 40/18639 0.1 1.80261121856867 0.179678724335333 0.537044874801294 GO:0071949 FAD binding 4/1034 40/18639 0.1 1.80261121856867 0.179678724335333 0.537044874801294 GO:0140662 ATP-dependent protein folding chaperone 4/1034 40/18639 0.1 1.80261121856867 0.179678724335333 0.537044874801294 GO:0008195 phosphatidate phosphatase activity 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.537044874801294 GO:0019763 immunoglobulin receptor activity 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.537044874801294 GO:0061665 SUMO ligase activity 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.537044874801294 GO:1901474 azole transmembrane transporter activity 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.537044874801294 GO:1990825 sequence-specific mRNA binding 2/1034 14/18639 0.142857142857143 2.57515888366952 0.180366014555906 0.537044874801294 GO:0002039 p53 binding 6/1034 69/18639 0.0869565217391304 1.56748801614667 0.183132794992899 0.543755637794041 GO:0180051 translation factor activity 7/1034 84/18639 0.0833333333333333 1.50217601547389 0.184289712245367 0.545389685300618 GO:0051015 actin filament binding 15/1034 209/18639 0.0717703349282297 1.29374010902057 0.185563591907058 0.545389685300618 GO:0004683 calcium/calmodulin-dependent protein kinase activity 3/1034 27/18639 0.111111111111111 2.00290135396518 0.18677024128691 0.545389685300618 GO:0016405 CoA-ligase activity 3/1034 27/18639 0.111111111111111 2.00290135396518 0.18677024128691 0.545389685300618 GO:0035255 ionotropic glutamate receptor binding 3/1034 27/18639 0.111111111111111 2.00290135396518 0.18677024128691 0.545389685300618 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/1034 27/18639 0.111111111111111 2.00290135396518 0.18677024128691 0.545389685300618 GO:0140313 molecular sequestering activity 5/1034 55/18639 0.0909090909090909 1.63873747142606 0.188403708741428 0.545737104165908 GO:0061134 peptidase regulator activity 16/1034 226/18639 0.0707964601769911 1.27618493349994 0.18993401712655 0.545737104165908 GO:0008137 NADH dehydrogenase (ubiquinone) activity 4/1034 41/18639 0.0975609756097561 1.7586450912865 0.191007986458068 0.545737104165908 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/1034 41/18639 0.0975609756097561 1.7586450912865 0.191007986458068 0.545737104165908 GO:0016877 ligase activity, forming carbon-sulfur bonds 4/1034 41/18639 0.0975609756097561 1.7586450912865 0.191007986458068 0.545737104165908 GO:0017080 sodium channel regulator activity 4/1034 41/18639 0.0975609756097561 1.7586450912865 0.191007986458068 0.545737104165908 GO:0042169 SH2 domain binding 4/1034 41/18639 0.0975609756097561 1.7586450912865 0.191007986458068 0.545737104165908 GO:0140828 metal cation:monoatomic cation antiporter activity 4/1034 41/18639 0.0975609756097561 1.7586450912865 0.191007986458068 0.545737104165908 GO:0022804 active transmembrane transporter activity 30/1034 457/18639 0.0656455142231947 1.1833334038744 0.193101056677812 0.550234193759358 GO:0000774 adenyl-nucleotide exchange factor activity 2/1034 15/18639 0.133333333333333 2.40348162475822 0.200887117422394 0.557683038864816 GO:0005523 tropomyosin binding 2/1034 15/18639 0.133333333333333 2.40348162475822 0.200887117422394 0.557683038864816 GO:0016846 carbon-sulfur lyase activity 2/1034 15/18639 0.133333333333333 2.40348162475822 0.200887117422394 0.557683038864816 GO:0048531 beta-1,3-galactosyltransferase activity 2/1034 15/18639 0.133333333333333 2.40348162475822 0.200887117422394 0.557683038864816 GO:0141050 histone H3K deacetylase activity 2/1034 15/18639 0.133333333333333 2.40348162475822 0.200887117422394 0.557683038864816 GO:0141051 histone H4K deacetylase activity 2/1034 15/18639 0.133333333333333 2.40348162475822 0.200887117422394 0.557683038864816 GO:0046966 nuclear thyroid hormone receptor binding 3/1034 28/18639 0.107142857142857 1.93136916275214 0.20116098199149 0.557683038864816 GO:0097718 disordered domain specific binding 3/1034 28/18639 0.107142857142857 1.93136916275214 0.20116098199149 0.557683038864816 GO:0141052 histone H3 demethylase activity 3/1034 28/18639 0.107142857142857 1.93136916275214 0.20116098199149 0.557683038864816 GO:0004402 histone acetyltransferase activity 4/1034 42/18639 0.0952380952380952 1.71677258911301 0.202554688644296 0.557683038864816 GO:0035198 miRNA binding 4/1034 42/18639 0.0952380952380952 1.71677258911301 0.202554688644296 0.557683038864816 GO:0042056 chemoattractant activity 4/1034 42/18639 0.0952380952380952 1.71677258911301 0.202554688644296 0.557683038864816 GO:0043175 RNA polymerase core enzyme binding 4/1034 42/18639 0.0952380952380952 1.71677258911301 0.202554688644296 0.557683038864816 GO:0005525 GTP binding 25/1034 378/18639 0.0661375661375661 1.19220318688404 0.207961257923325 0.570455365635104 GO:0022853 active monoatomic ion transmembrane transporter activity 9/1034 118/18639 0.076271186440678 1.37487296331508 0.208270025000741 0.570455365635104 GO:0005518 collagen binding 6/1034 72/18639 0.0833333333333333 1.50217601547389 0.209053485953579 0.571125502862871 GO:0019842 vitamin binding 11/1034 150/18639 0.0733333333333333 1.32191489361702 0.211270464059673 0.575698436769289 GO:0005543 phospholipid binding 32/1034 497/18639 0.0643863179074447 1.16063498982288 0.214298586666286 0.578706914660877 GO:0008375 acetylglucosaminyltransferase activity 4/1034 43/18639 0.0930232558139535 1.67684764518015 0.214300887751169 0.578706914660877 GO:0048156 tau protein binding 4/1034 43/18639 0.0930232558139535 1.67684764518015 0.214300887751169 0.578706914660877 GO:0035250 UDP-galactosyltransferase activity 3/1034 29/18639 0.103448275862069 1.86477022610552 0.215800170156518 0.578706914660877 GO:0106222 lncRNA binding 3/1034 29/18639 0.103448275862069 1.86477022610552 0.215800170156518 0.578706914660877 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 5/1034 58/18639 0.0862068965517241 1.55397518842126 0.218177721707278 0.578706914660877 GO:0061980 regulatory RNA binding 5/1034 58/18639 0.0862068965517241 1.55397518842126 0.218177721707278 0.578706914660877 GO:0051020 GTPase binding 21/1034 315/18639 0.0666666666666667 1.20174081237911 0.221546789322337 0.578706914660877 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.578706914660877 GO:0004708 MAP kinase kinase activity 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.578706914660877 GO:0005159 insulin-like growth factor receptor binding 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.578706914660877 GO:0015385 sodium:proton antiporter activity 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.578706914660877 GO:0022858 alanine transmembrane transporter activity 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.578706914660877 GO:0034450 ubiquitin-ubiquitin ligase activity 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.578706914660877 GO:0043023 ribosomal large subunit binding 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.578706914660877 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.578706914660877 GO:0140328 floppase activity 2/1034 16/18639 0.125 2.25326402321083 0.221655667313506 0.578706914660877 GO:0030547 signaling receptor inhibitor activity 4/1034 44/18639 0.0909090909090909 1.63873747142606 0.226228655202486 0.589195023377482 GO:0001965 G-protein alpha-subunit binding 3/1034 30/18639 0.1 1.80261121856867 0.230652651645638 0.591989856523913 GO:0001968 fibronectin binding 3/1034 30/18639 0.1 1.80261121856867 0.230652651645638 0.591989856523913 GO:0015215 nucleotide transmembrane transporter activity 3/1034 30/18639 0.1 1.80261121856867 0.230652651645638 0.591989856523913 GO:0031210 phosphatidylcholine binding 3/1034 30/18639 0.1 1.80261121856867 0.230652651645638 0.591989856523913 GO:0032452 histone demethylase activity 3/1034 30/18639 0.1 1.80261121856867 0.230652651645638 0.591989856523913 GO:0033612 receptor serine/threonine kinase binding 3/1034 30/18639 0.1 1.80261121856867 0.230652651645638 0.591989856523913 GO:0046982 protein heterodimerization activity 24/1034 369/18639 0.0650406504065041 1.17243006085767 0.237923286399298 0.608721344228259 GO:0042605 peptide antigen binding 4/1034 45/18639 0.0888888888888889 1.60232108317215 0.238320148919554 0.608721344228259 GO:0008234 cysteine-type peptidase activity 13/1034 187/18639 0.0695187165775401 1.25315218403169 0.239469696864976 0.610187208357871 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.610767995419836 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.610767995419836 GO:0045236 CXCR chemokine receptor binding 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.610767995419836 GO:0046965 nuclear retinoid X receptor binding 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.610767995419836 GO:0048038 quinone binding 2/1034 17/18639 0.117647058823529 2.12071908066902 0.242581164380404 0.610767995419836 GO:0140767 enzyme-substrate adaptor activity 10/1034 139/18639 0.0719424460431655 1.29684260328681 0.243154805723746 0.610767995419836 GO:0016878 acid-thiol ligase activity 3/1034 31/18639 0.0967741935483871 1.74446246958258 0.245684371298325 0.612765726061706 GO:0072349 modified amino acid transmembrane transporter activity 3/1034 31/18639 0.0967741935483871 1.74446246958258 0.245684371298325 0.612765726061706 GO:0140457 protein demethylase activity 3/1034 31/18639 0.0967741935483871 1.74446246958258 0.245684371298325 0.612765726061706 GO:0030291 protein serine/threonine kinase inhibitor activity 4/1034 46/18639 0.0869565217391304 1.56748801614667 0.250557679208506 0.62345338019018 GO:0140030 modification-dependent protein binding 12/1034 173/18639 0.069364161849711 1.25036616316902 0.253283468702876 0.627859129907568 GO:0003724 RNA helicase activity 6/1034 77/18639 0.0779220779220779 1.40463211836519 0.254812659989099 0.627859129907568 GO:0008378 galactosyltransferase activity 3/1034 32/18639 0.09375 1.68994801740812 0.260862471608155 0.627859129907568 GO:0030515 snoRNA binding 3/1034 32/18639 0.09375 1.68994801740812 0.260862471608155 0.627859129907568 GO:0051059 NF-kappaB binding 3/1034 32/18639 0.09375 1.68994801740812 0.260862471608155 0.627859129907568 GO:0001784 phosphotyrosine residue binding 4/1034 47/18639 0.0851063829787234 1.53413720729248 0.26292376877883 0.627859129907568 GO:0043495 protein-membrane adaptor activity 4/1034 47/18639 0.0851063829787234 1.53413720729248 0.26292376877883 0.627859129907568 GO:0140938 histone H3 methyltransferase activity 4/1034 47/18639 0.0851063829787234 1.53413720729248 0.26292376877883 0.627859129907568 GO:0000400 four-way junction DNA binding 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.627859129907568 GO:0008525 phosphatidylcholine transporter activity 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.627859129907568 GO:0016854 racemase and epimerase activity 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.627859129907568 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.627859129907568 GO:0017128 phospholipid scramblase activity 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.627859129907568 GO:0031690 adrenergic receptor binding 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.627859129907568 GO:0032393 MHC class I receptor activity 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.627859129907568 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.627859129907568 GO:0070628 proteasome binding 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.627859129907568 GO:1901611 phosphatidylglycerol binding 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.627859129907568 GO:1990381 ubiquitin-specific protease binding 2/1034 18/18639 0.111111111111111 2.00290135396518 0.263582370574403 0.627859129907568 GO:0005126 cytokine receptor binding 18/1034 275/18639 0.0654545454545455 1.17989097942676 0.267528747728329 0.63583065603594 GO:0005507 copper ion binding 5/1034 63/18639 0.0793650793650794 1.43064382426085 0.270598434904097 0.641687563754682 GO:0008186 ATP-dependent activity, acting on RNA 6/1034 79/18639 0.0759493670886076 1.36907181157114 0.273839135926583 0.647922955540575 GO:0019956 chemokine binding 3/1034 33/18639 0.0909090909090909 1.63873747142606 0.276155370899566 0.651948091655991 GO:0005178 integrin binding 11/1034 161/18639 0.0683229813664596 1.23159772697238 0.281661337718579 0.660091369617695 GO:0003756 protein disulfide isomerase activity 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.660091369617695 GO:0005520 insulin-like growth factor binding 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.660091369617695 GO:0008301 DNA binding, bending 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.660091369617695 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.660091369617695 GO:0022821 solute:potassium antiporter activity 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.660091369617695 GO:0031420 alkali metal ion binding 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.660091369617695 GO:0042577 lipid phosphatase activity 2/1034 19/18639 0.105263157894737 1.89748549323017 0.284586562184233 0.660091369617695 GO:0060590 ATPase regulator activity 4/1034 49/18639 0.0816326530612245 1.47151936209687 0.287973099251509 0.664869100271302 GO:0015035 protein-disulfide reductase activity 3/1034 34/18639 0.0882352941176471 1.59053931050176 0.291532823310921 0.664869100271302 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 3/1034 34/18639 0.0882352941176471 1.59053931050176 0.291532823310921 0.664869100271302 GO:0016831 carboxy-lyase activity 3/1034 34/18639 0.0882352941176471 1.59053931050176 0.291532823310921 0.664869100271302 GO:0030332 cyclin binding 3/1034 34/18639 0.0882352941176471 1.59053931050176 0.291532823310921 0.664869100271302 GO:0052866 phosphatidylinositol phosphate phosphatase activity 3/1034 34/18639 0.0882352941176471 1.59053931050176 0.291532823310921 0.664869100271302 GO:0015293 symporter activity 10/1034 146/18639 0.0684931506849315 1.23466521819772 0.29198620331896 0.664869100271302 GO:0120013 lipid transfer activity 5/1034 65/18639 0.0769230769230769 1.38662401428359 0.292291510119271 0.664869100271302 GO:0160215 deacylase activity 5/1034 65/18639 0.0769230769230769 1.38662401428359 0.292291510119271 0.664869100271302 GO:0016798 hydrolase activity, acting on glycosyl bonds 9/1034 130/18639 0.0692307692307692 1.24796161285523 0.295406315875782 0.670515406484645 GO:0019001 guanyl nucleotide binding 25/1034 400/18639 0.0625 1.12663201160542 0.296973218745077 0.671197466673309 GO:0032561 guanyl ribonucleotide binding 25/1034 400/18639 0.0625 1.12663201160542 0.296973218745077 0.671197466673309 GO:0015085 calcium ion transmembrane transporter activity 10/1034 147/18639 0.0680272108843537 1.22626613508072 0.299176176937901 0.67391429591339 GO:0016758 hexosyltransferase activity 13/1034 197/18639 0.065989847715736 1.18954039804024 0.299446823938874 0.67391429591339 GO:0004725 protein tyrosine phosphatase activity 7/1034 98/18639 0.0714285714285714 1.28757944183476 0.301171768247687 0.676360326996924 GO:0140713 histone chaperone activity 11/1034 164/18639 0.0670731707317073 1.20906850025947 0.302000995974116 0.676788701337343 GO:0008235 metalloexopeptidase activity 5/1034 66/18639 0.0757575757575758 1.36561455952172 0.303250196534118 0.677532566687225 GO:0001972 retinoic acid binding 2/1034 20/18639 0.1 1.80261121856867 0.305528836675937 0.677532566687225 GO:0016004 phospholipase activator activity 2/1034 20/18639 0.1 1.80261121856867 0.305528836675937 0.677532566687225 GO:0043024 ribosomal small subunit binding 2/1034 20/18639 0.1 1.80261121856867 0.305528836675937 0.677532566687225 GO:0061608 nuclear import signal receptor activity 2/1034 20/18639 0.1 1.80261121856867 0.305528836675937 0.677532566687225 GO:0034061 DNA polymerase activity 3/1034 35/18639 0.0857142857142857 1.54509533020171 0.306965962680416 0.679298372528688 GO:0016830 carbon-carbon lyase activity 4/1034 51/18639 0.0784313725490196 1.41381272044601 0.313334500802669 0.691947022605894 GO:0000993 RNA polymerase II complex binding 3/1034 36/18639 0.0833333333333333 1.50217601547389 0.322427332237477 0.703114955949029 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 3/1034 36/18639 0.0833333333333333 1.50217601547389 0.322427332237477 0.703114955949029 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 3/1034 36/18639 0.0833333333333333 1.50217601547389 0.322427332237477 0.703114955949029 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 3/1034 36/18639 0.0833333333333333 1.50217601547389 0.322427332237477 0.703114955949029 GO:0051117 ATPase binding 6/1034 84/18639 0.0714285714285714 1.28757944183476 0.322684871048164 0.703114955949029 GO:0003777 microtubule motor activity 5/1034 68/18639 0.0735294117647059 1.32544942541814 0.325339303073956 0.703114955949029 GO:0005548 phospholipid transporter activity 5/1034 68/18639 0.0735294117647059 1.32544942541814 0.325339303073956 0.703114955949029 GO:0140223 general transcription initiation factor activity 5/1034 68/18639 0.0735294117647059 1.32544942541814 0.325339303073956 0.703114955949029 GO:1990841 promoter-specific chromatin binding 5/1034 68/18639 0.0735294117647059 1.32544942541814 0.325339303073956 0.703114955949029 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/1034 21/18639 0.0952380952380952 1.71677258911301 0.326351470119738 0.703114955949029 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/1034 21/18639 0.0952380952380952 1.71677258911301 0.326351470119738 0.703114955949029 GO:0140312 cargo adaptor activity 2/1034 21/18639 0.0952380952380952 1.71677258911301 0.326351470119738 0.703114955949029 GO:0015297 antiporter activity 9/1034 135/18639 0.0666666666666667 1.20174081237911 0.334181726295998 0.718524604206406 GO:0008238 exopeptidase activity 7/1034 102/18639 0.0686274509803922 1.23708613039026 0.337223807775986 0.723564355421855 GO:0023023 MHC protein complex binding 3/1034 37/18639 0.0810810810810811 1.46157666370432 0.337890901824357 0.723564355421855 GO:0050660 flavin adenine dinucleotide binding 6/1034 86/18639 0.0697674418604651 1.25763573388512 0.342578292855781 0.731876157856661 GO:0003774 cytoskeletal motor activity 10/1034 153/18639 0.065359477124183 1.17817726703834 0.343153255146001 0.731876157856661 GO:0008970 phospholipase A1 activity 2/1034 22/18639 0.0909090909090909 1.63873747142606 0.347003321732683 0.73417868470388 GO:0015377 chloride:monoatomic cation symporter activity 2/1034 22/18639 0.0909090909090909 1.63873747142606 0.347003321732683 0.73417868470388 GO:0050321 tau-protein kinase activity 2/1034 22/18639 0.0909090909090909 1.63873747142606 0.347003321732683 0.73417868470388 GO:0061133 endopeptidase activator activity 2/1034 22/18639 0.0909090909090909 1.63873747142606 0.347003321732683 0.73417868470388 GO:0005506 iron ion binding 10/1034 154/18639 0.0649350649350649 1.17052676530433 0.350594645759907 0.738190789235254 GO:0015485 cholesterol binding 4/1034 54/18639 0.0740740740740741 1.33526756931012 0.351685234494154 0.738190789235254 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 4/1034 54/18639 0.0740740740740741 1.33526756931012 0.351685234494154 0.738190789235254 GO:0140463 chromatin-protein adaptor activity 4/1034 54/18639 0.0740740740740741 1.33526756931012 0.351685234494154 0.738190789235254 GO:0042887 amide transmembrane transporter activity 3/1034 38/18639 0.0789473684210526 1.42311411992263 0.353332074209521 0.738721890852252 GO:0043531 ADP binding 3/1034 38/18639 0.0789473684210526 1.42311411992263 0.353332074209521 0.738721890852252 GO:0003697 single-stranded DNA binding 8/1034 121/18639 0.0661157024793388 1.19180907012804 0.357086177250803 0.743637225708941 GO:0004540 RNA nuclease activity 8/1034 121/18639 0.0661157024793388 1.19180907012804 0.357086177250803 0.743637225708941 GO:0004197 cysteine-type endopeptidase activity 6/1034 88/18639 0.0681818181818182 1.22905310356954 0.362587385842802 0.751902778441181 GO:0098632 cell-cell adhesion mediator activity 4/1034 55/18639 0.0727272727272727 1.31098997714085 0.364491628670839 0.751902778441181 GO:0004602 glutathione peroxidase activity 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.751902778441181 GO:0005158 insulin receptor binding 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.751902778441181 GO:0005283 amino acid:sodium symporter activity 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.751902778441181 GO:0017134 fibroblast growth factor binding 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.751902778441181 GO:0042171 lysophosphatidic acid acyltransferase activity 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.751902778441181 GO:0070577 lysine-acetylated histone binding 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.751902778441181 GO:0071617 lysophospholipid acyltransferase activity 2/1034 23/18639 0.0869565217391304 1.56748801614667 0.367439282294841 0.751902778441181 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 3/1034 39/18639 0.0769230769230769 1.38662401428359 0.368727681904864 0.75308543895791 GO:0042379 chemokine receptor binding 5/1034 72/18639 0.0694444444444444 1.25181334622824 0.369921091529785 0.754069917349178 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 6/1034 89/18639 0.0674157303370786 1.21524351813618 0.372617752713865 0.756656739227388 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 6/1034 89/18639 0.0674157303370786 1.21524351813618 0.372617752713865 0.756656739227388 GO:0140793 histone H2AXY142 phosphatase activity 6/1034 90/18639 0.0666666666666667 1.20174081237911 0.382656217519419 0.773779565377842 GO:0004177 aminopeptidase activity 3/1034 40/18639 0.075 1.3519584139265 0.384055975761852 0.773779565377842 GO:0050997 quaternary ammonium group binding 3/1034 40/18639 0.075 1.3519584139265 0.384055975761852 0.773779565377842 GO:0004622 lysophospholipase activity 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.773779565377842 GO:0004806 triacylglycerol lipase activity 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.773779565377842 GO:0015295 solute:proton symporter activity 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.773779565377842 GO:0048027 mRNA 5'-UTR binding 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.773779565377842 GO:0050431 transforming growth factor beta binding 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.773779565377842 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/1034 24/18639 0.0833333333333333 1.50217601547389 0.387619763410976 0.773779565377842 GO:0005496 steroid binding 7/1034 108/18639 0.0648148148148148 1.16835912314636 0.392185822545357 0.775997476464059 GO:0003684 damaged DNA binding 5/1034 74/18639 0.0675675675675676 1.21798055308694 0.392259560281882 0.775997476464059 GO:0005319 lipid transporter activity 11/1034 178/18639 0.0617977528089888 1.11397322495816 0.40067002456205 0.775997476464059 GO:0008408 3'-5' exonuclease activity 4/1034 58/18639 0.0689655172413793 1.24318015073701 0.402787220896954 0.775997476464059 GO:0001848 complement binding 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.775997476464059 GO:0008483 transaminase activity 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.775997476464059 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.775997476464059 GO:0017056 structural constituent of nuclear pore 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.775997476464059 GO:0019706 protein-cysteine S-palmitoyltransferase activity 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.775997476464059 GO:0019707 protein-cysteine S-acyltransferase activity 2/1034 25/18639 0.08 1.44208897485493 0.407510224790088 0.775997476464059 GO:0035091 phosphatidylinositol binding 17/1034 284/18639 0.0598591549295775 1.07902784210096 0.408769349553788 0.775997476464059 GO:0016859 cis-trans isomerase activity 3/1034 42/18639 0.0714285714285714 1.28757944183476 0.414430600177289 0.775997476464059 GO:0098631 cell adhesion mediator activity 5/1034 76/18639 0.0657894736842105 1.18592843326886 0.414533489276998 0.775997476464059 GO:0031593 polyubiquitin modification-dependent protein binding 4/1034 59/18639 0.0677966101694915 1.22210930072452 0.415469115188887 0.775997476464059 GO:0036002 pre-mRNA binding 4/1034 59/18639 0.0677966101694915 1.22210930072452 0.415469115188887 0.775997476464059 GO:0045309 protein phosphorylated amino acid binding 4/1034 59/18639 0.0677966101694915 1.22210930072452 0.415469115188887 0.775997476464059 GO:0070888 E-box binding 4/1034 59/18639 0.0677966101694915 1.22210930072452 0.415469115188887 0.775997476464059 GO:0015291 secondary active transmembrane transporter activity 17/1034 287/18639 0.0592334494773519 1.06774880542395 0.425873027486671 0.775997476464059 GO:0005160 transforming growth factor beta receptor binding 2/1034 26/18639 0.0769230769230769 1.38662401428359 0.427080736902809 0.775997476464059 GO:0008198 ferrous iron binding 2/1034 26/18639 0.0769230769230769 1.38662401428359 0.427080736902809 0.775997476464059 GO:0050681 nuclear androgen receptor binding 2/1034 26/18639 0.0769230769230769 1.38662401428359 0.427080736902809 0.775997476464059 GO:0070412 R-SMAD binding 2/1034 26/18639 0.0769230769230769 1.38662401428359 0.427080736902809 0.775997476464059 GO:0001098 basal transcription machinery binding 4/1034 60/18639 0.0666666666666667 1.20174081237911 0.428089701307392 0.775997476464059 GO:0001099 basal RNA polymerase II transcription machinery binding 4/1034 60/18639 0.0666666666666667 1.20174081237911 0.428089701307392 0.775997476464059 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 4/1034 60/18639 0.0666666666666667 1.20174081237911 0.428089701307392 0.775997476464059 GO:0004712 protein serine/threonine/tyrosine kinase activity 3/1034 43/18639 0.0697674418604651 1.25763573388512 0.429440328609249 0.775997476464059 GO:0016298 lipase activity 8/1034 130/18639 0.0615384615384615 1.10929921142687 0.433760333276528 0.775997476464059 GO:0001094 TFIID-class transcription factor complex binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0005131 growth hormone receptor binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0005345 purine nucleobase transmembrane transporter activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0015203 polyamine transmembrane transporter activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0031419 cobalamin binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0032052 bile acid binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0032395 MHC class II receptor activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0033204 ribonuclease P RNA binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0035374 chondroitin sulfate binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0042975 peroxisome proliferator activated receptor binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0043208 glycosphingolipid binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0043295 glutathione binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0043422 protein kinase B binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0140940 histone H2A methyltransferase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0140999 histone H3K4 trimethyltransferase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0141109 transporter activator activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:1905394 retromer complex binding 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:1990259 histone H2AQ104 methyltransferase activity 1/1034 10/18639 0.1 1.80261121856867 0.434968569652838 0.775997476464059 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 4/1034 61/18639 0.0655737704918033 1.18204014332372 0.44063803209363 0.775997476464059 GO:0019905 syntaxin binding 4/1034 61/18639 0.0655737704918033 1.18204014332372 0.44063803209363 0.775997476464059 GO:0004896 cytokine receptor activity 6/1034 96/18639 0.0625 1.12663201160542 0.442694508276929 0.775997476464059 GO:0008237 metallopeptidase activity 11/1034 184/18639 0.0597826086956522 1.07764801110083 0.443703957713033 0.775997476464059 GO:0001046 core promoter sequence-specific DNA binding 3/1034 44/18639 0.0681818181818182 1.22905310356954 0.44430947544389 0.775997476464059 GO:0019205 nucleobase-containing compound kinase activity 3/1034 44/18639 0.0681818181818182 1.22905310356954 0.44430947544389 0.775997476464059 GO:0001671 ATPase activator activity 2/1034 27/18639 0.0740740740740741 1.33526756931012 0.446305576552081 0.775997476464059 GO:0004364 glutathione transferase activity 2/1034 27/18639 0.0740740740740741 1.33526756931012 0.446305576552081 0.775997476464059 GO:0005385 zinc ion transmembrane transporter activity 2/1034 27/18639 0.0740740740740741 1.33526756931012 0.446305576552081 0.775997476464059 GO:0023026 MHC class II protein complex binding 2/1034 27/18639 0.0740740740740741 1.33526756931012 0.446305576552081 0.775997476464059 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/1034 27/18639 0.0740740740740741 1.33526756931012 0.446305576552081 0.775997476464059 GO:1901981 phosphatidylinositol phosphate binding 11/1034 185/18639 0.0594594594594595 1.0718228867165 0.450860919757009 0.775997476464059 GO:0015179 L-amino acid transmembrane transporter activity 4/1034 62/18639 0.0645161290322581 1.16297497972172 0.45310372624694 0.775997476464059 GO:0016247 channel regulator activity 10/1034 168/18639 0.0595238095238095 1.07298286819563 0.455989994387794 0.775997476464059 GO:0000049 tRNA binding 5/1034 80/18639 0.0625 1.12663201160542 0.458625400250748 0.775997476464059 GO:0004715 non-membrane spanning protein tyrosine kinase activity 3/1034 45/18639 0.0666666666666667 1.20174081237911 0.459022998767057 0.775997476464059 GO:0008009 chemokine activity 3/1034 45/18639 0.0666666666666667 1.20174081237911 0.459022998767057 0.775997476464059 GO:0000510 H3-H4 histone complex chaperone activity 9/1034 151/18639 0.0596026490066225 1.07440403755748 0.461547146652854 0.775997476464059 GO:0140584 chromatin extrusion motor activity 9/1034 151/18639 0.0596026490066225 1.07440403755748 0.461547146652854 0.775997476464059 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 9/1034 151/18639 0.0596026490066225 1.07440403755748 0.461547146652854 0.775997476464059 GO:0140849 ATP-dependent H2AZ histone chaperone activity 9/1034 151/18639 0.0596026490066225 1.07440403755748 0.461547146652854 0.775997476464059 GO:0046625 sphingolipid binding 2/1034 28/18639 0.0714285714285714 1.28757944183476 0.465162853056741 0.775997476464059 GO:0046875 ephrin receptor binding 2/1034 28/18639 0.0714285714285714 1.28757944183476 0.465162853056741 0.775997476464059 GO:0051393 alpha-actinin binding 2/1034 28/18639 0.0714285714285714 1.28757944183476 0.465162853056741 0.775997476464059 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/1034 28/18639 0.0714285714285714 1.28757944183476 0.465162853056741 0.775997476464059 GO:0009055 electron transfer activity 7/1034 116/18639 0.0603448275862069 1.08778263189488 0.465377068991451 0.775997476464059 GO:0015294 solute:monoatomic cation symporter activity 7/1034 116/18639 0.0603448275862069 1.08778263189488 0.465377068991451 0.775997476464059 GO:1901682 sulfur compound transmembrane transporter activity 4/1034 63/18639 0.0634920634920635 1.14451505940868 0.46547696633798 0.775997476464059 GO:0000099 sulfur amino acid transmembrane transporter activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0001851 complement component C3b binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0002162 dystroglycan binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0003953 NAD+ nucleosidase activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0005225 volume-sensitive anion channel activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0008526 phosphatidylinositol transfer activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0015205 nucleobase transmembrane transporter activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0019206 nucleoside kinase activity 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0031731 CCR6 chemokine receptor binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0032050 clathrin heavy chain binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0032794 GTPase activating protein binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0034511 U3 snoRNA binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0045294 alpha-catenin binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0140031 phosphorylation-dependent protein binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:1900750 oligopeptide binding 1/1034 11/18639 0.0909090909090909 1.63873747142606 0.466330558969439 0.775997476464059 GO:0015616 DNA translocase activity 9/1034 152/18639 0.0592105263157895 1.06733558994197 0.469465148989251 0.777624990643917 GO:0140674 ATP-dependent histone chaperone activity 9/1034 152/18639 0.0592105263157895 1.06733558994197 0.469465148989251 0.777624990643917 GO:0030971 receptor tyrosine kinase binding 5/1034 81/18639 0.0617283950617284 1.1127229744251 0.469509428313309 0.777624990643917 GO:0141108 transporter regulator activity 10/1034 170/18639 0.0588235294117647 1.06035954033451 0.470980043506409 0.778843753692346 GO:0140597 protein carrier chaperone 11/1034 188/18639 0.0585106382978723 1.05471933001358 0.472260350228537 0.7797445034926 GO:0030276 clathrin binding 3/1034 46/18639 0.0652173913043478 1.17561601211 0.473567090829281 0.779986052534649 GO:0061775 cohesin loader activity 9/1034 153/18639 0.0588235294117647 1.06035954033451 0.477359642354455 0.779986052534649 GO:0005416 amino acid:monoatomic cation symporter activity 2/1034 29/18639 0.0689655172413793 1.24318015073701 0.483634162901202 0.779986052534649 GO:0016417 S-acyltransferase activity 2/1034 29/18639 0.0689655172413793 1.24318015073701 0.483634162901202 0.779986052534649 GO:0043236 laminin binding 2/1034 29/18639 0.0689655172413793 1.24318015073701 0.483634162901202 0.779986052534649 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/1034 29/18639 0.0689655172413793 1.24318015073701 0.483634162901202 0.779986052534649 GO:0005504 fatty acid binding 3/1034 47/18639 0.0638297872340425 1.15060290546936 0.48792913551454 0.779986052534649 GO:0004386 helicase activity 9/1034 155/18639 0.0580645161290323 1.04667748174955 0.493066919993995 0.779986052534649 GO:0003995 acyl-CoA dehydrogenase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0004000 adenosine deaminase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0004526 ribonuclease P activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0004859 phospholipase inhibitor activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0004875 complement receptor activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0015166 polyol transmembrane transporter activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0015368 calcium:monoatomic cation antiporter activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0016273 arginine N-methyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0016274 protein-arginine N-methyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0016801 hydrolase activity, acting on ether bonds 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0016803 ether hydrolase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0017166 vinculin binding 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0031543 peptidyl-proline dioxygenase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0034452 dynactin binding 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0036009 protein-glutamine N-methyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0042301 phosphate ion binding 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0070410 co-SMAD binding 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:1990459 transferrin receptor binding 1/1034 12/18639 0.0833333333333333 1.50217601547389 0.495953395668258 0.779986052534649 GO:0015171 amino acid transmembrane transporter activity 6/1034 102/18639 0.0588235294117647 1.06035954033451 0.501483592318102 0.782210480121705 GO:0016769 transferase activity, transferring nitrogenous groups 2/1034 30/18639 0.0666666666666667 1.20174081237911 0.501704270848028 0.782210480121705 GO:0048019 receptor antagonist activity 2/1034 30/18639 0.0666666666666667 1.20174081237911 0.501704270848028 0.782210480121705 GO:0051721 protein phosphatase 2A binding 2/1034 30/18639 0.0666666666666667 1.20174081237911 0.501704270848028 0.782210480121705 GO:0098918 structural constituent of synapse 2/1034 30/18639 0.0666666666666667 1.20174081237911 0.501704270848028 0.782210480121705 GO:0032266 phosphatidylinositol-3-phosphate binding 3/1034 48/18639 0.0625 1.12663201160542 0.502097664076093 0.782210480121705 GO:0003735 structural constituent of ribosome 10/1034 175/18639 0.0571428571428571 1.03006355346781 0.50806770822649 0.782210480121705 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/1034 67/18639 0.0597014925373134 1.07618580213055 0.513868505070908 0.782210480121705 GO:0042054 histone methyltransferase activity 4/1034 67/18639 0.0597014925373134 1.07618580213055 0.513868505070908 0.782210480121705 GO:0050840 extracellular matrix binding 4/1034 67/18639 0.0597014925373134 1.07618580213055 0.513868505070908 0.782210480121705 GO:0140658 ATP-dependent chromatin remodeler activity 9/1034 158/18639 0.0569620253164557 1.02680385867835 0.51638341072883 0.782210480121705 GO:0004713 protein tyrosine kinase activity 8/1034 140/18639 0.0571428571428571 1.03006355346781 0.517535466168492 0.782210480121705 GO:0140104 molecular carrier activity 14/1034 249/18639 0.0562248995983936 1.01351634778961 0.518698045105503 0.782210480121705 GO:0008327 methyl-CpG binding 2/1034 31/18639 0.0645161290322581 1.16297497972172 0.51936081564456 0.782210480121705 GO:0016411 acylglycerol O-acyltransferase activity 2/1034 31/18639 0.0645161290322581 1.16297497972172 0.51936081564456 0.782210480121705 GO:0070273 phosphatidylinositol-4-phosphate binding 2/1034 31/18639 0.0645161290322581 1.16297497972172 0.51936081564456 0.782210480121705 GO:0016209 antioxidant activity 5/1034 86/18639 0.0581395348837209 1.0480297782376 0.522764674189108 0.782210480121705 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0004465 lipoprotein lipase activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0004535 poly(A)-specific ribonuclease activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0005542 folic acid binding 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0008035 high-density lipoprotein particle binding 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0008253 5'-nucleotidase activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0008417 fucosyltransferase activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0017154 semaphorin receptor activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0019104 DNA N-glycosylase activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0031994 insulin-like growth factor I binding 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0035673 oligopeptide transmembrane transporter activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0043560 insulin receptor substrate binding 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0046974 histone H3K9 methyltransferase activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0046975 histone H3K36 methyltransferase activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0071714 icosanoid transmembrane transporter activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0140333 glycerophospholipid flippase activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0140666 annealing activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/1034 13/18639 0.0769230769230769 1.38662401428359 0.523933434798501 0.782210480121705 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 4/1034 68/18639 0.0588235294117647 1.06035954033451 0.525651580195718 0.783671835453531 GO:0015605 organophosphate ester transmembrane transporter activity 3/1034 50/18639 0.06 1.0815667311412 0.529813760667331 0.787661411370787 GO:0048020 CCR chemokine receptor binding 3/1034 50/18639 0.06 1.0815667311412 0.529813760667331 0.787661411370787 GO:0003689 DNA clamp loader activity 9/1034 160/18639 0.05625 1.01396881044487 0.531735197869318 0.789410797957251 GO:0015106 bicarbonate transmembrane transporter activity 2/1034 32/18639 0.0625 1.12663201160542 0.53659403858032 0.79264048881485 GO:0031369 translation initiation factor binding 2/1034 32/18639 0.0625 1.12663201160542 0.53659403858032 0.79264048881485 GO:0140142 nucleocytoplasmic carrier activity 2/1034 32/18639 0.0625 1.12663201160542 0.53659403858032 0.79264048881485 GO:0016279 protein-lysine N-methyltransferase activity 4/1034 69/18639 0.0579710144927536 1.04499201076444 0.537294804422052 0.79264048881485 GO:0003743 translation initiation factor activity 3/1034 51/18639 0.0588235294117647 1.06035954033451 0.543343714408873 0.79264048881485 GO:0008028 monocarboxylic acid transmembrane transporter activity 4/1034 70/18639 0.0571428571428571 1.03006355346781 0.548792110725933 0.79264048881485 GO:0016278 lysine N-methyltransferase activity 4/1034 70/18639 0.0571428571428571 1.03006355346781 0.548792110725933 0.79264048881485 GO:0019955 cytokine binding 8/1034 144/18639 0.0555555555555556 1.00145067698259 0.549898116584819 0.79264048881485 GO:0004705 JUN kinase activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.79264048881485 GO:0005545 1-phosphatidylinositol binding 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.79264048881485 GO:0008174 mRNA methyltransferase activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.79264048881485 GO:0008474 palmitoyl-(protein) hydrolase activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.79264048881485 GO:0008559 ABC-type xenobiotic transporter activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.79264048881485 GO:0015386 potassium:proton antiporter activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.79264048881485 GO:0015926 glucosidase activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.79264048881485 GO:0016530 metallochaperone activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.79264048881485 GO:0042813 Wnt receptor activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.79264048881485 GO:0043176 amine binding 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.79264048881485 GO:0046030 inositol trisphosphate phosphatase activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.79264048881485 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.79264048881485 GO:0098599 palmitoyl hydrolase activity 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.79264048881485 GO:1901612 cardiolipin binding 1/1034 14/18639 0.0714285714285714 1.28757944183476 0.550361697894085 0.79264048881485 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 10/1034 181/18639 0.0552486187845304 0.99591780031418 0.551521078209783 0.793232486977435 GO:0016829 lyase activity 11/1034 200/18639 0.055 0.991436170212766 0.555800510154785 0.798304255777876 GO:0004864 protein phosphatase inhibitor activity 3/1034 53/18639 0.0566037735849057 1.02034597277472 0.56971067948567 0.803483027672521 GO:0005246 calcium channel regulator activity 3/1034 53/18639 0.0566037735849057 1.02034597277472 0.56971067948567 0.803483027672521 GO:0008376 acetylgalactosaminyltransferase activity 2/1034 34/18639 0.0588235294117647 1.06035954033451 0.569763015141806 0.803483027672521 GO:0090482 vitamin transmembrane transporter activity 2/1034 34/18639 0.0588235294117647 1.06035954033451 0.569763015141806 0.803483027672521 GO:0004559 alpha-mannosidase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0005041 low-density lipoprotein particle receptor activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0008252 nucleotidase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0010181 FMN binding 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0015250 water channel activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0017081 chloride channel regulator activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0033130 acetylcholine receptor binding 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0034483 heparan sulfate sulfotransferase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0042809 nuclear vitamin D receptor binding 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0045504 dynein heavy chain binding 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0047372 monoacylglycerol lipase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0051371 muscle alpha-actinin binding 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0061578 K63-linked deubiquitinase activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0120283 protein serine/threonine kinase binding 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0140161 monocarboxylate:sodium symporter activity 1/1034 15/18639 0.0666666666666667 1.20174081237911 0.575324167927777 0.803483027672521 GO:0015078 proton transmembrane transporter activity 10/1034 185/18639 0.0540540540540541 0.974384442469549 0.579651689828892 0.808461567392928 GO:0043178 alcohol binding 5/1034 92/18639 0.0543478260869565 0.979680010091666 0.583394976352316 0.808688736335012 GO:0016874 ligase activity 9/1034 167/18639 0.0538922155688623 0.97146712377952 0.583966223156869 0.808688736335012 GO:0001664 G protein-coupled receptor binding 16/1034 297/18639 0.0538720538720539 0.971103686770998 0.584875264768021 0.808688736335012 GO:0005343 organic acid:sodium symporter activity 2/1034 35/18639 0.0571428571428571 1.03006355346781 0.585690109230375 0.808688736335012 GO:0043015 gamma-tubulin binding 2/1034 35/18639 0.0571428571428571 1.03006355346781 0.585690109230375 0.808688736335012 GO:0140566 histone reader activity 2/1034 35/18639 0.0571428571428571 1.03006355346781 0.585690109230375 0.808688736335012 GO:0005539 glycosaminoglycan binding 13/1034 242/18639 0.0537190082644628 0.968344869479035 0.588063138025559 0.808688736335012 GO:0035064 methylated histone binding 4/1034 74/18639 0.0540540540540541 0.974384442469549 0.593217761481915 0.808688736335012 GO:0005200 structural constituent of cytoskeleton 6/1034 112/18639 0.0535714285714286 0.965684581376071 0.593855249636664 0.808688736335012 GO:0008374 O-acyltransferase activity 3/1034 55/18639 0.0545454545454545 0.983242482855636 0.59511517164188 0.808688736335012 GO:0140097 catalytic activity, acting on DNA 18/1034 336/18639 0.0535714285714286 0.965684581376071 0.595500031690991 0.808688736335012 GO:0000062 fatty-acyl-CoA binding 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.808688736335012 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.808688736335012 GO:0004707 MAP kinase activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.808688736335012 GO:0005149 interleukin-1 receptor binding 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.808688736335012 GO:0005521 lamin binding 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.808688736335012 GO:0008142 oxysterol binding 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.808688736335012 GO:0008296 3'-5'-DNA exonuclease activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.808688736335012 GO:0015378 sodium:chloride symporter activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.808688736335012 GO:0015923 mannosidase activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.808688736335012 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.808688736335012 GO:0055102 lipase inhibitor activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.808688736335012 GO:0097027 ubiquitin-protein transferase activator activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.808688736335012 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.808688736335012 GO:0140327 flippase activity 1/1034 16/18639 0.0625 1.12663201160542 0.598902067968728 0.808688736335012 GO:0004190 aspartic-type endopeptidase activity 2/1034 36/18639 0.0555555555555556 1.00145067698259 0.601176154935839 0.808688736335012 GO:0045505 dynein intermediate chain binding 2/1034 36/18639 0.0555555555555556 1.00145067698259 0.601176154935839 0.808688736335012 GO:0055106 ubiquitin-protein transferase regulator activity 2/1034 36/18639 0.0555555555555556 1.00145067698259 0.601176154935839 0.808688736335012 GO:0019212 phosphatase inhibitor activity 3/1034 56/18639 0.0535714285714286 0.965684581376071 0.6074451178213 0.810889719100466 GO:0140034 methylation-dependent protein binding 4/1034 76/18639 0.0526315789473684 0.948742746615087 0.614432205166377 0.810889719100466 GO:0004518 nuclease activity 11/1034 209/18639 0.0526315789473684 0.948742746615087 0.614947979964974 0.810889719100466 GO:0022829 wide pore channel activity 2/1034 37/18639 0.0540540540540541 0.974384442469549 0.61622102654221 0.810889719100466 GO:0042805 actinin binding 2/1034 37/18639 0.0540540540540541 0.974384442469549 0.61622102654221 0.810889719100466 GO:0070001 aspartic-type peptidase activity 2/1034 37/18639 0.0540540540540541 0.974384442469549 0.61622102654221 0.810889719100466 GO:0004601 peroxidase activity 3/1034 57/18639 0.0526315789473684 0.948742746615087 0.619522317072613 0.810889719100466 GO:0015932 nucleobase-containing compound transmembrane transporter activity 3/1034 57/18639 0.0526315789473684 0.948742746615087 0.619522317072613 0.810889719100466 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.810889719100466 GO:0004549 tRNA-specific ribonuclease activity 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.810889719100466 GO:0004550 nucleoside diphosphate kinase activity 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.810889719100466 GO:0004659 prenyltransferase activity 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.810889719100466 GO:0005092 GDP-dissociation inhibitor activity 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.810889719100466 GO:0008484 sulfuric ester hydrolase activity 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.810889719100466 GO:0016805 dipeptidase activity 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.810889719100466 GO:0030548 acetylcholine receptor regulator activity 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.810889719100466 GO:0031489 myosin V binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.810889719100466 GO:0032183 SUMO binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.810889719100466 GO:0038191 neuropilin binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.810889719100466 GO:0070402 NADPH binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.810889719100466 GO:0070403 NAD+ binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.810889719100466 GO:0070492 oligosaccharide binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.810889719100466 GO:1901567 fatty acid derivative binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.810889719100466 GO:1990226 histone methyltransferase binding 1/1034 17/18639 0.0588235294117647 1.06035954033451 0.621172124442998 0.810889719100466 GO:0005109 frizzled binding 2/1034 38/18639 0.0526315789473684 0.948742746615087 0.63082596833847 0.820460768636538 GO:0005501 retinoid binding 2/1034 38/18639 0.0526315789473684 0.948742746615087 0.63082596833847 0.820460768636538 GO:0019840 isoprenoid binding 2/1034 38/18639 0.0526315789473684 0.948742746615087 0.63082596833847 0.820460768636538 GO:0008170 N-methyltransferase activity 5/1034 98/18639 0.0510204081632653 0.919699601310544 0.639618353047257 0.822054895012222 GO:0003746 translation elongation factor activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.822054895012222 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.822054895012222 GO:0005372 water transmembrane transporter activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.822054895012222 GO:0015172 acidic amino acid transmembrane transporter activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.822054895012222 GO:0015373 monoatomic anion:sodium symporter activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.822054895012222 GO:0017075 syntaxin-1 binding 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.822054895012222 GO:0030228 lipoprotein particle receptor activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.822054895012222 GO:0034185 apolipoprotein binding 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.822054895012222 GO:0035615 clathrin adaptor activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.822054895012222 GO:0098641 cadherin binding involved in cell-cell adhesion 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.822054895012222 GO:0099602 neurotransmitter receptor regulator activity 1/1034 18/18639 0.0555555555555556 1.00145067698259 0.642206815847033 0.822054895012222 GO:0015459 potassium channel regulator activity 3/1034 59/18639 0.0508474576271186 0.916581975543389 0.642908969778427 0.822054895012222 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/1034 59/18639 0.0508474576271186 0.916581975543389 0.642908969778427 0.822054895012222 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/1034 39/18639 0.0512820512820513 0.924416009522392 0.644993443280827 0.823726566117683 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/1034 40/18639 0.05 0.901305609284333 0.658726994202878 0.831515502583199 GO:0140098 catalytic activity, acting on RNA 20/1034 387/18639 0.0516795865633075 0.931582025100085 0.661161834130367 0.831515502583199 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.831515502583199 GO:0005229 intracellularly calcium-gated chloride channel activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.831515502583199 GO:0008574 plus-end-directed microtubule motor activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.831515502583199 GO:0030506 ankyrin binding 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.831515502583199 GO:0042800 histone H3K4 methyltransferase activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.831515502583199 GO:0046624 sphingolipid transporter activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.831515502583199 GO:0050145 nucleoside monophosphate kinase activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.831515502583199 GO:0070003 threonine-type peptidase activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.831515502583199 GO:0097001 ceramide binding 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.831515502583199 GO:0120227 acyl-CoA binding 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.831515502583199 GO:0141147 intracellularly calcium-gated channel activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.831515502583199 GO:1990380 K48-linked deubiquitinase activity 1/1034 19/18639 0.0526315789473684 0.948742746615087 0.662074607717189 0.831515502583199 GO:0099106 ion channel regulator activity 8/1034 160/18639 0.05 0.901305609284333 0.668814023756336 0.838985639268303 GO:0001727 lipid kinase activity 2/1034 41/18639 0.0487804878048781 0.879322545643251 0.672031116649366 0.840152019896324 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 2/1034 41/18639 0.0487804878048781 0.879322545643251 0.672031116649366 0.840152019896324 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 25/1034 484/18639 0.0516528925619835 0.931100836037534 0.673811030085974 0.840152019896324 GO:0001614 purinergic nucleotide receptor activity 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.840152019896324 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.840152019896324 GO:0005326 neurotransmitter transmembrane transporter activity 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.840152019896324 GO:0015095 magnesium ion transmembrane transporter activity 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.840152019896324 GO:0016408 C-acyltransferase activity 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.840152019896324 GO:0016502 nucleotide receptor activity 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.840152019896324 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.840152019896324 GO:0030742 GTP-dependent protein binding 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.840152019896324 GO:0031418 L-ascorbic acid binding 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.840152019896324 GO:0052745 inositol phosphate phosphatase activity 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.840152019896324 GO:0140939 histone H4 methyltransferase activity 1/1034 20/18639 0.05 0.901305609284333 0.680840174614097 0.840152019896324 GO:0008307 structural constituent of muscle 2/1034 42/18639 0.0476190476190476 0.858386294556507 0.68491114247297 0.844192803513196 GO:0004527 exonuclease activity 4/1034 84/18639 0.0476190476190476 0.858386294556507 0.692117807929435 0.8520846415856 GO:0005245 voltage-gated calcium channel activity 2/1034 43/18639 0.0465116279069767 0.838423822590077 0.697373133393152 0.852104127076115 GO:0061135 endopeptidase regulator activity 9/1034 184/18639 0.0489130434782609 0.881712009082499 0.698033924362994 0.852104127076115 GO:0008373 sialyltransferase activity 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.852104127076115 GO:0010314 phosphatidylinositol-5-phosphate binding 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.852104127076115 GO:0015125 bile acid transmembrane transporter activity 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.852104127076115 GO:0015174 basic amino acid transmembrane transporter activity 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.852104127076115 GO:0035613 RNA stem-loop binding 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.852104127076115 GO:0070182 DNA polymerase binding 1/1034 21/18639 0.0476190476190476 0.858386294556507 0.698564609838815 0.852104127076115 GO:0008194 UDP-glycosyltransferase activity 7/1034 145/18639 0.0482758620689655 0.870226105515907 0.699974712064099 0.852842752629822 GO:0001216 DNA-binding transcription activator activity 25/1034 491/18639 0.0509164969450102 0.917826486032925 0.700942108875093 0.853040913211939 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/1034 86/18639 0.0465116279069767 0.838423822590077 0.70969257772245 0.862699693102979 GO:0008093 cytoskeletal anchor activity 1/1034 22/18639 0.0454545454545455 0.81936873571303 0.715305623558155 0.865552466862607 GO:0031683 G-protein beta/gamma-subunit complex binding 1/1034 22/18639 0.0454545454545455 0.81936873571303 0.715305623558155 0.865552466862607 GO:0034062 5'-3' RNA polymerase activity 1/1034 22/18639 0.0454545454545455 0.81936873571303 0.715305623558155 0.865552466862607 GO:0097747 RNA polymerase activity 1/1034 22/18639 0.0454545454545455 0.81936873571303 0.715305623558155 0.865552466862607 GO:0005516 calmodulin binding 10/1034 207/18639 0.0483091787439614 0.870826675637036 0.717931259934696 0.86707640922396 GO:0008081 phosphoric diester hydrolase activity 4/1034 87/18639 0.0459770114942529 0.828786767158007 0.718201025753431 0.86707640922396 GO:0046943 carboxylic acid transmembrane transporter activity 9/1034 188/18639 0.0478723404255319 0.862952179102021 0.721779765506996 0.870405633034602 GO:0005342 organic acid transmembrane transporter activity 9/1034 189/18639 0.0476190476190476 0.858386294556507 0.727519624292387 0.872201919086916 GO:0004620 phospholipase activity 5/1034 109/18639 0.0458715596330275 0.826885880077369 0.729633428026593 0.872201919086916 GO:0003887 DNA-directed DNA polymerase activity 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.872201919086916 GO:0016493 C-C chemokine receptor activity 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.872201919086916 GO:0031681 G-protein beta-subunit binding 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.872201919086916 GO:0043274 phospholipase binding 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.872201919086916 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.872201919086916 GO:0099186 structural constituent of postsynapse 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.872201919086916 GO:0140103 catalytic activity, acting on a glycoprotein 1/1034 23/18639 0.0434782608695652 0.783744008073333 0.731117729979214 0.872201919086916 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/1034 46/18639 0.0434782608695652 0.783744008073333 0.732320479233354 0.872201919086916 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/1034 46/18639 0.0434782608695652 0.783744008073333 0.732320479233354 0.872201919086916 GO:0008094 ATP-dependent activity, acting on DNA 10/1034 210/18639 0.0476190476190476 0.858386294556507 0.734288804047348 0.872864867139628 GO:0004222 metalloendopeptidase activity 5/1034 110/18639 0.0454545454545455 0.81936873571303 0.736945188502925 0.872864867139628 GO:0005262 calcium channel activity 6/1034 131/18639 0.0458015267175573 0.825623458886412 0.740674941552416 0.872864867139628 GO:1902936 phosphatidylinositol bisphosphate binding 5/1034 111/18639 0.045045045045045 0.811987035391291 0.744111486166322 0.872864867139628 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.872864867139628 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.872864867139628 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.872864867139628 GO:0005540 hyaluronic acid binding 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.872864867139628 GO:0019957 C-C chemokine binding 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.872864867139628 GO:0030215 semaphorin receptor binding 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.872864867139628 GO:0030552 cAMP binding 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.872864867139628 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.872864867139628 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.872864867139628 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.872864867139628 GO:0050699 WW domain binding 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.872864867139628 GO:0140612 DNA damage sensor activity 1/1034 24/18639 0.0416666666666667 0.751088007736944 0.746052424177833 0.872864867139628 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 4/1034 91/18639 0.043956043956044 0.792356579590622 0.750389110140351 0.876004908313626 GO:0072341 modified amino acid binding 4/1034 91/18639 0.043956043956044 0.792356579590622 0.750389110140351 0.876004908313626 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/1034 48/18639 0.0416666666666667 0.751088007736944 0.753664258151789 0.878860411046091 GO:0005125 cytokine activity 11/1034 234/18639 0.047008547008547 0.847381342062193 0.755659023629636 0.880218203348807 GO:0003707 nuclear steroid receptor activity 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.88158408107381 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.88158408107381 GO:0047617 fatty acyl-CoA hydrolase activity 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.88158408107381 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/1034 25/18639 0.04 0.721044487427466 0.760158349152323 0.88158408107381 GO:0035401 histone H3Y41 kinase activity 5/1034 115/18639 0.0434782608695652 0.783744008073333 0.771333666115802 0.881602517054668 GO:0140801 histone H2AXY142 kinase activity 5/1034 115/18639 0.0434782608695652 0.783744008073333 0.771333666115802 0.881602517054668 GO:0019838 growth factor binding 6/1034 136/18639 0.0441176470588235 0.795269655250882 0.77220856004273 0.881602517054668 GO:0042562 hormone binding 4/1034 94/18639 0.0425531914893617 0.767068603646241 0.772622991726277 0.881602517054668 GO:0001637 G protein-coupled chemoattractant receptor activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.881602517054668 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.881602517054668 GO:0004435 phosphatidylinositol phospholipase C activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.881602517054668 GO:0004529 DNA exonuclease activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.881602517054668 GO:0004950 chemokine receptor activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.881602517054668 GO:0008143 poly(A) binding 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.881602517054668 GO:0016289 acyl-CoA hydrolase activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.881602517054668 GO:0034237 protein kinase A regulatory subunit binding 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.881602517054668 GO:0043548 phosphatidylinositol 3-kinase binding 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.881602517054668 GO:0052742 phosphatidylinositol kinase activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.881602517054668 GO:0097602 cullin family protein binding 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.881602517054668 GO:0120014 phospholipid transfer activity 1/1034 26/18639 0.0384615384615385 0.693312007141794 0.773481453642303 0.881602517054668 GO:0004521 RNA endonuclease activity 3/1034 73/18639 0.0410958904109589 0.74079913091863 0.777966342394833 0.885761893596695 GO:0008276 protein methyltransferase activity 4/1034 95/18639 0.0421052631578947 0.75899419729207 0.779678971037717 0.886759344742468 GO:0031491 nucleosome binding 3/1034 74/18639 0.0405405405405405 0.730788331852162 0.785772620461576 0.890201976171002 GO:0005044 scavenger receptor activity 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.890201976171002 GO:0005104 fibroblast growth factor receptor binding 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.890201976171002 GO:0008395 steroid hydroxylase activity 1/1034 27/18639 0.037037037037037 0.667633784655061 0.786065141222697 0.890201976171002 GO:0005080 protein kinase C binding 2/1034 52/18639 0.0384615384615385 0.693312007141794 0.791969396061598 0.895931227134785 GO:0004866 endopeptidase inhibitor activity 7/1034 161/18639 0.0434782608695652 0.783744008073333 0.795848922158877 0.897173942507792 GO:0045499 chemorepellent activity 1/1034 28/18639 0.0357142857142857 0.643789720917381 0.797950411154769 0.897173942507792 GO:0050698 proteoglycan sulfotransferase activity 1/1034 28/18639 0.0357142857142857 0.643789720917381 0.797950411154769 0.897173942507792 GO:0051537 2 iron, 2 sulfur cluster binding 1/1034 28/18639 0.0357142857142857 0.643789720917381 0.797950411154769 0.897173942507792 GO:0005544 calcium-dependent phospholipid binding 2/1034 53/18639 0.0377358490566038 0.680230648516478 0.800685424162615 0.897173942507792 GO:0008146 sulfotransferase activity 2/1034 53/18639 0.0377358490566038 0.680230648516478 0.800685424162615 0.897173942507792 GO:0017046 peptide hormone binding 2/1034 53/18639 0.0377358490566038 0.680230648516478 0.800685424162615 0.897173942507792 GO:0051018 protein kinase A binding 2/1034 53/18639 0.0377358490566038 0.680230648516478 0.800685424162615 0.897173942507792 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/1034 53/18639 0.0377358490566038 0.680230648516478 0.800685424162615 0.897173942507792 GO:0004175 endopeptidase activity 19/1034 405/18639 0.0469135802469136 0.845669460563078 0.806154168640372 0.900027860374094 GO:0050661 NADP binding 2/1034 54/18639 0.037037037037037 0.667633784655061 0.809075797951114 0.900027860374094 GO:0051287 NAD binding 2/1034 54/18639 0.037037037037037 0.667633784655061 0.809075797951114 0.900027860374094 GO:0004181 metallocarboxypeptidase activity 1/1034 29/18639 0.0344827586206897 0.621590075368505 0.809175991449539 0.900027860374094 GO:0004629 phospholipase C activity 1/1034 29/18639 0.0344827586206897 0.621590075368505 0.809175991449539 0.900027860374094 GO:0051861 glycolipid binding 1/1034 29/18639 0.0344827586206897 0.621590075368505 0.809175991449539 0.900027860374094 GO:0099604 ligand-gated calcium channel activity 1/1034 29/18639 0.0344827586206897 0.621590075368505 0.809175991449539 0.900027860374094 GO:0008514 organic anion transmembrane transporter activity 12/1034 269/18639 0.0446096654275093 0.80413883356223 0.819535065743376 0.90991117533838 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/1034 30/18639 0.0333333333333333 0.600870406189555 0.819778464573729 0.90991117533838 GO:0015370 solute:sodium symporter activity 3/1034 79/18639 0.0379746835443038 0.684535905785569 0.821453987056915 0.9108171823016 GO:0046873 metal ion transmembrane transporter activity 21/1034 450/18639 0.0466666666666667 0.841218568665377 0.823159482148017 0.911754494333227 GO:0005164 tumor necrosis factor receptor binding 1/1034 31/18639 0.032258064516129 0.58148748986086 0.829792386204702 0.915275680933386 GO:0005452 solute:inorganic anion antiporter activity 1/1034 31/18639 0.032258064516129 0.58148748986086 0.829792386204702 0.915275680933386 GO:0017147 Wnt-protein binding 1/1034 31/18639 0.032258064516129 0.58148748986086 0.829792386204702 0.915275680933386 GO:0047499 calcium-independent phospholipase A2 activity 1/1034 31/18639 0.032258064516129 0.58148748986086 0.829792386204702 0.915275680933386 GO:0030414 peptidase inhibitor activity 7/1034 169/18639 0.0414201183431953 0.746643699998855 0.834162193112616 0.919139214864213 GO:0042910 xenobiotic transmembrane transporter activity 1/1034 32/18639 0.03125 0.563316005802708 0.839250397418391 0.919964241223883 GO:0043425 bHLH transcription factor binding 1/1034 32/18639 0.03125 0.563316005802708 0.839250397418391 0.919964241223883 GO:0047498 calcium-dependent phospholipase A2 activity 1/1034 32/18639 0.03125 0.563316005802708 0.839250397418391 0.919964241223883 GO:0071813 lipoprotein particle binding 1/1034 32/18639 0.03125 0.563316005802708 0.839250397418391 0.919964241223883 GO:0071814 protein-lipid complex binding 1/1034 32/18639 0.03125 0.563316005802708 0.839250397418391 0.919964241223883 GO:0030165 PDZ domain binding 3/1034 83/18639 0.036144578313253 0.651546223579036 0.846232107194656 0.925958442483179 GO:0001786 phosphatidylserine binding 2/1034 59/18639 0.0338983050847458 0.611054650362259 0.846465783741699 0.925958442483179 GO:0019239 deaminase activity 1/1034 33/18639 0.0303030303030303 0.546245823808687 0.848183330673047 0.926880753106629 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/1034 60/18639 0.0333333333333333 0.600870406189555 0.853095112592572 0.930345828409287 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 5/1034 130/18639 0.0384615384615385 0.693312007141794 0.853927266984817 0.930345828409287 GO:0003823 antigen binding 7/1034 174/18639 0.0402298850574713 0.725188421263256 0.855063350770237 0.930345828409287 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/1034 34/18639 0.0294117647058824 0.530179770167255 0.85662030993157 0.930345828409287 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/1034 34/18639 0.0294117647058824 0.530179770167255 0.85662030993157 0.930345828409287 GO:0051427 hormone receptor binding 1/1034 34/18639 0.0294117647058824 0.530179770167255 0.85662030993157 0.930345828409287 GO:0004623 phospholipase A2 activity 1/1034 35/18639 0.0285714285714286 0.515031776733904 0.864588845246311 0.938039074678699 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/1034 36/18639 0.0277777777777778 0.500725338491296 0.872114922112324 0.944271519345315 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/1034 36/18639 0.0277777777777778 0.500725338491296 0.872114922112324 0.944271519345315 GO:0004536 DNA nuclease activity 2/1034 64/18639 0.03125 0.563316005802708 0.877076953676487 0.948675072343955 GO:0030551 cyclic nucleotide binding 1/1034 37/18639 0.027027027027027 0.487192221234774 0.879223085878161 0.949059542801273 GO:0043394 proteoglycan binding 1/1034 37/18639 0.027027027027027 0.487192221234774 0.879223085878161 0.949059542801273 GO:0019843 rRNA binding 2/1034 65/18639 0.0307692307692308 0.554649605713435 0.882480594596268 0.951606744935955 GO:0008083 growth factor activity 6/1034 162/18639 0.037037037037037 0.667633784655061 0.891398471379895 0.960246320795415 GO:0015081 sodium ion transmembrane transporter activity 6/1034 164/18639 0.0365853658536585 0.659491909232439 0.897841004286509 0.965681064326939 GO:0015144 carbohydrate transmembrane transporter activity 1/1034 40/18639 0.025 0.450652804642166 0.898265593798455 0.965681064326939 GO:0004867 serine-type endopeptidase inhibitor activity 3/1034 95/18639 0.0315789473684211 0.569245647969052 0.903450215268249 0.967835094010922 GO:0001530 lipopolysaccharide binding 1/1034 41/18639 0.024390243902439 0.439661272821626 0.903921455727182 0.967835094010922 GO:0004812 aminoacyl-tRNA ligase activity 1/1034 41/18639 0.024390243902439 0.439661272821626 0.903921455727182 0.967835094010922 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/1034 41/18639 0.024390243902439 0.439661272821626 0.903921455727182 0.967835094010922 GO:0016782 transferase activity, transferring sulphur-containing groups 2/1034 70/18639 0.0285714285714286 0.515031776733904 0.906344670195644 0.969450404043777 GO:0004520 DNA endonuclease activity 1/1034 42/18639 0.0238095238095238 0.429193147278254 0.909263170684602 0.970613253701589 GO:0031492 nucleosomal DNA binding 1/1034 42/18639 0.0238095238095238 0.429193147278254 0.909263170684602 0.970613253701589 GO:0140299 molecular sensor activity 2/1034 71/18639 0.028169014084507 0.507777808047511 0.910538645829531 0.970996946256844 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/1034 43/18639 0.0232558139534884 0.419211911295038 0.914308171572494 0.97403684609733 GO:0016790 thiolester hydrolase activity 1/1034 44/18639 0.0227272727272727 0.409684367856515 0.919072924777164 0.978129819541961 GO:0008201 heparin binding 6/1034 172/18639 0.0348837209302326 0.628817866942558 0.920435513205701 0.978597436306964 GO:0008509 monoatomic anion transmembrane transporter activity 5/1034 149/18639 0.0335570469798658 0.604903093479418 0.921394585590271 0.978635531789265 GO:0051539 4 iron, 4 sulfur cluster binding 1/1034 45/18639 0.0222222222222222 0.400580270793037 0.92357298370593 0.979967330058344 GO:0004519 endonuclease activity 4/1034 127/18639 0.031496062992126 0.567751564903517 0.926973719862485 0.982592143054234 GO:0051536 iron-sulfur cluster binding 2/1034 76/18639 0.0263157894736842 0.474371373307544 0.928990962836153 0.982773461590133 GO:0061749 forked DNA-dependent helicase activity 1/1034 47/18639 0.0212765957446809 0.38353430182312 0.931836968113679 0.982773461590133 GO:0099095 ligand-gated monoatomic anion channel activity 1/1034 47/18639 0.0212765957446809 0.38353430182312 0.931836968113679 0.982773461590133 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/1034 47/18639 0.0212765957446809 0.38353430182312 0.931836968113679 0.982773461590133 GO:0051540 metal cluster binding 2/1034 77/18639 0.025974025974026 0.468210706121731 0.932221786536384 0.982773461590133 GO:0019199 transmembrane receptor protein kinase activity 2/1034 78/18639 0.0256410256410256 0.462208004761196 0.935313131997972 0.982773461590133 GO:0009378 four-way junction helicase activity 1/1034 48/18639 0.0208333333333333 0.375544003868472 0.935627876836272 0.982773461590133 GO:0036121 double-stranded DNA helicase activity 1/1034 48/18639 0.0208333333333333 0.375544003868472 0.935627876836272 0.982773461590133 GO:0043138 3'-5' DNA helicase activity 1/1034 48/18639 0.0208333333333333 0.375544003868472 0.935627876836272 0.982773461590133 GO:0004497 monooxygenase activity 3/1034 106/18639 0.0283018867924528 0.510172986387358 0.938195365487735 0.982773461590133 GO:0008013 beta-catenin binding 3/1034 106/18639 0.0283018867924528 0.510172986387358 0.938195365487735 0.982773461590133 GO:0016835 carbon-oxygen lyase activity 2/1034 79/18639 0.0253164556962025 0.456357270523713 0.938270512386051 0.982773461590133 GO:0005007 fibroblast growth factor receptor activity 1/1034 50/18639 0.02 0.360522243713733 0.942589467616309 0.985349936561428 GO:0032813 tumor necrosis factor receptor superfamily binding 1/1034 50/18639 0.02 0.360522243713733 0.942589467616309 0.985349936561428 GO:1901681 sulfur compound binding 10/1034 275/18639 0.0363636363636364 0.655494988570424 0.944394624261473 0.985771741613961 GO:0005010 insulin-like growth factor receptor activity 1/1034 51/18639 0.0196078431372549 0.353453180111503 0.945782887944715 0.985771741613961 GO:0016597 amino acid binding 1/1034 51/18639 0.0196078431372549 0.353453180111503 0.945782887944715 0.985771741613961 GO:0038064 collagen receptor activity 1/1034 53/18639 0.0188679245283019 0.340115324258239 0.951647173662171 0.990909630728783 GO:0015103 inorganic anion transmembrane transporter activity 5/1034 165/18639 0.0303030303030303 0.546245823808687 0.95508187834686 0.993510099163564 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 5/1034 167/18639 0.029940119760479 0.539703957655289 0.958206123838548 0.995782834577315 GO:0170055 lipid transmembrane transporter activity 1/1034 56/18639 0.0178571428571429 0.32189486045869 0.959276999754532 0.995919314142805 GO:0008236 serine-type peptidase activity 6/1034 194/18639 0.0309278350515464 0.557508624299587 0.961566105011112 0.997319052164167 GO:0017116 single-stranded DNA helicase activity 1/1034 58/18639 0.0172413793103448 0.310795037684253 0.96368287306283 0.99853748333001 GO:0017171 serine hydrolase activity 6/1034 198/18639 0.0303030303030303 0.546245823808687 0.96652217882615 0.998619904473435 GO:0052689 carboxylic ester hydrolase activity 2/1034 92/18639 0.0217391304347826 0.391872004036666 0.966718582531563 0.998619904473435 GO:0015108 chloride transmembrane transporter activity 3/1034 121/18639 0.0247933884297521 0.446928401298016 0.967180685124676 0.998619904473435 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/1034 60/18639 0.0166666666666667 0.300435203094778 0.967612480154164 0.998619904473435 GO:0008528 G protein-coupled peptide receptor activity 3/1034 122/18639 0.0245901639344262 0.443265053746393 0.968564669846203 0.998619904473435 GO:0016836 hydro-lyase activity 1/1034 61/18639 0.0163934426229508 0.295510035830929 0.969414982738834 0.998619904473435 GO:0046906 tetrapyrrole binding 4/1034 152/18639 0.0263157894736842 0.474371373307544 0.972140403823901 0.999999999185046 GO:0001653 peptide receptor activity 3/1034 128/18639 0.0234375 0.422487004352031 0.975776639414085 0.999999999185046 GO:0008173 RNA methyltransferase activity 1/1034 67/18639 0.0149253731343284 0.269046450532637 0.978309676970525 0.999999999185046 GO:0016500 protein-hormone receptor activity 1/1034 67/18639 0.0149253731343284 0.269046450532637 0.978309676970525 0.999999999185046 GO:0005253 monoatomic anion channel activity 2/1034 103/18639 0.0194174757281553 0.350021595838576 0.98049737474235 0.999999999185046 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/1034 73/18639 0.0136986301369863 0.246933043639543 0.984619385757109 0.999999999185046 GO:0140101 catalytic activity, acting on a tRNA 3/1034 139/18639 0.0215827338129496 0.389052780986043 0.985107859136184 0.999999999185046 GO:0003678 DNA helicase activity 1/1034 74/18639 0.0135135135135135 0.243596110617387 0.985475981422689 0.999999999185046 GO:0020037 heme binding 3/1034 142/18639 0.0211267605633803 0.380833356035634 0.986981652301185 0.999999999185046 GO:0017022 myosin binding 1/1034 76/18639 0.0131578947368421 0.237185686653772 0.987048833453168 0.999999999185046 GO:0008168 methyltransferase activity 5/1034 204/18639 0.0245098039215686 0.441816475139379 0.989758118757665 0.999999999185046 GO:0005254 chloride channel activity 1/1034 83/18639 0.0120481927710843 0.217182074526345 0.991329528112657 0.999999999185046 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/1034 122/18639 0.0163934426229508 0.295510035830929 0.992405460661408 0.999999999185046 GO:0016741 transferase activity, transferring one-carbon groups 5/1034 215/18639 0.0232558139534884 0.419211911295038 0.99341096237552 0.999999999185046 GO:0015079 potassium ion transmembrane transporter activity 3/1034 160/18639 0.01875 0.337989603481625 0.994272789430885 0.999999999185046 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/1034 132/18639 0.0151515151515152 0.273122911904343 0.995415382522678 0.999999999185046 GO:0022832 voltage-gated channel activity 3/1034 175/18639 0.0171428571428571 0.309019066040343 0.997158006108731 0.999999999185046 GO:0022843 voltage-gated monoatomic cation channel activity 2/1034 143/18639 0.013986013986014 0.252113457142471 0.997383196362585 0.999999999185046 GO:0005244 voltage-gated monoatomic ion channel activity 2/1034 173/18639 0.0115606936416185 0.208394360528169 0.999446634157123 0.999999999185046 GO:0004252 serine-type endopeptidase activity 2/1034 176/18639 0.0113636363636364 0.204842183928257 0.999527057628707 0.999999999185046 GO:0099094 ligand-gated monoatomic cation channel activity 1/1034 136/18639 0.00735294117647059 0.132544942541814 0.999586572493916 0.999999999185046 GO:0005261 monoatomic cation channel activity 7/1034 341/18639 0.0205278592375367 0.37003749354782 0.999612454427892 0.999999999185046 GO:0015276 ligand-gated monoatomic ion channel activity 2/1034 186/18639 0.010752688172043 0.193829163286953 0.999720339876887 0.999999999185046 GO:0022834 ligand-gated channel activity 2/1034 188/18639 0.0106382978723404 0.19176715091156 0.999748320176476 0.999999999185046 GO:0022836 gated channel activity 5/1034 318/18639 0.0157232704402516 0.283429436881866 0.999925715802188 0.999999999185046 GO:0005201 extracellular matrix structural constituent 1/1034 168/18639 0.00595238095238095 0.107298286819563 0.999934455215062 0.999999999185046 GO:0005216 monoatomic ion channel activity 9/1034 448/18639 0.0200892857142857 0.362131718016027 0.999948779635356 0.999999999185046 GO:0030371 translation repressor activity 5/1034 329/18639 0.0151975683890578 0.2739530727308 0.999955303836612 0.999999999185046 GO:0003730 mRNA 3'-UTR binding 3/1034 262/18639 0.0114503816793893 0.206405864721603 0.999960317138167 0.999999999185046 GO:0045182 translation regulator activity 5/1034 356/18639 0.0140449438202247 0.253175732945037 0.999987384594364 0.999999999185046 GO:0004984 olfactory receptor activity 2/1034 419/18639 0.00477326968973747 0.0860434949197454 0.999999999185046 0.999999999185046