category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	20/181	187/9376	5.54022513073537	NAMPT/NAIP/CXCL8/GABARAP/IFI16/IRF9/OAS3/CARD16/OAS2/MAP1LC3B/OAS1/STAT1/CXCL1/CASP1/TNFAIP3/BIRC2/NLRP12/AIM2/TXN/CARD8	8.79859088802139
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	19/181	196/9376	5.02153568609764	HIF1A/CCR1/CXCL8/PLCG2/EIF2AK2/CLEC2B/IRF9/MAP1LC3B/STAT1/CXCL1/ZFP36/KRAS/PREX1/GNG10/E2F3/HLA-C/IFNGR1/VEGFA/FOS	7.98266089596872
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	17/181	180/9376	4.89232658072437	ZC3HAV1/EIF2AK2/IRF9/B2M/OAS3/OAS2/OAS1/STAT1/SP100/TLR2/IFIH1/HLA-C/BIRC2/IFNGR1/TNFSF14/PPP1CB/PML	7.39767252147442
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	19/181	238/9376	4.13538232972747	MX1/ISG15/MX2/CXCL8/PLCG2/ADAM17/EIF2AK2/CFD/IRF9/OAS3/OAS2/OAS1/STAT1/TLR2/CASP1/IFIH1/ADAR/FOS/TLR8	6.87388824193455
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	16/181	173/9376	4.79085363906365	MX1/RSAD2/MX2/CXCL8/EIF2AK2/IRF9/OAS3/OAS2/OAS1/STAT1/CASP1/IFIH1/IFNGR1/ADAR/TNFSF10/PML	7.0606456536129
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	14/181	156/9376	4.64881711290551	MX1/IFIT1/RSAD2/MX2/EIF2AK2/IRF9/OAS3/OAS2/OAS1/STAT1/KRAS/OCLN/E2F3/YWHAB	6.44759861863639
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	16/181	205/9376	4.04301307101469	ISG15/PLCG2/EIF2AK2/IRF9/B2M/OAS3/OAS2/CD58/OAS1/STAT1/TLR2/TNFAIP3/CD44/E2F3/HLA-C/MAP2K3	6.18046939930513
Human Diseases	Infectious disease: viral	hsa05162	Measles	13/181	136/9376	4.95157621059473	MX1/MX2/EIF2AK2/IRF9/OAS3/OAS2/OAS1/STAT1/TLR2/TNFAIP3/IFIH1/ADAR/FOS	6.5125772776406
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	11/181	119/9376	4.78833743442128	ADAM17/IL18R1/MAP3K8/CXCL1/TNFAIP3/EDN1/BIRC2/CREB5/MAP2K3/FOS/IRF1	5.83493554700298
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	10/181	100/9376	5.18011049723757	CCR1/CXCL8/IL18R1/CXCR2/CXCL1/CXCR4/IL18RAP/TNFSF14/TNFSF10/CCL3L1	5.89598609952076
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	10/181	105/9376	4.93343856879768	BCL2A1/CXCL8/PLCG2/TNFSF13B/LY96/CXCL1/TNFAIP3/PLAU/BIRC2/TNFSF14	5.68660142753967
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	10/181	109/9376	4.7523949515941	CXCL8/IRF9/MAP3K8/LY96/STAT1/TLR2/MAP2K3/FOS/CCL3L1/TLR8	5.5284230534469
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	7/181	56/9376	6.47513812154696	NAIP/CXCL8/TLR2/CXCL1/CASP1/RAB1A/SEC22B	5.76540998335099
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	12/181	169/9376	3.67818496845271	HIF1A/IRS2/SH3GLB1/GABARAP/MAP1LC3B/KRAS/WDFY3/PTEN/RAB1A/VMP1/RRAGC/VPS18	4.92917126174581
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	16/181	298/9376	2.78126738106715	CCR1/CXCL8/TNFSF13B/IL18R1/IL1R2/IL1RAP/CXCR2/CXCL1/CSF3R/CXCR4/IL18RAP/IFNGR1/TNFSF14/TNFSF10/IL1RN/CCL3L1	4.38420867201631
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	8/181	90/9376	4.60454266421117	HIF1A/STAT1/TLR2/KRAS/PTEN/MAP2K3/IFNGR1/FOS	4.82065602983067
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	12/181	193/9376	3.22079409154668	CCR1/CXCL8/PLCG2/CXCR2/STAT1/CXCL1/CXCR4/KRAS/PREX1/GNG10/ARRB2/CCL3L1	4.37364686512508
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	11/181	168/9376	3.39173901604841	EIF2AK2/IRF9/FTH1/STAT1/CASP1/TNFAIP3/BIRC2/IFNGR1/TNFSF10/CHMP4B/ZBP1	4.38868926743136
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	13/181	248/9376	2.71538050258421	NAIP/CXCL8/LY96/TLR2/CASP1/BIRC2/MAP2K3/TNFSF10/FOS/ARPC1B/VPS18/SNX18/TXN	3.84102870730259
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	10/181	163/9376	3.17798190014575	CXCL8/STAT1/TLR2/KRAS/E2F3/IFIH1/CREB5/MAP2K3/FOS/YWHAB	3.93546986972356
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	5/181	42/9376	6.16679821099711	ACSL1/FTH1/MAP1LC3B/PCBP1/ACSL4	4.7082694189962
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	12/181	227/9376	2.73838440382603	CCR1/CXCL8/B2M/CXCR2/CXCR4/KRAS/GNG10/E2F3/HLA-C/CREB5/VEGFA/CCL3L1	3.71981199595325
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	6/181	69/9376	4.50444391064136	PLCG2/LCP2/KRAS/GAB2/MAP2K3/ALOX5AP	4.0990938398644
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	7/181	95/9376	3.81692352428031	CXCL8/TNFSF13B/TLR2/CXCL1/VEGFA/FOS/CCL3L1	3.87158262173597
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	6/181	72/9376	4.31675874769797	ISG15/CXCL8/IFIH1/ZNFX1/AZI2/ADAR	3.96364124932532
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	11/181	216/9376	2.63801923470432	CXCL8/LY96/TLR2/CXCL1/CASP1/KRAS/DDIT3/MAP2K3/TNFSF10/FOS/CCL3L1	3.41701743552107
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	9/181	157/9376	2.96949009395784	CXCL8/KRAS/ZFP36L1/E2F3/PTEN/HLA-C/MAP2K3/LIN54/PPP1CB	3.49148980551821
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	8/181	133/9376	3.11585593818801	FCGR3B/PLCG2/LCP2/KRAS/CD48/HLA-C/IFNGR1/TNFSF10	3.44789869837454
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	8/181	137/9376	3.02488204218252	BCL2A1/LMNB1/KRAS/DDIT3/MCL1/BIRC2/TNFSF10/FOS	3.34962807303719
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	6/181	83/9376	3.74465819077415	IFI16/CASP1/PCBP1/ADAR/AIM2/ZBP1	3.52369575492715
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	7/181	110/9376	3.29643395278754	HIF1A/PLCG2/PFKFB3/EDN1/IFNGR1/VEGFA/MKNK1	3.39901603024054
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	10/181	201/9376	2.57716940161073	BCL2A1/NFKBIZ/CXCL8/IL1R2/BCL6/DDIT3/PLAU/BIRC2/DUSP6/PML	3.1711909536292
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	7/181	112/9376	3.23756906077348	LY96/STAT1/TLR2/BIRC2/MAP2K3/IFNGR1/PPIF	3.34222162854154
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	8/181	142/9376	2.91837211111976	FCGR3B/PLCG2/IRF9/LCP2/STAT1/GAB2/IFNGR1/FOS	3.23170081711621
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	4/181	41/9376	5.05376633876836	CXCL8/KRAS/E2F3/VEGFA	3.64957706055637
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	5/181	66/9376	3.92432613427089	IL18R1/STAT1/TLR2/IL18RAP/IFNGR1	3.34481414868957
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	11/181	250/9376	2.27924861878453	SH3GLB1/CXCR2/CXCR4/IST1/HLA-C/ARRB2/VPS26A/ARPC1B/CHMP4B/PML/SH3KBP1	2.87629739336343
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	7/181	122/9376	2.97219454759533	IRS2/PLCG2/STAT1/KRAS/CREB5/MAP2K3/FOS	3.07619583917209
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	10/181	224/9376	2.31254932912391	B2M/IL1R2/ZFP36/KRAS/E2F3/PTEN/HLA-C/CREB5/ETS2/FOS	2.78952781764383
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	5/181	71/9376	3.6479651388997	CXCL8/PLCG2/ADAM17/CXCR2/CXCL1	3.14218902715555
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	13/181	333/9376	2.02226535928193	MX1/ISG15/MX2/OASL/EIF2AK2/IRF9/STAT1/KRAS/PTEN/HLA-C/CREB5/VEGFA/IRF1	2.66488550516149
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	7/181	130/9376	2.78929026774331	KRAS/GNG10/EDN1/CREB5/ARRB2/VEGFA/FOS	2.8822031612665
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	6/181	101/9376	3.07729336469559	CXCL8/PLCG2/STAT1/KRAS/EDN1/VEGFA	2.94476484957524
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	12/181	300/9376	2.07204419889503	LAMTOR3/MAP3K8/IL1RAP/KRAS/DDIT3/ARRB2/MAP2K3/VEGFA/FOS/DUSP6/MKNK1/RASA2	2.64773876371631
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	7/181	133/9376	2.72637394591451	IRS2/GABARAP/KLF2/BCL6/KRAS/PTEN/TNFSF10	2.81321727703441
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	6/181	105/9376	2.96006314127861	PLCG2/IRF9/STAT1/CASP1/KRAS/IRF1	2.83367787809886
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	5/181	77/9376	3.36370811508933	STAT1/RALGDS/KRAS/E2F3/VEGFA	2.9219322630938
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	6/181	106/9376	2.93213801730428	IL1R2/KRAS/PLAU/E2F3/PTEN/CREB5	2.80672763231031
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	5/181	78/9376	3.32058365207536	CXCL8/LY96/CASP1/FOS/IRF1	2.8873459187772
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	5/181	78/9376	3.32058365207536	FCGR3B/STAT1/TLR2/IFNGR1/FOS	2.8873459187772
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	9/181	205/9376	2.27419485244576	GTF2H2/EIF2AK2/IRF9/SP100/KRAS/HLA-C/CREB5/RASA2/YWHAB	2.58793574345943
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	9/181	214/9376	2.17855114369804	PLCG2/B2M/TLR2/CXCR4/KRAS/GNG10/HLA-C/MAP2K3/FOS	2.44686064265804
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	10/181	253/9376	2.04747450483698	NAIP/CXCL8/PLCG2/UBE2D1/MAP1LC3B/CASP1/CD44/RRAGC/ARPC1B/CAST	2.36964857173592
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	5/181	91/9376	2.84621455892174	IFITM1/PLCG2/KRAS/FOS/PIK3AP1	2.48290997003932
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	5/181	94/9376	2.75537792406254	S100A8/CXCL8/CXCL1/TNFAIP3/FOS	2.39973251449489
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	8/181	195/9376	2.12517353732823	FCGR3B/PLCG2/FPR2/TLR2/CASP1/AQP9/PPIF/TLR8	2.22761883036725
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	8/181	200/9376	2.07204419889503	NAIP/CXCL8/CASP1/OCLN/RAB1A/TNFSF10/FOS/ARPC1B	2.1500573549692
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	5/181	98/9376	2.64291351899876	FCGR3B/PLCG2/MARCKS/GAB2/ARPC1B	2.29376866668022
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	9/181	238/9376	1.95886531408143	PLCG2/RALGDS/KRAS/GNG10/SHOC2/GAB2/ETS2/VEGFA/RASA2	2.10217839960722
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	4/181	68/9376	3.04712382190445	BCL2A1/KRAS/DUSP6/PML	2.37694668171119
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	8/181	204/9376	2.03141588126964	HIF1A/PLCG2/TLR2/KRAS/PLAU/CD44/VEGFA/PPP1CB	2.08961334770069
Metabolism	Lipid metabolism	hsa00061	Fatty acid biosynthesis	2/181	18/9376	5.75567833026397	ACSL1/ACSL4	2.83338938563527
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	4/181	71/9376	2.91837211111976	STAT1/KRAS/FOS/IRF1	2.2764226420543
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	4/181	71/9376	2.91837211111976	HIF1A/KRAS/PTEN/SLC7A5	2.2764226420543
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	11/181	323/9376	1.76412431794468	IRS2/PLCG2/MARCKS/KRAS/PLAU/CD44/ZEB2/E2F3/PTEN/MCL1/VEGFA	1.96073129662399
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	5/181	103/9376	2.51461674623183	CXCL8/TLR2/IFNGR1/FOS/CCL3L1	2.16850433945145
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	6/181	138/9376	2.25222195532068	CXCL8/LCP2/CASP1/MAP2K3/FOS/ARPC1B	2.07912661144913
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	4/181	73/9376	2.83841671081511	MX1/MX2/CXCR4/CHMP4B	2.21229448878954
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	5/181	105/9376	2.46671928439884	HIF1A/GABARAP/RABGEF1/MAP1LC3B/KRAS	2.12044699073866
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	6/181	142/9376	2.18877908333982	KLF2/IL1R2/EDN1/VEGFA/FOS/TXN	2.00262415864537
Human Diseases	Cancer: specific types	hsa05214	Glioma	4/181	76/9376	2.72637394591451	PLCG2/KRAS/E2F3/PTEN	2.12006537811924
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	5/181	109/9376	2.37619747579705	HIF1A/IL1RAP/STAT1/IFNGR1/FOS	2.02755891888718
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	5/181	109/9376	2.37619747579705	IRS2/PTEN/PPP1R3B/CREB5/PPP1CB	2.02755891888718
Metabolism	Glycan biosynthesis and metabolism	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	2/181	21/9376	4.93343856879768	DSE/CSGALNACT2	2.53168216528801
NA	NA	hsa03272	Virion - Hepatitis viruses	3/181	48/9376	3.23756906077348	OCLN/IST1/CHMP4B	2.18047874291466
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	6/181	149/9376	2.08595053580036	CXCL8/PLCG2/CXCR2/RALGDS/KRAS/GAB2	1.87465768554541
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	4/181	80/9376	2.59005524861878	PLCG2/KRAS/PTEN/VEGFA	2.00381770499079
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	6/181	158/9376	1.96713056857123	LAMTOR3/KRAS/PTEN/TBC1D7/RRAGC/SLC7A5	1.72006302765263
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	3/181	55/9376	2.82551481667504	UGCG/SAMD8/B4GALT5	1.90495408266764
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	3/181	60/9376	2.59005524861878	PLCG2/KRAS/VEGFA	1.73349326568878
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	5/181	133/9376	1.94740996136751	GNG10/CREB5/ARRB2/PPP1CB/FOS	1.54385443435414
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	4/181	99/9376	2.09297393827781	PLCG2/IL1RAP/MAP2K3/PPP1CB	1.53381395323312
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	4/181	99/9376	2.09297393827781	HIF1A/RALGDS/KRAS/FOS	1.53381395323312
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	5/181	138/9376	1.8768516294339	IRS2/KRAS/PPP1R3B/PPP1CB/MKNK1	1.45588052445677
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	2/181	33/9376	3.13946090741671	STX11/SEC22B	1.72729775974356
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	4/181	103/9376	2.01169339698546	CXCL8/IL1R2/TLR2/CXCL1	1.44845983448644
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	3/181	69/9376	2.25222195532068	CREB5/PPP1CB/FOS	1.46470465331504
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	7/181	227/9376	1.59739090223185	HIF1A/KRAS/ATP5F1E/PTEN/VEGFA/PPIF/FOS	1.27830291131498
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	3/181	70/9376	2.22004735595896	IRS2/ACSL1/ACSL4	1.43745164046384
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	3/181	70/9376	2.22004735595896	HIF1A/KRAS/VEGFA	1.43745164046384
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	5/181	148/9376	1.75003733014783	KRAS/FRAT2/E2F3/PTEN/FOS	1.29035438746227
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	2/181	37/9376	2.80005972823652	KRAS/TPM3	1.53917020918955
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	10/181	362/9376	1.43096975061811	TLR2/CSF3R/KRAS/GNG10/PTEN/MCL1/CREB5/VEGFA/PIK3AP1/YWHAB	1.17325214189429
Human Diseases	Cancer: specific types	hsa05218	Melanoma	3/181	73/9376	2.12881253311133	KRAS/E2F3/PTEN	1.3583785064549
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	3/181	73/9376	2.12881253311133	PLCG2/KRAS/E2F3	1.3583785064549
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	3/181	75/9376	2.07204419889503	PTEN/CD82/SHISA5	1.30775852397175
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	3/181	76/9376	2.04478045943588	ACSL1/GK/ACSL4	1.2830377132529
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	4/181	115/9376	1.80177756425655	KRAS/GNG10/CREB5/FOS	1.21373237480352
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	3/181	77/9376	2.0182248690536	KRAS/E2F3/GAB2	1.25869352352743
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	5/181	157/9376	1.64971671886547	HIF1A/ADAM17/ATP11B/CASP1/VPS18	1.15181046472533
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	5/181	160/9376	1.61878453038674	CD58/OCLN/SELL/HLA-C/NTNG2	1.10758550869577
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	2/181	43/9376	2.40935371964538	ACSL1/ACSL4	1.29954900110465
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	4/181	122/9376	1.69839688434019	MAP3K8/LCP2/KRAS/FOS	1.08934769762829
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	4/181	122/9376	1.69839688434019	HIF1A/PLCG2/STAT1/KRAS	1.08934769762829
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	3/181	82/9376	1.89516237703813	B2M/IFI30/HLA-C	1.14223765186054
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	4/181	125/9376	1.65763535911602	KRAS/PTEN/GAB2/NSMAF	1.03847221397914
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	5/181	168/9376	1.54169955274928	IRF9/STAT1/CSF3R/MCL1/IFNGR1	0.993984292337606
Organismal Systems	Immune system	hsa04611	Platelet activation	4/181	126/9376	1.64447952293256	PLCG2/LCP2/PPP1CB/P2RX1	1.02181573963462
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	5/181	170/9376	1.52356191095223	PLCG2/KRAS/FRAT2/E2F3/PTEN	0.966509391582408
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	3/181	87/9376	1.78624499904744	RALGDS/KRAS/FOS	1.03367044701649
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	3/181	88/9376	1.7659467604219	CFD/PLAU/F5	1.01280975397211
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	6/181	217/9376	1.43228861674772	BCL6/KRAS/CREB5/ARRB2/VEGFA/FOS	0.903917294745598
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	2/181	50/9376	2.07204419889503	TNFSF13B/CXCR4	1.06634821558492
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	2/181	50/9376	2.07204419889503	CXCL8/TLR2	1.06634821558492
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	3/181	90/9376	1.72670349907919	IRS2/KRAS/CREB5	0.971881298428684
Metabolism	Metabolism of cofactors and vitamins	hsa00730	Thiamine metabolism	1/181	15/9376	3.45340699815838	ALPL	1.33414540718742
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	3/181	93/9376	1.67100338620567	STAT1/IFNGR1/FOS	0.912370153570876
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	3/181	93/9376	1.67100338620567	E2F3/PTEN/BIRC2	0.912370153570876
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	6/181	226/9376	1.37525057448785	HCAR3/HCAR2/EDN1/CREB5/PPP1CB/FOS	0.801150479920917
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	4/181	139/9376	1.4906792797806	FKBP5/KRAS/CREB5/FOS	0.817690037203089
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	4/181	140/9376	1.48003157063931	KLF2/MAP1LC3B/KRAS/GNG10	0.802862023177456
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	4/181	142/9376	1.45918605555988	UBE2D1/BIRC2/UBE2R2/PML	0.773547500174532
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	3/181	99/9376	1.56973045370835	KRAS/E2F3/FOS	0.799525486267905
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	3/181	99/9376	1.56973045370835	FCGR3B/CFD/FPR2	0.799525486267905
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	6/181	235/9376	1.32258140355002	ACSL1/KRAS/ATP5F1E/CREB5/MAP2K3/ACSL4	0.702628016339953
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	2/181	57/9376	1.81758263060967	ACSL1/ACSL4	0.868627325125303
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	4/181	144/9376	1.43891958256599	CXCL8/LY96/CXCL1/MAP2K3	0.744676012336755
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	3/181	100/9376	1.55403314917127	IL1R2/CSF3R/CD44	0.781455836716815
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	2/181	59/9376	1.75596966008053	KRAS/PTEN	0.817224509031352
Metabolism	Glycan biosynthesis and metabolism	hsa00541	Biosynthesis of various nucleotide sugars	1/181	20/9376	2.59005524861878	CYB5R4	0.998691066047727
Metabolism	Metabolism of cofactors and vitamins	hsa00770	Pantothenate and CoA biosynthesis	1/181	21/9376	2.46671928439884	VNN2	0.944025688681738
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	2/181	62/9376	1.67100338620567	IRS2/KRAS	0.743706365385509
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	2/181	62/9376	1.67100338620567	ADAM17/DTX3L	0.743706365385509
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	4/181	155/9376	1.33680270896453	FCGR3B/TLR2/HLA-C/SEC22B	0.593200451448491
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	6/181	250/9376	1.24322651933702	LAMTOR3/LITAF/RRAGC/VPS26A/VPS18/TLR8	0.546877122471027
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	2/181	65/9376	1.59388015299618	KRAS/ARRB2	0.67407215218993
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	4/181	157/9376	1.31977337509237	IRS2/CXCL8/DDIT3/FOS	0.566890629527113
Metabolism	Metabolism of terpenoids and polyketides	hsa00900	Terpenoid backbone biosynthesis	1/181	23/9376	2.25222195532068	IDI1	0.8435655271852
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	6/181	254/9376	1.22364814895376	PLCG2/CXCR4/HRH2/VEGFA/PPIF/P2RX1	0.506974588341005
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	2/181	67/9376	1.54630164096644	KRAS/PPP1CB	0.629603958777844
Metabolism	Glycan biosynthesis and metabolism	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	1/181	24/9376	2.15837937384899	HS3ST3B1	0.7971742217917
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	3/181	115/9376	1.35133317319241	CREB5/ARRB2/FOS	0.531848814005519
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	3/181	116/9376	1.33968374928558	PLCG2/CXCR4/OCLN	0.516472652720129
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	5/181	212/9376	1.22172417387679	LCP2/RALGDS/KRAS/MAP2K3/VEGFA	0.45812869470407
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	4/181	166/9376	1.24821939692472	IRS2/CREB5/PPIF/PPP1CB	0.452698446220024
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	3/181	120/9376	1.29502762430939	PLCG2/KRAS/IRAK3	0.456342262289395
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	3/181	122/9376	1.27379766325514	IRS2/PFKFB3/CREB5	0.427064983780355
Metabolism	Glycan biosynthesis and metabolism	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/181	28/9376	1.85003946329913	B3GNT5	0.63198651418772
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	1/181	28/9376	1.85003946329913	ALPL	0.63198651418772
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	2/181	78/9376	1.32823346083015	PLCG2/PTEN	0.408398784799877
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	4/181	181/9376	1.14477580049449	FCGR3B/STAT1/TLR2/IFNGR1	0.275936057175287
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	1/181	32/9376	1.61878453038674	GABARAP	0.491922946002129
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/181	32/9376	1.61878453038674	BIRC2	0.491922946002129
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	8/181	388/9376	1.06806402004898	IRS2/ADAM17/EIF2AK2/KRAS/ATP5F1E/DDIT3/FRAT2/PPIF	0.192110448506336
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	4/181	184/9376	1.12611097766034	PLCG2/CXCR4/KRAS/NTNG2	0.242385064198019
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	2/181	83/9376	1.24821939692472	ACSL1/ACSL4	0.318673428324966
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/181	34/9376	1.52356191095223	NFIL3	0.4290783778309
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	1/181	35/9376	1.48003157063931	PFKFB3	0.399168439221515
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	2/181	86/9376	1.20467685982269	PLCG2/KRAS	0.267521796882305
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	3/181	138/9376	1.12611097766034	CPEB4/PPP1CB/YWHAB	0.209388350472049
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/181	36/9376	1.43891958256599	GYG1	0.370179043232212
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/181	36/9376	1.43891958256599	B4GALT5	0.370179043232212
Human Diseases	Substance dependence	hsa05034	Alcoholism	4/181	191/9376	1.08483989470944	KRAS/GNG10/CREB5/PPP1CB	0.16619818742562
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/181	89/9376	1.16406977466013	GABARAP/GNG10	0.218190039550208
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/181	38/9376	1.36318697295725	NAMPT	0.31473437946528
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/181	38/9376	1.36318697295725	KRAS	0.31473437946528
Human Diseases	Substance dependence	hsa05032	Morphine addiction	2/181	91/9376	1.1384858235687	GNG10/ARRB2	0.186244784164546
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/181	39/9376	1.32823346083015	HLA-C	0.28817780882309
NA	NA	hsa04082	Neuroactive ligand signaling	4/181	199/9376	1.04122824065077	GNG10/HRH2/OGFR/P2RX1	0.0824745649949842
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/181	93/9376	1.11400225747045	KRAS/MAP2K3	0.155010033174193
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	4/181	203/9376	1.02071142802711	PTEN/BIRC2/VEGFA/PPP1CB	0.0418553930924232
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	3/181	150/9376	1.03602209944751	KRAS/FRAT2/E2F3	0.0623960337200867
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	4/181	205/9376	1.01075326775367	ATP5F1E/PTEN/PPIF/PPP1CB	0.0218402749982087
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/181	97/9376	1.06806402004898	GNG10/FOS	0.0945370257542463
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	2/181	98/9376	1.0571654075995	PLCG2/PTEN	0.0798120042554988
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	2/181	99/9376	1.0464869691389	EDN1/TPM3	0.0652370193026902
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	3/181	154/9376	1.0091124345268	CREB5/PPP1CB/TPM3	0.0159967324527045
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	3/181	154/9376	1.0091124345268	KRAS/PPP1CB/FOS	0.0159967324527045
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	1/181	44/9376	1.17729784028127	GTF2H2	0.165383232959006
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/181	44/9376	1.17729784028127	HLA-C	0.165383232959006
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/181	44/9376	1.17729784028127	CREB5	0.165383232959006
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	2/181	101/9376	1.02576445489853	KRAS/EDN1	0.0365236140658312
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/181	45/9376	1.15113566605279	HLA-C	0.14257986044877
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	3/181	157/9376	0.989830031319281	BIRC2/PPP1CB/YWHAB	-0.0180292056711056
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/181	46/9376	1.12611097766034	FTH1	0.12029291396788
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	2/181	103/9376	1.00584669849273	PPP1CB/EIF4A3	0.0083708245564404
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	2/181	104/9376	0.99617509562261	PGS1/SAMD8	-0.00550300109568755
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/181	47/9376	1.10215116962501	IRS2	0.098497177326059
NA	NA	hsa04382	Cornified envelope formation	4/181	217/9376	0.95485907783181	S100A8/UGCG/OCLN/S100A12	-0.094389855915186
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/181	49/9376	1.0571654075995	CREB5	0.0562871701446251
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	2/181	110/9376	0.941838272225012	KRAS/CPEB4	-0.0860867976689241
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/181	51/9376	1.01570794063482	PLCG2	0.0157807986244529
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	3/181	170/9376	0.914137146571336	OCLN/RAB8B/ARPC1B	-0.158505140444489
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/181	54/9376	0.959279721710661	HLA-C	-0.0421019418271624
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/181	115/9376	0.900888782128273	KRAS/GNG10	-0.150034746792477
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	4/181	232/9376	0.893122499523719	CXCR4/KRAS/PPP1CB/ARPC1B	-0.231265702983674
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/181	56/9376	0.925019731649566	ARRB2	-0.0789554488133695
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/181	59/9376	0.877984830040266	CMPK2	-0.131901837640016
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/181	59/9376	0.877984830040266	IRS2	-0.131901837640016
NA	NA	hsa04517	IgSF CAM signaling	5/181	299/9376	0.866239213584878	PLCG2/LCP2/IL1RAP/CD48/ARPC1B	-0.329793657168743
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/181	60/9376	0.863351749539595	KRAS	-0.148975214632971
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/181	61/9376	0.849198442170093	FTH1	-0.165778564499951
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/181	63/9376	0.822239761466281	GTF2H2	-0.198613679171919
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	8/181	480/9376	0.863351749539595	MAP1LC3B/KRAS/ATP5F1E/DDIT3/FRAT2/RAB1A/MAP2K3/PPIF	-0.43119763093573
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/181	65/9376	0.796940076498088	GK	-0.230479228793723
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/181	65/9376	0.796940076498088	CREB5	-0.230479228793723
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	6/181	368/9376	0.844583233245256	MAP1LC3B/CASP1/ATP5F1E/DDIT3/RAB1A/MAP2K3	-0.426733412994215
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	2/181	134/9376	0.773150820483219	EDN1/PPP1CB	-0.371069867152603
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/181	69/9376	0.750740651773561	EDN1	-0.291554804384534
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/181	70/9376	0.740015785319653	HLA-C	-0.306311664101946
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	4/181	268/9376	0.773150820483219	ATP5F1E/DDIT3/PPIF/TXN	-0.528618256190928
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/181	75/9376	0.690681399631676	BIRC2	-0.377329625655012
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/181	75/9376	0.690681399631676	CREB5	-0.377329625655012
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	2/181	144/9376	0.719459791282996	KRAS/SKIL	-0.475967744948108
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/181	76/9376	0.681593486478627	HRH2	-0.3910176164798
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	4/181	275/9376	0.75347061778001	ATP5F1E/DDIT3/CREB5/PPIF	-0.582156211935087
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/181	78/9376	0.664116730415073	TENT4B	-0.417916926525899
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/181	78/9376	0.664116730415073	ARPC1B	-0.417916926525899
NA	NA	hsa04519	Cadherin signaling	6/181	404/9376	0.769323341173896	KRAS/SHOC2/MAP2K3/PPP1CB/ARPC1B/YWHAB	-0.664964960516593
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	2/181	154/9376	0.672741623017866	CMPK2/ALPL	-0.574496824541613
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/181	83/9376	0.624109698462358	UBE2D1	-0.482582153325579
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/181	155/9376	0.668401354482267	E2F3/CREB5	-0.584034691483259
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/181	85/9376	0.60942476438089	CMPK2	-0.50749526560609
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	2/181	158/9376	0.655710189523743	E2F3/YWHAB	-0.612327014616668
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/181	86/9376	0.602338429911345	CREB5	-0.51976143210969
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	1/181	87/9376	0.595414999682479	TPM3	-0.531904887968829
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/181	89/9376	0.582034887330064	CD44	-0.55583561721209
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/181	89/9376	0.582034887330064	KRAS	-0.55583561721209
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/181	90/9376	0.575567833026397	AQP9	-0.56762859413211
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	5/181	370/9376	0.700014932059131	FPR2/EDN1/HRH2/OGFR/P2RX1	-0.826006732990857
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/181	98/9376	0.528582703799752	CREB5	-0.658173549886076
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	2/181	174/9376	0.595414999682479	UBE2D1/DDIT3	-0.75577469400657
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/181	105/9376	0.493343856879769	TPM3	-0.732476558702153
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/181	107/9376	0.484122476377343	CREB5	-0.752958626055919
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	1/181	108/9376	0.47963986085533	EIF4A3	-0.763083292991678
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/181	110/9376	0.470919136112506	SKIL	-0.783107363250816
Cellular Processes	Cell motility	hsa04814	Motor proteins	2/181	194/9376	0.534032010024492	KIF1B/TPM3	-0.920104941500857
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/181	116/9376	0.446561249761859	GNG10	-0.841476756114399
NA	NA	hsa04081	Hormone signaling	2/181	219/9376	0.473069451802518	IRS2/GNG10	-1.10700067630401
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	1/181	138/9376	0.37537032588678	ATP5F1E	-1.03710382351267
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/181	143/9376	0.362245489317312	FCGR3B	-1.0781996803817
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	3/181	308/9376	0.5045562172634	ATP5F1E/CREB5/PPIF	-1.24040367492092
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/181	144/9376	0.359729895641498	PPIF	-1.08628962359054
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	2/181	233/9376	0.444644677874469	LMNB1/TPM3	-1.20435244227235
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	1/181	149/9376	0.347658422633394	GNG10	-1.12612601706561
Genetic Information Processing	Transcription	hsa03040	Spliceosome	2/181	243/9376	0.426346542982516	PCBP1/EIF4A3	-1.27114496613193
NA	NA	hsa04518	Integrin signaling	1/181	154/9376	0.336370811508933	VEGFA	-1.16499038153593
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/181	178/9376	0.291017443665032	FRAT2	-1.33982447648009
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	1/181	183/9376	0.283066147390031	NOP10	-1.37412126745903
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	2/181	449/9376	0.230739888518377	OR11G2/ARRB2	-2.34364957201651