ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003712 transcription coregulator activity 50/788 495/18639 0.101010101010101 2.38924780802953 1.12202086909813e-08 1.01430686566471e-05 GO:0140297 DNA-binding transcription factor binding 46/788 488/18639 0.0942622950819672 2.22963822085379 3.33438367191008e-07 0.000150714141970336 GO:0043021 ribonucleoprotein complex binding 21/788 177/18639 0.11864406779661 2.80635378129571 1.95953004299665e-05 0.00557740005693912 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 32/788 349/18639 0.0916905444126074 2.16880717932308 3.53633735071527e-05 0.00557740005693912 GO:0001098 basal transcription machinery binding 11/788 60/18639 0.183333333333333 4.3364847715736 3.70181419708348e-05 0.00557740005693912 GO:0001099 basal RNA polymerase II transcription machinery binding 11/788 60/18639 0.183333333333333 4.3364847715736 3.70181419708348e-05 0.00557740005693912 GO:0003743 translation initiation factor activity 10/788 51/18639 0.196078431372549 4.63795162735145 4.55761541311074e-05 0.00588583476207444 GO:0003714 transcription corepressor activity 22/788 204/18639 0.107843137254902 2.5508733950433 5.52078357579757e-05 0.00623848544065125 GO:0140296 general transcription initiation factor binding 10/788 53/18639 0.188679245283019 4.46293458480988 6.44372329916287e-05 0.00647236206938137 GO:0017069 snRNA binding 10/788 54/18639 0.185185185185185 4.38028764805415 7.61213239160033e-05 0.0068813676820067 GO:0003713 transcription coactivator activity 25/788 256/18639 0.09765625 2.30991731440355 9.13530820429529e-05 0.00750756237880268 GO:0019003 GDP binding 11/788 75/18639 0.146666666666667 3.46918781725888 0.000297554599671969 0.0206914890848816 GO:0044183 protein folding chaperone 11/788 75/18639 0.146666666666667 3.46918781725888 0.000297554599671969 0.0206914890848816 GO:0001091 RNA polymerase II general transcription initiation factor binding 6/788 24/18639 0.25 5.9133883248731 0.000391930128122937 0.0253074882730811 GO:0001094 TFIID-class transcription factor complex binding 4/788 10/18639 0.4 9.46142131979695 0.000542715122505061 0.0327076313829717 GO:0050681 nuclear androgen receptor binding 6/788 26/18639 0.230769230769231 5.45851229988286 0.000623713126521751 0.0352397916484789 GO:0016922 nuclear receptor binding 15/788 137/18639 0.109489051094891 2.58980510578384 0.000692472587976121 0.0362741699736563 GO:0008135 translation factor activity, RNA binding 11/788 83/18639 0.132530120481928 3.13480826860742 0.000722273295935634 0.0362741699736563 GO:0180051 translation factor activity 11/788 84/18639 0.130952380952381 3.09748912255257 0.000799997064788657 0.0380630182404708 GO:0097677 STAT family protein binding 4/788 12/18639 0.333333333333333 7.88451776649746 0.00119537177702843 0.0540308043216848 GO:0140662 ATP-dependent protein folding chaperone 7/788 40/18639 0.175 4.13937182741117 0.00129375448813679 0.05569305034646 GO:0061650 ubiquitin-like protein conjugating enzyme activity 7/788 41/18639 0.170731707317073 4.03841153893772 0.00150407834041433 0.0618039463515708 GO:0019104 DNA N-glycosylase activity 4/788 13/18639 0.307692307692308 7.27801639984381 0.0016692063305063 0.0632852986194202 GO:0140035 ubiquitin-like protein reader activity 5/788 22/18639 0.227272727272727 5.37580756806645 0.00192659791963248 0.0632852986194202 GO:0042393 histone binding 21/788 247/18639 0.0850202429149798 2.01103084732526 0.00192995754195454 0.0632852986194202 GO:0031369 translation initiation factor binding 6/788 32/18639 0.1875 4.43504124365482 0.00197839591366875 0.0632852986194202 GO:0051059 NF-kappaB binding 6/788 32/18639 0.1875 4.43504124365482 0.00197839591366875 0.0632852986194202 GO:0048156 tau protein binding 7/788 43/18639 0.162790697674419 3.85057844410341 0.0020039185953201 0.0632852986194202 GO:0016755 aminoacyltransferase activity 35/788 496/18639 0.0705645161290323 1.66910154331095 0.00221237185943957 0.0632852986194202 GO:0008474 palmitoyl-(protein) hydrolase activity 4/788 14/18639 0.285714285714286 6.75815808556925 0.00225926339772942 0.0632852986194202 GO:0098599 palmitoyl hydrolase activity 4/788 14/18639 0.285714285714286 6.75815808556925 0.00225926339772942 0.0632852986194202 GO:0140097 catalytic activity, acting on DNA 26/788 336/18639 0.0773809523809524 1.83033448150834 0.00230692000787137 0.0632852986194202 GO:0019787 ubiquitin-like protein transferase activity 34/788 479/18639 0.0709812108559499 1.67895785424372 0.00231019342305406 0.0632852986194202 GO:0043022 ribosome binding 12/788 112/18639 0.107142857142857 2.53430928208847 0.00275744747383341 0.0727348832850804 GO:0051117 ATPase binding 10/788 84/18639 0.119047619047619 2.81589920232052 0.00281606295904626 0.0727348832850804 GO:0003735 structural constituent of ribosome 16/788 175/18639 0.0914285714285714 2.16261058738216 0.00312992680729969 0.0770445179433177 GO:0061631 ubiquitin conjugating enzyme activity 6/788 35/18639 0.171428571428571 4.05489485134155 0.00318258740101259 0.0770445179433177 GO:0070063 RNA polymerase binding 8/788 59/18639 0.135593220338983 3.20726146433795 0.00323859699319256 0.0770445179433177 GO:0016887 ATP hydrolysis activity 30/788 417/18639 0.0719424460431655 1.70169448197787 0.00334180378804927 0.0774612980614497 GO:0017025 TBP-class protein binding 5/788 25/18639 0.2 4.73071065989848 0.0035000503617356 0.0791011381752247 GO:0017070 U6 snRNA binding 4/788 16/18639 0.25 5.9133883248731 0.00383999229138343 0.0820798956070792 GO:0003684 damaged DNA binding 9/788 74/18639 0.121621621621622 2.87678350939772 0.003896426676096 0.0820798956070792 GO:0016651 oxidoreductase activity, acting on NAD(P)H 10/788 88/18639 0.113636363636364 2.68790378403323 0.00396039450167363 0.0820798956070792 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 8/788 61/18639 0.131147540983607 3.1021053507531 0.00399503916671624 0.0820798956070792 GO:0004659 prenyltransferase activity 4/788 17/18639 0.235294117647059 5.56554195282174 0.00485549636838823 0.095565901521469 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 6/788 38/18639 0.157894736842105 3.73477157360406 0.00486286667034024 0.095565901521469 GO:0044389 ubiquitin-like protein ligase binding 24/788 322/18639 0.0745341614906832 1.76299776145285 0.00531300151297255 0.102190497185685 GO:0004532 RNA exonuclease activity 6/788 40/18639 0.15 3.54803299492386 0.00629607332254856 0.118576047574665 GO:0008137 NADH dehydrogenase (ubiquinone) activity 6/788 41/18639 0.146341463414634 3.46149560480376 0.0071175581766287 0.12854970027871 GO:0008140 cAMP response element binding protein binding 3/788 10/18639 0.3 7.09606598984772 0.00722698894584064 0.12854970027871 GO:0140036 ubiquitin-modified protein reader activity 4/788 19/18639 0.210526315789474 4.97969543147208 0.00739445178594352 0.12854970027871 GO:1990380 K48-linked deubiquitinase activity 4/788 19/18639 0.210526315789474 4.97969543147208 0.00739445178594352 0.12854970027871 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 8/788 68/18639 0.117647058823529 2.78277097641087 0.0077522205711862 0.132226554648157 GO:0043175 RNA polymerase core enzyme binding 6/788 42/18639 0.142857142857143 3.37907904278463 0.00801379932049718 0.134156936772768 GO:0000339 RNA cap binding 4/788 20/18639 0.2 4.73071065989848 0.00893890180327514 0.146923040548377 GO:0031625 ubiquitin protein ligase binding 22/788 302/18639 0.0728476821192053 1.7231065317511 0.0095490845437954 0.152696176783667 GO:0070990 snRNP binding 3/788 11/18639 0.272727272727273 6.45096908167974 0.00962796689897014 0.152696176783667 GO:0003954 NADH dehydrogenase activity 6/788 44/18639 0.136363636363636 3.22548454083987 0.0100448080347862 0.153906889210962 GO:0016790 thiolester hydrolase activity 6/788 44/18639 0.136363636363636 3.22548454083987 0.0100448080347862 0.153906889210962 GO:0005525 GTP binding 26/788 378/18639 0.0687830687830688 1.62696398356297 0.0104970846149398 0.158156074865093 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 7/788 58/18639 0.120689655172414 2.85473919131805 0.0108472873196148 0.160753241589046 GO:0019001 guanyl nucleotide binding 27/788 400/18639 0.0675 1.59661484771574 0.0116414223032378 0.167045170827412 GO:0032561 guanyl ribonucleotide binding 27/788 400/18639 0.0675 1.59661484771574 0.0116414223032378 0.167045170827412 GO:0000340 RNA 7-methylguanosine cap binding 3/788 12/18639 0.25 5.9133883248731 0.0124388319396174 0.170335969304589 GO:0004407 histone deacetylase activity 4/788 22/18639 0.181818181818182 4.30064605445316 0.0126244579019994 0.170335969304589 GO:0033558 protein lysine deacetylase activity 4/788 22/18639 0.181818181818182 4.30064605445316 0.0126244579019994 0.170335969304589 GO:0050321 tau-protein kinase activity 4/788 22/18639 0.181818181818182 4.30064605445316 0.0126244579019994 0.170335969304589 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 7/788 60/18639 0.116666666666667 2.75958121827411 0.0129638056911343 0.17234235801155 GO:0044013 histone H2B acetyltransferase activity 4/788 23/18639 0.173913043478261 4.11366144338998 0.0147817949941936 0.191818694454135 GO:0000175 3'-5'-RNA exonuclease activity 5/788 35/18639 0.142857142857143 3.37907904278463 0.0151188704336603 0.191818694454135 GO:0140693 molecular condensate scaffold activity 6/788 48/18639 0.125 2.95669416243655 0.0151570771158413 0.191818694454135 GO:0140030 modification-dependent protein binding 14/788 173/18639 0.0809248554913295 1.91416038261788 0.0152775951335152 0.191818694454135 GO:0046974 histone H3K9 methyltransferase activity 3/788 13/18639 0.230769230769231 5.45851229988286 0.0156697196223508 0.194046938885001 GO:0004842 ubiquitin-protein transferase activity 29/788 449/18639 0.0645879732739421 1.52773506834138 0.01598050113697 0.195221257132715 GO:0000993 RNA polymerase II complex binding 5/788 36/18639 0.138888888888889 3.28521573604061 0.0169630497978346 0.201771013384769 GO:0005484 SNAP receptor activity 5/788 36/18639 0.138888888888889 3.28521573604061 0.0169630497978346 0.201771013384769 GO:0019783 ubiquitin-like protein peptidase activity 11/788 127/18639 0.0866141732283465 2.04873296294816 0.0188551905896535 0.216419141524966 GO:0140104 molecular carrier activity 18/788 249/18639 0.072289156626506 1.70989541924041 0.0191717322191086 0.216419141524966 GO:0008494 translation activator activity 3/788 14/18639 0.214285714285714 5.06861856417694 0.0193271167745202 0.216419141524966 GO:0019843 rRNA binding 7/788 65/18639 0.107692307692308 2.54730573994533 0.0195251381475797 0.216419141524966 GO:0160215 deacylase activity 7/788 65/18639 0.107692307692308 2.54730573994533 0.0195251381475797 0.216419141524966 GO:0031490 chromatin DNA binding 11/788 128/18639 0.0859375 2.03272723667513 0.0198703415338187 0.216419141524966 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 11/788 128/18639 0.0859375 2.03272723667513 0.0198703415338187 0.216419141524966 GO:0030971 receptor tyrosine kinase binding 8/788 81/18639 0.0987654320987654 2.33615341229554 0.0209828736303736 0.224244180104746 GO:0042162 telomeric DNA binding 5/788 38/18639 0.131578947368421 3.11230964467005 0.0210849063151587 0.224244180104746 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 5/788 39/18639 0.128205128205128 3.03250683326825 0.023370079964831 0.245657584746596 GO:0030145 manganese ion binding 7/788 68/18639 0.102941176470588 2.43492460435951 0.0244188852008191 0.25360367705291 GO:0009055 electron transfer activity 10/788 116/18639 0.0862068965517241 2.03909942237003 0.025176144179868 0.25360367705291 GO:1901981 phosphatidylinositol phosphate binding 14/788 185/18639 0.0756756756756757 1.78999862806969 0.0256512435345187 0.25360367705291 GO:0001671 ATPase activator activity 4/788 27/18639 0.148148148148148 3.50423011844332 0.025657947220015 0.25360367705291 GO:0061791 GTPase motor activity 5/788 40/18639 0.125 2.95669416243655 0.0258092237708713 0.25360367705291 GO:1990606 membrane scission GTPase motor activity 5/788 40/18639 0.125 2.95669416243655 0.0258092237708713 0.25360367705291 GO:1990782 protein tyrosine kinase binding 10/788 117/18639 0.0854700854700855 2.02167122217884 0.0265287483768086 0.257870844436935 GO:0061659 ubiquitin-like protein ligase activity 24/788 372/18639 0.0645161290322581 1.52603569674144 0.0269148341667816 0.258840532837985 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 3/788 16/18639 0.1875 4.43504124365482 0.0279313711780847 0.261818842609056 GO:0030275 LRR domain binding 3/788 16/18639 0.1875 4.43504124365482 0.0279313711780847 0.261818842609056 GO:0016877 ligase activity, forming carbon-sulfur bonds 5/788 41/18639 0.121951219512195 2.8845796706698 0.0284052884367384 0.261818842609056 GO:0140318 protein transporter activity 5/788 41/18639 0.121951219512195 2.8845796706698 0.0284052884367384 0.261818842609056 GO:0140597 protein carrier chaperone 14/788 188/18639 0.074468085106383 1.76143482017496 0.0289110047495602 0.261818842609056 GO:0051537 2 iron, 2 sulfur cluster binding 4/788 28/18639 0.142857142857143 3.37907904278463 0.0289622613505593 0.261818842609056 GO:0032182 ubiquitin-like protein binding 10/788 120/18639 0.0833333333333333 1.97112944162437 0.0308971591964704 0.276171070068213 GO:0016859 cis-trans isomerase activity 5/788 42/18639 0.119047619047619 2.81589920232052 0.0311608950740682 0.276171070068213 GO:0003697 single-stranded DNA binding 10/788 121/18639 0.0826446280991736 1.95483911566053 0.032459764580232 0.284889584276987 GO:0008408 3'-5' exonuclease activity 6/788 58/18639 0.103448275862069 2.44691930684404 0.0351842813361101 0.305832599306188 GO:0140658 ATP-dependent chromatin remodeler activity 12/788 158/18639 0.0759493670886076 1.79647240249309 0.0361112054726737 0.309531167644975 GO:0031624 ubiquitin conjugating enzyme binding 4/788 30/18639 0.133333333333333 3.15380710659898 0.0362945838167781 0.309531167644975 GO:0031593 polyubiquitin modification-dependent protein binding 6/788 59/18639 0.101694915254237 2.40544609825346 0.0378234602691423 0.319555215731819 GO:0003725 double-stranded RNA binding 7/788 75/18639 0.0933333333333333 2.20766497461929 0.0389533357758261 0.321837037512925 GO:0003689 DNA clamp loader activity 12/788 160/18639 0.075 1.77401649746193 0.0391833132302615 0.321837037512925 GO:0004843 cysteine-type deubiquitinase activity 9/788 108/18639 0.0833333333333333 1.97112944162437 0.0393502471595792 0.321837037512925 GO:0016878 acid-thiol ligase activity 4/788 31/18639 0.129032258064516 3.05207139348289 0.0403255028778045 0.321837037512925 GO:0070273 phosphatidylinositol-4-phosphate binding 4/788 31/18639 0.129032258064516 3.05207139348289 0.0403255028778045 0.321837037512925 GO:0046915 transition metal ion transmembrane transporter activity 5/788 45/18639 0.111111111111111 2.62817258883249 0.0404061773444455 0.321837037512925 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 6/788 60/18639 0.1 2.36535532994924 0.0405856441111432 0.321837037512925 GO:0016853 isomerase activity 13/788 180/18639 0.0722222222222222 1.70831218274112 0.0423657183231839 0.333031385775289 GO:0140713 histone chaperone activity 12/788 164/18639 0.0731707317073171 1.73074780240188 0.0458688445486557 0.340415209532093 GO:0051020 GTPase binding 20/788 315/18639 0.0634920634920635 1.50181290790428 0.0466852386593052 0.340415209532093 GO:0015095 magnesium ion transmembrane transporter activity 3/788 20/18639 0.15 3.54803299492386 0.0502206793365973 0.340415209532093 GO:0043024 ribosomal small subunit binding 3/788 20/18639 0.15 3.54803299492386 0.0502206793365973 0.340415209532093 GO:0016407 acetyltransferase activity 8/788 96/18639 0.0833333333333333 1.97112944162437 0.0503136417921879 0.340415209532093 GO:0032266 phosphatidylinositol-3-phosphate binding 5/788 48/18639 0.104166666666667 2.46391180203046 0.0511496775210073 0.340415209532093 GO:0008234 cysteine-type peptidase activity 13/788 187/18639 0.0695187165775401 1.64436466787915 0.0544254890933177 0.340415209532093 GO:0101005 deubiquitinase activity 9/788 115/18639 0.0782608695652174 1.85114764952549 0.0548429226178815 0.340415209532093 GO:0060590 ATPase regulator activity 5/788 49/18639 0.102040816326531 2.4136278877033 0.0550674837176469 0.340415209532093 GO:0008170 N-methyltransferase activity 8/788 98/18639 0.0816326530612245 1.93090231016264 0.0555763757657447 0.340415209532093 GO:0000510 H3-H4 histone complex chaperone activity 11/788 151/18639 0.0728476821192053 1.7231065317511 0.0557524959197403 0.340415209532093 GO:0140584 chromatin extrusion motor activity 11/788 151/18639 0.0728476821192053 1.7231065317511 0.0557524959197403 0.340415209532093 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 11/788 151/18639 0.0728476821192053 1.7231065317511 0.0557524959197403 0.340415209532093 GO:0140849 ATP-dependent H2AZ histone chaperone activity 11/788 151/18639 0.0728476821192053 1.7231065317511 0.0557524959197403 0.340415209532093 GO:0031267 small GTPase binding 18/788 283/18639 0.0636042402826855 1.50446628760022 0.0561299904549205 0.340415209532093 GO:0005123 death receptor binding 3/788 21/18639 0.142857142857143 3.37907904278463 0.0568108938175869 0.340415209532093 GO:0015616 DNA translocase activity 11/788 152/18639 0.0723684210526316 1.71177030456853 0.057923522747729 0.340415209532093 GO:0140674 ATP-dependent histone chaperone activity 11/788 152/18639 0.0723684210526316 1.71177030456853 0.057923522747729 0.340415209532093 GO:0010485 histone H4 acetyltransferase activity 4/788 35/18639 0.114285714285714 2.7032632342277 0.0588804940192459 0.340415209532093 GO:0034061 DNA polymerase activity 4/788 35/18639 0.114285714285714 2.7032632342277 0.0588804940192459 0.340415209532093 GO:0140566 histone reader activity 4/788 35/18639 0.114285714285714 2.7032632342277 0.0588804940192459 0.340415209532093 GO:0061775 cohesin loader activity 11/788 153/18639 0.0718954248366013 1.7005822633622 0.0601497656800672 0.340415209532093 GO:0019207 kinase regulator activity 18/788 287/18639 0.0627177700348432 1.48349811634447 0.0625107935626596 0.340415209532093 GO:0022853 active monoatomic ion transmembrane transporter activity 9/788 118/18639 0.076271186440678 1.8040845736901 0.0625457071982773 0.340415209532093 GO:0008094 ATP-dependent activity, acting on DNA 14/788 210/18639 0.0666666666666667 1.57690355329949 0.0625731431698323 0.340415209532093 GO:0005048 signal sequence binding 5/788 51/18639 0.0980392156862745 2.31897581367572 0.0634084718558978 0.340415209532093 GO:0008093 cytoskeletal anchor activity 3/788 22/18639 0.136363636363636 3.22548454083987 0.0637876994884692 0.340415209532093 GO:0032931 histone H3K56 acetyltransferase activity 3/788 22/18639 0.136363636363636 3.22548454083987 0.0637876994884692 0.340415209532093 GO:0043992 histone H3K9 acetyltransferase activity 3/788 22/18639 0.136363636363636 3.22548454083987 0.0637876994884692 0.340415209532093 GO:0043993 histone H3K18 acetyltransferase activity 3/788 22/18639 0.136363636363636 3.22548454083987 0.0637876994884692 0.340415209532093 GO:0043994 histone H3K23 acetyltransferase activity 3/788 22/18639 0.136363636363636 3.22548454083987 0.0637876994884692 0.340415209532093 GO:0043999 histone H2AK5 acetyltransferase activity 3/788 22/18639 0.136363636363636 3.22548454083987 0.0637876994884692 0.340415209532093 GO:0044012 histone H2AK9 acetyltransferase activity 3/788 22/18639 0.136363636363636 3.22548454083987 0.0637876994884692 0.340415209532093 GO:0044014 histone H2BK5 acetyltransferase activity 3/788 22/18639 0.136363636363636 3.22548454083987 0.0637876994884692 0.340415209532093 GO:0044015 histone H2BK12 acetyltransferase activity 3/788 22/18639 0.136363636363636 3.22548454083987 0.0637876994884692 0.340415209532093 GO:0044016 histone H3K4 acetyltransferase activity 3/788 22/18639 0.136363636363636 3.22548454083987 0.0637876994884692 0.340415209532093 GO:0044017 histone H3K27 acetyltransferase activity 3/788 22/18639 0.136363636363636 3.22548454083987 0.0637876994884692 0.340415209532093 GO:0044018 histone H3K36 acetyltransferase activity 3/788 22/18639 0.136363636363636 3.22548454083987 0.0637876994884692 0.340415209532093 GO:0046972 histone H4K16 acetyltransferase activity 3/788 22/18639 0.136363636363636 3.22548454083987 0.0637876994884692 0.340415209532093 GO:0140908 histone H3K122 acetyltransferase activity 3/788 22/18639 0.136363636363636 3.22548454083987 0.0637876994884692 0.340415209532093 GO:0042277 peptide binding 16/788 249/18639 0.0642570281124498 1.51990703932481 0.0639688693477456 0.340415209532093 GO:0044390 ubiquitin-like protein conjugating enzyme binding 4/788 36/18639 0.111111111111111 2.62817258883249 0.0641201745469223 0.340415209532093 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 4/788 36/18639 0.111111111111111 2.62817258883249 0.0641201745469223 0.340415209532093 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 4/788 36/18639 0.111111111111111 2.62817258883249 0.0641201745469223 0.340415209532093 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 4/788 36/18639 0.111111111111111 2.62817258883249 0.0641201745469223 0.340415209532093 GO:0005522 profilin binding 2/788 10/18639 0.2 4.73071065989848 0.0641326101784742 0.340415209532093 GO:0008190 eukaryotic initiation factor 4E binding 2/788 10/18639 0.2 4.73071065989848 0.0641326101784742 0.340415209532093 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/788 10/18639 0.2 4.73071065989848 0.0641326101784742 0.340415209532093 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 2/788 10/18639 0.2 4.73071065989848 0.0641326101784742 0.340415209532093 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 2/788 10/18639 0.2 4.73071065989848 0.0641326101784742 0.340415209532093 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/788 10/18639 0.2 4.73071065989848 0.0641326101784742 0.340415209532093 GO:0098505 G-rich strand telomeric DNA binding 2/788 10/18639 0.2 4.73071065989848 0.0641326101784742 0.340415209532093 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 2/788 10/18639 0.2 4.73071065989848 0.0641326101784742 0.340415209532093 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 2/788 10/18639 0.2 4.73071065989848 0.0641326101784742 0.340415209532093 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 2/788 10/18639 0.2 4.73071065989848 0.0641326101784742 0.340415209532093 GO:0004527 exonuclease activity 7/788 84/18639 0.0833333333333333 1.97112944162437 0.0646517895821825 0.340415209532093 GO:0004386 helicase activity 11/788 155/18639 0.0709677419354839 1.67863926641559 0.0647692655304424 0.340415209532093 GO:0019213 deacetylase activity 4/788 37/18639 0.108108108108108 2.55714089724242 0.0695952954114554 0.353347697730768 GO:0004540 RNA nuclease activity 9/788 121/18639 0.0743801652892562 1.75935520409448 0.070904141075506 0.353347697730768 GO:0051082 unfolded protein binding 9/788 121/18639 0.0743801652892562 1.75935520409448 0.070904141075506 0.353347697730768 GO:0002039 p53 binding 6/788 69/18639 0.0869565217391304 2.05683072169499 0.0711320877128469 0.353347697730768 GO:0008080 N-acetyltransferase activity 6/788 69/18639 0.0869565217391304 2.05683072169499 0.0711320877128469 0.353347697730768 GO:0003887 DNA-directed DNA polymerase activity 3/788 23/18639 0.130434782608696 3.08524608254249 0.0711385851626104 0.353347697730768 GO:0004602 glutathione peroxidase activity 3/788 23/18639 0.130434782608696 3.08524608254249 0.0711385851626104 0.353347697730768 GO:0005158 insulin receptor binding 3/788 23/18639 0.130434782608696 3.08524608254249 0.0711385851626104 0.353347697730768 GO:0140102 catalytic activity, acting on a rRNA 3/788 23/18639 0.130434782608696 3.08524608254249 0.0711385851626104 0.353347697730768 GO:0140103 catalytic activity, acting on a glycoprotein 3/788 23/18639 0.130434782608696 3.08524608254249 0.0711385851626104 0.353347697730768 GO:0034212 protein N-acetyltransferase activity 5/788 53/18639 0.0943396226415094 2.23146729240494 0.0724196494930552 0.357745153779901 GO:0043531 ADP binding 4/788 38/18639 0.105263157894737 2.48984771573604 0.0753024000110197 0.362764509626555 GO:0019887 protein kinase regulator activity 16/788 255/18639 0.0627450980392157 1.48414452075246 0.0755000935941105 0.362764509626555 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 2/788 11/18639 0.181818181818182 4.30064605445316 0.0762447531294751 0.362764509626555 GO:0043522 leucine zipper domain binding 2/788 11/18639 0.181818181818182 4.30064605445316 0.0762447531294751 0.362764509626555 GO:0047676 arachidonate-CoA ligase activity 2/788 11/18639 0.181818181818182 4.30064605445316 0.0762447531294751 0.362764509626555 GO:0140537 transcription regulator activator activity 2/788 11/18639 0.181818181818182 4.30064605445316 0.0762447531294751 0.362764509626555 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/788 11/18639 0.181818181818182 4.30064605445316 0.0762447531294751 0.362764509626555 GO:0004622 lysophospholipase activity 3/788 24/18639 0.125 2.95669416243655 0.0788500616612679 0.367425029596836 GO:0043998 histone H2A acetyltransferase activity 3/788 24/18639 0.125 2.95669416243655 0.0788500616612679 0.367425029596836 GO:0048027 mRNA 5'-UTR binding 3/788 24/18639 0.125 2.95669416243655 0.0788500616612679 0.367425029596836 GO:0070840 dynein complex binding 3/788 24/18639 0.125 2.95669416243655 0.0788500616612679 0.367425029596836 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 4/788 39/18639 0.102564102564103 2.4260054666146 0.0812375223020128 0.376608821338562 GO:0042974 nuclear retinoic acid receptor binding 3/788 25/18639 0.12 2.83842639593909 0.0869078230543415 0.386833497020057 GO:0047617 fatty acyl-CoA hydrolase activity 3/788 25/18639 0.12 2.83842639593909 0.0869078230543415 0.386833497020057 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 3/788 25/18639 0.12 2.83842639593909 0.0869078230543415 0.386833497020057 GO:0015036 disulfide oxidoreductase activity 4/788 40/18639 0.1 2.36535532994924 0.0873962221388063 0.386833497020057 GO:0030331 nuclear estrogen receptor binding 4/788 40/18639 0.1 2.36535532994924 0.0873962221388063 0.386833497020057 GO:0032451 demethylase activity 4/788 40/18639 0.1 2.36535532994924 0.0873962221388063 0.386833497020057 GO:0043539 protein serine/threonine kinase activator activity 6/788 73/18639 0.0821917808219178 1.94412766845143 0.088025610927859 0.386833497020057 GO:0008603 cAMP-dependent protein kinase regulator activity 2/788 12/18639 0.166666666666667 3.94225888324873 0.0890059373674467 0.386833497020057 GO:0034452 dynactin binding 2/788 12/18639 0.166666666666667 3.94225888324873 0.0890059373674467 0.386833497020057 GO:0043047 single-stranded telomeric DNA binding 2/788 12/18639 0.166666666666667 3.94225888324873 0.0890059373674467 0.386833497020057 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/788 12/18639 0.166666666666667 3.94225888324873 0.0890059373674467 0.386833497020057 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/788 12/18639 0.166666666666667 3.94225888324873 0.0890059373674467 0.386833497020057 GO:1990817 poly(A) RNA polymerase activity 2/788 12/18639 0.166666666666667 3.94225888324873 0.0890059373674467 0.386833497020057 GO:0015399 primary active transmembrane transporter activity 11/788 166/18639 0.0662650602409639 1.56740413430371 0.094233757369025 0.406360339113498 GO:0005160 transforming growth factor beta receptor binding 3/788 26/18639 0.115384615384615 2.72925614994143 0.0952968936859087 0.406360339113498 GO:0016289 acyl-CoA hydrolase activity 3/788 26/18639 0.115384615384615 2.72925614994143 0.0952968936859087 0.406360339113498 GO:0097602 cullin family protein binding 3/788 26/18639 0.115384615384615 2.72925614994143 0.0952968936859087 0.406360339113498 GO:0051213 dioxygenase activity 7/788 93/18639 0.0752688172043011 1.78037497953168 0.0986400128931282 0.412357863345208 GO:0004402 histone acetyltransferase activity 4/788 42/18639 0.0952380952380952 2.25271936185642 0.100364433566636 0.412357863345208 GO:0031492 nucleosomal DNA binding 4/788 42/18639 0.0952380952380952 2.25271936185642 0.100364433566636 0.412357863345208 GO:0005200 structural constituent of cytoskeleton 8/788 112/18639 0.0714285714285714 1.68953952139231 0.101986233623136 0.412357863345208 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 2/788 13/18639 0.153846153846154 3.63900819992191 0.102339795139282 0.412357863345208 GO:0004535 poly(A)-specific ribonuclease activity 2/788 13/18639 0.153846153846154 3.63900819992191 0.102339795139282 0.412357863345208 GO:0046975 histone H3K36 methyltransferase activity 2/788 13/18639 0.153846153846154 3.63900819992191 0.102339795139282 0.412357863345208 GO:0097157 pre-mRNA intronic binding 2/788 13/18639 0.153846153846154 3.63900819992191 0.102339795139282 0.412357863345208 GO:0140666 annealing activity 2/788 13/18639 0.153846153846154 3.63900819992191 0.102339795139282 0.412357863345208 GO:0016410 N-acyltransferase activity 7/788 94/18639 0.074468085106383 1.76143482017496 0.102924945618072 0.412357863345208 GO:0036002 pre-mRNA binding 5/788 59/18639 0.0847457627118644 2.00453841521122 0.103368001500785 0.412357863345208 GO:0031072 heat shock protein binding 9/788 131/18639 0.0687022900763359 1.6250532801178 0.103555261479609 0.412357863345208 GO:0046982 protein heterodimerization activity 21/788 369/18639 0.0569105691056911 1.34613717964591 0.103615030356051 0.412357863345208 GO:0005385 zinc ion transmembrane transporter activity 3/788 27/18639 0.111111111111111 2.62817258883249 0.104001761994145 0.412357863345208 GO:0008320 protein transmembrane transporter activity 3/788 27/18639 0.111111111111111 2.62817258883249 0.104001761994145 0.412357863345208 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/788 27/18639 0.111111111111111 2.62817258883249 0.104001761994145 0.412357863345208 GO:0008276 protein methyltransferase activity 7/788 95/18639 0.0736842105263158 1.74289340101523 0.107309274414754 0.423613904239904 GO:0003924 GTPase activity 19/788 331/18639 0.0574018126888218 1.35775683592252 0.110222967346662 0.433224184701662 GO:0036408 histone H3K14 acetyltransferase activity 3/788 28/18639 0.107142857142857 2.53430928208847 0.113006502071376 0.433976935314884 GO:0046966 nuclear thyroid hormone receptor binding 3/788 28/18639 0.107142857142857 2.53430928208847 0.113006502071376 0.433976935314884 GO:0051959 dynein light intermediate chain binding 3/788 28/18639 0.107142857142857 2.53430928208847 0.113006502071376 0.433976935314884 GO:0141052 histone H3 demethylase activity 3/788 28/18639 0.107142857142857 2.53430928208847 0.113006502071376 0.433976935314884 GO:0017124 SH3 domain binding 8/788 115/18639 0.0695652173913043 1.64546457735599 0.114103965441652 0.433976935314884 GO:0001046 core promoter sequence-specific DNA binding 4/788 44/18639 0.0909090909090909 2.15032302722658 0.114163353596847 0.433976935314884 GO:0043014 alpha-tubulin binding 4/788 44/18639 0.0909090909090909 2.15032302722658 0.114163353596847 0.433976935314884 GO:0019905 syntaxin binding 5/788 61/18639 0.0819672131147541 1.93881584422069 0.11493293353646 0.433976935314884 GO:0030983 mismatched DNA binding 2/788 14/18639 0.142857142857143 3.37907904278463 0.116175241533409 0.433976935314884 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 2/788 14/18639 0.142857142857143 3.37907904278463 0.116175241533409 0.433976935314884 GO:0061665 SUMO ligase activity 2/788 14/18639 0.142857142857143 3.37907904278463 0.116175241533409 0.433976935314884 GO:0098847 sequence-specific single stranded DNA binding 2/788 14/18639 0.142857142857143 3.37907904278463 0.116175241533409 0.433976935314884 GO:0045296 cadherin binding 19/788 334/18639 0.0568862275449102 1.34556141524058 0.117317878508583 0.43644181963687 GO:0010484 histone H3 acetyltransferase activity 3/788 29/18639 0.103448275862069 2.44691930684404 0.122294883849869 0.451243163266454 GO:0051861 glycolipid binding 3/788 29/18639 0.103448275862069 2.44691930684404 0.122294883849869 0.451243163266454 GO:0004467 long-chain fatty acid-CoA ligase activity 2/788 15/18639 0.133333333333333 3.15380710659898 0.130446165209806 0.458433951381386 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/788 15/18639 0.133333333333333 3.15380710659898 0.130446165209806 0.458433951381386 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/788 15/18639 0.133333333333333 3.15380710659898 0.130446165209806 0.458433951381386 GO:0017081 chloride channel regulator activity 2/788 15/18639 0.133333333333333 3.15380710659898 0.130446165209806 0.458433951381386 GO:0048531 beta-1,3-galactosyltransferase activity 2/788 15/18639 0.133333333333333 3.15380710659898 0.130446165209806 0.458433951381386 GO:0141050 histone H3K deacetylase activity 2/788 15/18639 0.133333333333333 3.15380710659898 0.130446165209806 0.458433951381386 GO:0141051 histone H4K deacetylase activity 2/788 15/18639 0.133333333333333 3.15380710659898 0.130446165209806 0.458433951381386 GO:0043130 ubiquitin binding 7/788 100/18639 0.07 1.65574873096447 0.130686364959246 0.458433951381386 GO:0008187 poly-pyrimidine tract binding 3/788 30/18639 0.1 2.36535532994924 0.131850472742434 0.458433951381386 GO:0032452 histone demethylase activity 3/788 30/18639 0.1 2.36535532994924 0.131850472742434 0.458433951381386 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/788 30/18639 0.1 2.36535532994924 0.131850472742434 0.458433951381386 GO:0043995 histone H4K5 acetyltransferase activity 3/788 30/18639 0.1 2.36535532994924 0.131850472742434 0.458433951381386 GO:0043996 histone H4K8 acetyltransferase activity 3/788 30/18639 0.1 2.36535532994924 0.131850472742434 0.458433951381386 GO:0043997 histone H4K12 acetyltransferase activity 3/788 30/18639 0.1 2.36535532994924 0.131850472742434 0.458433951381386 GO:0051721 protein phosphatase 2A binding 3/788 30/18639 0.1 2.36535532994924 0.131850472742434 0.458433951381386 GO:0061733 protein-lysine-acetyltransferase activity 4/788 47/18639 0.0851063829787234 2.01306836591425 0.136310740979659 0.46676102214247 GO:0061749 forked DNA-dependent helicase activity 4/788 47/18639 0.0851063829787234 2.01306836591425 0.136310740979659 0.46676102214247 GO:0140938 histone H3 methyltransferase activity 4/788 47/18639 0.0851063829787234 2.01306836591425 0.136310740979659 0.46676102214247 GO:1990518 single-stranded 3'-5' DNA helicase activity 4/788 47/18639 0.0851063829787234 2.01306836591425 0.136310740979659 0.46676102214247 GO:0140457 protein demethylase activity 3/788 31/18639 0.0967741935483871 2.28905354511217 0.141656719513645 0.483236507322018 GO:0009378 four-way junction helicase activity 4/788 48/18639 0.0833333333333333 1.97112944162437 0.144052655839537 0.484102605497923 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 4/788 48/18639 0.0833333333333333 1.97112944162437 0.144052655839537 0.484102605497923 GO:0036121 double-stranded DNA helicase activity 4/788 48/18639 0.0833333333333333 1.97112944162437 0.144052655839537 0.484102605497923 GO:0043138 3'-5' DNA helicase activity 4/788 48/18639 0.0833333333333333 1.97112944162437 0.144052655839537 0.484102605497923 GO:0070411 I-SMAD binding 2/788 16/18639 0.125 2.95669416243655 0.145091135785767 0.484678678118019 GO:0140098 catalytic activity, acting on RNA 21/788 387/18639 0.0542635658914729 1.28352614803447 0.145768281263489 0.484678678118019 GO:0004722 protein serine/threonine phosphatase activity 7/788 103/18639 0.0679611650485437 1.60752303977133 0.145832522619581 0.484678678118019 GO:0035091 phosphatidylinositol binding 16/788 284/18639 0.0563380281690141 1.33259455208408 0.149655452432918 0.495562377287025 GO:0008378 galactosyltransferase activity 3/788 32/18639 0.09375 2.21752062182741 0.151697041107438 0.496862772322912 GO:0022884 macromolecule transmembrane transporter activity 3/788 32/18639 0.09375 2.21752062182741 0.151697041107438 0.496862772322912 GO:0140142 nucleocytoplasmic carrier activity 3/788 32/18639 0.09375 2.21752062182741 0.151697041107438 0.496862772322912 GO:1990841 promoter-specific chromatin binding 5/788 68/18639 0.0735294117647059 1.73923186025679 0.159851069091478 0.506944664110325 GO:0032813 tumor necrosis factor receptor superfamily binding 4/788 50/18639 0.08 1.89228426395939 0.160032761382086 0.506944664110325 GO:0005092 GDP-dissociation inhibitor activity 2/788 17/18639 0.117647058823529 2.78277097641087 0.160053127024609 0.506944664110325 GO:0008484 sulfuric ester hydrolase activity 2/788 17/18639 0.117647058823529 2.78277097641087 0.160053127024609 0.506944664110325 GO:0032183 SUMO binding 2/788 17/18639 0.117647058823529 2.78277097641087 0.160053127024609 0.506944664110325 GO:0032977 membrane insertase activity 2/788 17/18639 0.117647058823529 2.78277097641087 0.160053127024609 0.506944664110325 GO:0046965 nuclear retinoid X receptor binding 2/788 17/18639 0.117647058823529 2.78277097641087 0.160053127024609 0.506944664110325 GO:0070402 NADPH binding 2/788 17/18639 0.117647058823529 2.78277097641087 0.160053127024609 0.506944664110325 GO:0070403 NAD+ binding 2/788 17/18639 0.117647058823529 2.78277097641087 0.160053127024609 0.506944664110325 GO:0140857 histone H3T45 kinase activity 14/788 246/18639 0.0569105691056911 1.34613717964591 0.160382935769417 0.506944664110325 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3/788 33/18639 0.0909090909090909 2.15032302722658 0.161954893109778 0.510129698157629 GO:0004197 cysteine-type endopeptidase activity 6/788 88/18639 0.0681818181818182 1.61274227041994 0.16834431697323 0.526907400216806 GO:0061630 ubiquitin protein ligase activity 19/788 353/18639 0.0538243626062323 1.27313742971772 0.168447166662231 0.526907400216806 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 10/788 167/18639 0.0598802395209581 1.41638043709535 0.170373902960171 0.53109658026205 GO:0015035 protein-disulfide reductase activity 3/788 34/18639 0.0882352941176471 2.08707823230815 0.172413834480776 0.531719619245418 GO:0016831 carboxy-lyase activity 3/788 34/18639 0.0882352941176471 2.08707823230815 0.172413834480776 0.531719619245418 GO:0005096 GTPase activator activity 15/788 271/18639 0.0553505535055351 1.30923726749958 0.175159861295226 0.531719619245418 GO:0008409 5'-3' exonuclease activity 2/788 18/18639 0.111111111111111 2.62817258883249 0.175279255016742 0.531719619245418 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/788 18/18639 0.111111111111111 2.62817258883249 0.175279255016742 0.531719619245418 GO:0017075 syntaxin-1 binding 2/788 18/18639 0.111111111111111 2.62817258883249 0.175279255016742 0.531719619245418 GO:0050811 GABA receptor binding 2/788 18/18639 0.111111111111111 2.62817258883249 0.175279255016742 0.531719619245418 GO:0070628 proteasome binding 2/788 18/18639 0.111111111111111 2.62817258883249 0.175279255016742 0.531719619245418 GO:0000287 magnesium ion binding 13/788 230/18639 0.0565217391304348 1.33693996910174 0.177279257670724 0.535988123526202 GO:0019210 kinase inhibitor activity 6/788 90/18639 0.0666666666666667 1.57690355329949 0.180846392819659 0.544950463696574 GO:0003756 protein disulfide isomerase activity 2/788 19/18639 0.105263157894737 2.48984771573604 0.190720530582641 0.566881215502256 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/788 19/18639 0.105263157894737 2.48984771573604 0.190720530582641 0.566881215502256 GO:0070003 threonine-type peptidase activity 2/788 19/18639 0.105263157894737 2.48984771573604 0.190720530582641 0.566881215502256 GO:0106310 protein serine kinase activity 19/788 361/18639 0.0526315789473684 1.24492385786802 0.193035213066095 0.566881215502256 GO:0003925 G protein activity 4/788 54/18639 0.0740740740740741 1.75211505922166 0.193768026095351 0.566881215502256 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 4/788 54/18639 0.0740740740740741 1.75211505922166 0.193768026095351 0.566881215502256 GO:0050661 NADP binding 4/788 54/18639 0.0740740740740741 1.75211505922166 0.193768026095351 0.566881215502256 GO:0051287 NAD binding 4/788 54/18639 0.0740740740740741 1.75211505922166 0.193768026095351 0.566881215502256 GO:0140463 chromatin-protein adaptor activity 4/788 54/18639 0.0740740740740741 1.75211505922166 0.193768026095351 0.566881215502256 GO:0015631 tubulin binding 20/788 385/18639 0.051948051948052 1.22875601555805 0.20107483388382 0.586360160745076 GO:0140313 molecular sequestering activity 4/788 55/18639 0.0727272727272727 1.72025842178126 0.202526886638616 0.588695516145689 GO:0023023 MHC protein complex binding 3/788 37/18639 0.0810810810810811 1.91785567293182 0.204835498928774 0.590265155536846 GO:0016004 phospholipase activator activity 2/788 20/18639 0.1 2.36535532994924 0.206331625165535 0.590265155536846 GO:0030742 GTP-dependent protein binding 2/788 20/18639 0.1 2.36535532994924 0.206331625165535 0.590265155536846 GO:0042288 MHC class I protein binding 2/788 20/18639 0.1 2.36535532994924 0.206331625165535 0.590265155536846 GO:0061608 nuclear import signal receptor activity 2/788 20/18639 0.1 2.36535532994924 0.206331625165535 0.590265155536846 GO:0004721 phosphoprotein phosphatase activity 10/788 175/18639 0.0571428571428571 1.35163161711385 0.207286826286454 0.591127100829508 GO:0001221 transcription coregulator binding 7/788 115/18639 0.0608695652173913 1.43978150518649 0.213836307061131 0.606230397646481 GO:0004674 protein serine/threonine kinase activity 22/788 433/18639 0.0508083140877598 1.20179716533218 0.2157631092096 0.606230397646481 GO:0016779 nucleotidyltransferase activity 8/788 136/18639 0.0588235294117647 1.39138548820543 0.218104440438841 0.606230397646481 GO:0140789 histone phosphatase activity 8/788 136/18639 0.0588235294117647 1.39138548820543 0.218104440438841 0.606230397646481 GO:0004601 peroxidase activity 4/788 57/18639 0.0701754385964912 1.65989847715736 0.220380309195581 0.606230397646481 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/788 21/18639 0.0952380952380952 2.25271936185642 0.22207064951795 0.606230397646481 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/788 21/18639 0.0952380952380952 2.25271936185642 0.22207064951795 0.606230397646481 GO:0070182 DNA polymerase binding 2/788 21/18639 0.0952380952380952 2.25271936185642 0.22207064951795 0.606230397646481 GO:0072542 protein phosphatase activator activity 2/788 21/18639 0.0952380952380952 2.25271936185642 0.22207064951795 0.606230397646481 GO:0140312 cargo adaptor activity 2/788 21/18639 0.0952380952380952 2.25271936185642 0.22207064951795 0.606230397646481 GO:1904047 S-adenosyl-L-methionine binding 2/788 21/18639 0.0952380952380952 2.25271936185642 0.22207064951795 0.606230397646481 GO:0019208 phosphatase regulator activity 7/788 117/18639 0.0598290598290598 1.41516985552519 0.226167740775738 0.606230397646481 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/788 39/18639 0.0769230769230769 1.81950409996095 0.227163403785273 0.606230397646481 GO:0017116 single-stranded DNA helicase activity 4/788 58/18639 0.0689655172413793 1.63127953789603 0.229459341035068 0.606230397646481 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 13/788 243/18639 0.0534979423868313 1.26541643166009 0.230087840760314 0.606230397646481 GO:0008649 rRNA methyltransferase activity 2/788 22/18639 0.0909090909090909 2.15032302722658 0.237898944520898 0.606230397646481 GO:0061133 endopeptidase activator activity 2/788 22/18639 0.0909090909090909 2.15032302722658 0.237898944520898 0.606230397646481 GO:0070034 telomerase RNA binding 2/788 22/18639 0.0909090909090909 2.15032302722658 0.237898944520898 0.606230397646481 GO:0140517 protein-RNA adaptor activity 2/788 22/18639 0.0909090909090909 2.15032302722658 0.237898944520898 0.606230397646481 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/788 40/18639 0.075 1.77401649746193 0.238495877972824 0.606230397646481 GO:0071949 FAD binding 3/788 40/18639 0.075 1.77401649746193 0.238495877972824 0.606230397646481 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4/788 59/18639 0.0677966101694915 1.60363073216898 0.238629620273925 0.606230397646481 GO:0004676 3-phosphoinositide-dependent protein kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:0004711 ribosomal protein S6 kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:0035175 histone H3S10 kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:0035979 histone H2AXS139 kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:0044022 histone H3S28 kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:0044023 histone H4S1 kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:0044024 histone H2AS1 kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:0044025 histone H2BS14 kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:0072354 histone H3T3 kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:0072371 histone H2AS121 kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:0072518 Rho-dependent protein serine/threonine kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:0140823 histone H2BS36 kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:0140855 histone H3S57 kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:0140995 histone H2A kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:0140997 histone H4 kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:0140998 histone H2B kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:1990244 histone H2AT120 kinase activity 13/788 245/18639 0.0530612244897959 1.25508650160572 0.23873674951565 0.606230397646481 GO:0016757 glycosyltransferase activity 14/788 267/18639 0.052434456928839 1.24026122169623 0.241150186311143 0.610448565491807 GO:0046332 SMAD binding 5/788 79/18639 0.0632911392405063 1.49706033541091 0.241748436334145 0.610448565491807 GO:0004677 DNA-dependent protein kinase activity 13/788 246/18639 0.0528455284552846 1.24998452395691 0.243108421527242 0.612172738330436 GO:0008168 methyltransferase activity 11/788 204/18639 0.053921568627451 1.27543669752165 0.246234583640825 0.616724037269631 GO:0035402 histone H3T11 kinase activity 13/788 247/18639 0.0526315789473684 1.24492385786802 0.247510632537715 0.616724037269631 GO:0035403 histone H3T6 kinase activity 13/788 247/18639 0.0526315789473684 1.24492385786802 0.247510632537715 0.616724037269631 GO:0003779 actin binding 22/788 443/18639 0.0496613995485327 1.17466856114861 0.247644718505394 0.616724037269631 GO:0042287 MHC protein binding 3/788 41/18639 0.0731707317073171 1.73074780240188 0.249921319361978 0.619659877043401 GO:0004679 AMP-activated protein kinase activity 13/788 248/18639 0.0524193548387097 1.23990400360242 0.251942665102465 0.619659877043401 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/788 23/18639 0.0869565217391304 2.05683072169499 0.253780883507402 0.619659877043401 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/788 23/18639 0.0869565217391304 2.05683072169499 0.253780883507402 0.619659877043401 GO:0015078 proton transmembrane transporter activity 10/788 185/18639 0.0540540540540541 1.27857044862121 0.257574215980767 0.619659877043401 GO:0033192 calmodulin-dependent protein phosphatase activity 5/788 81/18639 0.0617283950617284 1.46009588268472 0.257734639124247 0.619659877043401 GO:0140791 histone H2AXS140 phosphatase activity 5/788 81/18639 0.0617283950617284 1.46009588268472 0.257734639124247 0.619659877043401 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 5/788 81/18639 0.0617283950617284 1.46009588268472 0.257734639124247 0.619659877043401 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 5/788 81/18639 0.0617283950617284 1.46009588268472 0.257734639124247 0.619659877043401 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 5/788 81/18639 0.0617283950617284 1.46009588268472 0.257734639124247 0.619659877043401 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 5/788 81/18639 0.0617283950617284 1.46009588268472 0.257734639124247 0.619659877043401 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 5/788 81/18639 0.0617283950617284 1.46009588268472 0.257734639124247 0.619659877043401 GO:1990439 MAP kinase serine/threonine phosphatase activity 5/788 81/18639 0.0617283950617284 1.46009588268472 0.257734639124247 0.619659877043401 GO:0004520 DNA endonuclease activity 3/788 42/18639 0.0714285714285714 1.68953952139231 0.261425695192389 0.625208540883386 GO:0048487 beta-tubulin binding 3/788 42/18639 0.0714285714285714 1.68953952139231 0.261425695192389 0.625208540883386 GO:0019955 cytokine binding 8/788 144/18639 0.0555555555555556 1.31408629441624 0.264876576613561 0.630714801424813 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 5/788 82/18639 0.0609756097560976 1.4422898353349 0.26582117183944 0.630714801424813 GO:0033549 MAP kinase phosphatase activity 5/788 82/18639 0.0609756097560976 1.4422898353349 0.26582117183944 0.630714801424813 GO:0050699 WW domain binding 2/788 24/18639 0.0833333333333333 1.97112944162437 0.269683685493414 0.632940578671398 GO:0060229 lipase activator activity 2/788 24/18639 0.0833333333333333 1.97112944162437 0.269683685493414 0.632940578671398 GO:0070300 phosphatidic acid binding 2/788 24/18639 0.0833333333333333 1.97112944162437 0.269683685493414 0.632940578671398 GO:0140033 acetylation-dependent protein binding 2/788 24/18639 0.0833333333333333 1.97112944162437 0.269683685493414 0.632940578671398 GO:0004518 nuclease activity 11/788 209/18639 0.0526315789473684 1.24492385786802 0.270960181356008 0.632940578671398 GO:0051015 actin filament binding 11/788 209/18639 0.0526315789473684 1.24492385786802 0.270960181356008 0.632940578671398 GO:0008375 acetylglucosaminyltransferase activity 3/788 43/18639 0.0697674418604651 1.65024790461575 0.272995396725209 0.635033795725362 GO:0001540 amyloid-beta binding 5/788 83/18639 0.0602409638554217 1.42491284936701 0.273963695058508 0.635033795725362 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 5/788 83/18639 0.0602409638554217 1.42491284936701 0.273963695058508 0.635033795725362 GO:0004860 protein kinase inhibitor activity 5/788 84/18639 0.0595238095238095 1.40794960116026 0.28215751438974 0.648647798565535 GO:0017018 myosin phosphatase activity 5/788 84/18639 0.0595238095238095 1.40794960116026 0.28215751438974 0.648647798565535 GO:0008139 nuclear localization sequence binding 2/788 25/18639 0.08 1.89228426395939 0.285577238748985 0.648647798565535 GO:0015645 fatty acid ligase activity 2/788 25/18639 0.08 1.89228426395939 0.285577238748985 0.648647798565535 GO:0019211 phosphatase activator activity 2/788 25/18639 0.08 1.89228426395939 0.285577238748985 0.648647798565535 GO:0019706 protein-cysteine S-palmitoyltransferase activity 2/788 25/18639 0.08 1.89228426395939 0.285577238748985 0.648647798565535 GO:0019707 protein-cysteine S-acyltransferase activity 2/788 25/18639 0.08 1.89228426395939 0.285577238748985 0.648647798565535 GO:0120515 fatty acid-CoA ligase activity 2/788 25/18639 0.08 1.89228426395939 0.285577238748985 0.648647798565535 GO:0019209 kinase activator activity 8/788 148/18639 0.0540540540540541 1.27857044862121 0.289297191290108 0.65545027801067 GO:0000149 SNARE binding 6/788 106/18639 0.0566037735849057 1.33888037544297 0.291650207188891 0.659129468246893 GO:0004715 non-membrane spanning protein tyrosine kinase activity 3/788 45/18639 0.0666666666666667 1.57690355329949 0.296278544815852 0.667487510399493 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 5/788 86/18639 0.0581395348837209 1.37520658717979 0.298680424441287 0.667487510399493 GO:0016209 antioxidant activity 5/788 86/18639 0.0581395348837209 1.37520658717979 0.298680424441287 0.667487510399493 GO:0050660 flavin adenine dinucleotide binding 5/788 86/18639 0.0581395348837209 1.37520658717979 0.298680424441287 0.667487510399493 GO:0019888 protein phosphatase regulator activity 6/788 107/18639 0.0560747663551402 1.32636747473789 0.299040311628092 0.667487510399493 GO:0005112 Notch binding 2/788 26/18639 0.0769230769230769 1.81950409996095 0.301433934170908 0.669906405320219 GO:0016741 transferase activity, transferring one-carbon groups 11/788 215/18639 0.0511627906976744 1.21018179671822 0.301606091775807 0.669906405320219 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/788 46/18639 0.0652173913043478 1.54262304127124 0.307967007880134 0.682358272361866 GO:0046906 tetrapyrrole binding 8/788 152/18639 0.0526315789473684 1.24492385786802 0.314246808858616 0.691472894588086 GO:0008173 RNA methyltransferase activity 4/788 67/18639 0.0597014925373134 1.41215243579059 0.314375397871353 0.691472894588086 GO:0042054 histone methyltransferase activity 4/788 67/18639 0.0597014925373134 1.41215243579059 0.314375397871353 0.691472894588086 GO:0008266 poly(U) RNA binding 2/788 27/18639 0.0740740740740741 1.75211505922166 0.31722850794505 0.69269220092349 GO:0016405 CoA-ligase activity 2/788 27/18639 0.0740740740740741 1.75211505922166 0.31722850794505 0.69269220092349 GO:0023026 MHC class II protein complex binding 2/788 27/18639 0.0740740740740741 1.75211505922166 0.31722850794505 0.69269220092349 GO:0043495 protein-membrane adaptor activity 3/788 47/18639 0.0638297872340425 1.50980127443568 0.319670844259712 0.696343236652482 GO:0003727 single-stranded RNA binding 5/788 89/18639 0.0561797752808989 1.32885130896025 0.323734255852733 0.700126968371713 GO:0140223 general transcription initiation factor activity 4/788 68/18639 0.0588235294117647 1.39138548820543 0.324033168420095 0.700126968371713 GO:0030695 GTPase regulator activity 23/788 489/18639 0.0470347648261759 1.11253931674504 0.328860363227582 0.700126968371713 GO:1902936 phosphatidylinositol bisphosphate binding 6/788 111/18639 0.0540540540540541 1.27857044862121 0.328919795784086 0.700126968371713 GO:0141003 histone H2AX kinase activity 17/788 354/18639 0.0480225988700565 1.13590510195302 0.329426858374681 0.700126968371713 GO:0060589 nucleoside-triphosphatase regulator activity 23/788 490/18639 0.0469387755102041 1.11026882834352 0.332409241015641 0.700126968371713 GO:0016866 intramolecular transferase activity 2/788 28/18639 0.0714285714285714 1.68953952139231 0.332937893012255 0.700126968371713 GO:0019789 SUMO transferase activity 2/788 28/18639 0.0714285714285714 1.68953952139231 0.332937893012255 0.700126968371713 GO:0046875 ephrin receptor binding 2/788 28/18639 0.0714285714285714 1.68953952139231 0.332937893012255 0.700126968371713 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/788 28/18639 0.0714285714285714 1.68953952139231 0.332937893012255 0.700126968371713 GO:0097718 disordered domain specific binding 2/788 28/18639 0.0714285714285714 1.68953952139231 0.332937893012255 0.700126968371713 GO:0140996 histone H3 kinase activity 17/788 357/18639 0.0476190476190476 1.12635968092821 0.341982691367514 0.700126968371713 GO:0016417 S-acyltransferase activity 2/788 29/18639 0.0689655172413793 1.63127953789603 0.348541078876136 0.700126968371713 GO:0052689 carboxylic ester hydrolase activity 5/788 92/18639 0.0543478260869565 1.28551920105937 0.349004369767355 0.700126968371713 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0005031 tumor necrosis factor receptor activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0005131 growth hormone receptor binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0005381 iron ion transmembrane transporter activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0005528 FK506 binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0016783 sulfurtransferase activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0016868 intramolecular phosphotransferase activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0030957 Tat protein binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0031419 cobalamin binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0035256 G protein-coupled glutamate receptor binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0042975 peroxisome proliferator activated receptor binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0043422 protein kinase B binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0047429 nucleoside triphosphate diphosphatase activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0050815 phosphoserine residue binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0070513 death domain binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0097177 mitochondrial ribosome binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0099122 RNA polymerase II C-terminal domain binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0141109 transporter activator activity 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:1905394 retromer complex binding 1/788 10/18639 0.1 2.36535532994924 0.350837960920781 0.700126968371713 GO:0035173 histone kinase activity 17/788 360/18639 0.0472222222222222 1.11697335025381 0.35464314027068 0.700680519766713 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 9/788 181/18639 0.0497237569060773 1.1761435342289 0.357673926146842 0.700680519766713 GO:0070566 adenylyltransferase activity 2/788 30/18639 0.0666666666666667 1.57690355329949 0.364018979314258 0.700680519766713 GO:0016830 carbon-carbon lyase activity 3/788 51/18639 0.0588235294117647 1.39138548820543 0.366420358202532 0.700680519766713 GO:0016791 phosphatase activity 13/788 273/18639 0.0476190476190476 1.12635968092821 0.370181330883186 0.700680519766713 GO:0030295 protein kinase activator activity 7/788 139/18639 0.0503597122302158 1.19118613738451 0.373307410398473 0.700680519766713 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 11/788 229/18639 0.0480349344978166 1.13619688338173 0.375999667161203 0.700680519766713 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0004523 RNA-DNA hybrid ribonuclease activity 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0005114 type II transforming growth factor beta receptor binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0008172 S-methyltransferase activity 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0019107 myristoyltransferase activity 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0019206 nucleoside kinase activity 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0032404 mismatch repair complex binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0034056 estrogen response element binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0034713 type I transforming growth factor beta receptor binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0048185 activin binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0140031 phosphorylation-dependent protein binding 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0180030 inositol phosphate kinase activity 1/788 11/18639 0.0909090909090909 2.15032302722658 0.378297281699912 0.700680519766713 GO:0008327 methyl-CpG binding 2/788 31/18639 0.0645161290322581 1.52603569674144 0.379354307576368 0.700680519766713 GO:0017147 Wnt-protein binding 2/788 31/18639 0.0645161290322581 1.52603569674144 0.379354307576368 0.700680519766713 GO:0003678 DNA helicase activity 4/788 74/18639 0.0540540540540541 1.27857044862121 0.382162706543533 0.700680519766713 GO:0031491 nucleosome binding 4/788 74/18639 0.0540540540540541 1.27857044862121 0.382162706543533 0.700680519766713 GO:0035064 methylated histone binding 4/788 74/18639 0.0540540540540541 1.27857044862121 0.382162706543533 0.700680519766713 GO:0005246 calcium channel regulator activity 3/788 53/18639 0.0566037735849057 1.33888037544297 0.389615032064362 0.700680519766713 GO:0016251 RNA polymerase II general transcription initiation factor activity 3/788 53/18639 0.0566037735849057 1.33888037544297 0.389615032064362 0.700680519766713 GO:0016860 intramolecular oxidoreductase activity 3/788 53/18639 0.0566037735849057 1.33888037544297 0.389615032064362 0.700680519766713 GO:0020037 heme binding 7/788 142/18639 0.0492957746478873 1.16602023307357 0.394192986641692 0.700680519766713 GO:0030515 snoRNA binding 2/788 32/18639 0.0625 1.47834708121827 0.394531458674297 0.700680519766713 GO:0043425 bHLH transcription factor binding 2/788 32/18639 0.0625 1.47834708121827 0.394531458674297 0.700680519766713 GO:0004725 protein tyrosine phosphatase activity 5/788 98/18639 0.0510204081632653 1.20681394385165 0.399736906118736 0.700680519766713 GO:0017022 myosin binding 4/788 76/18639 0.0526315789473684 1.24492385786802 0.401464910062797 0.700680519766713 GO:0051536 iron-sulfur cluster binding 4/788 76/18639 0.0526315789473684 1.24492385786802 0.401464910062797 0.700680519766713 GO:0140034 methylation-dependent protein binding 4/788 76/18639 0.0526315789473684 1.24492385786802 0.401464910062797 0.700680519766713 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0003720 telomerase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0004300 enoyl-CoA hydratase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0004859 phospholipase inhibitor activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0005025 transforming growth factor beta receptor activity, type I 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0005026 transforming growth factor beta receptor activity, type II 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0005049 nuclear export signal receptor activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0005527 macrolide binding 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0015368 calcium:monoatomic cation antiporter activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0016208 AMP binding 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0016273 arginine N-methyltransferase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0016274 protein-arginine N-methyltransferase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0016361 activin receptor activity, type I 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0016362 activin receptor activity, type II 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0016423 tRNA (guanine) methyltransferase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0017002 activin receptor activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0017166 vinculin binding 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0031543 peptidyl-proline dioxygenase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0035259 nuclear glucocorticoid receptor binding 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0035497 cAMP response element binding 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0045295 gamma-catenin binding 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0070008 serine-type exopeptidase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0070410 co-SMAD binding 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0070679 inositol 1,4,5 trisphosphate binding 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:1990459 transferrin receptor binding 1/788 12/18639 0.0833333333333333 1.97112944162437 0.404596494821045 0.700680519766713 GO:0003724 RNA helicase activity 4/788 77/18639 0.051948051948052 1.22875601555805 0.411077069811288 0.709186395246955 GO:0051540 metal cluster binding 4/788 77/18639 0.051948051948052 1.22875601555805 0.411077069811288 0.709186395246955 GO:0019902 phosphatase binding 9/788 190/18639 0.0473684210526316 1.12043147208122 0.412075417304268 0.70955462332011 GO:0008194 UDP-glycosyltransferase activity 7/788 145/18639 0.0482758620689655 1.14189567652722 0.415080741896663 0.713370704704532 GO:0015020 glucuronosyltransferase activity 2/788 34/18639 0.0588235294117647 1.39138548820543 0.424356558632348 0.71752619444298 GO:0030332 cyclin binding 2/788 34/18639 0.0588235294117647 1.39138548820543 0.424356558632348 0.71752619444298 GO:0003964 RNA-directed DNA polymerase activity 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.71752619444298 GO:0005035 death receptor activity 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.71752619444298 GO:0005172 vascular endothelial growth factor receptor binding 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.71752619444298 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.71752619444298 GO:0008253 5'-nucleotidase activity 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.71752619444298 GO:0009982 pseudouridine synthase activity 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.71752619444298 GO:0031994 insulin-like growth factor I binding 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.71752619444298 GO:0035673 oligopeptide transmembrane transporter activity 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.71752619444298 GO:0070123 transforming growth factor beta receptor activity, type III 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.71752619444298 GO:0089720 caspase binding 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.71752619444298 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.71752619444298 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.71752619444298 GO:0140852 histone ubiquitin ligase activity 1/788 13/18639 0.0769230769230769 1.81950409996095 0.429784553127859 0.71752619444298 GO:0008186 ATP-dependent activity, acting on RNA 4/788 79/18639 0.0506329113924051 1.19764826832873 0.43019822719922 0.71752619444298 GO:0005154 epidermal growth factor receptor binding 2/788 35/18639 0.0571428571428571 1.35163161711385 0.438980738843456 0.729482698372214 GO:0043015 gamma-tubulin binding 2/788 35/18639 0.0571428571428571 1.35163161711385 0.438980738843456 0.729482698372214 GO:0005543 phospholipid binding 22/788 497/18639 0.0442655935613682 1.04703857663749 0.44329026397343 0.729627432747356 GO:0016409 palmitoyltransferase activity 2/788 36/18639 0.0555555555555556 1.31408629441624 0.45339901306825 0.729627432747356 GO:0045505 dynein intermediate chain binding 2/788 36/18639 0.0555555555555556 1.31408629441624 0.45339901306825 0.729627432747356 GO:0004705 JUN kinase activity 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.729627432747356 GO:0005545 1-phosphatidylinositol binding 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.729627432747356 GO:0008174 mRNA methyltransferase activity 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.729627432747356 GO:0008195 phosphatidate phosphatase activity 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.729627432747356 GO:0008559 ABC-type xenobiotic transporter activity 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.729627432747356 GO:0015926 glucosidase activity 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.729627432747356 GO:0016530 metallochaperone activity 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.729627432747356 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.729627432747356 GO:0031404 chloride ion binding 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.729627432747356 GO:0032454 histone H3K9 demethylase activity 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.729627432747356 GO:0044548 S100 protein binding 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.729627432747356 GO:0046030 inositol trisphosphate phosphatase activity 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.729627432747356 GO:0098821 BMP receptor activity 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.729627432747356 GO:1901612 cardiolipin binding 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.729627432747356 GO:1990825 sequence-specific mRNA binding 1/788 14/18639 0.0714285714285714 1.68953952139231 0.453908346327432 0.729627432747356 GO:0016758 hexosyltransferase activity 9/788 197/18639 0.0456852791878173 1.08061918627123 0.454402925483143 0.729627432747356 GO:0045309 protein phosphorylated amino acid binding 3/788 59/18639 0.0508474576271186 1.20272304912673 0.45765744262941 0.732251908207056 GO:0070888 E-box binding 3/788 59/18639 0.0508474576271186 1.20272304912673 0.45765744262941 0.732251908207056 GO:0035591 signaling adaptor activity 6/788 129/18639 0.0465116279069767 1.10016526974383 0.465064101033014 0.736152028848513 GO:0030165 PDZ domain binding 4/788 83/18639 0.0481927710843374 1.13993027949361 0.467898020964559 0.736152028848513 GO:0042578 phosphoric ester hydrolase activity 16/788 363/18639 0.0440771349862259 1.04258086168561 0.468427796466815 0.736152028848513 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 3/788 60/18639 0.05 1.18267766497462 0.468698177145346 0.736152028848513 GO:0003774 cytoskeletal motor activity 7/788 153/18639 0.0457516339869281 1.08218871304867 0.470363434957709 0.736152028848513 GO:0016798 hydrolase activity, acting on glycosyl bonds 6/788 130/18639 0.0461538461538462 1.09170245997657 0.472505536549751 0.736152028848513 GO:0000774 adenyl-nucleotide exchange factor activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.736152028848513 GO:0004089 carbonate dehydratase activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.736152028848513 GO:0005041 low-density lipoprotein particle receptor activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.736152028848513 GO:0008242 omega peptidase activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.736152028848513 GO:0008252 nucleotidase activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.736152028848513 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.736152028848513 GO:0031386 protein tag activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.736152028848513 GO:0042809 nuclear vitamin D receptor binding 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.736152028848513 GO:0045504 dynein heavy chain binding 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.736152028848513 GO:0050700 CARD domain binding 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.736152028848513 GO:0050780 dopamine receptor binding 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.736152028848513 GO:0061578 K63-linked deubiquitinase activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.736152028848513 GO:0140776 protein-containing complex destabilizing activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.736152028848513 GO:0141047 molecular tag activity 1/788 15/18639 0.0666666666666667 1.57690355329949 0.477012787835833 0.736152028848513 GO:0005506 iron ion binding 7/788 154/18639 0.0454545454545455 1.07516151361329 0.477195894806669 0.736152028848513 GO:0015026 coreceptor activity 3/788 61/18639 0.0491803278688525 1.16328950653241 0.479637047503792 0.738657395133608 GO:0000062 fatty-acyl-CoA binding 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.754554133389874 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.754554133389874 GO:0004707 MAP kinase activity 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.754554133389874 GO:0005024 transforming growth factor beta receptor activity 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.754554133389874 GO:0005159 insulin-like growth factor receptor binding 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.754554133389874 GO:0008296 3'-5'-DNA exonuclease activity 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.754554133389874 GO:0016722 oxidoreductase activity, acting on metal ions 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.754554133389874 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.754554133389874 GO:0043023 ribosomal large subunit binding 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.754554133389874 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.754554133389874 GO:0055102 lipase inhibitor activity 1/788 16/18639 0.0625 1.47834708121827 0.499140897972505 0.754554133389874 GO:0005507 copper ion binding 3/788 63/18639 0.0476190476190476 1.12635968092821 0.501188730174834 0.756384995121953 GO:0008017 microtubule binding 12/788 276/18639 0.0434782608695652 1.02841536084749 0.502258005941335 0.756735395618278 GO:0005085 guanyl-nucleotide exchange factor activity 10/788 230/18639 0.0434782608695652 1.02841536084749 0.509620421859811 0.766550518071995 GO:0004536 DNA nuclease activity 3/788 64/18639 0.046875 1.10876031091371 0.51179222475091 0.768538490323626 GO:0004549 tRNA-specific ribonuclease activity 1/788 17/18639 0.0588235294117647 1.39138548820543 0.520333883656748 0.770695458349767 GO:0008429 phosphatidylethanolamine binding 1/788 17/18639 0.0588235294117647 1.39138548820543 0.520333883656748 0.770695458349767 GO:0016018 cyclosporin A binding 1/788 17/18639 0.0588235294117647 1.39138548820543 0.520333883656748 0.770695458349767 GO:0031489 myosin V binding 1/788 17/18639 0.0588235294117647 1.39138548820543 0.520333883656748 0.770695458349767 GO:0048038 quinone binding 1/788 17/18639 0.0588235294117647 1.39138548820543 0.520333883656748 0.770695458349767 GO:1901567 fatty acid derivative binding 1/788 17/18639 0.0588235294117647 1.39138548820543 0.520333883656748 0.770695458349767 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 2/788 41/18639 0.0487804878048781 1.15383186826792 0.522133000906485 0.770695458349767 GO:0042169 SH2 domain binding 2/788 41/18639 0.0487804878048781 1.15383186826792 0.522133000906485 0.770695458349767 GO:0140828 metal cation:monoatomic cation antiporter activity 2/788 41/18639 0.0487804878048781 1.15383186826792 0.522133000906485 0.770695458349767 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 4/788 89/18639 0.0449438202247191 1.0630810471682 0.52260654421284 0.770695458349767 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 4/788 89/18639 0.0449438202247191 1.0630810471682 0.52260654421284 0.770695458349767 GO:0140793 histone H2AXY142 phosphatase activity 4/788 90/18639 0.0444444444444444 1.05126903553299 0.5314654800243 0.780719837279409 GO:0042056 chemoattractant activity 2/788 42/18639 0.0476190476190476 1.12635968092821 0.53516836619219 0.780719837279409 GO:0140767 enzyme-substrate adaptor activity 6/788 139/18639 0.0431654676258993 1.02101668918672 0.537913831079244 0.780719837279409 GO:0000900 mRNA regulatory element binding translation repressor activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.780719837279409 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.780719837279409 GO:0004706 JUN kinase kinase kinase activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.780719837279409 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.780719837279409 GO:0030228 lipoprotein particle receptor activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.780719837279409 GO:0031690 adrenergic receptor binding 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.780719837279409 GO:0035615 clathrin adaptor activity 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.780719837279409 GO:0070064 proline-rich region binding 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.780719837279409 GO:1901611 phosphatidylglycerol binding 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.780719837279409 GO:1990381 ubiquitin-specific protease binding 1/788 18/18639 0.0555555555555556 1.31408629441624 0.540631214753219 0.780719837279409 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3/788 67/18639 0.0447761194029851 1.05911432684294 0.542864715872933 0.782694901354277 GO:0008200 ion channel inhibitor activity 2/788 43/18639 0.0465116279069767 1.10016526974383 0.547957291532043 0.786785020466547 GO:0051219 phosphoprotein binding 4/788 93/18639 0.043010752688172 1.01735713116096 0.557541016246347 0.786785020466547 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.786785020466547 GO:0005520 insulin-like growth factor binding 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.786785020466547 GO:0008301 DNA binding, bending 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.786785020466547 GO:0008574 plus-end-directed microtubule motor activity 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.786785020466547 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.786785020466547 GO:0031420 alkali metal ion binding 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.786785020466547 GO:0042577 lipid phosphatase activity 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.786785020466547 GO:0042800 histone H3K4 methyltransferase activity 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.786785020466547 GO:0046624 sphingolipid transporter activity 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.786785020466547 GO:0050145 nucleoside monophosphate kinase activity 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.786785020466547 GO:0097001 ceramide binding 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.786785020466547 GO:0120227 acyl-CoA binding 1/788 19/18639 0.0526315789473684 1.24492385786802 0.56007069720714 0.786785020466547 GO:0001223 transcription coactivator binding 2/788 44/18639 0.0454545454545455 1.07516151361329 0.560497293341213 0.786785020466547 GO:0016248 channel inhibitor activity 2/788 44/18639 0.0454545454545455 1.07516151361329 0.560497293341213 0.786785020466547 GO:0019205 nucleobase-containing compound kinase activity 2/788 44/18639 0.0454545454545455 1.07516151361329 0.560497293341213 0.786785020466547 GO:0016279 protein-lysine N-methyltransferase activity 3/788 69/18639 0.0434782608695652 1.02841536084749 0.562930746392546 0.788975805796685 GO:0019903 protein phosphatase binding 6/788 144/18639 0.0416666666666667 0.985564720812183 0.572713303759767 0.797841340312233 GO:0016278 lysine N-methyltransferase activity 3/788 70/18639 0.0428571428571429 1.01372371283539 0.572760487020575 0.797841340312233 GO:0042605 peptide antigen binding 2/788 45/18639 0.0444444444444444 1.05126903553299 0.572786537458671 0.797841340312233 GO:0141110 transporter inhibitor activity 2/788 45/18639 0.0444444444444444 1.05126903553299 0.572786537458671 0.797841340312233 GO:0016408 C-acyltransferase activity 1/788 20/18639 0.05 1.18267766497462 0.578688543104067 0.80112472123442 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/788 20/18639 0.05 1.18267766497462 0.578688543104067 0.80112472123442 GO:0031418 L-ascorbic acid binding 1/788 20/18639 0.05 1.18267766497462 0.578688543104067 0.80112472123442 GO:0052745 inositol phosphate phosphatase activity 1/788 20/18639 0.05 1.18267766497462 0.578688543104067 0.80112472123442 GO:0141108 transporter regulator activity 7/788 170/18639 0.0411764705882353 0.973969841743804 0.582274969728403 0.803872084561663 GO:0140299 molecular sensor activity 3/788 71/18639 0.0422535211267606 0.999445914063058 0.582451565694568 0.803872084561663 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 5/788 122/18639 0.040983606557377 0.969407922110344 0.591631459338795 0.812249941507587 GO:0001846 opsonin binding 1/788 21/18639 0.0476190476190476 1.12635968092821 0.596519437783373 0.812249941507587 GO:0008373 sialyltransferase activity 1/788 21/18639 0.0476190476190476 1.12635968092821 0.596519437783373 0.812249941507587 GO:0010314 phosphatidylinositol-5-phosphate binding 1/788 21/18639 0.0476190476190476 1.12635968092821 0.596519437783373 0.812249941507587 GO:0035613 RNA stem-loop binding 1/788 21/18639 0.0476190476190476 1.12635968092821 0.596519437783373 0.812249941507587 GO:0036122 BMP binding 1/788 21/18639 0.0476190476190476 1.12635968092821 0.596519437783373 0.812249941507587 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/788 21/18639 0.0476190476190476 1.12635968092821 0.596519437783373 0.812249941507587 GO:0061891 calcium ion sensor activity 1/788 21/18639 0.0476190476190476 1.12635968092821 0.596519437783373 0.812249941507587 GO:0001784 phosphotyrosine residue binding 2/788 47/18639 0.0425531914893617 1.00653418295712 0.596608364116192 0.812249941507587 GO:0008970 phospholipase A1 activity 1/788 22/18639 0.0454545454545455 1.07516151361329 0.613596604129205 0.830376242713774 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/788 22/18639 0.0454545454545455 1.07516151361329 0.613596604129205 0.830376242713774 GO:0016881 acid-amino acid ligase activity 1/788 22/18639 0.0454545454545455 1.07516151361329 0.613596604129205 0.830376242713774 GO:0140784 metal ion sensor activity 1/788 22/18639 0.0454545454545455 1.07516151361329 0.613596604129205 0.830376242713774 GO:0001222 transcription corepressor binding 2/788 49/18639 0.0408163265306122 0.965451155081322 0.619419249440884 0.834508198948672 GO:0016763 pentosyltransferase activity 2/788 49/18639 0.0408163265306122 0.965451155081322 0.619419249440884 0.834508198948672 GO:0035254 glutamate receptor binding 2/788 49/18639 0.0408163265306122 0.965451155081322 0.619419249440884 0.834508198948672 GO:0042826 histone deacetylase binding 5/788 127/18639 0.0393700787401575 0.931242255885527 0.627263056369591 0.839935818876624 GO:0008171 O-methyltransferase activity 1/788 23/18639 0.0434782608695652 1.02841536084749 0.629951864157468 0.839935818876624 GO:0017134 fibroblast growth factor binding 1/788 23/18639 0.0434782608695652 1.02841536084749 0.629951864157468 0.839935818876624 GO:0031681 G-protein beta-subunit binding 1/788 23/18639 0.0434782608695652 1.02841536084749 0.629951864157468 0.839935818876624 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/788 23/18639 0.0434782608695652 1.02841536084749 0.629951864157468 0.839935818876624 GO:0070577 lysine-acetylated histone binding 1/788 23/18639 0.0434782608695652 1.02841536084749 0.629951864157468 0.839935818876624 GO:0099186 structural constituent of postsynapse 1/788 23/18639 0.0434782608695652 1.02841536084749 0.629951864157468 0.839935818876624 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.847077780846494 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.847077780846494 GO:0005540 hyaluronic acid binding 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.847077780846494 GO:0015295 solute:proton symporter activity 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.847077780846494 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.847077780846494 GO:0030552 cAMP binding 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.847077780846494 GO:0035035 histone acetyltransferase binding 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.847077780846494 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.847077780846494 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.847077780846494 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.847077780846494 GO:0050431 transforming growth factor beta binding 1/788 24/18639 0.0416666666666667 0.985564720812183 0.645615698012427 0.847077780846494 GO:0030159 signaling receptor complex adaptor activity 2/788 52/18639 0.0384615384615385 0.909752049980477 0.651750452843567 0.851026652944617 GO:0016835 carbon-oxygen lyase activity 3/788 79/18639 0.0379746835443038 0.898236201246546 0.654796516332146 0.851026652944617 GO:0001848 complement binding 1/788 25/18639 0.04 0.946142131979696 0.660617300481737 0.851026652944617 GO:0004709 MAP kinase kinase kinase activity 1/788 25/18639 0.04 0.946142131979696 0.660617300481737 0.851026652944617 GO:0015662 P-type ion transporter activity 1/788 25/18639 0.04 0.946142131979696 0.660617300481737 0.851026652944617 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/788 25/18639 0.04 0.946142131979696 0.660617300481737 0.851026652944617 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/788 25/18639 0.04 0.946142131979696 0.660617300481737 0.851026652944617 GO:0140358 P-type transmembrane transporter activity 1/788 25/18639 0.04 0.946142131979696 0.660617300481737 0.851026652944617 GO:0008013 beta-catenin binding 4/788 106/18639 0.0377358490566038 0.892586916961977 0.660695545542102 0.851026652944617 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 5/788 132/18639 0.0378787878787879 0.895967928011075 0.660954002704179 0.851026652944617 GO:0000049 tRNA binding 3/788 80/18639 0.0375 0.887008248730964 0.663176990867534 0.851026652944617 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/788 54/18639 0.037037037037037 0.876057529610829 0.672064689769593 0.851026652944617 GO:0051087 protein-folding chaperone binding 5/788 134/18639 0.0373134328358209 0.882595272369119 0.673864912563439 0.851026652944617 GO:0099106 ion channel regulator activity 6/788 160/18639 0.0375 0.887008248730964 0.67441357154168 0.851026652944617 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.851026652944617 GO:0004529 DNA exonuclease activity 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.851026652944617 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.851026652944617 GO:0008143 poly(A) binding 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.851026652944617 GO:0008157 protein phosphatase 1 binding 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.851026652944617 GO:0008198 ferrous iron binding 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.851026652944617 GO:0030247 polysaccharide binding 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.851026652944617 GO:0030507 spectrin binding 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.851026652944617 GO:0034237 protein kinase A regulatory subunit binding 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.851026652944617 GO:0043548 phosphatidylinositol 3-kinase binding 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.851026652944617 GO:0051139 metal cation:proton antiporter activity 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.851026652944617 GO:0070006 metalloaminopeptidase activity 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.851026652944617 GO:0070412 R-SMAD binding 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.851026652944617 GO:0120014 phospholipid transfer activity 1/788 26/18639 0.0384615384615385 0.909752049980477 0.674984635134171 0.851026652944617 GO:0004620 phospholipase activity 4/788 109/18639 0.036697247706422 0.868020304568528 0.682037276964254 0.858721028378392 GO:0002020 protease binding 5/788 136/18639 0.0367647058823529 0.869615930128397 0.686446297022598 0.861168762803092 GO:0004364 glutathione transferase activity 1/788 27/18639 0.037037037037037 0.876057529610829 0.688744486179906 0.861168762803092 GO:0005104 fibroblast growth factor receptor binding 1/788 27/18639 0.037037037037037 0.876057529610829 0.688744486179906 0.861168762803092 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/788 27/18639 0.037037037037037 0.876057529610829 0.688744486179906 0.861168762803092 GO:0035255 ionotropic glutamate receptor binding 1/788 27/18639 0.037037037037037 0.876057529610829 0.688744486179906 0.861168762803092 GO:0016504 peptidase activator activity 2/788 57/18639 0.0350877192982456 0.82994923857868 0.700720173005541 0.87401921124899 GO:0046625 sphingolipid binding 1/788 28/18639 0.0357142857142857 0.844769760696157 0.701922508149079 0.87401921124899 GO:0051019 mitogen-activated protein kinase binding 1/788 28/18639 0.0357142857142857 0.844769760696157 0.701922508149079 0.87401921124899 GO:0070851 growth factor receptor binding 5/788 139/18639 0.0359712230215827 0.850847240988935 0.704694671796457 0.876264076071523 GO:0016874 ligase activity 6/788 167/18639 0.0359281437125748 0.849828262257212 0.713666507641303 0.881237543282606 GO:0003785 actin monomer binding 1/788 29/18639 0.0344827586206897 0.815639768948013 0.714543273480255 0.881237543282606 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/788 29/18639 0.0344827586206897 0.815639768948013 0.714543273480255 0.881237543282606 GO:0035250 UDP-galactosyltransferase activity 1/788 29/18639 0.0344827586206897 0.815639768948013 0.714543273480255 0.881237543282606 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/788 29/18639 0.0344827586206897 0.815639768948013 0.714543273480255 0.881237543282606 GO:0097472 cyclin-dependent protein kinase activity 1/788 29/18639 0.0344827586206897 0.815639768948013 0.714543273480255 0.881237543282606 GO:0008081 phosphoric diester hydrolase activity 3/788 87/18639 0.0344827586206897 0.815639768948013 0.717691016953381 0.883913732051575 GO:0016247 channel regulator activity 6/788 168/18639 0.0357142857142857 0.844769760696157 0.718999501044552 0.884209791895589 GO:0033218 amide binding 9/788 247/18639 0.0364372469635627 0.861870363139399 0.721801036371289 0.884209791895589 GO:0035401 histone H3Y41 kinase activity 4/788 115/18639 0.0347826086956522 0.822732288677996 0.721843834534231 0.884209791895589 GO:0140801 histone H2AXY142 kinase activity 4/788 115/18639 0.0347826086956522 0.822732288677996 0.721843834534231 0.884209791895589 GO:0016769 transferase activity, transferring nitrogenous groups 1/788 30/18639 0.0333333333333333 0.788451776649746 0.726630318106669 0.887243282102315 GO:0098918 structural constituent of synapse 1/788 30/18639 0.0333333333333333 0.788451776649746 0.726630318106669 0.887243282102315 GO:0098531 ligand-modulated transcription factor activity 2/788 60/18639 0.0333333333333333 0.788451776649746 0.727264681457761 0.887243282102315 GO:0005126 cytokine receptor binding 10/788 275/18639 0.0363636363636364 0.860129210890632 0.730708362796484 0.889044899014834 GO:1901681 sulfur compound binding 10/788 275/18639 0.0363636363636364 0.860129210890632 0.730708362796484 0.889044899014834 GO:0016836 hydro-lyase activity 2/788 61/18639 0.0327868852459016 0.775526337688275 0.735658838540946 0.893357953617681 GO:0005164 tumor necrosis factor receptor binding 1/788 31/18639 0.032258064516129 0.763017848370722 0.738206185124345 0.893357953617681 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/788 31/18639 0.032258064516129 0.763017848370722 0.738206185124345 0.893357953617681 GO:0047499 calcium-independent phospholipase A2 activity 1/788 31/18639 0.032258064516129 0.763017848370722 0.738206185124345 0.893357953617681 GO:0008201 heparin binding 6/788 172/18639 0.0348837209302326 0.825123952307874 0.739639883791438 0.893597798248134 GO:0022804 active transmembrane transporter activity 17/788 457/18639 0.037199124726477 0.879891479412189 0.740381361601606 0.893597798248134 GO:0015106 bicarbonate transmembrane transporter activity 1/788 32/18639 0.03125 0.739173540609137 0.749292466622734 0.897625753296089 GO:0042910 xenobiotic transmembrane transporter activity 1/788 32/18639 0.03125 0.739173540609137 0.749292466622734 0.897625753296089 GO:0047498 calcium-dependent phospholipase A2 activity 1/788 32/18639 0.03125 0.739173540609137 0.749292466622734 0.897625753296089 GO:0070717 poly-purine tract binding 1/788 32/18639 0.03125 0.739173540609137 0.749292466622734 0.897625753296089 GO:0120015 sterol transfer activity 1/788 32/18639 0.03125 0.739173540609137 0.749292466622734 0.897625753296089 GO:0015085 calcium ion transmembrane transporter activity 5/788 147/18639 0.0340136054421769 0.804542629234435 0.749676375816977 0.897625753296089 GO:0019956 chemokine binding 1/788 33/18639 0.0303030303030303 0.71677434240886 0.759909843755065 0.906277702842452 GO:0140311 protein sequestering activity 1/788 33/18639 0.0303030303030303 0.71677434240886 0.759909843755065 0.906277702842452 GO:0140416 transcription regulator inhibitor activity 1/788 33/18639 0.0303030303030303 0.71677434240886 0.759909843755065 0.906277702842452 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 4/788 122/18639 0.0327868852459016 0.775526337688275 0.763470042561518 0.907627933651457 GO:0038024 cargo receptor activity 2/788 65/18639 0.0307692307692308 0.727801639984381 0.767060999157175 0.907627933651457 GO:0120013 lipid transfer activity 2/788 65/18639 0.0307692307692308 0.727801639984381 0.767060999157175 0.907627933651457 GO:0008175 tRNA methyltransferase activity 1/788 34/18639 0.0294117647058824 0.695692744102717 0.77007812512242 0.907627933651457 GO:0008376 acetylgalactosaminyltransferase activity 1/788 34/18639 0.0294117647058824 0.695692744102717 0.77007812512242 0.907627933651457 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/788 34/18639 0.0294117647058824 0.695692744102717 0.77007812512242 0.907627933651457 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/788 34/18639 0.0294117647058824 0.695692744102717 0.77007812512242 0.907627933651457 GO:0051427 hormone receptor binding 1/788 34/18639 0.0294117647058824 0.695692744102717 0.77007812512242 0.907627933651457 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/788 34/18639 0.0294117647058824 0.695692744102717 0.77007812512242 0.907627933651457 GO:0004896 cytokine receptor activity 3/788 96/18639 0.03125 0.739173540609137 0.777402964244699 0.915068072496364 GO:0004623 phospholipase A2 activity 1/788 35/18639 0.0285714285714286 0.675815808556925 0.77981628354239 0.916715110952302 GO:0016500 protein-hormone receptor activity 2/788 67/18639 0.0298507462686567 0.706076217895295 0.78151060543806 0.917513749761047 GO:0032934 sterol binding 2/788 68/18639 0.0294117647058824 0.695692744102717 0.78843624095292 0.922825095927581 GO:0004190 aspartic-type endopeptidase activity 1/788 36/18639 0.0277777777777778 0.657043147208122 0.789142491270222 0.922825095927581 GO:0042626 ATPase-coupled transmembrane transporter activity 3/788 98/18639 0.0306122448979592 0.724088366310991 0.789165724597731 0.922825095927581 GO:0004519 endonuclease activity 4/788 127/18639 0.031496062992126 0.744993804708422 0.790117947176933 0.922825095927581 GO:0030551 cyclic nucleotide binding 1/788 37/18639 0.027027027027027 0.639285224310605 0.798074153737516 0.92971525126123 GO:0070001 aspartic-type peptidase activity 1/788 37/18639 0.027027027027027 0.639285224310605 0.798074153737516 0.92971525126123 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 9/788 268/18639 0.0335820895522388 0.794335745132207 0.80376035201562 0.932247604434075 GO:0016298 lipase activity 4/788 130/18639 0.0307692307692308 0.727801639984381 0.804919276730866 0.932247604434075 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 4/788 130/18639 0.0307692307692308 0.727801639984381 0.804919276730866 0.932247604434075 GO:0000146 microfilament motor activity 1/788 38/18639 0.0263157894736842 0.62246192893401 0.806627941870772 0.932247604434075 GO:0005109 frizzled binding 1/788 38/18639 0.0263157894736842 0.62246192893401 0.806627941870772 0.932247604434075 GO:0042887 amide transmembrane transporter activity 1/788 38/18639 0.0263157894736842 0.62246192893401 0.806627941870772 0.932247604434075 GO:0005539 glycosaminoglycan binding 8/788 242/18639 0.0330578512396694 0.781935646264211 0.807466675079515 0.932247604434075 GO:0005262 calcium channel activity 4/788 131/18639 0.0305343511450382 0.722245902274577 0.809660792999461 0.933588465397338 GO:0008238 exopeptidase activity 3/788 102/18639 0.0294117647058824 0.695692744102717 0.811143066932985 0.934106156060405 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 17/788 484/18639 0.0351239669421488 0.830806624155724 0.816439066600844 0.939008799245755 GO:0004521 RNA endonuclease activity 2/788 73/18639 0.0273972602739726 0.648042556150476 0.820232791385427 0.942173371553273 GO:0004177 aminopeptidase activity 1/788 40/18639 0.025 0.59133883248731 0.822665090761183 0.942571916410785 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/788 40/18639 0.025 0.59133883248731 0.822665090761183 0.942571916410785 GO:0019838 growth factor binding 4/788 136/18639 0.0294117647058824 0.695692744102717 0.831973508938887 0.950826867358728 GO:0044325 transmembrane transporter binding 4/788 136/18639 0.0294117647058824 0.695692744102717 0.831973508938887 0.950826867358728 GO:0001216 DNA-binding transcription activator activity 17/788 491/18639 0.0346232179226069 0.818962130532323 0.833245057099207 0.951077691436468 GO:0001217 DNA-binding transcription repressor activity 9/788 278/18639 0.0323741007194245 0.765762516890041 0.83582356144298 0.952183495096577 GO:0019894 kinesin binding 1/788 42/18639 0.0238095238095238 0.563179840464104 0.837373759515242 0.952183495096577 GO:0051879 Hsp90 protein binding 1/788 42/18639 0.0238095238095238 0.563179840464104 0.837373759515242 0.952183495096577 GO:0005496 steroid binding 3/788 108/18639 0.0277777777777778 0.657043147208122 0.840456009490716 0.954487729371365 GO:0004857 enzyme inhibitor activity 14/788 416/18639 0.0336538461538462 0.796033043732917 0.843683352594571 0.955213045721781 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/788 43/18639 0.0232558139534884 0.550082634871916 0.844264627800556 0.955213045721781 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/788 43/18639 0.0232558139534884 0.550082634871916 0.844264627800556 0.955213045721781 GO:0019199 transmembrane receptor protein kinase activity 2/788 78/18639 0.0256410256410256 0.606501366653651 0.847676726465384 0.957288601660061 GO:0004713 protein tyrosine kinase activity 4/788 140/18639 0.0285714285714286 0.675815808556925 0.848217002134634 0.957288601660061 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/788 44/18639 0.0227272727272727 0.537580756806645 0.85086386813682 0.959078474807588 GO:0016829 lyase activity 6/788 200/18639 0.03 0.709606598984772 0.854099789040908 0.961527035234098 GO:0051539 4 iron, 4 sulfur cluster binding 1/788 45/18639 0.0222222222222222 0.525634517766497 0.857183807470414 0.963007979949089 GO:0048306 calcium-dependent protein binding 2/788 80/18639 0.025 0.59133883248731 0.857545822852894 0.963007979949089 GO:0001618 virus receptor activity 2/788 81/18639 0.0246913580246914 0.584038353073886 0.862258152877872 0.963414286550663 GO:0004180 carboxypeptidase activity 1/788 46/18639 0.0217391304347826 0.514207680423747 0.863236252329687 0.963414286550663 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/788 46/18639 0.0217391304347826 0.514207680423747 0.863236252329687 0.963414286550663 GO:0030276 clathrin binding 1/788 46/18639 0.0217391304347826 0.514207680423747 0.863236252329687 0.963414286550663 GO:0030291 protein serine/threonine kinase inhibitor activity 1/788 46/18639 0.0217391304347826 0.514207680423747 0.863236252329687 0.963414286550663 GO:0140272 exogenous protein binding 2/788 82/18639 0.024390243902439 0.576915934133961 0.86682730759923 0.964058312845847 GO:0140359 ABC-type transporter activity 1/788 47/18639 0.0212765957446809 0.503267091478561 0.869032510769111 0.964058312845847 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/788 48/18639 0.0208333333333333 0.492782360406091 0.874583413389267 0.964058312845847 GO:0005004 GPI-linked ephrin receptor activity 1/788 49/18639 0.0204081632653061 0.482725577540661 0.879899333471525 0.964058312845847 GO:0005008 hepatocyte growth factor receptor activity 1/788 49/18639 0.0204081632653061 0.482725577540661 0.879899333471525 0.964058312845847 GO:0005009 insulin receptor activity 1/788 49/18639 0.0204081632653061 0.482725577540661 0.879899333471525 0.964058312845847 GO:0005011 macrophage colony-stimulating factor receptor activity 1/788 49/18639 0.0204081632653061 0.482725577540661 0.879899333471525 0.964058312845847 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/788 49/18639 0.0204081632653061 0.482725577540661 0.879899333471525 0.964058312845847 GO:0005020 stem cell factor receptor activity 1/788 49/18639 0.0204081632653061 0.482725577540661 0.879899333471525 0.964058312845847 GO:0008288 boss receptor activity 1/788 49/18639 0.0204081632653061 0.482725577540661 0.879899333471525 0.964058312845847 GO:0036332 placental growth factor receptor activity 1/788 49/18639 0.0204081632653061 0.482725577540661 0.879899333471525 0.964058312845847 GO:0038062 protein tyrosine kinase collagen receptor activity 1/788 49/18639 0.0204081632653061 0.482725577540661 0.879899333471525 0.964058312845847 GO:0060175 brain-derived neurotrophic factor receptor activity 1/788 49/18639 0.0204081632653061 0.482725577540661 0.879899333471525 0.964058312845847 GO:0005006 epidermal growth factor receptor activity 1/788 50/18639 0.02 0.473071065989848 0.884990206264663 0.964058312845847 GO:0005007 fibroblast growth factor receptor activity 1/788 50/18639 0.02 0.473071065989848 0.884990206264663 0.964058312845847 GO:0005017 platelet-derived growth factor receptor activity 1/788 50/18639 0.02 0.473071065989848 0.884990206264663 0.964058312845847 GO:0005019 platelet-derived growth factor beta-receptor activity 1/788 50/18639 0.02 0.473071065989848 0.884990206264663 0.964058312845847 GO:0015605 organophosphate ester transmembrane transporter activity 1/788 50/18639 0.02 0.473071065989848 0.884990206264663 0.964058312845847 GO:0001664 G protein-coupled receptor binding 9/788 297/18639 0.0303030303030303 0.71677434240886 0.885350091580938 0.964058312845847 GO:0005010 insulin-like growth factor receptor activity 1/788 51/18639 0.0196078431372549 0.463795162735145 0.889865547459103 0.964058312845847 GO:0005021 vascular endothelial growth factor receptor activity 1/788 51/18639 0.0196078431372549 0.463795162735145 0.889865547459103 0.964058312845847 GO:0005030 neurotrophin receptor activity 1/788 51/18639 0.0196078431372549 0.463795162735145 0.889865547459103 0.964058312845847 GO:0016597 amino acid binding 1/788 51/18639 0.0196078431372549 0.463795162735145 0.889865547459103 0.964058312845847 GO:0030544 Hsp70 protein binding 1/788 51/18639 0.0196078431372549 0.463795162735145 0.889865547459103 0.964058312845847 GO:0008237 metallopeptidase activity 5/788 184/18639 0.0271739130434783 0.642759600529684 0.893313425280519 0.964058312845847 GO:0005080 protein kinase C binding 1/788 52/18639 0.0192307692307692 0.454876024990238 0.894534470882937 0.964058312845847 GO:0004864 protein phosphatase inhibitor activity 1/788 53/18639 0.0188679245283019 0.446293458480988 0.899005705452488 0.964058312845847 GO:0005003 ephrin receptor activity 1/788 53/18639 0.0188679245283019 0.446293458480988 0.899005705452488 0.964058312845847 GO:0005005 transmembrane-ephrin receptor activity 1/788 53/18639 0.0188679245283019 0.446293458480988 0.899005705452488 0.964058312845847 GO:0005544 calcium-dependent phospholipid binding 1/788 53/18639 0.0188679245283019 0.446293458480988 0.899005705452488 0.964058312845847 GO:0038064 collagen receptor activity 1/788 53/18639 0.0188679245283019 0.446293458480988 0.899005705452488 0.964058312845847 GO:0051018 protein kinase A binding 1/788 53/18639 0.0188679245283019 0.446293458480988 0.899005705452488 0.964058312845847 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/788 53/18639 0.0188679245283019 0.446293458480988 0.899005705452488 0.964058312845847 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/788 91/18639 0.021978021978022 0.519858314274558 0.902092950909366 0.966222781542733 GO:0015485 cholesterol binding 1/788 54/18639 0.0185185185185185 0.438028764805415 0.903287611408769 0.966357397294115 GO:0043178 alcohol binding 2/788 92/18639 0.0217391304347826 0.514207680423747 0.905422509279598 0.967310057861295 GO:0008374 O-acyltransferase activity 1/788 55/18639 0.0181818181818182 0.430064605445316 0.907388195869888 0.967310057861295 GO:0098632 cell-cell adhesion mediator activity 1/788 55/18639 0.0181818181818182 0.430064605445316 0.907388195869888 0.967310057861295 GO:0030246 carbohydrate binding 8/788 280/18639 0.0285714285714286 0.675815808556925 0.909637740551914 0.968055808938293 GO:0019212 phosphatase inhibitor activity 1/788 56/18639 0.0178571428571429 0.422384880348078 0.911315127728181 0.968055808938293 GO:0030170 pyridoxal phosphate binding 1/788 56/18639 0.0178571428571429 0.422384880348078 0.911315127728181 0.968055808938293 GO:0005178 integrin binding 4/788 161/18639 0.0248447204968944 0.587665920484283 0.913221627486561 0.968055808938293 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/788 57/18639 0.0175438596491228 0.41497461928934 0.915075751919657 0.968055808938293 GO:0070279 vitamin B6 binding 1/788 57/18639 0.0175438596491228 0.41497461928934 0.915075751919657 0.968055808938293 GO:0008083 growth factor activity 4/788 162/18639 0.0246913580246914 0.584038353073886 0.915583757347611 0.968055808938293 GO:0001786 phosphatidylserine binding 1/788 59/18639 0.0169491525423729 0.400907683042244 0.922125918697523 0.971563905014639 GO:0004879 nuclear receptor activity 1/788 59/18639 0.0169491525423729 0.400907683042244 0.922125918697523 0.971563905014639 GO:0015459 potassium channel regulator activity 1/788 59/18639 0.0169491525423729 0.400907683042244 0.922125918697523 0.971563905014639 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/788 60/18639 0.0166666666666667 0.394225888324873 0.925428651532095 0.973615105109108 GO:0004175 endopeptidase activity 12/788 405/18639 0.0296296296296296 0.700846023688663 0.926226759285213 0.973615105109108 GO:0015297 antiporter activity 3/788 135/18639 0.0222222222222222 0.525634517766497 0.928586347752852 0.97496174026548 GO:1901682 sulfur compound transmembrane transporter activity 1/788 63/18639 0.0158730158730159 0.37545322697607 0.934520860269704 0.980054359261963 GO:0140101 catalytic activity, acting on a tRNA 3/788 139/18639 0.0215827338129496 0.510508344593361 0.936941396421102 0.98145425534725 GO:0005516 calmodulin binding 5/788 207/18639 0.0241545893719807 0.571341867137497 0.940923737605093 0.983359220957249 GO:0004497 monooxygenase activity 2/788 106/18639 0.0188679245283019 0.446293458480988 0.942179046381668 0.983359220957249 GO:0008235 metalloexopeptidase activity 1/788 66/18639 0.0151515151515152 0.35838717120443 0.942505723563014 0.983359220957249 GO:0004252 serine-type endopeptidase activity 4/788 176/18639 0.0227272727272727 0.537580756806645 0.943111111249928 0.983359220957249 GO:0003777 microtubule motor activity 1/788 68/18639 0.0147058823529412 0.347846372051359 0.947280995811943 0.98543385525201 GO:0005548 phospholipid transporter activity 1/788 68/18639 0.0147058823529412 0.347846372051359 0.947280995811943 0.98543385525201 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/788 70/18639 0.0142857142857143 0.337907904278463 0.951660112103639 0.986583418969827 GO:0016782 transferase activity, transferring sulphur-containing groups 1/788 70/18639 0.0142857142857143 0.337907904278463 0.951660112103639 0.986583418969827 GO:0097110 scaffold protein binding 1/788 70/18639 0.0142857142857143 0.337907904278463 0.951660112103639 0.986583418969827 GO:0019842 vitamin binding 3/788 150/18639 0.02 0.473071065989848 0.955482471123154 0.98941140194196 GO:0048029 monosaccharide binding 1/788 74/18639 0.0135135135135135 0.319642612155303 0.959358466914197 0.991432081815666 GO:0015294 solute:monoatomic cation symporter activity 2/788 116/18639 0.0172413793103448 0.407819884474007 0.959627291580429 0.991432081815666 GO:0098631 cell adhesion mediator activity 1/788 76/18639 0.0131578947368421 0.311230964467005 0.962735432695455 0.992966586996364 GO:0140375 immune receptor activity 3/788 156/18639 0.0192307692307692 0.454876024990238 0.963309399110411 0.992966586996364 GO:0008236 serine-type peptidase activity 4/788 194/18639 0.0206185567010309 0.487702129886441 0.966449963807241 0.995069211027046 GO:0003730 mRNA 3'-UTR binding 6/788 262/18639 0.0229007633587786 0.541684426705933 0.96777873562088 0.995303728101565 GO:0017171 serine hydrolase activity 4/788 198/18639 0.0202020202020202 0.477849561605907 0.970249424466353 0.996710772406344 GO:0005201 extracellular matrix structural constituent 3/788 168/18639 0.0178571428571429 0.422384880348078 0.97524077948419 0.999999408753233 GO:0003823 antigen binding 3/788 174/18639 0.0172413793103448 0.407819884474007 0.979722953463698 0.999999408753233 GO:0072341 modified amino acid binding 1/788 91/18639 0.010989010989011 0.259929157137279 0.980563914887852 0.999999408753233 GO:0042562 hormone binding 1/788 94/18639 0.0106382978723404 0.251633545739281 0.982937475110588 0.999999408753233 GO:0015291 secondary active transmembrane transporter activity 6/788 287/18639 0.0209059233449477 0.494499372114823 0.983647742677572 0.999999408753233 GO:0061135 endopeptidase regulator activity 3/788 184/18639 0.016304347826087 0.385655760317811 0.985523722384758 0.999999408753233 GO:0015293 symporter activity 2/788 146/18639 0.0136986301369863 0.324021278075238 0.986664381004668 0.999999408753233 GO:0031406 carboxylic acid binding 3/788 187/18639 0.0160427807486631 0.379468769510573 0.98692806530489 0.999999408753233 GO:0043177 organic acid binding 3/788 189/18639 0.0158730158730159 0.37545322697607 0.987790609506732 0.999999408753233 GO:0004222 metalloendopeptidase activity 1/788 110/18639 0.00909090909090909 0.215032302722658 0.991484647493897 0.999999408753233 GO:0005319 lipid transporter activity 2/788 178/18639 0.0112359550561798 0.265770261792049 0.996059487210955 0.999999408753233 GO:0061134 peptidase regulator activity 3/788 226/18639 0.0132743362831858 0.313985220789722 0.996648656675952 0.999999408753233 GO:0046873 metal ion transmembrane transporter activity 9/788 450/18639 0.02 0.473071065989848 0.996976902029517 0.999999408753233 GO:0005125 cytokine activity 3/788 234/18639 0.0128205128205128 0.303250683326825 0.997482639815727 0.999999408753233 GO:0004866 endopeptidase inhibitor activity 1/788 161/18639 0.0062111801242236 0.146916480121071 0.999074652964353 0.999999408753233 GO:0015081 sodium ion transmembrane transporter activity 1/788 164/18639 0.00609756097560976 0.14422898353349 0.999188067160453 0.999999408753233 GO:0008514 organic anion transmembrane transporter activity 3/788 269/18639 0.0111524163568773 0.263794274715528 0.999296376296027 0.999999408753233 GO:0030414 peptidase inhibitor activity 1/788 169/18639 0.00591715976331361 0.13996185384315 0.999347082549251 0.999999408753233 GO:0045182 translation regulator activity 5/788 356/18639 0.0140449438202247 0.332212827240062 0.999367816885315 0.999999408753233 GO:0046943 carboxylic acid transmembrane transporter activity 1/788 188/18639 0.00531914893617021 0.12581677286964 0.999714960996405 0.999999408753233 GO:0005342 organic acid transmembrane transporter activity 1/788 189/18639 0.00529100529100529 0.12515107565869 0.99972713436017 0.999999408753233 GO:0005261 monoatomic cation channel activity 4/788 341/18639 0.0117302052785924 0.277461035771172 0.999746102045601 0.999999408753233 GO:0005216 monoatomic ion channel activity 4/788 448/18639 0.00892857142857143 0.211192440174039 0.999995038962927 0.999999408753233 GO:0030371 translation repressor activity 1/788 329/18639 0.00303951367781155 0.0718952987826516 0.999999408753233 0.999999408753233