category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	6/50	233/9376	4.82884120171674	ITGA2/MYL4/MYOZ3/ITGA10/TNNC2/TMOD2	4.3333512190758
NA	NA	hsa04518	Integrin signaling	4/50	154/9376	4.87064935064935	ITGA2/ITGA10/KDR/SRC	3.54612929112178
Metabolism	Glycan biosynthesis and metabolism	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	2/50	28/9376	13.3942857142857	FUT1/ST3GAL6	4.80910325666384
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	3/50	99/9376	5.68242424242424	ITGA2/PRKAB2/ITGA10	3.42931606049133
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	4/50	184/9376	4.07652173913043	EFNA1/ABLIM3/SRC/SEMA3C	3.08593537338977
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	2/50	42/9376	8.92952380952381	ALDH8A1/AFMID	3.771036962253
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	4/50	203/9376	3.69497536945813	ITGA2/ITGA10/KDR/SRC	2.84230093118825
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	4/50	204/9376	3.67686274509804	ITGA2/NANOG/KDR/SRC	2.83029757328117
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	4/50	212/9376	3.53811320754717	EFNA1/F2RL3/KDR/SRC	2.73690242292693
Organismal Systems	Immune system	hsa04611	Platelet activation	3/50	126/9376	4.4647619047619	ITGA2/F2RL3/SRC	2.86688806503551
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	3/50	140/9376	4.01828571428571	MYL4/PRKAB2/PLAT	2.63454328726929
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	3/50	142/9376	3.96169014084507	PLAT/KDR/SRC	2.60382499437419
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	2/50	60/9376	6.25066666666667	KDR/SRC	2.98743364976374
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/50	71/9376	5.28225352112676	ATP6V0C/SRC	2.65195588637471
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	2/50	80/9376	4.688	KDR/SRC	2.42555308078445
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	2/50	86/9376	4.36093023255814	ITGA2/ITGA10	2.29257631196851
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	2/50	88/9376	4.26181818181818	PLAT/F2RL3	2.25093480628257
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	2/50	89/9376	4.21393258426966	ITGA2/ITGA10	2.23057575863356
Metabolism	Glycan biosynthesis and metabolism	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	1/50	16/9376	11.72	FUT1	3.14224314252814
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	2/50	90/9376	4.16711111111111	KL/PRKAB2	2.21051338905585
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	3/50	193/9376	2.91481865284974	PPBP/CX3CL1/SRC	1.96805371013436
Cellular Processes	Cell motility	hsa04814	Motor proteins	3/50	194/9376	2.89979381443299	MYL4/TNNC2/TUBE1	1.95776979978859
Metabolism	Metabolism of other amino acids	hsa00450	Selenocompound metabolism	1/50	17/9376	11.0305882352941	CTH	3.03081253288229
Metabolism	Metabolism of cofactors and vitamins	hsa00785	Lipoic acid metabolism	1/50	19/9376	9.86947368421053	BCKDHA	2.83353949278032
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	2/50	100/9376	3.7504	PPBP/CX3CL1	2.02459623165503
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/50	100/9376	3.7504	ITGA2/CD8B2	2.02459623165503
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	2/50	105/9376	3.57180952380952	ITGA2/ITGA10	1.9404081678433
Metabolism	Glycan biosynthesis and metabolism	hsa00515	Mannose type O-glycan biosynthesis	1/50	23/9376	8.15304347826087	FKRP	2.51479304433147
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	3/50	232/9376	2.4248275862069	ITGA2/ITGA10/SRC	1.60901885565935
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	4/50	362/9376	2.07204419889503	ITGA2/EFNA1/ITGA10/KDR	1.52310952581506
Human Diseases	Endocrine and metabolic disease	hsa04950	Maturity onset diabetes of the young	1/50	26/9376	7.21230769230769	MAFA	2.32250555448804
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	1/50	28/9376	6.69714285714286	ATP6V0C	2.21054677127425
Metabolism	Carbohydrate metabolism	hsa00053	Ascorbate and aldarate metabolism	1/50	31/9376	6.04903225806452	KL	2.06168482472676
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/50	31/9376	6.04903225806452	AFMID	2.06168482472676
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/50	32/9376	5.86	BCKDHA	2.01635862994795
Metabolism	Global and overview maps	hsa01210	2-Oxocarboxylic acid metabolism	1/50	33/9376	5.68242424242424	BCKDHA	1.97291098040047
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/50	34/9376	5.51529411764706	PRKAB2	1.9312055752829
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/50	138/9376	2.71768115942029	CD8B2/SRC	1.488387627206
Metabolism	Carbohydrate metabolism	hsa00040	Pentose and glucuronate interconversions	1/50	36/9376	5.20888888888889	KL	1.8525426188448
Genetic Information Processing	Replication and repair	hsa03030	DNA replication	1/50	36/9376	5.20888888888889	RNASEH2A	1.8525426188448
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	2/50	144/9376	2.60444444444444	LPIN3/PRKAB2	1.42062995140826
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/50	38/9376	4.93473684210526	SCNN1A	1.77952252683274
Human Diseases	Immune disease	hsa05340	Primary immunodeficiency	1/50	38/9376	4.93473684210526	CD8B2	1.77952252683274
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	1/50	39/9376	4.80820512820513	CTH	1.74490542320874
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	1/50	41/9376	4.57365853658537	CTH	1.679077551316
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/50	41/9376	4.57365853658537	SRC	1.679077551316
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/50	154/9376	2.43532467532468	PRKAB2/SRC	1.31498526793309
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	2/50	155/9376	2.41961290322581	ITGA2/ATP6V0C	1.30487740486203
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/50	160/9376	2.344	CD8B2/NRXN2	1.25548336232942
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/50	44/9376	4.26181818181818	PTPRN2	1.58789454665268
NA	NA	hsa04517	IgSF CAM signaling	3/50	299/9376	1.88147157190635	SCN8A/KDR/SRC	1.13421574500384
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/50	47/9376	3.98978723404255	MAFA	1.50450834311264
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	1/50	48/9376	3.90666666666667	BCKDHA	1.47823852016503
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	2/50	170/9376	2.20611764705882	PRKAB2/SRC	1.16198783666786
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/50	50/9376	3.7504	KLRC4-KLRK1	1.42776289344425
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/50	51/9376	3.67686274509804	ATP6V0C	1.40349123945021
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/50	52/9376	3.60615384615385	STAR	1.37982345659873
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/50	52/9376	3.60615384615385	STAR	1.37982345659873
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/50	53/9376	3.53811320754717	KL	1.35673183790022
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/50	181/9376	2.07204419889503	ATP6V0C/SRC	1.06634821558492
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/50	54/9376	3.47259259259259	CTH	1.33419045484856
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	2/50	183/9376	2.04939890710382	PWP2/GNL3L	1.04968854332158
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/50	55/9376	3.40945454545455	CERS3	1.31217501241418
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/50	56/9376	3.34857142857143	EVC2	1.29066271826976
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	3/50	333/9376	1.68936936936937	ITGA2/ITGA10/ATP6V0C	0.937865949967447
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/50	62/9376	3.02451612903226	PRKAB2	1.17104046924699
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/50	201/9376	1.86587064676617	PLAT/SIX4	0.908596258817796
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/50	65/9376	2.88492307692308	LPIN3	1.11654204396532
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/50	65/9376	2.88492307692308	STAR	1.11654204396532
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/50	70/9376	2.67885714285714	PRKAB2	1.03229583116653
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/50	70/9376	2.67885714285714	EGLN2	1.03229583116653
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/50	71/9376	2.64112676056338	SRC	1.01633304788969
NA	NA	hsa04382	Cornified envelope formation	2/50	217/9376	1.72829493087558	KRT1/CERS3	0.794760106671074
NA	NA	hsa04081	Hormone signaling	2/50	219/9376	1.71251141552511	HCRTR2/SRC	0.781196361651654
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/50	75/9376	2.50026666666667	CTH	0.955118384059166
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/50	78/9376	2.40410256410256	SRC	0.911746904844426
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	2/50	227/9376	1.65215859030837	CX3CL1/SRC	0.72828651539179
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/50	79/9376	2.37367088607595	ATP6V0C	0.89773417608777
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/50	82/9376	2.28682926829268	CD8B2	0.856938109513278
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/50	83/9376	2.25927710843374	FOXK1	0.843733554814713
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	2/50	238/9376	1.57579831932773	EFNA1/KDR	0.658804003043301
NA	NA	hsa04519	Cadherin signaling	3/50	404/9376	1.39247524752475	KRT1/PCDHGA2/KDR	0.590447457625284
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/50	86/9376	2.18046511627907	SRC	0.805225391610308
Organismal Systems	Sensory system	hsa04742	Taste transduction	1/50	86/9376	2.18046511627907	SCNN1A	0.805225391610308
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	1/50	87/9376	2.15540229885057	MYL4	0.792740975914337
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/50	89/9376	2.10696629213483	SRC	0.768271303805687
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	1/50	89/9376	2.10696629213483	SRC	0.768271303805687
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/50	93/9376	2.01634408602151	SRC	0.721208768506997
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/50	93/9376	2.01634408602151	SRC	0.721208768506997
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/50	93/9376	2.01634408602151	ITGA2	0.721208768506997
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/50	254/9376	1.47653543307087	TNNC2/KDR	0.563754416970086
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/50	95/9376	1.97389473684211	ATP6V0C	0.698553012573337
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/50	98/9376	1.9134693877551	STAR	0.665583866675145
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/50	99/9376	1.89414141414141	SRC	0.654851707814938
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/50	99/9376	1.89414141414141	SRC	0.654851707814938
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/50	104/9376	1.80307692307692	LPIN3	0.602989902100653
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/50	105/9376	1.78590476190476	SRC	0.592958383981741
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/50	105/9376	1.78590476190476	SRC	0.592958383981741
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/50	106/9376	1.76905660377358	PLAT	0.583034569811309
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/50	107/9376	1.75252336448598	PRKAB2	0.573216088276081
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/50	109/9376	1.72036697247706	PRKAB2	0.553886009157147
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/50	110/9376	1.70472727272727	EGLN2	0.544370031252178
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/50	115/9376	1.63060869565217	KL	0.498199018907261
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/50	117/9376	1.60273504273504	BICRA	0.480352732470294
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/50	119/9376	1.57579831932773	CX3CL1	0.462840843660798
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/50	298/9376	1.25852348993289	PPBP/CX3CL1	0.332074851941664
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	2/50	300/9376	1.25013333333333	EFNA1/KDR	0.322409543896637
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/50	122/9376	1.53704918032787	PRKAB2	0.437171820995782
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/50	122/9376	1.53704918032787	CD8B2	0.437171820995782
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/50	122/9376	1.53704918032787	SRC	0.437171820995782
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/50	125/9376	1.50016	CERS3	0.412185354996759
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/50	130/9376	1.44246153846154	SRC	0.371957389866265
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/50	133/9376	1.40992481203008	PRKAB2	0.348615333309693
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/50	133/9376	1.40992481203008	KLRC4-KLRK1	0.348615333309693
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	1/50	138/9376	1.35884057971015	ATP6V0C	0.310938893432506
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/50	138/9376	1.35884057971015	PRKAB2	0.310938893432506
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/50	139/9376	1.34906474820144	SRC	0.303578391165923
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/50	144/9376	1.30222222222222	NANOG	0.267597885583827
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/50	154/9376	1.21766233766234	AFMID	0.19941325633875
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/50	154/9376	1.21766233766234	MYL4	0.19941325633875
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/50	155/9376	1.2098064516129	STAR	0.192849541929254
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	1/50	157/9376	1.1943949044586	CX3CL1	0.179852189980698
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	1/50	157/9376	1.1943949044586	PRKAB2	0.179852189980698
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/50	158/9376	1.18683544303797	LPIN3	0.173417288956897
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/50	163/9376	1.15042944785276	SRC	0.141856442020992
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	2/50	370/9376	1.01362162162162	HCRTR2/F2RL3	0.0195743179286014
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/50	180/9376	1.04177777777778	SRC	0.0414385968676452
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/50	195/9376	0.961641025641026	SRC	-0.039633482395984
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/50	196/9376	0.956734693877551	SRC	-0.044819748042384
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/50	200/9376	0.9376	SRC	-0.0653124266237277
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	1/50	205/9376	0.914731707317073	SRC	-0.0903814045004737
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/50	216/9376	0.868148148148148	SRC	-0.14354507857768
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/50	217/9376	0.864147465437788	SRC	-0.148250619746034
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	1/50	227/9376	0.826079295154185	SRC	-0.194222856171763
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	1/50	235/9376	0.797957446808511	PRKAB2	-0.229669253859775
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/50	248/9376	0.756129032258064	RHOJ	-0.284984382764367
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	1/50	250/9376	0.75008	ATP6V0C	-0.293260600227318
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/50	250/9376	0.75008	SRC	-0.293260600227318
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	1/50	253/9376	0.741185770750988	SRC	-0.305564225839888
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/50	323/9376	0.580557275541796	EFNA1	-0.561695056215565
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/50	449/9376	0.417639198218263	OR7A17	-0.925945601939699