category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/10	75/9376	25.0026666666667	IGFBP3/PTEN	6.81920686050066
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	2/10	93/9376	20.1634408602151	COL4A1/PTEN	6.06847198412035
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	3/10	333/9376	8.44684684684685	COL4A1/ISG15/PTEN	4.52112833545822
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/10	101/9376	18.5663366336634	COL4A1/COL3A1	5.79953922814107
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	2/10	103/9376	18.2058252427184	COL4A1/COL3A1	5.73710173812424
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/10	103/9376	18.2058252427184	COL4A1/COL3A1	5.73710173812424
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	2/10	106/9376	17.6905660377358	HSP90B1/PTEN	5.64667370324763
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	3/10	362/9376	7.77016574585635	COL4A1/HSP90B1/PTEN	4.29243147751682
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/10	130/9376	14.4246153846154	COL4A1/COL3A1	5.03622523817308
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	2/10	144/9376	13.0222222222222	KLF4/IL6ST	4.75036150532495
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	2/10	157/9376	11.943949044586	IGFBP3/PTEN	4.51846104534447
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	2/10	203/9376	9.23743842364532	COL4A1/PTEN	3.87697557418615
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	2/10	205/9376	9.14731707317073	COL3A1/PTEN	3.85382299340162
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	2/10	217/9376	8.64147465437788	KLF4/HSP90B1	3.72127337662034
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	2/10	233/9376	8.0480686695279	COL4A1/COL3A1	3.5596909042807
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	2/10	238/9376	7.87899159663865	ISG15/IL6ST	3.51233751236694
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	2/10	323/9376	5.80557275541796	TIMP3/PTEN	2.87182994222476
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/10	59/9376	15.8915254237288	PTEN	3.74917495174595
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/10	71/9376	13.2056338028169	PTEN	3.37318284588198
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/10	72/9376	13.0222222222222	ISG15	3.34599055079187
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/10	73/9376	12.8438356164384	PTEN	3.31933321804545
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/10	75/9376	12.5013333333333	HSP90B1	3.26755240410392
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/10	76/9376	12.3368421052632	PTEN	3.24239545040033
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/10	78/9376	12.0205128205128	PTEN	3.19347040700531
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/10	80/9376	11.72	PTEN	3.14630110498824
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/10	89/9376	10.5348314606742	COL4A1	2.95310482242529
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/10	90/9376	10.4177777777778	PTEN	2.93335020347351
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	1/10	94/9376	9.97446808510638	HSP90B1	2.85733014932406
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/10	98/9376	9.56734693877551	PTEN	2.78574121391131
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/10	100/9376	9.376	IL6ST	2.75147049555261
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/10	109/9376	8.60183486238532	IL6ST	2.60837878921144
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/10	109/9376	8.60183486238532	PTEN	2.60837878921144
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/10	122/9376	7.68524590163935	IGFBP3	2.42851681946341
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/10	125/9376	7.5008	PTEN	2.39076028338829
Organismal Systems	Immune system	hsa04611	Platelet activation	1/10	126/9376	7.44126984126984	COL3A1	2.37845238142504
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/10	133/9376	7.04962406015038	PTEN	2.29591757590535
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/10	139/9376	6.7453237410072	HSP90B1	2.22979529838407
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	1/10	142/9376	6.60281690140845	HSP90B1	2.19818494246432
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/10	148/9376	6.33513513513514	PTEN	2.1376226891942
NA	NA	hsa04518	Integrin signaling	1/10	154/9376	6.08831168831169	COL4A1	2.08031964112582
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/10	156/9376	6.01025641025641	IFIT1	2.06188933600354
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/10	158/9376	5.93417721518987	PTEN	2.04377694878079
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/10	168/9376	5.58095238095238	IL6ST	1.95765575000644
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/10	169/9376	5.54792899408284	PTEN	1.94942493912398
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/10	170/9376	5.51529411764706	PTEN	1.94125944417248
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/10	174/9376	5.38850574712644	HSP90B1	1.9092321660556
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/10	196/9376	4.78367346938775	IL6ST	1.74915745877875
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/10	201/9376	4.66467661691542	IGFBP3	1.71608664216728
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	1/10	204/9376	4.59607843137255	TIMP3	1.69676140639628
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	1/10	205/9376	4.57365853658537	ISG15	1.69040278108372
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	1/10	205/9376	4.57365853658537	IL6ST	1.69040278108372
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/10	216/9376	4.34074074074074	HSP90B1	1.62304467301524
NA	NA	hsa04382	Cornified envelope formation	1/10	217/9376	4.32073732718894	COL4A1	1.61714485296865
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	1/10	224/9376	4.18571428571429	PTEN	1.57681734287187
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	1/10	227/9376	4.13039647577093	PTEN	1.56003385125904
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/10	248/9376	3.78064516129032	HSP90B1	1.45008065284978
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/10	298/9376	3.14630872483221	IL6ST	1.23030785076557