ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0045296 cadherin binding 18/234 334/18639 0.0538922155688623 4.29272224781207 2.4479173332622e-07 0.00013855212106264 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 21/234 484/18639 0.0433884297520661 3.45605530832804 8.70297752264671e-07 0.000206710378853687 GO:0001216 DNA-binding transcription activator activity 21/234 491/18639 0.0427698574338086 3.40678364405452 1.09563805046124e-06 0.000206710378853687 GO:0140662 ATP-dependent protein folding chaperone 6/234 40/18639 0.15 11.9480769230769 9.86214386839333e-06 0.00139549335737766 GO:0140297 DNA-binding transcription factor binding 19/234 488/18639 0.0389344262295082 3.10127679697352 1.37962107177266e-05 0.00156173105324665 GO:0051082 unfolded protein binding 9/234 121/18639 0.0743801652892562 5.92466624284806 2.21707647243043e-05 0.00187572274727276 GO:0097718 disordered domain specific binding 5/234 28/18639 0.178571428571429 14.2239010989011 2.3197984506907e-05 0.00187572274727276 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 15/234 349/18639 0.0429799426934097 3.42351774300198 3.72320546998117e-05 0.00244415340928759 GO:0031072 heat shock protein binding 9/234 131/18639 0.0687022900763359 5.47240164415737 4.1633130175123e-05 0.00244415340928759 GO:0044183 protein folding chaperone 7/234 75/18639 0.0933333333333333 7.43435897435897 4.31829224255758e-05 0.00244415340928759 GO:0044389 ubiquitin-like protein ligase binding 14/234 322/18639 0.0434782608695652 3.46321070234114 5.98376976399296e-05 0.0030789215331091 GO:0031625 ubiquitin protein ligase binding 13/234 302/18639 0.043046357615894 3.42880794701987 0.000121219210923343 0.00571750611521766 GO:0051087 protein-folding chaperone binding 8/234 134/18639 0.0597014925373134 4.75545350172216 0.000293617402410248 0.0127836499818615 GO:0001671 ATPase activator activity 4/234 27/18639 0.148148148148148 11.8005698005698 0.000338605461471994 0.0128509890224154 GO:0003725 double-stranded RNA binding 6/234 75/18639 0.08 6.37230769230769 0.000358975372592777 0.0128509890224154 GO:0060590 ATPase regulator activity 5/234 49/18639 0.102040816326531 8.12794348508634 0.00036327884162305 0.0128509890224154 GO:0008187 poly-pyrimidine tract binding 4/234 30/18639 0.133333333333333 10.6205128205128 0.000513378146894622 0.0161428906190198 GO:0035925 mRNA 3'-UTR AU-rich region binding 4/234 30/18639 0.133333333333333 10.6205128205128 0.000513378146894622 0.0161428906190198 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 11/234 268/18639 0.041044776119403 3.26937428243398 0.000598730738974176 0.0178358735925991 GO:0071889 14-3-3 protein binding 4/234 33/18639 0.121212121212121 9.65501165501166 0.000744302289679053 0.0210637547979172 GO:0001217 DNA-binding transcription repressor activity 11/234 278/18639 0.039568345323741 3.15177089097952 0.000809501733670779 0.0218179991075077 GO:0019207 kinase regulator activity 11/234 287/18639 0.0383275261324042 3.05293487000804 0.00104866331276286 0.0264044450709215 GO:0042826 histone deacetylase binding 7/234 127/18639 0.0551181102362205 4.39036947304664 0.00112174192550352 0.0264044450709215 GO:0003714 transcription corepressor activity 9/234 204/18639 0.0441176470588235 3.51414027149321 0.00112956678110122 0.0264044450709215 GO:1990226 histone methyltransferase binding 3/234 17/18639 0.176470588235294 14.0565610859729 0.00116627407557074 0.0264044450709215 GO:0019887 protein kinase regulator activity 10/234 255/18639 0.0392156862745098 3.1236802413273 0.00148296428191403 0.032282991675513 GO:0046332 SMAD binding 5/234 79/18639 0.0632911392405063 5.04138266796495 0.0031683722409396 0.0664184699396967 GO:0001221 transcription coregulator binding 6/234 115/18639 0.0521739130434783 4.15585284280936 0.00331451267391265 0.0670005061940914 GO:0070412 R-SMAD binding 3/234 26/18639 0.115384615384615 9.19082840236686 0.0041034693134997 0.0778590693621756 GO:0004860 protein kinase inhibitor activity 5/234 84/18639 0.0595238095238095 4.74130036630037 0.00412680579658174 0.0778590693621756 GO:0008266 poly(U) RNA binding 3/234 27/18639 0.111111111111111 8.85042735042735 0.00457407729500316 0.0835137983539287 GO:0051015 actin filament binding 8/234 209/18639 0.0382775119617225 3.04895104895105 0.0050018322791043 0.0884699084366573 GO:0003727 single-stranded RNA binding 5/234 89/18639 0.0561797752808989 4.47493517718237 0.00527631118160633 0.0904967311754297 GO:0019210 kinase inhibitor activity 5/234 90/18639 0.0555555555555556 4.42521367521368 0.00553081095023936 0.0920717352304553 GO:0070888 E-box binding 4/234 59/18639 0.0677966101694915 5.40026075619296 0.00642287249989628 0.101094188089308 GO:0008140 cAMP response element binding protein binding 2/234 10/18639 0.2 15.9307692307692 0.00660863067014909 0.101094188089308 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/234 10/18639 0.2 15.9307692307692 0.00660863067014909 0.101094188089308 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 2/234 11/18639 0.181818181818182 14.4825174825175 0.00801072629469995 0.114251010117984 GO:0140311 protein sequestering activity 3/234 33/18639 0.0909090909090909 7.24125874125874 0.00807427633342642 0.114251010117984 GO:0140416 transcription regulator inhibitor activity 3/234 33/18639 0.0909090909090909 7.24125874125874 0.00807427633342642 0.114251010117984 GO:1990841 promoter-specific chromatin binding 4/234 68/18639 0.0588235294117647 4.68552036199095 0.0105332399549711 0.145410093036918 GO:0004535 poly(A)-specific ribonuclease activity 2/234 13/18639 0.153846153846154 12.2544378698225 0.0111746883365664 0.150592228535633 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 3/234 38/18639 0.0789473684210526 6.28846153846154 0.0119255590520725 0.156973637755187 GO:0034236 protein kinase A catalytic subunit binding 2/234 14/18639 0.142857142857143 11.3791208791209 0.0129301510894399 0.166328761741431 GO:0043539 protein serine/threonine kinase activator activity 4/234 73/18639 0.0547945205479452 4.36459430979979 0.0134141169298148 0.168719781828337 GO:0004532 RNA exonuclease activity 3/234 40/18639 0.075 5.97403846153846 0.0137139406710841 0.168741096083339 GO:0048029 monosaccharide binding 4/234 74/18639 0.0540540540540541 4.30561330561331 0.0140445343439889 0.169132051887185 GO:0048487 beta-tubulin binding 3/234 42/18639 0.0714285714285714 5.68956043956044 0.0156466258011143 0.182562058596056 GO:0004857 enzyme inhibitor activity 11/234 416/18639 0.0264423076923077 2.10623150887574 0.0163689289585287 0.182562058596056 GO:0048156 tau protein binding 3/234 43/18639 0.0697674418604651 5.55724508050089 0.0166674743803639 0.182562058596056 GO:0005159 insulin-like growth factor receptor binding 2/234 16/18639 0.125 9.95673076923077 0.0167724859487543 0.182562058596056 GO:0070411 I-SMAD binding 2/234 16/18639 0.125 9.95673076923077 0.0167724859487543 0.182562058596056 GO:0003697 single-stranded DNA binding 5/234 121/18639 0.0413223140495868 3.2914812460267 0.0183496676101507 0.194337166890943 GO:0046982 protein heterodimerization activity 10/234 369/18639 0.02710027100271 2.1586408171774 0.0185410017881819 0.194337166890943 GO:0030276 clathrin binding 3/234 46/18639 0.0652173913043478 5.19481605351171 0.0199493505937698 0.201630936358459 GO:0030291 protein serine/threonine kinase inhibitor activity 3/234 46/18639 0.0652173913043478 5.19481605351171 0.0199493505937698 0.201630936358459 GO:0004527 exonuclease activity 4/234 84/18639 0.0476190476190476 3.79304029304029 0.0213914308865693 0.208750860031004 GO:0051117 ATPase binding 4/234 84/18639 0.0476190476190476 3.79304029304029 0.0213914308865693 0.208750860031004 GO:0003779 actin binding 11/234 443/18639 0.0248306997742664 1.97786073971176 0.0246657242210114 0.234610528198206 GO:0000339 RNA cap binding 2/234 20/18639 0.1 7.96538461538462 0.0256993864810755 0.234610528198206 GO:0031418 L-ascorbic acid binding 2/234 20/18639 0.1 7.96538461538462 0.0256993864810755 0.234610528198206 GO:0061608 nuclear import signal receptor activity 2/234 20/18639 0.1 7.96538461538462 0.0256993864810755 0.234610528198206 GO:0030544 Hsp70 protein binding 3/234 51/18639 0.0588235294117647 4.68552036199095 0.0261531335217635 0.234963072592352 GO:0005080 protein kinase C binding 3/234 52/18639 0.0576923076923077 4.59541420118343 0.0275039624112798 0.243238167574756 GO:0070182 DNA polymerase binding 2/234 21/18639 0.0952380952380952 7.58608058608059 0.0281731951694971 0.245323514860544 GO:0044325 transmembrane transporter binding 5/234 136/18639 0.0367647058823529 2.92845022624434 0.0286306050247243 0.245529127939302 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/234 22/18639 0.0909090909090909 7.24125874125874 0.0307383267020239 0.256927872493314 GO:0140767 enzyme-substrate adaptor activity 5/234 139/18639 0.0359712230215827 2.86524626452684 0.0310479275922897 0.256927872493314 GO:0098632 cell-cell adhesion mediator activity 3/234 55/18639 0.0545454545454545 4.34475524475524 0.0317755319338021 0.256927872493314 GO:0140313 molecular sequestering activity 3/234 55/18639 0.0545454545454545 4.34475524475524 0.0317755319338021 0.256927872493314 GO:0008408 3'-5' exonuclease activity 3/234 58/18639 0.0517241379310345 4.12002652519894 0.0363734261856722 0.289962805930852 GO:0070063 RNA polymerase binding 3/234 59/18639 0.0508474576271186 4.05019556714472 0.0379779201331245 0.296156793216489 GO:0008139 nuclear localization sequence binding 2/234 25/18639 0.08 6.37230769230769 0.038955298330969 0.296156793216489 GO:0019209 kinase activator activity 5/234 148/18639 0.0337837837837838 2.69100831600832 0.0390523755274796 0.296156793216489 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3/234 60/18639 0.05 3.98269230769231 0.0396180639465688 0.296156793216489 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 2/234 26/18639 0.0769230769230769 6.12721893491124 0.0418596174157581 0.296156793216489 GO:0034237 protein kinase A regulatory subunit binding 2/234 26/18639 0.0769230769230769 6.12721893491124 0.0418596174157581 0.296156793216489 GO:0043548 phosphatidylinositol 3-kinase binding 2/234 26/18639 0.0769230769230769 6.12721893491124 0.0418596174157581 0.296156793216489 GO:0050750 low-density lipoprotein particle receptor binding 2/234 26/18639 0.0769230769230769 6.12721893491124 0.0418596174157581 0.296156793216489 GO:0052742 phosphatidylinositol kinase activity 2/234 26/18639 0.0769230769230769 6.12721893491124 0.0418596174157581 0.296156793216489 GO:0023026 MHC class II protein complex binding 2/234 27/18639 0.0740740740740741 5.9002849002849 0.0448424606254186 0.309522350170572 GO:0035255 ionotropic glutamate receptor binding 2/234 27/18639 0.0740740740740741 5.9002849002849 0.0448424606254186 0.309522350170572 GO:0003712 transcription coregulator activity 11/234 495/18639 0.0222222222222222 1.77008547008547 0.0486135017482896 0.328049636058343 GO:0004518 nuclease activity 6/234 209/18639 0.0287081339712919 2.28671328671329 0.0486858117118389 0.328049636058343 GO:0032934 sterol binding 3/234 68/18639 0.0441176470588235 3.51414027149321 0.0539973961251008 0.352860434134316 GO:0033612 receptor serine/threonine kinase binding 2/234 30/18639 0.0666666666666667 5.31025641025641 0.0542382646107518 0.352860434134316 GO:0070566 adenylyltransferase activity 2/234 30/18639 0.0666666666666667 5.31025641025641 0.0542382646107518 0.352860434134316 GO:0005096 GTPase activator activity 7/234 271/18639 0.025830258302583 2.05747942094806 0.0554824287327131 0.3558070923726 GO:0002039 p53 binding 3/234 69/18639 0.0434782608695652 3.46321070234114 0.0559484650550555 0.3558070923726 GO:0017124 SH3 domain binding 4/234 115/18639 0.0347826086956522 2.77056856187291 0.0570472632289968 0.356412539077071 GO:0070325 lipoprotein particle receptor binding 2/234 31/18639 0.0645161290322581 5.13895781637717 0.0575115691877985 0.356412539077071 GO:0097110 scaffold protein binding 3/234 70/18639 0.0428571428571429 3.41373626373626 0.0579327802033402 0.356412539077071 GO:1990782 protein tyrosine kinase binding 4/234 117/18639 0.0341880341880342 2.72320841551611 0.0600310632558144 0.359561509300057 GO:0043425 bHLH transcription factor binding 2/234 32/18639 0.0625 4.97836538461539 0.0608518127965369 0.359561509300057 GO:0140142 nucleocytoplasmic carrier activity 2/234 32/18639 0.0625 4.97836538461539 0.0608518127965369 0.359561509300057 GO:0005201 extracellular matrix structural constituent 5/234 168/18639 0.0297619047619048 2.37065018315018 0.060985697690469 0.359561509300057 GO:0004540 RNA nuclease activity 4/234 121/18639 0.0330578512396694 2.63318499682136 0.0662427169316809 0.386529667869396 GO:0098631 cell adhesion mediator activity 3/234 76/18639 0.0394736842105263 3.14423076923077 0.0705197568157442 0.407287575078686 GO:0000175 3'-5'-RNA exonuclease activity 2/234 35/18639 0.0571428571428571 4.55164835164835 0.0712525930650973 0.40736330984692 GO:0000993 RNA polymerase II complex binding 2/234 36/18639 0.0555555555555556 4.42521367521368 0.0748392239533378 0.414522569225243 GO:0023023 MHC protein complex binding 2/234 37/18639 0.0540540540540541 4.30561330561331 0.0784823227741475 0.414522569225243 GO:0001618 virus receptor activity 3/234 81/18639 0.037037037037037 2.95014245014245 0.0818646432908982 0.414522569225243 GO:0030971 receptor tyrosine kinase binding 3/234 81/18639 0.037037037037037 2.95014245014245 0.0818646432908982 0.414522569225243 GO:0033192 calmodulin-dependent protein phosphatase activity 3/234 81/18639 0.037037037037037 2.95014245014245 0.0818646432908982 0.414522569225243 GO:0140791 histone H2AXS140 phosphatase activity 3/234 81/18639 0.037037037037037 2.95014245014245 0.0818646432908982 0.414522569225243 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 3/234 81/18639 0.037037037037037 2.95014245014245 0.0818646432908982 0.414522569225243 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 3/234 81/18639 0.037037037037037 2.95014245014245 0.0818646432908982 0.414522569225243 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 3/234 81/18639 0.037037037037037 2.95014245014245 0.0818646432908982 0.414522569225243 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 3/234 81/18639 0.037037037037037 2.95014245014245 0.0818646432908982 0.414522569225243 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 3/234 81/18639 0.037037037037037 2.95014245014245 0.0818646432908982 0.414522569225243 GO:1990439 MAP kinase serine/threonine phosphatase activity 3/234 81/18639 0.037037037037037 2.95014245014245 0.0818646432908982 0.414522569225243 GO:1901981 phosphatidylinositol phosphate binding 5/234 185/18639 0.027027027027027 2.15280665280665 0.0841493079154487 0.414522569225243 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 3/234 82/18639 0.0365853658536585 2.91416510318949 0.0842227834998286 0.414522569225243 GO:0033549 MAP kinase phosphatase activity 3/234 82/18639 0.0365853658536585 2.91416510318949 0.0842227834998286 0.414522569225243 GO:0140272 exogenous protein binding 3/234 82/18639 0.0365853658536585 2.91416510318949 0.0842227834998286 0.414522569225243 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 3/234 83/18639 0.036144578313253 2.8790546802595 0.0866097889104865 0.42259603899427 GO:0017018 myosin phosphatase activity 3/234 84/18639 0.0357142857142857 2.84478021978022 0.0890252836521131 0.426787492418348 GO:0030331 nuclear estrogen receptor binding 2/234 40/18639 0.05 3.98269230769231 0.0897309392186985 0.426787492418348 GO:0071949 FAD binding 2/234 40/18639 0.05 3.98269230769231 0.0897309392186985 0.426787492418348 GO:0002020 protease binding 4/234 136/18639 0.0294117647058824 2.34276018099548 0.0923478564576089 0.431240858349333 GO:0001727 lipid kinase activity 2/234 41/18639 0.0487804878048781 3.88555347091932 0.0935806201701807 0.431240858349333 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 2/234 41/18639 0.0487804878048781 3.88555347091932 0.0935806201701807 0.431240858349333 GO:0016922 nuclear receptor binding 4/234 137/18639 0.0291970802919708 2.32565974171814 0.0942403442605348 0.431240858349333 GO:0042277 peptide binding 6/234 249/18639 0.0240963855421687 1.91936978683967 0.0944767958221153 0.431240858349333 GO:0004520 DNA endonuclease activity 2/234 42/18639 0.0476190476190476 3.79304029304029 0.097477319888634 0.433698088764215 GO:0008307 structural constituent of muscle 2/234 42/18639 0.0476190476190476 3.79304029304029 0.097477319888634 0.433698088764215 GO:0043175 RNA polymerase core enzyme binding 2/234 42/18639 0.0476190476190476 3.79304029304029 0.097477319888634 0.433698088764215 GO:0030295 protein kinase activator activity 4/234 139/18639 0.0287769784172662 2.29219701162147 0.098080133148091 0.433698088764215 GO:0001046 core promoter sequence-specific DNA binding 2/234 44/18639 0.0454545454545455 3.62062937062937 0.105404713225025 0.444931322973103 GO:0001223 transcription coactivator binding 2/234 44/18639 0.0454545454545455 3.62062937062937 0.105404713225025 0.444931322973103 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/234 44/18639 0.0454545454545455 3.62062937062937 0.105404713225025 0.444931322973103 GO:0043014 alpha-tubulin binding 2/234 44/18639 0.0454545454545455 3.62062937062937 0.105404713225025 0.444931322973103 GO:0019903 protein phosphatase binding 4/234 144/18639 0.0277777777777778 2.21260683760684 0.107992775163054 0.444931322973103 GO:0015631 tubulin binding 8/234 385/18639 0.0207792207792208 1.65514485514486 0.113012947784692 0.444931322973103 GO:0004867 serine-type endopeptidase inhibitor activity 3/234 95/18639 0.0315789473684211 2.51538461538462 0.117364986055841 0.444931322973103 GO:0005381 iron ion transmembrane transporter activity 1/234 10/18639 0.1 7.96538461538462 0.118710087278552 0.444931322973103 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/234 10/18639 0.1 7.96538461538462 0.118710087278552 0.444931322973103 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/234 10/18639 0.1 7.96538461538462 0.118710087278552 0.444931322973103 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/234 10/18639 0.1 7.96538461538462 0.118710087278552 0.444931322973103 GO:0019911 structural constituent of myelin sheath 1/234 10/18639 0.1 7.96538461538462 0.118710087278552 0.444931322973103 GO:0030957 Tat protein binding 1/234 10/18639 0.1 7.96538461538462 0.118710087278552 0.444931322973103 GO:0031434 mitogen-activated protein kinase kinase binding 1/234 10/18639 0.1 7.96538461538462 0.118710087278552 0.444931322973103 GO:0032052 bile acid binding 1/234 10/18639 0.1 7.96538461538462 0.118710087278552 0.444931322973103 GO:0042975 peroxisome proliferator activated receptor binding 1/234 10/18639 0.1 7.96538461538462 0.118710087278552 0.444931322973103 GO:0050815 phosphoserine residue binding 1/234 10/18639 0.1 7.96538461538462 0.118710087278552 0.444931322973103 GO:0051880 G-quadruplex DNA binding 1/234 10/18639 0.1 7.96538461538462 0.118710087278552 0.444931322973103 GO:0070513 death domain binding 1/234 10/18639 0.1 7.96538461538462 0.118710087278552 0.444931322973103 GO:0001222 transcription corepressor binding 2/234 49/18639 0.0408163265306122 3.25117739403454 0.125926218169042 0.444931322973103 GO:0035254 glutamate receptor binding 2/234 49/18639 0.0408163265306122 3.25117739403454 0.125926218169042 0.444931322973103 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/234 11/18639 0.0909090909090909 7.24125874125874 0.129780023376938 0.444931322973103 GO:0005536 D-glucose binding 1/234 11/18639 0.0909090909090909 7.24125874125874 0.129780023376938 0.444931322973103 GO:0008432 JUN kinase binding 1/234 11/18639 0.0909090909090909 7.24125874125874 0.129780023376938 0.444931322973103 GO:0015173 aromatic amino acid transmembrane transporter activity 1/234 11/18639 0.0909090909090909 7.24125874125874 0.129780023376938 0.444931322973103 GO:0032050 clathrin heavy chain binding 1/234 11/18639 0.0909090909090909 7.24125874125874 0.129780023376938 0.444931322973103 GO:0034056 estrogen response element binding 1/234 11/18639 0.0909090909090909 7.24125874125874 0.129780023376938 0.444931322973103 GO:0043522 leucine zipper domain binding 1/234 11/18639 0.0909090909090909 7.24125874125874 0.129780023376938 0.444931322973103 GO:0045294 alpha-catenin binding 1/234 11/18639 0.0909090909090909 7.24125874125874 0.129780023376938 0.444931322973103 GO:0050998 nitric-oxide synthase binding 1/234 11/18639 0.0909090909090909 7.24125874125874 0.129780023376938 0.444931322973103 GO:0070697 activin receptor binding 1/234 11/18639 0.0909090909090909 7.24125874125874 0.129780023376938 0.444931322973103 GO:0140031 phosphorylation-dependent protein binding 1/234 11/18639 0.0909090909090909 7.24125874125874 0.129780023376938 0.444931322973103 GO:0140537 transcription regulator activator activity 1/234 11/18639 0.0909090909090909 7.24125874125874 0.129780023376938 0.444931322973103 GO:0180030 inositol phosphate kinase activity 1/234 11/18639 0.0909090909090909 7.24125874125874 0.129780023376938 0.444931322973103 GO:0003743 translation initiation factor activity 2/234 51/18639 0.0392156862745098 3.1236802413273 0.134382475755939 0.444931322973103 GO:0005048 signal sequence binding 2/234 51/18639 0.0392156862745098 3.1236802413273 0.134382475755939 0.444931322973103 GO:0016830 carbon-carbon lyase activity 2/234 51/18639 0.0392156862745098 3.1236802413273 0.134382475755939 0.444931322973103 GO:0004722 protein serine/threonine phosphatase activity 3/234 103/18639 0.029126213592233 2.32001493651979 0.139809684962242 0.444931322973103 GO:0000340 RNA 7-methylguanosine cap binding 1/234 12/18639 0.0833333333333333 6.63782051282051 0.140711496134603 0.444931322973103 GO:0004859 phospholipase inhibitor activity 1/234 12/18639 0.0833333333333333 6.63782051282051 0.140711496134603 0.444931322973103 GO:0005095 GTPase inhibitor activity 1/234 12/18639 0.0833333333333333 6.63782051282051 0.140711496134603 0.444931322973103 GO:0005165 neurotrophin receptor binding 1/234 12/18639 0.0833333333333333 6.63782051282051 0.140711496134603 0.444931322973103 GO:0016208 AMP binding 1/234 12/18639 0.0833333333333333 6.63782051282051 0.140711496134603 0.444931322973103 GO:0016840 carbon-nitrogen lyase activity 1/234 12/18639 0.0833333333333333 6.63782051282051 0.140711496134603 0.444931322973103 GO:0031543 peptidyl-proline dioxygenase activity 1/234 12/18639 0.0833333333333333 6.63782051282051 0.140711496134603 0.444931322973103 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/234 12/18639 0.0833333333333333 6.63782051282051 0.140711496134603 0.444931322973103 GO:0035197 siRNA binding 1/234 12/18639 0.0833333333333333 6.63782051282051 0.140711496134603 0.444931322973103 GO:0035497 cAMP response element binding 1/234 12/18639 0.0833333333333333 6.63782051282051 0.140711496134603 0.444931322973103 GO:0043047 single-stranded telomeric DNA binding 1/234 12/18639 0.0833333333333333 6.63782051282051 0.140711496134603 0.444931322973103 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/234 12/18639 0.0833333333333333 6.63782051282051 0.140711496134603 0.444931322973103 GO:0097677 STAT family protein binding 1/234 12/18639 0.0833333333333333 6.63782051282051 0.140711496134603 0.444931322973103 GO:0051018 protein kinase A binding 2/234 53/18639 0.0377358490566038 3.00580551523948 0.142962175172729 0.44953661748758 GO:0015485 cholesterol binding 2/234 54/18639 0.037037037037037 2.95014245014245 0.147294749016718 0.451329085508734 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/234 54/18639 0.037037037037037 2.95014245014245 0.147294749016718 0.451329085508734 GO:0035091 phosphatidylinositol binding 6/234 284/18639 0.0211267605633803 1.68282773564464 0.148402675525517 0.451329085508734 GO:0005172 vascular endothelial growth factor receptor binding 1/234 13/18639 0.0769230769230769 6.12721893491124 0.151506230117773 0.451329085508734 GO:0008035 high-density lipoprotein particle binding 1/234 13/18639 0.0769230769230769 6.12721893491124 0.151506230117773 0.451329085508734 GO:0043560 insulin receptor substrate binding 1/234 13/18639 0.0769230769230769 6.12721893491124 0.151506230117773 0.451329085508734 GO:0071837 HMG box domain binding 1/234 13/18639 0.0769230769230769 6.12721893491124 0.151506230117773 0.451329085508734 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/234 13/18639 0.0769230769230769 6.12721893491124 0.151506230117773 0.451329085508734 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/234 13/18639 0.0769230769230769 6.12721893491124 0.151506230117773 0.451329085508734 GO:0140852 histone ubiquitin ligase activity 1/234 13/18639 0.0769230769230769 6.12721893491124 0.151506230117773 0.451329085508734 GO:0005496 steroid binding 3/234 108/18639 0.0277777777777778 2.21260683760684 0.154515286031699 0.457882994209119 GO:0061134 peptidase regulator activity 5/234 226/18639 0.0221238938053097 1.76225323349217 0.155868343857464 0.45948688866315 GO:0016504 peptidase activator activity 2/234 57/18639 0.0350877192982456 2.79487179487179 0.160446978066336 0.463565229967603 GO:0004705 JUN kinase activity 1/234 14/18639 0.0714285714285714 5.68956043956044 0.162165928504568 0.463565229967603 GO:0005545 1-phosphatidylinositol binding 1/234 14/18639 0.0714285714285714 5.68956043956044 0.162165928504568 0.463565229967603 GO:0044548 S100 protein binding 1/234 14/18639 0.0714285714285714 5.68956043956044 0.162165928504568 0.463565229967603 GO:0070742 C2H2 zinc finger domain binding 1/234 14/18639 0.0714285714285714 5.68956043956044 0.162165928504568 0.463565229967603 GO:0098847 sequence-specific single stranded DNA binding 1/234 14/18639 0.0714285714285714 5.68956043956044 0.162165928504568 0.463565229967603 GO:0030695 GTPase regulator activity 9/234 489/18639 0.0184049079754601 1.466021708353 0.163469374374186 0.464943044702459 GO:0060589 nucleoside-triphosphatase regulator activity 9/234 490/18639 0.0183673469387755 1.46302982731554 0.164832583803967 0.465951645731578 GO:0045309 protein phosphorylated amino acid binding 2/234 59/18639 0.0338983050847458 2.70013037809648 0.169330816916724 0.465951645731578 GO:0008201 heparin binding 4/234 172/18639 0.0232558139534884 1.85241502683363 0.17090802534575 0.465951645731578 GO:0000774 adenyl-nucleotide exchange factor activity 1/234 15/18639 0.0666666666666667 5.31025641025641 0.172692273349128 0.465951645731578 GO:0031386 protein tag activity 1/234 15/18639 0.0666666666666667 5.31025641025641 0.172692273349128 0.465951645731578 GO:0042809 nuclear vitamin D receptor binding 1/234 15/18639 0.0666666666666667 5.31025641025641 0.172692273349128 0.465951645731578 GO:0045504 dynein heavy chain binding 1/234 15/18639 0.0666666666666667 5.31025641025641 0.172692273349128 0.465951645731578 GO:0140776 protein-containing complex destabilizing activity 1/234 15/18639 0.0666666666666667 5.31025641025641 0.172692273349128 0.465951645731578 GO:0141047 molecular tag activity 1/234 15/18639 0.0666666666666667 5.31025641025641 0.172692273349128 0.465951645731578 GO:0001098 basal transcription machinery binding 2/234 60/18639 0.0333333333333333 2.65512820512821 0.173803670467419 0.465951645731578 GO:0001099 basal RNA polymerase II transcription machinery binding 2/234 60/18639 0.0333333333333333 2.65512820512821 0.173803670467419 0.465951645731578 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/234 60/18639 0.0333333333333333 2.65512820512821 0.173803670467419 0.465951645731578 GO:0005543 phospholipid binding 9/234 497/18639 0.0181086519114688 1.44242377340969 0.174526058118542 0.465951645731578 GO:0003735 structural constituent of ribosome 4/234 175/18639 0.0228571428571429 1.82065934065934 0.178296135530723 0.469398039175728 GO:0003688 DNA replication origin binding 1/234 16/18639 0.0625 4.97836538461539 0.183086925842486 0.469398039175728 GO:0004707 MAP kinase activity 1/234 16/18639 0.0625 4.97836538461539 0.183086925842486 0.469398039175728 GO:0008142 oxysterol binding 1/234 16/18639 0.0625 4.97836538461539 0.183086925842486 0.469398039175728 GO:0016722 oxidoreductase activity, acting on metal ions 1/234 16/18639 0.0625 4.97836538461539 0.183086925842486 0.469398039175728 GO:0030275 LRR domain binding 1/234 16/18639 0.0625 4.97836538461539 0.183086925842486 0.469398039175728 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/234 16/18639 0.0625 4.97836538461539 0.183086925842486 0.469398039175728 GO:0055102 lipase inhibitor activity 1/234 16/18639 0.0625 4.97836538461539 0.183086925842486 0.469398039175728 GO:0043021 ribonucleoprotein complex binding 4/234 177/18639 0.0225988700564972 1.80008691873099 0.183280859819498 0.469398039175728 GO:0005507 copper ion binding 2/234 63/18639 0.0317460317460317 2.52869352869353 0.187331621648588 0.477611251590543 GO:0005539 glycosaminoglycan binding 5/234 242/18639 0.0206611570247934 1.64574062301335 0.189055747232944 0.47984552885133 GO:0004536 DNA nuclease activity 2/234 64/18639 0.03125 2.48918269230769 0.191873571636335 0.480071549728149 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/234 17/18639 0.0588235294117647 4.68552036199095 0.193351526570234 0.480071549728149 GO:0031489 myosin V binding 1/234 17/18639 0.0588235294117647 4.68552036199095 0.193351526570234 0.480071549728149 GO:0051787 misfolded protein binding 1/234 17/18639 0.0588235294117647 4.68552036199095 0.193351526570234 0.480071549728149 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/234 181/18639 0.0220994475138122 1.76030599235019 0.193385712611339 0.480071549728149 GO:0019843 rRNA binding 2/234 65/18639 0.0307692307692308 2.4508875739645 0.196429987088079 0.481851990992076 GO:0120013 lipid transfer activity 2/234 65/18639 0.0307692307692308 2.4508875739645 0.196429987088079 0.481851990992076 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/234 122/18639 0.0245901639344262 1.95870113493064 0.197972609304967 0.481851990992076 GO:0061135 endopeptidase regulator activity 4/234 184/18639 0.0217391304347826 1.73160535117057 0.201076713863691 0.481851990992076 GO:0008409 5'-3' exonuclease activity 1/234 18/18639 0.0555555555555556 4.42521367521368 0.203487695767021 0.481851990992076 GO:0031690 adrenergic receptor binding 1/234 18/18639 0.0555555555555556 4.42521367521368 0.203487695767021 0.481851990992076 GO:0034185 apolipoprotein binding 1/234 18/18639 0.0555555555555556 4.42521367521368 0.203487695767021 0.481851990992076 GO:0035615 clathrin adaptor activity 1/234 18/18639 0.0555555555555556 4.42521367521368 0.203487695767021 0.481851990992076 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/234 18/18639 0.0555555555555556 4.42521367521368 0.203487695767021 0.481851990992076 GO:0070064 proline-rich region binding 1/234 18/18639 0.0555555555555556 4.42521367521368 0.203487695767021 0.481851990992076 GO:0098641 cadherin binding involved in cell-cell adhesion 1/234 18/18639 0.0555555555555556 4.42521367521368 0.203487695767021 0.481851990992076 GO:0140104 molecular carrier activity 5/234 249/18639 0.0200803212851406 1.59947482236639 0.204318865438336 0.481851990992076 GO:0031406 carboxylic acid binding 4/234 187/18639 0.0213903743315508 1.70382558617853 0.20885818371199 0.490513410709486 GO:0043177 organic acid binding 4/234 189/18639 0.0211640211640212 1.68579568579569 0.214093492195384 0.498814291214434 GO:0004519 endonuclease activity 3/234 127/18639 0.0236220472440945 1.88158691701999 0.214155252235172 0.498814291214434 GO:0019902 phosphatase binding 4/234 190/18639 0.0210526315789474 1.67692307692308 0.216724860700292 0.500256085143022 GO:0031490 chromatin DNA binding 3/234 128/18639 0.0234375 1.86688701923077 0.217425789655801 0.500256085143022 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 3/234 128/18639 0.0234375 1.86688701923077 0.217425789655801 0.500256085143022 GO:0030742 GTP-dependent protein binding 1/234 20/18639 0.05 3.98269230769231 0.2233811202567 0.511877384879726 GO:0005518 collagen binding 2/234 72/18639 0.0277777777777778 2.21260683760684 0.228642822036852 0.518692317808562 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/234 21/18639 0.0476190476190476 3.79304029304029 0.23314151651106 0.518692317808562 GO:0005123 death receptor binding 1/234 21/18639 0.0476190476190476 3.79304029304029 0.23314151651106 0.518692317808562 GO:0019200 carbohydrate kinase activity 1/234 21/18639 0.0476190476190476 3.79304029304029 0.23314151651106 0.518692317808562 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/234 21/18639 0.0476190476190476 3.79304029304029 0.23314151651106 0.518692317808562 GO:0072542 protein phosphatase activator activity 1/234 21/18639 0.0476190476190476 3.79304029304029 0.23314151651106 0.518692317808562 GO:0140312 cargo adaptor activity 1/234 21/18639 0.0476190476190476 3.79304029304029 0.23314151651106 0.518692317808562 GO:0003730 mRNA 3'-UTR binding 5/234 262/18639 0.0190839694656489 1.52011156782149 0.233686468270642 0.518692317808562 GO:0003684 damaged DNA binding 2/234 74/18639 0.027027027027027 2.15280665280665 0.237919494799892 0.526025133034135 GO:0019003 GDP binding 2/234 75/18639 0.0266666666666667 2.12410256410256 0.242565441547077 0.530553460320349 GO:0061133 endopeptidase activator activity 1/234 22/18639 0.0454545454545455 3.62062937062937 0.242779763644824 0.530553460320349 GO:0070034 telomerase RNA binding 1/234 22/18639 0.0454545454545455 3.62062937062937 0.242779763644824 0.530553460320349 GO:0140789 histone phosphatase activity 3/234 136/18639 0.0220588235294118 1.75707013574661 0.24393531021318 0.53102840607946 GO:0005158 insulin receptor binding 1/234 23/18639 0.0434782608695652 3.46321070234114 0.252297383847172 0.542563620209202 GO:0070577 lysine-acetylated histone binding 1/234 23/18639 0.0434782608695652 3.46321070234114 0.252297383847172 0.542563620209202 GO:0140103 catalytic activity, acting on a glycoprotein 1/234 23/18639 0.0434782608695652 3.46321070234114 0.252297383847172 0.542563620209202 GO:0070851 growth factor receptor binding 3/234 139/18639 0.0215827338129496 1.7191477587161 0.254010664788591 0.542563620209202 GO:0033293 monocarboxylic acid binding 2/234 79/18639 0.0253164556962025 2.01655306718598 0.261180422457447 0.542563620209202 GO:0019957 C-C chemokine binding 1/234 24/18639 0.0416666666666667 3.31891025641026 0.261695880418926 0.542563620209202 GO:0035035 histone acetyltransferase binding 1/234 24/18639 0.0416666666666667 3.31891025641026 0.261695880418926 0.542563620209202 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/234 24/18639 0.0416666666666667 3.31891025641026 0.261695880418926 0.542563620209202 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/234 24/18639 0.0416666666666667 3.31891025641026 0.261695880418926 0.542563620209202 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/234 24/18639 0.0416666666666667 3.31891025641026 0.261695880418926 0.542563620209202 GO:0050699 WW domain binding 1/234 24/18639 0.0416666666666667 3.31891025641026 0.261695880418926 0.542563620209202 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/234 24/18639 0.0416666666666667 3.31891025641026 0.261695880418926 0.542563620209202 GO:0140033 acetylation-dependent protein binding 1/234 24/18639 0.0416666666666667 3.31891025641026 0.261695880418926 0.542563620209202 GO:0016887 ATP hydrolysis activity 7/234 417/18639 0.0167865707434053 1.33711492344586 0.270845489544228 0.547760120397688 GO:0008094 ATP-dependent activity, acting on DNA 4/234 210/18639 0.019047619047619 1.51721611721612 0.27096137496301 0.547760120397688 GO:0008483 transaminase activity 1/234 25/18639 0.04 3.18615384615385 0.270976738005923 0.547760120397688 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/234 25/18639 0.04 3.18615384615385 0.270976738005923 0.547760120397688 GO:0019211 phosphatase activator activity 1/234 25/18639 0.04 3.18615384615385 0.270976738005923 0.547760120397688 GO:0042974 nuclear retinoic acid receptor binding 1/234 25/18639 0.04 3.18615384615385 0.270976738005923 0.547760120397688 GO:0120020 cholesterol transfer activity 1/234 25/18639 0.04 3.18615384615385 0.270976738005923 0.547760120397688 GO:0005254 chloride channel activity 2/234 83/18639 0.0240963855421687 1.91936978683967 0.279807721779548 0.556351036215839 GO:0008135 translation factor activity, RNA binding 2/234 83/18639 0.0240963855421687 1.91936978683967 0.279807721779548 0.556351036215839 GO:0005160 transforming growth factor beta receptor binding 1/234 26/18639 0.0384615384615385 3.06360946745562 0.28014142282953 0.556351036215839 GO:0008198 ferrous iron binding 1/234 26/18639 0.0384615384615385 3.06360946745562 0.28014142282953 0.556351036215839 GO:0120014 phospholipid transfer activity 1/234 26/18639 0.0384615384615385 3.06360946745562 0.28014142282953 0.556351036215839 GO:0180051 translation factor activity 2/234 84/18639 0.0238095238095238 1.89652014652015 0.284460951977779 0.557090896097198 GO:0008509 monoatomic anion transmembrane transporter activity 3/234 149/18639 0.0201342281879195 1.60376871450697 0.287966541612547 0.557090896097198 GO:0004364 glutathione transferase activity 1/234 27/18639 0.037037037037037 2.95014245014245 0.289191382914304 0.557090896097198 GO:0005385 zinc ion transmembrane transporter activity 1/234 27/18639 0.037037037037037 2.95014245014245 0.289191382914304 0.557090896097198 GO:0015252 proton channel activity 1/234 27/18639 0.037037037037037 2.95014245014245 0.289191382914304 0.557090896097198 GO:0019842 vitamin binding 3/234 150/18639 0.02 1.59307692307692 0.291385101037682 0.557090896097198 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/234 86/18639 0.0232558139534884 1.85241502683363 0.293758295198259 0.557090896097198 GO:0050660 flavin adenine dinucleotide binding 2/234 86/18639 0.0232558139534884 1.85241502683363 0.293758295198259 0.557090896097198 GO:0000510 H3-H4 histone complex chaperone activity 3/234 151/18639 0.0198675496688742 1.5825267447784 0.294806568841627 0.557090896097198 GO:0140584 chromatin extrusion motor activity 3/234 151/18639 0.0198675496688742 1.5825267447784 0.294806568841627 0.557090896097198 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/234 151/18639 0.0198675496688742 1.5825267447784 0.294806568841627 0.557090896097198 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/234 151/18639 0.0198675496688742 1.5825267447784 0.294806568841627 0.557090896097198 GO:0019789 SUMO transferase activity 1/234 28/18639 0.0357142857142857 2.84478021978022 0.298128048312867 0.557090896097198 GO:0046875 ephrin receptor binding 1/234 28/18639 0.0357142857142857 2.84478021978022 0.298128048312867 0.557090896097198 GO:0051019 mitogen-activated protein kinase binding 1/234 28/18639 0.0357142857142857 2.84478021978022 0.298128048312867 0.557090896097198 GO:0141052 histone H3 demethylase activity 1/234 28/18639 0.0357142857142857 2.84478021978022 0.298128048312867 0.557090896097198 GO:0015616 DNA translocase activity 3/234 152/18639 0.0197368421052632 1.57211538461538 0.298230638723412 0.557090896097198 GO:0140674 ATP-dependent histone chaperone activity 3/234 152/18639 0.0197368421052632 1.57211538461538 0.298230638723412 0.557090896097198 GO:0061775 cohesin loader activity 3/234 153/18639 0.0196078431372549 1.56184012066365 0.301657007740848 0.561637718359606 GO:0003785 actin monomer binding 1/234 29/18639 0.0344827586206897 2.74668435013263 0.306952831328008 0.565397001086138 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/234 29/18639 0.0344827586206897 2.74668435013263 0.306952831328008 0.565397001086138 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/234 89/18639 0.0224719101123595 1.78997407087295 0.307671866315425 0.565397001086138 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/234 89/18639 0.0224719101123595 1.78997407087295 0.307671866315425 0.565397001086138 GO:0140793 histone H2AXY142 phosphatase activity 2/234 90/18639 0.0222222222222222 1.77008547008547 0.312298613223624 0.569005075574334 GO:0001968 fibronectin binding 1/234 30/18639 0.0333333333333333 2.65512820512821 0.315667126732051 0.569005075574334 GO:0016769 transferase activity, transferring nitrogenous groups 1/234 30/18639 0.0333333333333333 2.65512820512821 0.315667126732051 0.569005075574334 GO:0032452 histone demethylase activity 1/234 30/18639 0.0333333333333333 2.65512820512821 0.315667126732051 0.569005075574334 GO:0048019 receptor antagonist activity 1/234 30/18639 0.0333333333333333 2.65512820512821 0.315667126732051 0.569005075574334 GO:0051721 protein phosphatase 2A binding 1/234 30/18639 0.0333333333333333 2.65512820512821 0.315667126732051 0.569005075574334 GO:0140658 ATP-dependent chromatin remodeler activity 3/234 158/18639 0.0189873417721519 1.51241480038948 0.318812973373326 0.572485340582683 GO:0043178 alcohol binding 2/234 92/18639 0.0217391304347826 1.73160535117057 0.321531944755272 0.572485340582683 GO:0070273 phosphatidylinositol-4-phosphate binding 1/234 31/18639 0.032258064516129 2.56947890818859 0.324272311983526 0.572485340582683 GO:0140457 protein demethylase activity 1/234 31/18639 0.032258064516129 2.56947890818859 0.324272311983526 0.572485340582683 GO:0003689 DNA clamp loader activity 3/234 160/18639 0.01875 1.49350961538462 0.325681229685338 0.572485340582683 GO:0051213 dioxygenase activity 2/234 93/18639 0.021505376344086 1.71298593879239 0.326137417399256 0.572485340582683 GO:0051219 phosphoprotein binding 2/234 93/18639 0.021505376344086 1.71298593879239 0.326137417399256 0.572485340582683 GO:0004866 endopeptidase inhibitor activity 3/234 161/18639 0.0186335403726708 1.4842331581462 0.329115492192333 0.572485340582683 GO:0015106 bicarbonate transmembrane transporter activity 1/234 32/18639 0.03125 2.48918269230769 0.332769747441171 0.572485340582683 GO:0030515 snoRNA binding 1/234 32/18639 0.03125 2.48918269230769 0.332769747441171 0.572485340582683 GO:0051059 NF-kappaB binding 1/234 32/18639 0.03125 2.48918269230769 0.332769747441171 0.572485340582683 GO:0070717 poly-purine tract binding 1/234 32/18639 0.03125 2.48918269230769 0.332769747441171 0.572485340582683 GO:0071813 lipoprotein particle binding 1/234 32/18639 0.03125 2.48918269230769 0.332769747441171 0.572485340582683 GO:0071814 protein-lipid complex binding 1/234 32/18639 0.03125 2.48918269230769 0.332769747441171 0.572485340582683 GO:0120015 sterol transfer activity 1/234 32/18639 0.03125 2.48918269230769 0.332769747441171 0.572485340582683 GO:0005525 GTP binding 6/234 378/18639 0.0158730158730159 1.26434676434676 0.338715641921237 0.579870869494356 GO:0140713 histone chaperone activity 3/234 164/18639 0.0182926829268293 1.45708255159475 0.339415559274499 0.579870869494356 GO:0019239 deaminase activity 1/234 33/18639 0.0303030303030303 2.41375291375291 0.341160776575301 0.579870869494356 GO:0019956 chemokine binding 1/234 33/18639 0.0303030303030303 2.41375291375291 0.341160776575301 0.579870869494356 GO:0004725 protein tyrosine phosphatase activity 2/234 98/18639 0.0204081632653061 1.62558869701727 0.349031929057012 0.580450438010625 GO:0008175 tRNA methyltransferase activity 1/234 34/18639 0.0294117647058824 2.34276018099548 0.34944672617658 0.580450438010625 GO:0015035 protein-disulfide reductase activity 1/234 34/18639 0.0294117647058824 2.34276018099548 0.34944672617658 0.580450438010625 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/234 34/18639 0.0294117647058824 2.34276018099548 0.34944672617658 0.580450438010625 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/234 34/18639 0.0294117647058824 2.34276018099548 0.34944672617658 0.580450438010625 GO:0016831 carboxy-lyase activity 1/234 34/18639 0.0294117647058824 2.34276018099548 0.34944672617658 0.580450438010625 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/234 34/18639 0.0294117647058824 2.34276018099548 0.34944672617658 0.580450438010625 GO:0016874 ligase activity 3/234 167/18639 0.0179640718562874 1.43090741593736 0.349706005939263 0.580450438010625 GO:0030414 peptidase inhibitor activity 3/234 169/18639 0.0177514792899408 1.41397360036413 0.356557544105416 0.588606158266959 GO:0005154 epidermal growth factor receptor binding 1/234 35/18639 0.0285714285714286 2.27582417582418 0.357628906562212 0.588606158266959 GO:0043130 ubiquitin binding 2/234 100/18639 0.02 1.59307692307692 0.358118629194104 0.588606158266959 GO:0140098 catalytic activity, acting on RNA 6/234 387/18639 0.0155038759689922 1.23494335122242 0.358779372088517 0.588606158266959 GO:0051020 GTPase binding 5/234 315/18639 0.0158730158730159 1.26434676434676 0.362135420540226 0.592394936490659 GO:0005484 SNAP receptor activity 1/234 36/18639 0.0277777777777778 2.21260683760684 0.365708611779608 0.596516064170772 GO:0140030 modification-dependent protein binding 3/234 173/18639 0.0173410404624277 1.38128056914184 0.370230744307918 0.602156900224947 GO:0005253 monoatomic anion channel activity 2/234 103/18639 0.0194174757281553 1.54667662434653 0.371661217438467 0.602751430000493 GO:0030280 structural constituent of skin epidermis 1/234 37/18639 0.027027027027027 2.15280665280665 0.373687119807537 0.604305456603046 GO:0004721 phosphoprotein phosphatase activity 3/234 175/18639 0.0171428571428571 1.36549450549451 0.37704862043441 0.608004328107909 GO:0042162 telomeric DNA binding 1/234 38/18639 0.0263157894736842 2.09615384615385 0.381565692754803 0.610743230949342 GO:0043531 ADP binding 1/234 38/18639 0.0263157894736842 2.09615384615385 0.381565692754803 0.610743230949342 GO:0000149 SNARE binding 2/234 106/18639 0.0188679245283019 1.50290275761974 0.385089010568953 0.610743230949342 GO:0004497 monooxygenase activity 2/234 106/18639 0.0188679245283019 1.50290275761974 0.385089010568953 0.610743230949342 GO:0008013 beta-catenin binding 2/234 106/18639 0.0188679245283019 1.50290275761974 0.385089010568953 0.610743230949342 GO:0019001 guanyl nucleotide binding 6/234 400/18639 0.015 1.19480769230769 0.387884732282945 0.610743230949342 GO:0032561 guanyl ribonucleotide binding 6/234 400/18639 0.015 1.19480769230769 0.387884732282945 0.610743230949342 GO:0000217 DNA secondary structure binding 1/234 39/18639 0.0256410256410256 2.04240631163708 0.389345577056474 0.610743230949342 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/234 39/18639 0.0256410256410256 2.04240631163708 0.389345577056474 0.610743230949342 GO:0019888 protein phosphatase regulator activity 2/234 107/18639 0.0186915887850467 1.48885693745507 0.389537643768043 0.610743230949342 GO:0015036 disulfide oxidoreductase activity 1/234 40/18639 0.025 1.99134615384615 0.397028003667699 0.617356730977795 GO:0032451 demethylase activity 1/234 40/18639 0.025 1.99134615384615 0.397028003667699 0.617356730977795 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/234 40/18639 0.025 1.99134615384615 0.397028003667699 0.617356730977795 GO:0001530 lipopolysaccharide binding 1/234 41/18639 0.024390243902439 1.94277673545966 0.404614188255137 0.624009892513371 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/234 41/18639 0.024390243902439 1.94277673545966 0.404614188255137 0.624009892513371 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/234 41/18639 0.024390243902439 1.94277673545966 0.404614188255137 0.624009892513371 GO:1902936 phosphatidylinositol bisphosphate binding 2/234 111/18639 0.018018018018018 1.43520443520444 0.407186304785276 0.625339457277456 GO:0005200 structural constituent of cytoskeleton 2/234 112/18639 0.0178571428571429 1.42239010989011 0.41156036474055 0.625339457277456 GO:0043022 ribosome binding 2/234 112/18639 0.0178571428571429 1.42239010989011 0.41156036474055 0.625339457277456 GO:0019894 kinesin binding 1/234 42/18639 0.0238095238095238 1.89652014652015 0.412105331386027 0.625339457277456 GO:0035198 miRNA binding 1/234 42/18639 0.0238095238095238 1.89652014652015 0.412105331386027 0.625339457277456 GO:0051879 Hsp90 protein binding 1/234 42/18639 0.0238095238095238 1.89652014652015 0.412105331386027 0.625339457277456 GO:0140097 catalytic activity, acting on DNA 5/234 336/18639 0.0148809523809524 1.18532509157509 0.414348657547605 0.627062406876857 GO:0008200 ion channel inhibitor activity 1/234 43/18639 0.0232558139534884 1.85241502683363 0.419502618714933 0.629810297593242 GO:0008375 acetylglucosaminyltransferase activity 1/234 43/18639 0.0232558139534884 1.85241502683363 0.419502618714933 0.629810297593242 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/234 43/18639 0.0232558139534884 1.85241502683363 0.419502618714933 0.629810297593242 GO:0140597 protein carrier chaperone 3/234 188/18639 0.0159574468085106 1.27107201309329 0.420925240478515 0.630274301880528 GO:0035401 histone H3Y41 kinase activity 2/234 115/18639 0.0173913043478261 1.38528428093645 0.424586223963194 0.632389757018832 GO:0140801 histone H2AXY142 kinase activity 2/234 115/18639 0.0173913043478261 1.38528428093645 0.424586223963194 0.632389757018832 GO:0016248 channel inhibitor activity 1/234 44/18639 0.0227272727272727 1.81031468531469 0.426807221168187 0.632389757018832 GO:0030547 signaling receptor inhibitor activity 1/234 44/18639 0.0227272727272727 1.81031468531469 0.426807221168187 0.632389757018832 GO:0019208 phosphatase regulator activity 2/234 117/18639 0.0170940170940171 1.36160420775805 0.4331870672688 0.634768700365245 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/234 45/18639 0.0222222222222222 1.77008547008547 0.43402029512606 0.634768700365245 GO:0042605 peptide antigen binding 1/234 45/18639 0.0222222222222222 1.77008547008547 0.43402029512606 0.634768700365245 GO:0046915 transition metal ion transmembrane transporter activity 1/234 45/18639 0.0222222222222222 1.77008547008547 0.43402029512606 0.634768700365245 GO:0141110 transporter inhibitor activity 1/234 45/18639 0.0222222222222222 1.77008547008547 0.43402029512606 0.634768700365245 GO:0032182 ubiquitin-like protein binding 2/234 120/18639 0.0166666666666667 1.3275641025641 0.445958567961386 0.636205943876811 GO:0001784 phosphotyrosine residue binding 1/234 47/18639 0.0212765957446809 1.69476268412439 0.448176411423806 0.636205943876811 GO:0005504 fatty acid binding 1/234 47/18639 0.0212765957446809 1.69476268412439 0.448176411423806 0.636205943876811 GO:0016791 phosphatase activity 4/234 273/18639 0.0146520146520147 1.16708932093547 0.448865388290606 0.636205943876811 GO:0015108 chloride transmembrane transporter activity 2/234 121/18639 0.0165289256198347 1.31659249841068 0.450180177914087 0.636205943876811 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/234 122/18639 0.0163934426229508 1.30580075662043 0.454383637390906 0.636205943876811 GO:0005126 cytokine receptor binding 4/234 275/18639 0.0145454545454545 1.1586013986014 0.454404108682248 0.636205943876811 GO:1901681 sulfur compound binding 4/234 275/18639 0.0145454545454545 1.1586013986014 0.454404108682248 0.636205943876811 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/234 48/18639 0.0208333333333333 1.65945512820513 0.455121695402228 0.636205943876811 GO:0032266 phosphatidylinositol-3-phosphate binding 1/234 48/18639 0.0208333333333333 1.65945512820513 0.455121695402228 0.636205943876811 GO:0140693 molecular condensate scaffold activity 1/234 48/18639 0.0208333333333333 1.65945512820513 0.455121695402228 0.636205943876811 GO:0008017 microtubule binding 4/234 276/18639 0.0144927536231884 1.15440356744705 0.457166742823329 0.636205943876811 GO:0016829 lyase activity 3/234 200/18639 0.015 1.19480769230769 0.460488533941793 0.636205943876811 GO:0004674 protein serine/threonine kinase activity 6/234 433/18639 0.0138568129330254 1.10374844554983 0.461419596365192 0.636205943876811 GO:0005004 GPI-linked ephrin receptor activity 1/234 49/18639 0.0204081632653061 1.62558869701727 0.461979934511253 0.636205943876811 GO:0005008 hepatocyte growth factor receptor activity 1/234 49/18639 0.0204081632653061 1.62558869701727 0.461979934511253 0.636205943876811 GO:0005009 insulin receptor activity 1/234 49/18639 0.0204081632653061 1.62558869701727 0.461979934511253 0.636205943876811 GO:0005011 macrophage colony-stimulating factor receptor activity 1/234 49/18639 0.0204081632653061 1.62558869701727 0.461979934511253 0.636205943876811 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/234 49/18639 0.0204081632653061 1.62558869701727 0.461979934511253 0.636205943876811 GO:0005020 stem cell factor receptor activity 1/234 49/18639 0.0204081632653061 1.62558869701727 0.461979934511253 0.636205943876811 GO:0008288 boss receptor activity 1/234 49/18639 0.0204081632653061 1.62558869701727 0.461979934511253 0.636205943876811 GO:0036332 placental growth factor receptor activity 1/234 49/18639 0.0204081632653061 1.62558869701727 0.461979934511253 0.636205943876811 GO:0038062 protein tyrosine kinase collagen receptor activity 1/234 49/18639 0.0204081632653061 1.62558869701727 0.461979934511253 0.636205943876811 GO:0060175 brain-derived neurotrophic factor receptor activity 1/234 49/18639 0.0204081632653061 1.62558869701727 0.461979934511253 0.636205943876811 GO:0030246 carbohydrate binding 4/234 280/18639 0.0142857142857143 1.13791208791209 0.468170010847596 0.636244013720913 GO:0005006 epidermal growth factor receptor activity 1/234 50/18639 0.02 1.59307692307692 0.468752215055867 0.636244013720913 GO:0005007 fibroblast growth factor receptor activity 1/234 50/18639 0.02 1.59307692307692 0.468752215055867 0.636244013720913 GO:0005017 platelet-derived growth factor receptor activity 1/234 50/18639 0.02 1.59307692307692 0.468752215055867 0.636244013720913 GO:0005019 platelet-derived growth factor beta-receptor activity 1/234 50/18639 0.02 1.59307692307692 0.468752215055867 0.636244013720913 GO:0032813 tumor necrosis factor receptor superfamily binding 1/234 50/18639 0.02 1.59307692307692 0.468752215055867 0.636244013720913 GO:0005010 insulin-like growth factor receptor activity 1/234 51/18639 0.0196078431372549 1.56184012066365 0.475439609841865 0.63892281001086 GO:0005021 vascular endothelial growth factor receptor activity 1/234 51/18639 0.0196078431372549 1.56184012066365 0.475439609841865 0.63892281001086 GO:0005030 neurotrophin receptor activity 1/234 51/18639 0.0196078431372549 1.56184012066365 0.475439609841865 0.63892281001086 GO:0106310 protein serine kinase activity 5/234 361/18639 0.0138504155124654 1.10323886639676 0.475581642610408 0.63892281001086 GO:0031267 small GTPase binding 4/234 283/18639 0.0141342756183746 1.12584941560207 0.476370010290783 0.63892281001086 GO:0030159 signaling receptor complex adaptor activity 1/234 52/18639 0.0192307692307692 1.53180473372781 0.482043178342888 0.64010927140234 GO:0035591 signaling adaptor activity 2/234 129/18639 0.0155038759689922 1.23494335122242 0.483282940626412 0.64010927140234 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/234 130/18639 0.0153846153846154 1.22544378698225 0.487334270209231 0.64010927140234 GO:0005003 ephrin receptor activity 1/234 53/18639 0.0188679245283019 1.50290275761974 0.488563966865391 0.64010927140234 GO:0005005 transmembrane-ephrin receptor activity 1/234 53/18639 0.0188679245283019 1.50290275761974 0.488563966865391 0.64010927140234 GO:0005544 calcium-dependent phospholipid binding 1/234 53/18639 0.0188679245283019 1.50290275761974 0.488563966865391 0.64010927140234 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/234 53/18639 0.0188679245283019 1.50290275761974 0.488563966865391 0.64010927140234 GO:0017046 peptide hormone binding 1/234 53/18639 0.0188679245283019 1.50290275761974 0.488563966865391 0.64010927140234 GO:0038064 collagen receptor activity 1/234 53/18639 0.0188679245283019 1.50290275761974 0.488563966865391 0.64010927140234 GO:0140296 general transcription initiation factor binding 1/234 53/18639 0.0188679245283019 1.50290275761974 0.488563966865391 0.64010927140234 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/234 54/18639 0.0185185185185185 1.47507122507123 0.495003008711592 0.644560121105717 GO:0051287 NAD binding 1/234 54/18639 0.0185185185185185 1.47507122507123 0.495003008711592 0.644560121105717 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/234 132/18639 0.0151515151515152 1.20687645687646 0.495377478234959 0.644560121105717 GO:0030170 pyridoxal phosphate binding 1/234 56/18639 0.0178571428571429 1.42239010989011 0.50763992152639 0.659000448587011 GO:0016779 nucleotidyltransferase activity 2/234 136/18639 0.0147058823529412 1.17138009049774 0.511222297638082 0.662132312272664 GO:0070279 vitamin B6 binding 1/234 57/18639 0.0175438596491228 1.3974358974359 0.513839795516748 0.662651182189709 GO:0001664 G protein-coupled receptor binding 4/234 297/18639 0.0134680134680135 1.07277907277907 0.513964432829121 0.662651182189709 GO:0061980 regulatory RNA binding 1/234 58/18639 0.0172413793103448 1.37334217506631 0.519961929186379 0.668462111081586 GO:0001786 phosphatidylserine binding 1/234 59/18639 0.0169491525423729 1.35006518904824 0.526007293191028 0.668462111081586 GO:0004879 nuclear receptor activity 1/234 59/18639 0.0169491525423729 1.35006518904824 0.526007293191028 0.668462111081586 GO:0015459 potassium channel regulator activity 1/234 59/18639 0.0169491525423729 1.35006518904824 0.526007293191028 0.668462111081586 GO:0031593 polyubiquitin modification-dependent protein binding 1/234 59/18639 0.0169491525423729 1.35006518904824 0.526007293191028 0.668462111081586 GO:0036002 pre-mRNA binding 1/234 59/18639 0.0169491525423729 1.35006518904824 0.526007293191028 0.668462111081586 GO:0004713 protein tyrosine kinase activity 2/234 140/18639 0.0142857142857143 1.13791208791209 0.526738695304571 0.668462111081586 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/234 60/18639 0.0166666666666667 1.3275641025641 0.531976846118547 0.672095747551557 GO:0098531 ligand-modulated transcription factor activity 1/234 60/18639 0.0166666666666667 1.3275641025641 0.531976846118547 0.672095747551557 GO:0015026 coreceptor activity 1/234 61/18639 0.0163934426229508 1.30580075662043 0.537871534638287 0.675022812871997 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/234 61/18639 0.0163934426229508 1.30580075662043 0.537871534638287 0.675022812871997 GO:0019905 syntaxin binding 1/234 61/18639 0.0163934426229508 1.30580075662043 0.537871534638287 0.675022812871997 GO:0015179 L-amino acid transmembrane transporter activity 1/234 62/18639 0.0161290322580645 1.28473945409429 0.543692293648657 0.680818226117566 GO:0038024 cargo receptor activity 1/234 65/18639 0.0153846153846154 1.22544378698225 0.560720169091307 0.700590763147196 GO:0008173 RNA methyltransferase activity 1/234 67/18639 0.0149253731343284 1.18886337543054 0.571719061750489 0.709633747699072 GO:0016500 protein-hormone receptor activity 1/234 67/18639 0.0149253731343284 1.18886337543054 0.571719061750489 0.709633747699072 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/234 67/18639 0.0149253731343284 1.18886337543054 0.571719061750489 0.709633747699072 GO:0003777 microtubule motor activity 1/234 68/18639 0.0147058823529412 1.17138009049774 0.577115235536316 0.710102659377294 GO:0005548 phospholipid transporter activity 1/234 68/18639 0.0147058823529412 1.17138009049774 0.577115235536316 0.710102659377294 GO:0030145 manganese ion binding 1/234 68/18639 0.0147058823529412 1.17138009049774 0.577115235536316 0.710102659377294 GO:0140223 general transcription initiation factor activity 1/234 68/18639 0.0147058823529412 1.17138009049774 0.577115235536316 0.710102659377294 GO:0004386 helicase activity 2/234 155/18639 0.0129032258064516 1.02779156327543 0.581909944167315 0.714449085463558 GO:0003924 GTPase activity 4/234 331/18639 0.0120845921450151 0.962584243551011 0.599603405189911 0.734092654503376 GO:0042393 histone binding 3/234 247/18639 0.0121457489878543 0.967455621301775 0.60212180780017 0.734092654503376 GO:0005178 integrin binding 2/234 161/18639 0.0124223602484472 0.989488772097468 0.602620780155585 0.734092654503376 GO:0004521 RNA endonuclease activity 1/234 73/18639 0.0136986301369863 1.09114857744995 0.603097322162668 0.734092654503376 GO:0003678 DNA helicase activity 1/234 74/18639 0.0135135135135135 1.07640332640333 0.608099758153939 0.738593268487402 GO:0015103 inorganic anion transmembrane transporter activity 2/234 165/18639 0.0121212121212121 0.965501165501165 0.615994289002002 0.74657980208808 GO:0017022 myosin binding 1/234 76/18639 0.0131578947368421 1.04807692307692 0.61791706556323 0.747309955360658 GO:0003724 RNA helicase activity 1/234 77/18639 0.012987012987013 1.03446553446553 0.622733496455769 0.75152912365451 GO:0003713 transcription coactivator activity 3/234 256/18639 0.01171875 0.933443509615385 0.626318542823326 0.754053162287974 GO:0019199 transmembrane receptor protein kinase activity 1/234 78/18639 0.0128205128205128 1.02120315581854 0.627489468971088 0.754053162287974 GO:0008186 ATP-dependent activity, acting on RNA 1/234 79/18639 0.0126582278481013 1.00827653359299 0.632185738798186 0.758087135931723 GO:0000049 tRNA binding 1/234 80/18639 0.0125 0.995673076923077 0.636823052220666 0.760425838727631 GO:0048306 calcium-dependent protein binding 1/234 80/18639 0.0125 0.995673076923077 0.636823052220666 0.760425838727631 GO:0015101 organic cation transmembrane transporter activity 1/234 81/18639 0.0123456790123457 0.98338081671415 0.641402146233294 0.764281294248514 GO:0061630 ubiquitin protein ligase activity 4/234 353/18639 0.0113314447592068 0.902593157550665 0.649961588808123 0.771739906271081 GO:0001540 amyloid-beta binding 1/234 83/18639 0.0120481927710843 0.959684893419833 0.65038857825319 0.771739906271081 GO:0141003 histone H2AX kinase activity 4/234 354/18639 0.0112994350282486 0.900043459365493 0.652148487554827 0.772209296979147 GO:0005319 lipid transporter activity 2/234 178/18639 0.0112359550561798 0.894987035436474 0.657075837419044 0.776419465509768 GO:0140996 histone H3 kinase activity 4/234 357/18639 0.0112044817927171 0.892480068950657 0.658654808580237 0.77666379511753 GO:0016853 isomerase activity 2/234 180/18639 0.0111111111111111 0.885042735042735 0.663075899163684 0.779071385932817 GO:0016209 antioxidant activity 1/234 86/18639 0.0116279069767442 0.926207513416816 0.6634494841336 0.779071385932817 GO:0035173 histone kinase activity 4/234 360/18639 0.0111111111111111 0.885042735042735 0.665079250634524 0.779368231592424 GO:0042578 phosphoric ester hydrolase activity 4/234 363/18639 0.0110192837465565 0.877728332273787 0.671421460506315 0.785174683154079 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/234 91/18639 0.010989010989011 0.875316990701606 0.684146742415561 0.796763490138287 GO:0072341 modified amino acid binding 1/234 91/18639 0.010989010989011 0.875316990701606 0.684146742415561 0.796763490138287 GO:0052689 carboxylic ester hydrolase activity 1/234 92/18639 0.0108695652173913 0.865802675585284 0.688131520411828 0.799758604831817 GO:0061659 ubiquitin-like protein ligase activity 4/234 372/18639 0.010752688172043 0.856492969396195 0.689952085275017 0.800231312019794 GO:0016410 N-acyltransferase activity 1/234 94/18639 0.0106382978723404 0.847381342062193 0.695951524164507 0.803895025871655 GO:0042562 hormone binding 1/234 94/18639 0.0106382978723404 0.847381342062193 0.695951524164507 0.803895025871655 GO:0004896 cytokine receptor activity 1/234 96/18639 0.0104166666666667 0.829727564102564 0.703576260798989 0.809398706528918 GO:0016407 acetyltransferase activity 1/234 96/18639 0.0104166666666667 0.829727564102564 0.703576260798989 0.809398706528918 GO:0016758 hexosyltransferase activity 2/234 197/18639 0.0101522842639594 0.808668488871535 0.710722108277458 0.814639659000219 GO:0042626 ATPase-coupled transmembrane transporter activity 1/234 98/18639 0.0102040816326531 0.812794348508634 0.711010585770509 0.814639659000219 GO:0015171 amino acid transmembrane transporter activity 1/234 102/18639 0.00980392156862745 0.780920060331825 0.725326824375825 0.829363601205489 GO:0004843 cysteine-type deubiquitinase activity 1/234 108/18639 0.00925925925925926 0.737535612535613 0.745487724720682 0.850697685870778 GO:0016755 aminoacyltransferase activity 5/234 496/18639 0.0100806451612903 0.802962158808933 0.74961930953789 0.853691205630675 GO:0004222 metalloendopeptidase activity 1/234 110/18639 0.00909090909090909 0.724125874125874 0.751875015052664 0.85454067975865 GO:0101005 deubiquitinase activity 1/234 115/18639 0.00869565217391304 0.692642140468227 0.767153528074839 0.870007418129048 GO:0009055 electron transfer activity 1/234 116/18639 0.00862068965517241 0.686671087533156 0.770094905446383 0.870007418129048 GO:0015294 solute:monoatomic cation symporter activity 1/234 116/18639 0.00862068965517241 0.686671087533156 0.770094905446383 0.870007418129048 GO:0022853 active monoatomic ion transmembrane transporter activity 1/234 118/18639 0.00847457627118644 0.67503259452412 0.775867125262871 0.870978356938462 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/234 229/18639 0.00873362445414847 0.695666778636211 0.785164300418891 0.870978356938462 GO:0005085 guanyl-nucleotide exchange factor activity 2/234 230/18639 0.00869565217391304 0.692642140468227 0.787194596315614 0.870978356938462 GO:0019783 ubiquitin-like protein peptidase activity 1/234 127/18639 0.0078740157480315 0.627195639006663 0.800107244517876 0.870978356938462 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/234 130/18639 0.00769230769230769 0.612721893491124 0.807592433102183 0.870978356938462 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 2/234 243/18639 0.00823045267489712 0.655587211142767 0.812093328432224 0.870978356938462 GO:0005179 hormone activity 1/234 132/18639 0.00757575757575758 0.603438228438228 0.812426834491389 0.870978356938462 GO:0004676 3-phosphoinositide-dependent protein kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:0004711 ribosomal protein S6 kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:0035175 histone H3S10 kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:0035979 histone H2AXS139 kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:0044022 histone H3S28 kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:0044023 histone H4S1 kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:0044024 histone H2AS1 kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:0044025 histone H2BS14 kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:0072354 histone H3T3 kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:0072371 histone H2AS121 kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:0072518 Rho-dependent protein serine/threonine kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:0140823 histone H2BS36 kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:0140855 histone H3S57 kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:0140995 histone H2A kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:0140997 histone H4 kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:0140998 histone H2B kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:1990244 histone H2AT120 kinase activity 2/234 245/18639 0.00816326530612245 0.650235478806907 0.815685528493024 0.870978356938462 GO:0004677 DNA-dependent protein kinase activity 2/234 246/18639 0.00813008130081301 0.647592245153221 0.817458598721426 0.870978356938462 GO:0140857 histone H3T45 kinase activity 2/234 246/18639 0.00813008130081301 0.647592245153221 0.817458598721426 0.870978356938462 GO:0004842 ubiquitin-protein transferase activity 4/234 449/18639 0.0089086859688196 0.709611101593284 0.818503424593204 0.870978356938462 GO:0033218 amide binding 2/234 247/18639 0.00809716599190283 0.644970414201184 0.819216450075886 0.870978356938462 GO:0035402 histone H3T11 kinase activity 2/234 247/18639 0.00809716599190283 0.644970414201184 0.819216450075886 0.870978356938462 GO:0035403 histone H3T6 kinase activity 2/234 247/18639 0.00809716599190283 0.644970414201184 0.819216450075886 0.870978356938462 GO:0015297 antiporter activity 1/234 135/18639 0.00740740740740741 0.59002849002849 0.819452577065019 0.870978356938462 GO:0004679 AMP-activated protein kinase activity 2/234 248/18639 0.00806451612903226 0.642369727047146 0.820959183176406 0.870978356938462 GO:0019838 growth factor binding 1/234 136/18639 0.00735294117647059 0.585690045248869 0.821735764320034 0.870978356938462 GO:0140101 catalytic activity, acting on a tRNA 1/234 139/18639 0.00719424460431655 0.573049252905368 0.828414256714902 0.876415830468475 GO:0020037 heme binding 1/234 142/18639 0.00704225352112676 0.560942578548212 0.834843575269999 0.881569894781379 GO:0019955 cytokine binding 1/234 144/18639 0.00694444444444444 0.553151709401709 0.838995943935623 0.884304849660265 GO:0008194 UDP-glycosyltransferase activity 1/234 145/18639 0.00689655172413793 0.549336870026525 0.841032978221596 0.88480421128889 GO:0015293 symporter activity 1/234 146/18639 0.00684931506849315 0.545574288724974 0.84304434856312 0.8852747704763 GO:0016757 glycosyltransferase activity 2/234 267/18639 0.00749063670411985 0.596658023624316 0.851331301718596 0.89106700816285 GO:0008514 organic anion transmembrane transporter activity 2/234 269/18639 0.00743494423791822 0.592221904489562 0.854240718313162 0.89106700816285 GO:0046906 tetrapyrrole binding 1/234 152/18639 0.00657894736842105 0.524038461538462 0.854591378876796 0.89106700816285 GO:0019787 ubiquitin-like protein transferase activity 4/234 479/18639 0.00835073068893528 0.665167817568653 0.855125668007337 0.89106700816285 GO:0003774 cytoskeletal motor activity 1/234 153/18639 0.0065359477124183 0.52061337355455 0.856431894771361 0.89106700816285 GO:0005506 iron ion binding 1/234 154/18639 0.00649350649350649 0.517232767232767 0.858249212559065 0.891319365703543 GO:0140375 immune receptor activity 1/234 156/18639 0.00641025641025641 0.51060157790927 0.861815414786745 0.893383744998714 GO:0099106 ion channel regulator activity 1/234 160/18639 0.00625 0.497836538461538 0.868682011418213 0.898855609621039 GO:0015291 secondary active transmembrane transporter activity 2/234 287/18639 0.00696864111498258 0.555079067274189 0.878183766636244 0.905548451777148 GO:0015399 primary active transmembrane transporter activity 1/234 166/18639 0.00602409638554217 0.479842446709917 0.878350000045326 0.905548451777148 GO:0016247 channel regulator activity 1/234 168/18639 0.00595238095238095 0.474130036630037 0.881412477041151 0.907053567282348 GO:0141108 transporter regulator activity 1/234 170/18639 0.00588235294117647 0.468552036199095 0.884398178931821 0.908474354401834 GO:0003823 antigen binding 1/234 174/18639 0.00574712643678161 0.457780725022104 0.890146876421412 0.912723065316158 GO:0008237 metallopeptidase activity 1/234 184/18639 0.00543478260869565 0.432901337792642 0.903303531888898 0.92397312553034 GO:0015078 proton transmembrane transporter activity 1/234 185/18639 0.00540540540540541 0.430561330561331 0.904529593852485 0.92397312553034 GO:0008234 cysteine-type peptidase activity 1/234 187/18639 0.0053475935828877 0.425956396544632 0.906935471670353 0.92397312553034 GO:0046943 carboxylic acid transmembrane transporter activity 1/234 188/18639 0.00531914893617021 0.423690671031097 0.90811567433831 0.92397312553034 GO:0005342 organic acid transmembrane transporter activity 1/234 189/18639 0.00529100529100529 0.421448921448921 0.909280973357596 0.92397312553034 GO:0005216 monoatomic ion channel activity 3/234 448/18639 0.00669642857142857 0.533396291208791 0.922784007133434 0.936013885371906 GO:0008168 methyltransferase activity 1/234 204/18639 0.00490196078431373 0.390460030165912 0.925094049015722 0.936678410989085 GO:0005516 calmodulin binding 1/234 207/18639 0.00483091787439614 0.384801189149015 0.927910545949794 0.937170114657616 GO:0022804 active transmembrane transporter activity 3/234 457/18639 0.00656455142231947 0.522891769062447 0.928891226718945 0.937170114657616 GO:0016741 transferase activity, transferring one-carbon groups 1/234 215/18639 0.00465116279069767 0.370483005366726 0.934916208881666 0.941570416774062 GO:0000287 magnesium ion binding 1/234 230/18639 0.00434782608695652 0.346321070234114 0.946275473396197 0.951317793858344 GO:0004175 endopeptidase activity 2/234 405/18639 0.00493827160493827 0.39335232668566 0.964505732568736 0.967925965662951 GO:0005261 monoatomic cation channel activity 1/234 341/18639 0.00293255131964809 0.233588991653508 0.987069378161447 0.988816403609521 GO:0046873 metal ion transmembrane transporter activity 1/234 450/18639 0.00222222222222222 0.177008547008547 0.99683389482367 0.99683389482367