category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Metabolism Lipid metabolism hsa00565 Ether lipid metabolism 2/24 51/9376 15.3202614379085 CHPT1/PLD1 5.1945822181477 Metabolism Carbohydrate metabolism hsa00562 Inositol phosphate metabolism 2/24 78/9376 10.017094017094 PIKFYVE/OCRL 4.05096171065038 Environmental Information Processing Signal transduction hsa04070 Phosphatidylinositol signaling system 2/24 98/9376 7.97278911564626 PIKFYVE/OCRL 3.51504908811887 Human Diseases Cancer: overview hsa05231 Choline metabolism in cancer 2/24 99/9376 7.89225589225589 CHPT1/PLD1 3.49232153769658 Metabolism Lipid metabolism hsa00564 Glycerophospholipid metabolism 2/24 104/9376 7.51282051282051 CHPT1/PLD1 3.38328106173591 Organismal Systems Digestive system hsa04980 Cobalamin transport and metabolism 1/24 18/9376 21.7037037037037 MMAA 4.45381102331864 Cellular Processes Transport and catabolism hsa04145 Phagosome 2/24 155/9376 5.04086021505376 PIKFYVE/ATP6V0C 2.56974290267534 Organismal Systems Excretory system hsa04966 Collecting duct acid secretion 1/24 28/9376 13.952380952381 ATP6V0C 3.47702876124545 Organismal Systems Excretory system hsa04960 Aldosterone-regulated sodium reabsorption 1/24 38/9376 10.280701754386 SCNN1A 2.90392028099813 Genetic Information Processing Replication and repair hsa03440 Homologous recombination 1/24 41/9376 9.52845528455285 RAD52 2.77232508062773 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 3/24 480/9376 2.44166666666667 RAB39B/HAP1/MAP3K10 1.64258214850892 Human Diseases Infectious disease: bacterial hsa05110 Vibrio cholerae infection 1/24 51/9376 7.66013071895425 ATP6V0C 2.41591934289937 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 2/24 238/9376 3.28291316526611 RPL39/OAS2 1.80713794196396 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 2/24 250/9376 3.12533333333333 PIKFYVE/ATP6V0C 1.72542400456024 Metabolism Amino acid metabolism hsa00310 Lysine degradation 1/24 63/9376 6.2010582010582 EZH2 2.09824499999998 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 1/24 70/9376 5.58095238095238 CXADR 1.9487776186565 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 1/24 71/9376 5.50234741784038 ATP6V0C 1.92907449604314 Human Diseases Cancer: specific types hsa05212 Pancreatic cancer 1/24 77/9376 5.07359307359307 PLD1 1.81820937295977 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 1/24 78/9376 5.00854700854701 ARHGEF26 1.80085406852609 Organismal Systems Nervous system hsa04721 Synaptic vesicle cycle 1/24 79/9376 4.94514767932489 ATP6V0C 1.78379279333144 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 2/24 308/9376 2.53679653679654 HAP1/MAP3K10 1.38923266291575 Genetic Information Processing Chromosome hsa03083 Polycomb repressive complex 1/24 83/9376 4.70682730923695 EZH2 1.71831365573582 Organismal Systems Sensory system hsa04742 Taste transduction 1/24 86/9376 4.54263565891473 SCNN1A 1.67188679791251 Organismal Systems Nervous system hsa04727 GABAergic synapse 1/24 89/9376 4.38951310861423 HAP1 1.62754726034769 Organismal Systems Endocrine system hsa04912 GnRH signaling pathway 1/24 93/9376 4.20071684587814 PLD1 1.57138847883527 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 1/24 95/9376 4.11228070175439 ATP6V0C 1.54447963464196 Organismal Systems Immune system hsa04666 Fc gamma R-mediated phagocytosis 1/24 98/9376 3.98639455782313 PLD1 1.50546980456994 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 2/24 368/9376 2.1231884057971 RAB39B/HAP1 1.11352851371371 Human Diseases Endocrine and metabolic disease hsa04931 Insulin resistance 1/24 109/9376 3.58409785932722 PPP1R3D 1.37464840889396 Organismal Systems Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action 1/24 115/9376 3.39710144927536 PLD1 1.31022355405774 Organismal Systems Nervous system hsa04724 Glutamatergic synapse 1/24 116/9376 3.36781609195402 PLD1 1.29990160206737 Environmental Information Processing Signal transduction hsa04071 Sphingolipid signaling pathway 1/24 125/9376 3.12533333333333 PLD1 1.21178822932738 Human Diseases Infectious disease: viral hsa05162 Measles 1/24 136/9376 2.87254901960784 OAS2 1.11430909189937 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 1/24 138/9376 2.83091787439614 ATP6V0C 1.09763624327159 Organismal Systems Endocrine system hsa04910 Insulin signaling pathway 1/24 138/9376 2.83091787439614 PPP1R3D 1.09763624327159 Environmental Information Processing Signal transduction hsa04072 Phospholipase D signaling pathway 1/24 149/9376 2.62192393736018 PLD1 1.01095626347205 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 1/24 154/9376 2.53679653679654 PHOSPHO2 0.974099195393406 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 1/24 156/9376 2.5042735042735 OAS2 0.959760019562438 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 1/24 157/9376 2.48832271762208 ANO7 0.952673400586972 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 1/24 160/9376 2.44166666666667 CXADR 0.931735462488607 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 1/24 169/9376 2.31163708086785 RAB39B 0.87163964807806 Human Diseases Infectious disease: viral hsa05164 Influenza A 1/24 173/9376 2.25818882466281 OAS2 0.84614184661012 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 1/24 178/9376 2.19475655430712 INVS 0.815232960483528 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 1/24 180/9376 2.17037037037037 OAS2 0.803154504951497 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 1/24 181/9376 2.15837937384899 ATP6V0C 0.7971742217917 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 1/24 187/9376 2.08912655971479 OAS2 0.762086093061749 Cellular Processes Cell motility hsa04814 Motor proteins 1/24 194/9376 2.01374570446735 MYO7B 0.722770232511892 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 1/24 205/9376 1.90569105691057 OAS2 0.664182874134183 NA NA hsa04382 Cornified envelope formation 1/24 217/9376 1.80030721966206 S100A5 0.604229023238884 Genetic Information Processing Translation hsa03010 Ribosome 1/24 222/9376 1.75975975975976 RPL39 0.580345111884155 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 1/24 226/9376 1.72861356932153 PLD1 0.561668331241315 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 1/24 227/9376 1.72099853157122 PLD1 0.557056832003947 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 1/24 232/9376 1.68390804597701 PIKFYVE 0.534333750675002 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 1/24 238/9376 1.64145658263305 PLD1 0.507772501484353 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 1/24 248/9376 1.5752688172043 ARHGEF26 0.465101637075652 Cellular Processes Transport and catabolism hsa04144 Endocytosis 1/24 250/9376 1.56266666666667 PLD1 0.456793557041669 NA NA hsa04517 IgSF CAM signaling 1/24 299/9376 1.30657748049052 CXADR 0.272925231405819 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 1/24 300/9376 1.30222222222222 MAP3K10 0.269512422888904 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 1/24 323/9376 1.20949432404541 EZH2 0.194095859861871 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 1/24 333/9376 1.17317317317317 ATP6V0C 0.162999201246848 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 1/24 370/9376 1.05585585585586 HRH4 0.0555319100356782 NA NA hsa04519 Cadherin signaling 1/24 404/9376 0.966996699669967 LHFPL2 -0.0343512410184038