category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Organismal Systems Immune system hsa04612 Antigen processing and presentation 2/4 82/9376 57.1707317073171 HSPA1B/HSP90AA1 10.553953278685 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 2/4 139/9376 33.726618705036 HSPA1B/HSP90AA1 8.03049948888235 Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 2/4 174/9376 26.9425287356322 HSPA1B/HSP90AA1 7.13584339006884 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 2/4 216/9376 21.7037037037037 HSPA1B/HSP90AA1 6.35955424940412 Human Diseases Infectious disease: bacterial hsa05134 Legionellosis 1/4 56/9376 41.8571428571429 HSPA1B 6.33510101671734 Organismal Systems Aging hsa04213 Longevity regulating pathway - multiple species 1/4 62/9376 37.8064516129032 HSPA1B 6.00691065510361 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 1/4 94/9376 24.936170212766 HSP90AA1 4.81833845776901 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 1/4 103/9376 22.7572815533981 SERPINB9 4.58682961829887 Human Diseases Cancer: specific types hsa05215 Prostate cancer 1/4 106/9376 22.1132075471698 HSP90AA1 4.51613355099578 Organismal Systems Immune system hsa04659 Th17 cell differentiation 1/4 109/9376 21.5045871559633 HSP90AA1 4.4483012481402 Organismal Systems Endocrine system hsa04914 Progesterone-mediated oocyte maturation 1/4 110/9376 21.3090909090909 HSP90AA1 4.42629313607939 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 1/4 112/9376 20.9285714285714 HSPA1B 4.38314057679324 Human Diseases Infectious disease: viral hsa05162 Measles 1/4 136/9376 17.2352941176471 HSPA1B 3.93997188846293 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 1/4 142/9376 16.5070422535211 HSP90AA1 3.84660596944626 Cellular Processes Cell growth and death hsa04217 Necroptosis 1/4 168/9376 13.952380952381 HSP90AA1 3.49962160305821 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 1/4 187/9376 12.5347593582888 HSP90AA1 3.29150644624789 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 1/4 217/9376 10.8018433179724 HSP90AA1 3.01795727613107 Genetic Information Processing Transcription hsa03040 Spliceosome 1/4 243/9376 9.64609053497943 HSPA1B 2.82108181011412 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 1/4 248/9376 9.45161290322581 HSP90AA1 2.78661593397912 Cellular Processes Transport and catabolism hsa04144 Endocytosis 1/4 250/9376 9.376 HSPA1B 2.77310257873735 Human Diseases Neurodegenerative disease hsa05020 Prion disease 1/4 275/9376 8.52363636363636 HSPA1B 2.61606831300753 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 1/4 300/9376 7.81333333333333 HSPA1B 2.47783574874596 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 1/4 323/9376 7.25696594427245 TRIM71 2.36411329901331 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 1/4 362/9376 6.47513812154696 HSP90AA1 2.19477539053578