category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Organismal Systems Immune system hsa04610 Complement and coagulation cascades 2/9 88/9376 23.6767676767677 CFB/SERPINE1 6.62472746107302 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 2/9 140/9376 14.8825396825397 ADCY10/SERPINE1 5.12976667728489 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 2/9 156/9376 13.3561253561254 IFIT1/RSAD2 4.82376094670318 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 2/9 203/9376 10.263820470717 PAK3/LAMA3 4.13608147357203 Human Diseases Cancer: specific types hsa05211 Renal cell carcinoma 1/9 70/9376 14.8825396825397 PAK3 3.61362475156178 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 1/9 75/9376 13.8903703703704 SERPINE1 3.47406418623207 Environmental Information Processing Signal transduction hsa04012 ErbB signaling pathway 1/9 86/9376 12.1136950904393 PAK3 3.2092716447849 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 1/9 89/9376 11.705368289638 LAMA3 3.14532499364837 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 1/9 93/9376 11.2019115890084 LAMA3 3.06468249283534 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 1/9 97/9376 10.7399770904926 ADCY10 2.98882060052968 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/9 99/9376 10.5230078563412 CFB 2.95253187191246 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 1/9 101/9376 10.3146314631463 SERPINE1 2.91726604470436 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 1/9 103/9376 10.1143473570658 SERPINE1 2.88297377095514 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 1/9 103/9376 10.1143473570658 LAMA3 2.88297377095514 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 1/9 110/9376 9.47070707070707 SERPINE1 2.76997909154715 Organismal Systems Endocrine system hsa04914 Progesterone-mediated oocyte maturation 1/9 110/9376 9.47070707070707 SPDYE1 2.76997909154715 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 1/9 112/9376 9.3015873015873 LAMA3 2.73953914472414 Organismal Systems Immune system hsa04660 T cell receptor signaling pathway 1/9 122/9376 8.53916211293261 PAK3 2.59803431229005 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 1/9 122/9376 8.53916211293261 ADCY10 2.59803431229005 Metabolism Nucleotide metabolism hsa00230 Purine metabolism 1/9 128/9376 8.13888888888889 ADCY10 2.52068356432753 Cellular Processes Cell growth and death hsa04114 Oocyte meiosis 1/9 138/9376 7.54911433172303 SPDYE1 2.40236929957327 NA NA hsa04518 Integrin signaling 1/9 154/9376 6.76479076479076 LAMA3 2.2358259029276 Cellular Processes Cell growth and death hsa04218 Cellular senescence 1/9 157/9376 6.63552724699221 SERPINE1 2.20723770020222 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 1/9 157/9376 6.63552724699221 SERPINE1 2.20723770020222 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 1/9 168/9376 6.2010582010582 IFNL1 2.10848410801426 Human Diseases Infectious disease: viral hsa05164 Influenza A 1/9 173/9376 6.0218368657675 RSAD2 2.06646271578531 Organismal Systems Development and regeneration hsa04360 Axon guidance 1/9 184/9376 5.66183574879227 PAK3 1.9795546884665 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 1/9 200/9376 5.20888888888889 PAK3 1.86492937236651 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 1/9 214/9376 4.8681204569055 PAK3 1.77426451051991 NA NA hsa04382 Cornified envelope formation 1/9 217/9376 4.80081925243216 LAMA3 1.75585920004678 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 1/9 226/9376 4.60963618485742 ADCY10 1.70260434327798 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 1/9 232/9376 4.4904214559387 PAK3 1.66863130161123 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 1/9 235/9376 4.43309692671395 ADCY10 1.65207505789514 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 1/9 238/9376 4.37721755368814 PAK3 1.63579385503493 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 1/9 238/9376 4.37721755368814 CFB 1.63579385503493 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 1/9 248/9376 4.20071684587814 PAK3 1.58340463951815 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 1/9 298/9376 3.49589858314691 IFNL1 1.35720862262987 NA NA hsa04517 IgSF CAM signaling 1/9 299/9376 3.4842066146414 PAK3 1.35318997931992 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 1/9 333/9376 3.12846179512846 LAMA3 1.22585285635904 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 1/9 362/9376 2.87783916513198 LAMA3 1.12943315861216