ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0030145 manganese ion binding 2/32 68/18639 0.0294117647058824 17.1314338235294 0.00606125394337319 0.190902519978919 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/32 11/18639 0.0909090909090909 52.9517045454545 0.0187288341576669 0.190902519978919 GO:0043522 leucine zipper domain binding 1/32 11/18639 0.0909090909090909 52.9517045454545 0.0187288341576669 0.190902519978919 GO:0004000 adenosine deaminase activity 1/32 12/18639 0.0833333333333333 48.5390625 0.0204145050459512 0.190902519978919 GO:0005179 hormone activity 2/32 132/18639 0.0151515151515152 8.82528409090909 0.0214912506814883 0.190902519978919 GO:0008035 high-density lipoprotein particle binding 1/32 13/18639 0.0769230769230769 44.8052884615385 0.0220973705550795 0.190902519978919 GO:0030983 mismatched DNA binding 1/32 14/18639 0.0714285714285714 41.6049107142857 0.0237774352035407 0.190902519978919 GO:0042043 neurexin family protein binding 1/32 14/18639 0.0714285714285714 41.6049107142857 0.0237774352035407 0.190902519978919 GO:0030275 LRR domain binding 1/32 16/18639 0.0625 36.404296875 0.0271291799572511 0.190902519978919 GO:0140328 floppase activity 1/32 16/18639 0.0625 36.404296875 0.0271291799572511 0.190902519978919 GO:0008525 phosphatidylcholine transporter activity 1/32 18/18639 0.0555555555555556 32.359375 0.0304697753144734 0.190902519978919 GO:0016854 racemase and epimerase activity 1/32 18/18639 0.0555555555555556 32.359375 0.0304697753144734 0.190902519978919 GO:0034185 apolipoprotein binding 1/32 18/18639 0.0555555555555556 32.359375 0.0304697753144734 0.190902519978919 GO:0005229 intracellularly calcium-gated chloride channel activity 1/32 19/18639 0.0526315789473684 30.65625 0.0321359031910605 0.190902519978919 GO:0046624 sphingolipid transporter activity 1/32 19/18639 0.0526315789473684 30.65625 0.0321359031910605 0.190902519978919 GO:0141147 intracellularly calcium-gated channel activity 1/32 19/18639 0.0526315789473684 30.65625 0.0321359031910605 0.190902519978919 GO:0140664 ATP-dependent DNA damage sensor activity 1/32 20/18639 0.05 29.1234375 0.0337992571705391 0.190902519978919 GO:0051428 peptide hormone receptor binding 1/32 21/18639 0.0476190476190476 27.7366071428571 0.0354598417223706 0.190902519978919 GO:0140103 catalytic activity, acting on a glycoprotein 1/32 23/18639 0.0434782608695652 25.3247282608696 0.0387727203861402 0.190902519978919 GO:0140612 DNA damage sensor activity 1/32 24/18639 0.0416666666666667 24.26953125 0.0404250234022361 0.190902519978919 GO:0120020 cholesterol transfer activity 1/32 25/18639 0.04 23.29875 0.0420745747990201 0.190902519978919 GO:0070006 metalloaminopeptidase activity 1/32 26/18639 0.0384615384615385 22.4026442307692 0.0437213790112492 0.190902519978919 GO:0008320 protein transmembrane transporter activity 1/32 27/18639 0.037037037037037 21.5729166666667 0.0453654404667718 0.190902519978919 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/32 27/18639 0.037037037037037 21.5729166666667 0.0453654404667718 0.190902519978919 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 3/32 484/18639 0.00619834710743802 3.61034349173554 0.049493712621811 0.190902519978919 GO:0031210 phosphatidylcholine binding 1/32 30/18639 0.0333333333333333 19.415625 0.0502812124681551 0.190902519978919 GO:0001216 DNA-binding transcription activator activity 3/32 491/18639 0.00610997963340122 3.55887219959267 0.0512650491012811 0.190902519978919 GO:0005543 phospholipid binding 3/32 497/18639 0.00603621730382294 3.51590794768612 0.0528080580546398 0.190902519978919 GO:0022884 macromolecule transmembrane transporter activity 1/32 32/18639 0.03125 18.2021484375 0.053544760886107 0.190902519978919 GO:0030515 snoRNA binding 1/32 32/18639 0.03125 18.2021484375 0.053544760886107 0.190902519978919 GO:0071813 lipoprotein particle binding 1/32 32/18639 0.03125 18.2021484375 0.053544760886107 0.190902519978919 GO:0071814 protein-lipid complex binding 1/32 32/18639 0.03125 18.2021484375 0.053544760886107 0.190902519978919 GO:0120015 sterol transfer activity 1/32 32/18639 0.03125 18.2021484375 0.053544760886107 0.190902519978919 GO:0019239 deaminase activity 1/32 33/18639 0.0303030303030303 17.6505681818182 0.0551724584005722 0.190902519978919 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/32 34/18639 0.0294117647058824 17.1314338235294 0.05679744396067 0.190902519978919 GO:0051427 hormone receptor binding 1/32 34/18639 0.0294117647058824 17.1314338235294 0.05679744396067 0.190902519978919 GO:0004177 aminopeptidase activity 1/32 40/18639 0.025 14.56171875 0.0664906506878571 0.210424888704468 GO:0050997 quaternary ammonium group binding 1/32 40/18639 0.025 14.56171875 0.0664906506878571 0.210424888704468 GO:0140318 protein transporter activity 1/32 41/18639 0.024390243902439 14.2065548780488 0.0680967746288214 0.210424888704468 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/32 43/18639 0.0232558139534884 13.5457848837209 0.0713009953461422 0.210424888704468 GO:0008375 acetylglucosaminyltransferase activity 1/32 43/18639 0.0232558139534884 13.5457848837209 0.0713009953461422 0.210424888704468 GO:0140303 intramembrane lipid transporter activity 1/32 45/18639 0.0222222222222222 12.94375 0.0744945419349787 0.213612984228605 GO:0099095 ligand-gated monoatomic anion channel activity 1/32 47/18639 0.0212765957446809 12.3929521276596 0.0776774488104018 0.213612984228605 GO:0140359 ABC-type transporter activity 1/32 47/18639 0.0212765957446809 12.3929521276596 0.0776774488104018 0.213612984228605 GO:0031267 small GTPase binding 2/32 283/18639 0.00706713780918728 4.11638692579505 0.084620790301179 0.227535902809837 GO:0015485 cholesterol binding 1/32 54/18639 0.0185185185185185 10.7864583333333 0.0887343294859124 0.233409866691204 GO:0019905 syntaxin binding 1/32 61/18639 0.0163934426229508 9.54866803278689 0.0996627533827071 0.247521555553166 GO:0051020 GTPase binding 2/32 315/18639 0.00634920634920635 3.69821428571429 0.101440128460275 0.247521555553166 GO:0038024 cargo receptor activity 1/32 65/18639 0.0153846153846154 8.96105769230769 0.105850449227312 0.247521555553166 GO:0120013 lipid transfer activity 1/32 65/18639 0.0153846153846154 8.96105769230769 0.105850449227312 0.247521555553166 GO:0008235 metalloexopeptidase activity 1/32 66/18639 0.0151515151515152 8.82528409090909 0.107390924387467 0.247521555553166 GO:0005548 phospholipid transporter activity 1/32 68/18639 0.0147058823529412 8.56571691176471 0.11046416528819 0.247521555553166 GO:0032934 sterol binding 1/32 68/18639 0.0147058823529412 8.56571691176471 0.11046416528819 0.247521555553166 GO:1990841 promoter-specific chromatin binding 1/32 68/18639 0.0147058823529412 8.56571691176471 0.11046416528819 0.247521555553166 GO:0140299 molecular sensor activity 1/32 71/18639 0.0140845070422535 8.20378521126761 0.115054815293094 0.251895910407505 GO:0042379 chemokine receptor binding 1/32 72/18639 0.0138888888888889 8.08984375 0.116579925477853 0.251895910407505 GO:0019003 GDP binding 1/32 75/18639 0.0133333333333333 7.76625 0.121139994275626 0.257156829953521 GO:0048306 calcium-dependent protein binding 1/32 80/18639 0.0125 7.280859375 0.128689482520824 0.268472885948617 GO:0005254 chloride channel activity 1/32 83/18639 0.0120481927710843 7.01769578313253 0.133188979249196 0.271612336391701 GO:0051117 ATPase binding 1/32 84/18639 0.0119047619047619 6.93415178571429 0.134683803169439 0.271612336391701 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/32 86/18639 0.0116279069767442 6.77289244186047 0.137665962801997 0.273075106541667 GO:0043178 alcohol binding 1/32 92/18639 0.0108695652173913 6.33118206521739 0.146552825983625 0.286014386193849 GO:0042626 ATPase-coupled transmembrane transporter activity 1/32 98/18639 0.0102040816326531 5.94355867346939 0.155350938180098 0.298372436822094 GO:0008238 exopeptidase activity 1/32 102/18639 0.00980392156862745 5.71047794117647 0.161167464252756 0.302171334554062 GO:0005253 monoatomic anion channel activity 1/32 103/18639 0.00970873786407767 5.65503640776699 0.162615521713182 0.302171334554062 GO:0000149 SNARE binding 1/32 106/18639 0.00943396226415094 5.49498820754717 0.166945179195117 0.302171334554062 GO:0005496 steroid binding 1/32 108/18639 0.00925925925925926 5.39322916666667 0.169819560888006 0.302171334554062 GO:1902936 phosphatidylinositol bisphosphate binding 1/32 111/18639 0.00900900900900901 5.24746621621622 0.174113126451671 0.302171334554062 GO:0005200 structural constituent of cytoskeleton 1/32 112/18639 0.00892857142857143 5.20061383928571 0.175539528651237 0.302171334554062 GO:0043022 ribosome binding 1/32 112/18639 0.00892857142857143 5.20061383928571 0.175539528651237 0.302171334554062 GO:0035401 histone H3Y41 kinase activity 1/32 115/18639 0.00869565217391304 5.06494565217391 0.17980443047845 0.302171334554062 GO:0140801 histone H2AXY142 kinase activity 1/32 115/18639 0.00869565217391304 5.06494565217391 0.17980443047845 0.302171334554062 GO:1990782 protein tyrosine kinase binding 1/32 117/18639 0.00854700854700855 4.97836538461539 0.182635816293777 0.302725120158178 GO:0004540 RNA nuclease activity 1/32 121/18639 0.00826446280991736 4.81379132231405 0.188270209279261 0.303742604303874 GO:0015108 chloride transmembrane transporter activity 1/32 121/18639 0.00826446280991736 4.81379132231405 0.188270209279261 0.303742604303874 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/32 130/18639 0.00769230769230769 4.48052884615385 0.200810363572497 0.319711236740422 GO:0004713 protein tyrosine kinase activity 1/32 140/18639 0.00714285714285714 4.16049107142857 0.214523768066325 0.337108778389939 GO:0008194 UDP-glycosyltransferase activity 1/32 145/18639 0.00689655172413793 4.01702586206897 0.221294709691817 0.343290511188588 GO:0008509 monoatomic anion transmembrane transporter activity 1/32 149/18639 0.00671140939597315 3.90918624161074 0.226670719243261 0.347179202891576 GO:0015103 inorganic anion transmembrane transporter activity 1/32 165/18639 0.00606060606060606 3.53011363636364 0.247817451685112 0.372142752992324 GO:0015399 primary active transmembrane transporter activity 1/32 166/18639 0.00602409638554217 3.50884789156627 0.249120355308911 0.372142752992324 GO:0043021 ribonucleoprotein complex binding 1/32 177/18639 0.00564971751412429 3.29078389830508 0.263308768920588 0.381201296623788 GO:0005319 lipid transporter activity 1/32 178/18639 0.00561797752808989 3.27229634831461 0.264585668465303 0.381201296623788 GO:0016853 isomerase activity 1/32 180/18639 0.00555555555555556 3.2359375 0.26713303847026 0.381201296623788 GO:0008237 metallopeptidase activity 1/32 184/18639 0.00543478260869565 3.1655910326087 0.272202159519606 0.381201296623788 GO:1901981 phosphatidylinositol phosphate binding 1/32 185/18639 0.00540540540540541 3.14847972972973 0.273464122721739 0.381201296623788 GO:0015276 ligand-gated monoatomic ion channel activity 1/32 186/18639 0.00537634408602151 3.13155241935484 0.274723966011698 0.381201296623788 GO:0022834 ligand-gated channel activity 1/32 188/18639 0.00531914893617021 3.09823803191489 0.277237306635482 0.381201296623788 GO:0016758 hexosyltransferase activity 1/32 197/18639 0.0050761421319797 2.95669416243655 0.288443309820491 0.392153263913251 GO:0004518 nuclease activity 1/32 209/18639 0.00478468899521531 2.78693181818182 0.30312312467316 0.400264201193796 GO:0051015 actin filament binding 1/32 209/18639 0.00478468899521531 2.78693181818182 0.30312312467316 0.400264201193796 GO:0008094 ATP-dependent activity, acting on DNA 1/32 210/18639 0.00476190476190476 2.77366071428571 0.304333111651482 0.400264201193796 GO:0000287 magnesium ion binding 1/32 230/18639 0.00434782608695652 2.53247282608696 0.328109802095406 0.422354106952597 GO:0005085 guanyl-nucleotide exchange factor activity 1/32 230/18639 0.00434782608695652 2.53247282608696 0.328109802095406 0.422354106952597 GO:0003713 transcription coactivator activity 1/32 256/18639 0.00390625 2.2752685546875 0.357845101519982 0.455781655620187 GO:0016757 glycosyltransferase activity 1/32 267/18639 0.00374531835205993 2.1815308988764 0.370037988093297 0.462962520788784 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 1/32 268/18639 0.00373134328358209 2.17339085820896 0.371135243938116 0.462962520788784 GO:0005126 cytokine receptor binding 1/32 275/18639 0.00363636363636364 2.11806818181818 0.378764360287497 0.466896789539607 GO:0001217 DNA-binding transcription repressor activity 1/32 278/18639 0.00359712230215827 2.09521133093525 0.38200646416877 0.466896789539607 GO:0035091 phosphatidylinositol binding 1/32 284/18639 0.00352112676056338 2.0509463028169 0.388441570717084 0.470014300567671 GO:0001664 G protein-coupled receptor binding 1/32 297/18639 0.00336700336700337 1.96117424242424 0.402162383390478 0.481798498913345 GO:0022836 gated channel activity 1/32 318/18639 0.00314465408805031 1.83166273584906 0.423699096532401 0.502623438043338 GO:0003924 GTPase activity 1/32 331/18639 0.00302114803625378 1.75972432024169 0.436652629662628 0.512960856205612 GO:0140097 catalytic activity, acting on DNA 1/32 336/18639 0.00297619047619048 1.73353794642857 0.441559272579116 0.513737230596856 GO:0141003 histone H2AX kinase activity 1/32 354/18639 0.00282485875706215 1.64539194915254 0.458882718700661 0.521507802773941 GO:0140996 histone H3 kinase activity 1/32 357/18639 0.00280112044817927 1.63156512605042 0.46171888124282 0.521507802773941 GO:0035173 histone kinase activity 1/32 360/18639 0.00277777777777778 1.61796875 0.464540640760024 0.521507802773941 GO:0106310 protein serine kinase activity 1/32 361/18639 0.00277008310249307 1.61348684210526 0.465478038839551 0.521507802773941 GO:0046982 protein heterodimerization activity 1/32 369/18639 0.002710027100271 1.57850609756098 0.472920207438517 0.524984817431749 GO:0005525 GTP binding 1/32 378/18639 0.00264550264550265 1.54092261904762 0.481172675435356 0.529289942978891 GO:0140098 catalytic activity, acting on RNA 1/32 387/18639 0.00258397932816537 1.50508720930233 0.489299911271699 0.533380984359239 GO:0019001 guanyl nucleotide binding 1/32 400/18639 0.0025 1.456171875 0.500821886811334 0.536278303576738 GO:0032561 guanyl ribonucleotide binding 1/32 400/18639 0.0025 1.456171875 0.500821886811334 0.536278303576738 GO:0016887 ATP hydrolysis activity 1/32 417/18639 0.00239808153477218 1.39680755395683 0.515509672617361 0.547163775321936 GO:0004674 protein serine/threonine kinase activity 1/32 433/18639 0.0023094688221709 1.34519341801386 0.528950459001944 0.556547874254219 GO:0003779 actin binding 1/32 443/18639 0.00225733634311512 1.31482787810384 0.537166754007214 0.55972600623698 GO:0005216 monoatomic ion channel activity 1/32 448/18639 0.00223214285714286 1.30015345982143 0.541222667187823 0.55972600623698 GO:0022804 active transmembrane transporter activity 1/32 457/18639 0.00218818380743982 1.27454868708972 0.548436708370612 0.562380014515627 GO:0030695 GTPase regulator activity 1/32 489/18639 0.00204498977505112 1.19114263803681 0.573207333812868 0.577702928497085 GO:0060589 nucleoside-triphosphatase regulator activity 1/32 490/18639 0.00204081632653061 1.18871173469388 0.573959805731215 0.577702928497085 GO:0003712 transcription coregulator activity 1/32 495/18639 0.00202020202020202 1.17670454545455 0.577702928497085 0.577702928497085