category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	12/106	238/9376	4.45980656413509	RPS10/RPS21/RPS29/RPL36A/RPS27/RPL17/RPL26/RPL39/ADAM17/RPL41/RPL34/RPL37	5.78113916223449
Genetic Information Processing	Translation	hsa03010	Ribosome	11/106	222/9376	4.38279789223185	RPS10/RPS21/RPS29/RPL36A/RPS27/RPL17/RPL26/RPL39/RPL41/RPL34/RPL37	5.45438498386706
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	4/106	63/9376	5.61605271039233	GTF2H2/ERCC5/CCNH/GTF2H2C	3.93092661635898
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	3/106	44/9376	6.03087478559177	GTF2H2/CCNH/GTF2H2C	3.57668905036195
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	3/106	56/9376	4.73854447439353	MGAT4C/MAGT1/ALG10B	3.00045634599239
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	5/106	157/9376	2.81696911428915	SMAD7/WNT2B/BBC3/CCND3/PPP1CB	2.45501509904161
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	4/106	110/9376	3.21646655231561	SMAD7/GREM1/TFRC/SKIL	2.50040339754921
Metabolism	Lipid metabolism	hsa01040	Biosynthesis of unsaturated fatty acids	2/106	27/9376	6.55206149545772	ACOX1/ELOVL5	3.08924444017087
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	4/106	116/9376	3.05009759271308	PGAM2/HK2/PRPS2/ACOX1	2.37572813378755
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	6/106	226/9376	2.34830522624812	PTCH1/CACNA1F/ACOX1/NFATC1/PPP1CB/ORAI1	2.19396954237962
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	3/106	70/9376	3.79083557951482	HLA-DQA2/CD80/ABL2	2.50611185380727
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	3/106	83/9376	3.19709024778359	EZH2/E2F6/ASXL1	2.14984761655911
Human Diseases	Immune disease	hsa05330	Allograft rejection	2/106	39/9376	4.53604257377842	HLA-DQA2/CD80	2.36616383995927
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	2/106	42/9376	4.21203953279425	TFRC/PRNP	2.2308498085233
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	2/106	44/9376	4.02058319039451	MGAT4C/MAGT1	2.14747678748292
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	2/106	44/9376	4.02058319039451	HLA-DQA2/CD80	2.14747678748292
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	6/106	275/9376	1.92987993138937	PSMA2/CACNA1F/RYR3/PRNP/PSMD11/TUBB4B	1.67358343420151
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	2/106	45/9376	3.93123689727463	ABCG8/ABCC1	2.10761744530986
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	2/106	45/9376	3.93123689727463	HLA-DQA2/CD80	2.10761744530986
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	2/106	46/9376	3.84577522559475	PSMA2/PSMD11	2.06888995952886
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	4/106	154/9376	2.29747610879686	CACNA1F/RYR3/NFATC1/PPP1CB	1.73598462676456
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	3/106	98/9376	2.70773969965345	CACNA1F/PRKD3/ORAI1	1.81721466132442
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	4/106	157/9376	2.25357529143132	ADAM17/DUSP8/NFATC1/S1PR1	1.69378017713493
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	2/106	50/9376	3.53811320754717	HLA-DQA2/CD80	1.92418572941652
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	3/106	105/9376	2.52722371967655	USP30/GABARAP/ARIH1	1.68280085238118
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	2/106	54/9376	3.27603074772886	HLA-DQA2/CD80	1.7935734197538
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	3/106	109/9376	2.43448156482603	HLA-DQA2/IL27RA/NFATC1	1.6107841314257
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	2/106	57/9376	3.10360807679576	ACOX1/ELOVL5	1.70339867600199
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	4/106	178/9376	1.9877040491838	WNT2B/CCND3/RYK/NFATC1	1.42261975934953
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	7/106	388/9376	1.59579848278545	PSMA2/CACNA1F/RYR3/WNT2B/ADAM17/PSMD11/TUBB4B	1.28168832296903
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	2/106	63/9376	2.80802635519617	PTCH1/WNT2B	1.53967455933038
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	2/106	65/9376	2.72162554426705	CACNA1F/ORAI1	1.48934707406211
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	3/106	125/9376	2.1228679245283	ABCC1/S1PR1/S1PR3	1.35141285547238
Organismal Systems	Immune system	hsa04611	Platelet activation	3/106	126/9376	2.10601976639712	F2RL3/PPP1CB/ORAI1	1.33652165111447
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	2/106	66/9376	2.68038879359634	HLA-DQA2/NFATC1	1.46489200125733
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	2/106	67/9376	2.64038299070684	PGAM2/HK2	1.44088674877609
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	8/106	480/9376	1.47421383647799	PSMA2/CACNA1F/RYR3/WNT2B/IFT57/PRNP/PSMD11/TUBB4B	1.14050227752666
NA	NA	hsa03273	Virion - Lassa virus and SFTS virus	1/106	17/9376	5.2031076581576	TFRC	1.85472256168215
Organismal Systems	Endocrine system	hsa04924	Renin secretion	2/106	69/9376	2.5638501503965	CACNA1F/ORAI1	1.3941629218792
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	2/106	71/9376	2.49162901939942	PGAM2/HK2	1.34905766329445
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	4/106	204/9376	1.73436921938587	PTCH1/WNT2B/DDX5/PPP1CB	1.13395606931433
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	2/106	73/9376	2.42336521064875	APOBEC3H/ELL2	1.30546421058697
Metabolism	Lipid metabolism	hsa00100	Steroid biosynthesis	1/106	20/9376	4.42264150943396	CYP51A1	1.63843798573871
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	2/106	75/9376	2.35874213836478	PGAM2/PRPS2	1.26328563445678
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/106	75/9376	2.35874213836478	BBC3/CCND3	1.26328563445678
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	3/106	142/9376	1.86872176454956	JUND/CYLD/NFATC1	1.11539487097875
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	4/106	212/9376	1.6689213243147	FARP2/F2RL3/SIPA1L1/PRKD3	1.05341411880088
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	2/106	78/9376	2.26802128688921	IMPA1/PI4K2B	1.20247976938086
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	2/106	78/9376	2.26802128688921	ARHGEF26/DNM2	1.20247976938086
Metabolism	Metabolism of terpenoids and polyketides	hsa00900	Terpenoid backbone biosynthesis	1/106	23/9376	3.84577522559475	IDI1	1.46112626896624
Metabolism	Glycan biosynthesis and metabolism	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	1/106	24/9376	3.68553459119497	NDST2	1.40858424415427
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	5/106	300/9376	1.47421383647799	JUND/CACNA1F/DUSP8/MAP3K6/NFATC1	0.892660482084925
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	3/106	155/9376	1.71199026171637	HLA-DQA2/TFRC/TUBB4B	0.955761638967582
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	3/106	155/9376	1.71199026171637	CACNA1F/WNT2B/ORAI1	0.955761638967582
Metabolism	Lipid metabolism	hsa00592	alpha-Linolenic acid metabolism	1/106	26/9376	3.40203193033382	ACOX1	1.31146996376435
Organismal Systems	Digestive system	hsa04977	Vitamin digestion and absorption	1/106	26/9376	3.40203193033382	ABCC1	1.31146996376435
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	3/106	157/9376	1.69018146857349	CCND3/NFATC1/PPP1CB	0.932545255228252
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/106	89/9376	1.9877040491838	CACNA1F/GABARAP	1.00111234890764
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	5/106	308/9376	1.43592256799804	PSMA2/BBC3/IFT57/PSMD11/TUBB4B	0.831816746633133
Metabolism	Lipid metabolism	hsa00062	Fatty acid elongation	1/106	28/9376	3.15902964959569	ELOVL5	1.22342393860992
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	1/106	28/9376	3.15902964959569	GCH1	1.22342393860992
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	2/106	93/9376	1.90221140190708	HLA-DQA2/NFATC1	0.934984290795685
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/106	94/9376	1.88197511039743	JUND/MAPK6	0.918963321768187
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/106	30/9376	2.94842767295597	ABCC1	1.14295921088246
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	3/106	166/9376	1.59854512389179	CACNA1F/NFATC1/PPP1CB	0.831993301642806
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/106	95/9376	1.86216484607746	HLA-DQA2/CD80	0.903136575902567
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/106	31/9376	2.85331710286062	PRPS2	1.10519683198492
Metabolism	Metabolism of other amino acids	hsa00410	beta-Alanine metabolism	1/106	31/9376	2.85331710286062	ACOX1	1.10519683198492
NA	NA	hsa04981	Folate transport and metabolism	1/106	31/9376	2.85331710286062	ABCC1	1.10519683198492
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	2/106	98/9376	1.80515979976896	IMPA1/PI4K2B	0.856774714053972
Metabolism	Carbohydrate metabolism	hsa00052	Galactose metabolism	1/106	32/9376	2.76415094339623	HK2	1.06891462533072
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/106	32/9376	2.76415094339623	ACOX1	1.06891462533072
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	1/106	32/9376	2.76415094339623	GABARAP	1.06891462533072
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/106	32/9376	2.76415094339623	BBC3	1.06891462533072
Human Diseases	Immune disease	hsa05310	Asthma	1/106	32/9376	2.76415094339623	HLA-DQA2	1.06891462533072
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/106	100/9376	1.76905660377359	HLA-DQA2/TFRC	0.82675463719122
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	4/106	250/9376	1.41524528301887	TFRC/VPS26A/DNM2/IST1	0.711595484658602
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	1/106	33/9376	2.68038879359634	STX5	1.03400413584927
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	3/106	174/9376	1.52504879635654	FBXO2/ERO1A/MAGT1	0.747535601203225
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/106	101/9376	1.75154119185503	COL4A4/NFATC1	0.811998488264521
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/106	34/9376	2.6015538290788	RORB	1.00036795381638
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	4/106	254/9376	1.39295795572723	CACNA1F/RYR3/NFATC1/ORAI1	0.678916891259137
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/106	103/9376	1.71753068327532	COL4A4/SERPINB9	0.78297458171563
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	1/106	35/9376	2.52722371967655	HK2	0.967918298922329
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	3/106	180/9376	1.47421383647799	HLA-DQA2/SRSF3/PPP1CB	0.686925591798241
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	2/106	105/9376	1.6848158131177	CYLD/NFATC1	0.754577485401185
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/106	36/9376	2.45702306079665	HK2	0.936575820785336
Metabolism	Global and overview maps	hsa01250	Biosynthesis of nucleotide sugars	1/106	37/9376	2.39061703212647	HK2	0.906268577794447
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	2/106	108/9376	1.63801537386443	XPO4/NUP58	0.713097169688728
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	1/106	38/9376	2.32770605759682	HK2	0.876931163714882
Human Diseases	Immune disease	hsa05340	Primary immunodeficiency	1/106	38/9376	2.32770605759682	ORAI1	0.876931163714882
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	2/106	110/9376	1.6082332761578	HK2/TFRC	0.686150011430854
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	4/106	268/9376	1.32019149535342	PSMA2/RYR3/PSMD11/TUBB4B	0.568675321989939
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	1/106	41/9376	2.15738610216291	PGAM2	0.794166811966564
Genetic Information Processing	Replication and repair	hsa03440	Homologous recombination	1/106	41/9376	2.15738610216291	SYCP3	0.794166811966564
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	2/106	115/9376	1.5383100902379	JUND/WNK3	0.621085231196756
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/106	43/9376	2.05704256252742	ACOX1	0.742873341105367
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/106	43/9376	2.05704256252742	ABCG8	0.742873341105367
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/106	119/9376	1.48660218804503	ADAM17/CYLD	0.57123013452535
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	5/106	368/9376	1.20180475799836	PSMA2/SRSF3/PSMD11/NUP58/TUBB4B	0.422318227107734
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	3/106	203/9376	1.30718468259132	COL4A4/CCND3/PPP1CB	0.473140998729195
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	3/106	205/9376	1.29443166129775	HLA-DQA2/CCND3/PSMD11	0.455776361418693
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	3/106	205/9376	1.29443166129775	GTF2H2/CCND3/GTF2H2C	0.455776361418693
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/106	47/9376	1.88197511039743	HK2	0.648166252972358
NA	NA	hsa03272	Virion - Hepatitis viruses	1/106	48/9376	1.84276729559748	IST1	0.625940032051801
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/106	48/9376	1.84276729559748	HK2	0.625940032051801
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	2/106	128/9376	1.38207547169811	PRPS2/ADK	0.465402740196465
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/106	50/9376	1.76905660377359	AMD1	0.583034569811309
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/106	51/9376	1.73436921938587	TMEM86B	0.562307449304359
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/106	51/9376	1.73436921938587	ERO1A	0.562307449304359
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	2/106	133/9376	1.33011774719818	GABARAP/S1PR1	0.410002892349493
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/106	52/9376	1.70101596516691	ABCG8	0.542034777239295
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	2/106	134/9376	1.32019149535342	CACNA1F/PPP1CB	0.399188400537484
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/106	53/9376	1.6689213243147	DNM2	0.522196356544684
Human Diseases	Infectious disease: viral	hsa05162	Measles	2/106	136/9376	1.3007769145394	BBC3/CCND3	0.377812804210946
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/106	54/9376	1.63801537386443	AMD1	0.502773267496229
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	2/106	137/9376	1.29128219253546	BBC3/CTSH	0.367248845111608
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	2/106	138/9376	1.28192507519825	STAG3/PPP1CB	0.356765600580322
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	2/106	138/9376	1.28192507519825	HK2/PPP1CB	0.356765600580322
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	3/106	224/9376	1.18463611859838	HLA-DQA2/CCND3/NFATC1	0.299075866092257
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/106	56/9376	1.57951482479784	PTCH1	0.465103182688077
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/106	56/9376	1.57951482479784	EEF1G	0.465103182688077
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/106	143/9376	1.23710252012139	HLA-DQA2/CD80	0.305514252146044
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	2/106	144/9376	1.22851153039832	WNT2B/SKIL	0.295488219266321
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	2/106	144/9376	1.22851153039832	PSMA2/PSMD11	0.295488219266321
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/106	62/9376	1.42665855143031	ADAM17	0.360418343454417
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/106	63/9376	1.40401317759808	EZH2	0.344048530816081
Genetic Information Processing	Transcription	hsa03040	Spliceosome	3/106	243/9376	1.09201024924295	SRSF3/DDX5/BCAS2	0.155392952652472
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	2/106	154/9376	1.14873805439843	CACNA1F/PPP1CB	0.199007113965267
NA	NA	hsa04518	Integrin signaling	2/106	154/9376	1.14873805439843	COL4A4/CCND3	0.199007113965267
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/106	65/9376	1.36081277213353	GPAT4	0.312132593670409
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/106	65/9376	1.36081277213353	CACNA1F	0.312132593670409
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/106	67/9376	1.32019149535342	PPP1CB	0.281251198859813
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	3/106	248/9376	1.06999391357273	ARHGEF26/DNM2/TUBB4B	0.11945298462015
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	2/106	158/9376	1.11965607833771	CCNH/CCND3	0.162197314871814
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/106	160/9376	1.10566037735849	HLA-DQA2/CD80	0.144145012270146
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/106	69/9376	1.28192507519825	PPP1CB	0.251334494222321
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/106	71/9376	1.24581450969971	ADAM17	0.222319319178223
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/106	72/9376	1.22851153039832	CYLD	0.208131694488332
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/106	168/9376	1.05300988319856	IL27RA/CCND3	0.0741357245870568
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	2/106	169/9376	1.04677905548733	WDR45B/GABARAP	0.065619729115236
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/106	75/9376	1.17937106918239	BBC3	0.166769608844229
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/106	76/9376	1.16385302879841	ACOX1	0.1533622598061
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	2/106	173/9376	1.02257607154542	HLA-DQA2/CCND3	0.0320483309709872
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/106	78/9376	1.13401064344461	CNOT9	0.127083897794162
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/106	78/9376	1.13401064344461	HLA-DQA2	0.127083897794162
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/106	79/9376	1.11965607833771	DNM2	0.114202496784968
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	4/106	370/9376	0.956246812850586	CHRNA5/F2RL3/S1PR1/S1PR3	-0.0918212685977765
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/106	82/9376	1.07869305108145	HLA-DQA2	0.0765315800861905
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/106	83/9376	1.0656967492612	ACOX1	0.0642841139353941
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	2/106	184/9376	0.961443806398687	PTCH1/RYK	-0.0564802694250136
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/106	85/9376	1.04062153163152	ADK	0.0402284436496541
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/106	86/9376	1.02852128126371	ABL2	0.0284124774368366
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/106	86/9376	1.02852128126371	CACNA1F	0.0284124774368366
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/106	86/9376	1.02852128126371	CACNA1F	0.0284124774368366
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	1/106	87/9376	1.01669919757103	CACNA1F	0.0167328320340787
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/106	87/9376	1.01669919757103	BBC3	0.0167328320340787
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	1/106	88/9376	1.00514579759863	F2RL3	0.00518598953947984
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/106	89/9376	0.993852024591902	COL4A4	-0.0062314355265768
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/106	89/9376	0.993852024591902	TUBB4B	-0.0062314355265768
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/106	90/9376	0.982809224318658	ABCG8	-0.0175227026846701
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/106	90/9376	0.982809224318658	NFATC1	-0.0175227026846701
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/106	91/9376	0.972009122952519	NFATC1	-0.0286909515746787
Cellular Processes	Cell motility	hsa04814	Motor proteins	2/106	194/9376	0.911884847305972	KIF18B/TUBB4B	-0.132611602341964
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/106	93/9376	0.95110570095354	FARP2	-0.0506703876954711
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/106	93/9376	0.95110570095354	CACNA1F	-0.0506703876954711
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/106	93/9376	0.95110570095354	RYR3	-0.0506703876954711
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/106	93/9376	0.95110570095354	COL4A4	-0.0506703876954711
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/106	201/9376	0.880127663568948	DDX5/SS18	-0.183701484659469
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/106	97/9376	0.911884847305972	RYR3	-0.093279150370263
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/106	98/9376	0.902579899884482	DNM2	-0.103665233216478
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/106	99/9376	0.89346293119878	PPP1CB	-0.113949721072948
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/106	99/9376	0.89346293119878	HLA-DQA2	-0.113949721072948
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/106	99/9376	0.89346293119878	CACNA1F	-0.113949721072948
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/106	101/9376	0.875770595927517	WNT2B	-0.134222966615935
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/106	103/9376	0.858765341637662	PPP1CB	-0.154116263084695
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	1/106	103/9376	0.858765341637662	COL4A4	-0.154116263084695
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/106	104/9376	0.850507982583454	GPAT4	-0.163925555756642
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/106	105/9376	0.84240790655885	CYLD	-0.173645881578808
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/106	105/9376	0.84240790655885	CACNA1F	-0.173645881578808
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	2/106	214/9376	0.82666196438018	APOBEC3H/NFATC1	-0.274286427054201
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/106	107/9376	0.82666196438018	PGAM2	-0.192827078815811
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	2/106	216/9376	0.819007686932215	ERO1A/NFATC1	-0.287765001295352
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	2/106	217/9376	0.815233457960177	CACNA1F/CCND3	-0.294461060668896
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/106	109/9376	0.811493854942011	CD80	-0.21167417872844
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/106	109/9376	0.811493854942011	PPP1CB	-0.21167417872844
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/106	112/9376	0.789757412398922	HLA-DQA2	-0.239347631921667
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	2/106	227/9376	0.779320089768099	ABL2/PRKD3	-0.359904782072013
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/106	115/9376	0.76915504511895	CACNA1F	-0.266341639833537
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/106	115/9376	0.76915504511895	CACNA1F	-0.266341639833537
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	3/106	333/9376	0.796872344042155	COL4A4/WNT2B/CCND3	-0.403583694816401
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/106	117/9376	0.756007095629737	SS18	-0.283979368612249
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/106	122/9376	0.725023198267863	NFATC1	-0.326896241936374
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/106	122/9376	0.725023198267863	CACNA1F	-0.326896241936374
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/106	130/9376	0.680406386066763	COL4A4	-0.392366145469038
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	2/106	250/9376	0.707622641509434	VPS26A/CTSH	-0.501039786907929
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/106	133/9376	0.665058873599092	NFATC1	-0.415993480376946
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/106	133/9376	0.665058873599092	PPP1CB	-0.415993480376946
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	1/106	138/9376	0.640962537599125	LHPP	-0.454348432164853
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/106	138/9376	0.640962537599125	NFATC1	-0.454348432164853
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/106	140/9376	0.631805929919138	RYR3	-0.469350785688446
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/106	142/9376	0.622907254849854	FBXO2	-0.484168039742688
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/106	144/9376	0.614255765199161	ACOX1	-0.498805801330303
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/106	148/9376	0.597654258031617	WNT2B	-0.527564031156547
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/106	149/9376	0.59364315562872	DNM2	-0.534649489821488
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	1/106	149/9376	0.59364315562872	CACNA1F	-0.534649489821488
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/106	150/9376	0.589685534591195	WNT2B	-0.541694512626024
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/106	154/9376	0.574369027199216	GCH1	-0.56948164243438
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/106	158/9376	0.559828039168856	WNT2B	-0.596665970676153
NA	NA	hsa04519	Cadherin signaling	3/106	404/9376	0.656827946945638	WNT2B/RYK/PPP1CB	-0.753974515345178
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/106	163/9376	0.542655399930548	NFATC1	-0.629847668476374
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/106	168/9376	0.526504941599281	CYLD	-0.66219537046405
NA	NA	hsa04517	IgSF CAM signaling	2/106	299/9376	0.591657727014577	CD80/TUBB4B	-0.767339353938919
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/106	170/9376	0.52031076581576	WNT2B	-0.674912778157319
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	1/106	181/9376	0.488689669550714	HLA-DQA2	-0.742756894334075
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	1/106	183/9376	0.483348798845242	GNL3L	-0.754732517660737
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	1/106	187/9376	0.473009787105237	GABARAP	-0.778373301347359
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	2/106	323/9376	0.547695542963958	EZH2/ABCC1	-0.884574818652661
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/106	191/9376	0.463103822977378	PPP1CB	-0.801615523136054
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/106	196/9376	0.451289949942241	NFATC1	-0.83013421374518
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/106	200/9376	0.442264150943396	TUBB4B	-0.852541559891121
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	1/106	205/9376	0.431477220432582	PPP1CB	-0.88006582822234
NA	NA	hsa04382	Cornified envelope formation	1/106	217/9376	0.407616728980089	COL4A4	-0.944076802982206
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	2/106	362/9376	0.488689669550714	COL4A4/CCND3	-1.06091057741818
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/106	227/9376	0.38966004488405	NFATC1	-0.995397670340786
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	1/106	232/9376	0.381262199089135	PPP1CB	-1.02042534502271
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	1/106	233/9376	0.379625880638108	COL4A4	-1.02538267696445
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	1/106	235/9376	0.376395022079486	COX16	-1.03525027301657
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/106	238/9376	0.371650547011257	ABL2	-1.04993604784085
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	1/106	253/9376	0.349615929599523	HK2	-1.12139863371659
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/106	298/9376	0.29682157781436	IL27RA	-1.31909866877969