ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0034987 immunoglobulin receptor binding 5/235 19/18639 0.263157894736842 20.8723404255319 3.0733053253818e-06 0.00166573148635694 GO:0003735 structural constituent of ribosome 11/235 175/18639 0.0628571428571429 4.9855075987842 1.41586657475575e-05 0.00383699841758807 GO:0140693 molecular condensate scaffold activity 4/235 48/18639 0.0833333333333333 6.60957446808511 0.00310327670881014 0.560658658725032 GO:0030145 manganese ion binding 4/235 68/18639 0.0588235294117647 4.66558197747184 0.0106867400990112 0.669751055960293 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/235 15/18639 0.133333333333333 10.5753191489362 0.0149172056748786 0.669751055960293 GO:0005521 lamin binding 2/235 16/18639 0.125 9.91436170212766 0.0169080315395397 0.669751055960293 GO:0045125 bioactive lipid receptor activity 2/235 17/18639 0.117647058823529 9.33116395494368 0.0190050105526521 0.669751055960293 GO:0030165 PDZ domain binding 4/235 83/18639 0.0481927710843374 3.82240451166368 0.0208563604132408 0.669751055960293 GO:0046624 sphingolipid transporter activity 2/235 19/18639 0.105263157894737 8.34893617021277 0.0235056079359154 0.669751055960293 GO:0015095 magnesium ion transmembrane transporter activity 2/235 20/18639 0.1 7.93148936170213 0.0259034589038811 0.669751055960293 GO:0000287 magnesium ion binding 7/235 230/18639 0.0304347826086957 2.41393154486587 0.0269645980790986 0.669751055960293 GO:0016860 intramolecular oxidoreductase activity 3/235 53/18639 0.0566037735849057 4.48952228020875 0.0292074534083089 0.669751055960293 GO:0008649 rRNA methyltransferase activity 2/235 22/18639 0.0909090909090909 7.21044487427466 0.0309802647718852 0.669751055960293 GO:0140517 protein-RNA adaptor activity 2/235 22/18639 0.0909090909090909 7.21044487427466 0.0309802647718852 0.669751055960293 GO:0140102 catalytic activity, acting on a rRNA 2/235 23/18639 0.0869565217391304 6.89694727104533 0.0336537826445361 0.669751055960293 GO:0048027 mRNA 5'-UTR binding 2/235 24/18639 0.0833333333333333 6.60957446808511 0.0364138409966321 0.669751055960293 GO:0016866 intramolecular transferase activity 2/235 28/18639 0.0714285714285714 5.66534954407295 0.0482684977856137 0.669751055960293 GO:0046625 sphingolipid binding 2/235 28/18639 0.0714285714285714 5.66534954407295 0.0482684977856137 0.669751055960293 GO:0051019 mitogen-activated protein kinase binding 2/235 28/18639 0.0714285714285714 5.66534954407295 0.0482684977856137 0.669751055960293 GO:0003785 actin monomer binding 2/235 29/18639 0.0689655172413793 5.46999266324285 0.0514234596024911 0.669751055960293 GO:1990841 promoter-specific chromatin binding 3/235 68/18639 0.0441176470588235 3.49918648310388 0.054557447711645 0.669751055960293 GO:0031624 ubiquitin conjugating enzyme binding 2/235 30/18639 0.0666666666666667 5.28765957446808 0.0546501872948875 0.669751055960293 GO:0048019 receptor antagonist activity 2/235 30/18639 0.0666666666666667 5.28765957446808 0.0546501872948875 0.669751055960293 GO:0072349 modified amino acid transmembrane transporter activity 2/235 31/18639 0.0645161290322581 5.11708991077557 0.0579463870244664 0.669751055960293 GO:0015035 protein-disulfide reductase activity 2/235 34/18639 0.0588235294117647 4.66558197747184 0.0682295652670915 0.669751055960293 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/235 34/18639 0.0588235294117647 4.66558197747184 0.0682295652670915 0.669751055960293 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 4/235 122/18639 0.0327868852459016 2.60048831531217 0.0686873965563926 0.669751055960293 GO:0003725 double-stranded RNA binding 3/235 75/18639 0.04 3.17259574468085 0.0690334615768264 0.669751055960293 GO:0003823 antigen binding 5/235 174/18639 0.028735632183908 2.27916360968452 0.069680515597448 0.669751055960293 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/235 36/18639 0.0555555555555556 4.4063829787234 0.0753923578068516 0.669751055960293 GO:0016853 isomerase activity 5/235 180/18639 0.0277777777777778 2.2031914893617 0.0780005168684622 0.669751055960293 GO:0046332 SMAD binding 3/235 79/18639 0.0379746835443038 3.0119579854565 0.0780059965086122 0.669751055960293 GO:0005109 frizzled binding 2/235 38/18639 0.0526315789473684 4.17446808510638 0.0827817829463657 0.669751055960293 GO:0000217 DNA secondary structure binding 2/235 39/18639 0.0512820512820513 4.06743044189853 0.0865565380028133 0.669751055960293 GO:0015036 disulfide oxidoreductase activity 2/235 40/18639 0.05 3.96574468085106 0.0903820984424698 0.669751055960293 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/235 40/18639 0.05 3.96574468085106 0.0903820984424698 0.669751055960293 GO:0061791 GTPase motor activity 2/235 40/18639 0.05 3.96574468085106 0.0903820984424698 0.669751055960293 GO:0071949 FAD binding 2/235 40/18639 0.05 3.96574468085106 0.0903820984424698 0.669751055960293 GO:1990606 membrane scission GTPase motor activity 2/235 40/18639 0.05 3.96574468085106 0.0903820984424698 0.669751055960293 GO:0019894 kinesin binding 2/235 42/18639 0.0476190476190476 3.77689969604863 0.0981782027178323 0.669751055960293 GO:0048487 beta-tubulin binding 2/235 42/18639 0.0476190476190476 3.77689969604863 0.0981782027178323 0.669751055960293 GO:0140767 enzyme-substrate adaptor activity 4/235 139/18639 0.0287769784172662 2.28244298178479 0.099232350062142 0.669751055960293 GO:0004197 cysteine-type endopeptidase activity 3/235 88/18639 0.0340909090909091 2.703916827853 0.099918070492881 0.669751055960293 GO:0030547 signaling receptor inhibitor activity 2/235 44/18639 0.0454545454545455 3.60522243713733 0.106155612863251 0.669751055960293 GO:0140359 ABC-type transporter activity 2/235 47/18639 0.0425531914893617 3.37510185604346 0.118431460206149 0.669751055960293 GO:0005528 FK506 binding 1/235 10/18639 0.1 7.93148936170213 0.119188919070305 0.669751055960293 GO:0008190 eukaryotic initiation factor 4E binding 1/235 10/18639 0.1 7.93148936170213 0.119188919070305 0.669751055960293 GO:0008519 ammonium channel activity 1/235 10/18639 0.1 7.93148936170213 0.119188919070305 0.669751055960293 GO:0015279 store-operated calcium channel activity 1/235 10/18639 0.1 7.93148936170213 0.119188919070305 0.669751055960293 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/235 10/18639 0.1 7.93148936170213 0.119188919070305 0.669751055960293 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/235 10/18639 0.1 7.93148936170213 0.119188919070305 0.669751055960293 GO:0016868 intramolecular phosphotransferase activity 1/235 10/18639 0.1 7.93148936170213 0.119188919070305 0.669751055960293 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/235 10/18639 0.1 7.93148936170213 0.119188919070305 0.669751055960293 GO:0032395 MHC class II receptor activity 1/235 10/18639 0.1 7.93148936170213 0.119188919070305 0.669751055960293 GO:0033204 ribonuclease P RNA binding 1/235 10/18639 0.1 7.93148936170213 0.119188919070305 0.669751055960293 GO:0035256 G protein-coupled glutamate receptor binding 1/235 10/18639 0.1 7.93148936170213 0.119188919070305 0.669751055960293 GO:0042975 peroxisome proliferator activated receptor binding 1/235 10/18639 0.1 7.93148936170213 0.119188919070305 0.669751055960293 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/235 10/18639 0.1 7.93148936170213 0.119188919070305 0.669751055960293 GO:0045322 unmethylated CpG binding 1/235 10/18639 0.1 7.93148936170213 0.119188919070305 0.669751055960293 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/235 48/18639 0.0416666666666667 3.30478723404255 0.122599385310288 0.669751055960293 GO:0005536 D-glucose binding 1/235 11/18639 0.0909090909090909 7.21044487427466 0.130300122249138 0.669751055960293 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/235 11/18639 0.0909090909090909 7.21044487427466 0.130300122249138 0.669751055960293 GO:0019206 nucleoside kinase activity 1/235 11/18639 0.0909090909090909 7.21044487427466 0.130300122249138 0.669751055960293 GO:0019215 intermediate filament binding 1/235 11/18639 0.0909090909090909 7.21044487427466 0.130300122249138 0.669751055960293 GO:0034713 type I transforming growth factor beta receptor binding 1/235 11/18639 0.0909090909090909 7.21044487427466 0.130300122249138 0.669751055960293 GO:0070697 activin receptor binding 1/235 11/18639 0.0909090909090909 7.21044487427466 0.130300122249138 0.669751055960293 GO:1990948 ubiquitin ligase inhibitor activity 1/235 11/18639 0.0909090909090909 7.21044487427466 0.130300122249138 0.669751055960293 GO:0045296 cadherin binding 7/235 334/18639 0.0209580838323353 1.66228818957829 0.130620553439408 0.669751055960293 GO:0030544 Hsp70 protein binding 2/235 51/18639 0.0392156862745098 3.11038798498123 0.135309009670869 0.669751055960293 GO:0004126 cytidine deaminase activity 1/235 12/18639 0.0833333333333333 6.60957446808511 0.141271749437857 0.669751055960293 GO:0004526 ribonuclease P activity 1/235 12/18639 0.0833333333333333 6.60957446808511 0.141271749437857 0.669751055960293 GO:0005049 nuclear export signal receptor activity 1/235 12/18639 0.0833333333333333 6.60957446808511 0.141271749437857 0.669751055960293 GO:0005095 GTPase inhibitor activity 1/235 12/18639 0.0833333333333333 6.60957446808511 0.141271749437857 0.669751055960293 GO:0005527 macrolide binding 1/235 12/18639 0.0833333333333333 6.60957446808511 0.141271749437857 0.669751055960293 GO:0016801 hydrolase activity, acting on ether bonds 1/235 12/18639 0.0833333333333333 6.60957446808511 0.141271749437857 0.669751055960293 GO:0016803 ether hydrolase activity 1/235 12/18639 0.0833333333333333 6.60957446808511 0.141271749437857 0.669751055960293 GO:0017166 vinculin binding 1/235 12/18639 0.0833333333333333 6.60957446808511 0.141271749437857 0.669751055960293 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/235 12/18639 0.0833333333333333 6.60957446808511 0.141271749437857 0.669751055960293 GO:0035197 siRNA binding 1/235 12/18639 0.0833333333333333 6.60957446808511 0.141271749437857 0.669751055960293 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/235 12/18639 0.0833333333333333 6.60957446808511 0.141271749437857 0.669751055960293 GO:0097371 MDM2/MDM4 family protein binding 1/235 12/18639 0.0833333333333333 6.60957446808511 0.141271749437857 0.669751055960293 GO:1990817 poly(A) RNA polymerase activity 1/235 12/18639 0.0833333333333333 6.60957446808511 0.141271749437857 0.669751055960293 GO:0016251 RNA polymerase II general transcription initiation factor activity 2/235 53/18639 0.0377358490566038 2.9930148534725 0.143938610552681 0.669751055960293 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/235 54/18639 0.037037037037037 2.93758865248227 0.148296027895492 0.669751055960293 GO:0140463 chromatin-protein adaptor activity 2/235 54/18639 0.037037037037037 2.93758865248227 0.148296027895492 0.669751055960293 GO:0003964 RNA-directed DNA polymerase activity 1/235 13/18639 0.0769230769230769 6.10114566284779 0.152105546553984 0.669751055960293 GO:0005172 vascular endothelial growth factor receptor binding 1/235 13/18639 0.0769230769230769 6.10114566284779 0.152105546553984 0.669751055960293 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/235 13/18639 0.0769230769230769 6.10114566284779 0.152105546553984 0.669751055960293 GO:0035673 oligopeptide transmembrane transporter activity 1/235 13/18639 0.0769230769230769 6.10114566284779 0.152105546553984 0.669751055960293 GO:0004843 cysteine-type deubiquitinase activity 3/235 108/18639 0.0277777777777778 2.2031914893617 0.155894390331374 0.669751055960293 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 4/235 167/18639 0.0239520958083832 1.89975793094662 0.16054524889735 0.669751055960293 GO:0004705 JUN kinase activity 1/235 14/18639 0.0714285714285714 5.66534954407295 0.162803237768406 0.669751055960293 GO:0008195 phosphatidate phosphatase activity 1/235 14/18639 0.0714285714285714 5.66534954407295 0.162803237768406 0.669751055960293 GO:0008331 high voltage-gated calcium channel activity 1/235 14/18639 0.0714285714285714 5.66534954407295 0.162803237768406 0.669751055960293 GO:0008559 ABC-type xenobiotic transporter activity 1/235 14/18639 0.0714285714285714 5.66534954407295 0.162803237768406 0.669751055960293 GO:0042813 Wnt receptor activity 1/235 14/18639 0.0714285714285714 5.66534954407295 0.162803237768406 0.669751055960293 GO:0043176 amine binding 1/235 14/18639 0.0714285714285714 5.66534954407295 0.162803237768406 0.669751055960293 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/235 14/18639 0.0714285714285714 5.66534954407295 0.162803237768406 0.669751055960293 GO:1902936 phosphatidylinositol bisphosphate binding 3/235 111/18639 0.027027027027027 2.14364577343301 0.165005263936446 0.669751055960293 GO:0061980 regulatory RNA binding 2/235 58/18639 0.0344827586206897 2.73499633162142 0.165977865231885 0.669751055960293 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/235 15/18639 0.0666666666666667 5.28765957446808 0.173366525775086 0.669751055960293 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/235 15/18639 0.0666666666666667 5.28765957446808 0.173366525775086 0.669751055960293 GO:0034483 heparan sulfate sulfotransferase activity 1/235 15/18639 0.0666666666666667 5.28765957446808 0.173366525775086 0.669751055960293 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/235 15/18639 0.0666666666666667 5.28765957446808 0.173366525775086 0.669751055960293 GO:0061578 K63-linked deubiquitinase activity 1/235 15/18639 0.0666666666666667 5.28765957446808 0.173366525775086 0.669751055960293 GO:0001664 G protein-coupled receptor binding 6/235 297/18639 0.0202020202020202 1.60232108317215 0.173680162924755 0.669751055960293 GO:0003712 transcription coregulator activity 9/235 495/18639 0.0181818181818182 1.44208897485493 0.174694243373263 0.669751055960293 GO:0001221 transcription coregulator binding 3/235 115/18639 0.0260869565217391 2.0690841813136 0.177390550727294 0.669751055960293 GO:0101005 deubiquitinase activity 3/235 115/18639 0.0260869565217391 2.0690841813136 0.177390550727294 0.669751055960293 GO:0015026 coreceptor activity 2/235 61/18639 0.0327868852459016 2.60048831531217 0.179467746832089 0.669751055960293 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/235 16/18639 0.0625 4.95718085106383 0.183797092057456 0.669751055960293 GO:0004707 MAP kinase activity 1/235 16/18639 0.0625 4.95718085106383 0.183797092057456 0.669751055960293 GO:0015562 efflux transmembrane transporter activity 1/235 16/18639 0.0625 4.95718085106383 0.183797092057456 0.669751055960293 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/235 16/18639 0.0625 4.95718085106383 0.183797092057456 0.669751055960293 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/235 16/18639 0.0625 4.95718085106383 0.183797092057456 0.669751055960293 GO:0070411 I-SMAD binding 1/235 16/18639 0.0625 4.95718085106383 0.183797092057456 0.669751055960293 GO:0005507 copper ion binding 2/235 63/18639 0.0317460317460317 2.51793313069909 0.188551438129761 0.669751055960293 GO:0004549 tRNA-specific ribonuclease activity 1/235 17/18639 0.0588235294117647 4.66558197747184 0.194096597151506 0.669751055960293 GO:0008429 phosphatidylethanolamine binding 1/235 17/18639 0.0588235294117647 4.66558197747184 0.194096597151506 0.669751055960293 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/235 17/18639 0.0588235294117647 4.66558197747184 0.194096597151506 0.669751055960293 GO:0015278 intracellularly gated calcium channel activity 1/235 17/18639 0.0588235294117647 4.66558197747184 0.194096597151506 0.669751055960293 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/235 17/18639 0.0588235294117647 4.66558197747184 0.194096597151506 0.669751055960293 GO:0120013 lipid transfer activity 2/235 65/18639 0.0307692307692308 2.44045826513912 0.197696739147205 0.669751055960293 GO:0160215 deacylase activity 2/235 65/18639 0.0307692307692308 2.44045826513912 0.197696739147205 0.669751055960293 GO:0005525 GTP binding 7/235 378/18639 0.0185185185185185 1.46879432624113 0.201559161285303 0.669751055960293 GO:0000400 four-way junction DNA binding 1/235 18/18639 0.0555555555555556 4.4063829787234 0.204266680905635 0.669751055960293 GO:0003746 translation elongation factor activity 1/235 18/18639 0.0555555555555556 4.4063829787234 0.204266680905635 0.669751055960293 GO:0004706 JUN kinase kinase kinase activity 1/235 18/18639 0.0555555555555556 4.4063829787234 0.204266680905635 0.669751055960293 GO:0032393 MHC class I receptor activity 1/235 18/18639 0.0555555555555556 4.4063829787234 0.204266680905635 0.669751055960293 GO:0050811 GABA receptor binding 1/235 18/18639 0.0555555555555556 4.4063829787234 0.204266680905635 0.669751055960293 GO:0070064 proline-rich region binding 1/235 18/18639 0.0555555555555556 4.4063829787234 0.204266680905635 0.669751055960293 GO:0042277 peptide binding 5/235 249/18639 0.0200803212851406 1.59266854652653 0.206675079872386 0.669751055960293 GO:0008173 RNA methyltransferase activity 2/235 67/18639 0.0298507462686567 2.3676087646872 0.206894907994672 0.669751055960293 GO:0008234 cysteine-type peptidase activity 4/235 187/18639 0.0213903743315508 1.69657526453521 0.210944863730206 0.669751055960293 GO:0140223 general transcription initiation factor activity 2/235 68/18639 0.0294117647058824 2.33279098873592 0.211511194669915 0.669751055960293 GO:0003756 protein disulfide isomerase activity 1/235 19/18639 0.0526315789473684 4.17446808510638 0.214308962737287 0.669751055960293 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/235 19/18639 0.0526315789473684 4.17446808510638 0.214308962737287 0.669751055960293 GO:0008574 plus-end-directed microtubule motor activity 1/235 19/18639 0.0526315789473684 4.17446808510638 0.214308962737287 0.669751055960293 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/235 19/18639 0.0526315789473684 4.17446808510638 0.214308962737287 0.669751055960293 GO:0031420 alkali metal ion binding 1/235 19/18639 0.0526315789473684 4.17446808510638 0.214308962737287 0.669751055960293 GO:0042577 lipid phosphatase activity 1/235 19/18639 0.0526315789473684 4.17446808510638 0.214308962737287 0.669751055960293 GO:0046527 glucosyltransferase activity 1/235 19/18639 0.0526315789473684 4.17446808510638 0.214308962737287 0.669751055960293 GO:0097001 ceramide binding 1/235 19/18639 0.0526315789473684 4.17446808510638 0.214308962737287 0.669751055960293 GO:1990380 K48-linked deubiquitinase activity 1/235 19/18639 0.0526315789473684 4.17446808510638 0.214308962737287 0.669751055960293 GO:0004519 endonuclease activity 3/235 127/18639 0.0236220472440945 1.87358016418161 0.215927639702815 0.669751055960293 GO:0019783 ubiquitin-like protein peptidase activity 3/235 127/18639 0.0236220472440945 1.87358016418161 0.215927639702815 0.669751055960293 GO:0031490 chromatin DNA binding 3/235 128/18639 0.0234375 1.85894281914894 0.219217969038812 0.669751055960293 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/235 20/18639 0.05 3.96574468085106 0.224225041886413 0.669751055960293 GO:0015464 acetylcholine receptor activity 1/235 20/18639 0.05 3.96574468085106 0.224225041886413 0.669751055960293 GO:0016505 peptidase activator activity involved in apoptotic process 1/235 20/18639 0.05 3.96574468085106 0.224225041886413 0.669751055960293 GO:0030742 GTP-dependent protein binding 1/235 20/18639 0.05 3.96574468085106 0.224225041886413 0.669751055960293 GO:0042288 MHC class I protein binding 1/235 20/18639 0.05 3.96574468085106 0.224225041886413 0.669751055960293 GO:0052745 inositol phosphate phosphatase activity 1/235 20/18639 0.05 3.96574468085106 0.224225041886413 0.669751055960293 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3/235 130/18639 0.0230769230769231 1.83034369885434 0.225829255211311 0.669751055960293 GO:0005262 calcium channel activity 3/235 131/18639 0.0229007633587786 1.81637160955011 0.229149460437121 0.669751055960293 GO:0031072 heat shock protein binding 3/235 131/18639 0.0229007633587786 1.81637160955011 0.229149460437121 0.669751055960293 GO:0005518 collagen binding 2/235 72/18639 0.0277777777777778 2.2031914893617 0.230067792563671 0.669751055960293 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/235 21/18639 0.0476190476190476 3.77689969604863 0.234016497665815 0.669751055960293 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/235 21/18639 0.0476190476190476 3.77689969604863 0.234016497665815 0.669751055960293 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/235 21/18639 0.0476190476190476 3.77689969604863 0.234016497665815 0.669751055960293 GO:0019200 carbohydrate kinase activity 1/235 21/18639 0.0476190476190476 3.77689969604863 0.234016497665815 0.669751055960293 GO:0036122 BMP binding 1/235 21/18639 0.0476190476190476 3.77689969604863 0.234016497665815 0.669751055960293 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/235 21/18639 0.0476190476190476 3.77689969604863 0.234016497665815 0.669751055960293 GO:0051087 protein-folding chaperone binding 3/235 134/18639 0.0223880597014925 1.7757065735154 0.239163873428117 0.669751055960293 GO:0003684 damaged DNA binding 2/235 74/18639 0.027027027027027 2.14364577343301 0.23938774577652 0.669751055960293 GO:0031491 nucleosome binding 2/235 74/18639 0.027027027027027 2.14364577343301 0.23938774577652 0.669751055960293 GO:0019001 guanyl nucleotide binding 7/235 400/18639 0.0175 1.38801063829787 0.241687857716121 0.669751055960293 GO:0032561 guanyl ribonucleotide binding 7/235 400/18639 0.0175 1.38801063829787 0.241687857716121 0.669751055960293 GO:0070034 telomerase RNA binding 1/235 22/18639 0.0454545454545455 3.60522243713733 0.243684889708384 0.669751055960293 GO:0002020 protease binding 3/235 136/18639 0.0220588235294118 1.74959324155194 0.245881327942869 0.669751055960293 GO:0003887 DNA-directed DNA polymerase activity 1/235 23/18639 0.0434782608695652 3.44847363552266 0.253231758211286 0.669751055960293 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/235 23/18639 0.0434782608695652 3.44847363552266 0.253231758211286 0.669751055960293 GO:0005283 amino acid:sodium symporter activity 1/235 23/18639 0.0434782608695652 3.44847363552266 0.253231758211286 0.669751055960293 GO:0008171 O-methyltransferase activity 1/235 23/18639 0.0434782608695652 3.44847363552266 0.253231758211286 0.669751055960293 GO:0042171 lysophosphatidic acid acyltransferase activity 1/235 23/18639 0.0434782608695652 3.44847363552266 0.253231758211286 0.669751055960293 GO:0043274 phospholipase binding 1/235 23/18639 0.0434782608695652 3.44847363552266 0.253231758211286 0.669751055960293 GO:0071617 lysophospholipid acyltransferase activity 1/235 23/18639 0.0434782608695652 3.44847363552266 0.253231758211286 0.669751055960293 GO:0140103 catalytic activity, acting on a glycoprotein 1/235 23/18639 0.0434782608695652 3.44847363552266 0.253231758211286 0.669751055960293 GO:0003724 RNA helicase activity 2/235 77/18639 0.025974025974026 2.06012710693562 0.253399736017847 0.669751055960293 GO:0070851 growth factor receptor binding 3/235 139/18639 0.0215827338129496 1.71183223633859 0.256012108513502 0.669751055960293 GO:0003714 transcription corepressor activity 4/235 204/18639 0.0196078431372549 1.55519399249061 0.256800633188198 0.669751055960293 GO:0008168 methyltransferase activity 4/235 204/18639 0.0196078431372549 1.55519399249061 0.256800633188198 0.669751055960293 GO:0016791 phosphatase activity 5/235 273/18639 0.0183150183150183 1.45265372924947 0.262181048023448 0.669751055960293 GO:0005315 phosphate transmembrane transporter activity 1/235 24/18639 0.0416666666666667 3.30478723404255 0.26265862417714 0.669751055960293 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/235 24/18639 0.0416666666666667 3.30478723404255 0.26265862417714 0.669751055960293 GO:0008186 ATP-dependent activity, acting on RNA 2/235 79/18639 0.0253164556962025 2.00797199030434 0.262752735126536 0.669751055960293 GO:0000049 tRNA binding 2/235 80/18639 0.025 1.98287234042553 0.267430362058801 0.669751055960293 GO:0004518 nuclease activity 4/235 209/18639 0.0191387559808612 1.51798839458414 0.270664674853367 0.669751055960293 GO:0004709 MAP kinase kinase kinase activity 1/235 25/18639 0.04 3.17259574468085 0.271966989652207 0.669751055960293 GO:0008139 nuclear localization sequence binding 1/235 25/18639 0.04 3.17259574468085 0.271966989652207 0.669751055960293 GO:0017056 structural constituent of nuclear pore 1/235 25/18639 0.04 3.17259574468085 0.271966989652207 0.669751055960293 GO:0042974 nuclear retinoic acid receptor binding 1/235 25/18639 0.04 3.17259574468085 0.271966989652207 0.669751055960293 GO:0047617 fatty acyl-CoA hydrolase activity 1/235 25/18639 0.04 3.17259574468085 0.271966989652207 0.669751055960293 GO:0120020 cholesterol transfer activity 1/235 25/18639 0.04 3.17259574468085 0.271966989652207 0.669751055960293 GO:0001618 virus receptor activity 2/235 81/18639 0.0246913580246914 1.95839243498818 0.27210773056939 0.669751055960293 GO:0033192 calmodulin-dependent protein phosphatase activity 2/235 81/18639 0.0246913580246914 1.95839243498818 0.27210773056939 0.669751055960293 GO:0140791 histone H2AXS140 phosphatase activity 2/235 81/18639 0.0246913580246914 1.95839243498818 0.27210773056939 0.669751055960293 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/235 81/18639 0.0246913580246914 1.95839243498818 0.27210773056939 0.669751055960293 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/235 81/18639 0.0246913580246914 1.95839243498818 0.27210773056939 0.669751055960293 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/235 81/18639 0.0246913580246914 1.95839243498818 0.27210773056939 0.669751055960293 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/235 81/18639 0.0246913580246914 1.95839243498818 0.27210773056939 0.669751055960293 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/235 81/18639 0.0246913580246914 1.95839243498818 0.27210773056939 0.669751055960293 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/235 81/18639 0.0246913580246914 1.95839243498818 0.27210773056939 0.669751055960293 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/235 82/18639 0.024390243902439 1.93450960041515 0.276784106670318 0.669751055960293 GO:0033549 MAP kinase phosphatase activity 2/235 82/18639 0.024390243902439 1.93450960041515 0.276784106670318 0.669751055960293 GO:0140272 exogenous protein binding 2/235 82/18639 0.024390243902439 1.93450960041515 0.276784106670318 0.669751055960293 GO:0005112 Notch binding 1/235 26/18639 0.0384615384615385 3.0505728314239 0.281158337961637 0.669751055960293 GO:0005160 transforming growth factor beta receptor binding 1/235 26/18639 0.0384615384615385 3.0505728314239 0.281158337961637 0.669751055960293 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/235 26/18639 0.0384615384615385 3.0505728314239 0.281158337961637 0.669751055960293 GO:0008143 poly(A) binding 1/235 26/18639 0.0384615384615385 3.0505728314239 0.281158337961637 0.669751055960293 GO:0016289 acyl-CoA hydrolase activity 1/235 26/18639 0.0384615384615385 3.0505728314239 0.281158337961637 0.669751055960293 GO:0050681 nuclear androgen receptor binding 1/235 26/18639 0.0384615384615385 3.0505728314239 0.281158337961637 0.669751055960293 GO:0052742 phosphatidylinositol kinase activity 1/235 26/18639 0.0384615384615385 3.0505728314239 0.281158337961637 0.669751055960293 GO:0070412 R-SMAD binding 1/235 26/18639 0.0384615384615385 3.0505728314239 0.281158337961637 0.669751055960293 GO:0097602 cullin family protein binding 1/235 26/18639 0.0384615384615385 3.0505728314239 0.281158337961637 0.669751055960293 GO:0120014 phospholipid transfer activity 1/235 26/18639 0.0384615384615385 3.0505728314239 0.281158337961637 0.669751055960293 GO:0001540 amyloid-beta binding 2/235 83/18639 0.0240963855421687 1.91120225583184 0.281458774766826 0.669751055960293 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/235 83/18639 0.0240963855421687 1.91120225583184 0.281458774766826 0.669751055960293 GO:0008135 translation factor activity, RNA binding 2/235 83/18639 0.0240963855421687 1.91120225583184 0.281458774766826 0.669751055960293 GO:0015085 calcium ion transmembrane transporter activity 3/235 147/18639 0.0204081632653061 1.61867129830656 0.283281851030697 0.669751055960293 GO:0017018 myosin phosphatase activity 2/235 84/18639 0.0238095238095238 1.88844984802432 0.286131037313673 0.669751055960293 GO:0180051 translation factor activity 2/235 84/18639 0.0238095238095238 1.88844984802432 0.286131037313673 0.669751055960293 GO:0016741 transferase activity, transferring one-carbon groups 4/235 215/18639 0.0186046511627907 1.47562592775854 0.28746918617028 0.669751055960293 GO:0008266 poly(U) RNA binding 1/235 27/18639 0.037037037037037 2.93758865248227 0.290234133941814 0.669751055960293 GO:0023026 MHC class II protein complex binding 1/235 27/18639 0.037037037037037 2.93758865248227 0.290234133941814 0.669751055960293 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/235 86/18639 0.0232558139534884 1.84453240969817 0.295465643802416 0.669751055960293 GO:0050660 flavin adenine dinucleotide binding 2/235 86/18639 0.0232558139534884 1.84453240969817 0.295465643802416 0.669751055960293 GO:0000510 H3-H4 histone complex chaperone activity 3/235 151/18639 0.0198675496688742 1.57579258841764 0.297015565270678 0.669751055960293 GO:0140584 chromatin extrusion motor activity 3/235 151/18639 0.0198675496688742 1.57579258841764 0.297015565270678 0.669751055960293 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/235 151/18639 0.0198675496688742 1.57579258841764 0.297015565270678 0.669751055960293 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/235 151/18639 0.0198675496688742 1.57579258841764 0.297015565270678 0.669751055960293 GO:0046875 ephrin receptor binding 1/235 28/18639 0.0357142857142857 2.83267477203647 0.299195824169821 0.669751055960293 GO:0050698 proteoglycan sulfotransferase activity 1/235 28/18639 0.0357142857142857 2.83267477203647 0.299195824169821 0.669751055960293 GO:0051537 2 iron, 2 sulfur cluster binding 1/235 28/18639 0.0357142857142857 2.83267477203647 0.299195824169821 0.669751055960293 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/235 28/18639 0.0357142857142857 2.83267477203647 0.299195824169821 0.669751055960293 GO:0015616 DNA translocase activity 3/235 152/18639 0.0197368421052632 1.56542553191489 0.300455833480225 0.669751055960293 GO:0140674 ATP-dependent histone chaperone activity 3/235 152/18639 0.0197368421052632 1.56542553191489 0.300455833480225 0.669751055960293 GO:0003774 cytoskeletal motor activity 3/235 153/18639 0.0196078431372549 1.55519399249061 0.303898223129572 0.669751055960293 GO:0061775 cohesin loader activity 3/235 153/18639 0.0196078431372549 1.55519399249061 0.303898223129572 0.669751055960293 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/235 29/18639 0.0344827586206897 2.73499633162142 0.308044837190082 0.669751055960293 GO:0005416 amino acid:monoatomic cation symporter activity 1/235 29/18639 0.0344827586206897 2.73499633162142 0.308044837190082 0.669751055960293 GO:0051861 glycolipid binding 1/235 29/18639 0.0344827586206897 2.73499633162142 0.308044837190082 0.669751055960293 GO:0097472 cyclin-dependent protein kinase activity 1/235 29/18639 0.0344827586206897 2.73499633162142 0.308044837190082 0.669751055960293 GO:0099604 ligand-gated calcium channel activity 1/235 29/18639 0.0344827586206897 2.73499633162142 0.308044837190082 0.669751055960293 GO:0106222 lncRNA binding 1/235 29/18639 0.0344827586206897 2.73499633162142 0.308044837190082 0.669751055960293 GO:0003727 single-stranded RNA binding 2/235 89/18639 0.0224719101123595 1.78235715993306 0.309433074060788 0.669751055960293 GO:0004386 helicase activity 3/235 155/18639 0.0193548387096774 1.53512697323267 0.310788165358076 0.669751055960293 GO:0140375 immune receptor activity 3/235 156/18639 0.0192307692307692 1.52528641571195 0.314235125865551 0.669751055960293 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/235 30/18639 0.0333333333333333 2.64382978723404 0.316782583738193 0.669751055960293 GO:0008187 poly-pyrimidine tract binding 1/235 30/18639 0.0333333333333333 2.64382978723404 0.316782583738193 0.669751055960293 GO:0033612 receptor serine/threonine kinase binding 1/235 30/18639 0.0333333333333333 2.64382978723404 0.316782583738193 0.669751055960293 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/235 30/18639 0.0333333333333333 2.64382978723404 0.316782583738193 0.669751055960293 GO:0070566 adenylyltransferase activity 1/235 30/18639 0.0333333333333333 2.64382978723404 0.316782583738193 0.669751055960293 GO:0061134 peptidase regulator activity 4/235 226/18639 0.0176991150442478 1.40380342684993 0.318627295552964 0.669751055960293 GO:0140658 ATP-dependent chromatin remodeler activity 3/235 158/18639 0.0189873417721519 1.50597899272825 0.321131571435444 0.669751055960293 GO:0052689 carboxylic ester hydrolase activity 2/235 92/18639 0.0217391304347826 1.72423681776133 0.32334452619427 0.669751055960293 GO:0005452 solute:inorganic anion antiporter activity 1/235 31/18639 0.032258064516129 2.55854495538778 0.325410456961984 0.669751055960293 GO:0008327 methyl-CpG binding 1/235 31/18639 0.032258064516129 2.55854495538778 0.325410456961984 0.669751055960293 GO:0016411 acylglycerol O-acyltransferase activity 1/235 31/18639 0.032258064516129 2.55854495538778 0.325410456961984 0.669751055960293 GO:0017147 Wnt-protein binding 1/235 31/18639 0.032258064516129 2.55854495538778 0.325410456961984 0.669751055960293 GO:0051219 phosphoprotein binding 2/235 93/18639 0.021505376344086 1.70569663692519 0.327966564456044 0.669751055960293 GO:0003689 DNA clamp loader activity 3/235 160/18639 0.01875 1.48715425531915 0.328029484569447 0.669751055960293 GO:0004866 endopeptidase inhibitor activity 3/235 161/18639 0.0186335403726708 1.47791727236686 0.331478292561046 0.669751055960293 GO:0005178 integrin binding 3/235 161/18639 0.0186335403726708 1.47791727236686 0.331478292561046 0.669751055960293 GO:0031369 translation initiation factor binding 1/235 32/18639 0.03125 2.47859042553192 0.333929832639861 0.669751055960293 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/235 32/18639 0.03125 2.47859042553192 0.333929832639861 0.669751055960293 GO:0042910 xenobiotic transmembrane transporter activity 1/235 32/18639 0.03125 2.47859042553192 0.333929832639861 0.669751055960293 GO:0070717 poly-purine tract binding 1/235 32/18639 0.03125 2.47859042553192 0.333929832639861 0.669751055960293 GO:0120015 sterol transfer activity 1/235 32/18639 0.03125 2.47859042553192 0.333929832639861 0.669751055960293 GO:0140142 nucleocytoplasmic carrier activity 1/235 32/18639 0.03125 2.47859042553192 0.333929832639861 0.669751055960293 GO:0004867 serine-type endopeptidase inhibitor activity 2/235 95/18639 0.0210526315789474 1.66978723404255 0.337184741029134 0.669751055960293 GO:0008276 protein methyltransferase activity 2/235 95/18639 0.0210526315789474 1.66978723404255 0.337184741029134 0.669751055960293 GO:0140713 histone chaperone activity 3/235 164/18639 0.0182926829268293 1.45088220031136 0.341820850907661 0.669751055960293 GO:0019239 deaminase activity 1/235 33/18639 0.0303030303030303 2.40348162475822 0.342342069396438 0.669751055960293 GO:0030296 protein tyrosine kinase activator activity 1/235 33/18639 0.0303030303030303 2.40348162475822 0.342342069396438 0.669751055960293 GO:0140416 transcription regulator inhibitor activity 1/235 33/18639 0.0303030303030303 2.40348162475822 0.342342069396438 0.669751055960293 GO:0008175 tRNA methyltransferase activity 1/235 34/18639 0.0294117647058824 2.33279098873592 0.350648508915509 0.669751055960293 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/235 34/18639 0.0294117647058824 2.33279098873592 0.350648508915509 0.669751055960293 GO:0016831 carboxy-lyase activity 1/235 34/18639 0.0294117647058824 2.33279098873592 0.350648508915509 0.669751055960293 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/235 34/18639 0.0294117647058824 2.33279098873592 0.350648508915509 0.669751055960293 GO:0030332 cyclin binding 1/235 34/18639 0.0294117647058824 2.33279098873592 0.350648508915509 0.669751055960293 GO:0090482 vitamin transmembrane transporter activity 1/235 34/18639 0.0294117647058824 2.33279098873592 0.350648508915509 0.669751055960293 GO:0008170 N-methyltransferase activity 2/235 98/18639 0.0204081632653061 1.61867129830656 0.350939667698752 0.669751055960293 GO:0042626 ATPase-coupled transmembrane transporter activity 2/235 98/18639 0.0204081632653061 1.61867129830656 0.350939667698752 0.669751055960293 GO:0005154 epidermal growth factor receptor binding 1/235 35/18639 0.0285714285714286 2.26613981762918 0.358850476150384 0.671014277299387 GO:0005343 organic acid:sodium symporter activity 1/235 35/18639 0.0285714285714286 2.26613981762918 0.358850476150384 0.671014277299387 GO:0016229 steroid dehydrogenase activity 1/235 35/18639 0.0285714285714286 2.26613981762918 0.358850476150384 0.671014277299387 GO:0034061 DNA polymerase activity 1/235 35/18639 0.0285714285714286 2.26613981762918 0.358850476150384 0.671014277299387 GO:0140566 histone reader activity 1/235 35/18639 0.0285714285714286 2.26613981762918 0.358850476150384 0.671014277299387 GO:0030414 peptidase inhibitor activity 3/235 169/18639 0.0177514792899408 1.40795669142641 0.359029779366831 0.671014277299387 GO:0140098 catalytic activity, acting on RNA 6/235 387/18639 0.0155038759689922 1.22968827313211 0.362476929859291 0.67419155764794 GO:0000993 RNA polymerase II complex binding 1/235 36/18639 0.0277777777777778 2.2031914893617 0.366949279531628 0.67419155764794 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/235 36/18639 0.0277777777777778 2.2031914893617 0.366949279531628 0.67419155764794 GO:0005484 SNAP receptor activity 1/235 36/18639 0.0277777777777778 2.2031914893617 0.366949279531628 0.67419155764794 GO:0055106 ubiquitin-protein transferase regulator activity 1/235 36/18639 0.0277777777777778 2.2031914893617 0.366949279531628 0.67419155764794 GO:0004722 protein serine/threonine phosphatase activity 2/235 103/18639 0.0194174757281553 1.54009502168973 0.373640438167321 0.681949149179017 GO:0019213 deacetylase activity 1/235 37/18639 0.027027027027027 2.14364577343301 0.374946211172227 0.681949149179017 GO:0023023 MHC protein complex binding 1/235 37/18639 0.027027027027027 2.14364577343301 0.374946211172227 0.681949149179017 GO:0033218 amide binding 4/235 247/18639 0.0161943319838057 1.28445171849427 0.378637981540065 0.686360488276639 GO:0042887 amide transmembrane transporter activity 1/235 38/18639 0.0263157894736842 2.08723404255319 0.382842547070224 0.691668868373537 GO:0140104 molecular carrier activity 4/235 249/18639 0.0160642570281124 1.27413483722123 0.384347678489825 0.692081201798954 GO:0043021 ribonucleoprotein complex binding 3/235 177/18639 0.0169491525423729 1.34432023079697 0.386420646766771 0.69245008031498 GO:0008013 beta-catenin binding 2/235 106/18639 0.0188679245283019 1.49650742673625 0.387107701725902 0.69245008031498 GO:0005319 lipid transporter activity 3/235 178/18639 0.0168539325842697 1.3367678699498 0.389827184529331 0.69502083557532 GO:0004177 aminopeptidase activity 1/235 40/18639 0.025 1.98287234042553 0.398338456254131 0.705553736240978 GO:0032451 demethylase activity 1/235 40/18639 0.025 1.98287234042553 0.398338456254131 0.705553736240978 GO:0004175 endopeptidase activity 6/235 405/18639 0.0148148148148148 1.17503546099291 0.402963926342364 0.706748718667368 GO:0004222 metalloendopeptidase activity 2/235 110/18639 0.0181818181818182 1.44208897485493 0.404864033659324 0.706748718667368 GO:0001727 lipid kinase activity 1/235 41/18639 0.024390243902439 1.93450960041515 0.405940502750194 0.706748718667368 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/235 41/18639 0.024390243902439 1.93450960041515 0.405940502750194 0.706748718667368 GO:0042287 MHC protein binding 1/235 41/18639 0.024390243902439 1.93450960041515 0.405940502750194 0.706748718667368 GO:0061135 endopeptidase regulator activity 3/235 184/18639 0.016304347826087 1.293177613321 0.410162808999542 0.706748718667368 GO:0004520 DNA endonuclease activity 1/235 42/18639 0.0238095238095238 1.88844984802432 0.413446900311959 0.706748718667368 GO:0031492 nucleosomal DNA binding 1/235 42/18639 0.0238095238095238 1.88844984802432 0.413446900311959 0.706748718667368 GO:0035198 miRNA binding 1/235 42/18639 0.0238095238095238 1.88844984802432 0.413446900311959 0.706748718667368 GO:0043175 RNA polymerase core enzyme binding 1/235 42/18639 0.0238095238095238 1.88844984802432 0.413446900311959 0.706748718667368 GO:1901981 phosphatidylinositol phosphate binding 3/235 185/18639 0.0162162162162162 1.2861874640598 0.413532912630818 0.706748718667368 GO:0005245 voltage-gated calcium channel activity 1/235 43/18639 0.0232558139534884 1.84453240969817 0.420858847315599 0.706748718667368 GO:0008375 acetylglucosaminyltransferase activity 1/235 43/18639 0.0232558139534884 1.84453240969817 0.420858847315599 0.706748718667368 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/235 43/18639 0.0232558139534884 1.84453240969817 0.420858847315599 0.706748718667368 GO:0140597 protein carrier chaperone 3/235 188/18639 0.0159574468085106 1.2656631960163 0.423606473502412 0.706748718667368 GO:0017124 SH3 domain binding 2/235 115/18639 0.0173913043478261 1.37938945420907 0.426708075235606 0.706748718667368 GO:0004857 enzyme inhibitor activity 6/235 416/18639 0.0144230769230769 1.14396481178396 0.427656134917893 0.706748718667368 GO:0001046 core promoter sequence-specific DNA binding 1/235 44/18639 0.0227272727272727 1.80261121856867 0.428177527186584 0.706748718667368 GO:0001223 transcription coactivator binding 1/235 44/18639 0.0227272727272727 1.80261121856867 0.428177527186584 0.706748718667368 GO:0016790 thiolester hydrolase activity 1/235 44/18639 0.0227272727272727 1.80261121856867 0.428177527186584 0.706748718667368 GO:0019205 nucleobase-containing compound kinase activity 1/235 44/18639 0.0227272727272727 1.80261121856867 0.428177527186584 0.706748718667368 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/235 44/18639 0.0227272727272727 1.80261121856867 0.428177527186584 0.706748718667368 GO:0016887 ATP hydrolysis activity 6/235 417/18639 0.0143884892086331 1.14122149089239 0.429894786609239 0.706748718667368 GO:0005261 monoatomic cation channel activity 5/235 341/18639 0.0146627565982405 1.16297497972172 0.430308260443231 0.706748718667368 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/235 45/18639 0.0222222222222222 1.76255319148936 0.435404108585409 0.710810321847264 GO:0042605 peptide antigen binding 1/235 45/18639 0.0222222222222222 1.76255319148936 0.435404108585409 0.710810321847264 GO:0005543 phospholipid binding 7/235 497/18639 0.0140845070422535 1.11711117770453 0.437180636931123 0.711567282932939 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/235 46/18639 0.0217391304347826 1.72423681776133 0.442539745591025 0.718133359611783 GO:0001784 phosphotyrosine residue binding 1/235 47/18639 0.0212765957446809 1.68755092802173 0.449585577882001 0.723072353744939 GO:0005504 fatty acid binding 1/235 47/18639 0.0212765957446809 1.68755092802173 0.449585577882001 0.723072353744939 GO:0140938 histone H3 methyltransferase activity 1/235 47/18639 0.0212765957446809 1.68755092802173 0.449585577882001 0.723072353744939 GO:0003697 single-stranded DNA binding 2/235 121/18639 0.0165289256198347 1.31098997714085 0.452358341272619 0.725379351981536 GO:0032266 phosphatidylinositol-3-phosphate binding 1/235 48/18639 0.0208333333333333 1.65239361702128 0.456542730915442 0.72782667715172 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/235 122/18639 0.0163934426229508 1.30024415765609 0.456570240279677 0.72782667715172 GO:0061630 ubiquitin protein ligase activity 5/235 353/18639 0.0141643059490085 1.12344041950455 0.459845171139287 0.729669514473262 GO:0008017 microtubule binding 4/235 276/18639 0.0144927536231884 1.14949121184089 0.460418771125195 0.729669514473262 GO:0001222 transcription corepressor binding 1/235 49/18639 0.0204081632653061 1.61867129830656 0.463412316103698 0.730143823628501 GO:0035254 glutamate receptor binding 1/235 49/18639 0.0204081632653061 1.61867129830656 0.463412316103698 0.730143823628501 GO:0004674 protein serine/threonine kinase activity 6/235 433/18639 0.0138568129330254 1.09905164365387 0.465491825820519 0.73129440462238 GO:0015605 organophosphate ester transmembrane transporter activity 1/235 50/18639 0.02 1.58629787234043 0.470195430988885 0.736548912127098 GO:0003743 translation initiation factor activity 1/235 51/18639 0.0196078431372549 1.55519399249061 0.476893159415245 0.738533897974817 GO:0005048 signal sequence binding 1/235 51/18639 0.0196078431372549 1.55519399249061 0.476893159415245 0.738533897974817 GO:0016830 carbon-carbon lyase activity 1/235 51/18639 0.0196078431372549 1.55519399249061 0.476893159415245 0.738533897974817 GO:0106310 protein serine kinase activity 5/235 361/18639 0.0138504155124654 1.09854423292273 0.479298493275809 0.738533897974817 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/235 128/18639 0.015625 1.23929521276596 0.481443700743501 0.738533897974817 GO:0035091 phosphatidylinositol binding 4/235 284/18639 0.0140845070422535 1.11711117770453 0.482389442678946 0.738533897974817 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/235 52/18639 0.0192307692307692 1.52528641571195 0.483506571699376 0.738533897974817 GO:0030159 signaling receptor complex adaptor activity 1/235 52/18639 0.0192307692307692 1.52528641571195 0.483506571699376 0.738533897974817 GO:0042578 phosphoric ester hydrolase activity 5/235 363/18639 0.0137741046831956 1.09249164761737 0.484126502817141 0.738533897974817 GO:0005516 calmodulin binding 3/235 207/18639 0.0144927536231884 1.14949121184089 0.485850343287574 0.738533897974817 GO:0008146 sulfotransferase activity 1/235 53/18639 0.0188679245283019 1.49650742673625 0.490036724798351 0.738533897974817 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/235 53/18639 0.0188679245283019 1.49650742673625 0.490036724798351 0.738533897974817 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/235 53/18639 0.0188679245283019 1.49650742673625 0.490036724798351 0.738533897974817 GO:0019207 kinase regulator activity 4/235 287/18639 0.0139372822299652 1.10543405738009 0.490539120426078 0.738533897974817 GO:0008094 ATP-dependent activity, acting on DNA 3/235 210/18639 0.0142857142857143 1.13306990881459 0.49539089824367 0.743023945658038 GO:0015485 cholesterol binding 1/235 54/18639 0.0185185185185185 1.46879432624113 0.496484662475763 0.743023945658038 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/235 132/18639 0.0151515151515152 1.20174081237911 0.497634118586472 0.743023945658038 GO:0004842 ubiquitin-protein transferase activity 6/235 449/18639 0.0133630289532294 1.05988721982656 0.500501296678209 0.744582024823187 GO:0046873 metal ion transmembrane transporter activity 6/235 450/18639 0.0133333333333333 1.05753191489362 0.502664576154022 0.744582024823187 GO:0008374 O-acyltransferase activity 1/235 55/18639 0.0181818181818182 1.44208897485493 0.502851415465712 0.744582024823187 GO:0061659 ubiquitin-like protein ligase activity 5/235 372/18639 0.0134408602150538 1.06606039807824 0.505655704943956 0.744582024823187 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/235 56/18639 0.0178571428571429 1.41633738601824 0.509138001634758 0.744582024823187 GO:0170055 lipid transmembrane transporter activity 1/235 56/18639 0.0178571428571429 1.41633738601824 0.509138001634758 0.744582024823187 GO:0015297 antiporter activity 2/235 135/18639 0.0148148148148148 1.17503546099291 0.509564335254857 0.744582024823187 GO:0016779 nucleotidyltransferase activity 2/235 136/18639 0.0147058823529412 1.16639549436796 0.51349990252817 0.744582024823187 GO:0099094 ligand-gated monoatomic cation channel activity 2/235 136/18639 0.0147058823529412 1.16639549436796 0.51349990252817 0.744582024823187 GO:0140789 histone phosphatase activity 2/235 136/18639 0.0147058823529412 1.16639549436796 0.51349990252817 0.744582024823187 GO:0016504 peptidase activator activity 1/235 57/18639 0.0175438596491228 1.39148936170213 0.515345426141879 0.744582024823187 GO:0016922 nuclear receptor binding 2/235 137/18639 0.0145985401459854 1.15788165864265 0.517414696211415 0.744582024823187 GO:0017116 single-stranded DNA helicase activity 1/235 58/18639 0.0172413793103448 1.36749816581071 0.521474681596441 0.744582024823187 GO:0030295 protein kinase activator activity 2/235 139/18639 0.0143884892086331 1.14122149089239 0.525181554400797 0.744582024823187 GO:0140101 catalytic activity, acting on a tRNA 2/235 139/18639 0.0143884892086331 1.14122149089239 0.525181554400797 0.744582024823187 GO:0001786 phosphatidylserine binding 1/235 59/18639 0.0169491525423729 1.34432023079697 0.527526748214213 0.744582024823187 GO:0004879 nuclear receptor activity 1/235 59/18639 0.0169491525423729 1.34432023079697 0.527526748214213 0.744582024823187 GO:0031593 polyubiquitin modification-dependent protein binding 1/235 59/18639 0.0169491525423729 1.34432023079697 0.527526748214213 0.744582024823187 GO:0036002 pre-mRNA binding 1/235 59/18639 0.0169491525423729 1.34432023079697 0.527526748214213 0.744582024823187 GO:0045309 protein phosphorylated amino acid binding 1/235 59/18639 0.0169491525423729 1.34432023079697 0.527526748214213 0.744582024823187 GO:0070063 RNA polymerase binding 1/235 59/18639 0.0169491525423729 1.34432023079697 0.527526748214213 0.744582024823187 GO:0001098 basal transcription machinery binding 1/235 60/18639 0.0166666666666667 1.32191489361702 0.533502593971461 0.745253623537454 GO:0001099 basal RNA polymerase II transcription machinery binding 1/235 60/18639 0.0166666666666667 1.32191489361702 0.533502593971461 0.745253623537454 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/235 60/18639 0.0166666666666667 1.32191489361702 0.533502593971461 0.745253623537454 GO:0098531 ligand-modulated transcription factor activity 1/235 60/18639 0.0166666666666667 1.32191489361702 0.533502593971461 0.745253623537454 GO:0015631 tubulin binding 5/235 385/18639 0.012987012987013 1.03006355346781 0.536111439235883 0.746972750811951 GO:0019955 cytokine binding 2/235 144/18639 0.0138888888888889 1.10159574468085 0.544228615864705 0.755791185451432 GO:0015179 L-amino acid transmembrane transporter activity 1/235 62/18639 0.0161290322580645 1.27927247769389 0.545229434523081 0.755791185451432 GO:0022824 transmitter-gated monoatomic ion channel activity 1/235 63/18639 0.0158730158730159 1.25896656534954 0.550982305432651 0.757950278031718 GO:0022835 transmitter-gated channel activity 1/235 63/18639 0.0158730158730159 1.25896656534954 0.550982305432651 0.757950278031718 GO:1901682 sulfur compound transmembrane transporter activity 1/235 63/18639 0.0158730158730159 1.25896656534954 0.550982305432651 0.757950278031718 GO:0004536 DNA nuclease activity 1/235 64/18639 0.015625 1.23929521276596 0.556662708007119 0.763825791746478 GO:0019209 kinase activator activity 2/235 148/18639 0.0135135135135135 1.0718228867165 0.559080787105393 0.76520653184627 GO:0019843 rRNA binding 1/235 65/18639 0.0153846153846154 1.22022913256956 0.562271551270556 0.765706484393571 GO:0038024 cargo receptor activity 1/235 65/18639 0.0153846153846154 1.22022913256956 0.562271551270556 0.765706484393571 GO:0019787 ubiquitin-like protein transferase activity 6/235 479/18639 0.0125260960334029 0.993505974325945 0.563800966722214 0.765864972339449 GO:0022836 gated channel activity 4/235 318/18639 0.0125786163522013 0.997671617824167 0.571283695101339 0.77292724258012 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/235 67/18639 0.0149253731343284 1.1838043823436 0.573278139330642 0.77292724258012 GO:0042054 histone methyltransferase activity 1/235 67/18639 0.0149253731343284 1.1838043823436 0.573278139330642 0.77292724258012 GO:0003777 microtubule motor activity 1/235 68/18639 0.0147058823529412 1.16639549436796 0.578677645967369 0.774427862010653 GO:0005548 phospholipid transporter activity 1/235 68/18639 0.0147058823529412 1.16639549436796 0.578677645967369 0.774427862010653 GO:0032934 sterol binding 1/235 68/18639 0.0147058823529412 1.16639549436796 0.578677645967369 0.774427862010653 GO:0016279 protein-lysine N-methyltransferase activity 1/235 69/18639 0.0144927536231884 1.14949121184089 0.584009117250428 0.775877235169943 GO:0098960 postsynaptic neurotransmitter receptor activity 1/235 69/18639 0.0144927536231884 1.14949121184089 0.584009117250428 0.775877235169943 GO:0030695 GTPase regulator activity 6/235 489/18639 0.0122699386503067 0.973188878736457 0.584055188098407 0.775877235169943 GO:0060589 nucleoside-triphosphatase regulator activity 6/235 490/18639 0.0122448979591837 0.971202778983934 0.58605451631852 0.776629701331633 GO:0016278 lysine N-methyltransferase activity 1/235 70/18639 0.0142857142857143 1.13306990881459 0.589273406827495 0.777095344283461 GO:0016782 transferase activity, transferring sulphur-containing groups 1/235 70/18639 0.0142857142857143 1.13306990881459 0.589273406827495 0.777095344283461 GO:0016755 aminoacyltransferase activity 6/235 496/18639 0.0120967741935484 0.959454358270419 0.59794702089286 0.786619624572646 GO:0003924 GTPase activity 4/235 331/18639 0.0120845921450151 0.958488140386964 0.602965243824368 0.787817276288611 GO:0004521 RNA endonuclease activity 1/235 73/18639 0.0136986301369863 1.08650539201399 0.604671562612661 0.787817276288611 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/235 73/18639 0.0136986301369863 1.08650539201399 0.604671562612661 0.787817276288611 GO:0043539 protein serine/threonine kinase activator activity 1/235 73/18639 0.0136986301369863 1.08650539201399 0.604671562612661 0.787817276288611 GO:0003678 DNA helicase activity 1/235 74/18639 0.0135135135135135 1.0718228867165 0.609675450514526 0.790536110475773 GO:0048029 monosaccharide binding 1/235 74/18639 0.0135135135135135 1.0718228867165 0.609675450514526 0.790536110475773 GO:0140097 catalytic activity, acting on DNA 4/235 336/18639 0.0119047619047619 0.944224924012158 0.614770149551031 0.79523966839298 GO:0015103 inorganic anion transmembrane transporter activity 2/235 165/18639 0.0121212121212121 0.961392649903288 0.618318135316256 0.797544381391246 GO:0051536 iron-sulfur cluster binding 1/235 76/18639 0.0131578947368421 1.0436170212766 0.619494805471798 0.797544381391246 GO:0015399 primary active transmembrane transporter activity 2/235 166/18639 0.0120481927710843 0.955601127915919 0.62160603926079 0.798366050424996 GO:0051540 metal cluster binding 1/235 77/18639 0.012987012987013 1.03006355346781 0.62431184585935 0.79994567483633 GO:0019887 protein kinase regulator activity 3/235 255/18639 0.0117647058823529 0.933116395494368 0.626554072439926 0.800925252977453 GO:0005201 extracellular matrix structural constituent 2/235 168/18639 0.0119047619047619 0.944224924012158 0.628116486682104 0.801033260662825 GO:0015370 solute:sodium symporter activity 1/235 79/18639 0.0126582278481013 1.00398599515217 0.63376451231815 0.802570947842143 GO:0016835 carbon-oxygen lyase activity 1/235 79/18639 0.0126582278481013 1.00398599515217 0.63376451231815 0.802570947842143 GO:0033293 monocarboxylic acid binding 1/235 79/18639 0.0126582278481013 1.00398599515217 0.63376451231815 0.802570947842143 GO:0048306 calcium-dependent protein binding 1/235 80/18639 0.0125 0.991436170212766 0.638401653460674 0.806558732344255 GO:0015101 organic cation transmembrane transporter activity 1/235 81/18639 0.0123456790123457 0.97919621749409 0.642980327496815 0.808903685753517 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 4/235 349/18639 0.0114613180515759 0.909053221971591 0.644432604250233 0.808903685753517 GO:0003730 mRNA 3'-UTR binding 3/235 262/18639 0.0114503816793893 0.908185804775053 0.644735041043394 0.808903685753517 GO:0004721 phosphoprotein phosphatase activity 2/235 175/18639 0.0114285714285714 0.906455927051672 0.650219916703197 0.812025794592472 GO:0022832 voltage-gated channel activity 2/235 175/18639 0.0114285714285714 0.906455927051672 0.650219916703197 0.812025794592472 GO:0004527 exonuclease activity 1/235 84/18639 0.0119047619047619 0.944224924012158 0.65637284187551 0.815949725450749 GO:0051117 ATPase binding 1/235 84/18639 0.0119047619047619 0.944224924012158 0.65637284187551 0.815949725450749 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 3/235 268/18639 0.0111940298507463 0.887853286757701 0.659817189612836 0.818354500618209 GO:0008514 organic anion transmembrane transporter activity 3/235 269/18639 0.0111524163568773 0.884552716918453 0.662285710985083 0.819540765648208 GO:0005096 GTPase activator activity 3/235 271/18639 0.011070110701107 0.878024652586951 0.667183996686149 0.823721471990644 GO:0005216 monoatomic ion channel activity 5/235 448/18639 0.0111607142857143 0.885210866261398 0.669683283966683 0.824928045249868 GO:0005126 cytokine receptor binding 3/235 275/18639 0.0109090909090909 0.865253384912959 0.676825530789343 0.827018181507235 GO:0008237 metallopeptidase activity 2/235 184/18639 0.0108695652173913 0.862118408880666 0.67709526614635 0.827018181507235 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/235 89/18639 0.0112359550561798 0.891178579966531 0.677591093382718 0.827018181507235 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/235 89/18639 0.0112359550561798 0.891178579966531 0.677591093382718 0.827018181507235 GO:0140793 histone H2AXY142 phosphatase activity 1/235 90/18639 0.0111111111111111 0.881276595744681 0.681675518884338 0.827018181507235 GO:0015276 ligand-gated monoatomic ion channel activity 2/235 186/18639 0.010752688172043 0.852848318462594 0.6828352802474 0.827018181507235 GO:0001217 DNA-binding transcription repressor activity 3/235 278/18639 0.0107913669064748 0.855916118169294 0.683921107838613 0.827018181507235 GO:0072341 modified amino acid binding 1/235 91/18639 0.010989010989011 0.871592237549685 0.685708418397098 0.827018181507235 GO:0022804 active transmembrane transporter activity 5/235 457/18639 0.0109409190371991 0.867777829507891 0.686570640488225 0.827018181507235 GO:0022834 ligand-gated channel activity 2/235 188/18639 0.0106382978723404 0.843775464010865 0.688491916962105 0.827018181507235 GO:0046943 carboxylic acid transmembrane transporter activity 2/235 188/18639 0.0106382978723404 0.843775464010865 0.688491916962105 0.827018181507235 GO:0043178 alcohol binding 1/235 92/18639 0.0108695652173913 0.862118408880666 0.689690439190536 0.827018181507235 GO:0005342 organic acid transmembrane transporter activity 2/235 189/18639 0.0105820105820106 0.839311043566363 0.691289141122497 0.827105329996454 GO:0031267 small GTPase binding 3/235 283/18639 0.0106007067137809 0.840793925268777 0.695489367200285 0.830297878904305 GO:0042562 hormone binding 1/235 94/18639 0.0106382978723404 0.843775464010865 0.697504393315745 0.83087336522447 GO:0015291 secondary active transmembrane transporter activity 3/235 287/18639 0.0104529616724739 0.829075543035066 0.70451283106131 0.836272079685442 GO:0004896 cytokine receptor activity 1/235 96/18639 0.0104166666666667 0.826196808510638 0.705122399291969 0.836272079685442 GO:0030594 neurotransmitter receptor activity 1/235 97/18639 0.0103092783505155 0.817679315639395 0.70885945565644 0.838868613462424 GO:0004725 protein tyrosine phosphatase activity 1/235 98/18639 0.0102040816326531 0.809335649153278 0.712549350377653 0.840018010313345 GO:0016758 hexosyltransferase activity 2/235 197/18639 0.0101522842639594 0.805227346365698 0.712930414657083 0.840018010313345 GO:0016829 lyase activity 2/235 200/18639 0.01 0.793148936170213 0.720713502004091 0.847346460056871 GO:0008238 exopeptidase activity 1/235 102/18639 0.00980392156862745 0.777596996245307 0.726849055503979 0.850868656767076 GO:0015171 amino acid transmembrane transporter activity 1/235 102/18639 0.00980392156862745 0.777596996245307 0.726849055503979 0.850868656767076 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 5/235 484/18639 0.0103305785123967 0.81936873571303 0.733688998702726 0.857024649346719 GO:0031625 ubiquitin protein ligase binding 3/235 302/18639 0.00993377483443709 0.787896294208821 0.736540818654452 0.85850564238863 GO:0000149 SNARE binding 1/235 106/18639 0.00943396226415094 0.748253713368125 0.740440274801136 0.859354665829156 GO:0004497 monooxygenase activity 1/235 106/18639 0.00943396226415094 0.748253713368125 0.740440274801136 0.859354665829156 GO:0051015 actin filament binding 2/235 209/18639 0.00956937799043062 0.75899419729207 0.743005367846293 0.860489122591219 GO:0001216 DNA-binding transcription activator activity 5/235 491/18639 0.010183299389002 0.807687307708974 0.745032791031001 0.860997383238385 GO:0005496 steroid binding 1/235 108/18639 0.00925925925925926 0.734397163120567 0.746981195284668 0.861412357115511 GO:0005200 structural constituent of cytoskeleton 1/235 112/18639 0.00892857142857143 0.708168693009119 0.759574695051969 0.871278773990655 GO:0043022 ribosome binding 1/235 112/18639 0.00892857142857143 0.708168693009119 0.759574695051969 0.871278773990655 GO:0051020 GTPase binding 3/235 315/18639 0.00952380952380952 0.755379939209727 0.762035428017012 0.871278773990655 GO:0035401 histone H3Y41 kinase activity 1/235 115/18639 0.00869565217391304 0.689694727104533 0.768608423172443 0.871278773990655 GO:0140801 histone H2AXY142 kinase activity 1/235 115/18639 0.00869565217391304 0.689694727104533 0.768608423172443 0.871278773990655 GO:0015294 solute:monoatomic cation symporter activity 1/235 116/18639 0.00862068965517241 0.683749082905356 0.771543913377284 0.871278773990655 GO:0044389 ubiquitin-like protein ligase binding 3/235 322/18639 0.0093167701863354 0.738958636183428 0.774918945534451 0.871278773990655 GO:0004540 RNA nuclease activity 1/235 121/18639 0.00826446280991736 0.655494988570424 0.785674349019212 0.871278773990655 GO:0051082 unfolded protein binding 1/235 121/18639 0.00826446280991736 0.655494988570424 0.785674349019212 0.871278773990655 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/235 229/18639 0.00873362445414847 0.692706494471802 0.787151567459028 0.871278773990655 GO:0008528 G protein-coupled peptide receptor activity 1/235 122/18639 0.00819672131147541 0.650122078828043 0.788394217686481 0.871278773990655 GO:0005085 guanyl-nucleotide exchange factor activity 2/235 230/18639 0.00869565217391304 0.689694727104533 0.789173923718573 0.871278773990655 GO:0005125 cytokine activity 2/235 234/18639 0.00854700854700855 0.677905073649755 0.797095596112716 0.871278773990655 GO:0042826 histone deacetylase binding 1/235 127/18639 0.0078740157480315 0.624526721393868 0.801486564265023 0.871278773990655 GO:0001653 peptide receptor activity 1/235 128/18639 0.0078125 0.619647606382979 0.804006586812436 0.871278773990655 GO:0035591 signaling adaptor activity 1/235 129/18639 0.00775193798449612 0.614844136566056 0.80649475342143 0.871278773990655 GO:0005539 glycosaminoglycan binding 2/235 242/18639 0.00826446280991736 0.655494988570424 0.812154976800258 0.871278773990655 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 2/235 243/18639 0.00823045267489712 0.652797478329393 0.813965897611258 0.871278773990655 GO:0004676 3-phosphoinositide-dependent protein kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:0004711 ribosomal protein S6 kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:0035175 histone H3S10 kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:0035979 histone H2AXS139 kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:0044022 histone H3S28 kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:0044023 histone H4S1 kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:0044024 histone H2AS1 kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:0044025 histone H2BS14 kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:0072354 histone H3T3 kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:0072371 histone H2AS121 kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:0072518 Rho-dependent protein serine/threonine kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:0140823 histone H2BS36 kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:0140855 histone H3S57 kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:0140995 histone H2A kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:0140997 histone H4 kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:0140998 histone H2B kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:1990244 histone H2AT120 kinase activity 2/235 245/18639 0.00816326530612245 0.647468519322623 0.817541196171176 0.871278773990655 GO:0004677 DNA-dependent protein kinase activity 2/235 246/18639 0.00813008130081301 0.644836533471718 0.819305778052204 0.871278773990655 GO:0140857 histone H3T45 kinase activity 2/235 246/18639 0.00813008130081301 0.644836533471718 0.819305778052204 0.871278773990655 GO:0035402 histone H3T11 kinase activity 2/235 247/18639 0.00809716599190283 0.642225859247136 0.821055117588435 0.871278773990655 GO:0035403 histone H3T6 kinase activity 2/235 247/18639 0.00809716599190283 0.642225859247136 0.821055117588435 0.871278773990655 GO:0042393 histone binding 2/235 247/18639 0.00809716599190283 0.642225859247136 0.821055117588435 0.871278773990655 GO:0004679 AMP-activated protein kinase activity 2/235 248/18639 0.00806451612903226 0.639636238846946 0.822789316575112 0.871278773990655 GO:0044325 transmembrane transporter binding 1/235 136/18639 0.00735294117647059 0.58319774718398 0.823053011592648 0.871278773990655 GO:0141003 histone H2AX kinase activity 3/235 354/18639 0.00847457627118644 0.672160115398485 0.826724458443275 0.873459369349425 GO:0140996 histone H3 kinase activity 3/235 357/18639 0.00840336134453781 0.666511711067406 0.831017793688198 0.874869629255275 GO:0004713 protein tyrosine kinase activity 1/235 140/18639 0.00714285714285714 0.566534954407295 0.831873264645374 0.874869629255275 GO:0035173 histone kinase activity 3/235 360/18639 0.00833333333333333 0.660957446808511 0.83521997778765 0.874869629255275 GO:0020037 heme binding 1/235 142/18639 0.00704225352112676 0.558555588852263 0.83611780576778 0.874869629255275 GO:0003713 transcription coactivator activity 2/235 256/18639 0.0078125 0.619647606382979 0.836130014675706 0.874869629255275 GO:0022843 voltage-gated monoatomic cation channel activity 1/235 143/18639 0.00699300699300699 0.554649605713435 0.838199890194691 0.875345550068444 GO:0008194 UDP-glycosyltransferase activity 1/235 145/18639 0.00689655172413793 0.546999266324285 0.842285367146228 0.877920517294723 GO:0015293 symporter activity 1/235 146/18639 0.00684931506849315 0.543252696006995 0.844289419202065 0.87832027870925 GO:0016757 glycosyltransferase activity 2/235 267/18639 0.00749063670411985 0.594119053311021 0.85299649956191 0.885678357782673 GO:0046906 tetrapyrrole binding 1/235 152/18639 0.00657894736842105 0.521808510638298 0.855792254204735 0.886882221374697 GO:0005506 iron ion binding 1/235 154/18639 0.00649350649350649 0.515031776733904 0.859435282717496 0.888957868765043 GO:0140297 DNA-binding transcription factor binding 4/235 488/18639 0.00819672131147541 0.650122078828043 0.866975152426405 0.895048633552593 GO:0030246 carbohydrate binding 2/235 280/18639 0.00714285714285714 0.566534954407295 0.870888042007136 0.89737893301876 GO:0015081 sodium ion transmembrane transporter activity 1/235 164/18639 0.00609756097560976 0.483627400103788 0.876320749802119 0.901263465640889 GO:0016874 ligase activity 1/235 167/18639 0.00598802395209581 0.474939482736654 0.880980781086886 0.904340119979342 GO:0008201 heparin binding 1/235 172/18639 0.00581395348837209 0.461133102424542 0.888362151869071 0.908215200184467 GO:0005244 voltage-gated monoatomic ion channel activity 1/235 173/18639 0.00578034682080925 0.458467593161973 0.889782788372605 0.908215200184467 GO:0140030 modification-dependent protein binding 1/235 173/18639 0.00578034682080925 0.458467593161973 0.889782788372605 0.908215200184467 GO:0004252 serine-type endopeptidase activity 1/235 176/18639 0.00568181818181818 0.450652804642166 0.89393759036762 0.910740928532425 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/235 181/18639 0.00552486187845304 0.438203832138239 0.900518526880968 0.91572428061817 GO:0031406 carboxylic acid binding 1/235 187/18639 0.0053475935828877 0.424143816133804 0.907881033571883 0.921482247557978 GO:0043177 organic acid binding 1/235 189/18639 0.00529100529100529 0.419655521783181 0.910212562384241 0.92212188563039 GO:0008236 serine-type peptidase activity 1/235 194/18639 0.00515463917525773 0.408839657819697 0.915787498957272 0.92603885155754 GO:0017171 serine hydrolase activity 1/235 198/18639 0.00505050505050505 0.400580270793037 0.919998176272072 0.928564267298814 GO:0046982 protein heterodimerization activity 2/235 369/18639 0.00542005420054201 0.429891022314479 0.948688599556232 0.955742046393082 GO:1901681 sulfur compound binding 1/235 275/18639 0.00363636363636364 0.288417794970986 0.970261204510664 0.975661545166567 GO:0003779 actin binding 2/235 443/18639 0.00451467268623025 0.358080783824024 0.977009788260081 0.980628343031415 GO:0030371 translation repressor activity 1/235 329/18639 0.00303951367781155 0.241078704003104 0.985180336749325 0.987001372491931 GO:0045182 translation regulator activity 1/235 356/18639 0.00280898876404494 0.222794644991633 0.989546566670194 0.989546566670194