category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	11/83	156/9376	7.9654000617856	IFIT1/SOCS3/EIF2AK2/OAS1/MX2/MX1/IRF7/CXCL10/OAS2/PIK3R2/FAS	8.2906698275694
Human Diseases	Infectious disease: viral	hsa05162	Measles	10/83	136/9376	8.30616583982991	EIF2AK2/FOS/OAS1/IFIH1/MX2/MX1/IRF7/OAS2/PIK3R2/FAS	8.11091238743399
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	11/83	173/9376	7.18267288808413	SOCS3/EIF2AK2/OAS1/IFIH1/MX2/MX1/IRF7/CXCL10/OAS2/PIK3R2/FAS	7.75677735393055
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	12/83	238/9376	5.69565657588337	EIF2AK2/FOS/OAS1/IFIH1/RPL17/MX2/ISG15/MX1/RPS10/CXCL10/OAS2/PIK3R2	6.93435296831568
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	9/83	180/9376	5.64819277108434	SOCS3/EIF2AK2/OAS1/IFIH1/IRF7/SRSF6/OAS2/PIK3R2/FAS	5.95069399587196
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	8/83	205/9376	4.40834557743168	EIF2AK2/OAS1/ISG15/IRF7/CXCL10/OAS2/PIK3R2/FAS	4.66293027774715
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	6/83	119/9376	5.69565657588337	SOCS3/FOS/JUNB/CXCL10/PIK3R2/FAS	4.8717095877847
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	6/83	122/9376	5.5555994469682	SOCS1/SOCS3/FOS/IGFBP3/JUNB/PIK3R2	4.7863826450257
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	6/83	142/9376	4.77312065162057	SOCS1/SOCS3/FOS/JUNB/JUND/PIK3R2	4.28150687364923
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	6/83	157/9376	4.31709001611542	SOCS3/FOS/NDUFA7/COX7A1/PIK3R2/FAS	3.96106429381254
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	9/83	333/9376	3.0530771735591	EIF2AK2/HES4/DVL1/MX2/ISG15/MX1/PIK3R2/FAS/COL9A2	3.60510436402626
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	4/83	71/9376	6.36416086882742	SOCS1/SOCS3/FOS/PIK3R2	4.28765166210063
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	4/83	72/9376	6.27576974564926	IFIH1/ISG15/IRF7/CXCL10	4.24682090217514
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	8/83	300/9376	3.01236947791165	PLA2G4E/DUSP8/FOS/DUSP1/JUND/DUSP9/FAS/CACNG8	3.34786410677248
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	6/83	196/9376	3.45807720678633	ZFP36/EIF2AK2/FOS/IRF7/PIK3R2/FAS	3.28661573838792
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	3/83	47/9376	7.21045885670341	SOCS1/SOCS3/PIK3R2	4.03368320856461
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	6/83	224/9376	3.02581755593804	MSX2/ZFP36/FOS/CRTC2/EGR1/PIK3R2	2.90010051015228
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	5/83	163/9376	3.46514893931554	FOS/IFIH1/IRF7/PIK3R2/FAS	3.00042756051942
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	4/83	109/9376	4.14546258428208	FOS/IRF7/CXCL10/PIK3R2	3.12158314319359
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	4/83	109/9376	4.14546258428208	GYS2/SOCS3/CRTC2/PIK3R2	3.12158314319359
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	4/83	138/9376	3.27431464990396	GYS2/SOCS1/SOCS3/PIK3R2	2.54359421697645
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	4/83	144/9376	3.13788487282463	DVL1/DUSP9/KLF4/PIK3R2	2.44323014573857
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	3/83	91/9376	3.72408314576989	FOS/IFITM1/PIK3R2	2.46772531971127
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	3/83	94/9376	3.6052294283517	FOS/JUND/CXCL10	2.39903086704466
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	7/83	388/9376	2.03800770090672	EIF2AK2/NDUFA7/COX7A1/DVL1/PIK3R2/FAS/TUBB8	1.97347496883467
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	3/83	98/9376	3.45807720678633	PLA2G4E/PIK3R2/CFL2	2.3116819888594
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	3/83	99/9376	3.42314713399051	PLA2G4E/PTGER2/PIK3R2	2.29055286836851
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	3/83	99/9376	3.42314713399051	PLA2G4E/FOS/PIK3R2	2.29055286836851
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/83	103/9376	3.29020938121418	FOS/PIK3R2/FAS	2.20866773847783
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	3/83	115/9376	2.94688318491357	KCNQ5/FOS/PIK3R2	1.98521061195086
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	3/83	115/9376	2.94688318491357	FOS/EGR1/JUND	1.98521061195086
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	4/83	187/9376	2.41633915340506	OAS1/IRF7/NLRP1/OAS2	1.84884564363925
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	3/83	122/9376	2.7777997234841	GYS2/CRTC2/PIK3R2	1.86786170335471
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	5/83	275/9376	2.0538882803943	NDUFA7/COX7A1/EGR1/PIK3R2/TUBB8	1.67634375384298
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	2/83	60/9376	3.76546184738956	PLA2G4E/PIK3R2	2.03083795904581
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	4/83	205/9376	2.20417278871584	GYS2/NDUFA7/COX7A1/PIK3R2	1.64741914473749
Metabolism	Glycan biosynthesis and metabolism	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/83	14/9376	8.06884681583477	CHST1	2.50135300260879
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	3/83	137/9376	2.47366106762818	FOS/PIK3R2/FAS	1.64207173621766
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	4/83	214/9376	2.11147393311564	FOS/PIK3R2/FAS/CFL2	1.55438193627459
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	4/83	216/9376	2.09192324854975	FOS/IRF7/PIK3R2/FAS	1.53432714080976
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	2/83	69/9376	3.27431464990396	PLA2G4E/PIK3R2	1.79191313565744
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	3/83	142/9376	2.38656032581028	FOS/DUSP1/PIK3R2	1.57338397412134
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	2/83	73/9376	3.09490014853936	MX2/MX1	1.69808710077523
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	4/83	227/9376	1.99055251844382	FOS/NDUFA7/COX7A1/PIK3R2	1.42774397816606
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	2/83	75/9376	3.01236947791165	PIK3R2/FAS	1.65356110003302
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/83	75/9376	3.01236947791165	IGFBP3/FAS	1.65356110003302
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	3/83	148/9376	2.28980788016933	FOS/DVL1/PIK3R2	1.49468200712738
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	2/83	78/9376	2.89650911337658	FOS/CFL2	1.58947675196976
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	3/83	154/9376	2.20059458613675	PLA2G4E/FOS/CACNG8	1.41968141795568
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	3/83	157/9376	2.15854500805771	DUSP8/PTGER2/GULP1	1.38346298770822
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	3/83	158/9376	2.14488333079152	GRB10/DVL1/PIK3R2	1.37157051244624
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	2/83	83/9376	2.72202061257077	IRF7/CXCL10	1.48917637955433
Metabolism	Glycan biosynthesis and metabolism	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/83	21/9376	5.37923121055651	CHST7	1.89859504249501
Organismal Systems	Sensory system	hsa04742	Taste transduction	2/83	86/9376	2.62706640515551	P2RX2/TAS2R5	1.43249581715894
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	2/83	86/9376	2.62706640515551	ACTN2/CACNG8	1.43249581715894
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/83	22/9376	5.13472070098576	ASPA	1.83487106395528
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	2/83	87/9376	2.59687023957901	COX7A1/CACNG8	1.41413700770864
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	2/83	87/9376	2.59687023957901	FOS/PIK3R2	1.41413700770864
Metabolism	Metabolism of terpenoids and polyketides	hsa00900	Terpenoid backbone biosynthesis	1/83	23/9376	4.91147197485594	IDI2	1.7749061310193
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	3/83	168/9376	2.01721170395869	PLA2G4E/EIF2AK2/FAS	1.25727433371073
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	3/83	168/9376	2.01721170395869	SOCS1/SOCS3/PIK3R2	1.25727433371073
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	2/83	90/9376	2.51030789825971	FOS/PIK3R2	1.36056446656958
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/83	93/9376	2.4293302241223	PLA2G4E/EGR1	1.30911136175718
Metabolism	Lipid metabolism	hsa00592	alpha-Linolenic acid metabolism	1/83	26/9376	4.34476367006488	PLA2G4E	1.61396094642606
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	4/83	268/9376	1.686027692861	DUSP1/NDUFA7/COX7A1/TUBB8	1.07682281636872
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	2/83	99/9376	2.28209808932701	FOS/PIK3R2	1.21194186471108
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/83	101/9376	2.23690802815221	EGR1/PIK3R2	1.18110321555681
Metabolism	Lipid metabolism	hsa00591	Linoleic acid metabolism	1/83	30/9376	3.76546184738956	PLA2G4E	1.43371267956906
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	2/83	106/9376	2.13139349852239	NKX3-1/PIK3R2	1.10706586524725
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	2/83	107/9376	2.11147393311564	GYS2/CRTC2	1.09275158583281
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	3/83	200/9376	1.6944578313253	FOS/FAS/TUBB8	0.938168595060136
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	3/83	204/9376	1.66123316796598	HOXD10/PIK3R2/FAS	0.902369497324541
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/83	115/9376	1.96458878994238	PLA2G4E/DUSP1	0.983578222258598
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	3/83	205/9376	1.65312959153688	EIF2AK2/IRF7/PIK3R2	0.893541361485077
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	2/83	116/9376	1.94765267968425	PLA2G4E/SHANK1	0.970553348052283
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/83	36/9376	3.13788487282463	GYS2	1.21453166580126
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/83	36/9376	3.13788487282463	GALNT9	1.21453166580126
Metabolism	Amino acid metabolism	hsa00250	Alanine, aspartate and glutamate metabolism	1/83	37/9376	3.0530771735591	ASPA	1.18250412560831
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/83	37/9376	3.0530771735591	COMT	1.18250412560831
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/83	37/9376	3.0530771735591	FAS	1.18250412560831
NA	NA	hsa04519	Cadherin signaling	5/83	404/9376	1.39806751759513	CDH16/PCDHGB1/PCDHGA9/DVL1/ATN1	0.772946627126234
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/83	38/9376	2.97273303741281	NMNAT3	1.15154230376958
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/83	38/9376	2.97273303741281	PIK3R2	1.15154230376958
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	2/83	120/9376	1.88273092369478	PIK3R2/ZNF274	0.919716561252768
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/83	39/9376	2.89650911337658	FAS	1.12158004530386
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	2/83	122/9376	1.85186648232273	FOS/PIK3R2	0.895021389464377
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	3/83	217/9376	1.56171228693576	FOS/KLF4/PIK3R2	0.791163926177186
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/83	125/9376	1.80742168674699	PIK3R2/CERS2	0.85883115768908
Organismal Systems	Immune system	hsa04611	Platelet activation	2/83	126/9376	1.7930770701855	PLA2G4E/PIK3R2	0.846986553261596
Genetic Information Processing	Translation	hsa03010	Ribosome	3/83	222/9376	1.52653858677955	MRPL39/RPL17/RPS10	0.750322469896951
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/83	130/9376	1.73790546802595	FOS/PIK3R2	0.80064901921586
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	3/83	226/9376	1.49952020471266	FOS/PTGER2/PIK3R2	0.718362160137255
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/83	44/9376	2.56736035049288	MGAT2	0.98481475143045
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/83	44/9376	2.56736035049288	FAS	0.98481475143045
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	3/83	227/9376	1.49291438883286	PTGER2/PIK3R2/FAS	0.710467680717364
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	2/83	133/9376	1.69870459280732	PIK3R2/FAS	0.766936942573493
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	2/83	133/9376	1.69870459280732	FOS/COMT	0.766936942573493
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/83	45/9376	2.51030789825971	FAS	0.959741714592111
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	3/83	233/9376	1.45447024148095	PDLIM3/ACTN2/COL9A2	0.663874163970452
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	2/83	138/9376	1.63715732495198	NDUFA7/COX7A1	0.712596951842385
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/83	138/9376	1.63715732495198	FOS/PIK3R2	0.712596951842385
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/83	48/9376	2.35341365461847	PIK3R2	0.888389914538236
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	2/83	139/9376	1.62537921470053	FOS/PIK3R2	0.701991877236573
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	1/83	49/9376	2.30538480452422	GALNT9	0.865789511659749
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	2/83	142/9376	1.59104021720686	SOCS1/SOCS3	0.670676340945369
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/83	51/9376	2.21497755728798	PLA2G4E	0.822196529844343
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	2/83	144/9376	1.56894243641232	DAB1/PIK3R2	0.650202136467684
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/83	52/9376	2.17238183503244	PLA2G4E	0.801154609977422
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	3/83	248/9376	1.36649825106879	FOS/RHOB/TUBB8	0.552785505625244
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	2/83	149/9376	1.51629336136492	PLA2G4E/PIK3R2	0.600352233277565
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/83	54/9376	2.09192324854975	FAS	0.760468376998369
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	2/83	150/9376	1.50618473895582	DVL1/PIK3R2	0.590601665863392
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/83	55/9376	2.0538882803943	CERS2	0.740783638460849
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/83	56/9376	2.01721170395869	MGAT2	0.721512935448684
NA	NA	hsa04518	Integrin signaling	2/83	154/9376	1.4670630574245	PIK3R2/COL9A2	0.552293631252144
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	4/83	362/9376	1.24821939692472	GYS2/CRTC2/PIK3R2/COL9A2	0.455174517303113
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	2/83	157/9376	1.43903000537181	IGFBP3/PIK3R2	0.524262552340117
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/83	59/9376	1.91464161731672	PIK3R2	0.666017487200644
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/83	59/9376	1.91464161731672	PIK3R2	0.666017487200644
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	4/83	368/9376	1.22786799371399	NDUFA7/COX7A1/ANG/TUBB8	0.421443892953587
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/83	60/9376	1.88273092369478	PLA2G4E	0.648240173392782
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	5/83	480/9376	1.17670682730924	NDUFA7/COX7A1/DVL1/FAS/TUBB8	0.37559800494817
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/83	62/9376	1.82199766809172	PIK3R2	0.613684323280397
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/83	62/9376	1.82199766809172	DVL1	0.613684323280397
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/83	63/9376	1.7930770701855	AASS	0.596880763619514
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/83	63/9376	1.7930770701855	PLA2G4E	0.596880763619514
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/83	63/9376	1.7930770701855	DVL1	0.596880763619514
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/83	65/9376	1.73790546802595	PIK3R2	0.564164765831236
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/83	66/9376	1.71157356699525	COMT	0.548231076570602
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	2/83	170/9376	1.32898653437279	DVL1/PIK3R2	0.409085243174047
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/83	68/9376	1.66123316796598	ALDH1A2	0.517163200974939
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/83	68/9376	1.66123316796598	PIK3R2	0.517163200974939
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/83	69/9376	1.63715732495198	PTGER2	0.502010827793782
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/83	69/9376	1.63715732495198	FOS	0.502010827793782
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/83	70/9376	1.61376936316695	SOCS3	0.487101445280493
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/83	70/9376	1.61376936316695	PIK3R2	0.487101445280493
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/83	71/9376	1.59104021720686	PIK3R2	0.47242702663935
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	2/83	178/9376	1.26925680249086	DVL1/CACYBP	0.342749396246404
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/83	73/9376	1.54745007426968	PIK3R2	0.443752849072042
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/83	73/9376	1.54745007426968	PIK3R2	0.443752849072042
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	2/83	184/9376	1.22786799371399	PIK3R2/CFL2	0.295008105113736
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/83	76/9376	1.4863665187064	PIK3R2	0.402323784897143
NA	NA	hsa04517	IgSF CAM signaling	3/83	299/9376	1.13341660958214	PMP22/PIK3R2/TUBB8	0.221575145062674
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/83	77/9376	1.4670630574245	PIK3R2	0.388910324352273
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/83	77/9376	1.4670630574245	PIK3R2	0.388910324352273
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/83	78/9376	1.44825455668829	BTG2	0.375685089934536
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/83	78/9376	1.44825455668829	PIK3R2	0.375685089934536
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/83	78/9376	1.44825455668829	FOS	0.375685089934536
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/83	80/9376	1.41204819277108	PIK3R2	0.34977733579293
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	2/83	193/9376	1.17060990074287	CXCL10/PIK3R2	0.226327490727535
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	3/83	308/9376	1.10029729306838	NDUFA7/COX7A1/TUBB8	0.169143584640688
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/83	201/9376	1.12401846190733	IGFBP3/NFKBIZ	0.16796857930738
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/83	86/9376	1.31353320257775	PIK3R2	0.276039748476123
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/83	86/9376	1.31353320257775	FFAR1	0.276039748476123
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	2/83	203/9376	1.112944388391	PIK3R2/COL9A2	0.153745954130943
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/83	89/9376	1.26925680249086	COL9A2	0.241196321721135
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/83	89/9376	1.26925680249086	TUBB8	0.241196321721135
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	3/83	323/9376	1.04919989555746	HOXD10/SOCS1/PIK3R2	0.085038560034893
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/83	90/9376	1.25515394912985	PIK3R2	0.229856042659247
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/83	93/9376	1.21466511206115	FOS	0.196609945294267
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/83	93/9376	1.21466511206115	PIK3R2	0.196609945294267
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/83	95/9376	1.18909321496512	FOS	0.175060061986473
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/83	97/9376	1.16457582908955	FOS	0.153974232227658
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/83	98/9376	1.15269240226211	PIK3R2	0.143598531067489
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/83	99/9376	1.1410490446635	CACNG8	0.133330861053644
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/83	100/9376	1.12963855421687	CXCL10	0.123168747405782
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/83	101/9376	1.11845401407611	DVL1	0.113109797767182
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	1/83	103/9376	1.09673646040473	COL9A2	0.0932922120497046
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	1/83	103/9376	1.09673646040473	PIK3R2	0.0932922120497046
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/83	104/9376	1.08619091751622	PLA2G4E	0.0835291722810465
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/83	105/9376	1.0758462421113	PIK3R2	0.0738604829181633
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/83	105/9376	1.0758462421113	CACNG8	0.0738604829181633
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	2/83	232/9376	0.973826339842127	PIK3R2/CFL2	-0.0381493426237441
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	2/83	235/9376	0.961394514227121	NDUFA7/COX7A1	-0.0566412480330985
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/83	109/9376	1.03636564607052	FOS	0.0360895686161819
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/83	110/9376	1.02694414019715	PIK3R2	0.026863416155912
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/83	110/9376	1.02694414019715	GREM1	0.026863416155912
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/83	110/9376	1.02694414019715	PIK3R2	0.026863416155912
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	2/83	238/9376	0.949276095980561	PLA2G4E/PIK3R2	-0.0749069802524021
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/83	112/9376	1.00860585197935	SOCS1	0.00865865281031728
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	3/83	370/9376	0.91592315206773	PTGER2/P2RX2/CORT	-0.155940178863238
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/83	116/9376	0.973826339842127	PIK3R2	-0.0268061643697035
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/83	117/9376	0.965503037792195	CDK2AP1	-0.0354844809984004
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/83	122/9376	0.925933241161367	PIK3R2	-0.0778189244259545
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/83	133/9376	0.84935229640366	PIK3R2	-0.165359281148674
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/83	134/9376	0.843013846430498	PLA2G4E	-0.172972666937338
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/83	140/9376	0.806884681583477	EGR1	-0.217563229108324
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/83	144/9376	0.784471218206158	FAS	-0.246311868167758
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	1/83	149/9376	0.758146680682461	NDUFA7	-0.281229996825873
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/83	298/9376	0.758146680682461	CXCL10/FAS	-0.40096993568967
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/83	154/9376	0.733531528712252	NMNAT3	-0.315094155451391
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/83	154/9376	0.733531528712252	CACNG8	-0.315094155451391
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	1/83	155/9376	0.728799067236689	TUBB8	-0.321747167874312
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/83	155/9376	0.728799067236689	DVL1	-0.321747167874312
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/83	157/9376	0.719515002685903	DVL1	-0.334937883027989
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/83	169/9376	0.668425180009981	PIK3R2	-0.411066929543566
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/83	170/9376	0.664493267186393	YBX3	-0.417192921410155
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/83	174/9376	0.649217559894751	FBXO6	-0.441385508413124
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/83	194/9376	0.582287914544777	TUBB8	-0.55559199175502
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/83	195/9376	0.579301822675317	PIK3R2	-0.561034616075638
NA	NA	hsa04082	Neuroactive ligand signaling	1/83	199/9376	0.567657564933099	P2RX2	-0.582573535982376
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/83	212/9376	0.532848374630598	PIK3R2	-0.650174556729813
NA	NA	hsa04081	Hormone signaling	1/83	219/9376	0.515816691423227	PIK3R2	-0.685175743791735
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/83	243/9376	0.464871833011057	SRSF6	-0.798731725481571
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	1/83	250/9376	0.451855421686747	LAMP5	-0.830178746568823
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	1/83	253/9376	0.446497452259631	PIK3R2	-0.843446932736701
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/83	254/9376	0.444739588274357	P2RX2	-0.84784263312899