ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/164	10/18639	0.3	34.0957317073171	7.66992868341979e-05	0.0314467076020211
GO:0003725	double-stranded RNA binding	5/164	75/18639	0.0666666666666667	7.57682926829268	0.000521132222205618	0.106832105552152
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	3/164	26/18639	0.115384615384615	13.1137429643527	0.00149856145921245	0.204803399425701
GO:0070566	adenylyltransferase activity	3/164	30/18639	0.1	11.365243902439	0.00228058307862608	0.233759765559173
GO:0004715	non-membrane spanning protein tyrosine kinase activity	3/164	45/18639	0.0666666666666667	7.57682926829268	0.00724000761199229	0.444818113201616
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/164	17/18639	0.117647058823529	13.37087517934	0.00959560131890846	0.444818113201616
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	10/164	484/18639	0.0206611570247934	2.34819088893368	0.0107034593463816	0.444818113201616
GO:0005246	calcium channel regulator activity	3/164	53/18639	0.0566037735849057	6.43315692590888	0.0113577011238317	0.444818113201616
GO:0001216	DNA-binding transcription activator activity	10/164	491/18639	0.0203665987780041	2.31471362575133	0.0117477135796767	0.444818113201616
GO:0016505	peptidase activator activity involved in apoptotic process	2/164	20/18639	0.1	11.365243902439	0.0131764784005878	0.444818113201616
GO:0099186	structural constituent of postsynapse	2/164	23/18639	0.0869565217391304	9.88282078472959	0.0172462548361654	0.444818113201616
GO:1990841	promoter-specific chromatin binding	3/164	68/18639	0.0441176470588235	5.01407819225251	0.0220912445781304	0.444818113201616
GO:0050698	proteoglycan sulfotransferase activity	2/164	28/18639	0.0714285714285714	8.11803135888502	0.0250408737255018	0.444818113201616
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	2/164	28/18639	0.0714285714285714	8.11803135888502	0.0250408737255018	0.444818113201616
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	2/164	29/18639	0.0689655172413793	7.8380992430614	0.0267427332472843	0.444818113201616
GO:0035591	signaling adaptor activity	4/164	129/18639	0.0310077519379845	3.5241066364152	0.0272623509735766	0.444818113201616
GO:0098918	structural constituent of synapse	2/164	30/18639	0.0666666666666667	7.57682926829268	0.0284900296879028	0.444818113201616
GO:0003724	RNA helicase activity	3/164	77/18639	0.038961038961039	4.42801710484637	0.030463696749058	0.444818113201616
GO:0016779	nucleotidyltransferase activity	4/164	136/18639	0.0294117647058824	3.34271879483501	0.0322260770770044	0.444818113201616
GO:0008186	ATP-dependent activity, acting on RNA	3/164	79/18639	0.0379746835443038	4.3159154059895	0.0325206934865585	0.444818113201616
GO:0033192	calmodulin-dependent protein phosphatase activity	3/164	81/18639	0.037037037037037	4.20934959349593	0.0346485358471499	0.444818113201616
GO:0140791	histone H2AXS140 phosphatase activity	3/164	81/18639	0.037037037037037	4.20934959349593	0.0346485358471499	0.444818113201616
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	3/164	81/18639	0.037037037037037	4.20934959349593	0.0346485358471499	0.444818113201616
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	3/164	81/18639	0.037037037037037	4.20934959349593	0.0346485358471499	0.444818113201616
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	3/164	81/18639	0.037037037037037	4.20934959349593	0.0346485358471499	0.444818113201616
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	3/164	81/18639	0.037037037037037	4.20934959349593	0.0346485358471499	0.444818113201616
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	3/164	81/18639	0.037037037037037	4.20934959349593	0.0346485358471499	0.444818113201616
GO:1990439	MAP kinase serine/threonine phosphatase activity	3/164	81/18639	0.037037037037037	4.20934959349593	0.0346485358471499	0.444818113201616
GO:0004713	protein tyrosine kinase activity	4/164	140/18639	0.0285714285714286	3.24721254355401	0.0352851699305192	0.444818113201616
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	3/164	82/18639	0.0365853658536585	4.15801606186794	0.0357389060277368	0.444818113201616
GO:0033549	MAP kinase phosphatase activity	3/164	82/18639	0.0365853658536585	4.15801606186794	0.0357389060277368	0.444818113201616
GO:0005516	calmodulin binding	5/164	207/18639	0.0241545893719807	2.74522799575822	0.0363631214390017	0.444818113201616
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	3/164	83/18639	0.036144578313253	4.10791948280929	0.0368468389419	0.444818113201616
GO:0004860	protein kinase inhibitor activity	3/164	84/18639	0.0357142857142857	4.05901567944251	0.0379722779562355	0.444818113201616
GO:0017018	myosin phosphatase activity	3/164	84/18639	0.0357142857142857	4.05901567944251	0.0379722779562355	0.444818113201616
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	3/164	86/18639	0.0348837209302326	3.9646199659671	0.0402754316241241	0.450889707186981
GO:0019207	kinase regulator activity	6/164	287/18639	0.0209059233449477	2.37600917821025	0.0416781300621185	0.450889707186981
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	3/164	89/18639	0.0337078651685393	3.83098109070978	0.0438598601091341	0.450889707186981
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	3/164	89/18639	0.0337078651685393	3.83098109070978	0.0438598601091341	0.450889707186981
GO:0019210	kinase inhibitor activity	3/164	90/18639	0.0333333333333333	3.78841463414634	0.0450889707186981	0.450889707186981
GO:0140793	histone H2AXY142 phosphatase activity	3/164	90/18639	0.0333333333333333	3.78841463414634	0.0450889707186981	0.450889707186981
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	2/164	40/18639	0.05	5.68262195121951	0.0482655136159291	0.471163347203117
GO:0004725	protein tyrosine phosphatase activity	3/164	98/18639	0.0306122448979592	3.47915629666501	0.0555276420780456	0.49987654420243
GO:0140713	histone chaperone activity	4/164	164/18639	0.024390243902439	2.77201070791196	0.0570651453000923	0.49987654420243
GO:0004722	protein serine/threonine phosphatase activity	3/164	103/18639	0.029126213592233	3.31026521430263	0.0625848746016723	0.49987654420243
GO:0001784	phosphotyrosine residue binding	2/164	47/18639	0.0425531914893617	4.83627400103788	0.0643004362840948	0.49987654420243
GO:0032266	phosphatidylinositol-3-phosphate binding	2/164	48/18639	0.0416666666666667	4.73551829268293	0.06671970377044	0.49987654420243
GO:0038187	pattern recognition receptor activity	2/164	48/18639	0.0416666666666667	4.73551829268293	0.06671970377044	0.49987654420243
GO:0043021	ribonucleoprotein complex binding	4/164	177/18639	0.0225988700564972	2.56841670111616	0.0712873177801944	0.49987654420243
GO:0003924	GTPase activity	6/164	331/18639	0.0181268882175227	2.06016505784393	0.072693743092098	0.49987654420243
GO:1902936	phosphatidylinositol bisphosphate binding	3/164	111/18639	0.027027027027027	3.07168754119974	0.0746919556040483	0.49987654420243
GO:0019887	protein kinase regulator activity	5/164	255/18639	0.0196078431372549	2.22847919655667	0.0750775743127985	0.49987654420243
GO:0030159	signaling receptor complex adaptor activity	2/164	52/18639	0.0384615384615385	4.37124765478424	0.0766891962063271	0.49987654420243
GO:0005544	calcium-dependent phospholipid binding	2/164	53/18639	0.0377358490566038	4.28877128393925	0.079251215621327	0.49987654420243
GO:0008146	sulfotransferase activity	2/164	53/18639	0.0377358490566038	4.28877128393925	0.079251215621327	0.49987654420243
GO:0035401	histone H3Y41 kinase activity	3/164	115/18639	0.0260869565217391	2.96484623541888	0.0811064066845443	0.49987654420243
GO:0140801	histone H2AXY142 kinase activity	3/164	115/18639	0.0260869565217391	2.96484623541888	0.0811064066845443	0.49987654420243
GO:0004955	prostaglandin receptor activity	1/164	10/18639	0.1	11.365243902439	0.0846038602773245	0.49987654420243
GO:0005031	tumor necrosis factor receptor activity	1/164	10/18639	0.1	11.365243902439	0.0846038602773245	0.49987654420243
GO:0008140	cAMP response element binding protein binding	1/164	10/18639	0.1	11.365243902439	0.0846038602773245	0.49987654420243
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/164	10/18639	0.1	11.365243902439	0.0846038602773245	0.49987654420243
GO:0015203	polyamine transmembrane transporter activity	1/164	10/18639	0.1	11.365243902439	0.0846038602773245	0.49987654420243
GO:0031996	thioesterase binding	1/164	10/18639	0.1	11.365243902439	0.0846038602773245	0.49987654420243
GO:0140597	protein carrier chaperone	4/164	188/18639	0.0212765957446809	2.41813700051894	0.0846052861028115	0.49987654420243
GO:0016504	peptidase activator activity	2/164	57/18639	0.0350877192982456	3.98780487804878	0.0897578500588899	0.49987654420243
GO:0004954	prostanoid receptor activity	1/164	11/18639	0.0909090909090909	10.3320399113082	0.0926625304643726	0.49987654420243
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/164	11/18639	0.0909090909090909	10.3320399113082	0.0926625304643726	0.49987654420243
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/164	11/18639	0.0909090909090909	10.3320399113082	0.0926625304643726	0.49987654420243
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/164	11/18639	0.0909090909090909	10.3320399113082	0.0926625304643726	0.49987654420243
GO:0045309	protein phosphorylated amino acid binding	2/164	59/18639	0.0338983050847458	3.85262505167425	0.0951573175274769	0.49987654420243
GO:0004300	enoyl-CoA hydratase activity	1/164	12/18639	0.0833333333333333	9.47103658536585	0.100650685124231	0.49987654420243
GO:0008603	cAMP-dependent protein kinase regulator activity	1/164	12/18639	0.0833333333333333	9.47103658536585	0.100650685124231	0.49987654420243
GO:0035251	UDP-glucosyltransferase activity	1/164	12/18639	0.0833333333333333	9.47103658536585	0.100650685124231	0.49987654420243
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	3/164	128/18639	0.0234375	2.66372903963415	0.103500951100431	0.49987654420243
GO:0003714	transcription corepressor activity	4/164	204/18639	0.0196078431372549	2.22847919655667	0.105971555327544	0.49987654420243
GO:0035091	phosphatidylinositol binding	5/164	284/18639	0.0176056338028169	2.00092322226039	0.106230499731773	0.49987654420243
GO:0005035	death receptor activity	1/164	13/18639	0.0769230769230769	8.74249530956848	0.108568937534154	0.49987654420243
GO:0005172	vascular endothelial growth factor receptor binding	1/164	13/18639	0.0769230769230769	8.74249530956848	0.108568937534154	0.49987654420243
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/164	13/18639	0.0769230769230769	8.74249530956848	0.108568937534154	0.49987654420243
GO:0031432	titin binding	1/164	13/18639	0.0769230769230769	8.74249530956848	0.108568937534154	0.49987654420243
GO:0031994	insulin-like growth factor I binding	1/164	13/18639	0.0769230769230769	8.74249530956848	0.108568937534154	0.49987654420243
GO:0046974	histone H3K9 methyltransferase activity	1/164	13/18639	0.0769230769230769	8.74249530956848	0.108568937534154	0.49987654420243
GO:0051011	microtubule minus-end binding	1/164	13/18639	0.0769230769230769	8.74249530956848	0.108568937534154	0.49987654420243
GO:0071837	HMG box domain binding	1/164	13/18639	0.0769230769230769	8.74249530956848	0.108568937534154	0.49987654420243
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/164	13/18639	0.0769230769230769	8.74249530956848	0.108568937534154	0.49987654420243
GO:0051015	actin filament binding	4/164	209/18639	0.0191387559808612	2.17516629711752	0.113108007126943	0.49987654420243
GO:0044548	S100 protein binding	1/164	14/18639	0.0714285714285714	8.11803135888502	0.116417895670329	0.49987654420243
GO:0005525	GTP binding	6/164	378/18639	0.0158730158730159	1.80400696864111	0.117251983620018	0.49987654420243
GO:0140789	histone phosphatase activity	3/164	136/18639	0.0220588235294118	2.50703909612626	0.118366242601151	0.49987654420243
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	2/164	68/18639	0.0294117647058824	3.34271879483501	0.120510730007486	0.49987654420243
GO:0004129	cytochrome-c oxidase activity	1/164	15/18639	0.0666666666666667	7.57682926829268	0.124198162253419	0.49987654420243
GO:0004953	icosanoid receptor activity	1/164	15/18639	0.0666666666666667	7.57682926829268	0.124198162253419	0.49987654420243
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/164	15/18639	0.0666666666666667	7.57682926829268	0.124198162253419	0.49987654420243
GO:0031386	protein tag activity	1/164	15/18639	0.0666666666666667	7.57682926829268	0.124198162253419	0.49987654420243
GO:0051371	muscle alpha-actinin binding	1/164	15/18639	0.0666666666666667	7.57682926829268	0.124198162253419	0.49987654420243
GO:0141047	molecular tag activity	1/164	15/18639	0.0666666666666667	7.57682926829268	0.124198162253419	0.49987654420243
GO:0016782	transferase activity, transferring sulphur-containing groups	2/164	70/18639	0.0285714285714286	3.24721254355401	0.126352311986515	0.49987654420243
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/164	16/18639	0.0625	7.10327743902439	0.131910334793714	0.49987654420243
GO:0005159	insulin-like growth factor receptor binding	1/164	16/18639	0.0625	7.10327743902439	0.131910334793714	0.49987654420243
GO:0016675	oxidoreductase activity, acting on a heme group of donors	1/164	16/18639	0.0625	7.10327743902439	0.131910334793714	0.49987654420243
GO:0008194	UDP-glycosyltransferase activity	3/164	145/18639	0.0206896551724138	2.35142977291842	0.135971862866853	0.49987654420243
GO:0004029	aldehyde dehydrogenase (NAD+) activity	1/164	17/18639	0.0588235294117647	6.68543758967001	0.139555005635889	0.49987654420243
GO:0004549	tRNA-specific ribonuclease activity	1/164	17/18639	0.0588235294117647	6.68543758967001	0.139555005635889	0.49987654420243
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/164	17/18639	0.0588235294117647	6.68543758967001	0.139555005635889	0.49987654420243
GO:0045125	bioactive lipid receptor activity	1/164	17/18639	0.0588235294117647	6.68543758967001	0.139555005635889	0.49987654420243
GO:0045236	CXCR chemokine receptor binding	1/164	17/18639	0.0588235294117647	6.68543758967001	0.139555005635889	0.49987654420243
GO:0019003	GDP binding	2/164	75/18639	0.0266666666666667	3.03073170731707	0.141236658350799	0.49987654420243
GO:0019001	guanyl nucleotide binding	6/164	400/18639	0.015	1.70478658536585	0.141935211477653	0.49987654420243
GO:0032561	guanyl ribonucleotide binding	6/164	400/18639	0.015	1.70478658536585	0.141935211477653	0.49987654420243
GO:0003746	translation elongation factor activity	1/164	18/18639	0.0555555555555556	6.3140243902439	0.147132762003396	0.49987654420243
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	1/164	18/18639	0.0555555555555556	6.3140243902439	0.147132762003396	0.49987654420243
GO:0004706	JUN kinase kinase kinase activity	1/164	18/18639	0.0555555555555556	6.3140243902439	0.147132762003396	0.49987654420243
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/164	18/18639	0.0555555555555556	6.3140243902439	0.147132762003396	0.49987654420243
GO:0098641	cadherin binding involved in cell-cell adhesion	1/164	18/18639	0.0555555555555556	6.3140243902439	0.147132762003396	0.49987654420243
GO:0003712	transcription coregulator activity	7/164	495/18639	0.0141414141414141	1.60720620842572	0.147266022574953	0.49987654420243
GO:0000510	H3-H4 histone complex chaperone activity	3/164	151/18639	0.0198675496688742	2.25799547730577	0.148179408542579	0.49987654420243
GO:0140584	chromatin extrusion motor activity	3/164	151/18639	0.0198675496688742	2.25799547730577	0.148179408542579	0.49987654420243
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	3/164	151/18639	0.0198675496688742	2.25799547730577	0.148179408542579	0.49987654420243
GO:0140849	ATP-dependent H2AZ histone chaperone activity	3/164	151/18639	0.0198675496688742	2.25799547730577	0.148179408542579	0.49987654420243
GO:0015616	DNA translocase activity	3/164	152/18639	0.0197368421052632	2.24314024390244	0.15024795650622	0.49987654420243
GO:0140674	ATP-dependent histone chaperone activity	3/164	152/18639	0.0197368421052632	2.24314024390244	0.15024795650622	0.49987654420243
GO:0061775	cohesin loader activity	3/164	153/18639	0.0196078431372549	2.22847919655667	0.15232583029761	0.49987654420243
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/164	19/18639	0.0526315789473684	5.98170731707317	0.154644186042462	0.49987654420243
GO:0005520	insulin-like growth factor binding	1/164	19/18639	0.0526315789473684	5.98170731707317	0.154644186042462	0.49987654420243
GO:0016918	retinal binding	1/164	19/18639	0.0526315789473684	5.98170731707317	0.154644186042462	0.49987654420243
GO:0046527	glucosyltransferase activity	1/164	19/18639	0.0526315789473684	5.98170731707317	0.154644186042462	0.49987654420243
GO:0004386	helicase activity	3/164	155/18639	0.0193548387096774	2.19972462627852	0.156508992210974	0.49987654420243
GO:0001614	purinergic nucleotide receptor activity	1/164	20/18639	0.05	5.68262195121951	0.162089854865718	0.49987654420243
GO:0005326	neurotransmitter transmembrane transporter activity	1/164	20/18639	0.05	5.68262195121951	0.162089854865718	0.49987654420243
GO:0016502	nucleotide receptor activity	1/164	20/18639	0.05	5.68262195121951	0.162089854865718	0.49987654420243
GO:0140658	ATP-dependent chromatin remodeler activity	3/164	158/18639	0.0189873417721519	2.15795770299475	0.16285016353236	0.49987654420243
GO:0003689	DNA clamp loader activity	3/164	160/18639	0.01875	2.13098323170732	0.167120262482955	0.49987654420243
GO:0099106	ion channel regulator activity	3/164	160/18639	0.01875	2.13098323170732	0.167120262482955	0.49987654420243
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/164	21/18639	0.0476190476190476	5.41202090592335	0.169470340595458	0.49987654420243
GO:0010314	phosphatidylinositol-5-phosphate binding	1/164	21/18639	0.0476190476190476	5.41202090592335	0.169470340595458	0.49987654420243
GO:0036122	BMP binding	1/164	21/18639	0.0476190476190476	5.41202090592335	0.169470340595458	0.49987654420243
GO:0061891	calcium ion sensor activity	1/164	21/18639	0.0476190476190476	5.41202090592335	0.169470340595458	0.49987654420243
GO:0070182	DNA polymerase binding	1/164	21/18639	0.0476190476190476	5.41202090592335	0.169470340595458	0.49987654420243
GO:0072542	protein phosphatase activator activity	1/164	21/18639	0.0476190476190476	5.41202090592335	0.169470340595458	0.49987654420243
GO:0008970	phospholipase A1 activity	1/164	22/18639	0.0454545454545455	5.1660199556541	0.176786210406519	0.504154963995643
GO:0033038	bitter taste receptor activity	1/164	22/18639	0.0454545454545455	5.1660199556541	0.176786210406519	0.504154963995643
GO:0061133	endopeptidase activator activity	1/164	22/18639	0.0454545454545455	5.1660199556541	0.176786210406519	0.504154963995643
GO:0140784	metal ion sensor activity	1/164	22/18639	0.0454545454545455	5.1660199556541	0.176786210406519	0.504154963995643
GO:0140104	molecular carrier activity	4/164	249/18639	0.0160642570281124	1.82574199235968	0.177069060525299	0.504154963995643
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/164	23/18639	0.0434782608695652	4.94141039236479	0.184038026568808	0.50434855841613
GO:0005158	insulin receptor binding	1/164	23/18639	0.0434782608695652	4.94141039236479	0.184038026568808	0.50434855841613
GO:0008171	O-methyltransferase activity	1/164	23/18639	0.0434782608695652	4.94141039236479	0.184038026568808	0.50434855841613
GO:0140103	catalytic activity, acting on a glycoprotein	1/164	23/18639	0.0434782608695652	4.94141039236479	0.184038026568808	0.50434855841613
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/164	23/18639	0.0434782608695652	4.94141039236479	0.184038026568808	0.50434855841613
GO:0016247	channel regulator activity	3/164	168/18639	0.0178571428571429	2.02950783972125	0.184517765274194	0.50434855841613
GO:0141108	transporter regulator activity	3/164	170/18639	0.0176470588235294	2.005631276901	0.188940905110168	0.512436614775657
GO:0019957	C-C chemokine binding	1/164	24/18639	0.0416666666666667	4.73551829268293	0.191226346489453	0.512436614775657
GO:0035035	histone acetyltransferase binding	1/164	24/18639	0.0416666666666667	4.73551829268293	0.191226346489453	0.512436614775657
GO:0003779	actin binding	6/164	443/18639	0.0135440180586907	1.53931068656059	0.196316840207999	0.517081434336915
GO:0051219	phosphoprotein binding	2/164	93/18639	0.021505376344086	2.4441384736428	0.197327726634875	0.517081434336915
GO:0004709	MAP kinase kinase kinase activity	1/164	25/18639	0.04	4.54609756097561	0.198351722754601	0.517081434336915
GO:0019211	phosphatase activator activity	1/164	25/18639	0.04	4.54609756097561	0.198351722754601	0.517081434336915
GO:0004721	phosphoprotein phosphatase activity	3/164	175/18639	0.0171428571428571	1.9483275261324	0.200115931703457	0.517081434336915
GO:0016410	N-acyltransferase activity	2/164	94/18639	0.0212765957446809	2.41813700051894	0.200526702584316	0.517081434336915
GO:0043548	phosphatidylinositol 3-kinase binding	1/164	26/18639	0.0384615384615385	4.37124765478424	0.20541470317086	0.523105765838835
GO:0070412	R-SMAD binding	1/164	26/18639	0.0384615384615385	4.37124765478424	0.20541470317086	0.523105765838835
GO:0016757	glycosyltransferase activity	4/164	267/18639	0.0149812734082397	1.70265826253768	0.20915536443139	0.529343823560924
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/164	27/18639	0.037037037037037	4.20934959349593	0.212415830806382	0.531039577015955
GO:0035255	ionotropic glutamate receptor binding	1/164	27/18639	0.037037037037037	4.20934959349593	0.212415830806382	0.531039577015955
GO:0008527	taste receptor activity	1/164	28/18639	0.0357142857142857	4.05901567944251	0.219355644031599	0.538537808700334
GO:0051019	mitogen-activated protein kinase binding	1/164	28/18639	0.0357142857142857	4.05901567944251	0.219355644031599	0.538537808700334
GO:0051393	alpha-actinin binding	1/164	28/18639	0.0357142857142857	4.05901567944251	0.219355644031599	0.538537808700334
GO:1901981	phosphatidylinositol phosphate binding	3/164	185/18639	0.0162162162162162	1.84301252471984	0.222911594367047	0.543248495298715
GO:0005126	cytokine receptor binding	4/164	275/18639	0.0145454545454545	1.65312638580931	0.22392437976947	0.543248495298715
GO:0008017	microtubule binding	4/164	276/18639	0.0144927536231884	1.64713679745493	0.225789805099268	0.544551882886471
GO:0001968	fibronectin binding	1/164	30/18639	0.0333333333333333	3.78841463414634	0.233053457486222	0.552323222944225
GO:0035925	mRNA 3'-UTR AU-rich region binding	1/164	30/18639	0.0333333333333333	3.78841463414634	0.233053457486222	0.552323222944225
GO:0048019	receptor antagonist activity	1/164	30/18639	0.0333333333333333	3.78841463414634	0.233053457486222	0.552323222944225
GO:0008013	beta-catenin binding	2/164	106/18639	0.0188679245283019	2.14438564196963	0.239297269764441	0.552377132837947
GO:0005184	neuropeptide hormone activity	1/164	31/18639	0.032258064516129	3.6662077104642	0.239812511329645	0.552377132837947
GO:0047499	calcium-independent phospholipase A2 activity	1/164	31/18639	0.032258064516129	3.6662077104642	0.239812511329645	0.552377132837947
GO:0070273	phosphatidylinositol-4-phosphate binding	1/164	31/18639	0.032258064516129	3.6662077104642	0.239812511329645	0.552377132837947
GO:0072349	modified amino acid transmembrane transporter activity	1/164	31/18639	0.032258064516129	3.6662077104642	0.239812511329645	0.552377132837947
GO:0019888	protein phosphatase regulator activity	2/164	107/18639	0.0186915887850467	2.1243446546615	0.242550253794155	0.55504246206916
GO:0047498	calcium-dependent phospholipase A2 activity	1/164	32/18639	0.03125	3.5516387195122	0.24651235806986	0.55504246206916
GO:0160041	neuropeptide activity	1/164	32/18639	0.03125	3.5516387195122	0.24651235806986	0.55504246206916
GO:0016758	hexosyltransferase activity	3/164	197/18639	0.0152284263959391	1.73074780240188	0.25089741945193	0.55504246206916
GO:0015631	tubulin binding	5/164	385/18639	0.012987012987013	1.47600570161546	0.251778020852459	0.55504246206916
GO:0019956	chemokine binding	1/164	33/18639	0.0303030303030303	3.4440133037694	0.253153513187641	0.55504246206916
GO:0030296	protein tyrosine kinase activator activity	1/164	33/18639	0.0303030303030303	3.4440133037694	0.253153513187641	0.55504246206916
GO:0071889	14-3-3 protein binding	1/164	33/18639	0.0303030303030303	3.4440133037694	0.253153513187641	0.55504246206916
GO:0140416	transcription regulator inhibitor activity	1/164	33/18639	0.0303030303030303	3.4440133037694	0.253153513187641	0.55504246206916
GO:0005200	structural constituent of cytoskeleton	2/164	112/18639	0.0178571428571429	2.02950783972125	0.258839307127488	0.560483999780675
GO:0043022	ribosome binding	2/164	112/18639	0.0178571428571429	2.02950783972125	0.258839307127488	0.560483999780675
GO:0008376	acetylgalactosaminyltransferase activity	1/164	34/18639	0.0294117647058824	3.34271879483501	0.25973648770324	0.560483999780675
GO:0001664	G protein-coupled receptor binding	4/164	297/18639	0.0134680134680135	1.53067257945307	0.265801671995706	0.562718212206433
GO:0000175	3'-5'-RNA exonuclease activity	1/164	35/18639	0.0285714285714286	3.24721254355401	0.266261788214751	0.562718212206433
GO:0004623	phospholipase A2 activity	1/164	35/18639	0.0285714285714286	3.24721254355401	0.266261788214751	0.562718212206433
GO:0140566	histone reader activity	1/164	35/18639	0.0285714285714286	3.24721254355401	0.266261788214751	0.562718212206433
GO:0001221	transcription coregulator binding	2/164	115/18639	0.0173913043478261	1.97656415694592	0.268622217408763	0.564795431474836
GO:0009055	electron transfer activity	2/164	116/18639	0.0172413793103448	1.95952481076535	0.271883198247768	0.56547644893521
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/164	36/18639	0.0277777777777778	3.15701219512195	0.272729916936143	0.56547644893521
GO:0005543	phospholipid binding	6/164	497/18639	0.0120724346076459	1.37206163812141	0.273600234527079	0.56547644893521
GO:0019208	phosphatase regulator activity	2/164	117/18639	0.0170940170940171	1.94277673545966	0.275143767282015	0.56547644893521
GO:0022853	active monoatomic ion transmembrane transporter activity	2/164	118/18639	0.0169491525423729	1.92631252583712	0.278403680727836	0.56547644893521
GO:0019213	deacetylase activity	1/164	37/18639	0.027027027027027	3.07168754119974	0.279141371734964	0.56547644893521
GO:0042805	actinin binding	1/164	37/18639	0.027027027027027	3.07168754119974	0.279141371734964	0.56547644893521
GO:0008094	ATP-dependent activity, acting on DNA	3/164	210/18639	0.0142857142857143	1.623606271777	0.28176001702295	0.56547644893521
GO:0005109	frizzled binding	1/164	38/18639	0.0263157894736842	2.99085365853659	0.285496646169728	0.56547644893521
GO:0005501	retinoid binding	1/164	38/18639	0.0263157894736842	2.99085365853659	0.285496646169728	0.56547644893521
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/164	38/18639	0.0263157894736842	2.99085365853659	0.285496646169728	0.56547644893521
GO:0019840	isoprenoid binding	1/164	38/18639	0.0263157894736842	2.99085365853659	0.285496646169728	0.56547644893521
GO:0004540	RNA nuclease activity	2/164	121/18639	0.0165289256198347	1.87855271114695	0.288177113410696	0.568041425473007
GO:0004532	RNA exonuclease activity	1/164	40/18639	0.025	2.84131097560976	0.298040606858028	0.576399286848073
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/164	40/18639	0.025	2.84131097560976	0.298040606858028	0.576399286848073
GO:0030331	nuclear estrogen receptor binding	1/164	40/18639	0.025	2.84131097560976	0.298040606858028	0.576399286848073
GO:0071855	neuropeptide receptor binding	1/164	40/18639	0.025	2.84131097560976	0.298040606858028	0.576399286848073
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	1/164	41/18639	0.024390243902439	2.77201070791196	0.304230259015418	0.580160028820099
GO:0008137	NADH dehydrogenase (ubiquinone) activity	1/164	41/18639	0.024390243902439	2.77201070791196	0.304230259015418	0.580160028820099
GO:0016877	ligase activity, forming carbon-sulfur bonds	1/164	41/18639	0.024390243902439	2.77201070791196	0.304230259015418	0.580160028820099
GO:0008307	structural constituent of muscle	1/164	42/18639	0.0238095238095238	2.70601045296167	0.31036566268901	0.581049870787644
GO:0035198	miRNA binding	1/164	42/18639	0.0238095238095238	2.70601045296167	0.31036566268901	0.581049870787644
GO:0042056	chemoattractant activity	1/164	42/18639	0.0238095238095238	2.70601045296167	0.31036566268901	0.581049870787644
GO:0051879	Hsp90 protein binding	1/164	42/18639	0.0238095238095238	2.70601045296167	0.31036566268901	0.581049870787644
GO:0005245	voltage-gated calcium channel activity	1/164	43/18639	0.0232558139534884	2.6430799773114	0.316447290441819	0.58244493570776
GO:0008375	acetylglucosaminyltransferase activity	1/164	43/18639	0.0232558139534884	2.6430799773114	0.316447290441819	0.58244493570776
GO:0061134	peptidase regulator activity	3/164	226/18639	0.0132743362831858	1.50866069501403	0.320163371398352	0.58244493570776
GO:0031072	heat shock protein binding	2/164	131/18639	0.0152671755725191	1.73515174083039	0.320619508915854	0.58244493570776
GO:0001046	core promoter sequence-specific DNA binding	1/164	44/18639	0.0227272727272727	2.58300997782705	0.322475610745516	0.58244493570776
GO:0003954	NADH dehydrogenase activity	1/164	44/18639	0.0227272727272727	2.58300997782705	0.322475610745516	0.58244493570776
GO:0030020	extracellular matrix structural constituent conferring tensile strength	1/164	44/18639	0.0227272727272727	2.58300997782705	0.322475610745516	0.58244493570776
GO:0030547	signaling receptor inhibitor activity	1/164	44/18639	0.0227272727272727	2.58300997782705	0.322475610745516	0.58244493570776
GO:0008009	chemokine activity	1/164	45/18639	0.0222222222222222	2.52560975609756	0.328451088015628	0.590454481144602
GO:0000287	magnesium ion binding	3/164	230/18639	0.0130434782608696	1.48242311770944	0.329790429712473	0.590454481144602
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/164	46/18639	0.0217391304347826	2.4707051961824	0.334374182646447	0.596058325587144
GO:0140938	histone H3 methyltransferase activity	1/164	47/18639	0.0212765957446809	2.41813700051894	0.340245351045628	0.60389867501605
GO:0140693	molecular condensate scaffold activity	1/164	48/18639	0.0208333333333333	2.36775914634146	0.346065045668505	0.611580468638306
GO:0016763	pentosyltransferase activity	1/164	49/18639	0.0204081632653061	2.31943753111	0.351833715052097	0.616460782783588
GO:0035254	glutamate receptor binding	1/164	49/18639	0.0204081632653061	2.31943753111	0.351833715052097	0.616460782783588
GO:0022843	voltage-gated monoatomic cation channel activity	2/164	143/18639	0.013986013986014	1.58954460173972	0.35905758506589	0.625714700305073
GO:0019955	cytokine binding	2/164	144/18639	0.0138888888888889	1.57850609756098	0.362227796872341	0.625714700305073
GO:0005010	insulin-like growth factor receptor activity	1/164	51/18639	0.0196078431372549	2.22847919655667	0.363219752860018	0.625714700305073
GO:0030544	Hsp70 protein binding	1/164	51/18639	0.0196078431372549	2.22847919655667	0.363219752860018	0.625714700305073
GO:0042393	histone binding	3/164	247/18639	0.0121457489878543	1.38039399624765	0.370614700741706	0.635782541021336
GO:0016860	intramolecular oxidoreductase activity	1/164	53/18639	0.0188679245283019	2.14438564196963	0.374406975673675	0.636957925419946
GO:0051018	protein kinase A binding	1/164	53/18639	0.0188679245283019	2.14438564196963	0.374406975673675	0.636957925419946
GO:0140463	chromatin-protein adaptor activity	1/164	54/18639	0.0185185185185185	2.10467479674797	0.379927112119899	0.643678165161813
GO:0098632	cell-cell adhesion mediator activity	1/164	55/18639	0.0181818181818182	2.06640798226164	0.385398834132939	0.650261407384794
GO:0003713	transcription coactivator activity	3/164	256/18639	0.01171875	1.33186451981707	0.392068615118405	0.658803820485844
GO:0008408	3'-5' exonuclease activity	1/164	58/18639	0.0172413793103448	1.95952481076535	0.40152771569352	0.664510299659292
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	1/164	58/18639	0.0172413793103448	1.95952481076535	0.40152771569352	0.664510299659292
GO:0061980	regulatory RNA binding	1/164	58/18639	0.0172413793103448	1.95952481076535	0.40152771569352	0.664510299659292
GO:0003730	mRNA 3'-UTR binding	3/164	262/18639	0.0114503816793893	1.30136380562279	0.406272762452683	0.664510299659292
GO:0004879	nuclear receptor activity	1/164	59/18639	0.0169491525423729	1.92631252583712	0.406809963937762	0.664510299659292
GO:0036002	pre-mRNA binding	1/164	59/18639	0.0169491525423729	1.92631252583712	0.406809963937762	0.664510299659292
GO:0070063	RNA polymerase binding	1/164	59/18639	0.0169491525423729	1.92631252583712	0.406809963937762	0.664510299659292
GO:0004714	transmembrane receptor protein tyrosine kinase activity	1/164	60/18639	0.0166666666666667	1.89420731707317	0.412045871683413	0.665113414922045
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/164	60/18639	0.0166666666666667	1.89420731707317	0.412045871683413	0.665113414922045
GO:0098531	ligand-modulated transcription factor activity	1/164	60/18639	0.0166666666666667	1.89420731707317	0.412045871683413	0.665113414922045
GO:0005178	integrin binding	2/164	161/18639	0.0124223602484472	1.41183154067566	0.415126804493347	0.667458783695185
GO:0016836	hydro-lyase activity	1/164	61/18639	0.0163934426229508	1.86315473810476	0.417235842997474	0.668229279800641
GO:0005096	GTPase activator activity	3/164	271/18639	0.011070110701107	1.25814508145081	0.427393651582784	0.678038880397922
GO:0005507	copper ion binding	1/164	63/18639	0.0158730158730159	1.80400696864111	0.427479575120418	0.678038880397922
GO:0140297	DNA-binding transcription factor binding	5/164	488/18639	0.0102459016393443	1.16447171131547	0.429340909783708	0.678038880397922
GO:0015399	primary active transmembrane transporter activity	2/164	166/18639	0.0120481927710843	1.36930649426976	0.430277794065574	0.678038880397922
GO:0016791	phosphatase activity	3/164	273/18639	0.010989010989011	1.24892790136693	0.432052946554853	0.678038880397922
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	2/164	167/18639	0.0119760479041916	1.36110705418431	0.433283382107941	0.678038880397922
GO:0019843	rRNA binding	1/164	65/18639	0.0153846153846154	1.7484990619137	0.437544323349435	0.679519593080561
GO:0160215	deacylase activity	1/164	65/18639	0.0153846153846154	1.7484990619137	0.437544323349435	0.679519593080561
GO:0140098	catalytic activity, acting on RNA	4/164	387/18639	0.0103359173126615	1.1747022121384	0.444062325728103	0.68405544448121
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1/164	67/18639	0.0149253731343284	1.69630506006553	0.447433196133256	0.68405544448121
GO:0042054	histone methyltransferase activity	1/164	67/18639	0.0149253731343284	1.69630506006553	0.447433196133256	0.68405544448121
GO:0008201	heparin binding	2/164	172/18639	0.0116279069767442	1.3215399886557	0.448183473871591	0.68405544448121
GO:0005244	voltage-gated monoatomic ion channel activity	2/164	173/18639	0.0115606936416185	1.3139010291837	0.451137356526021	0.68405544448121
GO:0030145	manganese ion binding	1/164	68/18639	0.0147058823529412	1.6713593974175	0.452312635926178	0.68405544448121
GO:0031267	small GTPase binding	3/164	283/18639	0.0106007067137809	1.20479617340343	0.455137617113919	0.68405544448121
GO:0003735	structural constituent of ribosome	2/164	175/18639	0.0114285714285714	1.2988850174216	0.457018376132288	0.68405544448121
GO:0022832	voltage-gated channel activity	2/164	175/18639	0.0114285714285714	1.2988850174216	0.457018376132288	0.68405544448121
GO:0016279	protein-lysine N-methyltransferase activity	1/164	69/18639	0.0144927536231884	1.64713679745493	0.457149248263053	0.68405544448121
GO:0016278	lysine N-methyltransferase activity	1/164	70/18639	0.0142857142857143	1.623606271777	0.461943406759814	0.686220278157695
GO:0097110	scaffold protein binding	1/164	70/18639	0.0142857142857143	1.623606271777	0.461943406759814	0.686220278157695
GO:0140299	molecular sensor activity	1/164	71/18639	0.0140845070422535	1.60073857780831	0.466695481793009	0.690776705903009
GO:0042379	chemokine receptor binding	1/164	72/18639	0.0138888888888889	1.57850609756098	0.471405840527711	0.695238829555257
GO:0004521	RNA endonuclease activity	1/164	73/18639	0.0136986301369863	1.55688272636151	0.476074846945196	0.697109597312608
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/164	73/18639	0.0136986301369863	1.55688272636151	0.476074846945196	0.697109597312608
GO:0061135	endopeptidase regulator activity	2/164	184/18639	0.0108695652173913	1.2353525980912	0.483028198544929	0.704774239869825
GO:0015078	proton transmembrane transporter activity	2/164	185/18639	0.0108108108108108	1.22867501647989	0.485871002962173	0.706408195796068
GO:0098631	cell adhesion mediator activity	1/164	76/18639	0.0131578947368421	1.49542682926829	0.489837344924696	0.709658344237191
GO:0019199	transmembrane receptor protein kinase activity	1/164	78/18639	0.0128205128205128	1.45708255159475	0.498812114190667	0.716418732406723
GO:0004857	enzyme inhibitor activity	4/164	416/18639	0.00961538461538462	1.09281191369606	0.499692760967233	0.716418732406723
GO:0016887	ATP hydrolysis activity	4/164	417/18639	0.00959232613908873	1.09019126162485	0.501570856064286	0.716418732406723
GO:0016835	carbon-oxygen lyase activity	1/164	79/18639	0.0126582278481013	1.43863846866317	0.503240475446673	0.716418732406723
GO:0046332	SMAD binding	1/164	79/18639	0.0126582278481013	1.43863846866317	0.503240475446673	0.716418732406723
GO:0015101	organic cation transmembrane transporter activity	1/164	81/18639	0.0123456790123457	1.40311653116531	0.511980863480184	0.723835013885777
GO:0030971	receptor tyrosine kinase binding	1/164	81/18639	0.0123456790123457	1.40311653116531	0.511980863480184	0.723835013885777
GO:0005254	chloride channel activity	1/164	83/18639	0.0120481927710843	1.36930649426976	0.520568387369716	0.728440405534414
GO:0008135	translation factor activity, RNA binding	1/164	83/18639	0.0120481927710843	1.36930649426976	0.520568387369716	0.728440405534414
GO:0030165	PDZ domain binding	1/164	83/18639	0.0120481927710843	1.36930649426976	0.520568387369716	0.728440405534414
GO:0004527	exonuclease activity	1/164	84/18639	0.0119047619047619	1.35300522648084	0.524805657496433	0.728775608264969
GO:0180051	translation factor activity	1/164	84/18639	0.0119047619047619	1.35300522648084	0.524805657496433	0.728775608264969
GO:0051020	GTPase binding	3/164	315/18639	0.00952380952380952	1.08240418118467	0.526140439137636	0.728775608264969
GO:0022836	gated channel activity	3/164	318/18639	0.00943396226415094	1.07219282098481	0.532539405649611	0.735155408472527
GO:0008168	methyltransferase activity	2/164	204/18639	0.00980392156862745	1.11423959827834	0.538001638388019	0.739893848433861
GO:0004197	cysteine-type endopeptidase activity	1/164	88/18639	0.0113636363636364	1.29150498891353	0.541385742756484	0.739893848433861
GO:0016651	oxidoreductase activity, acting on NAD(P)H	1/164	88/18639	0.0113636363636364	1.29150498891353	0.541385742756484	0.739893848433861
GO:0003727	single-stranded RNA binding	1/164	89/18639	0.0112359550561798	1.27699369690326	0.545440119242276	0.742958301957918
GO:0004518	nuclease activity	2/164	209/18639	0.00956937799043062	1.08758314855876	0.551107618169726	0.748192461753602
GO:0005216	monoatomic ion channel activity	4/164	448/18639	0.00892857142857143	1.01475391986063	0.558172581681718	0.755283031318496
GO:0016741	transferase activity, transferring one-carbon groups	2/164	215/18639	0.00930232558139535	1.05723199092456	0.566489325943323	0.761099328047572
GO:0004867	serine-type endopeptidase inhibitor activity	1/164	95/18639	0.0105263157894737	1.19634146341463	0.56902902697033	0.761099328047572
GO:0008276	protein methyltransferase activity	1/164	95/18639	0.0105263157894737	1.19634146341463	0.56902902697033	0.761099328047572
GO:0140097	catalytic activity, acting on DNA	3/164	336/18639	0.00892857142857143	1.01475391986063	0.569896326123426	0.761099328047572
GO:0005261	monoatomic cation channel activity	3/164	341/18639	0.00879765395894428	0.999874830126601	0.579945451165929	0.767577017829479
GO:0005249	voltage-gated potassium channel activity	1/164	98/18639	0.0102040816326531	1.159718765555	0.580363111041801	0.767577017829479
GO:0008170	N-methyltransferase activity	1/164	98/18639	0.0102040816326531	1.159718765555	0.580363111041801	0.767577017829479
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	3/164	349/18639	0.00859598853868195	0.976955063246908	0.595716596594678	0.785349854031569
GO:0005253	monoatomic anion channel activity	1/164	103/18639	0.00970873786407767	1.10342173810088	0.598598607196561	0.786619964585224
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	2/164	229/18639	0.00873362445414847	0.992597720737033	0.600899007209966	0.78712010529101
GO:0061630	ubiquitin protein ligase activity	3/164	353/18639	0.0084985835694051	0.965884750915498	0.603458042445923	0.78795262348621
GO:0141003	histone H2AX kinase activity	3/164	354/18639	0.00847457627118644	0.963156262918561	0.605378235117454	0.78795262348621
GO:0000149	SNARE binding	1/164	106/18639	0.00943396226415094	1.07219282098481	0.609159558247267	0.789937735372137
GO:0140996	histone H3 kinase activity	3/164	357/18639	0.00840336134453781	0.955062512810002	0.61110220561116	0.789937735372137
GO:0005125	cytokine activity	2/164	234/18639	0.00854700854700855	0.971388367729831	0.612683414264243	0.789937735372137
GO:0035173	histone kinase activity	3/164	360/18639	0.00833333333333333	0.947103658536585	0.616771022976623	0.792715107900988
GO:0004620	phospholipase activity	1/164	109/18639	0.00917431192660551	1.04268292682927	0.619444298434257	0.793022014639323
GO:0042578	phosphoric ester hydrolase activity	3/164	363/18639	0.00826446280991736	0.939276355573473	0.622384403400774	0.793022014639323
GO:0004222	metalloendopeptidase activity	1/164	110/18639	0.00909090909090909	1.03320399113082	0.622812411497224	0.793022014639323
GO:0030695	GTPase regulator activity	4/164	489/18639	0.0081799591002045	0.929672302857998	0.627451591628961	0.7960137417673
GO:0060589	nucleoside-triphosphatase regulator activity	4/164	490/18639	0.00816326530612245	0.927775012444002	0.629053627410443	0.7960137417673
GO:0005539	glycosaminoglycan binding	2/164	242/18639	0.00826446280991736	0.939276355573473	0.630986502620421	0.7960137417673
GO:0061659	ubiquitin-like protein ligase activity	3/164	372/18639	0.00806451612903226	0.91655192761605	0.638889555902342	0.801460582441856
GO:0017124	SH3 domain binding	1/164	115/18639	0.00869565217391304	0.988282078472959	0.63921368404509	0.801460582441856
GO:1990782	protein tyrosine kinase binding	1/164	117/18639	0.00854700854700855	0.971388367729831	0.645573931966083	0.806967414957604
GO:0015108	chloride transmembrane transporter activity	1/164	121/18639	0.00826446280991736	0.939276355573473	0.65796201253052	0.819952659992441
GO:0005267	potassium channel activity	1/164	124/18639	0.00806451612903226	0.91655192761605	0.666969770621044	0.828659411983722
GO:0004519	endonuclease activity	1/164	127/18639	0.0078740157480315	0.894901094680238	0.675741713006435	0.830345489393916
GO:0042826	histone deacetylase binding	1/164	127/18639	0.0078740157480315	0.894901094680238	0.675741713006435	0.830345489393916
GO:0031490	chromatin DNA binding	1/164	128/18639	0.0078125	0.887909679878049	0.678614355566231	0.830345489393916
GO:0016298	lipase activity	1/164	130/18639	0.00769230769230769	0.874249530956848	0.684283976261607	0.830345489393916
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1/164	130/18639	0.00769230769230769	0.874249530956848	0.684283976261607	0.830345489393916
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	2/164	268/18639	0.00746268656716418	0.848152530032763	0.685840964674941	0.830345489393916
GO:0005262	calcium channel activity	1/164	131/18639	0.00763358778625954	0.867575870415193	0.68708139524119	0.830345489393916
GO:0005179	hormone activity	1/164	132/18639	0.00757575757575758	0.86100332594235	0.689854177345169	0.830345489393916
GO:0004175	endopeptidase activity	3/164	405/18639	0.00740740740740741	0.841869918699187	0.695062034728058	0.830345489393916
GO:0051087	protein-folding chaperone binding	1/164	134/18639	0.00746268656716418	0.848152530032763	0.695326691680229	0.830345489393916
GO:1901681	sulfur compound binding	2/164	275/18639	0.00727272727272727	0.826563192904656	0.699426417750292	0.830345489393916
GO:0019838	growth factor binding	1/164	136/18639	0.00735294117647059	0.835679698708752	0.700703222109855	0.830345489393916
GO:0044325	transmembrane transporter binding	1/164	136/18639	0.00735294117647059	0.835679698708752	0.700703222109855	0.830345489393916
GO:0099094	ligand-gated monoatomic cation channel activity	1/164	136/18639	0.00735294117647059	0.835679698708752	0.700703222109855	0.830345489393916
GO:0016922	nuclear receptor binding	1/164	137/18639	0.0072992700729927	0.829579846893359	0.703356017417318	0.830345489393916
GO:0001217	DNA-binding transcription repressor activity	2/164	278/18639	0.00719424460431655	0.817643446218635	0.705099098707901	0.830345489393916
GO:0030295	protein kinase activator activity	1/164	139/18639	0.00719424460431655	0.817643446218635	0.708591700420145	0.830345489393916
GO:0070851	growth factor receptor binding	1/164	139/18639	0.00719424460431655	0.817643446218635	0.708591700420145	0.830345489393916
GO:0140101	catalytic activity, acting on a tRNA	1/164	139/18639	0.00719424460431655	0.817643446218635	0.708591700420145	0.830345489393916
GO:0030246	carbohydrate binding	2/164	280/18639	0.00714285714285714	0.811803135888502	0.70883151533627	0.830345489393916
GO:0019903	protein phosphatase binding	1/164	144/18639	0.00694444444444444	0.789253048780488	0.72128253962677	0.842523764236398
GO:0015293	symporter activity	1/164	146/18639	0.00684931506849315	0.778441363180755	0.726203678158513	0.845862238764177
GO:0015085	calcium ion transmembrane transporter activity	1/164	147/18639	0.00680272108843537	0.773145843703335	0.728631764287427	0.846286185149703
GO:0019209	kinase activator activity	1/164	148/18639	0.00675675675675676	0.767921885299934	0.731038447753621	0.846682947963234
GO:0008509	monoatomic anion transmembrane transporter activity	1/164	149/18639	0.00671140939597315	0.762768047143559	0.733423916066228	0.847052973484939
GO:0019842	vitamin binding	1/164	150/18639	0.00666666666666667	0.757682926829268	0.73578835510166	0.847396701100226
GO:0031625	ubiquitin protein ligase binding	2/164	302/18639	0.00662251655629139	0.752665159101922	0.747348201322261	0.858299054739851
GO:0015079	potassium ion transmembrane transporter activity	1/164	160/18639	0.00625	0.710327743902439	0.758315888553692	0.866080378708107
GO:0004842	ubiquitin-protein transferase activity	3/164	449/18639	0.0066815144766147	0.759370416644033	0.759425100284776	0.866080378708107
GO:0004866	endopeptidase inhibitor activity	1/164	161/18639	0.0062111801242236	0.705915770337828	0.760460820329069	0.866080378708107
GO:0015103	inorganic anion transmembrane transporter activity	1/164	165/18639	0.00606060606060606	0.68880266075388	0.768852988263	0.871960171084614
GO:0022804	active transmembrane transporter activity	3/164	457/18639	0.00656455142231947	0.746077280247638	0.769877029103977	0.871960171084614
GO:0016874	ligase activity	1/164	167/18639	0.00598802395209581	0.680553527092157	0.772938824058785	0.872103076474045
GO:0005201	extracellular matrix structural constituent	1/164	168/18639	0.00595238095238095	0.676502613240418	0.774954741818332	0.872103076474045
GO:0030414	peptidase inhibitor activity	1/164	169/18639	0.00591715976331361	0.672499639197575	0.776952869821244	0.872103076474045
GO:0044389	ubiquitin-like protein ligase binding	2/164	322/18639	0.0062111801242236	0.705915770337828	0.77851152680366	0.872103076474045
GO:0004252	serine-type endopeptidase activity	1/164	176/18639	0.00568181818181818	0.645752494456763	0.790454589570139	0.883069160010237
GO:0019787	ubiquitin-like protein transferase activity	3/164	479/18639	0.00626304801670146	0.711810682824991	0.79673196355234	0.886041318243967
GO:0016853	isomerase activity	1/164	180/18639	0.00555555555555556	0.63140243902439	0.797801821980175	0.886041318243967
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	1/164	181/18639	0.00552486187845304	0.627914027759062	0.799598262805531	0.886041318243967
GO:0008237	metallopeptidase activity	1/164	184/18639	0.00543478260869565	0.617676299045599	0.804892956337869	0.889418291181409
GO:0015276	ligand-gated monoatomic ion channel activity	1/164	186/18639	0.00537634408602151	0.6110346184107	0.808345271871202	0.889418291181409
GO:0008234	cysteine-type peptidase activity	1/164	187/18639	0.0053475935828877	0.607767053606365	0.810048592491866	0.889418291181409
GO:0022834	ligand-gated channel activity	1/164	188/18639	0.00531914893617021	0.604534250129735	0.811736866436768	0.889418291181409
GO:0019902	phosphatase binding	1/164	190/18639	0.00526315789473684	0.598170731707317	0.815068801586426	0.889418291181409
GO:0016755	aminoacyltransferase activity	3/164	496/18639	0.00604838709677419	0.687413945712038	0.815661652400512	0.889418291181409
GO:0008236	serine-type peptidase activity	1/164	194/18639	0.00515463917525773	0.585837314558713	0.821557847934154	0.893471399610087
GO:0017171	serine hydrolase activity	1/164	198/18639	0.00505050505050505	0.5740022172949	0.827820540105865	0.896464424792181
GO:0106310	protein serine kinase activity	2/164	361/18639	0.00554016620498615	0.629653401797176	0.829762598159145	0.896464424792181
GO:0016829	lyase activity	1/164	200/18639	0.005	0.568262195121951	0.830869466880558	0.896464424792181
GO:0005085	guanyl-nucleotide exchange factor activity	1/164	230/18639	0.00434782608695652	0.494141039236479	0.870660667670106	0.901891311912055
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	1/164	243/18639	0.00411522633744856	0.467705510388437	0.884869132669654	0.901891311912055
GO:0004676	3-phosphoinositide-dependent protein kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:0004711	ribosomal protein S6 kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:0035175	histone H3S10 kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:0035979	histone H2AXS139 kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:0044022	histone H3S28 kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:0044023	histone H4S1 kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:0044024	histone H2AS1 kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:0044025	histone H2BS14 kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:0072354	histone H3T3 kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:0072371	histone H2AS121 kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:0072518	Rho-dependent protein serine/threonine kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:0140823	histone H2BS36 kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:0140855	histone H3S57 kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:0140995	histone H2A kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:0140997	histone H4 kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:0140998	histone H2B kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:1990244	histone H2AT120 kinase activity	1/164	245/18639	0.00408163265306122	0.463887506222001	0.886912816834257	0.901891311912055
GO:0004677	DNA-dependent protein kinase activity	1/164	246/18639	0.0040650406504065	0.462001784651993	0.887921096601528	0.901891311912055
GO:0140857	histone H3T45 kinase activity	1/164	246/18639	0.0040650406504065	0.462001784651993	0.887921096601528	0.901891311912055
GO:0035402	histone H3T11 kinase activity	1/164	247/18639	0.00404858299595142	0.460131332082552	0.888920440925855	0.901891311912055
GO:0035403	histone H3T6 kinase activity	1/164	247/18639	0.00404858299595142	0.460131332082552	0.888920440925855	0.901891311912055
GO:0004679	AMP-activated protein kinase activity	1/164	248/18639	0.00403225806451613	0.458275963808025	0.889910928512206	0.901891311912055
GO:0042277	peptide binding	1/164	249/18639	0.00401606425702811	0.456435498089921	0.890892637376542	0.901891311912055
GO:0004674	protein serine/threonine kinase activity	2/164	433/18639	0.0046189376443418	0.524953528981017	0.897251600821169	0.906091518070639
GO:0046873	metal ion transmembrane transporter activity	2/164	450/18639	0.00444444444444444	0.505121951219512	0.909080993931047	0.915781836638155
GO:0015291	secondary active transmembrane transporter activity	1/164	287/18639	0.00348432055749129	0.396001529701708	0.922398402428119	0.926919963224335
GO:0045296	cadherin binding	1/164	334/18639	0.0029940119760479	0.340276763546079	0.949135800168037	0.951456425596321
GO:0046982	protein heterodimerization activity	1/164	369/18639	0.002710027100271	0.308001189767995	0.962890372873901	0.962890372873901