ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003712 transcription coregulator activity 233/5291 495/18639 0.470707070707071 1.65819487637669 3.36527102119563e-19 4.54648114963529e-16 GO:0140297 DNA-binding transcription factor binding 227/5291 488/18639 0.465163934426229 1.63866765711028 5.68190075891579e-18 3.83812396264761e-15 GO:0019787 ubiquitin-like protein transferase activity 222/5291 479/18639 0.463465553235908 1.63268464312306 2.24158061264735e-17 1.00945846922886e-14 GO:0016755 aminoacyltransferase activity 225/5291 496/18639 0.453629032258065 1.59803279762957 2.82501088727577e-16 9.54147427177393e-14 GO:0004842 ubiquitin-protein transferase activity 205/5291 449/18639 0.456570155902004 1.60839371307077 2.67851093475299e-15 7.23733654570257e-13 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 164/5291 349/18639 0.469914040114613 1.6554012084098 8.05115991403567e-14 1.8128528406437e-11 GO:0003714 transcription corepressor activity 106/5291 204/18639 0.519607843137255 1.83046127163774 9.28979143611158e-13 1.79292974716954e-10 GO:0004674 protein serine/threonine kinase activity 189/5291 433/18639 0.4364896073903 1.5376544683704 5.19963973338841e-12 8.78089159975967e-10 GO:0106310 protein serine kinase activity 161/5291 361/18639 0.445983379501385 1.57109888688836 2.6138704787212e-11 3.92371001861371e-09 GO:0060589 nucleoside-triphosphatase regulator activity 204/5291 490/18639 0.416326530612245 1.46662449519592 1.35371147079333e-10 1.82886419704178e-08 GO:0030695 GTPase regulator activity 203/5291 489/18639 0.415132924335378 1.46241968941355 2.02213911865271e-10 2.48355449936347e-08 GO:0061659 ubiquitin-like protein ligase activity 161/5291 372/18639 0.432795698924731 1.52464166173844 4.21235193583199e-10 4.55735261163041e-08 GO:0031267 small GTPase binding 129/5291 283/18639 0.45583038869258 1.60578767999263 4.38531339387086e-10 4.55735261163041e-08 GO:0044389 ubiquitin-like protein ligase binding 141/5291 322/18639 0.437888198757764 1.54258139040748 1.99499313419335e-09 1.92516837449658e-07 GO:0003713 transcription coactivator activity 117/5291 256/18639 0.45703125 1.61001804361179 2.31178150243594e-09 2.08214453986064e-07 GO:0051020 GTPase binding 138/5291 315/18639 0.438095238095238 1.54331074331074 2.84507984308563e-09 2.40231429250543e-07 GO:0031625 ubiquitin protein ligase binding 133/5291 302/18639 0.440397350993377 1.55142056797686 3.66835824507688e-09 2.91526587594051e-07 GO:0061630 ubiquitin protein ligase activity 150/5291 353/18639 0.424929178470255 1.49692968389852 7.43335921386304e-09 5.28751338391422e-07 GO:0046332 SMAD binding 47/5291 79/18639 0.594936708860759 2.09582788063801 7.43617722386159e-09 5.28751338391422e-07 GO:0016922 nuclear receptor binding 70/5291 137/18639 0.510948905109489 1.79995778535925 1.60710392315841e-08 1.08559870009351e-06 GO:0032182 ubiquitin-like protein binding 62/5291 120/18639 0.516666666666667 1.82010017010017 6.12595035800145e-08 3.9410280636476e-06 GO:0005096 GTPase activator activity 116/5291 271/18639 0.428044280442804 1.50790348576326 2.27871770497646e-07 1.39933982701055e-05 GO:0001221 transcription coregulator binding 58/5291 115/18639 0.504347826086956 1.77670367235585 4.67866155595618e-07 2.74820511395513e-05 GO:0035173 histone kinase activity 145/5291 360/18639 0.402777777777778 1.41889529389529 6.5541740174271e-07 3.68945379064334e-05 GO:0004679 AMP-activated protein kinase activity 106/5291 248/18639 0.42741935483871 1.50570201376653 8.07004676384413e-07 4.22388382447333e-05 GO:0140030 modification-dependent protein binding 79/5291 173/18639 0.456647398843931 1.60866582253865 9.08544378925917e-07 4.22388382447333e-05 GO:0140857 histone H3T45 kinase activity 105/5291 246/18639 0.426829268292683 1.50362327191595 9.81723197950634e-07 4.22388382447333e-05 GO:0019207 kinase regulator activity 119/5291 287/18639 0.414634146341463 1.46066260700407 1.17116225117293e-06 4.22388382447333e-05 GO:0016779 nucleotidyltransferase activity 65/5291 136/18639 0.477941176470588 1.68367899985547 1.17304262268937e-06 4.22388382447333e-05 GO:0140098 catalytic activity, acting on RNA 153/5291 387/18639 0.395348837209302 1.39272481132946 1.2092412213396e-06 4.22388382447333e-05 GO:0035403 histone H3T6 kinase activity 105/5291 247/18639 0.425101214574899 1.49753572830496 1.23527684785485e-06 4.22388382447333e-05 GO:0004676 3-phosphoinositide-dependent protein kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:0004711 ribosomal protein S6 kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:0035175 histone H3S10 kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:0035979 histone H2AXS139 kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:0044022 histone H3S28 kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:0044023 histone H4S1 kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:0044024 histone H2AS1 kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:0044025 histone H2BS14 kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:0072354 histone H3T3 kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:0072371 histone H2AS121 kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:0072518 Rho-dependent protein serine/threonine kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:0140823 histone H2BS36 kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:0140855 histone H3S57 kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:0140995 histone H2A kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:0140997 histone H4 kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:0140998 histone H2B kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:1990244 histone H2AT120 kinase activity 104/5291 245/18639 0.424489795918367 1.49538183823898 1.50071372002013e-06 4.22388382447333e-05 GO:0001222 transcription corepressor binding 30/5291 49/18639 0.612244897959184 2.1568007282293 1.64696086848797e-06 4.54090639454541e-05 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 103/5291 243/18639 0.423868312757202 1.49319249319249 1.82256043391007e-06 4.92455829242501e-05 GO:0004677 DNA-dependent protein kinase activity 104/5291 246/18639 0.422764227642276 1.48930305027866 1.88081945449355e-06 4.96331613319344e-05 GO:0141003 histone H2AX kinase activity 141/5291 354/18639 0.398305084745763 1.40313900483392 1.93364162344219e-06 4.96331613319344e-05 GO:0140996 histone H3 kinase activity 142/5291 357/18639 0.397759103641457 1.40121563650975 1.94711883833644e-06 4.96331613319344e-05 GO:0035402 histone H3T11 kinase activity 104/5291 247/18639 0.421052631578947 1.48327348327348 2.35030498659445e-06 5.88011488312798e-05 GO:0019887 protein kinase regulator activity 106/5291 255/18639 0.415686274509804 1.46436901731019 3.8201990408602e-06 9.38379800764024e-05 GO:0019209 kinase activator activity 68/5291 148/18639 0.459459459459459 1.61857207803154 3.89358938695872e-06 9.39328439603791e-05 GO:0005085 guanyl-nucleotide exchange factor activity 97/5291 230/18639 0.421739130434783 1.48569186395273 4.65139486829732e-06 0.000110246218720521 GO:0043539 protein serine/threonine kinase activator activity 39/5291 73/18639 0.534246575342466 1.88203022449598 5.83352268654564e-06 0.000135880847405572 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 20/5291 29/18639 0.689655172413793 2.42949967087898 6.73958990942558e-06 0.000151753099460566 GO:0097472 cyclin-dependent protein kinase activity 20/5291 29/18639 0.689655172413793 2.42949967087898 6.73958990942558e-06 0.000151753099460566 GO:0003756 protein disulfide isomerase activity 15/5291 19/18639 0.789473684210526 2.78113778113778 6.98265854466698e-06 0.000152154382158792 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 15/5291 19/18639 0.789473684210526 2.78113778113778 6.98265854466698e-06 0.000152154382158792 GO:0003727 single-stranded RNA binding 45/5291 89/18639 0.50561797752809 1.78117812949274 8.0092818517889e-06 0.000171754599710584 GO:0070063 RNA polymerase binding 33/5291 59/18639 0.559322033898305 1.97036541104338 8.26799163705826e-06 0.000174532135963527 GO:0043130 ubiquitin binding 49/5291 100/18639 0.49 1.72615951615952 9.91300996098674e-06 0.000206038099342971 GO:0043021 ribonucleoprotein complex binding 77/5291 177/18639 0.435028248587571 1.53250643081152 1.14508126007773e-05 0.000234394663994699 GO:0016791 phosphatase activity 110/5291 273/18639 0.402930402930403 1.4194329578945 1.368374501307e-05 0.000275921485263547 GO:0030295 protein kinase activator activity 63/5291 139/18639 0.453237410071942 1.59665320096975 1.48451336053196e-05 0.000294937875011571 GO:0000287 magnesium ion binding 95/5291 230/18639 0.41304347826087 1.45505904201556 1.61133115882454e-05 0.000315493970372746 GO:0005160 transforming growth factor beta receptor binding 18/5291 26/18639 0.692307692307692 2.43884390038236 1.82075321979931e-05 0.000351405371421268 GO:0140416 transcription regulator inhibitor activity 21/5291 33/18639 0.636363636363636 2.24176560540197 2.63031086966413e-05 0.000500499997875527 GO:0140537 transcription regulator activator activity 10/5291 11/18639 0.909090909090909 3.20252229343138 2.75720909061685e-05 0.00051735965019769 GO:0019902 phosphatase binding 80/5291 190/18639 0.421052631578947 1.48327348327348 3.26238425203496e-05 0.000603764537602635 GO:0031072 heat shock protein binding 59/5291 131/18639 0.450381679389313 1.58659310567708 3.4323319304411e-05 0.000626632491625125 GO:0005525 GTP binding 143/5291 378/18639 0.378306878306878 1.33268983268983 3.84049015529397e-05 0.000691800293306954 GO:0001098 basal transcription machinery binding 32/5291 60/18639 0.533333333333333 1.87881307881308 4.11524345425344e-05 0.000722038169700831 GO:0001099 basal RNA polymerase II transcription machinery binding 32/5291 60/18639 0.533333333333333 1.87881307881308 4.11524345425344e-05 0.000722038169700831 GO:0000993 RNA polymerase II complex binding 22/5291 36/18639 0.611111111111111 2.15280665280665 4.22375077401353e-05 0.000731575294319522 GO:0004721 phosphoprotein phosphatase activity 74/5291 175/18639 0.422857142857143 1.48963036963037 5.33665162299777e-05 0.000912634980084809 GO:0003724 RNA helicase activity 38/5291 77/18639 0.493506493506494 1.73851210214847 7.81753664728683e-05 0.00132018650131056 GO:0141052 histone H3 demethylase activity 18/5291 28/18639 0.642857142857143 2.26464076464076 8.24552332921096e-05 0.00137527185404494 GO:0001217 DNA-binding transcription repressor activity 108/5291 278/18639 0.388489208633094 1.3685598865455 9.71281872548887e-05 0.00160024610952871 GO:0019783 ubiquitin-like protein peptidase activity 56/5291 127/18639 0.440944881889764 1.55334939586908 0.000109080269717376 0.00177551137817078 GO:0140104 molecular carrier activity 98/5291 249/18639 0.393574297188755 1.38647350695543 0.000113449380826376 0.00182464420829088 GO:0140767 enzyme-substrate adaptor activity 60/5291 139/18639 0.431654676258993 1.52062209616166 0.000131454809780392 0.00208935821192129 GO:0140597 protein carrier chaperone 77/5291 188/18639 0.409574468085106 1.44283850134914 0.000135154586932429 0.0021231842668106 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 56/5291 128/18639 0.4375 1.54121385371385 0.000140842935695241 0.00218711271407207 GO:0070411 I-SMAD binding 12/5291 16/18639 0.75 2.64208089208089 0.000147461964107481 0.00226387628987734 GO:0008186 ATP-dependent activity, acting on RNA 38/5291 79/18639 0.481012658227848 1.69449913753711 0.000155823288324437 0.00236536250029567 GO:0035091 phosphatidylinositol binding 109/5291 284/18639 0.383802816901408 1.35205078514938 0.000158499804373737 0.00237925817454355 GO:0044390 ubiquitin-like protein conjugating enzyme binding 21/5291 36/18639 0.583333333333333 2.0549518049518 0.000162470925603816 0.00241206835704127 GO:0140097 catalytic activity, acting on DNA 126/5291 336/18639 0.375 1.32104044604045 0.000166069534870199 0.00243869501749608 GO:0008094 ATP-dependent activity, acting on DNA 84/5291 210/18639 0.4 1.40910980910981 0.000179732373188109 0.00259605583892285 GO:0061650 ubiquitin-like protein conjugating enzyme activity 23/5291 41/18639 0.560975609756098 1.97619058594668 0.000180628607593448 0.00259605583892285 GO:0003924 GTPase activity 124/5291 331/18639 0.374622356495468 1.31971009312399 0.000195455716156237 0.00277958602660081 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 103/5291 268/18639 0.384328358208955 1.35390214867827 0.000222767965043734 0.00310856792333791 GO:0017056 structural constituent of nuclear pore 16/5291 25/18639 0.64 2.25457569457569 0.000223191035206349 0.00310856792333791 GO:0019001 guanyl nucleotide binding 146/5291 400/18639 0.365 1.2858127008127 0.000229074949219104 0.00312606319590919 GO:0032561 guanyl ribonucleotide binding 146/5291 400/18639 0.365 1.2858127008127 0.000229074949219104 0.00312606319590919 GO:0016763 pentosyltransferase activity 26/5291 49/18639 0.530612244897959 1.86922729779873 0.000237088895345458 0.00318209238499117 GO:0061775 cohesin loader activity 64/5291 153/18639 0.418300653594771 1.47357888534359 0.000237891436627764 0.00318209238499117 GO:0003725 double-stranded RNA binding 36/5291 75/18639 0.48 1.69093177093177 0.00024212472273063 0.00320696569028511 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 53/5291 122/18639 0.434426229508197 1.53038565333647 0.000259610045648848 0.00337811741365176 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 15/5291 23/18639 0.652173913043478 2.29746164528773 0.000260047528512052 0.00337811741365176 GO:0043175 RNA polymerase core enzyme binding 23/5291 42/18639 0.547619047619048 1.92913842913843 0.000292523033554594 0.00360540055742723 GO:0031624 ubiquitin conjugating enzyme binding 18/5291 30/18639 0.6 2.11366471366471 0.000293555929916355 0.00360540055742723 GO:0032452 histone demethylase activity 18/5291 30/18639 0.6 2.11366471366471 0.000293555929916355 0.00360540055742723 GO:0043995 histone H4K5 acetyltransferase activity 18/5291 30/18639 0.6 2.11366471366471 0.000293555929916355 0.00360540055742723 GO:0043996 histone H4K8 acetyltransferase activity 18/5291 30/18639 0.6 2.11366471366471 0.000293555929916355 0.00360540055742723 GO:0043997 histone H4K12 acetyltransferase activity 18/5291 30/18639 0.6 2.11366471366471 0.000293555929916355 0.00360540055742723 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 172/5291 484/18639 0.355371900826446 1.25189507834136 0.000316974618089763 0.00385795233368711 GO:0051536 iron-sulfur cluster binding 36/5291 76/18639 0.473684210526316 1.66868266868267 0.000335426070513968 0.00404607697557474 GO:0061631 ubiquitin conjugating enzyme activity 20/5291 35/18639 0.571428571428571 2.01301401301401 0.000339880416570665 0.00406352604236256 GO:0001216 DNA-binding transcription activator activity 174/5291 491/18639 0.354378818737271 1.24839667405859 0.000343054071626552 0.00406549167339888 GO:0036408 histone H3K14 acetyltransferase activity 17/5291 28/18639 0.607142857142857 2.13882738882739 0.000355133689937716 0.00409571209889888 GO:0043022 ribosome binding 49/5291 112/18639 0.4375 1.54121385371385 0.000356227444906124 0.00409571209889888 GO:0015616 DNA translocase activity 63/5291 152/18639 0.414473684210526 1.46009733509734 0.000357730590429362 0.00409571209889888 GO:0140674 ATP-dependent histone chaperone activity 63/5291 152/18639 0.414473684210526 1.46009733509734 0.000357730590429362 0.00409571209889888 GO:0032451 demethylase activity 22/5291 40/18639 0.55 1.93752598752599 0.000363656062918811 0.00411423881391199 GO:0004386 helicase activity 64/5291 155/18639 0.412903225806452 1.45456496424238 0.000365439420924825 0.00411423881391199 GO:0042393 histone binding 95/5291 247/18639 0.384615384615385 1.3549132779902 0.000370331908071953 0.00413486287442321 GO:0140713 histone chaperone activity 67/5291 164/18639 0.408536585365854 1.43918227454813 0.000386162714762444 0.004276277275771 GO:0046975 histone H3K36 methyltransferase activity 10/5291 13/18639 0.769230769230769 2.7098265559804 0.00039618202602041 0.00431646707381915 GO:0140852 histone ubiquitin ligase activity 10/5291 13/18639 0.769230769230769 2.7098265559804 0.00039618202602041 0.00431646707381915 GO:0016887 ATP hydrolysis activity 150/5291 417/18639 0.359712230215827 1.26718508013472 0.000404560983103034 0.00437249510537759 GO:0140296 general transcription initiation factor binding 27/5291 53/18639 0.509433962264151 1.79462098330023 0.000430976078603562 0.0046210212872493 GO:0051540 metal cluster binding 36/5291 77/18639 0.467532467532468 1.64701146519328 0.000459414820175765 0.00488716080360204 GO:0140789 histone phosphatase activity 57/5291 136/18639 0.419117647058824 1.47645696910403 0.000476981913785971 0.00503439504316286 GO:0140457 protein demethylase activity 18/5291 31/18639 0.580645161290323 2.04548198096585 0.000514880804508808 0.0053771641605114 GO:0042578 phosphoric ester hydrolase activity 132/5291 363/18639 0.363636363636364 1.28100891737255 0.000529415058035569 0.0053771641605114 GO:0000510 H3-H4 histone complex chaperone activity 62/5291 151/18639 0.410596026490066 1.44643722127166 0.000533338266105498 0.0053771641605114 GO:0140584 chromatin extrusion motor activity 62/5291 151/18639 0.410596026490066 1.44643722127166 0.000533338266105498 0.0053771641605114 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 62/5291 151/18639 0.410596026490066 1.44643722127166 0.000533338266105498 0.0053771641605114 GO:0140849 ATP-dependent H2AZ histone chaperone activity 62/5291 151/18639 0.410596026490066 1.44643722127166 0.000533338266105498 0.0053771641605114 GO:0031593 polyubiquitin modification-dependent protein binding 29/5291 59/18639 0.491525423728814 1.73153324000782 0.000578608537737342 0.00579037136654184 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 14/5291 22/18639 0.636363636363636 2.24176560540197 0.000607297457830891 0.00598875084328127 GO:0140517 protein-RNA adaptor activity 14/5291 22/18639 0.636363636363636 2.24176560540197 0.000607297457830891 0.00598875084328127 GO:0004722 protein serine/threonine phosphatase activity 45/5291 103/18639 0.436893203883495 1.53907624781411 0.000629589359448469 0.00614228488464831 GO:0010484 histone H3 acetyltransferase activity 17/5291 29/18639 0.586206896551724 2.06507472024713 0.000631959732765444 0.00614228488464831 GO:0140034 methylation-dependent protein binding 35/5291 76/18639 0.460526315789474 1.62233037233037 0.000773326215105279 0.00746259797576594 GO:1990841 promoter-specific chromatin binding 32/5291 68/18639 0.470588235294118 1.65777624601154 0.000809030926399021 0.00775177859266012 GO:0043425 bHLH transcription factor binding 18/5291 32/18639 0.5625 1.98156066906067 0.000866082988221655 0.008125542479774 GO:0070717 poly-purine tract binding 18/5291 32/18639 0.5625 1.98156066906067 0.000866082988221655 0.008125542479774 GO:0140142 nucleocytoplasmic carrier activity 18/5291 32/18639 0.5625 1.98156066906067 0.000866082988221655 0.008125542479774 GO:0051879 Hsp90 protein binding 22/5291 42/18639 0.523809523809524 1.84526284526285 0.000886948102379013 0.00826390956078653 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 37/5291 82/18639 0.451219512195122 1.58954460173972 0.000894002993838089 0.00827258934709081 GO:0004707 MAP kinase activity 11/5291 16/18639 0.6875 2.42190748440748 0.000937178426245683 0.00855491928282377 GO:0005521 lamin binding 11/5291 16/18639 0.6875 2.42190748440748 0.000937178426245683 0.00855491928282377 GO:0035064 methylated histone binding 34/5291 74/18639 0.459459459459459 1.61857207803154 0.000960962851803922 0.00871315981736308 GO:0004705 JUN kinase activity 10/5291 14/18639 0.714285714285714 2.51626751626752 0.00103248162124217 0.00929921780198781 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 8/5291 10/18639 0.8 2.81821961821962 0.00105885813967656 0.00941129833357255 GO:0051864 histone H3K36 demethylase activity 8/5291 10/18639 0.8 2.81821961821962 0.00105885813967656 0.00941129833357255 GO:0035925 mRNA 3'-UTR AU-rich region binding 17/5291 30/18639 0.566666666666667 1.9962388962389 0.00107448778264502 0.00942618827502221 GO:0051721 protein phosphatase 2A binding 17/5291 30/18639 0.566666666666667 1.9962388962389 0.00107448778264502 0.00942618827502221 GO:1990247 N6-methyladenosine-containing RNA reader activity 9/5291 12/18639 0.75 2.64208089208089 0.00108657996739463 0.00947077119967833 GO:0030331 nuclear estrogen receptor binding 21/5291 40/18639 0.525 1.84945662445662 0.00111159182757597 0.00962667025035343 GO:0010485 histone H4 acetyltransferase activity 19/5291 35/18639 0.542857142857143 1.91236331236331 0.00112244068068942 0.00965870929688794 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 14/5291 23/18639 0.608695652173913 2.14429753560188 0.00114746401454909 0.00981154356744186 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 37/5291 83/18639 0.44578313253012 1.57039346195973 0.00117700516726285 0.0100008426476234 GO:0140658 ATP-dependent chromatin remodeler activity 63/5291 158/18639 0.39873417721519 1.40465060085313 0.00118682995285482 0.0100212954144179 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 66/5291 167/18639 0.395209580838323 1.39223424253364 0.00120874473823273 0.0101429449773442 GO:1901981 phosphatidylinositol phosphate binding 72/5291 185/18639 0.389189189189189 1.37102576021495 0.00122592332370975 0.0102235951255054 GO:0044183 protein folding chaperone 34/5291 75/18639 0.453333333333333 1.59699111699112 0.00128379797417008 0.0106405586693483 GO:0019789 SUMO transferase activity 16/5291 28/18639 0.571428571428571 2.01301401301401 0.00133181795213048 0.0109712564227334 GO:0101005 deubiquitinase activity 48/5291 115/18639 0.417391304347826 1.47037545298415 0.00142016736313193 0.0112942300675717 GO:0008276 protein methyltransferase activity 41/5291 95/18639 0.431578947368421 1.52035532035532 0.00143131104082437 0.0112942300675717 GO:0033192 calmodulin-dependent protein phosphatase activity 36/5291 81/18639 0.444444444444444 1.56567756567757 0.00145462326554957 0.0112942300675717 GO:0140791 histone H2AXS140 phosphatase activity 36/5291 81/18639 0.444444444444444 1.56567756567757 0.00145462326554957 0.0112942300675717 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 36/5291 81/18639 0.444444444444444 1.56567756567757 0.00145462326554957 0.0112942300675717 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 36/5291 81/18639 0.444444444444444 1.56567756567757 0.00145462326554957 0.0112942300675717 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 36/5291 81/18639 0.444444444444444 1.56567756567757 0.00145462326554957 0.0112942300675717 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 36/5291 81/18639 0.444444444444444 1.56567756567757 0.00145462326554957 0.0112942300675717 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 36/5291 81/18639 0.444444444444444 1.56567756567757 0.00145462326554957 0.0112942300675717 GO:1990439 MAP kinase serine/threonine phosphatase activity 36/5291 81/18639 0.444444444444444 1.56567756567757 0.00145462326554957 0.0112942300675717 GO:0051082 unfolded protein binding 50/5291 121/18639 0.413223140495868 1.45569195155972 0.00148600340084369 0.0114207327140676 GO:0008170 N-methyltransferase activity 42/5291 98/18639 0.428571428571429 1.50976050976051 0.00148782306267646 0.0114207327140676 GO:0045296 cadherin binding 120/5291 334/18639 0.359281437125749 1.2656674932124 0.00151982527578542 0.0116004742801475 GO:0070412 R-SMAD binding 15/5291 26/18639 0.576923076923077 2.0323699169853 0.00164874051787612 0.0125137552789362 GO:0140036 ubiquitin-modified protein reader activity 12/5291 19/18639 0.631578947368421 2.22491022491023 0.00166338790261993 0.0125543969633493 GO:0003689 DNA clamp loader activity 63/5291 160/18639 0.39375 1.38709246834247 0.00171249364705698 0.0128532162065221 GO:0051219 phosphoprotein binding 40/5291 93/18639 0.43010752688172 1.51517183775248 0.00175583922517204 0.0131057391889913 GO:0033549 MAP kinase phosphatase activity 36/5291 82/18639 0.439024390243902 1.54658393682784 0.00189336956514985 0.01405462792592 GO:0016741 transferase activity, transferring one-carbon groups 81/5291 215/18639 0.376744186046512 1.32718482020808 0.00191090374019556 0.0141072729672361 GO:0051087 protein-folding chaperone binding 54/5291 134/18639 0.402985074626866 1.41962555395391 0.00193888777259049 0.0142360727215748 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 28/5291 60/18639 0.466666666666667 1.64396144396144 0.00195899290284476 0.0143059427661798 GO:0032183 SUMO binding 11/5291 17/18639 0.647058823529412 2.27944233826587 0.00197450730538626 0.0143417170407357 GO:0004843 cysteine-type deubiquitinase activity 45/5291 108/18639 0.416666666666667 1.46782271782272 0.0020481198753934 0.0147968446612647 GO:0035591 signaling adaptor activity 52/5291 129/18639 0.403100775193798 1.42003314096337 0.00230643387131369 0.0165744263837489 GO:0000049 tRNA binding 35/5291 80/18639 0.4375 1.54121385371385 0.0023343789735169 0.0166864867366208 GO:0019903 protein phosphatase binding 57/5291 144/18639 0.395833333333333 1.39443158193158 0.00239945498376167 0.0170613878055895 GO:0008408 3'-5' exonuclease activity 27/5291 58/18639 0.46551724137931 1.63991227784331 0.00244547649622597 0.0172975850596926 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 9/5291 13/18639 0.692307692307692 2.43884390038236 0.00263997533548662 0.0184798273484064 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 9/5291 13/18639 0.692307692307692 2.43884390038236 0.00263997533548662 0.0184798273484064 GO:0003697 single-stranded DNA binding 49/5291 121/18639 0.40495867768595 1.42657811252853 0.00271245189259805 0.0188892912726803 GO:0008234 cysteine-type peptidase activity 71/5291 187/18639 0.379679144385027 1.3375240166684 0.00278830908022305 0.0193179772686223 GO:0051539 4 iron, 4 sulfur cluster binding 22/5291 45/18639 0.488888888888889 1.72224532224532 0.00281544635008246 0.019406469484497 GO:0005114 type II transforming growth factor beta receptor binding 8/5291 11/18639 0.727272727272727 2.56201783474511 0.00291225322889059 0.0197711261921165 GO:0032404 mismatch repair complex binding 8/5291 11/18639 0.727272727272727 2.56201783474511 0.00291225322889059 0.0197711261921165 GO:0048185 activin binding 8/5291 11/18639 0.727272727272727 2.56201783474511 0.00291225322889059 0.0197711261921165 GO:0004532 RNA exonuclease activity 20/5291 40/18639 0.5 1.76138726138726 0.00309749537481009 0.0208194838376539 GO:0140662 ATP-dependent protein folding chaperone 20/5291 40/18639 0.5 1.76138726138726 0.00309749537481009 0.0208194838376539 GO:0017018 myosin phosphatase activity 36/5291 84/18639 0.428571428571429 1.50976050976051 0.00312217835490099 0.0208814997894616 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 23/5291 48/18639 0.479166666666667 1.68799612549613 0.00316087364784647 0.0210361591046334 GO:0016278 lysine N-methyltransferase activity 31/5291 70/18639 0.442857142857143 1.56008586008586 0.00321834573769558 0.0213136524099349 GO:0140566 histone reader activity 18/5291 35/18639 0.514285714285714 1.81171261171261 0.00333380351001299 0.0219705782537929 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 14/5291 25/18639 0.56 1.97275373275373 0.00342935160906713 0.0224905535138335 GO:0008187 poly-pyrimidine tract binding 16/5291 30/18639 0.533333333333333 1.87881307881308 0.00347168949360406 0.0225492908935533 GO:0070566 adenylyltransferase activity 16/5291 30/18639 0.533333333333333 1.87881307881308 0.00347168949360406 0.0225492908935533 GO:0008168 methyltransferase activity 76/5291 204/18639 0.372549019607843 1.31240619475914 0.00361359768176737 0.0233587103735298 GO:0000400 four-way junction DNA binding 11/5291 18/18639 0.611111111111111 2.15280665280665 0.00377944395783568 0.0243144227954096 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 19/5291 38/18639 0.5 1.76138726138726 0.00390105959174565 0.0249778744476227 GO:0019208 phosphatase regulator activity 47/5291 117/18639 0.401709401709402 1.41513164590088 0.00393466080921776 0.0250741827983641 GO:0071889 14-3-3 protein binding 17/5291 33/18639 0.515151515151515 1.81476263294445 0.00420249928358003 0.0266552888831766 GO:0044013 histone H2B acetyltransferase activity 13/5291 23/18639 0.565217391304348 1.99113342591603 0.00428731772999946 0.0270661974449966 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 27/5291 60/18639 0.45 1.58524853524854 0.00440601242915852 0.0276861525199682 GO:0042826 histone deacetylase binding 50/5291 127/18639 0.393700787401575 1.38691910345454 0.00483818945115333 0.0302602261426185 GO:0140101 catalytic activity, acting on a tRNA 54/5291 139/18639 0.388489208633094 1.3685598865455 0.00486045083119779 0.0302602261426185 GO:0001223 transcription coactivator binding 21/5291 44/18639 0.477272727272727 1.68132420405148 0.00498248321759379 0.030736688707622 GO:0043014 alpha-tubulin binding 21/5291 44/18639 0.477272727272727 1.68132420405148 0.00498248321759379 0.030736688707622 GO:0016279 protein-lysine N-methyltransferase activity 30/5291 69/18639 0.434782608695652 1.53164109685849 0.00516113127654946 0.0316940379755378 GO:0070273 phosphatidylinositol-4-phosphate binding 16/5291 31/18639 0.516129032258065 1.81820620530298 0.00530388037551728 0.0324232687209224 GO:0004725 protein tyrosine phosphatase activity 40/5291 98/18639 0.408163265306122 1.43786715215287 0.00539172403618242 0.0328117980760471 GO:0061980 regulatory RNA binding 26/5291 58/18639 0.448275862068966 1.57917478607134 0.00547835147277368 0.0330648616536973 GO:0061733 protein-lysine-acetyltransferase activity 22/5291 47/18639 0.468085106382979 1.64895828725616 0.00548553359330225 0.0330648616536973 GO:0052742 phosphatidylinositol kinase activity 14/5291 26/18639 0.538461538461538 1.89687858918628 0.00550673121545663 0.0330648616536973 GO:0019003 GDP binding 32/5291 75/18639 0.426666666666667 1.50305046305046 0.0055757591959929 0.0333311976716213 GO:0004527 exonuclease activity 35/5291 84/18639 0.416666666666667 1.46782271782272 0.00607240181304282 0.0361401535216777 GO:0030332 cyclin binding 17/5291 34/18639 0.5 1.76138726138726 0.00620846736937063 0.0366272463581647 GO:0052866 phosphatidylinositol phosphate phosphatase activity 17/5291 34/18639 0.5 1.76138726138726 0.00620846736937063 0.0366272463581647 GO:0004402 histone acetyltransferase activity 20/5291 42/18639 0.476190476190476 1.67751167751168 0.00626279366505052 0.0366278538592349 GO:0035198 miRNA binding 20/5291 42/18639 0.476190476190476 1.67751167751168 0.00626279366505052 0.0366278538592349 GO:0140793 histone H2AXY142 phosphatase activity 37/5291 90/18639 0.411111111111111 1.44825174825175 0.00632717087827055 0.0368448614506186 GO:0016860 intramolecular oxidoreductase activity 24/5291 53/18639 0.452830188679245 1.59521865182243 0.00640151932295307 0.0369475969366387 GO:0034212 protein N-acetyltransferase activity 24/5291 53/18639 0.452830188679245 1.59521865182243 0.00640151932295307 0.0369475969366387 GO:0016407 acetyltransferase activity 39/5291 96/18639 0.40625 1.43112714987715 0.00652733690312045 0.0369475969366387 GO:0070410 co-SMAD binding 8/5291 12/18639 0.666666666666667 2.34851634851635 0.00656359975188252 0.0369475969366387 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 8/5291 12/18639 0.666666666666667 2.34851634851635 0.00656359975188252 0.0369475969366387 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 8/5291 12/18639 0.666666666666667 2.34851634851635 0.00656359975188252 0.0369475969366387 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 8/5291 12/18639 0.666666666666667 2.34851634851635 0.00656359975188252 0.0369475969366387 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 8/5291 12/18639 0.666666666666667 2.34851634851635 0.00656359975188252 0.0369475969366387 GO:0042800 histone H3K4 methyltransferase activity 11/5291 19/18639 0.578947368421053 2.03950103950104 0.00668902103375736 0.0374973751726398 GO:0043998 histone H2A acetyltransferase activity 13/5291 24/18639 0.541666666666667 1.90816953316953 0.00694598766757421 0.0386174046868015 GO:0140612 DNA damage sensor activity 13/5291 24/18639 0.541666666666667 1.90816953316953 0.00694598766757421 0.0386174046868015 GO:0004518 nuclease activity 76/5291 209/18639 0.363636363636364 1.28100891737255 0.0072110675739853 0.0399268536575989 GO:0032266 phosphatidylinositol-3-phosphate binding 22/5291 48/18639 0.458333333333333 1.61460498960499 0.0074525535471494 0.0410955095599952 GO:0008140 cAMP response element binding protein binding 7/5291 10/18639 0.7 2.46594216594217 0.00759309302176745 0.0415314521150115 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 7/5291 10/18639 0.7 2.46594216594217 0.00759309302176745 0.0415314521150115 GO:0003925 G protein activity 24/5291 54/18639 0.444444444444444 1.56567756567757 0.00847101209658508 0.0450571392915476 GO:0032931 histone H3K56 acetyltransferase activity 12/5291 22/18639 0.545454545454545 1.92151337605883 0.00877130098717766 0.0450571392915476 GO:0043992 histone H3K9 acetyltransferase activity 12/5291 22/18639 0.545454545454545 1.92151337605883 0.00877130098717766 0.0450571392915476 GO:0043993 histone H3K18 acetyltransferase activity 12/5291 22/18639 0.545454545454545 1.92151337605883 0.00877130098717766 0.0450571392915476 GO:0043994 histone H3K23 acetyltransferase activity 12/5291 22/18639 0.545454545454545 1.92151337605883 0.00877130098717766 0.0450571392915476 GO:0043999 histone H2AK5 acetyltransferase activity 12/5291 22/18639 0.545454545454545 1.92151337605883 0.00877130098717766 0.0450571392915476 GO:0044012 histone H2AK9 acetyltransferase activity 12/5291 22/18639 0.545454545454545 1.92151337605883 0.00877130098717766 0.0450571392915476 GO:0044014 histone H2BK5 acetyltransferase activity 12/5291 22/18639 0.545454545454545 1.92151337605883 0.00877130098717766 0.0450571392915476 GO:0044015 histone H2BK12 acetyltransferase activity 12/5291 22/18639 0.545454545454545 1.92151337605883 0.00877130098717766 0.0450571392915476 GO:0044016 histone H3K4 acetyltransferase activity 12/5291 22/18639 0.545454545454545 1.92151337605883 0.00877130098717766 0.0450571392915476 GO:0044017 histone H3K27 acetyltransferase activity 12/5291 22/18639 0.545454545454545 1.92151337605883 0.00877130098717766 0.0450571392915476 GO:0044018 histone H3K36 acetyltransferase activity 12/5291 22/18639 0.545454545454545 1.92151337605883 0.00877130098717766 0.0450571392915476 GO:0046972 histone H4K16 acetyltransferase activity 12/5291 22/18639 0.545454545454545 1.92151337605883 0.00877130098717766 0.0450571392915476 GO:0050321 tau-protein kinase activity 12/5291 22/18639 0.545454545454545 1.92151337605883 0.00877130098717766 0.0450571392915476 GO:0140035 ubiquitin-like protein reader activity 12/5291 22/18639 0.545454545454545 1.92151337605883 0.00877130098717766 0.0450571392915476 GO:0140908 histone H3K122 acetyltransferase activity 12/5291 22/18639 0.545454545454545 1.92151337605883 0.00877130098717766 0.0450571392915476 GO:0000175 3'-5'-RNA exonuclease activity 17/5291 35/18639 0.485714285714286 1.71106191106191 0.00892342768098615 0.0456649651401981 GO:0030165 PDZ domain binding 34/5291 83/18639 0.409638554216867 1.44306426234137 0.00918214610397451 0.0468116203263003 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 36/5291 89/18639 0.404494382022472 1.42494250359419 0.00943925539847841 0.0477619252559713 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 36/5291 89/18639 0.404494382022472 1.42494250359419 0.00943925539847841 0.0477619252559713 GO:0031490 chromatin DNA binding 49/5291 128/18639 0.3828125 1.34856212199962 0.0096783345528203 0.0487889178390307 GO:0019888 protein phosphatase regulator activity 42/5291 107/18639 0.392523364485981 1.38277130800495 0.00980050558684136 0.0492211265718315 GO:0000030 mannosyltransferase activity 13/5291 25/18639 0.52 1.83184275184275 0.0107556767309569 0.0536196282786817 GO:0017025 TBP-class protein binding 13/5291 25/18639 0.52 1.83184275184275 0.0107556767309569 0.0536196282786817 GO:0061608 nuclear import signal receptor activity 11/5291 20/18639 0.55 1.93752598752599 0.0110896738900833 0.0550814317114066 GO:0004860 protein kinase inhibitor activity 34/5291 84/18639 0.404761904761905 1.42588492588493 0.011296772221808 0.0559045394566398 GO:0140938 histone H3 methyltransferase activity 21/5291 47/18639 0.446808510638298 1.57400563783543 0.012424970971277 0.0612632692780847 GO:0046966 nuclear thyroid hormone receptor binding 14/5291 28/18639 0.5 1.76138726138726 0.0125968719865882 0.0615899900739028 GO:0051537 2 iron, 2 sulfur cluster binding 14/5291 28/18639 0.5 1.76138726138726 0.0125968719865882 0.0615899900739028 GO:0042054 histone methyltransferase activity 28/5291 67/18639 0.417910447761194 1.47220427817443 0.0126279994452044 0.0615899900739028 GO:0097157 pre-mRNA intronic binding 8/5291 13/18639 0.615384615384615 2.16786124478432 0.012841398818116 0.0624055028894772 GO:0008013 beta-catenin binding 41/5291 106/18639 0.386792452830189 1.36258259843166 0.0139772142503101 0.0676817793984551 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 10/5291 18/18639 0.555555555555556 1.95709695709696 0.0140387196122075 0.0677368221289011 GO:0046915 transition metal ion transmembrane transporter activity 20/5291 45/18639 0.444444444444444 1.56567756567757 0.0155062099655271 0.0745512087666444 GO:0008432 JUN kinase binding 7/5291 11/18639 0.636363636363636 2.24176560540197 0.015784562659302 0.0756203693358757 GO:0008143 poly(A) binding 13/5291 26/18639 0.5 1.76138726138726 0.0160046222464571 0.0761346642780408 GO:0050681 nuclear androgen receptor binding 13/5291 26/18639 0.5 1.76138726138726 0.0160046222464571 0.0761346642780408 GO:0035613 RNA stem-loop binding 11/5291 21/18639 0.523809523809524 1.84526284526285 0.017395093993261 0.082458849069809 GO:0005024 transforming growth factor beta receptor activity 9/5291 16/18639 0.5625 1.98156066906067 0.0177952465997631 0.0840607627841957 GO:0061791 GTPase motor activity 18/5291 40/18639 0.45 1.58524853524854 0.0183156511229578 0.0859182106497081 GO:1990606 membrane scission GTPase motor activity 18/5291 40/18639 0.45 1.58524853524854 0.0183156511229578 0.0859182106497081 GO:0098531 ligand-modulated transcription factor activity 25/5291 60/18639 0.416666666666667 1.46782271782272 0.0185502740562358 0.0867177171279399 GO:0048156 tau protein binding 19/5291 43/18639 0.441860465116279 1.55657478913293 0.0193562071431878 0.090173227070506 GO:0008080 N-acetyltransferase activity 28/5291 69/18639 0.405797101449275 1.42953169040126 0.0195001950676633 0.0905318334584643 GO:0019210 kinase inhibitor activity 35/5291 90/18639 0.388888888888889 1.36996786996787 0.0201009546700747 0.0930013347920236 GO:0030291 protein serine/threonine kinase inhibitor activity 20/5291 46/18639 0.434782608695652 1.53164109685849 0.0202614704838123 0.0934240499100016 GO:0035035 histone acetyltransferase binding 12/5291 24/18639 0.5 1.76138726138726 0.0203798505042608 0.0936502654124364 GO:1990380 K48-linked deubiquitinase activity 10/5291 19/18639 0.526315789473684 1.85409185409185 0.0222050513660409 0.101691608120411 GO:0005161 platelet-derived growth factor receptor binding 8/5291 14/18639 0.571428571428571 2.01301401301401 0.0225853118807684 0.101709187836394 GO:0008174 mRNA methyltransferase activity 8/5291 14/18639 0.571428571428571 2.01301401301401 0.0225853118807684 0.101709187836394 GO:0030983 mismatched DNA binding 8/5291 14/18639 0.571428571428571 2.01301401301401 0.0225853118807684 0.101709187836394 GO:0042813 Wnt receptor activity 8/5291 14/18639 0.571428571428571 2.01301401301401 0.0225853118807684 0.101709187836394 GO:0098847 sequence-specific single stranded DNA binding 8/5291 14/18639 0.571428571428571 2.01301401301401 0.0225853118807684 0.101709187836394 GO:0008266 poly(U) RNA binding 13/5291 27/18639 0.481481481481481 1.6961506961507 0.022988458043554 0.103180753544324 GO:0000149 SNARE binding 40/5291 106/18639 0.377358490566038 1.32934887651869 0.0231347328991758 0.10349345743969 GO:0070034 telomerase RNA binding 11/5291 22/18639 0.5 1.76138726138726 0.0260188869993442 0.116011605069683 GO:0005543 phospholipid binding 161/5291 497/18639 0.323943661971831 1.14118047920865 0.0261761951777457 0.116329077911626 GO:0140311 protein sequestering activity 15/5291 33/18639 0.454545454545455 1.60126114671569 0.0271692781797022 0.120346540395992 GO:0004879 nuclear receptor activity 24/5291 59/18639 0.406779661016949 1.43299302621337 0.0282710168184935 0.122675548720918 GO:0045309 protein phosphorylated amino acid binding 24/5291 59/18639 0.406779661016949 1.43299302621337 0.0282710168184935 0.122675548720918 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 9/5291 17/18639 0.529411764705882 1.86499827676298 0.0284333867447456 0.122675548720918 GO:0038191 neuropilin binding 9/5291 17/18639 0.529411764705882 1.86499827676298 0.0284333867447456 0.122675548720918 GO:0000340 RNA 7-methylguanosine cap binding 7/5291 12/18639 0.583333333333333 2.0549518049518 0.0286939107296891 0.122675548720918 GO:0005049 nuclear export signal receptor activity 7/5291 12/18639 0.583333333333333 2.0549518049518 0.0286939107296891 0.122675548720918 GO:0005078 MAP-kinase scaffold activity 7/5291 12/18639 0.583333333333333 2.0549518049518 0.0286939107296891 0.122675548720918 GO:0005095 GTPase inhibitor activity 7/5291 12/18639 0.583333333333333 2.0549518049518 0.0286939107296891 0.122675548720918 GO:0035497 cAMP response element binding 7/5291 12/18639 0.583333333333333 2.0549518049518 0.0286939107296891 0.122675548720918 GO:0141221 histone deacetylase activity, hydrolytic mechanism 7/5291 12/18639 0.583333333333333 2.0549518049518 0.0286939107296891 0.122675548720918 GO:1990817 poly(A) RNA polymerase activity 7/5291 12/18639 0.583333333333333 2.0549518049518 0.0286939107296891 0.122675548720918 GO:0055106 ubiquitin-protein transferase regulator activity 16/5291 36/18639 0.444444444444444 1.56567756567757 0.0288054454978661 0.12276390179059 GO:0004709 MAP kinase kinase kinase activity 12/5291 25/18639 0.48 1.69093177093177 0.0292637032180798 0.123547697023831 GO:0019211 phosphatase activator activity 12/5291 25/18639 0.48 1.69093177093177 0.0292637032180798 0.123547697023831 GO:0042974 nuclear retinoic acid receptor binding 12/5291 25/18639 0.48 1.69093177093177 0.0292637032180798 0.123547697023831 GO:0000217 DNA secondary structure binding 17/5291 39/18639 0.435897435897436 1.53556838172223 0.0301825209583096 0.127029862351016 GO:0019894 kinesin binding 18/5291 42/18639 0.428571428571429 1.50976050976051 0.0313308059714672 0.131453164184634 GO:0000339 RNA cap binding 10/5291 20/18639 0.5 1.76138726138726 0.0333204288419985 0.13808558087589 GO:0043024 ribosomal small subunit binding 10/5291 20/18639 0.5 1.76138726138726 0.0333204288419985 0.13808558087589 GO:0052745 inositol phosphate phosphatase activity 10/5291 20/18639 0.5 1.76138726138726 0.0333204288419985 0.13808558087589 GO:0140664 ATP-dependent DNA damage sensor activity 10/5291 20/18639 0.5 1.76138726138726 0.0333204288419985 0.13808558087589 GO:0003743 translation initiation factor activity 21/5291 51/18639 0.411764705882353 1.4505542152601 0.0336621408986578 0.138651074250264 GO:0030544 Hsp70 protein binding 21/5291 51/18639 0.411764705882353 1.4505542152601 0.0336621408986578 0.138651074250264 GO:0140463 chromatin-protein adaptor activity 22/5291 54/18639 0.407407407407407 1.43520443520444 0.0341402102599671 0.140192778301567 GO:0017147 Wnt-protein binding 14/5291 31/18639 0.451612903225806 1.59093042964011 0.0342727473812971 0.140310550642825 GO:0002039 p53 binding 27/5291 69/18639 0.391304347826087 1.37847698717264 0.0349995550839007 0.142853168937613 GO:0015035 protein-disulfide reductase activity 15/5291 34/18639 0.441176470588235 1.55416523063582 0.0361575206980698 0.144365001991156 GO:0005381 iron ion transmembrane transporter activity 6/5291 10/18639 0.6 2.11366471366471 0.036467054777232 0.144365001991156 GO:0031434 mitogen-activated protein kinase kinase binding 6/5291 10/18639 0.6 2.11366471366471 0.036467054777232 0.144365001991156 GO:0031996 thioesterase binding 6/5291 10/18639 0.6 2.11366471366471 0.036467054777232 0.144365001991156 GO:0032356 oxidized DNA binding 6/5291 10/18639 0.6 2.11366471366471 0.036467054777232 0.144365001991156 GO:0099122 RNA polymerase II C-terminal domain binding 6/5291 10/18639 0.6 2.11366471366471 0.036467054777232 0.144365001991156 GO:0031005 filamin binding 8/5291 15/18639 0.533333333333333 1.87881307881308 0.0365453965070136 0.144365001991156 GO:0042809 nuclear vitamin D receptor binding 8/5291 15/18639 0.533333333333333 1.87881307881308 0.0365453965070136 0.144365001991156 GO:0120283 protein serine/threonine kinase binding 8/5291 15/18639 0.533333333333333 1.87881307881308 0.0365453965070136 0.144365001991156 GO:0141050 histone H3K deacetylase activity 8/5291 15/18639 0.533333333333333 1.87881307881308 0.0365453965070136 0.144365001991156 GO:0141051 histone H4K deacetylase activity 8/5291 15/18639 0.533333333333333 1.87881307881308 0.0365453965070136 0.144365001991156 GO:0003887 DNA-directed DNA polymerase activity 11/5291 23/18639 0.478260869565217 1.68480520654434 0.0373451909199855 0.147094323419535 GO:0004712 protein serine/threonine/tyrosine kinase activity 18/5291 43/18639 0.418604651162791 1.4746498002312 0.0399525171278285 0.156511736012868 GO:0008017 microtubule binding 92/5291 276/18639 0.333333333333333 1.17425817425817 0.0399678378419242 0.156511736012868 GO:0097602 cullin family protein binding 12/5291 26/18639 0.461538461538462 1.62589593358824 0.0406286297651849 0.158639534140939 GO:0060590 ATPase regulator activity 20/5291 49/18639 0.408163265306122 1.43786715215287 0.0413267354963134 0.160900344828586 GO:0030159 signaling receptor complex adaptor activity 21/5291 52/18639 0.403846153846154 1.42265894188971 0.0417576186020135 0.162110754975058 GO:0008173 RNA methyltransferase activity 26/5291 67/18639 0.388059701492537 1.3670468297334 0.0421477188445535 0.163156355756424 GO:0015631 tubulin binding 125/5291 385/18639 0.324675324675325 1.14375796193978 0.0424561180754162 0.163880615771107 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 9/5291 18/18639 0.5 1.76138726138726 0.0428280538772837 0.16391133367765 GO:0031690 adrenergic receptor binding 9/5291 18/18639 0.5 1.76138726138726 0.0428280538772837 0.16391133367765 GO:0070628 proteasome binding 9/5291 18/18639 0.5 1.76138726138726 0.0428280538772837 0.16391133367765 GO:0004535 poly(A)-specific ribonuclease activity 7/5291 13/18639 0.538461538461538 1.89687858918628 0.0471885079598579 0.178576118357894 GO:0031994 insulin-like growth factor I binding 7/5291 13/18639 0.538461538461538 1.89687858918628 0.0471885079598579 0.178576118357894 GO:0043560 insulin receptor substrate binding 7/5291 13/18639 0.538461538461538 1.89687858918628 0.0471885079598579 0.178576118357894 GO:0070123 transforming growth factor beta receptor activity, type III 7/5291 13/18639 0.538461538461538 1.89687858918628 0.0471885079598579 0.178576118357894 GO:0010314 phosphatidylinositol-5-phosphate binding 10/5291 21/18639 0.476190476190476 1.67751167751168 0.0477980059772146 0.180377391271556 GO:0005109 frizzled binding 16/5291 38/18639 0.421052631578947 1.48327348327348 0.0484219388313842 0.182222950866852 GO:0140299 molecular sensor activity 27/5291 71/18639 0.380281690140845 1.3396466495058 0.0499220286278592 0.187346279656216 GO:0001046 core promoter sequence-specific DNA binding 18/5291 44/18639 0.409090909090909 1.44113503204412 0.0501682861986309 0.187748904859696 GO:0030145 manganese ion binding 26/5291 68/18639 0.382352941176471 1.34694319988438 0.0503272759591184 0.187823618289417 GO:0015605 organophosphate ester transmembrane transporter activity 20/5291 50/18639 0.4 1.40910980910981 0.0510151041197203 0.189866131310584 GO:0001091 RNA polymerase II general transcription initiation factor binding 11/5291 24/18639 0.458333333333333 1.61460498960499 0.0517004789640602 0.191135971164915 GO:0050431 transforming growth factor beta binding 11/5291 24/18639 0.458333333333333 1.61460498960499 0.0517004789640602 0.191135971164915 GO:0004540 RNA nuclease activity 43/5291 121/18639 0.355371900826446 1.25189507834136 0.0517807294199547 0.191135971164915 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 12/5291 27/18639 0.444444444444444 1.56567756567757 0.0547407671424896 0.200817965606642 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 8/5291 16/18639 0.5 1.76138726138726 0.0552955464142641 0.200817965606642 GO:0008142 oxysterol binding 8/5291 16/18639 0.5 1.76138726138726 0.0552955464142641 0.200817965606642 GO:0008296 3'-5'-DNA exonuclease activity 8/5291 16/18639 0.5 1.76138726138726 0.0552955464142641 0.200817965606642 GO:0030275 LRR domain binding 8/5291 16/18639 0.5 1.76138726138726 0.0552955464142641 0.200817965606642 GO:0031435 mitogen-activated protein kinase kinase kinase binding 8/5291 16/18639 0.5 1.76138726138726 0.0552955464142641 0.200817965606642 GO:0015215 nucleotide transmembrane transporter activity 13/5291 30/18639 0.433333333333333 1.52653562653563 0.0570838224529729 0.206756686686237 GO:0019199 transmembrane receptor protein kinase activity 29/5291 78/18639 0.371794871794872 1.30974950205719 0.0574159755705858 0.207403697849897 GO:0016853 isomerase activity 61/5291 180/18639 0.338888888888889 1.19382914382914 0.0609067910202772 0.214305451011965 GO:0016776 phosphotransferase activity, phosphate group as acceptor 16/5291 39/18639 0.41025641025641 1.44524082985621 0.061110229525697 0.214305451011965 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 6/5291 11/18639 0.545454545454545 1.92151337605883 0.061286045318748 0.214305451011965 GO:0005225 volume-sensitive anion channel activity 6/5291 11/18639 0.545454545454545 1.92151337605883 0.061286045318748 0.214305451011965 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 6/5291 11/18639 0.545454545454545 1.92151337605883 0.061286045318748 0.214305451011965 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 6/5291 11/18639 0.545454545454545 1.92151337605883 0.061286045318748 0.214305451011965 GO:0034713 type I transforming growth factor beta receptor binding 6/5291 11/18639 0.545454545454545 1.92151337605883 0.061286045318748 0.214305451011965 GO:0043522 leucine zipper domain binding 6/5291 11/18639 0.545454545454545 1.92151337605883 0.061286045318748 0.214305451011965 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 6/5291 11/18639 0.545454545454545 1.92151337605883 0.061286045318748 0.214305451011965 GO:0180030 inositol phosphate kinase activity 6/5291 11/18639 0.545454545454545 1.92151337605883 0.061286045318748 0.214305451011965 GO:0005346 purine ribonucleotide transmembrane transporter activity 9/5291 19/18639 0.473684210526316 1.66868266868267 0.0613887561374023 0.214305451011965 GO:0005520 insulin-like growth factor binding 9/5291 19/18639 0.473684210526316 1.66868266868267 0.0613887561374023 0.214305451011965 GO:0050145 nucleoside monophosphate kinase activity 9/5291 19/18639 0.473684210526316 1.66868266868267 0.0613887561374023 0.214305451011965 GO:0004407 histone deacetylase activity 10/5291 22/18639 0.454545454545455 1.60126114671569 0.0659472717921063 0.22903538352477 GO:0033558 protein lysine deacetylase activity 10/5291 22/18639 0.454545454545455 1.60126114671569 0.0659472717921063 0.22903538352477 GO:0008139 nuclear localization sequence binding 11/5291 25/18639 0.44 1.55002079002079 0.0693293741930446 0.240164062909752 GO:0005545 1-phosphatidylinositol binding 7/5291 14/18639 0.5 1.76138726138726 0.0717917040389474 0.244188332703756 GO:0008191 metalloendopeptidase inhibitor activity 7/5291 14/18639 0.5 1.76138726138726 0.0717917040389474 0.244188332703756 GO:0032454 histone H3K9 demethylase activity 7/5291 14/18639 0.5 1.76138726138726 0.0717917040389474 0.244188332703756 GO:0061665 SUMO ligase activity 7/5291 14/18639 0.5 1.76138726138726 0.0717917040389474 0.244188332703756 GO:0070742 C2H2 zinc finger domain binding 7/5291 14/18639 0.5 1.76138726138726 0.0717917040389474 0.244188332703756 GO:0051019 mitogen-activated protein kinase binding 12/5291 28/18639 0.428571428571429 1.50976050976051 0.0718004680296636 0.244188332703756 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 12/5291 28/18639 0.428571428571429 1.50976050976051 0.0718004680296636 0.244188332703756 GO:0004536 DNA nuclease activity 24/5291 64/18639 0.375 1.32104044604045 0.0719370513812692 0.244188332703756 GO:0004713 protein tyrosine kinase activity 48/5291 140/18639 0.342857142857143 1.20780840780841 0.0739977568720273 0.250553808356163 GO:0008175 tRNA methyltransferase activity 14/5291 34/18639 0.411764705882353 1.4505542152601 0.0747527990184119 0.252477578684686 GO:0015036 disulfide oxidoreductase activity 16/5291 40/18639 0.4 1.40910980910981 0.0758812587966803 0.255173715283511 GO:0008135 translation factor activity, RNA binding 30/5291 83/18639 0.36144578313253 1.27329199618356 0.0759288183153007 0.255173715283511 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 8/5291 17/18639 0.470588235294118 1.65777624601154 0.0791730216760583 0.26286843272856 GO:0015278 intracellularly gated calcium channel activity 8/5291 17/18639 0.470588235294118 1.65777624601154 0.0791730216760583 0.26286843272856 GO:0046965 nuclear retinoid X receptor binding 8/5291 17/18639 0.470588235294118 1.65777624601154 0.0791730216760583 0.26286843272856 GO:0051787 misfolded protein binding 8/5291 17/18639 0.470588235294118 1.65777624601154 0.0791730216760583 0.26286843272856 GO:0035401 histone H3Y41 kinase activity 40/5291 115/18639 0.347826086956522 1.22531287748679 0.0793858775375667 0.26286843272856 GO:0140801 histone H2AXY142 kinase activity 40/5291 115/18639 0.347826086956522 1.22531287748679 0.0793858775375667 0.26286843272856 GO:0180051 translation factor activity 30/5291 84/18639 0.357142857142857 1.25813375813376 0.0871053963945439 0.287724671220119 GO:0008171 O-methyltransferase activity 10/5291 23/18639 0.434782608695652 1.53164109685849 0.0879488724629688 0.289097145249321 GO:0017134 fibroblast growth factor binding 10/5291 23/18639 0.434782608695652 1.53164109685849 0.0879488724629688 0.289097145249321 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 11/5291 26/18639 0.423076923076923 1.49040460578922 0.0903765867734753 0.294952141989412 GO:0043548 phosphatidylinositol 3-kinase binding 11/5291 26/18639 0.423076923076923 1.49040460578922 0.0903765867734753 0.294952141989412 GO:0005007 fibroblast growth factor receptor activity 19/5291 50/18639 0.38 1.33865431865432 0.090490143685574 0.294952141989412 GO:0001784 phosphotyrosine residue binding 18/5291 47/18639 0.382978723404255 1.34914768957322 0.091432998570444 0.294952141989412 GO:0140359 ABC-type transporter activity 18/5291 47/18639 0.382978723404255 1.34914768957322 0.091432998570444 0.294952141989412 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 16/5291 41/18639 0.390243902439024 1.3747412771803 0.092811992191515 0.294952141989412 GO:0016410 N-acyltransferase activity 33/5291 94/18639 0.351063829787234 1.23671871544212 0.0928914124763624 0.294952141989412 GO:0042162 telomeric DNA binding 15/5291 38/18639 0.394736842105263 1.39056889056889 0.0931556187413372 0.294952141989412 GO:0000995 RNA polymerase III general transcription initiation factor activity 6/5291 12/18639 0.5 1.76138726138726 0.093878179907807 0.294952141989412 GO:0004300 enoyl-CoA hydratase activity 6/5291 12/18639 0.5 1.76138726138726 0.093878179907807 0.294952141989412 GO:0005025 transforming growth factor beta receptor activity, type I 6/5291 12/18639 0.5 1.76138726138726 0.093878179907807 0.294952141989412 GO:0005026 transforming growth factor beta receptor activity, type II 6/5291 12/18639 0.5 1.76138726138726 0.093878179907807 0.294952141989412 GO:0016361 activin receptor activity, type I 6/5291 12/18639 0.5 1.76138726138726 0.093878179907807 0.294952141989412 GO:0016362 activin receptor activity, type II 6/5291 12/18639 0.5 1.76138726138726 0.093878179907807 0.294952141989412 GO:0017002 activin receptor activity 6/5291 12/18639 0.5 1.76138726138726 0.093878179907807 0.294952141989412 GO:0035197 siRNA binding 6/5291 12/18639 0.5 1.76138726138726 0.093878179907807 0.294952141989412 GO:0035259 nuclear glucocorticoid receptor binding 6/5291 12/18639 0.5 1.76138726138726 0.093878179907807 0.294952141989412 GO:0043047 single-stranded telomeric DNA binding 6/5291 12/18639 0.5 1.76138726138726 0.093878179907807 0.294952141989412 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 6/5291 12/18639 0.5 1.76138726138726 0.093878179907807 0.294952141989412 GO:0000774 adenyl-nucleotide exchange factor activity 7/5291 15/18639 0.466666666666667 1.64396144396144 0.102632223129389 0.317290923221521 GO:0004559 alpha-mannosidase activity 7/5291 15/18639 0.466666666666667 1.64396144396144 0.102632223129389 0.317290923221521 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 7/5291 15/18639 0.466666666666667 1.64396144396144 0.102632223129389 0.317290923221521 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 7/5291 15/18639 0.466666666666667 1.64396144396144 0.102632223129389 0.317290923221521 GO:0050780 dopamine receptor binding 7/5291 15/18639 0.466666666666667 1.64396144396144 0.102632223129389 0.317290923221521 GO:0051371 muscle alpha-actinin binding 7/5291 15/18639 0.466666666666667 1.64396144396144 0.102632223129389 0.317290923221521 GO:0061578 K63-linked deubiquitinase activity 7/5291 15/18639 0.466666666666667 1.64396144396144 0.102632223129389 0.317290923221521 GO:0015932 nucleobase-containing compound transmembrane transporter activity 21/5291 57/18639 0.368421052631579 1.2978642978643 0.103744597230188 0.319997604698595 GO:0005010 insulin-like growth factor receptor activity 19/5291 51/18639 0.372549019607843 1.31240619475914 0.107281143968118 0.330122784382101 GO:0004706 JUN kinase kinase kinase activity 8/5291 18/18639 0.444444444444444 1.56567756567757 0.108248995915078 0.330122784382101 GO:0008308 voltage-gated monoatomic anion channel activity 8/5291 18/18639 0.444444444444444 1.56567756567757 0.108248995915078 0.330122784382101 GO:0070064 proline-rich region binding 8/5291 18/18639 0.444444444444444 1.56567756567757 0.108248995915078 0.330122784382101 GO:0098641 cadherin binding involved in cell-cell adhesion 8/5291 18/18639 0.444444444444444 1.56567756567757 0.108248995915078 0.330122784382101 GO:0140693 molecular condensate scaffold activity 18/5291 48/18639 0.375 1.32104044604045 0.108947122194999 0.331503518210458 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 9/5291 21/18639 0.428571428571429 1.50976050976051 0.111770560112326 0.336307409157576 GO:0009931 calcium-dependent protein serine/threonine kinase activity 9/5291 21/18639 0.428571428571429 1.50976050976051 0.111770560112326 0.336307409157576 GO:0009975 cyclase activity 9/5291 21/18639 0.428571428571429 1.50976050976051 0.111770560112326 0.336307409157576 GO:0051010 microtubule plus-end binding 9/5291 21/18639 0.428571428571429 1.50976050976051 0.111770560112326 0.336307409157576 GO:0072542 protein phosphatase activator activity 9/5291 21/18639 0.428571428571429 1.50976050976051 0.111770560112326 0.336307409157576 GO:0005385 zinc ion transmembrane transporter activity 11/5291 27/18639 0.407407407407407 1.43520443520444 0.114876212769778 0.344883918782156 GO:0051213 dioxygenase activity 32/5291 93/18639 0.344086021505376 1.21213747020199 0.120846505712586 0.359303701006028 GO:0003678 DNA helicase activity 26/5291 74/18639 0.351351351351351 1.23773158908294 0.12387856356475 0.359303701006028 GO:0008641 ubiquitin-like modifier activating enzyme activity 5/5291 10/18639 0.5 1.76138726138726 0.123934511227838 0.359303701006028 GO:0015924 mannosyl-oligosaccharide mannosidase activity 5/5291 10/18639 0.5 1.76138726138726 0.123934511227838 0.359303701006028 GO:0016303 1-phosphatidylinositol-3-kinase activity 5/5291 10/18639 0.5 1.76138726138726 0.123934511227838 0.359303701006028 GO:0016427 tRNA (cytidine) methyltransferase activity 5/5291 10/18639 0.5 1.76138726138726 0.123934511227838 0.359303701006028 GO:0016783 sulfurtransferase activity 5/5291 10/18639 0.5 1.76138726138726 0.123934511227838 0.359303701006028 GO:0030957 Tat protein binding 5/5291 10/18639 0.5 1.76138726138726 0.123934511227838 0.359303701006028 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 5/5291 10/18639 0.5 1.76138726138726 0.123934511227838 0.359303701006028 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 5/5291 10/18639 0.5 1.76138726138726 0.123934511227838 0.359303701006028 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 5/5291 10/18639 0.5 1.76138726138726 0.123934511227838 0.359303701006028 GO:0045322 unmethylated CpG binding 5/5291 10/18639 0.5 1.76138726138726 0.123934511227838 0.359303701006028 GO:0070513 death domain binding 5/5291 10/18639 0.5 1.76138726138726 0.123934511227838 0.359303701006028 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 5/5291 10/18639 0.5 1.76138726138726 0.123934511227838 0.359303701006028 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 5/5291 10/18639 0.5 1.76138726138726 0.123934511227838 0.359303701006028 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 5/5291 10/18639 0.5 1.76138726138726 0.123934511227838 0.359303701006028 GO:0070851 growth factor receptor binding 46/5291 139/18639 0.330935251798561 1.16581027372394 0.127649447985505 0.363591922138546 GO:0005004 GPI-linked ephrin receptor activity 18/5291 49/18639 0.36734693877551 1.29408043693758 0.128374053930486 0.363591922138546 GO:0005008 hepatocyte growth factor receptor activity 18/5291 49/18639 0.36734693877551 1.29408043693758 0.128374053930486 0.363591922138546 GO:0005009 insulin receptor activity 18/5291 49/18639 0.36734693877551 1.29408043693758 0.128374053930486 0.363591922138546 GO:0005011 macrophage colony-stimulating factor receptor activity 18/5291 49/18639 0.36734693877551 1.29408043693758 0.128374053930486 0.363591922138546 GO:0005018 platelet-derived growth factor alpha-receptor activity 18/5291 49/18639 0.36734693877551 1.29408043693758 0.128374053930486 0.363591922138546 GO:0005020 stem cell factor receptor activity 18/5291 49/18639 0.36734693877551 1.29408043693758 0.128374053930486 0.363591922138546 GO:0008288 boss receptor activity 18/5291 49/18639 0.36734693877551 1.29408043693758 0.128374053930486 0.363591922138546 GO:0036332 placental growth factor receptor activity 18/5291 49/18639 0.36734693877551 1.29408043693758 0.128374053930486 0.363591922138546 GO:0038062 protein tyrosine kinase collagen receptor activity 18/5291 49/18639 0.36734693877551 1.29408043693758 0.128374053930486 0.363591922138546 GO:0060175 brain-derived neurotrophic factor receptor activity 18/5291 49/18639 0.36734693877551 1.29408043693758 0.128374053930486 0.363591922138546 GO:0005172 vascular endothelial growth factor receptor binding 6/5291 13/18639 0.461538461538462 1.62589593358824 0.133897898720335 0.377653572382406 GO:0005338 nucleotide-sugar transmembrane transporter activity 6/5291 13/18639 0.461538461538462 1.62589593358824 0.133897898720335 0.377653572382406 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 15/5291 40/18639 0.375 1.32104044604045 0.135565623923771 0.381560745668781 GO:0042805 actinin binding 14/5291 37/18639 0.378378378378378 1.33294171132009 0.137744072468045 0.386239683804039 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 7/5291 16/18639 0.4375 1.54121385371385 0.139449638352264 0.386239683804039 GO:0015923 mannosidase activity 7/5291 16/18639 0.4375 1.54121385371385 0.139449638352264 0.386239683804039 GO:0016722 oxidoreductase activity, acting on metal ions 7/5291 16/18639 0.4375 1.54121385371385 0.139449638352264 0.386239683804039 GO:0034450 ubiquitin-ubiquitin ligase activity 7/5291 16/18639 0.4375 1.54121385371385 0.139449638352264 0.386239683804039 GO:0097027 ubiquitin-protein transferase activator activity 7/5291 16/18639 0.4375 1.54121385371385 0.139449638352264 0.386239683804039 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 7/5291 16/18639 0.4375 1.54121385371385 0.139449638352264 0.386239683804039 GO:0036002 pre-mRNA binding 21/5291 59/18639 0.355932203389831 1.25386889793669 0.139515148553939 0.386239683804039 GO:0046527 glucosyltransferase activity 8/5291 19/18639 0.421052631578947 1.48327348327348 0.142329170298842 0.392777120075035 GO:0004197 cysteine-type endopeptidase activity 30/5291 88/18639 0.340909090909091 1.20094586003677 0.142459488515536 0.392777120075035 GO:0097718 disordered domain specific binding 11/5291 28/18639 0.392857142857143 1.38394713394713 0.142748753483969 0.392777120075035 GO:0008093 cytoskeletal anchor activity 9/5291 22/18639 0.409090909090909 1.44113503204412 0.143494375103247 0.39328273363758 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 10/5291 25/18639 0.4 1.40910980910981 0.143514720713047 0.39328273363758 GO:0016829 lyase activity 64/5291 200/18639 0.32 1.12728784728785 0.144677495248699 0.395666591257069 GO:0016757 glycosyltransferase activity 84/5291 267/18639 0.314606741573034 1.10828861390659 0.146194834435688 0.396778780830314 GO:0038064 collagen receptor activity 19/5291 53/18639 0.358490566037736 1.26288143269275 0.146238058499658 0.396778780830314 GO:0051018 protein kinase A binding 19/5291 53/18639 0.358490566037736 1.26288143269275 0.146238058499658 0.396778780830314 GO:1902936 phosphatidylinositol bisphosphate binding 37/5291 111/18639 0.333333333333333 1.17425817425817 0.146258943636933 0.396778780830314 GO:0005006 epidermal growth factor receptor activity 18/5291 50/18639 0.36 1.26819882819883 0.149683753443249 0.402834165143086 GO:0005017 platelet-derived growth factor receptor activity 18/5291 50/18639 0.36 1.26819882819883 0.149683753443249 0.402834165143086 GO:0005019 platelet-derived growth factor beta-receptor activity 18/5291 50/18639 0.36 1.26819882819883 0.149683753443249 0.402834165143086 GO:0032813 tumor necrosis factor receptor superfamily binding 18/5291 50/18639 0.36 1.26819882819883 0.149683753443249 0.402834165143086 GO:0017124 SH3 domain binding 38/5291 115/18639 0.330434782608696 1.16404723361245 0.156864293373894 0.421319404270639 GO:0017022 myosin binding 26/5291 76/18639 0.342105263157895 1.20515970515971 0.158323547389773 0.424395064530918 GO:0001727 lipid kinase activity 15/5291 41/18639 0.365853658536585 1.28881994735653 0.160231180692381 0.428658069535458 GO:0034061 DNA polymerase activity 13/5291 35/18639 0.371428571428571 1.30845910845911 0.167228486390257 0.446493448840389 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 72/5291 229/18639 0.314410480349345 1.10759722986797 0.168849551172239 0.449932433202554 GO:0051059 NF-kappaB binding 12/5291 32/18639 0.375 1.32104044604045 0.170603512867468 0.45360454307689 GO:0005021 vascular endothelial growth factor receptor activity 18/5291 51/18639 0.352941176470588 1.24333218450866 0.172812449520593 0.45360454307689 GO:0005030 neurotrophin receptor activity 18/5291 51/18639 0.352941176470588 1.24333218450866 0.172812449520593 0.45360454307689 GO:0016830 carbon-carbon lyase activity 18/5291 51/18639 0.352941176470588 1.24333218450866 0.172812449520593 0.45360454307689 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 11/5291 29/18639 0.379310344827586 1.33622481898344 0.173805438978524 0.45360454307689 GO:0106222 lncRNA binding 11/5291 29/18639 0.379310344827586 1.33622481898344 0.173805438978524 0.45360454307689 GO:0002162 dystroglycan binding 5/5291 11/18639 0.454545454545455 1.60126114671569 0.176141566152079 0.45360454307689 GO:0032050 clathrin heavy chain binding 5/5291 11/18639 0.454545454545455 1.60126114671569 0.176141566152079 0.45360454307689 GO:0045294 alpha-catenin binding 5/5291 11/18639 0.454545454545455 1.60126114671569 0.176141566152079 0.45360454307689 GO:0070990 snRNP binding 5/5291 11/18639 0.454545454545455 1.60126114671569 0.176141566152079 0.45360454307689 GO:0097493 structural molecule activity conferring elasticity 5/5291 11/18639 0.454545454545455 1.60126114671569 0.176141566152079 0.45360454307689 GO:0140031 phosphorylation-dependent protein binding 5/5291 11/18639 0.454545454545455 1.60126114671569 0.176141566152079 0.45360454307689 GO:0004529 DNA exonuclease activity 10/5291 26/18639 0.384615384615385 1.3549132779902 0.17672605442528 0.45360454307689 GO:0015216 purine nucleotide transmembrane transporter activity 10/5291 26/18639 0.384615384615385 1.3549132779902 0.17672605442528 0.45360454307689 GO:0034237 protein kinase A regulatory subunit binding 10/5291 26/18639 0.384615384615385 1.3549132779902 0.17672605442528 0.45360454307689 GO:0070006 metalloaminopeptidase activity 10/5291 26/18639 0.384615384615385 1.3549132779902 0.17672605442528 0.45360454307689 GO:0016879 ligase activity, forming carbon-nitrogen bonds 17/5291 48/18639 0.354166666666667 1.24764931014931 0.177427609091934 0.45360454307689 GO:0000295 adenine nucleotide transmembrane transporter activity 9/5291 23/18639 0.391304347826087 1.37847698717264 0.17920219822914 0.45360454307689 GO:0070577 lysine-acetylated histone binding 9/5291 23/18639 0.391304347826087 1.37847698717264 0.17920219822914 0.45360454307689 GO:0005347 ATP transmembrane transporter activity 6/5291 14/18639 0.428571428571429 1.50976050976051 0.180477544731375 0.45360454307689 GO:0019992 diacylglycerol binding 6/5291 14/18639 0.428571428571429 1.50976050976051 0.180477544731375 0.45360454307689 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 6/5291 14/18639 0.428571428571429 1.50976050976051 0.180477544731375 0.45360454307689 GO:0042043 neurexin family protein binding 6/5291 14/18639 0.428571428571429 1.50976050976051 0.180477544731375 0.45360454307689 GO:0046030 inositol trisphosphate phosphatase activity 6/5291 14/18639 0.428571428571429 1.50976050976051 0.180477544731375 0.45360454307689 GO:0071933 Arp2/3 complex binding 6/5291 14/18639 0.428571428571429 1.50976050976051 0.180477544731375 0.45360454307689 GO:0098821 BMP receptor activity 6/5291 14/18639 0.428571428571429 1.50976050976051 0.180477544731375 0.45360454307689 GO:0015095 magnesium ion transmembrane transporter activity 8/5291 20/18639 0.4 1.40910980910981 0.180979449699885 0.45360454307689 GO:0016004 phospholipase activator activity 8/5291 20/18639 0.4 1.40910980910981 0.180979449699885 0.45360454307689 GO:0016505 peptidase activator activity involved in apoptotic process 8/5291 20/18639 0.4 1.40910980910981 0.180979449699885 0.45360454307689 GO:0140939 histone H4 methyltransferase activity 8/5291 20/18639 0.4 1.40910980910981 0.180979449699885 0.45360454307689 GO:0019905 syntaxin binding 21/5291 61/18639 0.344262295081967 1.21275844226664 0.181519384524643 0.45360454307689 GO:0004659 prenyltransferase activity 7/5291 17/18639 0.411764705882353 1.4505542152601 0.181643270025609 0.45360454307689 GO:0005092 GDP-dissociation inhibitor activity 7/5291 17/18639 0.411764705882353 1.4505542152601 0.181643270025609 0.45360454307689 GO:1990226 histone methyltransferase binding 7/5291 17/18639 0.411764705882353 1.4505542152601 0.181643270025609 0.45360454307689 GO:0140303 intramembrane lipid transporter activity 16/5291 45/18639 0.355555555555556 1.25254205254205 0.18217748878414 0.453848412945896 GO:0003684 damaged DNA binding 25/5291 74/18639 0.337837837837838 1.19012652796437 0.18241279661704 0.453848412945896 GO:0051117 ATPase binding 28/5291 84/18639 0.333333333333333 1.17425817425817 0.186637108794605 0.462855522030988 GO:0004520 DNA endonuclease activity 15/5291 42/18639 0.357142857142857 1.25813375813376 0.187060780924441 0.462855522030988 GO:0048487 beta-tubulin binding 15/5291 42/18639 0.357142857142857 1.25813375813376 0.187060780924441 0.462855522030988 GO:0004519 endonuclease activity 41/5291 127/18639 0.322834645669291 1.13727366483272 0.188932553108055 0.466632320382051 GO:0030971 receptor tyrosine kinase binding 27/5291 81/18639 0.333333333333333 1.17425817425817 0.191998191247734 0.472654412309411 GO:0140313 molecular sequestering activity 19/5291 55/18639 0.345454545454545 1.21695847150393 0.19207051987999 0.472654412309411 GO:0140223 general transcription initiation factor activity 23/5291 68/18639 0.338235294117647 1.19152667682079 0.193107089945443 0.474341233665989 GO:0005484 SNAP receptor activity 13/5291 36/18639 0.361111111111111 1.27211302211302 0.197205999217218 0.483530498988134 GO:0001671 ATPase activator activity 10/5291 27/18639 0.37037037037037 1.3047313047313 0.213108314222634 0.520631704366688 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 10/5291 27/18639 0.37037037037037 1.3047313047313 0.213108314222634 0.520631704366688 GO:0048027 mRNA 5'-UTR binding 9/5291 24/18639 0.375 1.32104044604045 0.218419167903596 0.529774319277842 GO:0060229 lipase activator activity 9/5291 24/18639 0.375 1.32104044604045 0.218419167903596 0.529774319277842 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 9/5291 24/18639 0.375 1.32104044604045 0.218419167903596 0.529774319277842 GO:0140033 acetylation-dependent protein binding 9/5291 24/18639 0.375 1.32104044604045 0.218419167903596 0.529774319277842 GO:0005123 death receptor binding 8/5291 21/18639 0.380952380952381 1.34200934200934 0.223569535599921 0.538744674056504 GO:0140312 cargo adaptor activity 8/5291 21/18639 0.380952380952381 1.34200934200934 0.223569535599921 0.538744674056504 GO:0005003 ephrin receptor activity 18/5291 53/18639 0.339622641509434 1.19641398886682 0.224111404011662 0.538744674056504 GO:0005005 transmembrane-ephrin receptor activity 18/5291 53/18639 0.339622641509434 1.19641398886682 0.224111404011662 0.538744674056504 GO:0016251 RNA polymerase II general transcription initiation factor activity 18/5291 53/18639 0.339622641509434 1.19641398886682 0.224111404011662 0.538744674056504 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 28/5291 86/18639 0.325581395348837 1.14694984462426 0.227324160115835 0.544530036022152 GO:0050660 flavin adenine dinucleotide binding 28/5291 86/18639 0.325581395348837 1.14694984462426 0.227324160115835 0.544530036022152 GO:1990381 ubiquitin-specific protease binding 7/5291 18/18639 0.388888888888889 1.36996786996787 0.228348717186856 0.546016136140605 GO:0019213 deacetylase activity 13/5291 37/18639 0.351351351351351 1.23773158908294 0.22941454287302 0.547595490143906 GO:0017166 vinculin binding 5/5291 12/18639 0.416666666666667 1.46782271782272 0.234901127755131 0.554810181113956 GO:0034452 dynactin binding 5/5291 12/18639 0.416666666666667 1.46782271782272 0.234901127755131 0.554810181113956 GO:0035014 phosphatidylinositol 3-kinase regulator activity 5/5291 12/18639 0.416666666666667 1.46782271782272 0.234901127755131 0.554810181113956 GO:0045295 gamma-catenin binding 5/5291 12/18639 0.416666666666667 1.46782271782272 0.234901127755131 0.554810181113956 GO:0097677 STAT family protein binding 5/5291 12/18639 0.416666666666667 1.46782271782272 0.234901127755131 0.554810181113956 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 5/5291 12/18639 0.416666666666667 1.46782271782272 0.234901127755131 0.554810181113956 GO:0004714 transmembrane receptor protein tyrosine kinase activity 20/5291 60/18639 0.333333333333333 1.17425817425817 0.236449393326181 0.557492374142532 GO:0043495 protein-membrane adaptor activity 16/5291 47/18639 0.340425531914894 1.19924239073175 0.238656791351453 0.560739695853588 GO:1990518 single-stranded 3'-5' DNA helicase activity 16/5291 47/18639 0.340425531914894 1.19924239073175 0.238656791351453 0.560739695853588 GO:0005164 tumor necrosis factor receptor binding 11/5291 31/18639 0.354838709677419 1.2500167661458 0.244238355629029 0.572857670928505 GO:0019205 nucleobase-containing compound kinase activity 15/5291 44/18639 0.340909090909091 1.20094586003677 0.246504207176277 0.57648389759495 GO:1990782 protein tyrosine kinase binding 37/5291 117/18639 0.316239316239316 1.1140398063475 0.246991884731171 0.57648389759495 GO:0016500 protein-hormone receptor activity 22/5291 67/18639 0.328358208955224 1.15673193285134 0.247064527540693 0.57648389759495 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 18/5291 54/18639 0.333333333333333 1.17425817425817 0.252001424693931 0.586433892794547 GO:0051393 alpha-actinin binding 10/5291 28/18639 0.357142857142857 1.25813375813376 0.252196959077448 0.586433892794547 GO:0003707 nuclear steroid receptor activity 9/5291 25/18639 0.36 1.26819882819883 0.26055291944828 0.604823014045749 GO:0016836 hydro-lyase activity 20/5291 61/18639 0.327868852459016 1.15500804025394 0.263244519570834 0.610022891835672 GO:0036121 double-stranded DNA helicase activity 16/5291 48/18639 0.333333333333333 1.17425817425817 0.269271382481213 0.620922297779739 GO:0043138 3'-5' DNA helicase activity 16/5291 48/18639 0.333333333333333 1.17425817425817 0.269271382481213 0.620922297779739 GO:0008649 rRNA methyltransferase activity 8/5291 22/18639 0.363636363636364 1.28100891737255 0.26932677016945 0.620922297779739 GO:0043015 gamma-tubulin binding 12/5291 35/18639 0.342857142857143 1.20780840780841 0.272873807214805 0.628028132107669 GO:0042577 lipid phosphatase activity 7/5291 19/18639 0.368421052631579 1.2978642978643 0.278526786204864 0.638101495201762 GO:0120227 acyl-CoA binding 7/5291 19/18639 0.368421052631579 1.2978642978643 0.278526786204864 0.638101495201762 GO:0004715 non-membrane spanning protein tyrosine kinase activity 15/5291 45/18639 0.333333333333333 1.17425817425817 0.278667566372346 0.638101495201762 GO:0031369 translation initiation factor binding 11/5291 32/18639 0.34375 1.21095374220374 0.282808987551752 0.646488903861959 GO:0000062 fatty-acyl-CoA binding 6/5291 16/18639 0.375 1.32104044604045 0.288129298267627 0.652031293064596 GO:0003688 DNA replication origin binding 6/5291 16/18639 0.375 1.32104044604045 0.288129298267627 0.652031293064596 GO:0004708 MAP kinase kinase activity 6/5291 16/18639 0.375 1.32104044604045 0.288129298267627 0.652031293064596 GO:0005159 insulin-like growth factor receptor binding 6/5291 16/18639 0.375 1.32104044604045 0.288129298267627 0.652031293064596 GO:0022858 alanine transmembrane transporter activity 6/5291 16/18639 0.375 1.32104044604045 0.288129298267627 0.652031293064596 GO:0140328 floppase activity 6/5291 16/18639 0.375 1.32104044604045 0.288129298267627 0.652031293064596 GO:0016417 S-acyltransferase activity 10/5291 29/18639 0.344827586206897 1.21474983543949 0.293455653866355 0.662892726007703 GO:0016874 ligase activity 51/5291 167/18639 0.305389221556886 1.07581736923054 0.293910246394237 0.662892726007703 GO:0016835 carbon-oxygen lyase activity 25/5291 79/18639 0.316455696202532 1.11480206416915 0.297543859805072 0.664415883025476 GO:0009982 pseudouridine synthase activity 5/5291 13/18639 0.384615384615385 1.3549132779902 0.298028145901879 0.664415883025476 GO:0039706 co-receptor binding 5/5291 13/18639 0.384615384615385 1.3549132779902 0.298028145901879 0.664415883025476 GO:0046974 histone H3K9 methyltransferase activity 5/5291 13/18639 0.384615384615385 1.3549132779902 0.298028145901879 0.664415883025476 GO:0051011 microtubule minus-end binding 5/5291 13/18639 0.384615384615385 1.3549132779902 0.298028145901879 0.664415883025476 GO:0070700 BMP receptor binding 5/5291 13/18639 0.384615384615385 1.3549132779902 0.298028145901879 0.664415883025476 GO:0140666 annealing activity 5/5291 13/18639 0.384615384615385 1.3549132779902 0.298028145901879 0.664415883025476 GO:0070888 E-box binding 19/5291 59/18639 0.322033898305085 1.13445281241891 0.300975482952116 0.668741942256644 GO:0008198 ferrous iron binding 9/5291 26/18639 0.346153846153846 1.21942195019118 0.304931847989867 0.668741942256644 GO:0050750 low-density lipoprotein particle receptor binding 9/5291 26/18639 0.346153846153846 1.21942195019118 0.304931847989867 0.668741942256644 GO:0098631 cell adhesion mediator activity 24/5291 76/18639 0.315789473684211 1.11245511245511 0.306955013543019 0.668741942256644 GO:0004382 GDP phosphatase activity 4/5291 10/18639 0.4 1.40910980910981 0.307888592215864 0.668741942256644 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 4/5291 10/18639 0.4 1.40910980910981 0.307888592215864 0.668741942256644 GO:0005522 profilin binding 4/5291 10/18639 0.4 1.40910980910981 0.307888592215864 0.668741942256644 GO:0005528 FK506 binding 4/5291 10/18639 0.4 1.40910980910981 0.307888592215864 0.668741942256644 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 4/5291 10/18639 0.4 1.40910980910981 0.307888592215864 0.668741942256644 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 4/5291 10/18639 0.4 1.40910980910981 0.307888592215864 0.668741942256644 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 4/5291 10/18639 0.4 1.40910980910981 0.307888592215864 0.668741942256644 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 4/5291 10/18639 0.4 1.40910980910981 0.307888592215864 0.668741942256644 GO:0043422 protein kinase B binding 4/5291 10/18639 0.4 1.40910980910981 0.307888592215864 0.668741942256644 GO:0050815 phosphoserine residue binding 4/5291 10/18639 0.4 1.40910980910981 0.307888592215864 0.668741942256644 GO:0098505 G-rich strand telomeric DNA binding 4/5291 10/18639 0.4 1.40910980910981 0.307888592215864 0.668741942256644 GO:0140999 histone H3K4 trimethyltransferase activity 4/5291 10/18639 0.4 1.40910980910981 0.307888592215864 0.668741942256644 GO:0016409 palmitoyltransferase activity 12/5291 36/18639 0.333333333333333 1.17425817425817 0.310707711213598 0.673781890609264 GO:0016849 phosphorus-oxygen lyase activity 8/5291 23/18639 0.347826086956522 1.22531287748679 0.317393208537615 0.686077159574909 GO:0140102 catalytic activity, acting on a rRNA 8/5291 23/18639 0.347826086956522 1.22531287748679 0.317393208537615 0.686077159574909 GO:0030742 GTP-dependent protein binding 7/5291 20/18639 0.35 1.23297108297108 0.33105227509216 0.714459462698894 GO:0004177 aminopeptidase activity 13/5291 40/18639 0.325 1.14490171990172 0.336278230734205 0.721185375297362 GO:0071949 FAD binding 13/5291 40/18639 0.325 1.14490171990172 0.336278230734205 0.721185375297362 GO:0033612 receptor serine/threonine kinase binding 10/5291 30/18639 0.333333333333333 1.17425817425817 0.336304061019495 0.721185375297362 GO:0048019 receptor antagonist activity 10/5291 30/18639 0.333333333333333 1.17425817425817 0.336304061019495 0.721185375297362 GO:0016504 peptidase activator activity 18/5291 57/18639 0.315789473684211 1.11245511245511 0.342467908651336 0.731522148488846 GO:0031491 nucleosome binding 23/5291 74/18639 0.310810810810811 1.09491640572722 0.344095670621198 0.731522148488846 GO:0004549 tRNA-specific ribonuclease activity 6/5291 17/18639 0.352941176470588 1.24333218450866 0.346212586399637 0.731522148488846 GO:0004550 nucleoside diphosphate kinase activity 6/5291 17/18639 0.352941176470588 1.24333218450866 0.346212586399637 0.731522148488846 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 6/5291 17/18639 0.352941176470588 1.24333218450866 0.346212586399637 0.731522148488846 GO:0008429 phosphatidylethanolamine binding 6/5291 17/18639 0.352941176470588 1.24333218450866 0.346212586399637 0.731522148488846 GO:0032977 membrane insertase activity 6/5291 17/18639 0.352941176470588 1.24333218450866 0.346212586399637 0.731522148488846 GO:0070403 NAD+ binding 6/5291 17/18639 0.352941176470588 1.24333218450866 0.346212586399637 0.731522148488846 GO:1901567 fatty acid derivative binding 6/5291 17/18639 0.352941176470588 1.24333218450866 0.346212586399637 0.731522148488846 GO:0061749 forked DNA-dependent helicase activity 15/5291 47/18639 0.319148936170213 1.12428974131102 0.346538989661629 0.731522148488846 GO:0004683 calcium/calmodulin-dependent protein kinase activity 9/5291 27/18639 0.333333333333333 1.17425817425817 0.350843614873484 0.739453547104645 GO:0044325 transmembrane transporter binding 41/5291 136/18639 0.301470588235294 1.06201290760114 0.354521217345694 0.74604075488167 GO:0005313 L-glutamate transmembrane transporter activity 5/5291 14/18639 0.357142857142857 1.25813375813376 0.363334035441048 0.75867740630735 GO:0008195 phosphatidate phosphatase activity 5/5291 14/18639 0.357142857142857 1.25813375813376 0.363334035441048 0.75867740630735 GO:0008559 ABC-type xenobiotic transporter activity 5/5291 14/18639 0.357142857142857 1.25813375813376 0.363334035441048 0.75867740630735 GO:0032036 myosin heavy chain binding 5/5291 14/18639 0.357142857142857 1.25813375813376 0.363334035441048 0.75867740630735 GO:0034236 protein kinase A catalytic subunit binding 5/5291 14/18639 0.357142857142857 1.25813375813376 0.363334035441048 0.75867740630735 GO:0050699 WW domain binding 8/5291 24/18639 0.333333333333333 1.17425817425817 0.366880228854625 0.763023773387215 GO:0070300 phosphatidic acid binding 8/5291 24/18639 0.333333333333333 1.17425817425817 0.366880228854625 0.763023773387215 GO:0005548 phospholipid transporter activity 21/5291 68/18639 0.308823529411765 1.08791566144507 0.367109883568978 0.763023773387215 GO:0005048 signal sequence binding 16/5291 51/18639 0.313725490196078 1.10518416400769 0.367777007034071 0.763236154382534 GO:0017116 single-stranded DNA helicase activity 18/5291 58/18639 0.310344827586207 1.09327485189554 0.374194665290499 0.775363485901019 GO:0070325 lipoprotein particle receptor binding 10/5291 31/18639 0.32258064516129 1.13637887831436 0.380144873110193 0.776111232690967 GO:0009378 four-way junction helicase activity 15/5291 48/18639 0.3125 1.10086703836704 0.381660629289091 0.776111232690967 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 4/5291 11/18639 0.363636363636364 1.28100891737255 0.383172607109456 0.776111232690967 GO:0003953 NAD+ nucleosidase activity 4/5291 11/18639 0.363636363636364 1.28100891737255 0.383172607109456 0.776111232690967 GO:0004016 adenylate cyclase activity 4/5291 11/18639 0.363636363636364 1.28100891737255 0.383172607109456 0.776111232690967 GO:0015217 ADP transmembrane transporter activity 4/5291 11/18639 0.363636363636364 1.28100891737255 0.383172607109456 0.776111232690967 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 4/5291 11/18639 0.363636363636364 1.28100891737255 0.383172607109456 0.776111232690967 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 4/5291 11/18639 0.363636363636364 1.28100891737255 0.383172607109456 0.776111232690967 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 4/5291 11/18639 0.363636363636364 1.28100891737255 0.383172607109456 0.776111232690967 GO:0019206 nucleoside kinase activity 4/5291 11/18639 0.363636363636364 1.28100891737255 0.383172607109456 0.776111232690967 GO:0035252 UDP-xylosyltransferase activity 4/5291 11/18639 0.363636363636364 1.28100891737255 0.383172607109456 0.776111232690967 GO:0042285 xylosyltransferase activity 4/5291 11/18639 0.363636363636364 1.28100891737255 0.383172607109456 0.776111232690967 GO:0048407 platelet-derived growth factor binding 4/5291 11/18639 0.363636363636364 1.28100891737255 0.383172607109456 0.776111232690967 GO:0050998 nitric-oxide synthase binding 4/5291 11/18639 0.363636363636364 1.28100891737255 0.383172607109456 0.776111232690967 GO:0070697 activin receptor binding 4/5291 11/18639 0.363636363636364 1.28100891737255 0.383172607109456 0.776111232690967 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 7/5291 21/18639 0.333333333333333 1.17425817425817 0.384793644838279 0.777064595181637 GO:1904047 S-adenosyl-L-methionine binding 7/5291 21/18639 0.333333333333333 1.17425817425817 0.384793644838279 0.777064595181637 GO:0016866 intramolecular transferase activity 9/5291 28/18639 0.321428571428571 1.13232038232038 0.397570978145291 0.801669241006401 GO:0005080 protein kinase C binding 16/5291 52/18639 0.307692307692308 1.08393062239216 0.401956937072742 0.807301250559209 GO:0000900 mRNA regulatory element binding translation repressor activity 6/5291 18/18639 0.333333333333333 1.17425817425817 0.405144521006028 0.807301250559209 GO:0008409 5'-3' exonuclease activity 6/5291 18/18639 0.333333333333333 1.17425817425817 0.405144521006028 0.807301250559209 GO:0008525 phosphatidylcholine transporter activity 6/5291 18/18639 0.333333333333333 1.17425817425817 0.405144521006028 0.807301250559209 GO:0015172 acidic amino acid transmembrane transporter activity 6/5291 18/18639 0.333333333333333 1.17425817425817 0.405144521006028 0.807301250559209 GO:0016854 racemase and epimerase activity 6/5291 18/18639 0.333333333333333 1.17425817425817 0.405144521006028 0.807301250559209 GO:0017075 syntaxin-1 binding 6/5291 18/18639 0.333333333333333 1.17425817425817 0.405144521006028 0.807301250559209 GO:0017128 phospholipid scramblase activity 6/5291 18/18639 0.333333333333333 1.17425817425817 0.405144521006028 0.807301250559209 GO:0005154 epidermal growth factor receptor binding 11/5291 35/18639 0.314285714285714 1.10715770715771 0.406180994713584 0.807301319268681 GO:0001786 phosphatidylserine binding 18/5291 59/18639 0.305084745762712 1.07474476966002 0.406339672170765 0.807301319268681 GO:0004521 RNA endonuclease activity 22/5291 73/18639 0.301369863013699 1.06165807535671 0.41295119955037 0.819232115407562 GO:0019706 protein-cysteine S-palmitoyltransferase activity 8/5291 25/18639 0.32 1.12728784728785 0.416916609751729 0.824676924999393 GO:0019707 protein-cysteine S-acyltransferase activity 8/5291 25/18639 0.32 1.12728784728785 0.416916609751729 0.824676924999393 GO:0022884 macromolecule transmembrane transporter activity 10/5291 32/18639 0.3125 1.10086703836704 0.424388457454939 0.837178465597994 GO:0097110 scaffold protein binding 21/5291 70/18639 0.3 1.05683235683236 0.426421656307049 0.837178465597994 GO:0002020 protease binding 40/5291 136/18639 0.294117647058824 1.03611015375721 0.427107621901259 0.837178465597994 GO:0019838 growth factor binding 40/5291 136/18639 0.294117647058824 1.03611015375721 0.427107621901259 0.837178465597994 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 5/5291 15/18639 0.333333333333333 1.17425817425817 0.428813840261889 0.837178465597994 GO:0031386 protein tag activity 5/5291 15/18639 0.333333333333333 1.17425817425817 0.428813840261889 0.837178465597994 GO:0033130 acetylcholine receptor binding 5/5291 15/18639 0.333333333333333 1.17425817425817 0.428813840261889 0.837178465597994 GO:0140776 protein-containing complex destabilizing activity 5/5291 15/18639 0.333333333333333 1.17425817425817 0.428813840261889 0.837178465597994 GO:0141047 molecular tag activity 5/5291 15/18639 0.333333333333333 1.17425817425817 0.428813840261889 0.837178465597994 GO:0030276 clathrin binding 14/5291 46/18639 0.304347826086957 1.07214876780094 0.433421003904388 0.844952058116635 GO:1901505 carbohydrate derivative transmembrane transporter activity 16/5291 53/18639 0.30188679245283 1.06347910121495 0.436360767548691 0.849457344320291 GO:0031683 G-protein beta/gamma-subunit complex binding 7/5291 22/18639 0.318181818181818 1.12088280270098 0.438678186350399 0.850293012567274 GO:0034062 5'-3' RNA polymerase activity 7/5291 22/18639 0.318181818181818 1.12088280270098 0.438678186350399 0.850293012567274 GO:0097747 RNA polymerase activity 7/5291 22/18639 0.318181818181818 1.12088280270098 0.438678186350399 0.850293012567274 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 20/5291 67/18639 0.298507462686567 1.05157448441031 0.440550313155601 0.852698385491714 GO:0001618 virus receptor activity 24/5291 81/18639 0.296296296296296 1.04378504378504 0.443353788362221 0.856896950039142 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 11/5291 36/18639 0.305555555555556 1.07640332640333 0.448189239453578 0.862540829774621 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 11/5291 36/18639 0.305555555555556 1.07640332640333 0.448189239453578 0.862540829774621 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 11/5291 36/18639 0.305555555555556 1.07640332640333 0.448189239453578 0.862540829774621 GO:0004859 phospholipase inhibitor activity 4/5291 12/18639 0.333333333333333 1.17425817425817 0.457308346786619 0.871401377304262 GO:0005165 neurotrophin receptor binding 4/5291 12/18639 0.333333333333333 1.17425817425817 0.457308346786619 0.871401377304262 GO:0005247 voltage-gated chloride channel activity 4/5291 12/18639 0.333333333333333 1.17425817425817 0.457308346786619 0.871401377304262 GO:0005527 macrolide binding 4/5291 12/18639 0.333333333333333 1.17425817425817 0.457308346786619 0.871401377304262 GO:0031543 peptidyl-proline dioxygenase activity 4/5291 12/18639 0.333333333333333 1.17425817425817 0.457308346786619 0.871401377304262 GO:0035251 UDP-glucosyltransferase activity 4/5291 12/18639 0.333333333333333 1.17425817425817 0.457308346786619 0.871401377304262 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 4/5291 12/18639 0.333333333333333 1.17425817425817 0.457308346786619 0.871401377304262 GO:0008157 protein phosphatase 1 binding 8/5291 26/18639 0.307692307692308 1.08393062239216 0.466687614979222 0.888021081460464 GO:0017069 snRNA binding 16/5291 54/18639 0.296296296296296 1.04378504378504 0.470726358989423 0.890351613469094 GO:0051287 NAD binding 16/5291 54/18639 0.296296296296296 1.04378504378504 0.470726358989423 0.890351613469094 GO:0004222 metalloendopeptidase activity 32/5291 110/18639 0.290909090909091 1.02480713389804 0.470778993337001 0.890351613469094 GO:0032934 sterol binding 20/5291 68/18639 0.294117647058824 1.03611015375721 0.471150492150027 0.890351613469094 GO:0140272 exogenous protein binding 24/5291 82/18639 0.292682926829268 1.03105595788523 0.471207552650187 0.890351613469094 GO:0005518 collagen binding 21/5291 72/18639 0.291666666666667 1.0274759024759 0.486056079855478 0.916970518570393 GO:0160215 deacylase activity 19/5291 65/18639 0.292307692307692 1.02973409127255 0.486733870001097 0.916970518570393 GO:0001968 fibronectin binding 9/5291 30/18639 0.3 1.05683235683236 0.490759508235663 0.916970518570393 GO:0031210 phosphatidylcholine binding 9/5291 30/18639 0.3 1.05683235683236 0.490759508235663 0.916970518570393 GO:0005158 insulin receptor binding 7/5291 23/18639 0.304347826086957 1.07214876780094 0.491740364143492 0.916970518570393 GO:0042171 lysophosphatidic acid acyltransferase activity 7/5291 23/18639 0.304347826086957 1.07214876780094 0.491740364143492 0.916970518570393 GO:0071617 lysophospholipid acyltransferase activity 7/5291 23/18639 0.304347826086957 1.07214876780094 0.491740364143492 0.916970518570393 GO:0005149 interleukin-1 receptor binding 5/5291 16/18639 0.3125 1.10086703836704 0.492761359350189 0.916970518570393 GO:0019841 retinol binding 5/5291 16/18639 0.3125 1.10086703836704 0.492761359350189 0.916970518570393 GO:0043023 ribosomal large subunit binding 5/5291 16/18639 0.3125 1.10086703836704 0.492761359350189 0.916970518570393 GO:0140327 flippase activity 5/5291 16/18639 0.3125 1.10086703836704 0.492761359350189 0.916970518570393 GO:0098632 cell-cell adhesion mediator activity 16/5291 55/18639 0.290909090909091 1.02480713389804 0.5048039169761 0.938088159332477 GO:0042169 SH2 domain binding 12/5291 41/18639 0.292682926829268 1.03105595788523 0.50908027871916 0.943439583744287 GO:0140318 protein transporter activity 12/5291 41/18639 0.292682926829268 1.03105595788523 0.50908027871916 0.943439583744287 GO:0008320 protein transmembrane transporter activity 8/5291 27/18639 0.296296296296296 1.04378504378504 0.515464036076375 0.952656515375079 GO:0035255 ionotropic glutamate receptor binding 8/5291 27/18639 0.296296296296296 1.04378504378504 0.515464036076375 0.952656515375079 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 6/5291 20/18639 0.3 1.05683235683236 0.52038256143142 0.959122565475919 GO:0031418 L-ascorbic acid binding 6/5291 20/18639 0.3 1.05683235683236 0.52038256143142 0.959122565475919 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 4/5291 13/18639 0.307692307692308 1.08393062239216 0.528099547179835 0.962837366045827 GO:0005035 death receptor activity 4/5291 13/18639 0.307692307692308 1.08393062239216 0.528099547179835 0.962837366045827 GO:0017154 semaphorin receptor activity 4/5291 13/18639 0.307692307692308 1.08393062239216 0.528099547179835 0.962837366045827 GO:0031432 titin binding 4/5291 13/18639 0.307692307692308 1.08393062239216 0.528099547179835 0.962837366045827 GO:0045159 myosin II binding 4/5291 13/18639 0.307692307692308 1.08393062239216 0.528099547179835 0.962837366045827 GO:0061459 L-arginine transmembrane transporter activity 4/5291 13/18639 0.307692307692308 1.08393062239216 0.528099547179835 0.962837366045827 GO:0140333 glycerophospholipid flippase activity 4/5291 13/18639 0.307692307692308 1.08393062239216 0.528099547179835 0.962837366045827 GO:0140410 monoatomic cation:bicarbonate symporter activity 4/5291 13/18639 0.307692307692308 1.08393062239216 0.528099547179835 0.962837366045827 GO:0043531 ADP binding 11/5291 38/18639 0.289473684210526 1.01975051975052 0.530727579153951 0.966324743176534 GO:0008327 methyl-CpG binding 9/5291 31/18639 0.290322580645161 1.02274099048293 0.536010949877901 0.973320958716457 GO:0072349 modified amino acid transmembrane transporter activity 9/5291 31/18639 0.290322580645161 1.02274099048293 0.536010949877901 0.973320958716457 GO:0015295 solute:proton symporter activity 7/5291 24/18639 0.291666666666667 1.0274759024759 0.543153361027143 0.984966698990162 GO:0016859 cis-trans isomerase activity 12/5291 42/18639 0.285714285714286 1.00650700650701 0.547743148051244 0.99039760665526 GO:0042056 chemoattractant activity 12/5291 42/18639 0.285714285714286 1.00650700650701 0.547743148051244 0.99039760665526 GO:0050840 extracellular matrix binding 19/5291 67/18639 0.283582089552239 0.99899576018979 0.548347453573749 0.99039760665526 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 5/5291 17/18639 0.294117647058824 1.03611015375721 0.553823348079586 0.993645874177318 GO:0008484 sulfuric ester hydrolase activity 5/5291 17/18639 0.294117647058824 1.03611015375721 0.553823348079586 0.993645874177318 GO:0017110 nucleoside diphosphate phosphatase activity 5/5291 17/18639 0.294117647058824 1.03611015375721 0.553823348079586 0.993645874177318 GO:0019198 transmembrane receptor protein phosphatase activity 5/5291 17/18639 0.294117647058824 1.03611015375721 0.553823348079586 0.993645874177318 GO:0048038 quinone binding 5/5291 17/18639 0.294117647058824 1.03611015375721 0.553823348079586 0.993645874177318 GO:0005246 calcium channel regulator activity 15/5291 53/18639 0.283018867924528 0.997011657389016 0.557421965903025 0.998775962778498 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 11/5291 39/18639 0.282051282051282 0.993603070526147 0.570461056989002 1 GO:0004445 inositol-polyphosphate 5-phosphatase activity 3/5291 10/18639 0.3 1.05683235683236 0.573105292944441 1 GO:0004955 prostaglandin receptor activity 3/5291 10/18639 0.3 1.05683235683236 0.573105292944441 1 GO:0005031 tumor necrosis factor receptor activity 3/5291 10/18639 0.3 1.05683235683236 0.573105292944441 1 GO:0005131 growth hormone receptor binding 3/5291 10/18639 0.3 1.05683235683236 0.573105292944441 1 GO:0008190 eukaryotic initiation factor 4E binding 3/5291 10/18639 0.3 1.05683235683236 0.573105292944441 1 GO:0015643 toxic substance binding 3/5291 10/18639 0.3 1.05683235683236 0.573105292944441 1 GO:0016868 intramolecular phosphotransferase activity 3/5291 10/18639 0.3 1.05683235683236 0.573105292944441 1 GO:0033204 ribonuclease P RNA binding 3/5291 10/18639 0.3 1.05683235683236 0.573105292944441 1 GO:0035256 G protein-coupled glutamate receptor binding 3/5291 10/18639 0.3 1.05683235683236 0.573105292944441 1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 3/5291 10/18639 0.3 1.05683235683236 0.573105292944441 1 GO:0051880 G-quadruplex DNA binding 3/5291 10/18639 0.3 1.05683235683236 0.573105292944441 1 GO:0070097 delta-catenin binding 3/5291 10/18639 0.3 1.05683235683236 0.573105292944441 1 GO:1905394 retromer complex binding 3/5291 10/18639 0.3 1.05683235683236 0.573105292944441 1 GO:1990763 arrestin family protein binding 3/5291 10/18639 0.3 1.05683235683236 0.573105292944441 1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 6/5291 21/18639 0.285714285714286 1.00650700650701 0.574618128068677 1 GO:0019200 carbohydrate kinase activity 6/5291 21/18639 0.285714285714286 1.00650700650701 0.574618128068677 1 GO:0016758 hexosyltransferase activity 55/5291 197/18639 0.279187817258883 0.983515729708623 0.585153168163536 1 GO:0008483 transaminase activity 7/5291 25/18639 0.28 0.986376866376866 0.592245430967582 1 GO:0004065 arylsulfatase activity 4/5291 14/18639 0.285714285714286 1.00650700650701 0.59400575187535 1 GO:0008474 palmitoyl-(protein) hydrolase activity 4/5291 14/18639 0.285714285714286 1.00650700650701 0.59400575187535 1 GO:0008494 translation activator activity 4/5291 14/18639 0.285714285714286 1.00650700650701 0.59400575187535 1 GO:0098599 palmitoyl hydrolase activity 4/5291 14/18639 0.285714285714286 1.00650700650701 0.59400575187535 1 GO:0019843 rRNA binding 18/5291 65/18639 0.276923076923077 0.975537560152945 0.596086384922927 1 GO:0099604 ligand-gated calcium channel activity 8/5291 29/18639 0.275862068965517 0.971799868351592 0.607649215507092 1 GO:0050997 quaternary ammonium group binding 11/5291 40/18639 0.275 0.968762993762994 0.608727180581424 1 GO:0042626 ATPase-coupled transmembrane transporter activity 27/5291 98/18639 0.275510204081633 0.970560327703185 0.610756257664781 1 GO:0003746 translation elongation factor activity 5/5291 18/18639 0.277777777777778 0.978548478548479 0.611007512338646 1 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 5/5291 18/18639 0.277777777777778 0.978548478548479 0.611007512338646 1 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 5/5291 18/18639 0.277777777777778 0.978548478548479 0.611007512338646 1 GO:0034185 apolipoprotein binding 5/5291 18/18639 0.277777777777778 0.978548478548479 0.611007512338646 1 GO:0035615 clathrin adaptor activity 5/5291 18/18639 0.277777777777778 0.978548478548479 0.611007512338646 1 GO:0030547 signaling receptor inhibitor activity 12/5291 44/18639 0.272727272727273 0.960756688029415 0.621353802323259 1 GO:0016782 transferase activity, transferring sulphur-containing groups 19/5291 70/18639 0.271428571428571 0.956181656181656 0.635678258843306 1 GO:0004112 cyclic-nucleotide phosphodiesterase activity 7/5291 26/18639 0.269230769230769 0.948439294593141 0.638503573700135 1 GO:0005112 Notch binding 7/5291 26/18639 0.269230769230769 0.948439294593141 0.638503573700135 1 GO:0120014 phospholipid transfer activity 7/5291 26/18639 0.269230769230769 0.948439294593141 0.638503573700135 1 GO:0004954 prostanoid receptor activity 3/5291 11/18639 0.272727272727273 0.960756688029415 0.64433005013256 1 GO:0005536 D-glucose binding 3/5291 11/18639 0.272727272727273 0.960756688029415 0.64433005013256 1 GO:0008526 phosphatidylinositol transfer activity 3/5291 11/18639 0.272727272727273 0.960756688029415 0.64433005013256 1 GO:0010854 adenylate cyclase regulator activity 3/5291 11/18639 0.272727272727273 0.960756688029415 0.64433005013256 1 GO:0015173 aromatic amino acid transmembrane transporter activity 3/5291 11/18639 0.272727272727273 0.960756688029415 0.64433005013256 1 GO:0019107 myristoyltransferase activity 3/5291 11/18639 0.272727272727273 0.960756688029415 0.64433005013256 1 GO:0019215 intermediate filament binding 3/5291 11/18639 0.272727272727273 0.960756688029415 0.64433005013256 1 GO:0034056 estrogen response element binding 3/5291 11/18639 0.272727272727273 0.960756688029415 0.64433005013256 1 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 3/5291 11/18639 0.272727272727273 0.960756688029415 0.64433005013256 1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 3/5291 11/18639 0.272727272727273 0.960756688029415 0.64433005013256 1 GO:0004812 aminoacyl-tRNA ligase activity 11/5291 41/18639 0.268292682926829 0.945134628061457 0.645264377930921 1 GO:0015175 neutral L-amino acid transmembrane transporter activity 11/5291 41/18639 0.268292682926829 0.945134628061457 0.645264377930921 1 GO:0016875 ligase activity, forming carbon-oxygen bonds 11/5291 41/18639 0.268292682926829 0.945134628061457 0.645264377930921 1 GO:0016877 ligase activity, forming carbon-sulfur bonds 11/5291 41/18639 0.268292682926829 0.945134628061457 0.645264377930921 1 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 8/5291 30/18639 0.266666666666667 0.939406539406539 0.650154563605794 1 GO:0004953 icosanoid receptor activity 4/5291 15/18639 0.266666666666667 0.939406539406539 0.654075537916609 1 GO:0005041 low-density lipoprotein particle receptor activity 4/5291 15/18639 0.266666666666667 0.939406539406539 0.654075537916609 1 GO:0015556 C4-dicarboxylate transmembrane transporter activity 4/5291 15/18639 0.266666666666667 0.939406539406539 0.654075537916609 1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 4/5291 15/18639 0.266666666666667 0.939406539406539 0.654075537916609 1 GO:0045504 dynein heavy chain binding 4/5291 15/18639 0.266666666666667 0.939406539406539 0.654075537916609 1 GO:0050700 CARD domain binding 4/5291 15/18639 0.266666666666667 0.939406539406539 0.654075537916609 1 GO:0055105 ubiquitin-protein transferase inhibitor activity 4/5291 15/18639 0.266666666666667 0.939406539406539 0.654075537916609 1 GO:0008376 acetylgalactosaminyltransferase activity 9/5291 34/18639 0.264705882352941 0.932499138381491 0.660818239626953 1 GO:0016831 carboxy-lyase activity 9/5291 34/18639 0.264705882352941 0.932499138381491 0.660818239626953 1 GO:0090482 vitamin transmembrane transporter activity 9/5291 34/18639 0.264705882352941 0.932499138381491 0.660818239626953 1 GO:0016918 retinal binding 5/5291 19/18639 0.263157894736842 0.927045927045927 0.663658954056148 1 GO:0097001 ceramide binding 5/5291 19/18639 0.263157894736842 0.927045927045927 0.663658954056148 1 GO:0035254 glutamate receptor binding 13/5291 49/18639 0.26530612244898 0.934613648899363 0.665652528626193 1 GO:0005212 structural constituent of eye lens 6/5291 23/18639 0.260869565217391 0.918984658115093 0.672838632825809 1 GO:0031681 G-protein beta-subunit binding 6/5291 23/18639 0.260869565217391 0.918984658115093 0.672838632825809 1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 6/5291 23/18639 0.260869565217391 0.918984658115093 0.672838632825809 1 GO:0005496 steroid binding 29/5291 108/18639 0.268518518518519 0.945930195930196 0.673432075019878 1 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 7/5291 27/18639 0.259259259259259 0.913311913311913 0.681567411868451 1 GO:0005126 cytokine receptor binding 75/5291 275/18639 0.272727272727273 0.960756688029415 0.681805532633725 1 GO:0120013 lipid transfer activity 17/5291 65/18639 0.261538461538462 0.921341029033337 0.699506308200464 1 GO:0050661 NADP binding 14/5291 54/18639 0.259259259259259 0.913311913311913 0.70429779070447 1 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 10/5291 39/18639 0.256410256410256 0.903275518660134 0.705236648509367 1 GO:0003995 acyl-CoA dehydrogenase activity 3/5291 12/18639 0.25 0.880693630693631 0.706670617914541 1 GO:0004526 ribonuclease P activity 3/5291 12/18639 0.25 0.880693630693631 0.706670617914541 1 GO:0008603 cAMP-dependent protein kinase regulator activity 3/5291 12/18639 0.25 0.880693630693631 0.706670617914541 1 GO:0010853 cyclase activator activity 3/5291 12/18639 0.25 0.880693630693631 0.706670617914541 1 GO:0016273 arginine N-methyltransferase activity 3/5291 12/18639 0.25 0.880693630693631 0.706670617914541 1 GO:0016274 protein-arginine N-methyltransferase activity 3/5291 12/18639 0.25 0.880693630693631 0.706670617914541 1 GO:0016423 tRNA (guanine) methyltransferase activity 3/5291 12/18639 0.25 0.880693630693631 0.706670617914541 1 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 3/5291 12/18639 0.25 0.880693630693631 0.706670617914541 1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 3/5291 12/18639 0.25 0.880693630693631 0.706670617914541 1 GO:0017070 U6 snRNA binding 4/5291 16/18639 0.25 0.880693630693631 0.707846930772083 1 GO:0055102 lipase inhibitor activity 4/5291 16/18639 0.25 0.880693630693631 0.707846930772083 1 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 4/5291 16/18639 0.25 0.880693630693631 0.707846930772083 1 GO:0001972 retinoic acid binding 5/5291 20/18639 0.25 0.880693630693631 0.711417751597724 1 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 6/5291 24/18639 0.25 0.880693630693631 0.716067056758698 1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 6/5291 24/18639 0.25 0.880693630693631 0.716067056758698 1 GO:0004622 lysophospholipase activity 6/5291 24/18639 0.25 0.880693630693631 0.716067056758698 1 GO:0030552 cAMP binding 6/5291 24/18639 0.25 0.880693630693631 0.716067056758698 1 GO:0015179 L-amino acid transmembrane transporter activity 16/5291 62/18639 0.258064516129032 0.90910310265149 0.71855544634203 1 GO:0045499 chemorepellent activity 7/5291 28/18639 0.25 0.880693630693631 0.721216129408332 1 GO:0050698 proteoglycan sulfotransferase activity 7/5291 28/18639 0.25 0.880693630693631 0.721216129408332 1 GO:0016597 amino acid binding 13/5291 51/18639 0.254901960784314 0.897962133256251 0.725777600318243 1 GO:0008378 galactosyltransferase activity 8/5291 32/18639 0.25 0.880693630693631 0.726579148000395 1 GO:0015101 organic cation transmembrane transporter activity 21/5291 81/18639 0.259259259259259 0.913311913311913 0.72716366675428 1 GO:0008237 metallopeptidase activity 49/5291 184/18639 0.266304347826087 0.938130171825824 0.72764649270745 1 GO:0045505 dynein intermediate chain binding 9/5291 36/18639 0.25 0.880693630693631 0.732004135068424 1 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 48/5291 181/18639 0.265193370165746 0.934216448028603 0.737509165614346 1 GO:0016248 channel inhibitor activity 11/5291 44/18639 0.25 0.880693630693631 0.742737884208264 1 GO:0030020 extracellular matrix structural constituent conferring tensile strength 11/5291 44/18639 0.25 0.880693630693631 0.742737884208264 1 GO:0008373 sialyltransferase activity 5/5291 21/18639 0.238095238095238 0.838755838755839 0.754167633950551 1 GO:0070182 DNA polymerase binding 5/5291 21/18639 0.238095238095238 0.838755838755839 0.754167633950551 1 GO:0015662 P-type ion transporter activity 6/5291 25/18639 0.24 0.845465885465885 0.755168622797998 1 GO:0140358 P-type transmembrane transporter activity 6/5291 25/18639 0.24 0.845465885465885 0.755168622797998 1 GO:0016805 dipeptidase activity 4/5291 17/18639 0.235294117647059 0.82888812300577 0.755238802369774 1 GO:0031489 myosin V binding 4/5291 17/18639 0.235294117647059 0.82888812300577 0.755238802369774 1 GO:0045125 bioactive lipid receptor activity 4/5291 17/18639 0.235294117647059 0.82888812300577 0.755238802369774 1 GO:0070402 NADPH binding 4/5291 17/18639 0.235294117647059 0.82888812300577 0.755238802369774 1 GO:0005416 amino acid:monoatomic cation symporter activity 7/5291 29/18639 0.241379310344828 0.850324884807644 0.757351056558727 1 GO:0035250 UDP-galactosyltransferase activity 7/5291 29/18639 0.241379310344828 0.850324884807644 0.757351056558727 1 GO:0043236 laminin binding 7/5291 29/18639 0.241379310344828 0.850324884807644 0.757351056558727 1 GO:0003774 cytoskeletal motor activity 40/5291 153/18639 0.261437908496732 0.920986803339744 0.758445899866036 1 GO:0002161 aminoacyl-tRNA editing activity 3/5291 13/18639 0.230769230769231 0.812947966794121 0.760241939134953 1 GO:0008417 fucosyltransferase activity 3/5291 13/18639 0.230769230769231 0.812947966794121 0.760241939134953 1 GO:0015651 quaternary ammonium group transmembrane transporter activity 3/5291 13/18639 0.230769230769231 0.812947966794121 0.760241939134953 1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 3/5291 13/18639 0.230769230769231 0.812947966794121 0.760241939134953 1 GO:0019104 DNA N-glycosylase activity 3/5291 13/18639 0.230769230769231 0.812947966794121 0.760241939134953 1 GO:0019855 calcium channel inhibitor activity 3/5291 13/18639 0.230769230769231 0.812947966794121 0.760241939134953 1 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 3/5291 13/18639 0.230769230769231 0.812947966794121 0.760241939134953 1 GO:0071837 HMG box domain binding 3/5291 13/18639 0.230769230769231 0.812947966794121 0.760241939134953 1 GO:0141110 transporter inhibitor activity 11/5291 45/18639 0.244444444444444 0.861122661122661 0.770858219455384 1 GO:0008146 sulfotransferase activity 13/5291 53/18639 0.245283018867925 0.864076769737147 0.778513103943333 1 GO:0015026 coreceptor activity 15/5291 61/18639 0.245901639344262 0.866256030190456 0.786184249648558 1 GO:0038024 cargo receptor activity 16/5291 65/18639 0.246153846153846 0.867144497913729 0.789972483470996 1 GO:0016769 transferase activity, transferring nitrogenous groups 7/5291 30/18639 0.233333333333333 0.821980721980722 0.789976076153097 1 GO:0098918 structural constituent of synapse 7/5291 30/18639 0.233333333333333 0.821980721980722 0.789976076153097 1 GO:0030247 polysaccharide binding 6/5291 26/18639 0.230769230769231 0.812947966794121 0.790168137527357 1 GO:0005516 calmodulin binding 54/5291 207/18639 0.260869565217391 0.918984658115093 0.791531581268739 1 GO:0016881 acid-amino acid ligase activity 5/5291 22/18639 0.227272727272727 0.800630573357846 0.791982936226292 1 GO:0008307 structural constituent of muscle 10/5291 42/18639 0.238095238095238 0.838755838755839 0.794398802567976 1 GO:0030228 lipoprotein particle receptor activity 4/5291 18/18639 0.222222222222222 0.782838782838783 0.796447742378668 1 GO:0050811 GABA receptor binding 4/5291 18/18639 0.222222222222222 0.782838782838783 0.796447742378668 1 GO:0008331 high voltage-gated calcium channel activity 3/5291 14/18639 0.214285714285714 0.754880254880255 0.805579081114845 1 GO:0015926 glucosidase activity 3/5291 14/18639 0.214285714285714 0.754880254880255 0.805579081114845 1 GO:0016530 metallochaperone activity 3/5291 14/18639 0.214285714285714 0.754880254880255 0.805579081114845 1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 3/5291 14/18639 0.214285714285714 0.754880254880255 0.805579081114845 1 GO:0044548 S100 protein binding 3/5291 14/18639 0.214285714285714 0.754880254880255 0.805579081114845 1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 3/5291 14/18639 0.214285714285714 0.754880254880255 0.805579081114845 1 GO:1901474 azole transmembrane transporter activity 3/5291 14/18639 0.214285714285714 0.754880254880255 0.805579081114845 1 GO:1901612 cardiolipin binding 3/5291 14/18639 0.214285714285714 0.754880254880255 0.805579081114845 1 GO:1990825 sequence-specific mRNA binding 3/5291 14/18639 0.214285714285714 0.754880254880255 0.805579081114845 1 GO:0008235 metalloexopeptidase activity 16/5291 66/18639 0.242424242424242 0.854005944915036 0.810700118486356 1 GO:0005245 voltage-gated calcium channel activity 10/5291 43/18639 0.232558139534884 0.819249889017331 0.819249390092511 1 GO:0008200 ion channel inhibitor activity 10/5291 43/18639 0.232558139534884 0.819249889017331 0.819249390092511 1 GO:0005044 scavenger receptor activity 6/5291 27/18639 0.222222222222222 0.782838782838783 0.821196916287044 1 GO:0005104 fibroblast growth factor receptor binding 6/5291 27/18639 0.222222222222222 0.782838782838783 0.821196916287044 1 GO:0000182 rDNA binding 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0001094 TFIID-class transcription factor complex binding 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0004935 adrenergic receptor activity 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0008239 dipeptidyl-peptidase activity 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0008401 retinoic acid 4-hydroxylase activity 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0015187 glycine transmembrane transporter activity 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0015203 polyamine transmembrane transporter activity 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0019911 structural constituent of myelin sheath 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0035374 chondroitin sulfate binding 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0042975 peroxisome proliferator activated receptor binding 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0047429 nucleoside triphosphate diphosphatase activity 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0070739 protein-glutamic acid ligase activity 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0070740 tubulin-glutamic acid ligase activity 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0140135 mechanosensitive monoatomic cation channel activity 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0141109 transporter activator activity 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:1990757 ubiquitin ligase activator activity 2/5291 10/18639 0.2 0.704554904554905 0.823974266598719 1 GO:0005283 amino acid:sodium symporter activity 5/5291 23/18639 0.217391304347826 0.765820548429244 0.825078576059759 1 GO:0043274 phospholipase binding 5/5291 23/18639 0.217391304347826 0.765820548429244 0.825078576059759 1 GO:0099186 structural constituent of postsynapse 5/5291 23/18639 0.217391304347826 0.765820548429244 0.825078576059759 1 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 4/5291 19/18639 0.210526315789474 0.741636741636742 0.83185808593134 1 GO:0030506 ankyrin binding 4/5291 19/18639 0.210526315789474 0.741636741636742 0.83185808593134 1 GO:0031420 alkali metal ion binding 4/5291 19/18639 0.210526315789474 0.741636741636742 0.83185808593134 1 GO:0008238 exopeptidase activity 25/5291 102/18639 0.245098039215686 0.86342512813101 0.836599298336439 1 GO:0001540 amyloid-beta binding 20/5291 83/18639 0.240963855421687 0.848861330789042 0.839126705574213 1 GO:0008081 phosphoric diester hydrolase activity 21/5291 87/18639 0.241379310344828 0.850324884807644 0.841482790106987 1 GO:0004190 aspartic-type endopeptidase activity 8/5291 36/18639 0.222222222222222 0.782838782838783 0.843099902333249 1 GO:0005319 lipid transporter activity 45/5291 178/18639 0.252808988764045 0.890589064746368 0.843115155367543 1 GO:0004089 carbonate dehydratase activity 3/5291 15/18639 0.2 0.704554904554905 0.843454966914404 1 GO:0005402 carbohydrate:monoatomic cation symporter activity 3/5291 15/18639 0.2 0.704554904554905 0.843454966914404 1 GO:0008242 omega peptidase activity 3/5291 15/18639 0.2 0.704554904554905 0.843454966914404 1 GO:0010181 FMN binding 3/5291 15/18639 0.2 0.704554904554905 0.843454966914404 1 GO:0017081 chloride channel regulator activity 3/5291 15/18639 0.2 0.704554904554905 0.843454966914404 1 GO:0034483 heparan sulfate sulfotransferase activity 3/5291 15/18639 0.2 0.704554904554905 0.843454966914404 1 GO:0047372 monoacylglycerol lipase activity 3/5291 15/18639 0.2 0.704554904554905 0.843454966914404 1 GO:0019212 phosphatase inhibitor activity 13/5291 56/18639 0.232142857142857 0.817786942786943 0.843546515372627 1 GO:0030515 snoRNA binding 7/5291 32/18639 0.21875 0.770606926856927 0.845105120154936 1 GO:0042910 xenobiotic transmembrane transporter activity 7/5291 32/18639 0.21875 0.770606926856927 0.845105120154936 1 GO:0120015 sterol transfer activity 7/5291 32/18639 0.21875 0.770606926856927 0.845105120154936 1 GO:0046875 ephrin receptor binding 6/5291 28/18639 0.214285714285714 0.754880254880255 0.848464403617602 1 GO:0051959 dynein light intermediate chain binding 6/5291 28/18639 0.214285714285714 0.754880254880255 0.848464403617602 1 GO:0005315 phosphate transmembrane transporter activity 5/5291 24/18639 0.208333333333333 0.733911358911359 0.853765817981091 1 GO:0015149 hexose transmembrane transporter activity 5/5291 24/18639 0.208333333333333 0.733911358911359 0.853765817981091 1 GO:0030215 semaphorin receptor binding 5/5291 24/18639 0.208333333333333 0.733911358911359 0.853765817981091 1 GO:0055056 D-glucose transmembrane transporter activity 5/5291 24/18639 0.208333333333333 0.733911358911359 0.853765817981091 1 GO:0070840 dynein complex binding 5/5291 24/18639 0.208333333333333 0.733911358911359 0.853765817981091 1 GO:0051015 actin filament binding 53/5291 209/18639 0.253588516746411 0.893335166062439 0.854273866889401 1 GO:0004857 enzyme inhibitor activity 109/5291 416/18639 0.262019230769231 0.923034670630824 0.854404764165759 1 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 32/5291 130/18639 0.246153846153846 0.867144497913729 0.854658489600225 1 GO:0004864 protein phosphatase inhibitor activity 12/5291 53/18639 0.226415094339623 0.797609325911213 0.861362107838877 1 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 4/5291 20/18639 0.2 0.704554904554905 0.861968169514744 1 GO:0010851 cyclase regulator activity 4/5291 20/18639 0.2 0.704554904554905 0.861968169514744 1 GO:0016408 C-acyltransferase activity 4/5291 20/18639 0.2 0.704554904554905 0.861968169514744 1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 4/5291 20/18639 0.2 0.704554904554905 0.861968169514744 1 GO:0000099 sulfur amino acid transmembrane transporter activity 2/5291 11/18639 0.181818181818182 0.640504458686277 0.863895203591199 1 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/5291 11/18639 0.181818181818182 0.640504458686277 0.863895203591199 1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 2/5291 11/18639 0.181818181818182 0.640504458686277 0.863895203591199 1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/5291 11/18639 0.181818181818182 0.640504458686277 0.863895203591199 1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 2/5291 11/18639 0.181818181818182 0.640504458686277 0.863895203591199 1 GO:0032794 GTPase activating protein binding 2/5291 11/18639 0.181818181818182 0.640504458686277 0.863895203591199 1 GO:0034511 U3 snoRNA binding 2/5291 11/18639 0.181818181818182 0.640504458686277 0.863895203591199 1 GO:0099528 G protein-coupled neurotransmitter receptor activity 2/5291 11/18639 0.181818181818182 0.640504458686277 0.863895203591199 1 GO:1990948 ubiquitin ligase inhibitor activity 2/5291 11/18639 0.181818181818182 0.640504458686277 0.863895203591199 1 GO:0030551 cyclic nucleotide binding 8/5291 37/18639 0.216216216216216 0.761680977897194 0.865043646964241 1 GO:0043394 proteoglycan binding 8/5291 37/18639 0.216216216216216 0.761680977897194 0.865043646964241 1 GO:0070001 aspartic-type peptidase activity 8/5291 37/18639 0.216216216216216 0.761680977897194 0.865043646964241 1 GO:0030296 protein tyrosine kinase activator activity 7/5291 33/18639 0.212121212121212 0.747255201800656 0.867953946049873 1 GO:0015562 efflux transmembrane transporter activity 3/5291 16/18639 0.1875 0.660520223020223 0.874749129101093 1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 3/5291 16/18639 0.1875 0.660520223020223 0.874749129101093 1 GO:0015485 cholesterol binding 12/5291 54/18639 0.222222222222222 0.782838782838783 0.878309913327463 1 GO:0047617 fatty acyl-CoA hydrolase activity 5/5291 25/18639 0.2 0.704554904554905 0.878415116776864 1 GO:0120020 cholesterol transfer activity 5/5291 25/18639 0.2 0.704554904554905 0.878415116776864 1 GO:0031492 nucleosomal DNA binding 9/5291 42/18639 0.214285714285714 0.754880254880255 0.881893383445251 1 GO:0042887 amide transmembrane transporter activity 8/5291 38/18639 0.210526315789474 0.741636741636742 0.884421389833084 1 GO:0015174 basic amino acid transmembrane transporter activity 4/5291 21/18639 0.19047619047619 0.671004671004671 0.887333001412201 1 GO:0099106 ion channel regulator activity 39/5291 160/18639 0.24375 0.85867628992629 0.889765705239985 1 GO:1901682 sulfur compound transmembrane transporter activity 14/5291 63/18639 0.222222222222222 0.782838782838783 0.892412467191365 1 GO:0005201 extracellular matrix structural constituent 41/5291 168/18639 0.244047619047619 0.859724734724735 0.893092269560123 1 GO:0008374 O-acyltransferase activity 12/5291 55/18639 0.218181818181818 0.768605350423532 0.893547764546414 1 GO:0072341 modified amino acid binding 21/5291 91/18639 0.230769230769231 0.812947966794121 0.894982820924081 1 GO:0003720 telomerase activity 2/5291 12/18639 0.166666666666667 0.587129087129087 0.895340120726531 1 GO:0004000 adenosine deaminase activity 2/5291 12/18639 0.166666666666667 0.587129087129087 0.895340120726531 1 GO:0005436 sodium:phosphate symporter activity 2/5291 12/18639 0.166666666666667 0.587129087129087 0.895340120726531 1 GO:0015166 polyol transmembrane transporter activity 2/5291 12/18639 0.166666666666667 0.587129087129087 0.895340120726531 1 GO:0015269 calcium-activated potassium channel activity 2/5291 12/18639 0.166666666666667 0.587129087129087 0.895340120726531 1 GO:0015368 calcium:monoatomic cation antiporter activity 2/5291 12/18639 0.166666666666667 0.587129087129087 0.895340120726531 1 GO:0016208 AMP binding 2/5291 12/18639 0.166666666666667 0.587129087129087 0.895340120726531 1 GO:0016801 hydrolase activity, acting on ether bonds 2/5291 12/18639 0.166666666666667 0.587129087129087 0.895340120726531 1 GO:0016803 ether hydrolase activity 2/5291 12/18639 0.166666666666667 0.587129087129087 0.895340120726531 1 GO:0016840 carbon-nitrogen lyase activity 2/5291 12/18639 0.166666666666667 0.587129087129087 0.895340120726531 1 GO:0036009 protein-glutamine N-methyltransferase activity 2/5291 12/18639 0.166666666666667 0.587129087129087 0.895340120726531 1 GO:0042301 phosphate ion binding 2/5291 12/18639 0.166666666666667 0.587129087129087 0.895340120726531 1 GO:0070679 inositol 1,4,5 trisphosphate binding 2/5291 12/18639 0.166666666666667 0.587129087129087 0.895340120726531 1 GO:0097371 MDM2/MDM4 family protein binding 2/5291 12/18639 0.166666666666667 0.587129087129087 0.895340120726531 1 GO:1990459 transferrin receptor binding 2/5291 12/18639 0.166666666666667 0.587129087129087 0.895340120726531 1 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 9/5291 43/18639 0.209302325581395 0.737324900115598 0.8984756169798 1 GO:0005178 integrin binding 39/5291 161/18639 0.242236024844721 0.853342896821158 0.898479869473547 1 GO:0005227 calcium-activated cation channel activity 5/5291 26/18639 0.192307692307692 0.677456638995101 0.899426302312461 1 GO:0015145 monosaccharide transmembrane transporter activity 5/5291 26/18639 0.192307692307692 0.677456638995101 0.899426302312461 1 GO:0016289 acyl-CoA hydrolase activity 5/5291 26/18639 0.192307692307692 0.677456638995101 0.899426302312461 1 GO:0051139 metal cation:proton antiporter activity 5/5291 26/18639 0.192307692307692 0.677456638995101 0.899426302312461 1 GO:0030169 low-density lipoprotein particle binding 3/5291 17/18639 0.176470588235294 0.621666092254328 0.900358484829233 1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 3/5291 17/18639 0.176470588235294 0.621666092254328 0.900358484829233 1 GO:1901681 sulfur compound binding 69/5291 275/18639 0.250909090909091 0.883896152987062 0.902422464903663 1 GO:0043178 alcohol binding 21/5291 92/18639 0.228260869565217 0.804111575850706 0.905811923488182 1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 13/5291 60/18639 0.216666666666667 0.763267813267813 0.906119951028666 1 GO:0030170 pyridoxal phosphate binding 12/5291 56/18639 0.214285714285714 0.754880254880255 0.907184468866537 1 GO:0030021 extracellular matrix structural constituent conferring compression resistance 4/5291 22/18639 0.181818181818182 0.640504458686277 0.908521904786848 1 GO:0061133 endopeptidase activator activity 4/5291 22/18639 0.181818181818182 0.640504458686277 0.908521904786848 1 GO:0016411 acylglycerol O-acyltransferase activity 6/5291 31/18639 0.193548387096774 0.681827326988617 0.910466110511514 1 GO:0016878 acid-thiol ligase activity 6/5291 31/18639 0.193548387096774 0.681827326988617 0.910466110511514 1 GO:0016790 thiolester hydrolase activity 9/5291 44/18639 0.204545454545455 0.720567516022061 0.913061490843606 1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 13/5291 61/18639 0.213114754098361 0.750755226165062 0.918022834757762 1 GO:0070279 vitamin B6 binding 12/5291 57/18639 0.210526315789474 0.741636741636742 0.91933377139441 1 GO:0003964 RNA-directed DNA polymerase activity 2/5291 13/18639 0.153846153846154 0.54196531119608 0.919903426470454 1 GO:0008035 high-density lipoprotein particle binding 2/5291 13/18639 0.153846153846154 0.54196531119608 0.919903426470454 1 GO:0008253 5'-nucleotidase activity 2/5291 13/18639 0.153846153846154 0.54196531119608 0.919903426470454 1 GO:0030955 potassium ion binding 2/5291 13/18639 0.153846153846154 0.54196531119608 0.919903426470454 1 GO:0035325 Toll-like receptor binding 2/5291 13/18639 0.153846153846154 0.54196531119608 0.919903426470454 1 GO:0035673 oligopeptide transmembrane transporter activity 2/5291 13/18639 0.153846153846154 0.54196531119608 0.919903426470454 1 GO:0071714 icosanoid transmembrane transporter activity 2/5291 13/18639 0.153846153846154 0.54196531119608 0.919903426470454 1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/5291 13/18639 0.153846153846154 0.54196531119608 0.919903426470454 1 GO:1901338 catecholamine binding 2/5291 13/18639 0.153846153846154 0.54196531119608 0.919903426470454 1 GO:0005544 calcium-dependent phospholipid binding 11/5291 53/18639 0.207547169811321 0.731141882085278 0.921019667083358 1 GO:0017046 peptide hormone binding 11/5291 53/18639 0.207547169811321 0.731141882085278 0.921019667083358 1 GO:0015280 ligand-gated sodium channel activity 3/5291 18/18639 0.166666666666667 0.587129087129087 0.921140633319346 1 GO:1901611 phosphatidylglycerol binding 3/5291 18/18639 0.166666666666667 0.587129087129087 0.921140633319346 1 GO:0016247 channel regulator activity 40/5291 168/18639 0.238095238095238 0.838755838755839 0.922386515716667 1 GO:0003779 actin binding 113/5291 443/18639 0.255079006772009 0.898585826351063 0.922394000950668 1 GO:0042562 hormone binding 21/5291 94/18639 0.223404255319149 0.787002818917713 0.924750768814451 1 GO:0071813 lipoprotein particle binding 6/5291 32/18639 0.1875 0.660520223020223 0.925549415978417 1 GO:0071814 protein-lipid complex binding 6/5291 32/18639 0.1875 0.660520223020223 0.925549415978417 1 GO:0004022 alcohol dehydrogenase (NAD+) activity 4/5291 23/18639 0.173913043478261 0.612656438743395 0.926088921360972 1 GO:0140103 catalytic activity, acting on a glycoprotein 4/5291 23/18639 0.173913043478261 0.612656438743395 0.926088921360972 1 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 11/5291 54/18639 0.203703703703704 0.717602217602218 0.931945418044168 1 GO:0005242 inward rectifier potassium channel activity 5/5291 28/18639 0.178571428571429 0.629066879066879 0.932149470099008 1 GO:0046625 sphingolipid binding 5/5291 28/18639 0.178571428571429 0.629066879066879 0.932149470099008 1 GO:0051119 sugar transmembrane transporter activity 5/5291 28/18639 0.178571428571429 0.629066879066879 0.932149470099008 1 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 20/5291 91/18639 0.21978021978022 0.774236158851544 0.933089099497208 1 GO:0008083 growth factor activity 38/5291 162/18639 0.234567901234568 0.826329826329826 0.933497737998253 1 GO:0015399 primary active transmembrane transporter activity 39/5291 166/18639 0.234939759036145 0.827639797519316 0.934214201256398 1 GO:0141108 transporter regulator activity 40/5291 170/18639 0.235294117647059 0.82888812300577 0.934936510509624 1 GO:0015297 antiporter activity 31/5291 135/18639 0.22962962962963 0.808933408933409 0.935518090360304 1 GO:0015085 calcium ion transmembrane transporter activity 34/5291 147/18639 0.231292517006803 0.814791386219958 0.937049085115876 1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 3/5291 19/18639 0.157894736842105 0.556227556227556 0.937881110954597 1 GO:0005229 intracellularly calcium-gated chloride channel activity 3/5291 19/18639 0.157894736842105 0.556227556227556 0.937881110954597 1 GO:0008381 mechanosensitive monoatomic ion channel activity 3/5291 19/18639 0.157894736842105 0.556227556227556 0.937881110954597 1 GO:0022840 leak channel activity 3/5291 19/18639 0.157894736842105 0.556227556227556 0.937881110954597 1 GO:0022842 narrow pore channel activity 3/5291 19/18639 0.157894736842105 0.556227556227556 0.937881110954597 1 GO:0042834 peptidoglycan binding 3/5291 19/18639 0.157894736842105 0.556227556227556 0.937881110954597 1 GO:0043395 heparan sulfate proteoglycan binding 3/5291 19/18639 0.157894736842105 0.556227556227556 0.937881110954597 1 GO:0046624 sphingolipid transporter activity 3/5291 19/18639 0.157894736842105 0.556227556227556 0.937881110954597 1 GO:0070003 threonine-type peptidase activity 3/5291 19/18639 0.157894736842105 0.556227556227556 0.937881110954597 1 GO:0141147 intracellularly calcium-gated channel activity 3/5291 19/18639 0.157894736842105 0.556227556227556 0.937881110954597 1 GO:0019239 deaminase activity 6/5291 33/18639 0.181818181818182 0.640504458686277 0.938348409295871 1 GO:0019956 chemokine binding 6/5291 33/18639 0.181818181818182 0.640504458686277 0.938348409295871 1 GO:0015386 potassium:proton antiporter activity 2/5291 14/18639 0.142857142857143 0.503253503253503 0.938957484029722 1 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 2/5291 14/18639 0.142857142857143 0.503253503253503 0.938957484029722 1 GO:0043176 amine binding 2/5291 14/18639 0.142857142857143 0.503253503253503 0.938957484029722 1 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 2/5291 14/18639 0.142857142857143 0.503253503253503 0.938957484029722 1 GO:0015459 potassium channel regulator activity 12/5291 59/18639 0.203389830508475 0.716496513106683 0.939632915878505 1 GO:0046982 protein heterodimerization activity 92/5291 369/18639 0.249322493224932 0.878306927087415 0.940275803603075 1 GO:0019955 cytokine binding 33/5291 144/18639 0.229166666666667 0.807302494802495 0.942466856918283 1 GO:0000146 microfilament motor activity 7/5291 38/18639 0.184210526315789 0.648932148932149 0.944290291825926 1 GO:0005501 retinoid binding 7/5291 38/18639 0.184210526315789 0.648932148932149 0.944290291825926 1 GO:0019840 isoprenoid binding 7/5291 38/18639 0.184210526315789 0.648932148932149 0.944290291825926 1 GO:0003777 microtubule motor activity 14/5291 68/18639 0.205882352941176 0.725277107630049 0.94499879094036 1 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 6/5291 34/18639 0.176470588235294 0.621666092254328 0.949148204809991 1 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 6/5291 34/18639 0.176470588235294 0.621666092254328 0.949148204809991 1 GO:0051427 hormone receptor binding 6/5291 34/18639 0.176470588235294 0.621666092254328 0.949148204809991 1 GO:0008375 acetylglucosaminyltransferase activity 8/5291 43/18639 0.186046511627907 0.655399911213865 0.94981745123521 1 GO:0042288 MHC class I protein binding 3/5291 20/18639 0.15 0.528416178416178 0.95127751238516 1 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 27/5291 122/18639 0.221311475409836 0.779630427171411 0.952208316544838 1 GO:0016798 hydrolase activity, acting on glycosyl bonds 29/5291 130/18639 0.223076923076923 0.785849701234317 0.952315827274916 1 GO:0005251 delayed rectifier potassium channel activity 4/5291 25/18639 0.16 0.563643923643924 0.952389432562678 1 GO:0004129 cytochrome-c oxidase activity 2/5291 15/18639 0.133333333333333 0.46970326970327 0.95365017897054 1 GO:0005523 tropomyosin binding 2/5291 15/18639 0.133333333333333 0.46970326970327 0.95365017897054 1 GO:0008252 nucleotidase activity 2/5291 15/18639 0.133333333333333 0.46970326970327 0.95365017897054 1 GO:0015929 hexosaminidase activity 2/5291 15/18639 0.133333333333333 0.46970326970327 0.95365017897054 1 GO:0016846 carbon-sulfur lyase activity 2/5291 15/18639 0.133333333333333 0.46970326970327 0.95365017897054 1 GO:0030553 cGMP binding 2/5291 15/18639 0.133333333333333 0.46970326970327 0.95365017897054 1 GO:0048531 beta-1,3-galactosyltransferase activity 2/5291 15/18639 0.133333333333333 0.46970326970327 0.95365017897054 1 GO:0001965 G-protein alpha-subunit binding 5/5291 30/18639 0.166666666666667 0.587129087129087 0.95499898402604 1 GO:0022839 monoatomic ion-gated channel activity 5/5291 30/18639 0.166666666666667 0.587129087129087 0.95499898402604 1 GO:0005262 calcium channel activity 29/5291 131/18639 0.221374045801527 0.779850848553139 0.95722234591198 1 GO:0003954 NADH dehydrogenase activity 8/5291 44/18639 0.181818181818182 0.640504458686277 0.957985442433343 1 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 7/5291 40/18639 0.175 0.616485541485541 0.961599213629889 1 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 29/5291 132/18639 0.21969696969697 0.773942887579251 0.961688490548736 1 GO:0001846 opsonin binding 3/5291 21/18639 0.142857142857143 0.503253503253503 0.961934930880653 1 GO:0005248 voltage-gated sodium channel activity 3/5291 21/18639 0.142857142857143 0.503253503253503 0.961934930880653 1 GO:0036122 BMP binding 3/5291 21/18639 0.142857142857143 0.503253503253503 0.961934930880653 1 GO:0051428 peptide hormone receptor binding 3/5291 21/18639 0.142857142857143 0.503253503253503 0.961934930880653 1 GO:0061891 calcium ion sensor activity 3/5291 21/18639 0.142857142857143 0.503253503253503 0.961934930880653 1 GO:0004435 phosphatidylinositol phospholipase C activity 4/5291 26/18639 0.153846153846154 0.54196531119608 0.962019092608173 1 GO:0030507 spectrin binding 4/5291 26/18639 0.153846153846154 0.54196531119608 0.962019092608173 1 GO:0009055 electron transfer activity 25/5291 116/18639 0.21551724137931 0.759218647149682 0.962192866770303 1 GO:0008201 heparin binding 39/5291 172/18639 0.226744186046512 0.798768641791898 0.962712203213789 1 GO:0047499 calcium-independent phospholipase A2 activity 5/5291 31/18639 0.161290322580645 0.568189439157181 0.963562998163449 1 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/5291 10/18639 0.1 0.352277452277452 0.964557846037832 1 GO:0008519 ammonium channel activity 1/5291 10/18639 0.1 0.352277452277452 0.964557846037832 1 GO:0015279 store-operated calcium channel activity 1/5291 10/18639 0.1 0.352277452277452 0.964557846037832 1 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/5291 10/18639 0.1 0.352277452277452 0.964557846037832 1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/5291 10/18639 0.1 0.352277452277452 0.964557846037832 1 GO:0031419 cobalamin binding 1/5291 10/18639 0.1 0.352277452277452 0.964557846037832 1 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/5291 10/18639 0.1 0.352277452277452 0.964557846037832 1 GO:0032052 bile acid binding 1/5291 10/18639 0.1 0.352277452277452 0.964557846037832 1 GO:0042166 acetylcholine binding 1/5291 10/18639 0.1 0.352277452277452 0.964557846037832 1 GO:0043121 neurotrophin binding 1/5291 10/18639 0.1 0.352277452277452 0.964557846037832 1 GO:0050308 sugar-phosphatase activity 1/5291 10/18639 0.1 0.352277452277452 0.964557846037832 1 GO:0051378 serotonin binding 1/5291 10/18639 0.1 0.352277452277452 0.964557846037832 1 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/5291 10/18639 0.1 0.352277452277452 0.964557846037832 1 GO:0097177 mitochondrial ribosome binding 1/5291 10/18639 0.1 0.352277452277452 0.964557846037832 1 GO:0140940 histone H2A methyltransferase activity 1/5291 10/18639 0.1 0.352277452277452 0.964557846037832 1 GO:1990259 histone H2AQ104 methyltransferase activity 1/5291 10/18639 0.1 0.352277452277452 0.964557846037832 1 GO:0052689 carboxylic ester hydrolase activity 19/5291 92/18639 0.206521739130435 0.727529521007782 0.964712694794429 1 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/5291 16/18639 0.125 0.440346815346815 0.964921757523318 1 GO:0015378 sodium:chloride symporter activity 2/5291 16/18639 0.125 0.440346815346815 0.964921757523318 1 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/5291 16/18639 0.125 0.440346815346815 0.964921757523318 1 GO:0008137 NADH dehydrogenase (ubiquinone) activity 7/5291 41/18639 0.170731707317073 0.601449308766382 0.968280554387072 1 GO:0017080 sodium channel regulator activity 7/5291 41/18639 0.170731707317073 0.601449308766382 0.968280554387072 1 GO:0140828 metal cation:monoatomic cation antiporter activity 7/5291 41/18639 0.170731707317073 0.601449308766382 0.968280554387072 1 GO:0019842 vitamin binding 33/5291 150/18639 0.22 0.775010395010395 0.96915381262431 1 GO:0016405 CoA-ligase activity 4/5291 27/18639 0.148148148148148 0.521892521892522 0.969812724674406 1 GO:0008970 phospholipase A1 activity 3/5291 22/18639 0.136363636363636 0.480378344014708 0.970368566579674 1 GO:0140784 metal ion sensor activity 3/5291 22/18639 0.136363636363636 0.480378344014708 0.970368566579674 1 GO:0015106 bicarbonate transmembrane transporter activity 5/5291 32/18639 0.15625 0.550433519183519 0.970602550419937 1 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 5/5291 32/18639 0.15625 0.550433519183519 0.970602550419937 1 GO:0047498 calcium-dependent phospholipase A2 activity 5/5291 32/18639 0.15625 0.550433519183519 0.970602550419937 1 GO:0008569 minus-end-directed microtubule motor activity 2/5291 17/18639 0.117647058823529 0.414444061502885 0.97353019388253 1 GO:0016018 cyclosporin A binding 2/5291 17/18639 0.117647058823529 0.414444061502885 0.97353019388253 1 GO:0030548 acetylcholine receptor regulator activity 2/5291 17/18639 0.117647058823529 0.414444061502885 0.97353019388253 1 GO:0045236 CXCR chemokine receptor binding 2/5291 17/18639 0.117647058823529 0.414444061502885 0.97353019388253 1 GO:0070492 oligosaccharide binding 2/5291 17/18639 0.117647058823529 0.414444061502885 0.97353019388253 1 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/5291 11/18639 0.0909090909090909 0.320252229343138 0.974624110282495 1 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/5291 11/18639 0.0909090909090909 0.320252229343138 0.974624110282495 1 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/5291 11/18639 0.0909090909090909 0.320252229343138 0.974624110282495 1 GO:0004523 RNA-DNA hybrid ribonuclease activity 1/5291 11/18639 0.0909090909090909 0.320252229343138 0.974624110282495 1 GO:0008046 axon guidance receptor activity 1/5291 11/18639 0.0909090909090909 0.320252229343138 0.974624110282495 1 GO:0008199 ferric iron binding 1/5291 11/18639 0.0909090909090909 0.320252229343138 0.974624110282495 1 GO:0008271 secondary active sulfate transmembrane transporter activity 1/5291 11/18639 0.0909090909090909 0.320252229343138 0.974624110282495 1 GO:0008503 benzodiazepine receptor activity 1/5291 11/18639 0.0909090909090909 0.320252229343138 0.974624110282495 1 GO:0016594 glycine binding 1/5291 11/18639 0.0909090909090909 0.320252229343138 0.974624110282495 1 GO:0019203 carbohydrate phosphatase activity 1/5291 11/18639 0.0909090909090909 0.320252229343138 0.974624110282495 1 GO:0047676 arachidonate-CoA ligase activity 1/5291 11/18639 0.0909090909090909 0.320252229343138 0.974624110282495 1 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/5291 11/18639 0.0909090909090909 0.320252229343138 0.974624110282495 1 GO:0050786 RAGE receptor binding 1/5291 11/18639 0.0909090909090909 0.320252229343138 0.974624110282495 1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/5291 11/18639 0.0909090909090909 0.320252229343138 0.974624110282495 1 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/5291 11/18639 0.0909090909090909 0.320252229343138 0.974624110282495 1 GO:0005253 monoatomic anion channel activity 21/5291 103/18639 0.203883495145631 0.718235582313252 0.975349990908464 1 GO:0004602 glutathione peroxidase activity 3/5291 23/18639 0.130434782608696 0.459492329057546 0.97701051336248 1 GO:0048029 monosaccharide binding 14/5291 74/18639 0.189189189189189 0.666470855660045 0.977484744100687 1 GO:0008194 UDP-glycosyltransferase activity 31/5291 145/18639 0.213793103448276 0.753144897972484 0.978114707563235 1 GO:0015373 monoatomic anion:sodium symporter activity 2/5291 18/18639 0.111111111111111 0.391419391419391 0.980078888952927 1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/5291 18/18639 0.111111111111111 0.391419391419391 0.980078888952927 1 GO:0099602 neurotransmitter receptor regulator activity 2/5291 18/18639 0.111111111111111 0.391419391419391 0.980078888952927 1 GO:0005506 iron ion binding 33/5291 154/18639 0.214285714285714 0.754880254880255 0.980246882081273 1 GO:0003785 actin monomer binding 4/5291 29/18639 0.137931034482759 0.485899934175796 0.981123195716092 1 GO:0004629 phospholipase C activity 4/5291 29/18639 0.137931034482759 0.485899934175796 0.981123195716092 1 GO:0051861 glycolipid binding 4/5291 29/18639 0.137931034482759 0.485899934175796 0.981123195716092 1 GO:0004126 cytidine deaminase activity 1/5291 12/18639 0.0833333333333333 0.293564543564544 0.981831745696674 1 GO:0008179 adenylate cyclase binding 1/5291 12/18639 0.0833333333333333 0.293564543564544 0.981831745696674 1 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/5291 12/18639 0.0833333333333333 0.293564543564544 0.981831745696674 1 GO:0008504 monoamine transmembrane transporter activity 1/5291 12/18639 0.0833333333333333 0.293564543564544 0.981831745696674 1 GO:0015132 prostaglandin transmembrane transporter activity 1/5291 12/18639 0.0833333333333333 0.293564543564544 0.981831745696674 1 GO:0070008 serine-type exopeptidase activity 1/5291 12/18639 0.0833333333333333 0.293564543564544 0.981831745696674 1 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/5291 12/18639 0.0833333333333333 0.293564543564544 0.981831745696674 1 GO:0140900 chloride:bicarbonate antiporter activity 1/5291 12/18639 0.0833333333333333 0.293564543564544 0.981831745696674 1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 3/5291 24/18639 0.125 0.440346815346815 0.98221865212327 1 GO:0042625 ATPase-coupled ion transmembrane transporter activity 3/5291 24/18639 0.125 0.440346815346815 0.98221865212327 1 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 3/5291 24/18639 0.125 0.440346815346815 0.98221865212327 1 GO:0046961 proton-transporting ATPase activity, rotational mechanism 3/5291 24/18639 0.125 0.440346815346815 0.98221865212327 1 GO:0005507 copper ion binding 11/5291 63/18639 0.174603174603175 0.615087615087615 0.984380220259612 1 GO:0004623 phospholipase A2 activity 5/5291 35/18639 0.142857142857143 0.503253503253503 0.98486112618773 1 GO:0005343 organic acid:sodium symporter activity 5/5291 35/18639 0.142857142857143 0.503253503253503 0.98486112618773 1 GO:0016229 steroid dehydrogenase activity 5/5291 35/18639 0.142857142857143 0.503253503253503 0.98486112618773 1 GO:0008301 DNA binding, bending 2/5291 19/18639 0.105263157894737 0.370818370818371 0.985043333423319 1 GO:0008574 plus-end-directed microtubule motor activity 2/5291 19/18639 0.105263157894737 0.370818370818371 0.985043333423319 1 GO:0015245 fatty acid transmembrane transporter activity 2/5291 19/18639 0.105263157894737 0.370818370818371 0.985043333423319 1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/5291 19/18639 0.105263157894737 0.370818370818371 0.985043333423319 1 GO:0022821 solute:potassium antiporter activity 2/5291 19/18639 0.105263157894737 0.370818370818371 0.985043333423319 1 GO:0042277 peptide binding 56/5291 249/18639 0.224899598393574 0.792270575403106 0.985727398507175 1 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 12/5291 68/18639 0.176470588235294 0.621666092254328 0.985727596373052 1 GO:0001848 complement binding 3/5291 25/18639 0.12 0.422732942732943 0.986286272972442 1 GO:0015296 monoatomic anion:monoatomic cation symporter activity 3/5291 25/18639 0.12 0.422732942732943 0.986286272972442 1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 3/5291 25/18639 0.12 0.422732942732943 0.986286272972442 1 GO:0004993 G protein-coupled serotonin receptor activity 1/5291 13/18639 0.0769230769230769 0.27098265559804 0.986992438965525 1 GO:0005542 folic acid binding 1/5291 13/18639 0.0769230769230769 0.27098265559804 0.986992438965525 1 GO:0089720 caspase binding 1/5291 13/18639 0.0769230769230769 0.27098265559804 0.986992438965525 1 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 5/5291 36/18639 0.138888888888889 0.489274239274239 0.987937954350743 1 GO:0042287 MHC protein binding 6/5291 41/18639 0.146341463414634 0.515527978942613 0.98799765239754 1 GO:0005310 dicarboxylic acid transmembrane transporter activity 4/5291 31/18639 0.129032258064516 0.454551551325745 0.988339239583672 1 GO:0005452 solute:inorganic anion antiporter activity 4/5291 31/18639 0.129032258064516 0.454551551325745 0.988339239583672 1 GO:0004180 carboxypeptidase activity 7/5291 46/18639 0.152173913043478 0.536074383900471 0.98834818111488 1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 7/5291 46/18639 0.152173913043478 0.536074383900471 0.98834818111488 1 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 7/5291 46/18639 0.152173913043478 0.536074383900471 0.98834818111488 1 GO:0001614 purinergic nucleotide receptor activity 2/5291 20/18639 0.1 0.352277452277452 0.988795091316448 1 GO:0005326 neurotransmitter transmembrane transporter activity 2/5291 20/18639 0.1 0.352277452277452 0.988795091316448 1 GO:0016502 nucleotide receptor activity 2/5291 20/18639 0.1 0.352277452277452 0.988795091316448 1 GO:0022829 wide pore channel activity 5/5291 37/18639 0.135135135135135 0.476050611185746 0.990415828119904 1 GO:0031404 chloride ion binding 1/5291 14/18639 0.0714285714285714 0.251626751626752 0.990687435499049 1 GO:0008395 steroid hydroxylase activity 3/5291 27/18639 0.111111111111111 0.391419391419391 0.991906411454453 1 GO:0023026 MHC class II protein complex binding 3/5291 27/18639 0.111111111111111 0.391419391419391 0.991906411454453 1 GO:0033218 amide binding 54/5291 247/18639 0.218623481781377 0.770161231699693 0.992102029622538 1 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 9/5291 58/18639 0.155172413793103 0.546637425947771 0.992897151478134 1 GO:0004467 long-chain fatty acid-CoA ligase activity 1/5291 15/18639 0.0666666666666667 0.234851634851635 0.993332953822514 1 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/5291 15/18639 0.0666666666666667 0.234851634851635 0.993332953822514 1 GO:0015116 sulfate transmembrane transporter activity 1/5291 15/18639 0.0666666666666667 0.234851634851635 0.993332953822514 1 GO:0140161 monocarboxylate:sodium symporter activity 1/5291 15/18639 0.0666666666666667 0.234851634851635 0.993332953822514 1 GO:0001664 G protein-coupled receptor binding 66/5291 297/18639 0.222222222222222 0.782838782838783 0.993646400268359 1 GO:0005243 gap junction channel activity 2/5291 22/18639 0.0909090909090909 0.320252229343138 0.99374786763006 1 GO:0015377 chloride:monoatomic cation symporter activity 2/5291 22/18639 0.0909090909090909 0.320252229343138 0.99374786763006 1 GO:0033038 bitter taste receptor activity 2/5291 22/18639 0.0909090909090909 0.320252229343138 0.99374786763006 1 GO:0033691 sialic acid binding 2/5291 22/18639 0.0909090909090909 0.320252229343138 0.99374786763006 1 GO:0015020 glucuronosyltransferase activity 4/5291 34/18639 0.117647058823529 0.414444061502885 0.994450580890563 1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 4/5291 34/18639 0.117647058823529 0.414444061502885 0.994450580890563 1 GO:0004896 cytokine receptor activity 17/5291 96/18639 0.177083333333333 0.623824655074655 0.994531910971213 1 GO:0005254 chloride channel activity 14/5291 83/18639 0.168674698795181 0.594202931552329 0.994945907072617 1 GO:0015385 sodium:proton antiporter activity 1/5291 16/18639 0.0625 0.220173407673408 0.995227033575793 1 GO:0022841 potassium ion leak channel activity 1/5291 16/18639 0.0625 0.220173407673408 0.995227033575793 1 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/5291 16/18639 0.0625 0.220173407673408 0.995227033575793 1 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/5291 16/18639 0.0625 0.220173407673408 0.995227033575793 1 GO:0015144 carbohydrate transmembrane transporter activity 5/5291 40/18639 0.125 0.440346815346815 0.995264719361727 1 GO:0004181 metallocarboxypeptidase activity 3/5291 29/18639 0.103448275862069 0.364424950631847 0.99526760336045 1 GO:0016917 GABA receptor activity 2/5291 23/18639 0.0869565217391304 0.306328219371698 0.995341901369829 1 GO:0015171 amino acid transmembrane transporter activity 18/5291 102/18639 0.176470588235294 0.621666092254328 0.995759794578113 1 GO:0005272 sodium channel activity 7/5291 51/18639 0.137254901960784 0.483518071753366 0.995993005166875 1 GO:0015293 symporter activity 28/5291 146/18639 0.191780821917808 0.675600593408813 0.996106816300405 1 GO:0020037 heme binding 27/5291 142/18639 0.190140845070423 0.669823324752902 0.996254068373153 1 GO:0008106 alcohol dehydrogenase (NADP+) activity 3/5291 30/18639 0.1 0.352277452277452 0.996392636488625 1 GO:0005200 structural constituent of cytoskeleton 20/5291 112/18639 0.178571428571429 0.629066879066879 0.996472736002078 1 GO:0015291 secondary active transmembrane transporter activity 62/5291 287/18639 0.21602787456446 0.76101749272481 0.996521561557086 1 GO:0019957 C-C chemokine binding 2/5291 24/18639 0.0833333333333333 0.293564543564544 0.996534924028607 1 GO:0009881 photoreceptor activity 1/5291 17/18639 0.0588235294117647 0.207222030751443 0.996583086056622 1 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/5291 17/18639 0.0588235294117647 0.207222030751443 0.996583086056622 1 GO:0036041 long-chain fatty acid binding 1/5291 17/18639 0.0588235294117647 0.207222030751443 0.996583086056622 1 GO:0004620 phospholipase activity 19/5291 109/18639 0.174311926605505 0.614061614061614 0.997203454736496 1 GO:0022853 active monoatomic ion transmembrane transporter activity 21/5291 118/18639 0.177966101694915 0.626934448968347 0.997257009015197 1 GO:0004175 endopeptidase activity 91/5291 405/18639 0.224691358024691 0.791536991536992 0.997304805981245 1 GO:0023023 MHC protein complex binding 4/5291 37/18639 0.108108108108108 0.380840488948597 0.997413143336047 1 GO:0005537 D-mannose binding 2/5291 25/18639 0.08 0.281821961821962 0.99742611107697 1 GO:0015645 fatty acid ligase activity 2/5291 25/18639 0.08 0.281821961821962 0.99742611107697 1 GO:0120515 fatty acid-CoA ligase activity 2/5291 25/18639 0.08 0.281821961821962 0.99742611107697 1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/5291 18/18639 0.0555555555555556 0.195709695709696 0.997553921180369 1 GO:0022851 GABA-gated chloride ion channel activity 1/5291 18/18639 0.0555555555555556 0.195709695709696 0.997553921180369 1 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 8/5291 59/18639 0.135593220338983 0.477664342071122 0.997905952884801 1 GO:0016651 oxidoreductase activity, acting on NAD(P)H 14/5291 88/18639 0.159090909090909 0.560441401350492 0.997942622853887 1 GO:0015294 solute:monoatomic cation symporter activity 20/5291 116/18639 0.172413793103448 0.607374917719745 0.998154759279862 1 GO:0004890 GABA-A receptor activity 1/5291 19/18639 0.0526315789473684 0.185409185409185 0.998248953833538 1 GO:0034987 immunoglobulin receptor binding 1/5291 19/18639 0.0526315789473684 0.185409185409185 0.998248953833538 1 GO:0099589 serotonin receptor activity 1/5291 19/18639 0.0526315789473684 0.185409185409185 0.998248953833538 1 GO:0008514 organic anion transmembrane transporter activity 56/5291 269/18639 0.20817843866171 0.733365699908451 0.998260367735589 1 GO:0046906 tetrapyrrole binding 28/5291 152/18639 0.184210526315789 0.648932148932149 0.998360578104953 1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3/5291 33/18639 0.0909090909090909 0.320252229343138 0.99841987440187 1 GO:0048306 calcium-dependent protein binding 12/5291 80/18639 0.15 0.528416178416178 0.998435019066219 1 GO:0015252 proton channel activity 2/5291 27/18639 0.0740740740740741 0.260946260946261 0.998585396880598 1 GO:0042605 peptide antigen binding 5/5291 45/18639 0.111111111111111 0.391419391419391 0.998601157972111 1 GO:0004867 serine-type endopeptidase inhibitor activity 15/5291 95/18639 0.157894736842105 0.556227556227556 0.998661699508229 1 GO:0015464 acetylcholine receptor activity 1/5291 20/18639 0.05 0.176138726138726 0.998746525544964 1 GO:0030627 pre-mRNA 5'-splice site binding 1/5291 20/18639 0.05 0.176138726138726 0.998746525544964 1 GO:0022804 active transmembrane transporter activity 102/5291 457/18639 0.223194748358862 0.78626477313567 0.998775246650383 1 GO:0008527 taste receptor activity 2/5291 28/18639 0.0714285714285714 0.251626751626752 0.998953166734755 1 GO:0004601 peroxidase activity 7/5291 57/18639 0.12280701754386 0.432621432621433 0.998963593882625 1 GO:0015125 bile acid transmembrane transporter activity 1/5291 21/18639 0.0476190476190476 0.167751167751168 0.999102727990938 1 GO:0005504 fatty acid binding 5/5291 47/18639 0.106382978723404 0.374763247103673 0.999152540947885 1 GO:0099095 ligand-gated monoatomic anion channel activity 5/5291 47/18639 0.106382978723404 0.374763247103673 0.999152540947885 1 GO:0005539 glycosaminoglycan binding 48/5291 242/18639 0.198347107438017 0.698732136748666 0.999164641644629 1 GO:0016298 lipase activity 22/5291 130/18639 0.169230769230769 0.596161842315688 0.999195628841456 1 GO:0033293 monocarboxylic acid binding 11/5291 79/18639 0.139240506329114 0.490512908234427 0.999281473971217 1 GO:0004033 aldo-keto reductase (NADPH) activity 3/5291 36/18639 0.0833333333333333 0.293564543564544 0.999317899686027 1 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/5291 36/18639 0.0833333333333333 0.293564543564544 0.999317899686027 1 GO:0008509 monoatomic anion transmembrane transporter activity 26/5291 149/18639 0.174496644295302 0.614712332833138 0.999325855435626 1 GO:0038187 pattern recognition receptor activity 5/5291 48/18639 0.104166666666667 0.366955679455679 0.999342072843547 1 GO:0030280 structural constituent of skin epidermis 3/5291 37/18639 0.0810810810810811 0.285630366711448 0.99948596642279 1 GO:0016209 antioxidant activity 12/5291 86/18639 0.13953488372093 0.491549933410398 0.99953036890035 1 GO:0016493 C-C chemokine receptor activity 1/5291 23/18639 0.0434782608695652 0.153164109685849 0.999540258612894 1 GO:0061134 peptidase regulator activity 43/5291 226/18639 0.190265486725664 0.670262409200462 0.999574373233136 1 GO:0170055 lipid transmembrane transporter activity 6/5291 56/18639 0.107142857142857 0.377440127440127 0.999638560730439 1 GO:0004806 triacylglycerol lipase activity 1/5291 24/18639 0.0416666666666667 0.146782271782272 0.99967092533395 1 GO:0043177 organic acid binding 34/5291 189/18639 0.17989417989418 0.633726633726634 0.999674505414134 1 GO:0099094 ligand-gated monoatomic cation channel activity 22/5291 136/18639 0.161764705882353 0.569860584566467 0.999711104949461 1 GO:0015370 solute:sodium symporter activity 10/5291 79/18639 0.126582278481013 0.445920825667661 0.99975572602988 1 GO:0015271 outward rectifier potassium channel activity 1/5291 25/18639 0.04 0.140910980910981 0.999764459261324 1 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 5/5291 52/18639 0.0961538461538462 0.33872831949755 0.999764704796844 1 GO:0031406 carboxylic acid binding 33/5291 187/18639 0.176470588235294 0.621666092254328 0.999774097272368 1 GO:0003730 mRNA 3'-UTR binding 50/5291 262/18639 0.190839694656489 0.672285214269947 0.999815874643018 1 GO:0022832 voltage-gated channel activity 30/5291 175/18639 0.171428571428571 0.603904203904204 0.999816978310022 1 GO:0008028 monocarboxylic acid transmembrane transporter activity 8/5291 70/18639 0.114285714285714 0.402602802602803 0.999827266630669 1 GO:0001637 G protein-coupled chemoattractant receptor activity 1/5291 26/18639 0.0384615384615385 0.13549132779902 0.999831411343001 1 GO:0004950 chemokine receptor activity 1/5291 26/18639 0.0384615384615385 0.13549132779902 0.999831411343001 1 GO:0019825 oxygen binding 2/5291 34/18639 0.0588235294117647 0.207222030751443 0.999831624309048 1 GO:0001530 lipopolysaccharide binding 3/5291 41/18639 0.0731707317073171 0.257763989471307 0.99983627111606 1 GO:0008227 G protein-coupled amine receptor activity 3/5291 41/18639 0.0731707317073171 0.257763989471307 0.99983627111606 1 GO:0005244 voltage-gated monoatomic ion channel activity 29/5291 173/18639 0.167630057803468 0.590522896881278 0.999878163438287 1 GO:0004364 glutathione transferase activity 1/5291 27/18639 0.037037037037037 0.13047313047313 0.99987933497617 1 GO:0015103 inorganic anion transmembrane transporter activity 27/5291 165/18639 0.163636363636364 0.576454012817649 0.999898492272928 1 GO:0004497 monooxygenase activity 14/5291 106/18639 0.132075471698113 0.465272106781541 0.999941572493392 1 GO:0015108 chloride transmembrane transporter activity 17/5291 121/18639 0.140495867768595 0.494935263530305 0.99994297524771 1 GO:0004866 endopeptidase inhibitor activity 25/5291 161/18639 0.15527950310559 0.54701467744946 0.999959425168102 1 GO:0022843 voltage-gated monoatomic cation channel activity 21/5291 143/18639 0.146853146853147 0.517330524323531 0.999965831975936 1 GO:0005184 neuropeptide hormone activity 1/5291 31/18639 0.032258064516129 0.113637887831436 0.999968340728036 1 GO:0071855 neuropeptide receptor binding 2/5291 40/18639 0.05 0.176138726138726 0.999973669085671 1 GO:0160041 neuropeptide activity 1/5291 32/18639 0.03125 0.110086703836704 0.999977342727604 1 GO:0030414 peptidase inhibitor activity 26/5291 169/18639 0.153846153846154 0.54196531119608 0.999977680238381 1 GO:0046943 carboxylic acid transmembrane transporter activity 30/5291 188/18639 0.159574468085106 0.562144870655509 0.999979176456311 1 GO:0061135 endopeptidase regulator activity 29/5291 184/18639 0.157608695652174 0.555219897611202 0.999981336409284 1 GO:0005342 organic acid transmembrane transporter activity 30/5291 189/18639 0.158730158730159 0.559170559170559 0.999982499245102 1 GO:0042923 neuropeptide binding 1/5291 33/18639 0.0303030303030303 0.106750743114379 0.99998378544423 1 GO:0015078 proton transmembrane transporter activity 29/5291 185/18639 0.156756756756757 0.552218708975466 0.999984352242502 1 GO:0048020 CCR chemokine receptor binding 3/5291 50/18639 0.06 0.211366471366471 0.999988244176613 1 GO:0005249 voltage-gated potassium channel activity 11/5291 98/18639 0.112244897959184 0.395413466842038 0.999989118993107 1 GO:0003735 structural constituent of ribosome 26/5291 175/18639 0.148571428571429 0.523383643383643 0.999992582667588 1 GO:0008009 chemokine activity 2/5291 45/18639 0.0444444444444444 0.156567756567757 0.999994480093237 1 GO:0001653 peptide receptor activity 16/5291 128/18639 0.125 0.440346815346815 0.999995282557499 1 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 6/5291 73/18639 0.0821917808219178 0.28954311146092 0.999995520289658 1 GO:0008188 neuropeptide receptor activity 2/5291 48/18639 0.0416666666666667 0.146782271782272 0.999997850600472 1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 3/5291 56/18639 0.0535714285714286 0.188720063720064 0.999998040140749 1 GO:0015081 sodium ion transmembrane transporter activity 22/5291 164/18639 0.134146341463415 0.472567314030729 0.999998567865073 1 GO:0005267 potassium channel activity 14/5291 124/18639 0.112903225806452 0.397732607410027 0.99999888223016 1 GO:0042379 chemokine receptor binding 5/5291 72/18639 0.0694444444444444 0.24463711963712 0.999998965805742 1 GO:0046873 metal ion transmembrane transporter activity 85/5291 450/18639 0.188888888888889 0.665412965412965 0.999999015059426 1 GO:0015276 ligand-gated monoatomic ion channel activity 26/5291 186/18639 0.139784946236559 0.492430847269557 0.999999093661456 1 GO:0005125 cytokine activity 36/5291 234/18639 0.153846153846154 0.54196531119608 0.999999139307232 1 GO:0022834 ligand-gated channel activity 26/5291 188/18639 0.138297872340426 0.487192221234774 0.999999388142887 1 GO:0008528 G protein-coupled peptide receptor activity 13/5291 122/18639 0.10655737704918 0.375377613082531 0.999999494647961 1 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/5291 53/18639 0.0377358490566038 0.132934887651869 0.99999955729402 1 GO:0022824 transmitter-gated monoatomic ion channel activity 3/5291 63/18639 0.0476190476190476 0.167751167751168 0.999999764215748 1 GO:0022835 transmitter-gated channel activity 3/5291 63/18639 0.0476190476190476 0.167751167751168 0.999999764215748 1 GO:0140375 immune receptor activity 18/5291 156/18639 0.115384615384615 0.40647398339706 0.999999900688638 1 GO:0030246 carbohydrate binding 43/5291 280/18639 0.153571428571429 0.540997515997516 0.999999918674915 1 GO:0015079 potassium ion transmembrane transporter activity 18/5291 160/18639 0.1125 0.396312133812134 0.999999959679677 1 GO:0098960 postsynaptic neurotransmitter receptor activity 3/5291 69/18639 0.0434782608695652 0.153164109685849 0.999999962351848 1 GO:0005261 monoatomic cation channel activity 55/5291 341/18639 0.161290322580645 0.568189439157181 0.999999968829273 1 GO:0005179 hormone activity 12/5291 132/18639 0.0909090909090909 0.320252229343138 0.99999998888354 1 GO:0030594 neurotransmitter receptor activity 6/5291 97/18639 0.0618556701030928 0.217903578728321 0.999999994160628 1 GO:0004252 serine-type endopeptidase activity 19/5291 176/18639 0.107954545454545 0.380299522344977 0.99999999645075 1 GO:0022836 gated channel activity 46/5291 318/18639 0.144654088050314 0.50958373599883 0.999999998948634 1 GO:0005216 monoatomic ion channel activity 74/5291 448/18639 0.165178571428571 0.581886863136863 0.999999998981667 1 GO:0008236 serine-type peptidase activity 21/5291 194/18639 0.108247422680412 0.381331262774562 0.999999999318532 1 GO:0017171 serine hydrolase activity 21/5291 198/18639 0.106060606060606 0.373627600900328 0.999999999729896 1 GO:0005549 odorant binding 2/5291 111/18639 0.018018018018018 0.0634734148247662 0.999999999999997 1 GO:0003823 antigen binding 8/5291 174/18639 0.0459770114942529 0.161966644725265 1 1 GO:0004984 olfactory receptor activity 7/5291 419/18639 0.0167064439140811 0.0588530349866865 1 1 GO:0030371 translation repressor activity 11/5291 329/18639 0.033434650455927 0.117782734804011 1 1 GO:0045182 translation regulator activity 18/5291 356/18639 0.050561797752809 0.178117812949274 1 1