category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	10/104	142/9376	6.34886240520043	HSP90AB1/HSP90AA1/FOS/DUSP1/JUN/CTNNB1/GSTT2B/ACTB/CAV1/PDGFA	6.80183761723704
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	10/104	174/9376	5.18125552608311	HSPA1B/DNAJB1/DNAJA1/HSP90AB1/HSP90AA1/HSPH1/DDIT3/HSPA8/HERPUD1/HSPA5	5.89597746771538
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	11/104	238/9376	4.16677440206852	FOS/OAS1/RPL36A/JUN/RPL17/OAS3/RPS17/ISG15/RPS10/EIF2AK2/OAS2	5.24077631627199
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	7/104	94/9376	6.71358428805237	HSP90AB1/HSP90AA1/FOS/FOSB/JUN/JUND/USP25	5.89613447019653
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	11/104	248/9376	3.99875930521092	HSP90AB1/HSP90AA1/FOS/RHOB/JUN/CTNNB1/ACTB/DCTN4/DYNLL1/AHNAK/CYTH3	5.06868415283883
Human Diseases	Infectious disease: viral	hsa05162	Measles	8/104	136/9376	5.30316742081448	HSPA1B/FOS/OAS1/JUN/HSPA8/OAS3/EIF2AK2/OAS2	5.35349385119726
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	8/104	156/9376	4.6232741617357	IFIT1/OAS1/CTNNB1/OAS3/YWHAZ/YWHAG/EIF2AK2/OAS2	4.83296479941077
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	8/104	157/9376	4.59382655561	CTNNB1/PPP1CB/ACTB/YWHAZ/YWHAG/PARD6B/SERPINE1/YAP1	4.80928626533544
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	9/104	204/9376	3.97737556561086	CTNNB1/PPP1CB/MDM2/ACTB/CAV1/EZR/DDX5/PDCD4/EIF4B	4.55336302911562
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	11/104	300/9376	3.30564102564103	HSPA1B/FOS/DUSP1/JUN/DUSP5/DDIT3/HSPA8/JUND/DUSP6/PDGFA/EPHA2	4.29853701988081
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	9/104	216/9376	3.75641025641026	HSPA1B/HSP90AB1/HSP90AA1/FOS/JUN/HSPD1/DDIT3/HSPA8/HSPA5	4.34048832440292
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	7/104	139/9376	4.54012174875484	HSPA1B/HSP90AB1/HSP90AA1/KRT19/FOS/JUN/HSPA8	4.45323611887039
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	5/104	78/9376	5.77909270216963	HSPD1/DIS3L/TOB2/TOB1/PATL1	4.48862766243289
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	9/104	250/9376	3.24553846153846	HSPA1B/HSPA8/MDM2/TFRC/CAV1/PARD6B/IST1/CYTH3/CLTC	3.81123621480964
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	8/104	203/9376	3.55286093217128	JUN/CTNNB1/PPP1CB/ACTB/LAMC2/CAV1/ACTN4/PDGFA	3.89435085256359
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	8/104	205/9376	3.51819887429644	OAS1/JUN/MDM2/OAS3/ISG15/EIF2AK2/SKP2/OAS2	3.86077245112667
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	8/104	205/9376	3.51819887429644	GTF2H2/JUN/MDM2/YWHAZ/YWHAG/ACTN4/EIF2AK2/SKP2	3.86077245112667
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	5/104	82/9376	5.49718574108818	HSPA1B/HSP90AB1/HSP90AA1/HSPA8/HSPA5	4.33173632966653
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	5/104	106/9376	4.25253991291727	HSP90AB1/HSP90AA1/CTNNB1/MDM2/PDGFA	3.56657447039451
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	4/104	69/9376	5.2263099219621	FOS/FOSB/JUN/PPP1CB	3.73161324734846
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	5/104	109/9376	4.13549752999294	HSP90AB1/HSP90AA1/FOS/JUN/GATA3	3.48711063852257
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	5/104	115/9376	3.91973244147157	FOS/EGR1/GATA3/JUND/GCM1	3.33640397412281
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	4/104	78/9376	4.6232741617357	CTNNB1/ACTB/CAV1/CLTC	3.40305778616971
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	6/104	173/9376	3.12672298799466	DNAJB1/OAS1/ACTB/OAS3/EIF2AK2/OAS2	2.99009414350993
NA	NA	hsa04519	Cadherin signaling	10/104	404/9376	2.23153084539223	KRT19/DSP/CTNNB1/PPP1CB/ACTB/YWHAZ/YWHAG/KRT8/ACTN4/YAP1	2.67982812208309
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	6/104	187/9376	2.89263677498972	HSP90AB1/HSP90AA1/OAS1/JUN/OAS3/OAS2	2.76865950262895
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	9/104	362/9376	2.24139396515087	HSP90AB1/HSP90AA1/MDM2/LAMC2/YWHAZ/YWHAG/PDGFA/EIF4B/EPHA2	2.55106036061002
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	5/104	142/9376	3.17443120260022	FOS/FOSB/JUN/JUND/JUNB	2.76509785250045
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	7/104	253/9376	2.49437519002736	UBE2V1/JUN/MDM2/ACTB/FOXO4/ACTN4/CYTH3	2.55191772377674
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	3/104	56/9376	4.82967032967033	HSPA1B/HSPD1/HSPA8	3.04412893954596
NA	NA	hsa04518	Integrin signaling	5/104	154/9376	2.92707292707293	CTNNB1/ACTB/LAMC2/ACTN4/PDGFA	2.55365102813042
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	5/104	158/9376	2.85296981499513	MDM2/YWHAZ/YWHAG/SKP2/SFN	2.48767781203511
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	7/104	275/9376	2.29482517482517	HSPA1B/EGR1/PSMA6/DDIT3/HSPA8/CAV1/HSPA5	2.3080675798805
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	6/104	217/9376	2.49273307337823	HSP90AB1/HSP90AA1/FOS/KLF4/JUN/GSTT2B	2.35615354533362
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	4/104	110/9376	3.27832167832168	ALDOA/TFRC/LDHA/SERPINE1	2.54554532032226
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	4/104	112/9376	3.21978021978022	HSPA1B/HSPA8/LAMC2/IL10RB	2.50285281955755
Genetic Information Processing	Translation	hsa03010	Ribosome	6/104	222/9376	2.43659043659044	RPL36A/RPL17/RPS17/MRPL30/RPS10/MRPS17	2.29413832724161
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	4/104	116/9376	3.10875331564987	CTNNB1/ACTB/EZR/ACTN4	2.42027589875351
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	5/104	170/9376	2.65158371040724	JUN/ACTB/EZR/PARD6B/ACTN4	2.30146917531086
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	3/104	70/9376	3.86373626373626	EIF4G2/ACTB/CAV1	2.54692473593546
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	5/104	180/9376	2.5042735042735	OAS1/PPP1CB/OAS3/EIF2AK2/OAS2	2.15813781080192
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	3/104	75/9376	3.60615384615385	MDM2/SERPINE1/SFN	2.39983539947399
Metabolism	Global and overview maps	hsa01250	Biosynthesis of nucleotide sugars	2/104	37/9376	4.87318087318087	UGP2/GFPT1	2.49996569490818
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	2/104	37/9376	4.87318087318087	CTNNB1/TPM3	2.49996569490818
Cellular Processes	Cell motility	hsa04814	Motor proteins	5/104	194/9376	2.32355273592387	TPM4/ACTB/DCTN4/DYNLL1/TPM3	1.97282729165984
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	4/104	137/9376	2.63222908478383	FOS/JUN/DDIT3/ACTB	2.03818925956147
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	2/104	38/9376	4.74493927125506	UGP2/GFPT1	2.44976959055419
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	5/104	196/9376	2.29984301412873	FOS/JUN/CTNNB1/ZFP36/EIF2AK2	1.94766022807518
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	3/104	86/9376	3.14490161001789	DSP/CTNNB1/ACTB	2.11623718002958
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	5/104	200/9376	2.25384615384615	FOS/JUN/ACTB/EZR/CYTH3	1.89822698877391
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	3/104	87/9376	3.10875331564987	FOS/JUN/CTNNB1	2.09274599607505
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	5/104	201/9376	2.24263298890165	DDIT3/MDM2/DUSP6/DDX5/PDGFA	1.88605115357654
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	4/104	144/9376	2.5042735042735	KLF4/CTNNB1/ID4/ID3	1.92652988612375
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	3/104	93/9376	2.90818858560794	CTNNB1/ACTB/ACTN4	1.95854786200059
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	3/104	93/9376	2.90818858560794	FOS/JUN/GATA3	1.95854786200059
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	3/104	93/9376	2.90818858560794	LAMC2/SKP2/CKS2	1.95854786200059
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	2/104	44/9376	4.0979020979021	DCTN4/DYNLL1	2.18133445022332
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	5/104	212/9376	2.12626995645864	CTNNB1/ACTB/PARD6B/PDGFA/EPHA2	1.75664290494881
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	4/104	154/9376	2.34165834165834	FOS/JUN/PPP1CB/ACTB	1.7778918251836
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	4/104	157/9376	2.296913277805	ZFP36L1/PPP1CB/MDM2/SERPINE1	1.7355392971156
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	3/104	99/9376	2.73193473193473	FOS/JUN/MDM2	1.83468257796978
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	3/104	99/9376	2.73193473193473	FOS/JUN/PDGFA	1.83468257796978
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	3/104	99/9376	2.73193473193473	TPM4/ACTB/TPM3	1.83468257796978
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	3/104	101/9376	2.67783701447068	EGR1/JUN/SERPINE1	1.79543255327083
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	2/104	49/9376	3.67974882260597	FOSB/JUN	1.99175876395036
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/104	103/9376	2.62584017923824	FOS/JUN/SERPINE1	1.75712205869555
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	3/104	103/9376	2.62584017923824	SERPINB9/LAMC2/ACTN4	1.75712205869555
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	3/104	105/9376	2.57582417582418	TPM4/ACTB/TPM3	1.71970801106247
NA	NA	hsa04517	IgSF CAM signaling	6/104	299/9376	1.80910728067919	CTNNB1/ACTB/EZR/PARD6B/DYNLL1/ACTN4	1.50586532115457
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	5/104	232/9376	1.94297082228117	PPP1CB/ACTB/EZR/ACTN4/PDGFA	1.5402447423021
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	3/104	110/9376	2.45874125874126	TFRC/ID4/ID3	1.62983656789203
Genetic Information Processing	Transcription	hsa03040	Spliceosome	5/104	243/9376	1.85501741057297	HSPA1B/HSPA8/DDX5/THOC3/HNRNPU	1.43016769094988
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	3/104	119/9376	2.27278603749192	FOS/JUN/JUNB	1.47982155057178
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	2/104	62/9376	2.90818858560794	HSPA1B/HSPA8	1.59648417496032
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	3/104	122/9376	2.21689785624212	CTNNB1/MDM2/ACTB	1.43279774771629
Metabolism	Amino acid metabolism	hsa00360	Phenylalanine metabolism	1/104	16/9376	5.63461538461539	AOC2	1.96494935956126
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	6/104	333/9376	1.62439362439362	CTNNB1/MDM2/ISG15/LAMC2/PARD6B/EIF2AK2	1.22868316452109
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	2/104	66/9376	2.73193473193473	JUN/GATA3	1.49535478661241
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	2/104	67/9376	2.69115958668197	ALDOA/LDHA	1.47124864002894
NA	NA	hsa03273	Virion - Lassa virus and SFTS virus	1/104	17/9376	5.30316742081448	TFRC	1.88067424303339
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	3/104	133/9376	2.03354540196645	MDM2/FOXO4/SKP2	1.27134816215609
Human Diseases	Cancer: specific types	hsa05218	Melanoma	2/104	73/9376	2.46996838777661	MDM2/PDGFA	1.3352835880726
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	3/104	138/9376	1.95986622073579	PPP1CB/YWHAZ/YWHAG	1.20303113998575
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	3/104	138/9376	1.95986622073579	FOS/JUN/ACTB	1.20303113998575
Metabolism	Glycan biosynthesis and metabolism	hsa00541	Biosynthesis of various nucleotide sugars	1/104	20/9376	4.50769230769231	UGP2	1.66305640035941
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	2/104	75/9376	2.40410256410256	GSTT2B/MDM2	1.2929455576072
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	2/104	76/9376	2.37246963562753	ACTB/EZR	1.27228282106163
Human Diseases	Cancer: specific types	hsa05214	Glioma	2/104	76/9376	2.37246963562753	MDM2/PDGFA	1.27228282106163
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	3/104	142/9376	1.90465872156013	MDM2/SKP2/UBE2O	1.15040194660582
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	2/104	78/9376	2.31163708086785	FOS/JUN	1.23191803364336
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	2/104	78/9376	2.31163708086785	FOS/JUN	1.23191803364336
NA	NA	hsa04382	Cornified envelope formation	4/104	217/9376	1.66182204891882	KRT19/DSP/LAMC2/KRT8	1.04463041299878
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	3/104	148/9376	1.82744282744283	FOS/JUN/CTNNB1	1.07455996714761
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	4/104	224/9376	1.60989010989011	FOS/EGR1/JUN/ZFP36	0.978437728264485
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	3/104	154/9376	1.75624375624376	TPM4/PPP1CB/TPM3	1.00213262223677
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	2/104	87/9376	2.07250221043325	TPM4/TPM3	1.0643609615258
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	3/104	157/9376	1.72268495835375	FOS/JUN/DDIT3	0.967102555060638
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	4/104	233/9376	1.54770551337075	DSP/TPM4/ACTB/TPM3	0.896594993941875
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	2/104	90/9376	2.0034188034188	FOS/JUN	1.01298904009329
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	2/104	91/9376	1.98140321217244	FOS/JUN	0.996306155654632
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	3/104	163/9376	1.65927324209533	FOS/JUN/YWHAZ	0.899237298834666
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/104	93/9376	1.93879239040529	EGR1/JUN	0.9635681939188
Environmental Information Processing	Signal transduction	hsa04392	Hippo signaling pathway - multiple species	1/104	29/9376	3.10875331564987	YAP1	1.20449292239768
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/104	95/9376	1.89797570850202	FOS/JUN	0.931632437239891
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	3/104	168/9376	1.60989010989011	HSP90AB1/HSP90AA1/EIF2AK2	0.84477134254404
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	5/104	323/9376	1.39557037389855	MDM2/SPRY2/EZR/PDGFA/PDCD4	0.766203894603346
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	3/104	170/9376	1.59095022624434	CTNNB1/GSTT2B/ACTB	0.823484587111228
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/104	31/9376	2.90818858560794	ALDOA	1.12701081618563
Metabolism	Metabolism of other amino acids	hsa00410	beta-Alanine metabolism	1/104	31/9376	2.90818858560794	AOC2	1.12701081618563
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	1/104	31/9376	2.90818858560794	HSPA5	1.12701081618563
Metabolism	Carbohydrate metabolism	hsa00052	Galactose metabolism	1/104	32/9376	2.81730769230769	UGP2	1.09056771190663
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/104	32/9376	2.81730769230769	LDHA	1.09056771190663
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	1/104	33/9376	2.73193473193473	STX6	1.05550650327267
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/104	34/9376	2.65158371040724	BHLHE40	1.02172898574054
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	1/104	35/9376	2.57582417582418	ALDOA	0.989146666021325
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	2/104	105/9376	1.71721611721612	JUN/MDM2	0.78270299527204
Metabolism	Carbohydrate metabolism	hsa00040	Pentose and glucuronate interconversions	1/104	36/9376	2.5042735042735	UGP2	0.95767955216617
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/104	36/9376	2.5042735042735	UGP2	0.95767955216617
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	2/104	108/9376	1.66951566951567	IPO7/THOC3	0.741131389191366
Metabolism	Amino acid metabolism	hsa00250	Alanine, aspartate and glutamate metabolism	1/104	37/9376	2.43659043659044	GFPT1	0.927255123554242
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/104	37/9376	2.43659043659044	AOC2	0.927255123554242
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	2/104	109/9376	1.65419901199718	FOS/JUN	0.727560558611394
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	2/104	109/9376	1.65419901199718	PPP1CB/GFPT1	0.727560558611394
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	2/104	110/9376	1.63916083916084	HSP90AB1/HSP90AA1	0.714127815461799
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/104	38/9376	2.37246963562753	SFN	0.897807449943643
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	4/104	268/9376	1.34557979334099	DUSP1/PSMA6/DDIT3/HSPA5	0.607882754892213
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	1/104	41/9376	2.19887429643527	AOC2	0.814749331351731
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/104	41/9376	2.19887429643527	MDM2	0.814749331351731
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	2/104	117/9376	1.54109138724523	ACTB/MORF4L2	0.623730679636263
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/104	42/9376	2.14652014652015	TFRC	0.788656766465308
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	5/104	368/9376	1.22491638795987	PSMA6/DDIT3/ACTB/DCTN4/HSPA5	0.466172249733259
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	1/104	44/9376	2.04895104895105	GTF2H2	0.738600829646722
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/104	44/9376	2.04895104895105	HSPD1	0.738600829646722
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	2/104	122/9376	1.47793190416141	FOS/JUN	0.562725747548678
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/104	122/9376	1.47793190416141	FOS/JUNB	0.562725747548678
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	1/104	46/9376	1.95986622073579	PSMA6	0.691137406148605
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	1/104	47/9376	1.91816693944354	LDHA	0.668295643146605
Organismal Systems	Immune system	hsa04611	Platelet activation	2/104	126/9376	1.43101343101343	PPP1CB/ACTB	0.515846877682206
NA	NA	hsa03272	Virion - Hepatitis viruses	1/104	48/9376	1.87820512820513	IST1	0.646008028161351
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/104	130/9376	1.38698224852071	FOS/JUN	0.470545226130397
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	3/104	214/9376	1.26383896477354	FOS/JUN/APOBEC3B	0.413491202226647
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/104	51/9376	1.76772247360483	ACTB	0.582211149598672
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	2/104	133/9376	1.3556969346443	FOS/PPP1CB	0.43753728020481
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	4/104	308/9376	1.17082917082917	PSMA6/TGM2/DCTN4/CLTC	0.322847354335924
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/104	53/9376	1.70101596516691	CLTC	0.542005380617517
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/104	54/9376	1.66951566951567	LDHA	0.522538955455978
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	3/104	226/9376	1.19673247106875	FOS/JUN/PPP1CB	0.317055517908922
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	2/104	140/9376	1.28791208791209	EGR1/SERPINE1	0.363494254857536
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	3/104	227/9376	1.191460521857	CTNNB1/MDM2/IL10RB	0.309258004666943
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	3/104	227/9376	1.191460521857	FOS/JUN/GSTT2B	0.309258004666943
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/104	56/9376	1.60989010989011	EVC2	0.484789544174464
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/104	59/9376	1.52803129074316	GSTT2B	0.430886823627403
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/104	59/9376	1.52803129074316	CTNNB1	0.430886823627403
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	3/104	238/9376	1.13639301874596	FOXO4/PDGFA/EPHA2	0.22572031082535
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	2/104	149/9376	1.21011874032008	PDGFA/CYTH3	0.273806187902565
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/104	63/9376	1.43101343101343	GTF2H2	0.363522982833709
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/104	63/9376	1.43101343101343	CTNNB1	0.363522982833709
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	2/104	155/9376	1.16327543424318	ACTB/TFRC	0.217076735541158
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	2/104	158/9376	1.14118792599805	SKP2/EIF4B	0.189549807012659
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/104	67/9376	1.34557979334099	PPP1CB	0.300642118566674
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/104	68/9376	1.32579185520362	DUSP6	0.285549949807947
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/104	70/9376	1.28791208791209	GSTT2B	0.256060737074095
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/104	70/9376	1.28791208791209	JUN	0.256060737074095
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/104	71/9376	1.26977248104009	FOS	0.241648569222516
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/104	71/9376	1.26977248104009	JUN	0.241648569222516
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/104	71/9376	1.26977248104009	LDHA	0.241648569222516
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/104	72/9376	1.25213675213675	ISG15	0.227448537137993
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/104	73/9376	1.2349841938883	GSTT2B	0.213453935584365
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/104	73/9376	1.2349841938883	APOBEC3B	0.213453935584365
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/104	168/9376	1.07326007326007	IL10RB/PDGFA	0.101474035140425
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/104	75/9376	1.20205128205128	ALDOA	0.186055715740408
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/104	75/9376	1.20205128205128	HSPA5	0.186055715740408
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/104	76/9376	1.18623481781377	PLIN2	0.172640146810722
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/104	77/9376	1.17082917082917	MDM2	0.159406074846791
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/104	79/9376	1.14118792599805	GSTT2B	0.133461279818734
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/104	79/9376	1.14118792599805	CLTC	0.133461279818734
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	2/104	178/9376	1.01296456352636	JUN/CTNNB1	0.0184942530239063
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/104	80/9376	1.12692307692308	PDGFA	0.120740542888842
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/104	181/9376	0.996175095622609	HSPD1/IL10RB	-0.00550300109568755
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/104	82/9376	1.09943714821764	GSTT2B	0.0957789009062687
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/104	83/9376	1.08619091751622	EPOP	0.0835291722810465
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	2/104	184/9376	0.979933110367893	PARD6B/EPHA2	-0.029113844770314
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/104	86/9376	1.04830053667263	JUN	0.0476550490915752
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	5/104	480/9376	0.939102564102564	PSMA6/DDIT3/CTNNB1/DCTN4/HSPA5	-0.145056713933539
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	1/104	88/9376	1.02447552447552	SERPINE1	0.0244302457665082
Human Diseases	Substance dependence	hsa05034	Alcoholism	2/104	191/9376	0.944019331453886	FOSB/PPP1CB	-0.0827810213428759
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	4/104	388/9376	0.929421094369548	PSMA6/DDIT3/CTNNB1/EIF2AK2	-0.150374725429597
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/104	89/9376	1.01296456352636	LAMC2	0.0130145985702607
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/104	89/9376	1.01296456352636	PDGFA	0.0130145985702607
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/104	97/9376	0.929421094369548	FOS	-0.0739989906913193
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	2/104	205/9376	0.879549718574109	PPP1CB/GFPT1	-0.184668150322107
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/104	99/9376	0.910644910644911	PPP1CB	-0.0946561222371131
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/104	99/9376	0.910644910644911	KRT19	-0.0946561222371131
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/104	100/9376	0.901538461538462	IL10RB	-0.104833924413247
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	1/104	100/9376	0.901538461538462	TFRC	-0.104833924413247
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/104	101/9376	0.892612338156893	CTNNB1	-0.114914203364134
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/104	103/9376	0.875280059746079	PPP1CB	-0.134790713735488
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/104	105/9376	0.858608058608059	JUN	-0.15430202051839
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/104	107/9376	0.842559309849029	LDHA	-0.173463469649638
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/104	115/9376	0.783946488294314	FOS	-0.24688625054792
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/104	115/9376	0.783946488294314	DUSP1	-0.24688625054792
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/104	116/9376	0.777188328912467	ALDOA	-0.255727264773956
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/104	120/9376	0.751282051282051	JUN	-0.290403384586901
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/104	134/9376	0.672789896670494	PPP1CB	-0.404028237022532
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/104	138/9376	0.653288740245262	PPP1CB	-0.434544349054086
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/104	143/9376	0.630446476600323	ACTN4	-0.471617101254049
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/104	144/9376	0.626068376068376	CTNNB1	-0.478895923397239
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/104	144/9376	0.626068376068376	PSMA6	-0.478895923397239
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/104	150/9376	0.601025641025641	CTNNB1	-0.521674353359579
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/104	154/9376	0.585414585414585	UGP2	-0.549385783656882
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/104	155/9376	0.581637717121588	CTNNB1	-0.556217896842541
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	1/104	157/9376	0.574228319451249	DUSP5	-0.569770929049284
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/104	166/9376	0.543095458758109	PPP1CB	-0.629021224768021
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/104	195/9376	0.46232741617357	ACTB	-0.80353685430959
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	1/104	235/9376	0.383633387888707	ACTB	-1.01342538468789
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	1/104	250/9376	0.360615384615385	CLTC	-1.08519441687783
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/104	254/9376	0.354936402180497	PDGFA	-1.10379889570801
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/104	298/9376	0.302529685080021	IL10RB	-1.29584890926671