ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003725	double-stranded RNA binding	10/174	75/18639	0.133333333333333	14.2827586206897	1.90427033373932e-09	6.73008334170056e-07
GO:0140662	ATP-dependent protein folding chaperone	8/174	40/18639	0.2	21.4241379310345	2.92612319204372e-09	6.73008334170056e-07
GO:0045296	cadherin binding	17/174	334/18639	0.0508982035928144	5.45225067107165	1.63190779998922e-08	2.50225862665014e-06
GO:0140297	DNA-binding transcription factor binding	20/174	488/18639	0.040983606557377	4.39019219898248	3.20456308073061e-08	2.98027422094899e-06
GO:0044183	protein folding chaperone	9/174	75/18639	0.12	12.8544827586207	3.23942850103151e-08	2.98027422094899e-06
GO:0097718	disordered domain specific binding	6/174	28/18639	0.214285714285714	22.9544334975369	1.92875362359491e-07	1.47871111142276e-05
GO:0031072	heat shock protein binding	10/174	131/18639	0.0763358778625954	8.17715188207423	4.22879058143793e-07	2.77891952494492e-05
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	18/174	484/18639	0.0371900826446281	3.98382730122542	6.76242491126158e-07	3.88839432397541e-05
GO:0001216	DNA-binding transcription activator activity	18/174	491/18639	0.0366598778004073	3.92703139265398	8.31503884704222e-07	4.2499087440438e-05
GO:0031625	ubiquitin protein ligase binding	14/174	302/18639	0.0463576158940397	4.96585978533912	9.75201408051294e-07	4.27389975900592e-05
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	15/174	349/18639	0.0429799426934097	4.60404110265784	1.02201950758837e-06	4.27389975900592e-05
GO:0051082	unfolded protein binding	9/174	121/18639	0.0743801652892562	7.96765460245084	2.01887001051387e-06	7.34645879607588e-05
GO:0044389	ubiquitin-like protein ligase binding	14/174	322/18639	0.0434782608695652	4.65742128935532	2.07617313802144e-06	7.34645879607588e-05
GO:0004857	enzyme inhibitor activity	14/174	416/18639	0.0336538461538462	3.60502320954907	3.74674852476862e-05	0.00123107451528112
GO:1990841	promoter-specific chromatin binding	6/174	68/18639	0.0882352941176471	9.45182555780933	4.11501348628749e-05	0.00126193746912817
GO:0060590	ATPase regulator activity	5/174	49/18639	0.102040816326531	10.9306826178747	9.15367456333663e-05	0.00259827602458745
GO:0046332	SMAD binding	6/174	79/18639	0.0759493670886076	8.1357485814055	9.60232443869275e-05	0.00259827602458745
GO:0001671	ATPase activator activity	4/174	27/18639	0.148148148148148	15.8697318007663	0.000108866579071242	0.00278214590959841
GO:0004860	protein kinase inhibitor activity	6/174	84/18639	0.0714285714285714	7.65147783251232	0.000135127395419808	0.00327150536279535
GO:0016887	ATP hydrolysis activity	13/174	417/18639	0.0311750599520384	3.3394939221037	0.000153110037389988	0.00352153085996972
GO:0008187	poly-pyrimidine tract binding	4/174	30/18639	0.133333333333333	14.2827586206897	0.000166328030849161	0.00364337591383877
GO:0019210	kinase inhibitor activity	6/174	90/18639	0.0666666666666667	7.14137931034483	0.00019765713044384	0.0041328309092803
GO:0140311	protein sequestering activity	4/174	33/18639	0.121212121212121	12.9843260188088	0.000242995016627145	0.00465740448535361
GO:0140416	transcription regulator inhibitor activity	4/174	33/18639	0.121212121212121	12.9843260188088	0.000242995016627145	0.00465740448535361
GO:0051087	protein-folding chaperone binding	7/174	134/18639	0.0522388059701493	5.59585692228513	0.000265774799447121	0.00489025630982703
GO:1990226	histone methyltransferase binding	3/174	17/18639	0.176470588235294	18.9036511156187	0.000493813971927259	0.00873670873409766
GO:0003714	transcription corepressor activity	8/174	204/18639	0.0392156862745098	4.20081135902637	0.000674815206534122	0.011196700223891
GO:0048156	tau protein binding	4/174	43/18639	0.0930232558139535	9.96471531676023	0.000681538274497711	0.011196700223891
GO:0030291	protein serine/threonine kinase inhibitor activity	4/174	46/18639	0.0869565217391304	9.31484257871064	0.00088182237367674	0.0139875273065966
GO:0051117	ATPase binding	5/174	84/18639	0.0595238095238095	6.3762315270936	0.00113976440253887	0.017476387505596
GO:0003727	single-stranded RNA binding	5/174	89/18639	0.0561797752808989	6.0180162727625	0.00147623386745811	0.0219054057751849
GO:0140313	molecular sequestering activity	4/174	55/18639	0.0727272727272727	7.79059561128527	0.00172686152487791	0.0226829321982281
GO:0044325	transmembrane transporter binding	6/174	136/18639	0.0441176470588235	4.72591277890467	0.00175472835203702	0.0226829321982281
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	3/174	26/18639	0.115384615384615	12.3600795755968	0.0017751859981222	0.0226829321982281
GO:0050750	low-density lipoprotein particle receptor binding	3/174	26/18639	0.115384615384615	12.3600795755968	0.0017751859981222	0.0226829321982281
GO:0070412	R-SMAD binding	3/174	26/18639	0.115384615384615	12.3600795755968	0.0017751859981222	0.0226829321982281
GO:0023026	MHC class II protein complex binding	3/174	27/18639	0.111111111111111	11.9022988505747	0.00198347592550357	0.0246594304251795
GO:0070566	adenylyltransferase activity	3/174	30/18639	0.1	10.7120689655172	0.00269728384898078	0.0326513308034515
GO:0019887	protein kinase regulator activity	8/174	255/18639	0.0313725490196078	3.3606490872211	0.00277510046250794	0.0327319541731706
GO:0070325	lipoprotein particle receptor binding	3/174	31/18639	0.0967741935483871	10.3665183537264	0.00296596584257093	0.0341086071895657
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/174	10/18639	0.2	21.4241379310345	0.00371192225899536	0.0397089357939039
GO:0030957	Tat protein binding	2/174	10/18639	0.2	21.4241379310345	0.00371192225899536	0.0397089357939039
GO:0050815	phosphoserine residue binding	2/174	10/18639	0.2	21.4241379310345	0.00371192225899536	0.0397089357939039
GO:0000175	3'-5'-RNA exonuclease activity	3/174	35/18639	0.0857142857142857	9.18177339901478	0.00420245156798315	0.0439347209380057
GO:0001221	transcription coregulator binding	5/174	115/18639	0.0434782608695652	4.65742128935532	0.0044976506438045	0.0450904533173165
GO:0050998	nitric-oxide synthase binding	2/174	11/18639	0.181818181818182	19.4764890282132	0.00450904533173165	0.0450904533173165
GO:0023023	MHC protein complex binding	3/174	37/18639	0.0810810810810811	8.68546132339236	0.00492153302705599	0.0481681955839522
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	3/174	38/18639	0.0789473684210526	8.45689655172414	0.00530714711817289	0.0504853241531967
GO:0004859	phospholipase inhibitor activity	2/174	12/18639	0.166666666666667	17.8534482758621	0.00537778452936226	0.0504853241531967
GO:0019207	kinase regulator activity	8/174	287/18639	0.0278745644599303	2.98594256878529	0.00563743020647742	0.0518643578995922
GO:0003735	structural constituent of ribosome	6/174	175/18639	0.0342857142857143	3.67270935960591	0.00607340623037617	0.0526453250361354
GO:0004532	RNA exonuclease activity	3/174	40/18639	0.075	8.03405172413793	0.0061316290912513	0.0526453250361354
GO:0043021	ribonucleoprotein complex binding	6/174	177/18639	0.0338983050847458	3.6312098188194	0.00641055014246196	0.0526453250361354
GO:0033192	calmodulin-dependent protein phosphatase activity	4/174	81/18639	0.0493827160493827	5.28991060025543	0.00698685777433283	0.0526453250361354
GO:0140791	histone H2AXS140 phosphatase activity	4/174	81/18639	0.0493827160493827	5.28991060025543	0.00698685777433283	0.0526453250361354
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	4/174	81/18639	0.0493827160493827	5.28991060025543	0.00698685777433283	0.0526453250361354
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	4/174	81/18639	0.0493827160493827	5.28991060025543	0.00698685777433283	0.0526453250361354
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	4/174	81/18639	0.0493827160493827	5.28991060025543	0.00698685777433283	0.0526453250361354
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	4/174	81/18639	0.0493827160493827	5.28991060025543	0.00698685777433283	0.0526453250361354
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	4/174	81/18639	0.0493827160493827	5.28991060025543	0.00698685777433283	0.0526453250361354
GO:1990439	MAP kinase serine/threonine phosphatase activity	4/174	81/18639	0.0493827160493827	5.28991060025543	0.00698685777433283	0.0526453250361354
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	4/174	82/18639	0.0487804878048781	5.22539949537426	0.00729272106892524	0.0526453250361354
GO:0033549	MAP kinase phosphatase activity	4/174	82/18639	0.0487804878048781	5.22539949537426	0.00729272106892524	0.0526453250361354
GO:0044548	S100 protein binding	2/174	14/18639	0.142857142857143	15.3029556650246	0.00732456696154927	0.0526453250361354
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	4/174	83/18639	0.0481927710843374	5.16244287494807	0.00760729101769681	0.0538362133560082
GO:0017018	myosin phosphatase activity	4/174	84/18639	0.0476190476190476	5.10098522167488	0.0079306673484547	0.0552743481861995
GO:0140776	protein-containing complex destabilizing activity	2/174	15/18639	0.133333333333333	14.2827586206897	0.00839988646009448	0.0575853070606248
GO:0140597	protein carrier chaperone	6/174	188/18639	0.0319148936170213	3.41874541452678	0.00851261060896192	0.0575853070606248
GO:0140789	histone phosphatase activity	5/174	136/18639	0.0367647058823529	3.93826064908722	0.00902829836398498	0.0601886557598999
GO:0055102	lipase inhibitor activity	2/174	16/18639	0.125	13.3900862068966	0.0095413741365463	0.0618637091519685
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	4/174	89/18639	0.0449438202247191	4.81441301821	0.00968301534552551	0.0618637091519685
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	4/174	89/18639	0.0449438202247191	4.81441301821	0.00968301534552551	0.0618637091519685
GO:0140793	histone H2AXY142 phosphatase activity	4/174	90/18639	0.0444444444444444	4.76091954022989	0.01006122795398	0.0633995186141208
GO:0030544	Hsp70 protein binding	3/174	51/18639	0.0588235294117647	6.30121703853955	0.0119955448535809	0.0745669004411785
GO:0004725	protein tyrosine phosphatase activity	4/174	98/18639	0.0408163265306122	4.37227304714989	0.0134343146977707	0.0800037171036641
GO:0000510	H3-H4 histone complex chaperone activity	5/174	151/18639	0.033112582781457	3.54704270381366	0.0137397688069336	0.0800037171036641
GO:0140584	chromatin extrusion motor activity	5/174	151/18639	0.033112582781457	3.54704270381366	0.0137397688069336	0.0800037171036641
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	5/174	151/18639	0.033112582781457	3.54704270381366	0.0137397688069336	0.0800037171036641
GO:0140849	ATP-dependent H2AZ histone chaperone activity	5/174	151/18639	0.033112582781457	3.54704270381366	0.0137397688069336	0.0800037171036641
GO:0015616	DNA translocase activity	5/174	152/18639	0.0328947368421053	3.52370689655172	0.0141028853574901	0.0800904600548822
GO:0140674	ATP-dependent histone chaperone activity	5/174	152/18639	0.0328947368421053	3.52370689655172	0.0141028853574901	0.0800904600548822
GO:0061775	cohesin loader activity	5/174	153/18639	0.0326797385620915	3.50067613252197	0.0144724067026247	0.0811866717464311
GO:0043024	ribosomal small subunit binding	2/174	20/18639	0.1	10.7120689655172	0.0147429932165897	0.0817081551762801
GO:0004722	protein serine/threonine phosphatase activity	4/174	103/18639	0.0388349514563107	4.16002678272514	0.015867855364841	0.0868953984265102
GO:0070182	DNA polymerase binding	2/174	21/18639	0.0952380952380952	10.2019704433498	0.016195971480567	0.0876487868360097
GO:0140658	ATP-dependent chromatin remodeler activity	5/174	158/18639	0.0316455696202532	3.38989524225229	0.0164176868563611	0.0878155343479779
GO:0008408	3'-5' exonuclease activity	3/174	58/18639	0.0517241379310345	5.54072532699168	0.0169532547410645	0.0896378986309159
GO:0003689	DNA clamp loader activity	5/174	160/18639	0.03125	3.34752155172414	0.0172422080007751	0.0901297236404153
GO:0036002	pre-mRNA binding	3/174	59/18639	0.0508474576271186	5.44681472822911	0.0177415263514394	0.0916977766478888
GO:0003712	transcription coregulator activity	10/174	495/18639	0.0202020202020202	2.16405433646813	0.0180531559427126	0.0922716859294199
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	3/174	60/18639	0.05	5.35603448275862	0.0185499472458627	0.0937689640999655
GO:0140713	histone chaperone activity	5/174	164/18639	0.0304878048780488	3.26587468460892	0.0189726769263688	0.0948633846318439
GO:0004721	phosphoprotein phosphatase activity	5/174	175/18639	0.0285714285714286	3.06059113300493	0.0243094253257794	0.120240168278049
GO:0008266	poly(U) RNA binding	2/174	27/18639	0.0740740740740741	7.93486590038314	0.0261018510121723	0.127732462399992
GO:0097110	scaffold protein binding	3/174	70/18639	0.0428571428571429	4.59088669950739	0.0277458339763151	0.13434824872742
GO:0140104	molecular carrier activity	6/174	249/18639	0.0240963855421687	2.58122143747403	0.0296392761065097	0.142021531343692
GO:0042826	histone deacetylase binding	4/174	127/18639	0.031496062992126	3.37387998913929	0.0312895177887741	0.147529987951618
GO:0035925	mRNA 3'-UTR AU-rich region binding	2/174	30/18639	0.0666666666666667	7.14137931034483	0.031766488608975	0.147529987951618
GO:0031490	chromatin DNA binding	4/174	128/18639	0.03125	3.34752155172414	0.0320717365112214	0.147529987951618
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	4/174	128/18639	0.03125	3.34752155172414	0.0320717365112214	0.147529987951618
GO:0003724	RNA helicase activity	3/174	77/18639	0.038961038961039	4.17353336318854	0.0353812374566845	0.159821913699772
GO:0043425	bHLH transcription factor binding	2/174	32/18639	0.0625	6.69504310344828	0.0357862111110359	0.159821913699772
GO:0070717	poly-purine tract binding	2/174	32/18639	0.0625	6.69504310344828	0.0357862111110359	0.159821913699772
GO:0008186	ATP-dependent activity, acting on RNA	3/174	79/18639	0.0379746835443038	4.06787429070275	0.0377418316288742	0.165888631483642
GO:0071889	14-3-3 protein binding	2/174	33/18639	0.0606060606060606	6.49216300940439	0.03786588327344	0.165888631483642
GO:0016779	nucleotidyltransferase activity	4/174	136/18639	0.0294117647058824	3.15060851926978	0.038741674611546	0.168124248314256
GO:0016922	nuclear receptor binding	4/174	137/18639	0.0291970802919708	3.12761137679336	0.0396270995343024	0.169571506100654
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	6/174	268/18639	0.0223880597014925	2.39822439526505	0.0401641122269012	0.169571506100654
GO:0001618	virus receptor activity	3/174	81/18639	0.037037037037037	3.96743295019157	0.0401810742716767	0.169571506100654
GO:0140272	exogenous protein binding	3/174	82/18639	0.0365853658536585	3.9190496215307	0.0414299990768445	0.173252723412259
GO:0004527	exonuclease activity	3/174	84/18639	0.0357142857142857	3.82573891625616	0.0439860426024183	0.182284500874887
GO:0001217	DNA-binding transcription repressor activity	6/174	278/18639	0.0215827338129496	2.31195733068717	0.0465480762077746	0.191179598710503
GO:0008094	ATP-dependent activity, acting on DNA	5/174	210/18639	0.0238095238095238	2.55049261083744	0.0473277644075656	0.192661695818409
GO:0004386	helicase activity	4/174	155/18639	0.0258064516129032	2.76440489432703	0.0575278406813144	0.23196969433139
GO:0008307	structural constituent of muscle	2/174	42/18639	0.0476190476190476	5.10098522167488	0.0584967055270462	0.23196969433139
GO:0048487	beta-tubulin binding	2/174	42/18639	0.0476190476190476	5.10098522167488	0.0584967055270462	0.23196969433139
GO:0001223	transcription coactivator binding	2/174	44/18639	0.0454545454545455	4.86912225705329	0.0635072258640879	0.249686529038294
GO:0043130	ubiquitin binding	3/174	100/18639	0.03	3.21362068965517	0.0671362418031832	0.26171755279207
GO:0030276	clathrin binding	2/174	46/18639	0.0434782608695652	4.65742128935532	0.0686569422854972	0.265396583624611
GO:0015631	tubulin binding	7/174	385/18639	0.0181818181818182	1.94764890282132	0.0697950306801426	0.267547617607213
GO:0008013	beta-catenin binding	3/174	106/18639	0.0283018867924528	3.03171763175016	0.0769935669126006	0.292702816361953
GO:0019888	protein phosphatase regulator activity	3/174	107/18639	0.0280373831775701	3.00338382210764	0.0786952484767899	0.296719789338716
GO:0003743	translation initiation factor activity	2/174	51/18639	0.0392156862745098	4.20081135902637	0.0820958550231346	0.302340868760369
GO:0042393	histone binding	5/174	247/18639	0.0202429149797571	2.1684350132626	0.0821665739736423	0.302340868760369
GO:0005080	protein kinase C binding	2/174	52/18639	0.0384615384615385	4.12002652519894	0.0848739211132626	0.302340868760369
GO:0005200	structural constituent of cytoskeleton	3/174	112/18639	0.0267857142857143	2.86930418719212	0.0874468453399613	0.302340868760369
GO:0043022	ribosome binding	3/174	112/18639	0.0267857142857143	2.86930418719212	0.0874468453399613	0.302340868760369
GO:0005544	calcium-dependent phospholipid binding	2/174	53/18639	0.0377358490566038	4.04229017566688	0.0876802474056057	0.302340868760369
GO:0140296	general transcription initiation factor binding	2/174	53/18639	0.0377358490566038	4.04229017566688	0.0876802474056057	0.302340868760369
GO:0008140	cAMP response element binding protein binding	1/174	10/18639	0.1	10.7120689655172	0.0895477934844535	0.302340868760369
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/174	10/18639	0.1	10.7120689655172	0.0895477934844535	0.302340868760369
GO:0042975	peroxisome proliferator activated receptor binding	1/174	10/18639	0.1	10.7120689655172	0.0895477934844535	0.302340868760369
GO:0099122	RNA polymerase II C-terminal domain binding	1/174	10/18639	0.1	10.7120689655172	0.0895477934844535	0.302340868760369
GO:0015485	cholesterol binding	2/174	54/18639	0.037037037037037	3.96743295019157	0.0905140715561262	0.302340868760369
GO:0098632	cell-cell adhesion mediator activity	2/174	55/18639	0.0363636363636364	3.89529780564263	0.093374642843085	0.302340868760369
GO:0019208	phosphatase regulator activity	3/174	117/18639	0.0256410256410256	2.74668435013263	0.0965897722041216	0.302340868760369
GO:1990782	protein tyrosine kinase binding	3/174	117/18639	0.0256410256410256	2.74668435013263	0.0965897722041216	0.302340868760369
GO:0005536	D-glucose binding	1/174	11/18639	0.0909090909090909	9.73824451410658	0.0980516682997257	0.302340868760369
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/174	11/18639	0.0909090909090909	9.73824451410658	0.0980516682997257	0.302340868760369
GO:0019107	myristoyltransferase activity	1/174	11/18639	0.0909090909090909	9.73824451410658	0.0980516682997257	0.302340868760369
GO:0032050	clathrin heavy chain binding	1/174	11/18639	0.0909090909090909	9.73824451410658	0.0980516682997257	0.302340868760369
GO:0043522	leucine zipper domain binding	1/174	11/18639	0.0909090909090909	9.73824451410658	0.0980516682997257	0.302340868760369
GO:0045294	alpha-catenin binding	1/174	11/18639	0.0909090909090909	9.73824451410658	0.0980516682997257	0.302340868760369
GO:0048407	platelet-derived growth factor binding	1/174	11/18639	0.0909090909090909	9.73824451410658	0.0980516682997257	0.302340868760369
GO:0097493	structural molecule activity conferring elasticity	1/174	11/18639	0.0909090909090909	9.73824451410658	0.0980516682997257	0.302340868760369
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/174	11/18639	0.0909090909090909	9.73824451410658	0.0980516682997257	0.302340868760369
GO:0140031	phosphorylation-dependent protein binding	1/174	11/18639	0.0909090909090909	9.73824451410658	0.0980516682997257	0.302340868760369
GO:0140537	transcription regulator activator activity	1/174	11/18639	0.0909090909090909	9.73824451410658	0.0980516682997257	0.302340868760369
GO:0016504	peptidase activator activity	2/174	57/18639	0.0350877192982456	3.75862068965517	0.0991730811617716	0.302340868760369
GO:0003730	mRNA 3'-UTR binding	5/174	262/18639	0.0190839694656489	2.04428797051856	0.0993307777712823	0.302340868760369
GO:0032182	ubiquitin-like protein binding	3/174	120/18639	0.025	2.67801724137931	0.10225521621414	0.302340868760369
GO:0003697	single-stranded DNA binding	3/174	121/18639	0.0247933884297521	2.65588486748361	0.104172683720753	0.302340868760369
GO:0004540	RNA nuclease activity	3/174	121/18639	0.0247933884297521	2.65588486748361	0.104172683720753	0.302340868760369
GO:0001786	phosphatidylserine binding	2/174	59/18639	0.0338983050847458	3.6312098188194	0.10506978343508	0.302340868760369
GO:0045309	protein phosphorylated amino acid binding	2/174	59/18639	0.0338983050847458	3.6312098188194	0.10506978343508	0.302340868760369
GO:0070063	RNA polymerase binding	2/174	59/18639	0.0338983050847458	3.6312098188194	0.10506978343508	0.302340868760369
GO:0070888	E-box binding	2/174	59/18639	0.0338983050847458	3.6312098188194	0.10506978343508	0.302340868760369
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	3/174	122/18639	0.0245901639344262	2.63411531938949	0.106104373594881	0.302340868760369
GO:0004126	cytidine deaminase activity	1/174	12/18639	0.0833333333333333	8.92672413793103	0.106476566824304	0.302340868760369
GO:0005095	GTPase inhibitor activity	1/174	12/18639	0.0833333333333333	8.92672413793103	0.106476566824304	0.302340868760369
GO:0035497	cAMP response element binding	1/174	12/18639	0.0833333333333333	8.92672413793103	0.106476566824304	0.302340868760369
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/174	12/18639	0.0833333333333333	8.92672413793103	0.106476566824304	0.302340868760369
GO:0016791	phosphatase activity	5/174	273/18639	0.0183150183150183	1.96191739295188	0.112976925325118	0.31253657056963
GO:0004535	poly(A)-specific ribonuclease activity	1/174	13/18639	0.0769230769230769	8.24005305039788	0.114823218317973	0.31253657056963
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/174	13/18639	0.0769230769230769	8.24005305039788	0.114823218317973	0.31253657056963
GO:0008035	high-density lipoprotein particle binding	1/174	13/18639	0.0769230769230769	8.24005305039788	0.114823218317973	0.31253657056963
GO:0071837	HMG box domain binding	1/174	13/18639	0.0769230769230769	8.24005305039788	0.114823218317973	0.31253657056963
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/174	13/18639	0.0769230769230769	8.24005305039788	0.114823218317973	0.31253657056963
GO:0140666	annealing activity	1/174	13/18639	0.0769230769230769	8.24005305039788	0.114823218317973	0.31253657056963
GO:0005507	copper ion binding	2/174	63/18639	0.0317460317460317	3.40065681444992	0.117135742799531	0.316955539339908
GO:0003779	actin binding	7/174	443/18639	0.0158013544018059	1.69265198100724	0.121781223205199	0.322246484944723
GO:0005161	platelet-derived growth factor receptor binding	1/174	14/18639	0.0714285714285714	7.65147783251232	0.12309234534539	0.322246484944723
GO:0005545	1-phosphatidylinositol binding	1/174	14/18639	0.0714285714285714	7.65147783251232	0.12309234534539	0.322246484944723
GO:0034236	protein kinase A catalytic subunit binding	1/174	14/18639	0.0714285714285714	7.65147783251232	0.12309234534539	0.322246484944723
GO:0070742	C2H2 zinc finger domain binding	1/174	14/18639	0.0714285714285714	7.65147783251232	0.12309234534539	0.322246484944723
GO:0019843	rRNA binding	2/174	65/18639	0.0307692307692308	3.29602122015915	0.123294307283199	0.322246484944723
GO:0000774	adenyl-nucleotide exchange factor activity	1/174	15/18639	0.0666666666666667	7.14137931034483	0.131284663837197	0.331686838854326
GO:0031386	protein tag activity	1/174	15/18639	0.0666666666666667	7.14137931034483	0.131284663837197	0.331686838854326
GO:0042809	nuclear vitamin D receptor binding	1/174	15/18639	0.0666666666666667	7.14137931034483	0.131284663837197	0.331686838854326
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/174	15/18639	0.0666666666666667	7.14137931034483	0.131284663837197	0.331686838854326
GO:0141047	molecular tag activity	1/174	15/18639	0.0666666666666667	7.14137931034483	0.131284663837197	0.331686838854326
GO:0046982	protein heterodimerization activity	6/174	369/18639	0.016260162601626	1.74179983179142	0.132196746431228	0.331686838854326
GO:0051015	actin filament binding	4/174	209/18639	0.0191387559808612	2.05015673981191	0.132234758195806	0.331686838854326
GO:0032934	sterol binding	2/174	68/18639	0.0294117647058824	3.15060851926978	0.132674735541731	0.331686838854326
GO:0002020	protease binding	3/174	136/18639	0.0220588235294118	2.36295638945233	0.134548793592602	0.333981282548249
GO:0002039	p53 binding	2/174	69/18639	0.0289855072463768	3.10494752623688	0.135837106581231	0.333981282548249
GO:0003688	DNA replication origin binding	1/174	16/18639	0.0625	6.69504310344828	0.139400883150573	0.333981282548249
GO:0005159	insulin-like growth factor receptor binding	1/174	16/18639	0.0625	6.69504310344828	0.139400883150573	0.333981282548249
GO:0008142	oxysterol binding	1/174	16/18639	0.0625	6.69504310344828	0.139400883150573	0.333981282548249
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/174	16/18639	0.0625	6.69504310344828	0.139400883150573	0.333981282548249
GO:0030275	LRR domain binding	1/174	16/18639	0.0625	6.69504310344828	0.139400883150573	0.333981282548249
GO:0070411	I-SMAD binding	1/174	16/18639	0.0625	6.69504310344828	0.139400883150573	0.333981282548249
GO:0140767	enzyme-substrate adaptor activity	3/174	139/18639	0.0215827338129496	2.31195733068717	0.140958616453631	0.335963541806581
GO:0032183	SUMO binding	1/174	17/18639	0.0588235294117647	6.30121703853955	0.147441706129245	0.346036657242106
GO:0048038	quinone binding	1/174	17/18639	0.0588235294117647	6.30121703853955	0.147441706129245	0.346036657242106
GO:0051787	misfolded protein binding	1/174	17/18639	0.0588235294117647	6.30121703853955	0.147441706129245	0.346036657242106
GO:0043539	protein serine/threonine kinase activator activity	2/174	73/18639	0.0273972602739726	2.9348134152102	0.148648639374123	0.347098345746684
GO:0048029	monosaccharide binding	2/174	74/18639	0.027027027027027	2.89515377446412	0.151889184986234	0.348720006902213
GO:0140098	catalytic activity, acting on RNA	6/174	387/18639	0.0155038759689922	1.6607858861267	0.154697203483209	0.348720006902213
GO:0019003	GDP binding	2/174	75/18639	0.0266666666666667	2.85655172413793	0.155143687532137	0.348720006902213
GO:0031690	adrenergic receptor binding	1/174	18/18639	0.0555555555555556	5.95114942528736	0.155407829162943	0.348720006902213
GO:0034185	apolipoprotein binding	1/174	18/18639	0.0555555555555556	5.95114942528736	0.155407829162943	0.348720006902213
GO:0070064	proline-rich region binding	1/174	18/18639	0.0555555555555556	5.95114942528736	0.155407829162943	0.348720006902213
GO:0098641	cadherin binding involved in cell-cell adhesion	1/174	18/18639	0.0555555555555556	5.95114942528736	0.155407829162943	0.348720006902213
GO:1990381	ubiquitin-specific protease binding	1/174	18/18639	0.0555555555555556	5.95114942528736	0.155407829162943	0.348720006902213
GO:0098631	cell adhesion mediator activity	2/174	76/18639	0.0263157894736842	2.81896551724138	0.158411608596896	0.353734659973651
GO:0061134	peptidase regulator activity	4/174	226/18639	0.0176991150442478	1.89594140982606	0.161363800222272	0.358586222716159
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/174	20/18639	0.05	5.35603448275862	0.171118729037363	0.377699645497191
GO:0048306	calcium-dependent protein binding	2/174	80/18639	0.025	2.67801724137931	0.171607012845463	0.377699645497191
GO:0051020	GTPase binding	5/174	315/18639	0.0158730158730159	1.70032840722496	0.172526041459968	0.377914186055168
GO:0030971	receptor tyrosine kinase binding	2/174	81/18639	0.0246913580246914	2.64495530012771	0.174934251796698	0.381373250362469
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/174	21/18639	0.0476190476190476	5.10098522167488	0.178864866915203	0.384475882154174
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/174	21/18639	0.0476190476190476	5.10098522167488	0.178864866915203	0.384475882154174
GO:0072542	protein phosphatase activator activity	1/174	21/18639	0.0476190476190476	5.10098522167488	0.178864866915203	0.384475882154174
GO:0008135	translation factor activity, RNA binding	2/174	83/18639	0.0240963855421687	2.58122143747403	0.181619352126685	0.388580939433838
GO:0180051	translation factor activity	2/174	84/18639	0.0238095238095238	2.55049261083744	0.184976262115082	0.390036147442025
GO:0008649	rRNA methyltransferase activity	1/174	22/18639	0.0454545454545455	4.86912225705329	0.18653902703749	0.390036147442025
GO:0033691	sialic acid binding	1/174	22/18639	0.0454545454545455	4.86912225705329	0.18653902703749	0.390036147442025
GO:0061133	endopeptidase activator activity	1/174	22/18639	0.0454545454545455	4.86912225705329	0.18653902703749	0.390036147442025
GO:0070034	telomerase RNA binding	1/174	22/18639	0.0454545454545455	4.86912225705329	0.18653902703749	0.390036147442025
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	2/174	86/18639	0.0232558139534884	2.49117882919006	0.191716482296256	0.398684206351366
GO:0070577	lysine-acetylated histone binding	1/174	23/18639	0.0434782608695652	4.65742128935532	0.194141874397187	0.398684206351366
GO:0099186	structural constituent of postsynapse	1/174	23/18639	0.0434782608695652	4.65742128935532	0.194141874397187	0.398684206351366
GO:0140102	catalytic activity, acting on a rRNA	1/174	23/18639	0.0434782608695652	4.65742128935532	0.194141874397187	0.398684206351366
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/174	24/18639	0.0416666666666667	4.46336206896552	0.201674067878863	0.406886277299461
GO:0019957	C-C chemokine binding	1/174	24/18639	0.0416666666666667	4.46336206896552	0.201674067878863	0.406886277299461
GO:0035035	histone acetyltransferase binding	1/174	24/18639	0.0416666666666667	4.46336206896552	0.201674067878863	0.406886277299461
GO:0140033	acetylation-dependent protein binding	1/174	24/18639	0.0416666666666667	4.46336206896552	0.201674067878863	0.406886277299461
GO:0140097	catalytic activity, acting on DNA	5/174	336/18639	0.0148809523809524	1.5940578817734	0.206079852139332	0.41112256301138
GO:0072341	modified amino acid binding	2/174	91/18639	0.021978021978022	2.35430087154225	0.208700277622679	0.41112256301138
GO:0008483	transaminase activity	1/174	25/18639	0.04	4.2848275862069	0.209136260314484	0.41112256301138
GO:0019211	phosphatase activator activity	1/174	25/18639	0.04	4.2848275862069	0.209136260314484	0.41112256301138
GO:0042974	nuclear retinoic acid receptor binding	1/174	25/18639	0.04	4.2848275862069	0.209136260314484	0.41112256301138
GO:0120020	cholesterol transfer activity	1/174	25/18639	0.04	4.2848275862069	0.209136260314484	0.41112256301138
GO:0043178	alcohol binding	2/174	92/18639	0.0217391304347826	2.32871064467766	0.212116454043949	0.415206676000922
GO:0051219	phosphoprotein binding	2/174	93/18639	0.021505376344086	2.30367074527253	0.215538142004004	0.416750566225085
GO:0008143	poly(A) binding	1/174	26/18639	0.0384615384615385	4.12002652519894	0.216529098538685	0.416750566225085
GO:0034237	protein kinase A regulatory subunit binding	1/174	26/18639	0.0384615384615385	4.12002652519894	0.216529098538685	0.416750566225085
GO:0050681	nuclear androgen receptor binding	1/174	26/18639	0.0384615384615385	4.12002652519894	0.216529098538685	0.416750566225085
GO:0016410	N-acyltransferase activity	2/174	94/18639	0.0212765957446809	2.27916360968452	0.218964943749463	0.419682808853138
GO:0004867	serine-type endopeptidase inhibitor activity	2/174	95/18639	0.0210526315789474	2.2551724137931	0.222396468390842	0.424491184480446
GO:0004364	glutathione transferase activity	1/174	27/18639	0.037037037037037	3.96743295019157	0.223853223443551	0.42550612720675
GO:0019789	SUMO transferase activity	1/174	28/18639	0.0357142857142857	3.82573891625616	0.231109270032893	0.435697804160372
GO:0051019	mitogen-activated protein kinase binding	1/174	28/18639	0.0357142857142857	3.82573891625616	0.231109270032893	0.435697804160372
GO:0106222	lncRNA binding	1/174	29/18639	0.0344827586206897	3.69381688466112	0.238297867476032	0.447416404240714
GO:0016769	transferase activity, transferring nitrogenous groups	1/174	30/18639	0.0333333333333333	3.57068965517241	0.245419639161104	0.455213846831079
GO:0033612	receptor serine/threonine kinase binding	1/174	30/18639	0.0333333333333333	3.57068965517241	0.245419639161104	0.455213846831079
GO:0098918	structural constituent of synapse	1/174	30/18639	0.0333333333333333	3.57068965517241	0.245419639161104	0.455213846831079
GO:0061135	endopeptidase regulator activity	3/174	184/18639	0.016304347826087	1.74653298350825	0.246711809978947	0.455772821647853
GO:1901981	phosphatidylinositol phosphate binding	3/174	185/18639	0.0162162162162162	1.73709226467847	0.249206231427527	0.45853946582665
GO:0042578	phosphoric ester hydrolase activity	5/174	363/18639	0.0137741046831956	1.47549159304645	0.252038610326294	0.461903429283247
GO:0008017	microtubule binding	4/174	276/18639	0.0144927536231884	1.55247376311844	0.257759243995871	0.464189486468367
GO:0030515	snoRNA binding	1/174	32/18639	0.03125	3.34752155172414	0.259465170220017	0.464189486468367
GO:0051059	NF-kappaB binding	1/174	32/18639	0.03125	3.34752155172414	0.259465170220017	0.464189486468367
GO:0071813	lipoprotein particle binding	1/174	32/18639	0.03125	3.34752155172414	0.259465170220017	0.464189486468367
GO:0071814	protein-lipid complex binding	1/174	32/18639	0.03125	3.34752155172414	0.259465170220017	0.464189486468367
GO:0120015	sterol transfer activity	1/174	32/18639	0.03125	3.34752155172414	0.259465170220017	0.464189486468367
GO:0000149	SNARE binding	2/174	106/18639	0.0188679245283019	2.02114508783344	0.260349755453997	0.464189486468367
GO:0019239	deaminase activity	1/174	33/18639	0.0303030303030303	3.24608150470219	0.266390147937097	0.471050843676835
GO:0019956	chemokine binding	1/174	33/18639	0.0303030303030303	3.24608150470219	0.266390147937097	0.471050843676835
GO:0005496	steroid binding	2/174	108/18639	0.0185185185185185	1.98371647509579	0.267270152607943	0.471050843676835
GO:0031267	small GTPase binding	4/174	283/18639	0.0141342756183746	1.51407335201657	0.27214341802195	0.477809054542355
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1/174	34/18639	0.0294117647058824	3.15060851926978	0.273250736685831	0.477929045153925
GO:1902936	phosphatidylinositol bisphosphate binding	2/174	111/18639	0.018018018018018	1.93010251630941	0.27764942725257	0.483783092940083
GO:0061631	ubiquitin conjugating enzyme activity	1/174	35/18639	0.0285714285714286	3.06059113300493	0.28004753173107	0.486120243759593
GO:0000993	RNA polymerase II complex binding	1/174	36/18639	0.0277777777777778	2.97557471264368	0.286781122866245	0.490406381109563
GO:0005484	SNAP receptor activity	1/174	36/18639	0.0277777777777778	2.97557471264368	0.286781122866245	0.490406381109563
GO:0045505	dynein intermediate chain binding	1/174	36/18639	0.0277777777777778	2.97557471264368	0.286781122866245	0.490406381109563
GO:0055106	ubiquitin-protein transferase regulator activity	1/174	36/18639	0.0277777777777778	2.97557471264368	0.286781122866245	0.490406381109563
GO:0035401	histone H3Y41 kinase activity	2/174	115/18639	0.0173913043478261	1.86296851574213	0.291473804255501	0.494752582869116
GO:0140801	histone H2AXY142 kinase activity	2/174	115/18639	0.0173913043478261	1.86296851574213	0.291473804255501	0.494752582869116
GO:0042887	amide transmembrane transporter activity	1/174	38/18639	0.0263157894736842	2.81896551724138	0.300061025522575	0.50559733238236
GO:0043531	ADP binding	1/174	38/18639	0.0263157894736842	2.81896551724138	0.300061025522575	0.50559733238236
GO:0001664	G protein-coupled receptor binding	4/174	297/18639	0.0134680134680135	1.44270289097875	0.301297053404806	0.505827169949674
GO:0004518	nuclease activity	3/174	209/18639	0.0143540669856459	1.53761755485893	0.309925770007226	0.518421288012088
GO:0030331	nuclear estrogen receptor binding	1/174	40/18639	0.025	2.67801724137931	0.313095055462541	0.519941247338516
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	1/174	40/18639	0.025	2.67801724137931	0.313095055462541	0.519941247338516
GO:0001530	lipopolysaccharide binding	1/174	41/18639	0.024390243902439	2.61269974768713	0.31952128592383	0.523693574222533
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	1/174	41/18639	0.024390243902439	2.61269974768713	0.31952128592383	0.523693574222533
GO:0061650	ubiquitin-like protein conjugating enzyme activity	1/174	41/18639	0.024390243902439	2.61269974768713	0.31952128592383	0.523693574222533
GO:0005543	phospholipid binding	6/174	497/18639	0.0120724346076459	1.293207520988	0.319908465992461	0.523693574222533
GO:0019894	kinesin binding	1/174	42/18639	0.0238095238095238	2.55049261083744	0.32588773910424	0.525994245571756
GO:0031492	nucleosomal DNA binding	1/174	42/18639	0.0238095238095238	2.55049261083744	0.32588773910424	0.525994245571756
GO:0043175	RNA polymerase core enzyme binding	1/174	42/18639	0.0238095238095238	2.55049261083744	0.32588773910424	0.525994245571756
GO:0051879	Hsp90 protein binding	1/174	42/18639	0.0238095238095238	2.55049261083744	0.32588773910424	0.525994245571756
GO:0008200	ion channel inhibitor activity	1/174	43/18639	0.0232558139534884	2.49117882919006	0.332194967872098	0.534299598675403
GO:0001046	core promoter sequence-specific DNA binding	1/174	44/18639	0.0227272727272727	2.43456112852665	0.338443520011819	0.538674729836533
GO:0016248	channel inhibitor activity	1/174	44/18639	0.0227272727272727	2.43456112852665	0.338443520011819	0.538674729836533
GO:0043014	alpha-tubulin binding	1/174	44/18639	0.0227272727272727	2.43456112852665	0.338443520011819	0.538674729836533
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	2/174	130/18639	0.0153846153846154	1.64801061007958	0.342895032930866	0.538674729836533
GO:0004715	non-membrane spanning protein tyrosine kinase activity	1/174	45/18639	0.0222222222222222	2.38045977011494	0.344633938270381	0.538674729836533
GO:0051539	4 iron, 4 sulfur cluster binding	1/174	45/18639	0.0222222222222222	2.38045977011494	0.344633938270381	0.538674729836533
GO:0141110	transporter inhibitor activity	1/174	45/18639	0.0222222222222222	2.38045977011494	0.344633938270381	0.538674729836533
GO:0005504	fatty acid binding	1/174	47/18639	0.0212765957446809	2.27916360968452	0.356842519220665	0.538674729836533
GO:0061749	forked DNA-dependent helicase activity	1/174	47/18639	0.0212765957446809	2.27916360968452	0.356842519220665	0.538674729836533
GO:1990518	single-stranded 3'-5' DNA helicase activity	1/174	47/18639	0.0212765957446809	2.27916360968452	0.356842519220665	0.538674729836533
GO:0009378	four-way junction helicase activity	1/174	48/18639	0.0208333333333333	2.23168103448276	0.362861742631573	0.538674729836533
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	1/174	48/18639	0.0208333333333333	2.23168103448276	0.362861742631573	0.538674729836533
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/174	48/18639	0.0208333333333333	2.23168103448276	0.362861742631573	0.538674729836533
GO:0036121	double-stranded DNA helicase activity	1/174	48/18639	0.0208333333333333	2.23168103448276	0.362861742631573	0.538674729836533
GO:0043138	3'-5' DNA helicase activity	1/174	48/18639	0.0208333333333333	2.23168103448276	0.362861742631573	0.538674729836533
GO:0019838	growth factor binding	2/174	136/18639	0.0147058823529412	1.57530425963489	0.363159012070654	0.538674729836533
GO:0001222	transcription corepressor binding	1/174	49/18639	0.0204081632653061	2.18613652357495	0.368824953689725	0.538674729836533
GO:0005004	GPI-linked ephrin receptor activity	1/174	49/18639	0.0204081632653061	2.18613652357495	0.368824953689725	0.538674729836533
GO:0005008	hepatocyte growth factor receptor activity	1/174	49/18639	0.0204081632653061	2.18613652357495	0.368824953689725	0.538674729836533
GO:0005009	insulin receptor activity	1/174	49/18639	0.0204081632653061	2.18613652357495	0.368824953689725	0.538674729836533
GO:0005011	macrophage colony-stimulating factor receptor activity	1/174	49/18639	0.0204081632653061	2.18613652357495	0.368824953689725	0.538674729836533
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/174	49/18639	0.0204081632653061	2.18613652357495	0.368824953689725	0.538674729836533
GO:0005020	stem cell factor receptor activity	1/174	49/18639	0.0204081632653061	2.18613652357495	0.368824953689725	0.538674729836533
GO:0008288	boss receptor activity	1/174	49/18639	0.0204081632653061	2.18613652357495	0.368824953689725	0.538674729836533
GO:0036332	placental growth factor receptor activity	1/174	49/18639	0.0204081632653061	2.18613652357495	0.368824953689725	0.538674729836533
GO:0038062	protein tyrosine kinase collagen receptor activity	1/174	49/18639	0.0204081632653061	2.18613652357495	0.368824953689725	0.538674729836533
GO:0060175	brain-derived neurotrophic factor receptor activity	1/174	49/18639	0.0204081632653061	2.18613652357495	0.368824953689725	0.538674729836533
GO:0030295	protein kinase activator activity	2/174	139/18639	0.0143884892086331	1.54130488712478	0.373204600766814	0.538674729836533
GO:0070851	growth factor receptor binding	2/174	139/18639	0.0143884892086331	1.54130488712478	0.373204600766814	0.538674729836533
GO:0005006	epidermal growth factor receptor activity	1/174	50/18639	0.02	2.14241379310345	0.374732670637438	0.538674729836533
GO:0005007	fibroblast growth factor receptor activity	1/174	50/18639	0.02	2.14241379310345	0.374732670637438	0.538674729836533
GO:0005017	platelet-derived growth factor receptor activity	1/174	50/18639	0.02	2.14241379310345	0.374732670637438	0.538674729836533
GO:0005019	platelet-derived growth factor beta-receptor activity	1/174	50/18639	0.02	2.14241379310345	0.374732670637438	0.538674729836533
GO:0015605	organophosphate ester transmembrane transporter activity	1/174	50/18639	0.02	2.14241379310345	0.374732670637438	0.538674729836533
GO:0004713	protein tyrosine kinase activity	2/174	140/18639	0.0142857142857143	1.53029556650246	0.376539190974798	0.538674729836533
GO:0005010	insulin-like growth factor receptor activity	1/174	51/18639	0.0196078431372549	2.10040567951318	0.380585406949724	0.538674729836533
GO:0005021	vascular endothelial growth factor receptor activity	1/174	51/18639	0.0196078431372549	2.10040567951318	0.380585406949724	0.538674729836533
GO:0005030	neurotrophin receptor activity	1/174	51/18639	0.0196078431372549	2.10040567951318	0.380585406949724	0.538674729836533
GO:0016830	carbon-carbon lyase activity	1/174	51/18639	0.0196078431372549	2.10040567951318	0.380585406949724	0.538674729836533
GO:0019903	protein phosphatase binding	2/174	144/18639	0.0138888888888889	1.48778735632184	0.389803640051503	0.541678274104088
GO:0004864	protein phosphatase inhibitor activity	1/174	53/18639	0.0188679245283019	2.02114508783344	0.392127967992742	0.541678274104088
GO:0005003	ephrin receptor activity	1/174	53/18639	0.0188679245283019	2.02114508783344	0.392127967992742	0.541678274104088
GO:0005005	transmembrane-ephrin receptor activity	1/174	53/18639	0.0188679245283019	2.02114508783344	0.392127967992742	0.541678274104088
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/174	53/18639	0.0188679245283019	2.02114508783344	0.392127967992742	0.541678274104088
GO:0038064	collagen receptor activity	1/174	53/18639	0.0188679245283019	2.02114508783344	0.392127967992742	0.541678274104088
GO:0051018	protein kinase A binding	1/174	53/18639	0.0188679245283019	2.02114508783344	0.392127967992742	0.541678274104088
GO:1901505	carbohydrate derivative transmembrane transporter activity	1/174	53/18639	0.0188679245283019	2.02114508783344	0.392127967992742	0.541678274104088
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	1/174	54/18639	0.0185185185185185	1.98371647509579	0.397818796227395	0.546258645565975
GO:0017069	snRNA binding	1/174	54/18639	0.0185185185185185	1.98371647509579	0.397818796227395	0.546258645565975
GO:0019209	kinase activator activity	2/174	148/18639	0.0135135135135135	1.44757688723206	0.402942743804251	0.551647804017724
GO:0019212	phosphatase inhibitor activity	1/174	56/18639	0.0178571428571429	1.91286945812808	0.409042022354263	0.558336291640834
GO:0042277	peptide binding	3/174	249/18639	0.0120481927710843	1.29061071873702	0.411405276289796	0.559900671873686
GO:0015932	nucleobase-containing compound transmembrane transporter activity	1/174	57/18639	0.0175438596491228	1.87931034482759	0.414575396304129	0.56255068525044
GO:0017116	single-stranded DNA helicase activity	1/174	58/18639	0.0172413793103448	1.84690844233056	0.420057254072027	0.566646149188071
GO:0061980	regulatory RNA binding	1/174	58/18639	0.0172413793103448	1.84690844233056	0.420057254072027	0.566646149188071
GO:0015459	potassium channel regulator activity	1/174	59/18639	0.0169491525423729	1.8156049094097	0.425488072531284	0.571179910998622
GO:0003713	transcription coactivator activity	3/174	256/18639	0.01171875	1.25532058189655	0.428799957400641	0.571179910998622
GO:0001098	basal transcription machinery binding	1/174	60/18639	0.0166666666666667	1.78534482758621	0.430868324166352	0.571179910998622
GO:0001099	basal RNA polymerase II transcription machinery binding	1/174	60/18639	0.0166666666666667	1.78534482758621	0.430868324166352	0.571179910998622
GO:0004714	transmembrane receptor protein tyrosine kinase activity	1/174	60/18639	0.0166666666666667	1.78534482758621	0.430868324166352	0.571179910998622
GO:0098531	ligand-modulated transcription factor activity	1/174	60/18639	0.0166666666666667	1.78534482758621	0.430868324166352	0.571179910998622
GO:0015026	coreceptor activity	1/174	61/18639	0.0163934426229508	1.75607687959299	0.436198477112962	0.573289427062749
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	1/174	61/18639	0.0163934426229508	1.75607687959299	0.436198477112962	0.573289427062749
GO:0019905	syntaxin binding	1/174	61/18639	0.0163934426229508	1.75607687959299	0.436198477112962	0.573289427062749
GO:0004866	endopeptidase inhibitor activity	2/174	161/18639	0.0124223602484472	1.33069179695866	0.444678709029399	0.581114222027056
GO:0005178	integrin binding	2/174	161/18639	0.0124223602484472	1.33069179695866	0.444678709029399	0.581114222027056
GO:0038024	cargo receptor activity	1/174	65/18639	0.0153846153846154	1.64801061007958	0.457027314742625	0.593877301642959
GO:0120013	lipid transfer activity	1/174	65/18639	0.0153846153846154	1.64801061007958	0.457027314742625	0.593877301642959
GO:0016874	ligase activity	2/174	167/18639	0.0119760479041916	1.28288251084039	0.463395114162468	0.600252458035995
GO:0008173	RNA methyltransferase activity	1/174	67/18639	0.0149253731343284	1.59881626351004	0.467152999949752	0.600252458035995
GO:0016500	protein-hormone receptor activity	1/174	67/18639	0.0149253731343284	1.59881626351004	0.467152999949752	0.600252458035995
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1/174	67/18639	0.0149253731343284	1.59881626351004	0.467152999949752	0.600252458035995
GO:0030414	peptidase inhibitor activity	2/174	169/18639	0.0118343195266272	1.26770046929198	0.469552038834739	0.601625478979578
GO:0005525	GTP binding	4/174	378/18639	0.0105820105820106	1.13355227148331	0.471234433910703	0.601625478979578
GO:0140223	general transcription initiation factor activity	1/174	68/18639	0.0147058823529412	1.57530425963489	0.472145212851365	0.601625478979578
GO:0140030	modification-dependent protein binding	2/174	173/18639	0.0115606936416185	1.23838947578234	0.481739364994071	0.61089139027804
GO:0030695	GTPase regulator activity	5/174	489/18639	0.0102249488752556	1.09530357520626	0.482072988415062	0.61089139027804
GO:0060589	nucleoside-triphosphatase regulator activity	5/174	490/18639	0.0102040816326531	1.09306826178747	0.483862986012647	0.611475202103894
GO:0030246	carbohydrate binding	3/174	280/18639	0.0107142857142857	1.14772167487685	0.486918676615097	0.613650934912177
GO:0005518	collagen binding	1/174	72/18639	0.0138888888888889	1.48778735632184	0.491653297548138	0.617924909486731
GO:0035091	phosphatidylinositol binding	3/174	284/18639	0.0105633802816901	1.1315565808645	0.496336039803307	0.622110567600876
GO:0003678	DNA helicase activity	1/174	74/18639	0.0135135135135135	1.44757688723206	0.501136813683856	0.623034957552902
GO:0003684	damaged DNA binding	1/174	74/18639	0.0135135135135135	1.44757688723206	0.501136813683856	0.623034957552902
GO:0031491	nucleosome binding	1/174	74/18639	0.0135135135135135	1.44757688723206	0.501136813683856	0.623034957552902
GO:0051536	iron-sulfur cluster binding	1/174	76/18639	0.0131578947368421	1.40948275862069	0.510444406974661	0.632896030211169
GO:0051540	metal cluster binding	1/174	77/18639	0.012987012987013	1.39117778772951	0.515033248928354	0.63378510122869
GO:0019001	guanyl nucleotide binding	4/174	400/18639	0.01	1.07120689655172	0.515294843172891	0.63378510122869
GO:0032561	guanyl ribonucleotide binding	4/174	400/18639	0.01	1.07120689655172	0.515294843172891	0.63378510122869
GO:0019199	transmembrane receptor protein kinase activity	1/174	78/18639	0.0128205128205128	1.37334217506631	0.51957932234105	0.637350635405022
GO:0031406	carboxylic acid binding	2/174	187/18639	0.0106951871657754	1.14567582518901	0.523013656042489	0.639464697154861
GO:0033293	monocarboxylic acid binding	1/174	79/18639	0.0126582278481013	1.35595809690092	0.524083023537788	0.639464697154861
GO:0043177	organic acid binding	2/174	189/18639	0.0105820105820106	1.13355227148331	0.528729043750237	0.643426878637854
GO:0019902	phosphatase binding	2/174	190/18639	0.0105263157894737	1.12758620689655	0.531569417294053	0.645176601465077
GO:0001540	amyloid-beta binding	1/174	83/18639	0.0120481927710843	1.29061071873702	0.541681905564199	0.653999151074886
GO:0005254	chloride channel activity	1/174	83/18639	0.0120481927710843	1.29061071873702	0.541681905564199	0.653999151074886
GO:0016209	antioxidant activity	1/174	86/18639	0.0116279069767442	1.24558941459503	0.554455042724484	0.667668376055661
GO:0004896	cytokine receptor activity	1/174	96/18639	0.0104166666666667	1.11584051724138	0.594529849328724	0.714056738097162
GO:0003924	GTPase activity	3/174	331/18639	0.00906344410876133	0.970882383581623	0.599886778525364	0.718614370108508
GO:0005253	monoatomic anion channel activity	1/174	103/18639	0.00970873786407767	1.04000669568129	0.620429161444101	0.741291985102042
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	2/174	229/18639	0.00873362445414847	0.935551874717663	0.6331138411206	0.754487997190352
GO:0004843	cysteine-type deubiquitinase activity	1/174	108/18639	0.00925925925925926	0.991858237547893	0.6379150864489	0.758245322394041
GO:0101005	deubiquitinase activity	1/174	115/18639	0.00869565217391304	0.931484257871064	0.661057735249151	0.783728242821159
GO:0009055	electron transfer activity	1/174	116/18639	0.00862068965517241	0.923454221165279	0.664241494376049	0.785478373812294
GO:0015108	chloride transmembrane transporter activity	1/174	121/18639	0.00826446280991736	0.885294955827871	0.679719742307109	0.801720721695565
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/174	122/18639	0.00819672131147541	0.878038439796495	0.682729179872643	0.803210799850169
GO:0019783	ubiquitin-like protein peptidase activity	1/174	127/18639	0.0078740157480315	0.843469997284822	0.697359808206713	0.818330387181347
GO:0005179	hormone activity	1/174	132/18639	0.00757575757575758	0.811520376175549	0.711319458634734	0.830474494852735
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	1/174	132/18639	0.00757575757575758	0.811520376175549	0.711319458634734	0.830474494852735
GO:0015297	antiporter activity	1/174	135/18639	0.00740740740740741	0.793486590038314	0.719385968456336	0.837765937949151
GO:0005096	GTPase activator activity	2/174	271/18639	0.00738007380073801	0.790558595241125	0.722468763412328	0.839231391842603
GO:0020037	heme binding	1/174	142/18639	0.00704225352112676	0.754371053909665	0.737346846251367	0.854356547293776
GO:0019955	cytokine binding	1/174	144/18639	0.00694444444444444	0.74389367816092	0.74226525642085	0.857894517471334
GO:0008509	monoatomic anion transmembrane transporter activity	1/174	149/18639	0.00671140939597315	0.718930803054848	0.75416431082135	0.869462613979501
GO:0046906	tetrapyrrole binding	1/174	152/18639	0.00657894736842105	0.704741379310345	0.761039876843921	0.87519585837051
GO:0005506	iron ion binding	1/174	154/18639	0.00649350649350649	0.695588893864756	0.765517023378282	0.878149203875336
GO:0140375	immune receptor activity	1/174	156/18639	0.00641025641025641	0.686671087533156	0.769910759386517	0.880992411238303
GO:0099106	ion channel regulator activity	1/174	160/18639	0.00625	0.669504310344828	0.778454151949616	0.888558089074003
GO:0008083	growth factor activity	1/174	162/18639	0.00617283950617284	0.661238825031928	0.782606813938513	0.891086966365633
GO:0015103	inorganic anion transmembrane transporter activity	1/174	165/18639	0.00606060606060606	0.649216300940439	0.788691133786649	0.895797337140391
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	1/174	167/18639	0.00598802395209581	0.641441255420194	0.792652980426526	0.89587944823863
GO:0005201	extracellular matrix structural constituent	1/174	168/18639	0.00595238095238095	0.63762315270936	0.794606119307307	0.89587944823863
GO:0016247	channel regulator activity	1/174	168/18639	0.00595238095238095	0.63762315270936	0.794606119307307	0.89587944823863
GO:0141108	transporter regulator activity	1/174	170/18639	0.00588235294117647	0.630121703853955	0.798457687931052	0.898020871511696
GO:0008201	heparin binding	1/174	172/18639	0.00581395348837209	0.622794707297514	0.802237438854128	0.900071272860729
GO:0005319	lipid transporter activity	1/174	178/18639	0.00561797752808989	0.60180162727625	0.813158978546644	0.910104939492595
GO:0016853	isomerase activity	1/174	180/18639	0.00555555555555556	0.595114942528736	0.816664530852572	0.911809913087823
GO:0008234	cysteine-type peptidase activity	1/174	187/18639	0.0053475935828877	0.572837912594505	0.828426837845616	0.922703015518119
GO:0061630	ubiquitin protein ligase activity	2/174	353/18639	0.0056657223796034	0.606916088697861	0.844804936540987	0.925973359372043
GO:0016755	aminoacyltransferase activity	3/174	496/18639	0.00604838709677419	0.647907397107898	0.84551855026818	0.925973359372043
GO:0141003	histone H2AX kinase activity	2/174	354/18639	0.00564971751412429	0.605201636469901	0.845938826628733	0.925973359372043
GO:0016829	lyase activity	1/174	200/18639	0.005	0.535603448275862	0.848315982538628	0.925973359372043
GO:0140996	histone H3 kinase activity	2/174	357/18639	0.00560224089635854	0.600115908432339	0.849295751560828	0.925973359372043
GO:0035173	histone kinase activity	2/174	360/18639	0.00555555555555556	0.595114942528736	0.852586393343943	0.925973359372043
GO:0008168	methyltransferase activity	1/174	204/18639	0.00490196078431373	0.525101419878296	0.853961378373169	0.925973359372043
GO:0005516	calmodulin binding	1/174	207/18639	0.00483091787439614	0.517491254372814	0.858057877406346	0.925973359372043
GO:0061659	ubiquitin-like protein ligase activity	2/174	372/18639	0.00537634408602151	0.575917686318131	0.865107352943891	0.925973359372043
GO:0016741	transferase activity, transferring one-carbon groups	1/174	215/18639	0.00465116279069767	0.498235765838011	0.868431799634335	0.925973359372043
GO:0005085	guanyl-nucleotide exchange factor activity	1/174	230/18639	0.00434782608695652	0.465742128935532	0.885893211790186	0.925973359372043
GO:0005539	glycosaminoglycan binding	1/174	242/18639	0.00413223140495868	0.442647477913936	0.898186947853528	0.925973359372043
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	1/174	243/18639	0.00411522633744856	0.440825883354619	0.899149902197904	0.925973359372043
GO:0004676	3-phosphoinositide-dependent protein kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:0004711	ribosomal protein S6 kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:0035175	histone H3S10 kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:0035979	histone H2AXS139 kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:0044022	histone H3S28 kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:0044023	histone H4S1 kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:0044024	histone H2AS1 kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:0044025	histone H2BS14 kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:0072354	histone H3T3 kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:0072371	histone H2AS121 kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:0072518	Rho-dependent protein serine/threonine kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:0140823	histone H2BS36 kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:0140855	histone H3S57 kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:0140995	histone H2A kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:0140997	histone H4 kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:0140998	histone H2B kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:1990244	histone H2AT120 kinase activity	1/174	245/18639	0.00408163265306122	0.437227304714989	0.901048728063391	0.925973359372043
GO:0004677	DNA-dependent protein kinase activity	1/174	246/18639	0.0040650406504065	0.435449957947855	0.901984768148036	0.925973359372043
GO:0140857	histone H3T45 kinase activity	1/174	246/18639	0.0040650406504065	0.435449957947855	0.901984768148036	0.925973359372043
GO:0033218	amide binding	1/174	247/18639	0.00404858299595142	0.43368700265252	0.902912004071607	0.925973359372043
GO:0035402	histone H3T11 kinase activity	1/174	247/18639	0.00404858299595142	0.43368700265252	0.902912004071607	0.925973359372043
GO:0035403	histone H3T6 kinase activity	1/174	247/18639	0.00404858299595142	0.43368700265252	0.902912004071607	0.925973359372043
GO:0004679	AMP-activated protein kinase activity	1/174	248/18639	0.00403225806451613	0.431938264738598	0.903830518169668	0.925973359372043
GO:0004674	protein serine/threonine kinase activity	2/174	433/18639	0.0046189376443418	0.494783785936131	0.914971394670012	0.935304092329345
GO:0008514	organic anion transmembrane transporter activity	1/174	269/18639	0.00371747211895911	0.398218177156775	0.921242546245267	0.937847183217044
GO:0004842	ubiquitin-protein transferase activity	2/174	449/18639	0.0044543429844098	0.477152292450657	0.924858520548024	0.937847183217044
GO:0005126	cytokine receptor binding	1/174	275/18639	0.00363636363636364	0.389529780564263	0.925614393870735	0.937847183217044
GO:1901681	sulfur compound binding	1/174	275/18639	0.00363636363636364	0.389529780564263	0.925614393870735	0.937847183217044
GO:0015291	secondary active transmembrane transporter activity	1/174	287/18639	0.00348432055749129	0.373242821098162	0.933647246641404	0.943907106494606
GO:0019787	ubiquitin-like protein transferase activity	2/174	479/18639	0.00417536534446764	0.44726801526168	0.940556205621083	0.948806698652847
GO:0106310	protein serine kinase activity	1/174	361/18639	0.00277008310249307	0.296733212341198	0.967259510608136	0.97360913540425
GO:0004175	endopeptidase activity	1/174	405/18639	0.00246913580246914	0.264495530012771	0.978517393269903	0.982790394987238
GO:0005216	monoatomic ion channel activity	1/174	448/18639	0.00223214285714286	0.23910868226601	0.98578265029476	0.986961024024342
GO:0022804	active transmembrane transporter activity	1/174	457/18639	0.00218818380743982	0.234399758545235	0.986961024024342	0.986961024024342