ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	120/2228	495/18639	0.242424242424242	2.02807246613351	1.16302522936589e-14	1.39679330046844e-11
GO:0019787	ubiquitin-like protein transferase activity	114/2228	479/18639	0.237995824634656	1.99102521335967	2.07320936240006e-13	1.24496222212123e-10
GO:0016755	aminoacyltransferase activity	115/2228	496/18639	0.231854838709677	1.93965095992355	1.04594219650713e-12	4.18725526001688e-10
GO:0004842	ubiquitin-protein transferase activity	105/2228	449/18639	0.233853006681514	1.95636723138992	5.92009162642344e-12	1.77750751083364e-09
GO:0140297	DNA-binding transcription factor binding	107/2228	488/18639	0.219262295081967	1.83430427200753	2.22525425375126e-10	5.34506071751052e-08
GO:0061659	ubiquitin-like protein ligase activity	86/2228	372/18639	0.231182795698925	1.93402878322812	9.00253107582675e-10	1.80200663701132e-07
GO:0044389	ubiquitin-like protein ligase binding	77/2228	322/18639	0.239130434782609	2.00051713371322	1.35735262073503e-09	2.32882928214682e-07
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	80/2228	349/18639	0.229226361031519	1.91766164419501	5.22807636087283e-09	7.07403089132184e-07
GO:0031625	ubiquitin protein ligase binding	72/2228	302/18639	0.23841059602649	1.99449510742269	5.30110558050762e-09	7.07403089132184e-07
GO:0003713	transcription coactivator activity	63/2228	256/18639	0.24609375	2.05877082865799	1.31583627646461e-08	1.580319368034e-06
GO:0061630	ubiquitin protein ligase activity	79/2228	353/18639	0.223796033994334	1.87223262011687	2.00243563146739e-08	2.18629563035667e-06
GO:0016922	nuclear receptor binding	39/2228	137/18639	0.284671532846715	2.38150480284108	1.36829065759299e-07	1.36943089980765e-05
GO:0003725	double-stranded RNA binding	25/2228	75/18639	0.333333333333333	2.78859964093357	9.88028145439327e-07	9.12786002055871e-05
GO:0003724	RNA helicase activity	25/2228	77/18639	0.324675324675325	2.7161684814288	1.71649382301798e-06	0.000147250648674614
GO:0008186	ATP-dependent activity, acting on RNA	25/2228	79/18639	0.316455696202532	2.64740472240529	2.91001142172554e-06	0.000232994914499492
GO:0043021	ribonucleoprotein complex binding	43/2228	177/18639	0.242937853107345	2.03236922983294	3.63487518531875e-06	0.000272842818597989
GO:0046966	nuclear thyroid hormone receptor binding	13/2228	28/18639	0.464285714285714	3.88412092844319	6.43641164891301e-06	0.000454713552373207
GO:0140098	catalytic activity, acting on RNA	76/2228	387/18639	0.196382428940568	1.642895912488	7.78572926684306e-06	0.000519481158304362
GO:0000175	3'-5'-RNA exonuclease activity	14/2228	35/18639	0.4	3.34631956912029	2.33650564601707e-05	0.00147691751624553
GO:0008135	translation factor activity, RNA binding	24/2228	83/18639	0.289156626506024	2.41902619454479	2.51685699467074e-05	0.00151137262529978
GO:0180051	translation factor activity	24/2228	84/18639	0.285714285714286	2.39022826365735	3.12845067276181e-05	0.00178917583713664
GO:0070063	RNA polymerase binding	19/2228	59/18639	0.322033898305085	2.69407083954599	3.34719863380775e-05	0.00182726616327414
GO:0003735	structural constituent of ribosome	40/2228	175/18639	0.228571428571429	1.91218261092588	3.58423891318261e-05	0.00187159605857927
GO:0008137	NADH dehydrogenase (ubiquinone) activity	15/2228	41/18639	0.365853658536585	3.06065814248807	4.18636056292171e-05	0.00201112761442759
GO:0061650	ubiquitin-like protein conjugating enzyme activity	15/2228	41/18639	0.365853658536585	3.06065814248807	4.18636056292171e-05	0.00201112761442759
GO:0043175	RNA polymerase core enzyme binding	15/2228	42/18639	0.357142857142857	2.98778532957169	5.79675866607053e-05	0.00262106790771058
GO:0035613	RNA stem-loop binding	10/2228	21/18639	0.476190476190476	3.98371377276225	5.89249238203044e-05	0.00262106790771058
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	14/2228	38/18639	0.368421052631579	3.08213644524237	6.87722361650246e-05	0.00294983770122124
GO:0140104	molecular carrier activity	51/2228	249/18639	0.204819277108434	1.71347688780256	7.65523305195199e-05	0.00317032237772219
GO:0003727	single-stranded RNA binding	24/2228	89/18639	0.269662921348315	2.25594577693502	8.67904365655167e-05	0.00346232070976641
GO:0140597	protein carrier chaperone	41/2228	188/18639	0.218085106382979	1.8244561480576	8.9368810993138e-05	0.00346232070976641
GO:0003954	NADH dehydrogenase activity	15/2228	44/18639	0.340909090909091	2.85197690550024	0.000107049124700399	0.00401768746141186
GO:0061631	ubiquitin conjugating enzyme activity	13/2228	35/18639	0.371428571428571	3.10729674275455	0.000113063856279027	0.00403962070273282
GO:0019902	phosphatase binding	41/2228	190/18639	0.215789473684211	1.8052513464991	0.000114360619394601	0.00403962070273282
GO:0005525	GTP binding	70/2228	378/18639	0.185185185185185	1.54922202274087	0.000120708584178732	0.0040566080850305
GO:0061578	K63-linked deubiquitinase activity	8/2228	15/18639	0.533333333333333	4.46175942549372	0.000121596911791089	0.0040566080850305
GO:0004532	RNA exonuclease activity	14/2228	40/18639	0.35	2.92802962298025	0.000130948031335232	0.004250502314422
GO:1990380	K48-linked deubiquitinase activity	9/2228	19/18639	0.473684210526316	3.96274685816876	0.000146972810075685	0.00450624606190428
GO:0001098	basal transcription machinery binding	18/2228	60/18639	0.3	2.50973967684022	0.000150083132786154	0.00450624606190428
GO:0001099	basal RNA polymerase II transcription machinery binding	18/2228	60/18639	0.3	2.50973967684022	0.000150083132786154	0.00450624606190428
GO:0000993	RNA polymerase II complex binding	13/2228	36/18639	0.361111111111111	3.0209829443447	0.000157726895534273	0.00462024393991858
GO:0070411	I-SMAD binding	8/2228	16/18639	0.5	4.18289946140036	0.000217709514426755	0.00622545540063173
GO:0019001	guanyl nucleotide binding	72/2228	400/18639	0.18	1.50584380610413	0.000237529552242663	0.00637705442943528
GO:0032561	guanyl ribonucleotide binding	72/2228	400/18639	0.18	1.50584380610413	0.000237529552242663	0.00637705442943528
GO:0043024	ribosomal small subunit binding	9/2228	20/18639	0.45	3.76460951526032	0.000238940424083753	0.00637705442943528
GO:0061980	regulatory RNA binding	17/2228	58/18639	0.293103448275862	2.45204451185538	0.000309325211792763	0.00807607781224147
GO:0002039	p53 binding	19/2228	69/18639	0.27536231884058	2.30362579033643	0.000342109387721161	0.0086188500399168
GO:0008139	nuclear localization sequence binding	10/2228	25/18639	0.4	3.34631956912029	0.00034759051510263	0.0086188500399168
GO:0003924	GTPase activity	61/2228	331/18639	0.18429003021148	1.54173333622611	0.000364509821379918	0.0086188500399168
GO:0031996	thioesterase binding	6/2228	10/18639	0.6	5.01947935368043	0.000396266227501418	0.0086188500399168
GO:0000510	H3-H4 histone complex chaperone activity	33/2228	151/18639	0.218543046357616	1.82828718180413	0.000398905949571104	0.0086188500399168
GO:0140584	chromatin extrusion motor activity	33/2228	151/18639	0.218543046357616	1.82828718180413	0.000398905949571104	0.0086188500399168
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	33/2228	151/18639	0.218543046357616	1.82828718180413	0.000398905949571104	0.0086188500399168
GO:0140849	ATP-dependent H2AZ histone chaperone activity	33/2228	151/18639	0.218543046357616	1.82828718180413	0.000398905949571104	0.0086188500399168
GO:0140857	histone H3T45 kinase activity	48/2228	246/18639	0.195121951219512	1.63235100932697	0.000400612783340602	0.0086188500399168
GO:0001222	transcription corepressor binding	15/2228	49/18639	0.306122448979592	2.56095885391859	0.000410859246949541	0.0086188500399168
GO:0008187	poly-pyrimidine tract binding	11/2228	30/18639	0.366666666666667	3.06745960502693	0.000431770739628097	0.0086188500399168
GO:0051721	protein phosphatase 2A binding	11/2228	30/18639	0.366666666666667	3.06745960502693	0.000431770739628097	0.0086188500399168
GO:0140713	histone chaperone activity	35/2228	164/18639	0.213414634146341	1.78538391645137	0.000434042973304329	0.0086188500399168
GO:0035403	histone H3T6 kinase activity	48/2228	247/18639	0.194331983805668	1.62574230078718	0.000440726120999721	0.0086188500399168
GO:0140658	ATP-dependent chromatin remodeler activity	34/2228	158/18639	0.215189873417722	1.8002352112356	0.000443689202712476	0.0086188500399168
GO:0015616	DNA translocase activity	33/2228	152/18639	0.217105263157895	1.81625897666068	0.000452112866373654	0.0086188500399168
GO:0140674	ATP-dependent histone chaperone activity	33/2228	152/18639	0.217105263157895	1.81625897666068	0.000452112866373654	0.0086188500399168
GO:0061775	cohesin loader activity	33/2228	153/18639	0.215686274509804	1.80438800295702	0.000511506294845541	0.00959873531421085
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	47/2228	243/18639	0.193415637860082	1.61807633486269	0.000559876954856152	0.00964042648088354
GO:0003689	DNA clamp loader activity	34/2228	160/18639	0.2125	1.77773227109515	0.000564187512691076	0.00964042648088354
GO:0043022	ribosome binding	26/2228	112/18639	0.232142857142857	1.9420604642216	0.00060824009160127	0.00964042648088354
GO:0004676	3-phosphoinositide-dependent protein kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:0004711	ribosomal protein S6 kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:0035175	histone H3S10 kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:0035979	histone H2AXS139 kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:0044022	histone H3S28 kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:0044023	histone H4S1 kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:0044024	histone H2AS1 kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:0044025	histone H2BS14 kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:0072354	histone H3T3 kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:0072371	histone H2AS121 kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:0072518	Rho-dependent protein serine/threonine kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:0140823	histone H2BS36 kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:0140855	histone H3S57 kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:0140995	histone H2A kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:0140997	histone H4 kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:0140998	histone H2B kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:1990244	histone H2AT120 kinase activity	47/2228	245/18639	0.191836734693878	1.60486754845565	0.000674267963692105	0.00964042648088354
GO:0008266	poly(U) RNA binding	10/2228	27/18639	0.37037037037037	3.09844404548175	0.000716352345245357	0.0101216372545844
GO:0004677	DNA-dependent protein kinase activity	47/2228	246/18639	0.191056910569106	1.59834369663266	0.000738900091714825	0.0103188256994128
GO:0019903	protein phosphatase binding	31/2228	144/18639	0.215277777777778	1.80097060143627	0.000768871109777137	0.0105229033667311
GO:0106310	protein serine kinase activity	64/2228	361/18639	0.177285318559557	1.48313332703392	0.00077103704935249	0.0105229033667311
GO:0070990	snRNP binding	6/2228	11/18639	0.545454545454545	4.56316304880039	0.000783531896280243	0.0105732787351974
GO:0035402	histone H3T11 kinase activity	47/2228	247/18639	0.190283400809717	1.59187266952078	0.000808970974832873	0.0106144805137808
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	18/2228	68/18639	0.264705882352941	2.21447618544725	0.000811240810354815	0.0106144805137808
GO:0070717	poly-purine tract binding	11/2228	32/18639	0.34375	2.87574337971275	0.000813099256675967	0.0106144805137808
GO:0035198	miRNA binding	13/2228	42/18639	0.30952380952381	2.58941395229546	0.000875013980098015	0.0112999117214808
GO:0004679	AMP-activated protein kinase activity	47/2228	248/18639	0.189516129032258	1.58545382811143	0.000884867052918411	0.0113055886229257
GO:0008408	3'-5' exonuclease activity	16/2228	58/18639	0.275862068965517	2.3078065993933	0.000959428769954096	0.0121291995022618
GO:0019003	GDP binding	19/2228	75/18639	0.253333333333333	2.11933572710952	0.00105150374582602	0.0131547499868443
GO:0003925	G protein activity	15/2228	54/18639	0.277777777777778	2.32383303411131	0.00126677861756435	0.0156845476257194
GO:0019843	rRNA binding	17/2228	65/18639	0.261538461538462	2.18797817980942	0.0012955259676131	0.0158768029296258
GO:0045296	cadherin binding	59/2228	334/18639	0.176646706586826	1.47779082768037	0.00132106030817277	0.0160261962637929
GO:0004386	helicase activity	32/2228	155/18639	0.206451612903226	1.72713268083628	0.00133948988825271	0.0160872735579151
GO:0061608	nuclear import signal receptor activity	8/2228	20/18639	0.4	3.34631956912029	0.00137127441036928	0.0163059462064703
GO:1990817	poly(A) RNA polymerase activity	6/2228	12/18639	0.5	4.18289946140036	0.00140882971123479	0.01658827924699
GO:0042393	histone binding	46/2228	247/18639	0.186234817813765	1.55800303825438	0.00144869630395718	0.0168920802043939
GO:0003743	translation initiation factor activity	14/2228	51/18639	0.274509803921569	2.2964938219453	0.00205644301027393	0.0235217910032284
GO:0005048	signal sequence binding	14/2228	51/18639	0.274509803921569	2.2964938219453	0.00205644301027393	0.0235217910032284
GO:1990841	promoter-specific chromatin binding	17/2228	68/18639	0.25	2.09144973070018	0.00220197265642865	0.0249487656638756
GO:0097602	cullin family protein binding	9/2228	26/18639	0.346153846153846	2.89585347327717	0.00228004068630664	0.0255918585444324
GO:0009055	electron transfer activity	25/2228	116/18639	0.21551724137931	1.80297390577602	0.0023306947080023	0.0259181883732478
GO:0004535	poly(A)-specific ribonuclease activity	6/2228	13/18639	0.461538461538462	3.86113796436956	0.00235289805942329	0.0259250510951135
GO:0016779	nucleotidyltransferase activity	28/2228	136/18639	0.205882352941176	1.72237036645897	0.00269632797836506	0.0294389991092404
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	15/2228	58/18639	0.258620689655172	2.16356868693122	0.00274869433912449	0.0297403774890857
GO:0051059	NF-kappaB binding	10/2228	32/18639	0.3125	2.61431216337522	0.00312998742653361	0.0332665035333351
GO:0140142	nucleocytoplasmic carrier activity	10/2228	32/18639	0.3125	2.61431216337522	0.00312998742653361	0.0332665035333351
GO:0003746	translation elongation factor activity	7/2228	18/18639	0.388888888888889	3.25336624775583	0.00331658443201316	0.034548235159501
GO:0008308	voltage-gated monoatomic anion channel activity	7/2228	18/18639	0.388888888888889	3.25336624775583	0.00331658443201316	0.034548235159501
GO:0140693	molecular condensate scaffold activity	13/2228	48/18639	0.270833333333333	2.26573720825853	0.00333688199708752	0.034548235159501
GO:0004674	protein serine/threonine kinase activity	71/2228	433/18639	0.163972286374134	1.3717591767179	0.00344627333710059	0.0353758485286992
GO:0003714	transcription corepressor activity	38/2228	204/18639	0.186274509803922	1.55833509346288	0.00354754664806396	0.0361068095281764
GO:0008140	cAMP response element binding protein binding	5/2228	10/18639	0.5	4.18289946140036	0.00364159782609823	0.0367525965474284
GO:0032182	ubiquitin-like protein binding	25/2228	120/18639	0.208333333333333	1.74287477558348	0.00375525593433923	0.0375838531428451
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	15/2228	60/18639	0.25	2.09144973070018	0.00390661006155254	0.0387755263134265
GO:0140311	protein sequestering activity	10/2228	33/18639	0.303030303030303	2.53509058266688	0.00401725239263558	0.0395468862586503
GO:0019783	ubiquitin-like protein peptidase activity	26/2228	127/18639	0.204724409448819	1.71268324403794	0.00405338166086361	0.0395781412577008
GO:0001221	transcription coregulator binding	24/2228	115/18639	0.208695652173913	1.74590586214971	0.00435644207016308	0.0418566954101269
GO:0101005	deubiquitinase activity	24/2228	115/18639	0.208695652173913	1.74590586214971	0.00435644207016308	0.0418566954101269
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	47/2228	268/18639	0.175373134328358	1.46713637825236	0.00443444134681966	0.0422679687105589
GO:0001217	DNA-binding transcription repressor activity	48/2228	278/18639	0.172661870503597	1.44445449026775	0.00551179171313987	0.0521233216337086
GO:0008094	ATP-dependent activity, acting on DNA	38/2228	210/18639	0.180952380952381	1.51381123364965	0.00583869400801145	0.0547055260225855
GO:0061791	GTPase motor activity	11/2228	40/18639	0.275	2.3005947037702	0.00592149740460959	0.0547055260225855
GO:1990606	membrane scission GTPase motor activity	11/2228	40/18639	0.275	2.3005947037702	0.00592149740460959	0.0547055260225855
GO:0019207	kinase regulator activity	49/2228	287/18639	0.170731707317073	1.4283071331611	0.00632444262217909	0.0579821037346342
GO:0035925	mRNA 3'-UTR AU-rich region binding	9/2228	30/18639	0.3	2.50973967684022	0.00671478110315386	0.0610943341279378
GO:0015399	primary active transmembrane transporter activity	31/2228	166/18639	0.186746987951807	1.56228775064351	0.00759428855156427	0.0685769966197646
GO:0140030	modification-dependent protein binding	32/2228	173/18639	0.184971098265896	1.5474310146221	0.00779851795627467	0.0698956721304917
GO:0004843	cysteine-type deubiquitinase activity	22/2228	108/18639	0.203703703703704	1.70414422501496	0.00825295059930535	0.0734206938501164
GO:0051082	unfolded protein binding	24/2228	121/18639	0.198347107438017	1.6593320177456	0.00838966685091358	0.0740881609407883
GO:0045309	protein phosphorylated amino acid binding	14/2228	59/18639	0.23728813559322	1.98510482913915	0.00849402179871475	0.0744621910967622
GO:0050681	nuclear androgen receptor binding	8/2228	26/18639	0.307692307692308	2.57409197624637	0.00883520534670609	0.0763387167006764
GO:0070412	R-SMAD binding	8/2228	26/18639	0.307692307692308	2.57409197624637	0.00883520534670609	0.0763387167006764
GO:0140996	histone H3 kinase activity	58/2228	357/18639	0.162464985994398	1.35914940482477	0.00922142779367217	0.0791066770014305
GO:0035197	siRNA binding	5/2228	12/18639	0.416666666666667	3.48574955116697	0.00931938352216927	0.0793799972349311
GO:0004527	exonuclease activity	18/2228	84/18639	0.214285714285714	1.79267119774301	0.00947782162432154	0.0801610124704941
GO:0016887	ATP hydrolysis activity	66/2228	417/18639	0.158273381294964	1.32408328274544	0.0103319614531455	0.0867740259106838
GO:0035173	histone kinase activity	58/2228	360/18639	0.161111111111111	1.34782315978456	0.0109074891032535	0.0909714889792181
GO:0046332	SMAD binding	17/2228	79/18639	0.215189873417722	1.8002352112356	0.011016509498727	0.0912470890204904
GO:0070403	NAD+ binding	6/2228	17/18639	0.352941176470588	2.95263491392967	0.0111324625357075	0.0914149695584319
GO:0004725	protein tyrosine phosphatase activity	20/2228	98/18639	0.204081632653061	1.70730590261239	0.0111890095962444	0.0914149695584319
GO:0140313	molecular sequestering activity	13/2228	55/18639	0.236363636363636	1.97737065448017	0.0113609060085103	0.092192217001492
GO:0141003	histone H2AX kinase activity	57/2228	354/18639	0.161016949152542	1.347035419773	0.011666137535391	0.0940337663087557
GO:0022853	active monoatomic ion transmembrane transporter activity	23/2228	118/18639	0.194915254237288	1.63062182393573	0.0119556135964066	0.0957246128618955
GO:0031267	small GTPase binding	47/2228	283/18639	0.166077738515901	1.3893729659775	0.0121122669430688	0.0963366397259972
GO:0000049	tRNA binding	17/2228	80/18639	0.2125	1.77773227109515	0.0124734697532089	0.0985568235105517
GO:0051219	phosphoprotein binding	19/2228	93/18639	0.204301075268817	1.7091417154109	0.0130422660532059	0.102377526339218
GO:0044183	protein folding chaperone	16/2228	75/18639	0.213333333333333	1.78470377019749	0.0145285471912011	0.113303799848263
GO:0016504	peptidase activator activity	13/2228	57/18639	0.228070175438596	1.90798922800718	0.0153013868037576	0.118561068072987
GO:0051536	iron-sulfur cluster binding	16/2228	76/18639	0.210526315789474	1.76122082585278	0.0164196608583415	0.126158264537118
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	24/2228	128/18639	0.1875	1.56858729802513	0.0164919629744609	0.126158264537118
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	17/2228	83/18639	0.204819277108434	1.71347688780256	0.0177658209102696	0.135042727298948
GO:0051540	metal cluster binding	16/2228	77/18639	0.207792207792208	1.73834782811443	0.0184950404627788	0.13970153204904
GO:0004722	protein serine/threonine phosphatase activity	20/2228	103/18639	0.194174757281553	1.62442697530111	0.0189342104071541	0.141652095446843
GO:0043998	histone H2A acetyltransferase activity	7/2228	24/18639	0.291666666666667	2.44002468581688	0.0189891651681447	0.141652095446843
GO:0003756	protein disulfide isomerase activity	6/2228	19/18639	0.315789473684211	2.64183123877917	0.0198057131473005	0.145275396743606
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	6/2228	19/18639	0.315789473684211	2.64183123877917	0.0198057131473005	0.145275396743606
GO:0060589	nucleoside-triphosphatase regulator activity	74/2228	490/18639	0.151020408163265	1.26340636793317	0.0199441302649538	0.145275396743606
GO:0001727	lipid kinase activity	10/2228	41/18639	0.24390243902439	2.04043876165871	0.020079696802197	0.145275396743606
GO:0140318	protein transporter activity	10/2228	41/18639	0.24390243902439	2.04043876165871	0.020079696802197	0.145275396743606
GO:0016860	intramolecular oxidoreductase activity	12/2228	53/18639	0.226415094339623	1.89414315233224	0.020468475720102	0.146325234165729
GO:0034212	protein N-acetyltransferase activity	12/2228	53/18639	0.226415094339623	1.89414315233224	0.020468475720102	0.146325234165729
GO:0042277	peptide binding	41/2228	249/18639	0.164658634538153	1.37750102744911	0.0206696650642763	0.146889158237845
GO:0031624	ubiquitin conjugating enzyme binding	8/2228	30/18639	0.266666666666667	2.23087971274686	0.0214904913482709	0.14919121450447
GO:0043995	histone H4K5 acetyltransferase activity	8/2228	30/18639	0.266666666666667	2.23087971274686	0.0214904913482709	0.14919121450447
GO:0043996	histone H4K8 acetyltransferase activity	8/2228	30/18639	0.266666666666667	2.23087971274686	0.0214904913482709	0.14919121450447
GO:0043997	histone H4K12 acetyltransferase activity	8/2228	30/18639	0.266666666666667	2.23087971274686	0.0214904913482709	0.14919121450447
GO:0044390	ubiquitin-like protein conjugating enzyme binding	9/2228	36/18639	0.25	2.09144973070018	0.0229305676213191	0.158273630535657
GO:0005528	FK506 binding	4/2228	10/18639	0.4	3.34631956912029	0.0235917290485875	0.159164745831761
GO:0016303	1-phosphatidylinositol-3-kinase activity	4/2228	10/18639	0.4	3.34631956912029	0.0235917290485875	0.159164745831761
GO:0050815	phosphoserine residue binding	4/2228	10/18639	0.4	3.34631956912029	0.0235917290485875	0.159164745831761
GO:0004402	histone acetyltransferase activity	10/2228	42/18639	0.238095238095238	1.99185688638112	0.0236145865694796	0.159164745831761
GO:0017056	structural constituent of nuclear pore	7/2228	25/18639	0.28	2.3424236983842	0.0237223059982392	0.159164745831761
GO:0005085	guanyl-nucleotide exchange factor activity	38/2228	230/18639	0.165217391304348	1.38217547420186	0.0239422012190015	0.159747687022337
GO:0043539	protein serine/threonine kinase activator activity	15/2228	73/18639	0.205479452054795	1.71899977865768	0.0242989408160159	0.161232198453232
GO:0016004	phospholipase activator activity	6/2228	20/18639	0.3	2.50973967684022	0.0255011635085768	0.166450529205439
GO:0030742	GTP-dependent protein binding	6/2228	20/18639	0.3	2.50973967684022	0.0255011635085768	0.166450529205439
GO:0042288	MHC class I protein binding	6/2228	20/18639	0.3	2.50973967684022	0.0255011635085768	0.166450529205439
GO:0000774	adenyl-nucleotide exchange factor activity	5/2228	15/18639	0.333333333333333	2.78859964093357	0.0260405390578261	0.168143480690587
GO:0042809	nuclear vitamin D receptor binding	5/2228	15/18639	0.333333333333333	2.78859964093357	0.0260405390578261	0.168143480690587
GO:0030695	GTPase regulator activity	73/2228	489/18639	0.149284253578732	1.24888204778007	0.0261937861613184	0.168228541068147
GO:0004721	phosphoprotein phosphatase activity	30/2228	175/18639	0.171428571428571	1.43413695819441	0.0264492248407217	0.168965526775036
GO:0042826	histone deacetylase binding	23/2228	127/18639	0.181102362204724	1.51506594664895	0.0271170198384454	0.172131777278476
GO:0016763	pentosyltransferase activity	11/2228	49/18639	0.224489795918367	1.87803649287363	0.0274395643445145	0.172131777278476
GO:0060590	ATPase regulator activity	11/2228	49/18639	0.224489795918367	1.87803649287363	0.0274395643445145	0.172131777278476
GO:0051087	protein-folding chaperone binding	24/2228	134/18639	0.17910447761194	1.49835204587476	0.0275181525707472	0.172131777278476
GO:0016410	N-acyltransferase activity	18/2228	94/18639	0.191489361702128	1.60196149585546	0.0285047048204883	0.177379018079826
GO:0003697	single-stranded DNA binding	22/2228	121/18639	0.181818181818182	1.52105434960013	0.0289828755817107	0.179424915328013
GO:0008143	poly(A) binding	7/2228	26/18639	0.269230769230769	2.25233047921558	0.0292070272909092	0.179885332186574
GO:0019887	protein kinase regulator activity	41/2228	255/18639	0.16078431372549	1.34508923856796	0.0293785034586532	0.180018278846135
GO:0016651	oxidoreductase activity, acting on NAD(P)H	17/2228	88/18639	0.193181818181818	1.61612024645014	0.0302266721858113	0.184275295914514
GO:0022884	macromolecule transmembrane transporter activity	8/2228	32/18639	0.25	2.09144973070018	0.0311656818754864	0.189040322891208
GO:0035591	signaling adaptor activity	23/2228	129/18639	0.178294573643411	1.49157655212726	0.0319200758793768	0.19067027802391
GO:0001046	core promoter sequence-specific DNA binding	10/2228	44/18639	0.227272727272727	1.90131793700016	0.0319904979774213	0.19067027802391
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	16/2228	82/18639	0.195121951219512	1.63235100932697	0.0320061417819167	0.19067027802391
GO:0051020	GTPase binding	49/2228	315/18639	0.155555555555556	1.30134649910233	0.0320694389349125	0.19067027802391
GO:0140789	histone phosphatase activity	24/2228	136/18639	0.176470588235294	1.47631745696483	0.0322306629053459	0.190684857878426
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	17/2228	89/18639	0.191011235955056	1.59796159199564	0.0333486573069145	0.193256531714702
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	17/2228	89/18639	0.191011235955056	1.59796159199564	0.0333486573069145	0.193256531714702
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	4/2228	11/18639	0.363636363636364	3.04210869920026	0.0336308202567633	0.193256531714702
GO:0010854	adenylate cyclase regulator activity	4/2228	11/18639	0.363636363636364	3.04210869920026	0.0336308202567633	0.193256531714702
GO:0034713	type I transforming growth factor beta receptor binding	4/2228	11/18639	0.363636363636364	3.04210869920026	0.0336308202567633	0.193256531714702
GO:0140537	transcription regulator activator activity	4/2228	11/18639	0.363636363636364	3.04210869920026	0.0336308202567633	0.193256531714702
GO:0140034	methylation-dependent protein binding	15/2228	76/18639	0.197368421052632	1.65114452423698	0.0338282788416989	0.193465537566097
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/2228	16/18639	0.3125	2.61431216337522	0.0342407076809002	0.193976839267741
GO:0034450	ubiquitin-ubiquitin ligase activity	5/2228	16/18639	0.3125	2.61431216337522	0.0342407076809002	0.193976839267741
GO:0008320	protein transmembrane transporter activity	7/2228	27/18639	0.259259259259259	2.16891083183722	0.0354863598465575	0.2000897566935
GO:0019208	phosphatase regulator activity	21/2228	117/18639	0.179487179487179	1.50155365281039	0.0366224771695511	0.202289071058939
GO:0000287	magnesium ion binding	37/2228	230/18639	0.160869565217391	1.34580243540707	0.0366876698685433	0.202289071058939
GO:0140793	histone H2AXY142 phosphatase activity	17/2228	90/18639	0.188888888888889	1.58020646319569	0.0367012402744879	0.202289071058939
GO:0008234	cysteine-type peptidase activity	31/2228	187/18639	0.165775401069519	1.38684367169424	0.0368160851370327	0.202289071058939
GO:0051539	4 iron, 4 sulfur cluster binding	10/2228	45/18639	0.222222222222222	1.85906642728905	0.036877127155621	0.202289071058939
GO:0071889	14-3-3 protein binding	8/2228	33/18639	0.242424242424242	2.02807246613351	0.0369699800146536	0.202289071058939
GO:0042578	phosphoric ester hydrolase activity	55/2228	363/18639	0.151515151515152	1.26754529133344	0.0379612263399719	0.202289071058939
GO:0051117	ATPase binding	16/2228	84/18639	0.19047619047619	1.5934855091049	0.0390628317336553	0.202289071058939
GO:0004407	histone deacetylase activity	6/2228	22/18639	0.272727272727273	2.2815815244002	0.0399188258459355	0.202289071058939
GO:0032931	histone H3K56 acetyltransferase activity	6/2228	22/18639	0.272727272727273	2.2815815244002	0.0399188258459355	0.202289071058939
GO:0033558	protein lysine deacetylase activity	6/2228	22/18639	0.272727272727273	2.2815815244002	0.0399188258459355	0.202289071058939
GO:0043992	histone H3K9 acetyltransferase activity	6/2228	22/18639	0.272727272727273	2.2815815244002	0.0399188258459355	0.202289071058939
GO:0043993	histone H3K18 acetyltransferase activity	6/2228	22/18639	0.272727272727273	2.2815815244002	0.0399188258459355	0.202289071058939
GO:0043994	histone H3K23 acetyltransferase activity	6/2228	22/18639	0.272727272727273	2.2815815244002	0.0399188258459355	0.202289071058939
GO:0043999	histone H2AK5 acetyltransferase activity	6/2228	22/18639	0.272727272727273	2.2815815244002	0.0399188258459355	0.202289071058939
GO:0044012	histone H2AK9 acetyltransferase activity	6/2228	22/18639	0.272727272727273	2.2815815244002	0.0399188258459355	0.202289071058939
GO:0044014	histone H2BK5 acetyltransferase activity	6/2228	22/18639	0.272727272727273	2.2815815244002	0.0399188258459355	0.202289071058939
GO:0044015	histone H2BK12 acetyltransferase activity	6/2228	22/18639	0.272727272727273	2.2815815244002	0.0399188258459355	0.202289071058939
GO:0044016	histone H3K4 acetyltransferase activity	6/2228	22/18639	0.272727272727273	2.2815815244002	0.0399188258459355	0.202289071058939
GO:0044017	histone H3K27 acetyltransferase activity	6/2228	22/18639	0.272727272727273	2.2815815244002	0.0399188258459355	0.202289071058939
GO:0044018	histone H3K36 acetyltransferase activity	6/2228	22/18639	0.272727272727273	2.2815815244002	0.0399188258459355	0.202289071058939
GO:0046972	histone H4K16 acetyltransferase activity	6/2228	22/18639	0.272727272727273	2.2815815244002	0.0399188258459355	0.202289071058939
GO:0140035	ubiquitin-like protein reader activity	6/2228	22/18639	0.272727272727273	2.2815815244002	0.0399188258459355	0.202289071058939
GO:0140908	histone H3K122 acetyltransferase activity	6/2228	22/18639	0.272727272727273	2.2815815244002	0.0399188258459355	0.202289071058939
GO:0140767	enzyme-substrate adaptor activity	24/2228	139/18639	0.172661870503597	1.44445449026775	0.0404063193787842	0.203899115856806
GO:0160215	deacylase activity	13/2228	65/18639	0.2	1.67315978456014	0.0419350767473454	0.210527749393955
GO:0036408	histone H3K14 acetyltransferase activity	7/2228	28/18639	0.25	2.09144973070018	0.0425963722753797	0.210527749393955
GO:0046625	sphingolipid binding	7/2228	28/18639	0.25	2.09144973070018	0.0425963722753797	0.210527749393955
GO:0051537	2 iron, 2 sulfur cluster binding	7/2228	28/18639	0.25	2.09144973070018	0.0425963722753797	0.210527749393955
GO:0141052	histone H3 demethylase activity	7/2228	28/18639	0.25	2.09144973070018	0.0425963722753797	0.210527749393955
GO:0052866	phosphatidylinositol phosphate phosphatase activity	8/2228	34/18639	0.235294117647059	1.96842327595311	0.0434579710001441	0.213307048311071
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	5/2228	17/18639	0.294117647058824	2.46052909494139	0.0438691431580637	0.213307048311071
GO:0032183	SUMO binding	5/2228	17/18639	0.294117647058824	2.46052909494139	0.0438691431580637	0.213307048311071
GO:0051787	misfolded protein binding	5/2228	17/18639	0.294117647058824	2.46052909494139	0.0438691431580637	0.213307048311071
GO:0005527	macrolide binding	4/2228	12/18639	0.333333333333333	2.78859964093357	0.0457865386240603	0.220841899146572
GO:0070410	co-SMAD binding	4/2228	12/18639	0.333333333333333	2.78859964093357	0.0457865386240603	0.220841899146572
GO:0019209	kinase activator activity	25/2228	148/18639	0.168918918918919	1.41314170993255	0.0465071502163249	0.223420349639225
GO:0001784	phosphotyrosine residue binding	10/2228	47/18639	0.212765957446809	1.77995721761717	0.0481471487420022	0.229463196980733
GO:0061733	protein-lysine-acetyltransferase activity	10/2228	47/18639	0.212765957446809	1.77995721761717	0.0481471487420022	0.229463196980733
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	6/2228	23/18639	0.260869565217391	2.18238232768714	0.0487283921772157	0.229501172567985
GO:0044013	histone H2B acetyltransferase activity	6/2228	23/18639	0.260869565217391	2.18238232768714	0.0487283921772157	0.229501172567985
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	6/2228	23/18639	0.260869565217391	2.18238232768714	0.0487283921772157	0.229501172567985
GO:0043130	ubiquitin binding	18/2228	100/18639	0.18	1.50584380610413	0.0490076200950218	0.229914655211411
GO:0019888	protein phosphatase regulator activity	19/2228	107/18639	0.177570093457944	1.48551569657209	0.0495686741420438	0.231309674067865
GO:0004540	RNA nuclease activity	21/2228	121/18639	0.173553719008264	1.4519155155274	0.0501481782460516	0.231309674067865
GO:0031490	chromatin DNA binding	22/2228	128/18639	0.171875	1.43787168985637	0.0502182078943525	0.231309674067865
GO:0010484	histone H3 acetyltransferase activity	7/2228	29/18639	0.241379310344828	2.01933077446914	0.0505655764699547	0.231309674067865
GO:0106222	lncRNA binding	7/2228	29/18639	0.241379310344828	2.01933077446914	0.0505655764699547	0.231309674067865
GO:0010485	histone H4 acetyltransferase activity	8/2228	35/18639	0.228571428571429	1.91218261092588	0.0506531592671511	0.231309674067865
GO:0140566	histone reader activity	8/2228	35/18639	0.228571428571429	1.91218261092588	0.0506531592671511	0.231309674067865
GO:0015631	tubulin binding	57/2228	385/18639	0.148051948051948	1.23857282753153	0.0512021846901696	0.232931150806415
GO:0016791	phosphatase activity	42/2228	273/18639	0.153846153846154	1.28704598812319	0.0514613872944374	0.233226891096677
GO:0008173	RNA methyltransferase activity	13/2228	67/18639	0.194029850746269	1.62321471636432	0.0518858029737919	0.234073916584504
GO:0017069	snRNA binding	11/2228	54/18639	0.203703703703704	1.70414422501496	0.0520380813722419	0.234073916584504
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	10/2228	48/18639	0.208333333333333	1.74287477558348	0.0545634579306557	0.239792203397968
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	5/2228	18/18639	0.277777777777778	2.32383303411131	0.0549571206851826	0.239792203397968
GO:0033192	calmodulin-dependent protein phosphatase activity	15/2228	81/18639	0.185185185185185	1.54922202274087	0.0553059453299227	0.239792203397968
GO:0140791	histone H2AXS140 phosphatase activity	15/2228	81/18639	0.185185185185185	1.54922202274087	0.0553059453299227	0.239792203397968
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	15/2228	81/18639	0.185185185185185	1.54922202274087	0.0553059453299227	0.239792203397968
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	15/2228	81/18639	0.185185185185185	1.54922202274087	0.0553059453299227	0.239792203397968
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	15/2228	81/18639	0.185185185185185	1.54922202274087	0.0553059453299227	0.239792203397968
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	15/2228	81/18639	0.185185185185185	1.54922202274087	0.0553059453299227	0.239792203397968
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	15/2228	81/18639	0.185185185185185	1.54922202274087	0.0553059453299227	0.239792203397968
GO:1990439	MAP kinase serine/threonine phosphatase activity	15/2228	81/18639	0.185185185185185	1.54922202274087	0.0553059453299227	0.239792203397968
GO:0004197	cysteine-type endopeptidase activity	16/2228	88/18639	0.181818181818182	1.52105434960013	0.0564092879098552	0.243696240214878
GO:0048487	beta-tubulin binding	9/2228	42/18639	0.214285714285714	1.79267119774301	0.0568224784526581	0.244601421582947
GO:0030145	manganese ion binding	13/2228	68/18639	0.191176470588235	1.5993439117119	0.0574204050416556	0.246292523053673
GO:0048027	mRNA 5'-UTR binding	6/2228	24/18639	0.25	2.09144973070018	0.0586414678469061	0.24886361443157
GO:0050699	WW domain binding	6/2228	24/18639	0.25	2.09144973070018	0.0586414678469061	0.24886361443157
GO:0060229	lipase activator activity	6/2228	24/18639	0.25	2.09144973070018	0.0586414678469061	0.24886361443157
GO:0032452	histone demethylase activity	7/2228	30/18639	0.233333333333333	1.9520197486535	0.0594145154200324	0.250374852699856
GO:0070566	adenylyltransferase activity	7/2228	30/18639	0.233333333333333	1.9520197486535	0.0594145154200324	0.250374852699856
GO:0097157	pre-mRNA intronic binding	4/2228	13/18639	0.307692307692308	2.57409197624637	0.0600590282630269	0.250454489388525
GO:0140666	annealing activity	4/2228	13/18639	0.307692307692308	2.57409197624637	0.0600590282630269	0.250454489388525
GO:0140852	histone ubiquitin ligase activity	4/2228	13/18639	0.307692307692308	2.57409197624637	0.0600590282630269	0.250454489388525
GO:0033549	MAP kinase phosphatase activity	15/2228	82/18639	0.182926829268293	1.53032907124403	0.0605223192585808	0.251513167576317
GO:0016407	acetyltransferase activity	17/2228	96/18639	0.177083333333333	1.48144355924596	0.0620918345739797	0.256282717253912
GO:0031072	heat shock protein binding	22/2228	131/18639	0.16793893129771	1.40494333054669	0.062096811591081	0.256282717253912
GO:0008080	N-acetyltransferase activity	13/2228	69/18639	0.188405797101449	1.57616501444071	0.0633394153810238	0.260515883125375
GO:0140101	catalytic activity, acting on a tRNA	23/2228	139/18639	0.165467625899281	1.38426888650659	0.0659027655855507	0.27013386166637
GO:0097001	ceramide binding	5/2228	19/18639	0.263157894736842	2.20152603231598	0.0675111948058548	0.274850660887565
GO:0140036	ubiquitin-modified protein reader activity	5/2228	19/18639	0.263157894736842	2.20152603231598	0.0675111948058548	0.274850660887565
GO:0140457	protein demethylase activity	7/2228	31/18639	0.225806451612903	1.88905136966468	0.0691555286067882	0.279839312635108
GO:0004709	MAP kinase kinase kinase activity	6/2228	25/18639	0.24	2.00779174147217	0.0696685715885905	0.279839312635108
GO:0042974	nuclear retinoic acid receptor binding	6/2228	25/18639	0.24	2.00779174147217	0.0696685715885905	0.279839312635108
GO:0047617	fatty acyl-CoA hydrolase activity	6/2228	25/18639	0.24	2.00779174147217	0.0696685715885905	0.279839312635108
GO:0004860	protein kinase inhibitor activity	15/2228	84/18639	0.178571428571429	1.49389266478584	0.0719319978835537	0.287011061322751
GO:0017018	myosin phosphatase activity	15/2228	84/18639	0.178571428571429	1.49389266478584	0.0719319978835537	0.287011061322751
GO:0001223	transcription coactivator binding	9/2228	44/18639	0.204545454545455	1.71118614330015	0.0729399660119513	0.290069202583952
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	35/2228	229/18639	0.152838427947598	1.27861555588657	0.0754898030105621	0.299218658137575
GO:0019992	diacylglycerol binding	4/2228	14/18639	0.285714285714286	2.39022826365735	0.0763978335661423	0.300832124960449
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	4/2228	14/18639	0.285714285714286	2.39022826365735	0.0763978335661423	0.300832124960449
GO:0030515	snoRNA binding	7/2228	32/18639	0.21875	1.83001851436266	0.0797926856915528	0.313173253318807
GO:0005160	transforming growth factor beta receptor binding	6/2228	26/18639	0.230769230769231	1.93056898218478	0.0818070348778948	0.31649121076195
GO:0016289	acyl-CoA hydrolase activity	6/2228	26/18639	0.230769230769231	1.93056898218478	0.0818070348778948	0.31649121076195
GO:0052742	phosphatidylinositol kinase activity	6/2228	26/18639	0.230769230769231	1.93056898218478	0.0818070348778948	0.31649121076195
GO:0120014	phospholipid transfer activity	6/2228	26/18639	0.230769230769231	1.93056898218478	0.0818070348778948	0.31649121076195
GO:0004715	non-membrane spanning protein tyrosine kinase activity	9/2228	45/18639	0.2	1.67315978456014	0.0819556757260338	0.31649121076195
GO:0002020	protease binding	22/2228	136/18639	0.161764705882353	1.35329100221776	0.0860028020105215	0.329997971931746
GO:0044325	transmembrane transporter binding	22/2228	136/18639	0.161764705882353	1.35329100221776	0.0860028020105215	0.329997971931746
GO:0016776	phosphotransferase activity, phosphate group as acceptor	8/2228	39/18639	0.205128205128205	1.71606131749758	0.0867913711877672	0.331963174511173
GO:0031593	polyubiquitin modification-dependent protein binding	11/2228	59/18639	0.186440677966102	1.55972522289505	0.0882710459944661	0.335485842529601
GO:0036002	pre-mRNA binding	11/2228	59/18639	0.186440677966102	1.55972522289505	0.0882710459944661	0.335485842529601
GO:0140416	transcription regulator inhibitor activity	7/2228	33/18639	0.212121212121212	1.77456340786682	0.0913218756814871	0.345986033733331
GO:0004559	alpha-mannosidase activity	4/2228	15/18639	0.266666666666667	2.23087971274686	0.0947095770237119	0.350137600194449
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/2228	15/18639	0.266666666666667	2.23087971274686	0.0947095770237119	0.350137600194449
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/2228	15/18639	0.266666666666667	2.23087971274686	0.0947095770237119	0.350137600194449
GO:0004953	icosanoid receptor activity	4/2228	15/18639	0.266666666666667	2.23087971274686	0.0947095770237119	0.350137600194449
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	4/2228	15/18639	0.266666666666667	2.23087971274686	0.0947095770237119	0.350137600194449
GO:0141050	histone H3K deacetylase activity	4/2228	15/18639	0.266666666666667	2.23087971274686	0.0947095770237119	0.350137600194449
GO:0141051	histone H4K deacetylase activity	4/2228	15/18639	0.266666666666667	2.23087971274686	0.0947095770237119	0.350137600194449
GO:0140296	general transcription initiation factor binding	10/2228	53/18639	0.188679245283019	1.57845262694353	0.0948753114310111	0.350137600194449
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	6/2228	27/18639	0.222222222222222	1.85906642728905	0.0950415134582768	0.350137600194449
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	5/2228	21/18639	0.238095238095238	1.99185688638112	0.0969288213193041	0.35232380850854
GO:0008373	sialyltransferase activity	5/2228	21/18639	0.238095238095238	1.99185688638112	0.0969288213193041	0.35232380850854
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5/2228	21/18639	0.238095238095238	1.99185688638112	0.0969288213193041	0.35232380850854
GO:0015036	disulfide oxidoreductase activity	8/2228	40/18639	0.2	1.67315978456014	0.0976884498196034	0.35232380850854
GO:0030331	nuclear estrogen receptor binding	8/2228	40/18639	0.2	1.67315978456014	0.0976884498196034	0.35232380850854
GO:0032451	demethylase activity	8/2228	40/18639	0.2	1.67315978456014	0.0976884498196034	0.35232380850854
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	8/2228	40/18639	0.2	1.67315978456014	0.0976884498196034	0.35232380850854
GO:0035064	methylated histone binding	13/2228	74/18639	0.175675675675676	1.46966737832986	0.0988978756801547	0.355617810454688
GO:0043495	protein-membrane adaptor activity	9/2228	47/18639	0.191489361702128	1.60196149585546	0.101906509010342	0.365342439765434
GO:0015035	protein-disulfide reductase activity	7/2228	34/18639	0.205882352941176	1.72237036645897	0.103731036154428	0.368323317042808
GO:0051287	NAD binding	10/2228	54/18639	0.185185185185185	1.54922202274087	0.104611045535277	0.368323317042808
GO:0140463	chromatin-protein adaptor activity	10/2228	54/18639	0.185185185185185	1.54922202274087	0.104611045535277	0.368323317042808
GO:0001094	TFIID-class transcription factor complex binding	3/2228	10/18639	0.3	2.50973967684022	0.107644866179871	0.368323317042808
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	3/2228	10/18639	0.3	2.50973967684022	0.107644866179871	0.368323317042808
GO:0008641	ubiquitin-like modifier activating enzyme activity	3/2228	10/18639	0.3	2.50973967684022	0.107644866179871	0.368323317042808
GO:0015658	branched-chain amino acid transmembrane transporter activity	3/2228	10/18639	0.3	2.50973967684022	0.107644866179871	0.368323317042808
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/2228	10/18639	0.3	2.50973967684022	0.107644866179871	0.368323317042808
GO:0016427	tRNA (cytidine) methyltransferase activity	3/2228	10/18639	0.3	2.50973967684022	0.107644866179871	0.368323317042808
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	3/2228	10/18639	0.3	2.50973967684022	0.107644866179871	0.368323317042808
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	3/2228	10/18639	0.3	2.50973967684022	0.107644866179871	0.368323317042808
GO:0043422	protein kinase B binding	3/2228	10/18639	0.3	2.50973967684022	0.107644866179871	0.368323317042808
GO:0045322	unmethylated CpG binding	3/2228	10/18639	0.3	2.50973967684022	0.107644866179871	0.368323317042808
GO:0051864	histone H3K36 demethylase activity	3/2228	10/18639	0.3	2.50973967684022	0.107644866179871	0.368323317042808
GO:0099122	RNA polymerase II C-terminal domain binding	3/2228	10/18639	0.3	2.50973967684022	0.107644866179871	0.368323317042808
GO:1905394	retromer complex binding	3/2228	10/18639	0.3	2.50973967684022	0.107644866179871	0.368323317042808
GO:0140097	catalytic activity, acting on DNA	48/2228	336/18639	0.142857142857143	1.19511413182867	0.108382082300258	0.369792275121051
GO:0008017	microtubule binding	40/2228	276/18639	0.144927536231884	1.21243462649286	0.113641742238479	0.381088138211004
GO:0050321	tau-protein kinase activity	5/2228	22/18639	0.227272727272727	1.90131793700016	0.113696467046765	0.381088138211004
GO:0140517	protein-RNA adaptor activity	5/2228	22/18639	0.227272727272727	1.90131793700016	0.113696467046765	0.381088138211004
GO:0019210	kinase inhibitor activity	15/2228	90/18639	0.166666666666667	1.39429982046679	0.114247775794554	0.381088138211004
GO:0005521	lamin binding	4/2228	16/18639	0.25	2.09144973070018	0.114865866804649	0.381088138211004
GO:0008142	oxysterol binding	4/2228	16/18639	0.25	2.09144973070018	0.114865866804649	0.381088138211004
GO:0015923	mannosidase activity	4/2228	16/18639	0.25	2.09144973070018	0.114865866804649	0.381088138211004
GO:0022858	alanine transmembrane transporter activity	4/2228	16/18639	0.25	2.09144973070018	0.114865866804649	0.381088138211004
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/2228	16/18639	0.25	2.09144973070018	0.114865866804649	0.381088138211004
GO:0043023	ribosomal large subunit binding	4/2228	16/18639	0.25	2.09144973070018	0.114865866804649	0.381088138211004
GO:0005154	epidermal growth factor receptor binding	7/2228	35/18639	0.2	1.67315978456014	0.117000505376247	0.38603738174965
GO:0043015	gamma-tubulin binding	7/2228	35/18639	0.2	1.67315978456014	0.117000505376247	0.38603738174965
GO:0016859	cis-trans isomerase activity	8/2228	42/18639	0.19047619047619	1.5934855091049	0.121672898158067	0.400353837500927
GO:0000149	SNARE binding	17/2228	106/18639	0.160377358490566	1.341684732902	0.126870668628404	0.416316046510144
GO:0005484	SNAP receptor activity	7/2228	36/18639	0.194444444444444	1.62668312387792	0.131103479151144	0.429033456295705
GO:0140103	catalytic activity, acting on a glycoprotein	5/2228	23/18639	0.217391304347826	1.81865193973929	0.131743154510529	0.429816560374383
GO:0008200	ion channel inhibitor activity	8/2228	43/18639	0.186046511627907	1.55642770656758	0.134726374660612	0.429816560374383
GO:0008526	phosphatidylinositol transfer activity	3/2228	11/18639	0.272727272727273	2.2815815244002	0.135400133401037	0.429816560374383
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	3/2228	11/18639	0.272727272727273	2.2815815244002	0.135400133401037	0.429816560374383
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	3/2228	11/18639	0.272727272727273	2.2815815244002	0.135400133401037	0.429816560374383
GO:0019107	myristoyltransferase activity	3/2228	11/18639	0.272727272727273	2.2815815244002	0.135400133401037	0.429816560374383
GO:0032404	mismatch repair complex binding	3/2228	11/18639	0.272727272727273	2.2815815244002	0.135400133401037	0.429816560374383
GO:0070697	activin receptor binding	3/2228	11/18639	0.272727272727273	2.2815815244002	0.135400133401037	0.429816560374383
GO:0140031	phosphorylation-dependent protein binding	3/2228	11/18639	0.272727272727273	2.2815815244002	0.135400133401037	0.429816560374383
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/2228	11/18639	0.272727272727273	2.2815815244002	0.135400133401037	0.429816560374383
GO:0004549	tRNA-specific ribonuclease activity	4/2228	17/18639	0.235294117647059	1.96842327595311	0.13671101254206	0.429816560374383
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	4/2228	17/18639	0.235294117647059	1.96842327595311	0.13671101254206	0.429816560374383
GO:0031489	myosin V binding	4/2228	17/18639	0.235294117647059	1.96842327595311	0.13671101254206	0.429816560374383
GO:0046965	nuclear retinoid X receptor binding	4/2228	17/18639	0.235294117647059	1.96842327595311	0.13671101254206	0.429816560374383
GO:0048038	quinone binding	4/2228	17/18639	0.235294117647059	1.96842327595311	0.13671101254206	0.429816560374383
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	19/2228	122/18639	0.155737704918033	1.30287032404273	0.137367672712804	0.430753459342238
GO:0031210	phosphatidylcholine binding	6/2228	30/18639	0.2	1.67315978456014	0.140994404885532	0.440974688196678
GO:0019213	deacetylase activity	7/2228	37/18639	0.189189189189189	1.58271871512446	0.146006553905561	0.455464600624881
GO:0016248	channel inhibitor activity	8/2228	44/18639	0.181818181818182	1.52105434960013	0.148456687693647	0.460714423566074
GO:0016790	thiolester hydrolase activity	8/2228	44/18639	0.181818181818182	1.52105434960013	0.148456687693647	0.460714423566074
GO:0035035	histone acetyltransferase binding	5/2228	24/18639	0.208333333333333	1.74287477558348	0.150980440474641	0.467338940747534
GO:0030295	protein kinase activator activity	21/2228	139/18639	0.151079136690647	1.26389767898428	0.153886504552759	0.475109747989366
GO:0005164	tumor necrosis factor receptor binding	6/2228	31/18639	0.193548387096774	1.61918688828401	0.158235735192431	0.478820863978253
GO:0004706	JUN kinase kinase kinase activity	4/2228	18/18639	0.222222222222222	1.85906642728905	0.160069267358311	0.478820863978253
GO:0050811	GABA receptor binding	4/2228	18/18639	0.222222222222222	1.85906642728905	0.160069267358311	0.478820863978253
GO:1990381	ubiquitin-specific protease binding	4/2228	18/18639	0.222222222222222	1.85906642728905	0.160069267358311	0.478820863978253
GO:0042605	peptide antigen binding	8/2228	45/18639	0.177777777777778	1.48725314183124	0.162835284875834	0.478820863978253
GO:0141110	transporter inhibitor activity	8/2228	45/18639	0.177777777777778	1.48725314183124	0.162835284875834	0.478820863978253
GO:0000340	RNA 7-methylguanosine cap binding	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0005095	GTPase inhibitor activity	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0008179	adenylate cyclase binding	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0010853	cyclase activator activity	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0016801	hydrolase activity, acting on ether bonds	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0016803	ether hydrolase activity	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0035014	phosphatidylinositol 3-kinase regulator activity	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0035259	nuclear glucocorticoid receptor binding	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0070008	serine-type exopeptidase activity	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0097371	MDM2/MDM4 family protein binding	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0097677	STAT family protein binding	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0141221	histone deacetylase activity, hydrolytic mechanism	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:1990247	N6-methyladenosine-containing RNA reader activity	3/2228	12/18639	0.25	2.09144973070018	0.165271331660029	0.478820863978253
GO:0030971	receptor tyrosine kinase binding	13/2228	81/18639	0.160493827160494	1.34265908637542	0.165454336845108	0.478820863978253
GO:0003684	damaged DNA binding	12/2228	74/18639	0.162162162162162	1.35661604153525	0.168628501702693	0.486833727271478
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	5/2228	25/18639	0.2	1.67315978456014	0.171308407696153	0.49338464662609
GO:0031369	translation initiation factor binding	6/2228	32/18639	0.1875	1.56858729802513	0.176337977384941	0.504478079811673
GO:0043425	bHLH transcription factor binding	6/2228	32/18639	0.1875	1.56858729802513	0.176337977384941	0.504478079811673
GO:0005246	calcium channel regulator activity	9/2228	53/18639	0.169811320754717	1.42060736424918	0.176420311008245	0.504478079811673
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	7/2228	39/18639	0.179487179487179	1.50155365281039	0.178050111643487	0.507929178346385
GO:0005548	phospholipid transporter activity	11/2228	68/18639	0.161764705882353	1.35329100221776	0.184062324926024	0.523317111949994
GO:0031420	alkali metal ion binding	4/2228	19/18639	0.210526315789474	1.76122082585278	0.184751420038965	0.523317111949994
GO:0046624	sphingolipid transporter activity	4/2228	19/18639	0.210526315789474	1.76122082585278	0.184751420038965	0.523317111949994
GO:0016757	glycosyltransferase activity	37/2228	267/18639	0.138576779026217	1.15930546870272	0.190212466924069	0.537518053590134
GO:0004112	cyclic-nucleotide phosphodiesterase activity	5/2228	26/18639	0.192307692307692	1.60880748515398	0.192618258367167	0.538493991429692
GO:0005112	Notch binding	5/2228	26/18639	0.192307692307692	1.60880748515398	0.192618258367167	0.538493991429692
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/2228	26/18639	0.192307692307692	1.60880748515398	0.192618258367167	0.538493991429692
GO:0034237	protein kinase A regulatory subunit binding	5/2228	26/18639	0.192307692307692	1.60880748515398	0.192618258367167	0.538493991429692
GO:0140359	ABC-type transporter activity	8/2228	47/18639	0.170212765957447	1.42396577409374	0.193403598997194	0.538493991429692
GO:0050997	quaternary ammonium group binding	7/2228	40/18639	0.175	1.46401481149013	0.195096524757644	0.538493991429692
GO:0140662	ATP-dependent protein folding chaperone	7/2228	40/18639	0.175	1.46401481149013	0.195096524757644	0.538493991429692
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	24/2228	167/18639	0.143712574850299	1.20227050387555	0.195824916069882	0.538493991429692
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/2228	13/18639	0.230769230769231	1.93056898218478	0.19683502267913	0.538493991429692
GO:0005338	nucleotide-sugar transmembrane transporter activity	3/2228	13/18639	0.230769230769231	1.93056898218478	0.19683502267913	0.538493991429692
GO:0019855	calcium channel inhibitor activity	3/2228	13/18639	0.230769230769231	1.93056898218478	0.19683502267913	0.538493991429692
GO:0030955	potassium ion binding	3/2228	13/18639	0.230769230769231	1.93056898218478	0.19683502267913	0.538493991429692
GO:0046975	histone H3K36 methyltransferase activity	3/2228	13/18639	0.230769230769231	1.93056898218478	0.19683502267913	0.538493991429692
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	3/2228	13/18639	0.230769230769231	1.93056898218478	0.19683502267913	0.538493991429692
GO:0016247	channel regulator activity	24/2228	168/18639	0.142857142857143	1.19511413182867	0.204129598599822	0.557181017996332
GO:0000339	RNA cap binding	4/2228	20/18639	0.2	1.67315978456014	0.210560640405803	0.569557047584166
GO:0010851	cyclase regulator activity	4/2228	20/18639	0.2	1.67315978456014	0.210560640405803	0.569557047584166
GO:0015095	magnesium ion transmembrane transporter activity	4/2228	20/18639	0.2	1.67315978456014	0.210560640405803	0.569557047584166
GO:0016505	peptidase activator activity involved in apoptotic process	4/2228	20/18639	0.2	1.67315978456014	0.210560640405803	0.569557047584166
GO:0042287	MHC protein binding	7/2228	41/18639	0.170731707317073	1.4283071331611	0.212756307477377	0.574202978158044
GO:0001671	ATPase activator activity	5/2228	27/18639	0.185185185185185	1.54922202274087	0.214794791301005	0.577225481090768
GO:0016831	carboxy-lyase activity	6/2228	34/18639	0.176470588235294	1.47631745696483	0.214837460489237	0.577225481090768
GO:0141108	transporter regulator activity	24/2228	170/18639	0.141176470588235	1.18105396557187	0.221241776463789	0.593105744493327
GO:0004518	nuclease activity	29/2228	209/18639	0.138755980861244	1.16080463522115	0.221883669655645	0.593501753355076
GO:0008174	mRNA methyltransferase activity	3/2228	14/18639	0.214285714285714	1.79267119774301	0.229681528800854	0.598367713860792
GO:0008474	palmitoyl-(protein) hydrolase activity	3/2228	14/18639	0.214285714285714	1.79267119774301	0.229681528800854	0.598367713860792
GO:0008494	translation activator activity	3/2228	14/18639	0.214285714285714	1.79267119774301	0.229681528800854	0.598367713860792
GO:0015926	glucosidase activity	3/2228	14/18639	0.214285714285714	1.79267119774301	0.229681528800854	0.598367713860792
GO:0030983	mismatched DNA binding	3/2228	14/18639	0.214285714285714	1.79267119774301	0.229681528800854	0.598367713860792
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	3/2228	14/18639	0.214285714285714	1.79267119774301	0.229681528800854	0.598367713860792
GO:0042043	neurexin family protein binding	3/2228	14/18639	0.214285714285714	1.79267119774301	0.229681528800854	0.598367713860792
GO:0046030	inositol trisphosphate phosphatase activity	3/2228	14/18639	0.214285714285714	1.79267119774301	0.229681528800854	0.598367713860792
GO:0061665	SUMO ligase activity	3/2228	14/18639	0.214285714285714	1.79267119774301	0.229681528800854	0.598367713860792
GO:0071933	Arp2/3 complex binding	3/2228	14/18639	0.214285714285714	1.79267119774301	0.229681528800854	0.598367713860792
GO:0098599	palmitoyl hydrolase activity	3/2228	14/18639	0.214285714285714	1.79267119774301	0.229681528800854	0.598367713860792
GO:1990825	sequence-specific mRNA binding	3/2228	14/18639	0.214285714285714	1.79267119774301	0.229681528800854	0.598367713860792
GO:1990782	protein tyrosine kinase binding	17/2228	117/18639	0.145299145299145	1.21554343322745	0.230752306869273	0.599132959392717
GO:0019894	kinesin binding	7/2228	42/18639	0.166666666666667	1.39429982046679	0.230972989341239	0.599132959392717
GO:0008081	phosphoric diester hydrolase activity	13/2228	87/18639	0.149425287356322	1.25006190800471	0.236523140726309	0.607447189224421
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	4/2228	21/18639	0.19047619047619	1.5934855091049	0.237297539014391	0.607447189224421
GO:0051010	microtubule plus-end binding	4/2228	21/18639	0.19047619047619	1.5934855091049	0.237297539014391	0.607447189224421
GO:0072542	protein phosphatase activator activity	4/2228	21/18639	0.19047619047619	1.5934855091049	0.237297539014391	0.607447189224421
GO:0140312	cargo adaptor activity	4/2228	21/18639	0.19047619047619	1.5934855091049	0.237297539014391	0.607447189224421
GO:0019789	SUMO transferase activity	5/2228	28/18639	0.178571428571429	1.49389266478584	0.237718716848857	0.607447189224421
GO:0097718	disordered domain specific binding	5/2228	28/18639	0.178571428571429	1.49389266478584	0.237718716848857	0.607447189224421
GO:0032813	tumor necrosis factor receptor superfamily binding	8/2228	50/18639	0.16	1.33852782764811	0.243197813566232	0.62012860741623
GO:0004712	protein serine/threonine/tyrosine kinase activity	7/2228	43/18639	0.162790697674419	1.36187424324663	0.249687608862472	0.633984816583148
GO:0008375	acetylglucosaminyltransferase activity	7/2228	43/18639	0.162790697674419	1.36187424324663	0.249687608862472	0.633984816583148
GO:0055106	ubiquitin-protein transferase regulator activity	6/2228	36/18639	0.166666666666667	1.39429982046679	0.255874811129736	0.642388074988282
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	6/2228	36/18639	0.166666666666667	1.39429982046679	0.255874811129736	0.642388074988282
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	6/2228	36/18639	0.166666666666667	1.39429982046679	0.255874811129736	0.642388074988282
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	6/2228	36/18639	0.166666666666667	1.39429982046679	0.255874811129736	0.642388074988282
GO:0001618	virus receptor activity	12/2228	81/18639	0.148148148148148	1.2393776181927	0.257750214035984	0.642388074988282
GO:0016830	carbon-carbon lyase activity	8/2228	51/18639	0.156862745098039	1.31228218396874	0.260673188018191	0.642388074988282
GO:0004629	phospholipase C activity	5/2228	29/18639	0.172413793103448	1.44237912462081	0.261268777235613	0.642388074988282
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	5/2228	29/18639	0.172413793103448	1.44237912462081	0.261268777235613	0.642388074988282
GO:0016417	S-acyltransferase activity	5/2228	29/18639	0.172413793103448	1.44237912462081	0.261268777235613	0.642388074988282
GO:0097472	cyclin-dependent protein kinase activity	5/2228	29/18639	0.172413793103448	1.44237912462081	0.261268777235613	0.642388074988282
GO:0017081	chloride channel regulator activity	3/2228	15/18639	0.2	1.67315978456014	0.263424516745139	0.642388074988282
GO:0031386	protein tag activity	3/2228	15/18639	0.2	1.67315978456014	0.263424516745139	0.642388074988282
GO:0034483	heparan sulfate sulfotransferase activity	3/2228	15/18639	0.2	1.67315978456014	0.263424516745139	0.642388074988282
GO:0050700	CARD domain binding	3/2228	15/18639	0.2	1.67315978456014	0.263424516745139	0.642388074988282
GO:0055105	ubiquitin-protein transferase inhibitor activity	3/2228	15/18639	0.2	1.67315978456014	0.263424516745139	0.642388074988282
GO:0120283	protein serine/threonine kinase binding	3/2228	15/18639	0.2	1.67315978456014	0.263424516745139	0.642388074988282
GO:0141047	molecular tag activity	3/2228	15/18639	0.2	1.67315978456014	0.263424516745139	0.642388074988282
GO:0008649	rRNA methyltransferase activity	4/2228	22/18639	0.181818181818182	1.52105434960013	0.264764443896086	0.642388074988282
GO:0034062	5'-3' RNA polymerase activity	4/2228	22/18639	0.181818181818182	1.52105434960013	0.264764443896086	0.642388074988282
GO:0061133	endopeptidase activator activity	4/2228	22/18639	0.181818181818182	1.52105434960013	0.264764443896086	0.642388074988282
GO:0070034	telomerase RNA binding	4/2228	22/18639	0.181818181818182	1.52105434960013	0.264764443896086	0.642388074988282
GO:0097747	RNA polymerase activity	4/2228	22/18639	0.181818181818182	1.52105434960013	0.264764443896086	0.642388074988282
GO:0043014	alpha-tubulin binding	7/2228	44/18639	0.159090909090909	1.33092255590011	0.268839404759277	0.649196310026347
GO:0004879	nuclear receptor activity	9/2228	59/18639	0.152542372881356	1.27613881873231	0.269192141876037	0.649196310026347
GO:0070888	E-box binding	9/2228	59/18639	0.152542372881356	1.27613881873231	0.269192141876037	0.649196310026347
GO:0140272	exogenous protein binding	12/2228	82/18639	0.146341463414634	1.22426325699523	0.271683050626011	0.653890468540759
GO:0099106	ion channel regulator activity	22/2228	160/18639	0.1375	1.1502973518851	0.273840287909754	0.656587719063386
GO:0005096	GTPase activator activity	36/2228	271/18639	0.132841328413284	1.11132384214327	0.27389712510471	0.656587719063386
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	9/2228	60/18639	0.15	1.25486983842011	0.285945774295571	0.682745278188828
GO:0098531	ligand-modulated transcription factor activity	9/2228	60/18639	0.15	1.25486983842011	0.285945774295571	0.682745278188828
GO:0015078	proton transmembrane transporter activity	25/2228	185/18639	0.135135135135135	1.13051336794604	0.286622009810071	0.683002051154555
GO:0005158	insulin receptor binding	4/2228	23/18639	0.173913043478261	1.45492155179143	0.292768925871993	0.690796620770656
GO:0008171	O-methyltransferase activity	4/2228	23/18639	0.173913043478261	1.45492155179143	0.292768925871993	0.690796620770656
GO:0043274	phospholipase binding	4/2228	23/18639	0.173913043478261	1.45492155179143	0.292768925871993	0.690796620770656
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/2228	23/18639	0.173913043478261	1.45492155179143	0.292768925871993	0.690796620770656
GO:0140102	catalytic activity, acting on a rRNA	4/2228	23/18639	0.173913043478261	1.45492155179143	0.292768925871993	0.690796620770656
GO:0016251	RNA polymerase II general transcription initiation factor activity	8/2228	53/18639	0.150943396226415	1.26276210155483	0.296658780204695	0.692919468646011
GO:0003688	DNA replication origin binding	3/2228	16/18639	0.1875	1.56858729802513	0.297707282116021	0.692919468646011
GO:0005159	insulin-like growth factor receptor binding	3/2228	16/18639	0.1875	1.56858729802513	0.297707282116021	0.692919468646011
GO:0008296	3'-5'-DNA exonuclease activity	3/2228	16/18639	0.1875	1.56858729802513	0.297707282116021	0.692919468646011
GO:0015562	efflux transmembrane transporter activity	3/2228	16/18639	0.1875	1.56858729802513	0.297707282116021	0.692919468646011
GO:0017070	U6 snRNA binding	3/2228	16/18639	0.1875	1.56858729802513	0.297707282116021	0.692919468646011
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	3/2228	16/18639	0.1875	1.56858729802513	0.297707282116021	0.692919468646011
GO:0042162	telomeric DNA binding	6/2228	38/18639	0.157894736842105	1.32091561938959	0.298790128369809	0.694094669578609
GO:0016836	hydro-lyase activity	9/2228	61/18639	0.147540983606557	1.2342982017247	0.302968059157112	0.701087936508075
GO:0019905	syntaxin binding	9/2228	61/18639	0.147540983606557	1.2342982017247	0.302968059157112	0.701087936508075
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	8/2228	54/18639	0.148148148148148	1.2393776181927	0.315072104744148	0.727129595210618
GO:0016853	isomerase activity	24/2228	180/18639	0.133333333333333	1.11543985637343	0.315432572110518	0.727129595210618
GO:0001091	RNA polymerase II general transcription initiation factor binding	4/2228	24/18639	0.166666666666667	1.39429982046679	0.321126622951464	0.736017317108221
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/2228	24/18639	0.166666666666667	1.39429982046679	0.321126622951464	0.736017317108221
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/2228	24/18639	0.166666666666667	1.39429982046679	0.321126622951464	0.736017317108221
GO:0140938	histone H3 methyltransferase activity	7/2228	47/18639	0.148936170212766	1.24597005233202	0.328296922478937	0.74226993756478
GO:0004550	nucleoside diphosphate kinase activity	3/2228	17/18639	0.176470588235294	1.47631745696483	0.332206482739012	0.74226993756478
GO:0004659	prenyltransferase activity	3/2228	17/18639	0.176470588235294	1.47631745696483	0.332206482739012	0.74226993756478
GO:0008429	phosphatidylethanolamine binding	3/2228	17/18639	0.176470588235294	1.47631745696483	0.332206482739012	0.74226993756478
GO:0032977	membrane insertase activity	3/2228	17/18639	0.176470588235294	1.47631745696483	0.332206482739012	0.74226993756478
GO:0045125	bioactive lipid receptor activity	3/2228	17/18639	0.176470588235294	1.47631745696483	0.332206482739012	0.74226993756478
GO:1990226	histone methyltransferase binding	3/2228	17/18639	0.176470588235294	1.47631745696483	0.332206482739012	0.74226993756478
GO:0004382	GDP phosphatase activity	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0004955	prostaglandin receptor activity	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0008239	dipeptidyl-peptidase activity	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0015643	toxic substance binding	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0030957	Tat protein binding	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0031434	mitogen-activated protein kinase kinase binding	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0033204	ribonuclease P RNA binding	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0050308	sugar-phosphatase activity	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0070097	delta-catenin binding	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0140999	histone H3K4 trimethyltransferase activity	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/2228	10/18639	0.2	1.67315978456014	0.339923784896444	0.74226993756478
GO:0004177	aminopeptidase activity	6/2228	40/18639	0.15	1.25486983842011	0.342915741141223	0.746090226649653
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	6/2228	40/18639	0.15	1.25486983842011	0.342915741141223	0.746090226649653
GO:0016879	ligase activity, forming carbon-nitrogen bonds	7/2228	48/18639	0.145833333333333	1.22001234290844	0.348576258714607	0.753942144442625
GO:0015662	P-type ion transporter activity	4/2228	25/18639	0.16	1.33852782764811	0.349663425857237	0.753942144442625
GO:0017025	TBP-class protein binding	4/2228	25/18639	0.16	1.33852782764811	0.349663425857237	0.753942144442625
GO:0019211	phosphatase activator activity	4/2228	25/18639	0.16	1.33852782764811	0.349663425857237	0.753942144442625
GO:0140358	P-type transmembrane transporter activity	4/2228	25/18639	0.16	1.33852782764811	0.349663425857237	0.753942144442625
GO:0019212	phosphatase inhibitor activity	8/2228	56/18639	0.142857142857143	1.19511413182867	0.35249623595674	0.758688135096855
GO:0016829	lyase activity	26/2228	200/18639	0.13	1.08755385996409	0.354635140458206	0.761926303560475
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	5/2228	33/18639	0.151515151515152	1.26754529133344	0.359336670608883	0.770648823930836
GO:0015175	neutral L-amino acid transmembrane transporter activity	6/2228	41/18639	0.146341463414634	1.22426325699523	0.365228786912168	0.771151216994743
GO:0016877	ligase activity, forming carbon-sulfur bonds	6/2228	41/18639	0.146341463414634	1.22426325699523	0.365228786912168	0.771151216994743
GO:0000400	four-way junction DNA binding	3/2228	18/18639	0.166666666666667	1.39429982046679	0.366633925815153	0.771151216994743
GO:0000900	mRNA regulatory element binding translation repressor activity	3/2228	18/18639	0.166666666666667	1.39429982046679	0.366633925815153	0.771151216994743
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	3/2228	18/18639	0.166666666666667	1.39429982046679	0.366633925815153	0.771151216994743
GO:0008525	phosphatidylcholine transporter activity	3/2228	18/18639	0.166666666666667	1.39429982046679	0.366633925815153	0.771151216994743
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/2228	18/18639	0.166666666666667	1.39429982046679	0.366633925815153	0.771151216994743
GO:0017128	phospholipid scramblase activity	3/2228	18/18639	0.166666666666667	1.39429982046679	0.366633925815153	0.771151216994743
GO:0031690	adrenergic receptor binding	3/2228	18/18639	0.166666666666667	1.39429982046679	0.366633925815153	0.771151216994743
GO:0035615	clathrin adaptor activity	3/2228	18/18639	0.166666666666667	1.39429982046679	0.366633925815153	0.771151216994743
GO:0070628	proteasome binding	3/2228	18/18639	0.166666666666667	1.39429982046679	0.366633925815153	0.771151216994743
GO:0015932	nucleobase-containing compound transmembrane transporter activity	8/2228	57/18639	0.140350877192982	1.17414721723519	0.371410625560004	0.779832449820918
GO:0120013	lipid transfer activity	9/2228	65/18639	0.138461538461538	1.15834138931087	0.372956147071477	0.781710877195191
GO:0051139	metal cation:proton antiporter activity	4/2228	26/18639	0.153846153846154	1.28704598812319	0.378217092673613	0.783136304161991
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	5/2228	34/18639	0.147058823529412	1.23026454747069	0.384250327526063	0.783136304161991
GO:0030332	cyclin binding	5/2228	34/18639	0.147058823529412	1.23026454747069	0.384250327526063	0.783136304161991
GO:0004143	ATP-dependent diacylglycerol kinase activity	2/2228	11/18639	0.181818181818182	1.52105434960013	0.385373485228757	0.783136304161991
GO:0004954	prostanoid receptor activity	2/2228	11/18639	0.181818181818182	1.52105434960013	0.385373485228757	0.783136304161991
GO:0005225	volume-sensitive anion channel activity	2/2228	11/18639	0.181818181818182	1.52105434960013	0.385373485228757	0.783136304161991
GO:0005536	D-glucose binding	2/2228	11/18639	0.181818181818182	1.52105434960013	0.385373485228757	0.783136304161991
GO:0008432	JUN kinase binding	2/2228	11/18639	0.181818181818182	1.52105434960013	0.385373485228757	0.783136304161991
GO:0015173	aromatic amino acid transmembrane transporter activity	2/2228	11/18639	0.181818181818182	1.52105434960013	0.385373485228757	0.783136304161991
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/2228	11/18639	0.181818181818182	1.52105434960013	0.385373485228757	0.783136304161991
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/2228	11/18639	0.181818181818182	1.52105434960013	0.385373485228757	0.783136304161991
GO:0019203	carbohydrate phosphatase activity	2/2228	11/18639	0.181818181818182	1.52105434960013	0.385373485228757	0.783136304161991
GO:0019215	intermediate filament binding	2/2228	11/18639	0.181818181818182	1.52105434960013	0.385373485228757	0.783136304161991
GO:0032050	clathrin heavy chain binding	2/2228	11/18639	0.181818181818182	1.52105434960013	0.385373485228757	0.783136304161991
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/2228	11/18639	0.181818181818182	1.52105434960013	0.385373485228757	0.783136304161991
GO:0034511	U3 snoRNA binding	2/2228	11/18639	0.181818181818182	1.52105434960013	0.385373485228757	0.783136304161991
GO:0180030	inositol phosphate kinase activity	2/2228	11/18639	0.181818181818182	1.52105434960013	0.385373485228757	0.783136304161991
GO:1990948	ubiquitin ligase inhibitor activity	2/2228	11/18639	0.181818181818182	1.52105434960013	0.385373485228757	0.783136304161991
GO:0022804	active transmembrane transporter activity	57/2228	457/18639	0.12472647702407	1.04343662713269	0.386048960212902	0.783183785837323
GO:0008170	N-methyltransferase activity	13/2228	98/18639	0.13265306122449	1.10974883669805	0.388976983285889	0.786466930852446
GO:0042626	ATPase-coupled transmembrane transporter activity	13/2228	98/18639	0.13265306122449	1.10974883669805	0.388976983285889	0.786466930852446
GO:0008168	methyltransferase activity	26/2228	204/18639	0.127450980392157	1.0662292744746	0.39465769223528	0.79661157710012
GO:0042800	histone H3K4 methyltransferase activity	3/2228	19/18639	0.157894736842105	1.32091561938959	0.400736895648188	0.804824434236578
GO:0050145	nucleoside monophosphate kinase activity	3/2228	19/18639	0.157894736842105	1.32091561938959	0.400736895648188	0.804824434236578
GO:0070003	threonine-type peptidase activity	3/2228	19/18639	0.157894736842105	1.32091561938959	0.400736895648188	0.804824434236578
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	60/2228	484/18639	0.12396694214876	1.037082511091	0.401421700441442	0.804853860150537
GO:0046982	protein heterodimerization activity	46/2228	369/18639	0.124661246612466	1.04289092262556	0.403516800674348	0.80770612934982
GO:0004683	calcium/calmodulin-dependent protein kinase activity	4/2228	27/18639	0.148148148148148	1.2393776181927	0.406638362477545	0.811250287932776
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/2228	27/18639	0.148148148148148	1.2393776181927	0.406638362477545	0.811250287932776
GO:0015459	potassium channel regulator activity	8/2228	59/18639	0.135593220338983	1.13434561665094	0.40940947987375	0.815188086571564
GO:0048156	tau protein binding	6/2228	43/18639	0.13953488372093	1.16732077992568	0.409969695494775	0.815188086571564
GO:0140223	general transcription initiation factor activity	9/2228	68/18639	0.132352941176471	1.10723809272362	0.426353022985769	0.833121313484566
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	8/2228	60/18639	0.133333333333333	1.11543985637343	0.428403896116546	0.833121313484566
GO:0004000	adenosine deaminase activity	2/2228	12/18639	0.166666666666667	1.39429982046679	0.429393915942503	0.833121313484566
GO:0004300	enoyl-CoA hydratase activity	2/2228	12/18639	0.166666666666667	1.39429982046679	0.429393915942503	0.833121313484566
GO:0004526	ribonuclease P activity	2/2228	12/18639	0.166666666666667	1.39429982046679	0.429393915942503	0.833121313484566
GO:0005049	nuclear export signal receptor activity	2/2228	12/18639	0.166666666666667	1.39429982046679	0.429393915942503	0.833121313484566
GO:0005247	voltage-gated chloride channel activity	2/2228	12/18639	0.166666666666667	1.39429982046679	0.429393915942503	0.833121313484566
GO:0005436	sodium:phosphate symporter activity	2/2228	12/18639	0.166666666666667	1.39429982046679	0.429393915942503	0.833121313484566
GO:0015368	calcium:monoatomic cation antiporter activity	2/2228	12/18639	0.166666666666667	1.39429982046679	0.429393915942503	0.833121313484566
GO:0016423	tRNA (guanine) methyltransferase activity	2/2228	12/18639	0.166666666666667	1.39429982046679	0.429393915942503	0.833121313484566
GO:0017166	vinculin binding	2/2228	12/18639	0.166666666666667	1.39429982046679	0.429393915942503	0.833121313484566
GO:0034452	dynactin binding	2/2228	12/18639	0.166666666666667	1.39429982046679	0.429393915942503	0.833121313484566
GO:0035251	UDP-glucosyltransferase activity	2/2228	12/18639	0.166666666666667	1.39429982046679	0.429393915942503	0.833121313484566
GO:0042301	phosphate ion binding	2/2228	12/18639	0.166666666666667	1.39429982046679	0.429393915942503	0.833121313484566
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	2/2228	12/18639	0.166666666666667	1.39429982046679	0.429393915942503	0.833121313484566
GO:0019205	nucleobase-containing compound kinase activity	6/2228	44/18639	0.136363636363636	1.1407907622001	0.432253425610906	0.836834544447982
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	3/2228	20/18639	0.15	1.25486983842011	0.434297411279197	0.836834544447982
GO:0052745	inositol phosphate phosphatase activity	3/2228	20/18639	0.15	1.25486983842011	0.434297411279197	0.836834544447982
GO:0050698	proteoglycan sulfotransferase activity	4/2228	28/18639	0.142857142857143	1.19511413182867	0.434791636748993	0.836834544447982
GO:0051019	mitogen-activated protein kinase binding	4/2228	28/18639	0.142857142857143	1.19511413182867	0.434791636748993	0.836834544447982
GO:0016874	ligase activity	21/2228	167/18639	0.125748502994012	1.05198669089111	0.437143716090042	0.840015364838625
GO:0001216	DNA-binding transcription activator activity	60/2228	491/18639	0.122199592668024	1.02229722070885	0.448004006718228	0.85950928445462
GO:0035091	phosphatidylinositol binding	35/2228	284/18639	0.123239436619718	1.03099634611981	0.450568373416513	0.863050424997181
GO:0140303	intramembrane lipid transporter activity	6/2228	45/18639	0.133333333333333	1.11543985637343	0.454389878862639	0.868984465786671
GO:0097110	scaffold protein binding	9/2228	70/18639	0.128571428571429	1.07560271864581	0.461826577075765	0.8817919181264
GO:0051861	glycolipid binding	4/2228	29/18639	0.137931034482759	1.15390329969665	0.462555294271134	0.8817919181264
GO:0008276	protein methyltransferase activity	12/2228	95/18639	0.126315789473684	1.05673249551167	0.465817991151972	0.883751167938594
GO:1904047	S-adenosyl-L-methionine binding	3/2228	21/18639	0.142857142857143	1.19511413182867	0.467130723323332	0.883751167938594
GO:0005035	death receptor activity	2/2228	13/18639	0.153846153846154	1.28704598812319	0.471677351081298	0.883751167938594
GO:0005542	folic acid binding	2/2228	13/18639	0.153846153846154	1.28704598812319	0.471677351081298	0.883751167938594
GO:0008417	fucosyltransferase activity	2/2228	13/18639	0.153846153846154	1.28704598812319	0.471677351081298	0.883751167938594
GO:0009982	pseudouridine synthase activity	2/2228	13/18639	0.153846153846154	1.28704598812319	0.471677351081298	0.883751167938594
GO:0031432	titin binding	2/2228	13/18639	0.153846153846154	1.28704598812319	0.471677351081298	0.883751167938594
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/2228	13/18639	0.153846153846154	1.28704598812319	0.471677351081298	0.883751167938594
GO:0051011	microtubule minus-end binding	2/2228	13/18639	0.153846153846154	1.28704598812319	0.471677351081298	0.883751167938594
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/2228	13/18639	0.153846153846154	1.28704598812319	0.471677351081298	0.883751167938594
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/2228	13/18639	0.153846153846154	1.28704598812319	0.471677351081298	0.883751167938594
GO:0016835	carbon-oxygen lyase activity	10/2228	79/18639	0.126582278481013	1.05896188896212	0.474501838012706	0.887658422824392
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	6/2228	46/18639	0.130434782608696	1.09119116384357	0.476317396568191	0.88828756720248
GO:0030291	protein serine/threonine kinase inhibitor activity	6/2228	46/18639	0.130434782608696	1.09119116384357	0.476317396568191	0.88828756720248
GO:0005109	frizzled binding	5/2228	38/18639	0.131578947368421	1.10076301615799	0.482480068346607	0.896994678149032
GO:0043531	ADP binding	5/2228	38/18639	0.131578947368421	1.10076301615799	0.482480068346607	0.896994678149032
GO:0016769	transferase activity, transferring nitrogenous groups	4/2228	30/18639	0.133333333333333	1.11543985637343	0.489821700819673	0.907833121426585
GO:0048019	receptor antagonist activity	4/2228	30/18639	0.133333333333333	1.11543985637343	0.489821700819673	0.907833121426585
GO:1990518	single-stranded 3'-5' DNA helicase activity	6/2228	47/18639	0.127659574468085	1.0679743305703	0.49797892936174	0.920735846090345
GO:0008093	cytoskeletal anchor activity	3/2228	22/18639	0.136363636363636	1.1407907622001	0.499083293759213	0.920735846090345
GO:0031683	G-protein beta/gamma-subunit complex binding	3/2228	22/18639	0.136363636363636	1.1407907622001	0.499083293759213	0.920735846090345
GO:0016741	transferase activity, transferring one-carbon groups	26/2228	215/18639	0.12093023255814	1.01167800926892	0.506355089150513	0.932718500107004
GO:0005545	1-phosphatidylinositol binding	2/2228	14/18639	0.142857142857143	1.19511413182867	0.512009988128038	0.937384139850265
GO:0008559	ABC-type xenobiotic transporter activity	2/2228	14/18639	0.142857142857143	1.19511413182867	0.512009988128038	0.937384139850265
GO:0032454	histone H3K9 demethylase activity	2/2228	14/18639	0.142857142857143	1.19511413182867	0.512009988128038	0.937384139850265
GO:0042813	Wnt receptor activity	2/2228	14/18639	0.142857142857143	1.19511413182867	0.512009988128038	0.937384139850265
GO:0070273	phosphatidylinositol-4-phosphate binding	4/2228	31/18639	0.129032258064516	1.07945792552267	0.516496969733629	0.942724712234176
GO:0072349	modified amino acid transmembrane transporter activity	4/2228	31/18639	0.129032258064516	1.07945792552267	0.516496969733629	0.942724712234176
GO:0043138	3'-5' DNA helicase activity	6/2228	48/18639	0.125	1.04572486535009	0.519322168025616	0.946442979967777
GO:0003887	DNA-directed DNA polymerase activity	3/2228	23/18639	0.130434782608696	1.09119116384357	0.530030448942296	0.963035656852795
GO:0070577	lysine-acetylated histone binding	3/2228	23/18639	0.130434782608696	1.09119116384357	0.530030448942296	0.963035656852795
GO:0003678	DNA helicase activity	9/2228	74/18639	0.121621621621622	1.01746203115144	0.531284646397436	0.963856284476315
GO:0001540	amyloid-beta binding	10/2228	83/18639	0.120481927710843	1.00792758106033	0.539883495942834	0.97650614251106
GO:0030165	PDZ domain binding	10/2228	83/18639	0.120481927710843	1.00792758106033	0.539883495942834	0.97650614251106
GO:0042910	xenobiotic transmembrane transporter activity	4/2228	32/18639	0.125	1.04572486535009	0.542500523854886	0.979764103984538
GO:0005041	low-density lipoprotein particle receptor activity	2/2228	15/18639	0.133333333333333	1.11543985637343	0.550253906802331	0.987825025515097
GO:0016846	carbon-sulfur lyase activity	2/2228	15/18639	0.133333333333333	1.11543985637343	0.550253906802331	0.987825025515097
GO:0047372	monoacylglycerol lipase activity	2/2228	15/18639	0.133333333333333	1.11543985637343	0.550253906802331	0.987825025515097
GO:0050780	dopamine receptor binding	2/2228	15/18639	0.133333333333333	1.11543985637343	0.550253906802331	0.987825025515097
GO:0001530	lipopolysaccharide binding	5/2228	41/18639	0.121951219512195	1.02021938082936	0.552429965741387	0.988563276936771
GO:0140828	metal cation:monoatomic cation antiporter activity	5/2228	41/18639	0.121951219512195	1.02021938082936	0.552429965741387	0.988563276936771
GO:0003730	mRNA 3'-UTR binding	31/2228	262/18639	0.118320610687023	0.989846437430619	0.553134489676528	0.988563276936771
GO:0015297	antiporter activity	16/2228	135/18639	0.118518518518519	0.991502094554159	0.554387650989179	0.989330711497778
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	8/2228	67/18639	0.119402985074627	0.998901363916504	0.557534538849716	0.990292337318087
GO:0019957	C-C chemokine binding	3/2228	24/18639	0.125	1.04572486535009	0.559873852655271	0.990292337318087
GO:0070300	phosphatidic acid binding	3/2228	24/18639	0.125	1.04572486535009	0.559873852655271	0.990292337318087
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	3/2228	24/18639	0.125	1.04572486535009	0.559873852655271	0.990292337318087
GO:0070840	dynein complex binding	3/2228	24/18639	0.125	1.04572486535009	0.559873852655271	0.990292337318087
GO:0140033	acetylation-dependent protein binding	3/2228	24/18639	0.125	1.04572486535009	0.559873852655271	0.990292337318087
GO:0015605	organophosphate ester transmembrane transporter activity	6/2228	50/18639	0.12	1.00389587073609	0.560868559025509	0.990592852043582
GO:0017022	myosin binding	9/2228	76/18639	0.118421052631579	0.99068671454219	0.564810466586177	0.996090118017619
GO:0019956	chemokine binding	4/2228	33/18639	0.121212121212121	1.01403623306675	0.567764503612954	0.999831625863868
GO:0032934	sterol binding	8/2228	68/18639	0.117647058823529	0.984211637976555	0.575025407631576	1
GO:0030544	Hsp70 protein binding	6/2228	51/18639	0.117647058823529	0.984211637976555	0.580991093313648	1
GO:0000062	fatty-acyl-CoA binding	2/2228	16/18639	0.125	1.04572486535009	0.586331996043232	1
GO:0015385	sodium:proton antiporter activity	2/2228	16/18639	0.125	1.04572486535009	0.586331996043232	1
GO:0097027	ubiquitin-protein transferase activator activity	2/2228	16/18639	0.125	1.04572486535009	0.586331996043232	1
GO:0140328	floppase activity	2/2228	16/18639	0.125	1.04572486535009	0.586331996043232	1
GO:0008483	transaminase activity	3/2228	25/18639	0.12	1.00389587073609	0.588538910855004	1
GO:0015645	fatty acid ligase activity	3/2228	25/18639	0.12	1.00389587073609	0.588538910855004	1
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	3/2228	25/18639	0.12	1.00389587073609	0.588538910855004	1
GO:0019706	protein-cysteine S-palmitoyltransferase activity	3/2228	25/18639	0.12	1.00389587073609	0.588538910855004	1
GO:0019707	protein-cysteine S-acyltransferase activity	3/2228	25/18639	0.12	1.00389587073609	0.588538910855004	1
GO:0120515	fatty acid-CoA ligase activity	3/2228	25/18639	0.12	1.00389587073609	0.588538910855004	1
GO:0016279	protein-lysine N-methyltransferase activity	8/2228	69/18639	0.115942028985507	0.969947701194286	0.592192608468019	1
GO:0008175	tRNA methyltransferase activity	4/2228	34/18639	0.117647058823529	0.984211637976555	0.59223306042454	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	4/2228	34/18639	0.117647058823529	0.984211637976555	0.59223306042454	1
GO:0016278	lysine N-methyltransferase activity	8/2228	70/18639	0.114285714285714	0.956091305462939	0.609014031873471	1
GO:0004623	phospholipase A2 activity	4/2228	35/18639	0.114285714285714	0.956091305462939	0.615861569220199	1
GO:0034061	DNA polymerase activity	4/2228	35/18639	0.114285714285714	0.956091305462939	0.615861569220199	1
GO:0004435	phosphatidylinositol phospholipase C activity	3/2228	26/18639	0.115384615384615	0.965284491092391	0.615972191487358	1
GO:0004529	DNA exonuclease activity	3/2228	26/18639	0.115384615384615	0.965284491092391	0.615972191487358	1
GO:0008198	ferrous iron binding	3/2228	26/18639	0.115384615384615	0.965284491092391	0.615972191487358	1
GO:0030507	spectrin binding	3/2228	26/18639	0.115384615384615	0.965284491092391	0.615972191487358	1
GO:0070006	metalloaminopeptidase activity	3/2228	26/18639	0.115384615384615	0.965284491092391	0.615972191487358	1
GO:0030547	signaling receptor inhibitor activity	5/2228	44/18639	0.113636363636364	0.950658968500081	0.617420923683764	1
GO:0004864	protein phosphatase inhibitor activity	6/2228	53/18639	0.113207547169811	0.947071576166119	0.619768460748846	1
GO:0051018	protein kinase A binding	6/2228	53/18639	0.113207547169811	0.947071576166119	0.619768460748846	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/2228	17/18639	0.117647058823529	0.984211637976555	0.620215397817129	1
GO:0017110	nucleoside diphosphate phosphatase activity	2/2228	17/18639	0.117647058823529	0.984211637976555	0.620215397817129	1
GO:0030169	low-density lipoprotein particle binding	2/2228	17/18639	0.117647058823529	0.984211637976555	0.620215397817129	1
GO:0038191	neuropilin binding	2/2228	17/18639	0.117647058823529	0.984211637976555	0.620215397817129	1
GO:0070402	NADPH binding	2/2228	17/18639	0.117647058823529	0.984211637976555	0.620215397817129	1
GO:1901567	fatty acid derivative binding	2/2228	17/18639	0.117647058823529	0.984211637976555	0.620215397817129	1
GO:0015179	L-amino acid transmembrane transporter activity	7/2228	62/18639	0.112903225806452	0.944525684832339	0.622516035137394	1
GO:0008013	beta-catenin binding	12/2228	106/18639	0.113207547169811	0.947071576166119	0.624543596447204	1
GO:0140299	molecular sensor activity	8/2228	71/18639	0.112676056338028	0.942625230738109	0.625469980034129	1
GO:0004857	enzyme inhibitor activity	48/2228	416/18639	0.115384615384615	0.965284491092391	0.62691645045086	1
GO:0035401	histone H3Y41 kinase activity	13/2228	115/18639	0.11304347826087	0.945699008664429	0.628159009336226	1
GO:0140801	histone H2AXY142 kinase activity	13/2228	115/18639	0.11304347826087	0.945699008664429	0.628159009336226	1
GO:0004190	aspartic-type endopeptidase activity	4/2228	36/18639	0.111111111111111	0.929533213644524	0.638615788898344	1
GO:0016409	palmitoyltransferase activity	4/2228	36/18639	0.111111111111111	0.929533213644524	0.638615788898344	1
GO:0045505	dynein intermediate chain binding	4/2228	36/18639	0.111111111111111	0.929533213644524	0.638615788898344	1
GO:0005507	copper ion binding	7/2228	63/18639	0.111111111111111	0.929533213644524	0.639722779192917	1
GO:0005385	zinc ion transmembrane transporter activity	3/2228	27/18639	0.111111111111111	0.929533213644524	0.642138920113586	1
GO:0016405	CoA-ligase activity	3/2228	27/18639	0.111111111111111	0.929533213644524	0.642138920113586	1
GO:0035255	ionotropic glutamate receptor binding	3/2228	27/18639	0.111111111111111	0.929533213644524	0.642138920113586	1
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	3/2228	27/18639	0.111111111111111	0.929533213644524	0.642138920113586	1
GO:0015101	organic cation transmembrane transporter activity	9/2228	81/18639	0.111111111111111	0.929533213644524	0.643653159739057	1
GO:0005319	lipid transporter activity	20/2228	178/18639	0.112359550561798	0.93997740705626	0.650998952309884	1
GO:0030228	lipoprotein particle receptor activity	2/2228	18/18639	0.111111111111111	0.929533213644524	0.651913081817376	1
GO:0070064	proline-rich region binding	2/2228	18/18639	0.111111111111111	0.929533213644524	0.651913081817376	1
GO:1901611	phosphatidylglycerol binding	2/2228	18/18639	0.111111111111111	0.929533213644524	0.651913081817376	1
GO:0030551	cyclic nucleotide binding	4/2228	37/18639	0.108108108108108	0.904410694356834	0.660470994897865	1
GO:0070001	aspartic-type peptidase activity	4/2228	37/18639	0.108108108108108	0.904410694356834	0.660470994897865	1
GO:0046875	ephrin receptor binding	3/2228	28/18639	0.107142857142857	0.896335598871505	0.667020594117336	1
GO:0051959	dynein light intermediate chain binding	3/2228	28/18639	0.107142857142857	0.896335598871505	0.667020594117336	1
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	3/2228	28/18639	0.107142857142857	0.896335598871505	0.667020594117336	1
GO:0031491	nucleosome binding	8/2228	74/18639	0.108108108108108	0.904410694356834	0.672483138141824	1
GO:0061749	forked DNA-dependent helicase activity	5/2228	47/18639	0.106382978723404	0.889978608808587	0.676482525060699	1
GO:0042887	amide transmembrane transporter activity	4/2228	38/18639	0.105263157894737	0.880610412926391	0.681411103903896	1
GO:0008301	DNA binding, bending	2/2228	19/18639	0.105263157894737	0.880610412926391	0.681463221366692	1
GO:0042834	peptidoglycan binding	2/2228	19/18639	0.105263157894737	0.880610412926391	0.681463221366692	1
GO:0046527	glucosyltransferase activity	2/2228	19/18639	0.105263157894737	0.880610412926391	0.681463221366692	1
GO:0120227	acyl-CoA binding	2/2228	19/18639	0.105263157894737	0.880610412926391	0.681463221366692	1
GO:0051213	dioxygenase activity	10/2228	93/18639	0.10752688172043	0.899548271268894	0.687007575924681	1
GO:0035250	UDP-galactosyltransferase activity	3/2228	29/18639	0.103448275862069	0.865427474772488	0.690612744099591	1
GO:0009378	four-way junction helicase activity	5/2228	48/18639	0.104166666666667	0.871437387791742	0.694756985181058	1
GO:0036121	double-stranded DNA helicase activity	5/2228	48/18639	0.104166666666667	0.871437387791742	0.694756985181058	1
GO:0000217	DNA secondary structure binding	4/2228	39/18639	0.102564102564103	0.858030658748792	0.701427806964848	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	4/2228	39/18639	0.102564102564103	0.858030658748792	0.701427806964848	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	14/2228	130/18639	0.107692307692308	0.900932191686231	0.701598327245986	1
GO:0042054	histone methyltransferase activity	7/2228	67/18639	0.104477611940299	0.874038693426941	0.703793167853182	1
GO:0017116	single-stranded DNA helicase activity	6/2228	58/18639	0.103448275862069	0.865427474772488	0.707106747860273	1
GO:0001614	purinergic nucleotide receptor activity	2/2228	20/18639	0.1	0.836579892280072	0.708926089154191	1
GO:0016502	nucleotide receptor activity	2/2228	20/18639	0.1	0.836579892280072	0.708926089154191	1
GO:0140939	histone H4 methyltransferase activity	2/2228	20/18639	0.1	0.836579892280072	0.708926089154191	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	13/2228	122/18639	0.10655737704918	0.891437590134503	0.712049599966434	1
GO:0015215	nucleotide transmembrane transporter activity	3/2228	30/18639	0.1	0.836579892280072	0.712922860019582	1
GO:0033612	receptor serine/threonine kinase binding	3/2228	30/18639	0.1	0.836579892280072	0.712922860019582	1
GO:0004713	protein tyrosine kinase activity	15/2228	140/18639	0.107142857142857	0.896335598871505	0.713026756671982	1
GO:0033218	amide binding	27/2228	247/18639	0.109311740890688	0.914480044192791	0.71947513120883	1
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0003796	lysozyme activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0005031	tumor necrosis factor receptor activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0005131	growth hormone receptor binding	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0005337	nucleoside transmembrane transporter activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0005381	iron ion transmembrane transporter activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0008190	eukaryotic initiation factor 4E binding	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0008519	ammonium channel activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0015187	glycine transmembrane transporter activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0015203	polyamine transmembrane transporter activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0015279	store-operated calcium channel activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0016783	sulfurtransferase activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0019911	structural constituent of myelin sheath	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0032356	oxidized DNA binding	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0035256	G protein-coupled glutamate receptor binding	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0042975	peroxisome proliferator activated receptor binding	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0043121	neurotrophin binding	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0043208	glycosphingolipid binding	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0047429	nucleoside triphosphate diphosphatase activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0051880	G-quadruplex DNA binding	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0070513	death domain binding	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0070739	protein-glutamic acid ligase activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0070740	tubulin-glutamic acid ligase activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0071723	lipopeptide binding	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0098505	G-rich strand telomeric DNA binding	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0141109	transporter activator activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:1990757	ubiquitin ligase activator activity	1/2228	10/18639	0.1	0.836579892280072	0.720113487406843	1
GO:0004896	cytokine receptor activity	10/2228	96/18639	0.104166666666667	0.871437387791742	0.725039642179896	1
GO:0016878	acid-thiol ligase activity	3/2228	31/18639	0.0967741935483871	0.809593444142005	0.733968491121648	1
GO:0047499	calcium-independent phospholipase A2 activity	3/2228	31/18639	0.0967741935483871	0.809593444142005	0.733968491121648	1
GO:0017124	SH3 domain binding	12/2228	115/18639	0.104347826086957	0.872952931074857	0.734374678562642	1
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	2/2228	21/18639	0.0952380952380952	0.796742754552449	0.734378232925861	1
GO:0005123	death receptor binding	2/2228	21/18639	0.0952380952380952	0.796742754552449	0.734378232925861	1
GO:0019200	carbohydrate kinase activity	2/2228	21/18639	0.0952380952380952	0.796742754552449	0.734378232925861	1
GO:0051428	peptide hormone receptor binding	2/2228	21/18639	0.0952380952380952	0.796742754552449	0.734378232925861	1
GO:0004812	aminoacyl-tRNA ligase activity	4/2228	41/18639	0.0975609756097561	0.816175504663485	0.738691589752693	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	4/2228	41/18639	0.0975609756097561	0.816175504663485	0.738691589752693	1
GO:0017080	sodium channel regulator activity	4/2228	41/18639	0.0975609756097561	0.816175504663485	0.738691589752693	1
GO:0016758	hexosyltransferase activity	21/2228	197/18639	0.106598984771574	0.891785671973681	0.744650336501687	1
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	6/2228	61/18639	0.0983606557377049	0.822865467816464	0.752451158405369	1
GO:0000099	sulfur amino acid transmembrane transporter activity	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0002162	dystroglycan binding	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0004016	adenylate cyclase activity	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0005114	type II transforming growth factor beta receptor binding	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0019206	nucleoside kinase activity	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0032794	GTPase activating protein binding	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0034056	estrogen response element binding	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0035252	UDP-xylosyltransferase activity	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0042285	xylosyltransferase activity	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0042608	T cell receptor binding	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0043522	leucine zipper domain binding	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0045294	alpha-catenin binding	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0047676	arachidonate-CoA ligase activity	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0048185	activin binding	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0050786	RAGE receptor binding	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0050998	nitric-oxide synthase binding	1/2228	11/18639	0.0909090909090909	0.760527174800065	0.753587487624651	1
GO:0008378	galactosyltransferase activity	3/2228	32/18639	0.09375	0.784293649012567	0.75377552221821	1
GO:0047498	calcium-dependent phospholipase A2 activity	3/2228	32/18639	0.09375	0.784293649012567	0.75377552221821	1
GO:0071813	lipoprotein particle binding	3/2228	32/18639	0.09375	0.784293649012567	0.75377552221821	1
GO:0071814	protein-lipid complex binding	3/2228	32/18639	0.09375	0.784293649012567	0.75377552221821	1
GO:0120015	sterol transfer activity	3/2228	32/18639	0.09375	0.784293649012567	0.75377552221821	1
GO:0048306	calcium-dependent protein binding	8/2228	80/18639	0.1	0.836579892280072	0.754992511354815	1
GO:0031492	nucleosomal DNA binding	4/2228	42/18639	0.0952380952380952	0.796742754552449	0.755953478872413	1
GO:0051879	Hsp90 protein binding	4/2228	42/18639	0.0952380952380952	0.796742754552449	0.755953478872413	1
GO:0008970	phospholipase A1 activity	2/2228	22/18639	0.0909090909090909	0.760527174800065	0.757907726842526	1
GO:0015377	chloride:monoatomic cation symporter activity	2/2228	22/18639	0.0909090909090909	0.760527174800065	0.757907726842526	1
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	2/2228	22/18639	0.0909090909090909	0.760527174800065	0.757907726842526	1
GO:0033691	sialic acid binding	2/2228	22/18639	0.0909090909090909	0.760527174800065	0.757907726842526	1
GO:0005080	protein kinase C binding	5/2228	52/18639	0.0961538461538462	0.804403742576992	0.760621787247244	1
GO:0030159	signaling receptor complex adaptor activity	5/2228	52/18639	0.0961538461538462	0.804403742576992	0.760621787247244	1
GO:0008194	UDP-glycosyltransferase activity	15/2228	145/18639	0.103448275862069	0.865427474772488	0.761950607178754	1
GO:0004620	phospholipase activity	11/2228	109/18639	0.100917431192661	0.844254937163375	0.768032208494071	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	4/2228	43/18639	0.0930232558139535	0.778213853283788	0.772320075419417	1
GO:0019239	deaminase activity	3/2228	33/18639	0.0909090909090909	0.760527174800065	0.772376624078735	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	9/2228	91/18639	0.0989010989010989	0.82738670665062	0.774390521135979	1
GO:1901505	carbohydrate derivative transmembrane transporter activity	5/2228	53/18639	0.0943396226415094	0.789226313471766	0.775294008757494	1
GO:0005283	amino acid:sodium symporter activity	2/2228	23/18639	0.0869565217391304	0.727460775895715	0.779610324737786	1
GO:0016493	C-C chemokine receptor activity	2/2228	23/18639	0.0869565217391304	0.727460775895715	0.779610324737786	1
GO:0016849	phosphorus-oxygen lyase activity	2/2228	23/18639	0.0869565217391304	0.727460775895715	0.779610324737786	1
GO:0031681	G-protein beta-subunit binding	2/2228	23/18639	0.0869565217391304	0.727460775895715	0.779610324737786	1
GO:0042171	lysophosphatidic acid acyltransferase activity	2/2228	23/18639	0.0869565217391304	0.727460775895715	0.779610324737786	1
GO:0071617	lysophospholipid acyltransferase activity	2/2228	23/18639	0.0869565217391304	0.727460775895715	0.779610324737786	1
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0003720	telomerase activity	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0003995	acyl-CoA dehydrogenase activity	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0005025	transforming growth factor beta receptor activity, type I	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0005026	transforming growth factor beta receptor activity, type II	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0005078	MAP-kinase scaffold activity	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0015132	prostaglandin transmembrane transporter activity	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0015166	polyol transmembrane transporter activity	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0015269	calcium-activated potassium channel activity	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0016208	AMP binding	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0016273	arginine N-methyltransferase activity	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0016274	protein-arginine N-methyltransferase activity	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0016361	activin receptor activity, type I	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0016362	activin receptor activity, type II	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0016840	carbon-nitrogen lyase activity	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0017002	activin receptor activity	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0031543	peptidyl-proline dioxygenase activity	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0035497	cAMP response element binding	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0043047	single-stranded telomeric DNA binding	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0070679	inositol 1,4,5 trisphosphate binding	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:1990459	transferrin receptor binding	1/2228	12/18639	0.0833333333333333	0.697149910233393	0.783059630504846	1
GO:0004521	RNA endonuclease activity	7/2228	73/18639	0.0958904109589041	0.802199896706918	0.784820621747311	1
GO:0015485	cholesterol binding	5/2228	54/18639	0.0925925925925926	0.774611011370437	0.789265818469794	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	5/2228	54/18639	0.0925925925925926	0.774611011370437	0.789265818469794	1
GO:0050661	NADP binding	5/2228	54/18639	0.0925925925925926	0.774611011370437	0.789265818469794	1
GO:0051427	hormone receptor binding	3/2228	34/18639	0.0882352941176471	0.738158728482416	0.789809872174302	1
GO:0090482	vitamin transmembrane transporter activity	3/2228	34/18639	0.0882352941176471	0.738158728482416	0.789809872174302	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	13/2228	130/18639	0.1	0.836579892280072	0.792166104646137	1
GO:0005315	phosphate transmembrane transporter activity	2/2228	24/18639	0.0833333333333333	0.697149910233393	0.799586367654378	1
GO:0030552	cAMP binding	2/2228	24/18639	0.0833333333333333	0.697149910233393	0.799586367654378	1
GO:0140612	DNA damage sensor activity	2/2228	24/18639	0.0833333333333333	0.697149910233393	0.799586367654378	1
GO:0005253	monoatomic anion channel activity	10/2228	103/18639	0.0970873786407767	0.812213487650555	0.801436004685929	1
GO:0046915	transition metal ion transmembrane transporter activity	4/2228	45/18639	0.0888888888888889	0.743626570915619	0.802445130720453	1
GO:0008374	O-acyltransferase activity	5/2228	55/18639	0.0909090909090909	0.760527174800065	0.802550472252611	1
GO:0002161	aminoacyl-tRNA editing activity	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0003964	RNA-directed DNA polymerase activity	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0008035	high-density lipoprotein particle binding	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0008253	5'-nucleotidase activity	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0019104	DNA N-glycosylase activity	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0031994	insulin-like growth factor I binding	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0035325	Toll-like receptor binding	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0035673	oligopeptide transmembrane transporter activity	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0043560	insulin receptor substrate binding	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0045159	myosin II binding	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0046974	histone H3K9 methyltransferase activity	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0070123	transforming growth factor beta receptor activity, type III	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0071714	icosanoid transmembrane transporter activity	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0089720	caspase binding	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0140333	glycerophospholipid flippase activity	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/2228	13/18639	0.0769230769230769	0.643522994061594	0.809008153790142	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	13/2228	132/18639	0.0984848484848485	0.823904439366737	0.809462127820883	1
GO:0046943	carboxylic acid transmembrane transporter activity	19/2228	188/18639	0.101063829787234	0.845479678368158	0.813980995256024	1
GO:0030276	clathrin binding	4/2228	46/18639	0.0869565217391304	0.727460775895715	0.8162501164236	1
GO:0001848	complement binding	2/2228	25/18639	0.08	0.669263913824057	0.817938320419541	1
GO:0003707	nuclear steroid receptor activity	2/2228	25/18639	0.08	0.669263913824057	0.817938320419541	1
GO:0005537	D-mannose binding	2/2228	25/18639	0.08	0.669263913824057	0.817938320419541	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	2/2228	25/18639	0.08	0.669263913824057	0.817938320419541	1
GO:0120020	cholesterol transfer activity	2/2228	25/18639	0.08	0.669263913824057	0.817938320419541	1
GO:0098631	cell adhesion mediator activity	7/2228	76/18639	0.0921052631578947	0.770534111310592	0.818561575818355	1
GO:0005342	organic acid transmembrane transporter activity	19/2228	189/18639	0.100529100529101	0.841006240916474	0.82085943839108	1
GO:0004033	aldo-keto reductase (NADPH) activity	3/2228	36/18639	0.0833333333333333	0.697149910233393	0.821344956183332	1
GO:0050660	flavin adenine dinucleotide binding	8/2228	86/18639	0.0930232558139535	0.778213853283788	0.821626785648993	1
GO:0004705	JUN kinase activity	1/2228	14/18639	0.0714285714285714	0.597557065914337	0.831854166533381	1
GO:0008191	metalloendopeptidase inhibitor activity	1/2228	14/18639	0.0714285714285714	0.597557065914337	0.831854166533381	1
GO:0008195	phosphatidate phosphatase activity	1/2228	14/18639	0.0714285714285714	0.597557065914337	0.831854166533381	1
GO:0015386	potassium:proton antiporter activity	1/2228	14/18639	0.0714285714285714	0.597557065914337	0.831854166533381	1
GO:0031404	chloride ion binding	1/2228	14/18639	0.0714285714285714	0.597557065914337	0.831854166533381	1
GO:0034236	protein kinase A catalytic subunit binding	1/2228	14/18639	0.0714285714285714	0.597557065914337	0.831854166533381	1
GO:0043176	amine binding	1/2228	14/18639	0.0714285714285714	0.597557065914337	0.831854166533381	1
GO:0044548	S100 protein binding	1/2228	14/18639	0.0714285714285714	0.597557065914337	0.831854166533381	1
GO:0061783	peptidoglycan muralytic activity	1/2228	14/18639	0.0714285714285714	0.597557065914337	0.831854166533381	1
GO:0070742	C2H2 zinc finger domain binding	1/2228	14/18639	0.0714285714285714	0.597557065914337	0.831854166533381	1
GO:0098821	BMP receptor activity	1/2228	14/18639	0.0714285714285714	0.597557065914337	0.831854166533381	1
GO:0098847	sequence-specific single stranded DNA binding	1/2228	14/18639	0.0714285714285714	0.597557065914337	0.831854166533381	1
GO:1901612	cardiolipin binding	1/2228	14/18639	0.0714285714285714	0.597557065914337	0.831854166533381	1
GO:0001637	G protein-coupled chemoattractant receptor activity	2/2228	26/18639	0.0769230769230769	0.643522994061594	0.83476883116389	1
GO:0004950	chemokine receptor activity	2/2228	26/18639	0.0769230769230769	0.643522994061594	0.83476883116389	1
GO:0008157	protein phosphatase 1 binding	2/2228	26/18639	0.0769230769230769	0.643522994061594	0.83476883116389	1
GO:0030247	polysaccharide binding	2/2228	26/18639	0.0769230769230769	0.643522994061594	0.83476883116389	1
GO:0043548	phosphatidylinositol 3-kinase binding	2/2228	26/18639	0.0769230769230769	0.643522994061594	0.83476883116389	1
GO:0050750	low-density lipoprotein particle receptor binding	2/2228	26/18639	0.0769230769230769	0.643522994061594	0.83476883116389	1
GO:0022829	wide pore channel activity	3/2228	37/18639	0.0810810810810811	0.678308020767626	0.835539717473226	1
GO:0023023	MHC protein complex binding	3/2228	37/18639	0.0810810810810811	0.678308020767626	0.835539717473226	1
GO:0004519	endonuclease activity	12/2228	127/18639	0.094488188976378	0.790469189555973	0.84441510608014	1
GO:0005496	steroid binding	10/2228	108/18639	0.0925925925925926	0.774611011370437	0.84555327830905	1
GO:0015370	solute:sodium symporter activity	7/2228	79/18639	0.0886075949367089	0.741273322273481	0.848029297786011	1
GO:0023026	MHC class II protein complex binding	2/2228	27/18639	0.0740740740740741	0.619688809096349	0.850179224047914	1
GO:0004089	carbonate dehydratase activity	1/2228	15/18639	0.0666666666666667	0.557719928186714	0.851968470799884	1
GO:0004129	cytochrome-c oxidase activity	1/2228	15/18639	0.0666666666666667	0.557719928186714	0.851968470799884	1
GO:0004467	long-chain fatty acid-CoA ligase activity	1/2228	15/18639	0.0666666666666667	0.557719928186714	0.851968470799884	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/2228	15/18639	0.0666666666666667	0.557719928186714	0.851968470799884	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/2228	15/18639	0.0666666666666667	0.557719928186714	0.851968470799884	1
GO:0008242	omega peptidase activity	1/2228	15/18639	0.0666666666666667	0.557719928186714	0.851968470799884	1
GO:0008252	nucleotidase activity	1/2228	15/18639	0.0666666666666667	0.557719928186714	0.851968470799884	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/2228	15/18639	0.0666666666666667	0.557719928186714	0.851968470799884	1
GO:0031005	filamin binding	1/2228	15/18639	0.0666666666666667	0.557719928186714	0.851968470799884	1
GO:0033130	acetylcholine receptor binding	1/2228	15/18639	0.0666666666666667	0.557719928186714	0.851968470799884	1
GO:0140776	protein-containing complex destabilizing activity	1/2228	15/18639	0.0666666666666667	0.557719928186714	0.851968470799884	1
GO:0035254	glutamate receptor binding	4/2228	49/18639	0.0816326530612245	0.682922361044957	0.852960291230695	1
GO:0016782	transferase activity, transferring sulphur-containing groups	6/2228	70/18639	0.0857142857142857	0.717068479097204	0.857310164475523	1
GO:0070851	growth factor receptor binding	13/2228	139/18639	0.0935251798561151	0.782412848895031	0.86166920025524	1
GO:0005242	inward rectifier potassium channel activity	2/2228	28/18639	0.0714285714285714	0.597557065914337	0.864268349427189	1
GO:0016866	intramolecular transferase activity	2/2228	28/18639	0.0714285714285714	0.597557065914337	0.864268349427189	1
GO:0045499	chemorepellent activity	2/2228	28/18639	0.0714285714285714	0.597557065914337	0.864268349427189	1
GO:0008509	monoatomic anion transmembrane transporter activity	14/2228	149/18639	0.0939597315436242	0.786048220934296	0.864652937804635	1
GO:0005543	phospholipid binding	52/2228	497/18639	0.104627766599598	0.875294857113958	0.867131313593016	1
GO:0004707	MAP kinase activity	1/2228	16/18639	0.0625	0.522862432675045	0.869677569116994	1
GO:0004708	MAP kinase kinase activity	1/2228	16/18639	0.0625	0.522862432675045	0.869677569116994	1
GO:0005024	transforming growth factor beta receptor activity	1/2228	16/18639	0.0625	0.522862432675045	0.869677569116994	1
GO:0005149	interleukin-1 receptor binding	1/2228	16/18639	0.0625	0.522862432675045	0.869677569116994	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/2228	16/18639	0.0625	0.522862432675045	0.869677569116994	1
GO:0015378	sodium:chloride symporter activity	1/2228	16/18639	0.0625	0.522862432675045	0.869677569116994	1
GO:0016675	oxidoreductase activity, acting on a heme group of donors	1/2228	16/18639	0.0625	0.522862432675045	0.869677569116994	1
GO:0030275	LRR domain binding	1/2228	16/18639	0.0625	0.522862432675045	0.869677569116994	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/2228	16/18639	0.0625	0.522862432675045	0.869677569116994	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/2228	16/18639	0.0625	0.522862432675045	0.869677569116994	1
GO:0140327	flippase activity	1/2228	16/18639	0.0625	0.522862432675045	0.869677569116994	1
GO:0071949	FAD binding	3/2228	40/18639	0.075	0.627434919210054	0.872420187464335	1
GO:0004181	metallocarboxypeptidase activity	2/2228	29/18639	0.0689655172413793	0.576951649848325	0.877131727599604	1
GO:0005416	amino acid:monoatomic cation symporter activity	2/2228	29/18639	0.0689655172413793	0.576951649848325	0.877131727599604	1
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	3/2228	41/18639	0.0731707317073171	0.612131628497613	0.882977708336307	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/2228	17/18639	0.0588235294117647	0.492105818988278	0.885268954823236	1
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/2228	17/18639	0.0588235294117647	0.492105818988278	0.885268954823236	1
GO:0005092	GDP-dissociation inhibitor activity	1/2228	17/18639	0.0588235294117647	0.492105818988278	0.885268954823236	1
GO:0008484	sulfuric ester hydrolase activity	1/2228	17/18639	0.0588235294117647	0.492105818988278	0.885268954823236	1
GO:0009881	photoreceptor activity	1/2228	17/18639	0.0588235294117647	0.492105818988278	0.885268954823236	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/2228	17/18639	0.0588235294117647	0.492105818988278	0.885268954823236	1
GO:0019198	transmembrane receptor protein phosphatase activity	1/2228	17/18639	0.0588235294117647	0.492105818988278	0.885268954823236	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/2228	17/18639	0.0588235294117647	0.492105818988278	0.885268954823236	1
GO:0036041	long-chain fatty acid binding	1/2228	17/18639	0.0588235294117647	0.492105818988278	0.885268954823236	1
GO:0070492	oligosaccharide binding	1/2228	17/18639	0.0588235294117647	0.492105818988278	0.885268954823236	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/2228	30/18639	0.0666666666666667	0.557719928186714	0.888860932426749	1
GO:0048029	monosaccharide binding	6/2228	74/18639	0.0810810810810811	0.678308020767626	0.890504831999416	1
GO:0008146	sulfotransferase activity	4/2228	53/18639	0.0754716981132075	0.631381050777413	0.892056623556418	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/2228	18/18639	0.0555555555555556	0.464766606822262	0.898995770882404	1
GO:0008409	5'-3' exonuclease activity	1/2228	18/18639	0.0555555555555556	0.464766606822262	0.898995770882404	1
GO:0015172	acidic amino acid transmembrane transporter activity	1/2228	18/18639	0.0555555555555556	0.464766606822262	0.898995770882404	1
GO:0015373	monoatomic anion:sodium symporter activity	1/2228	18/18639	0.0555555555555556	0.464766606822262	0.898995770882404	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/2228	18/18639	0.0555555555555556	0.464766606822262	0.898995770882404	1
GO:0017075	syntaxin-1 binding	1/2228	18/18639	0.0555555555555556	0.464766606822262	0.898995770882404	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/2228	18/18639	0.0555555555555556	0.464766606822262	0.898995770882404	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/2228	31/18639	0.0645161290322581	0.539728962761337	0.899543169758135	1
GO:0005452	solute:inorganic anion antiporter activity	2/2228	31/18639	0.0645161290322581	0.539728962761337	0.899543169758135	1
GO:0008327	methyl-CpG binding	2/2228	31/18639	0.0645161290322581	0.539728962761337	0.899543169758135	1
GO:0016411	acylglycerol O-acyltransferase activity	2/2228	31/18639	0.0645161290322581	0.539728962761337	0.899543169758135	1
GO:0070325	lipoprotein particle receptor binding	2/2228	31/18639	0.0645161290322581	0.539728962761337	0.899543169758135	1
GO:0038024	cargo receptor activity	5/2228	65/18639	0.0769230769230769	0.643522994061594	0.901646707544115	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	7/2228	86/18639	0.0813953488372093	0.680937121623314	0.901885953586684	1
GO:0015085	calcium ion transmembrane transporter activity	13/2228	147/18639	0.0884353741496599	0.739832557798703	0.906812787079027	1
GO:0098632	cell-cell adhesion mediator activity	4/2228	55/18639	0.0727272727272727	0.608421739840052	0.907944940175955	1
GO:0008235	metalloexopeptidase activity	5/2228	66/18639	0.0757575757575758	0.633772645666721	0.908647304576713	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/2228	19/18639	0.0526315789473684	0.440305206463196	0.911080912522166	1
GO:0005229	intracellularly calcium-gated chloride channel activity	1/2228	19/18639	0.0526315789473684	0.440305206463196	0.911080912522166	1
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/2228	19/18639	0.0526315789473684	0.440305206463196	0.911080912522166	1
GO:0005520	insulin-like growth factor binding	1/2228	19/18639	0.0526315789473684	0.440305206463196	0.911080912522166	1
GO:0008574	plus-end-directed microtubule motor activity	1/2228	19/18639	0.0526315789473684	0.440305206463196	0.911080912522166	1
GO:0015245	fatty acid transmembrane transporter activity	1/2228	19/18639	0.0526315789473684	0.440305206463196	0.911080912522166	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/2228	19/18639	0.0526315789473684	0.440305206463196	0.911080912522166	1
GO:0022821	solute:potassium antiporter activity	1/2228	19/18639	0.0526315789473684	0.440305206463196	0.911080912522166	1
GO:0042577	lipid phosphatase activity	1/2228	19/18639	0.0526315789473684	0.440305206463196	0.911080912522166	1
GO:0141147	intracellularly calcium-gated channel activity	1/2228	19/18639	0.0526315789473684	0.440305206463196	0.911080912522166	1
GO:0005516	calmodulin binding	19/2228	207/18639	0.0917874396135266	0.767875263445477	0.914831316896755	1
GO:0030170	pyridoxal phosphate binding	4/2228	56/18639	0.0714285714285714	0.597557065914337	0.91508198732663	1
GO:0170055	lipid transmembrane transporter activity	4/2228	56/18639	0.0714285714285714	0.597557065914337	0.91508198732663	1
GO:0030296	protein tyrosine kinase activator activity	2/2228	33/18639	0.0606060606060606	0.507018116533377	0.918092263820929	1
GO:0004175	endopeptidase activity	40/2228	405/18639	0.0987654320987654	0.826251745461799	0.919141784752328	1
GO:0016298	lipase activity	11/2228	130/18639	0.0846153846153846	0.707875293467753	0.919902211908423	1
GO:0070279	vitamin B6 binding	4/2228	57/18639	0.0701754385964912	0.587073608617594	0.92172051314798	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/2228	20/18639	0.05	0.418289946140036	0.921720640067849	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/2228	20/18639	0.05	0.418289946140036	0.921720640067849	1
GO:0031418	L-ascorbic acid binding	1/2228	20/18639	0.05	0.418289946140036	0.921720640067849	1
GO:0140664	ATP-dependent DNA damage sensor activity	1/2228	20/18639	0.05	0.418289946140036	0.921720640067849	1
GO:0004180	carboxypeptidase activity	3/2228	46/18639	0.0652173913043478	0.545595581921786	0.924897049319777	1
GO:1902936	phosphatidylinositol bisphosphate binding	9/2228	111/18639	0.0810810810810811	0.678308020767626	0.925719224537454	1
GO:0008376	acetylgalactosaminyltransferase activity	2/2228	34/18639	0.0588235294117647	0.492105818988278	0.926109913298844	1
GO:0072341	modified amino acid binding	7/2228	91/18639	0.0769230769230769	0.643522994061594	0.929562148227873	1
GO:0005200	structural constituent of cytoskeleton	9/2228	112/18639	0.0803571428571429	0.672251699153629	0.930150883309657	1
GO:0001846	opsonin binding	1/2228	21/18639	0.0476190476190476	0.398371377276225	0.931087760424948	1
GO:0009975	cyclase activity	1/2228	21/18639	0.0476190476190476	0.398371377276225	0.931087760424948	1
GO:0010314	phosphatidylinositol-5-phosphate binding	1/2228	21/18639	0.0476190476190476	0.398371377276225	0.931087760424948	1
GO:0015125	bile acid transmembrane transporter activity	1/2228	21/18639	0.0476190476190476	0.398371377276225	0.931087760424948	1
GO:0061891	calcium ion sensor activity	1/2228	21/18639	0.0476190476190476	0.398371377276225	0.931087760424948	1
GO:0070182	DNA polymerase binding	1/2228	21/18639	0.0476190476190476	0.398371377276225	0.931087760424948	1
GO:0008238	exopeptidase activity	8/2228	102/18639	0.0784313725490196	0.65614109198437	0.931801633819175	1
GO:0015171	amino acid transmembrane transporter activity	8/2228	102/18639	0.0784313725490196	0.65614109198437	0.931801633819175	1
GO:0003774	cytoskeletal motor activity	13/2228	153/18639	0.0849673202614379	0.710819516316401	0.932015950271477	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	5/2228	70/18639	0.0714285714285714	0.597557065914337	0.932461724866777	1
GO:0005343	organic acid:sodium symporter activity	2/2228	35/18639	0.0571428571428571	0.47804565273147	0.933382179221425	1
GO:0052689	carboxylic ester hydrolase activity	7/2228	92/18639	0.0760869565217391	0.63652817890875	0.934194557946298	1
GO:0030246	carbohydrate binding	26/2228	280/18639	0.0928571428571429	0.776824185688638	0.934596175592091	1
GO:0019955	cytokine binding	12/2228	144/18639	0.0833333333333333	0.697149910233393	0.935772888398667	1
GO:0016881	acid-amino acid ligase activity	1/2228	22/18639	0.0454545454545455	0.380263587400033	0.939334428690778	1
GO:0140784	metal ion sensor activity	1/2228	22/18639	0.0454545454545455	0.380263587400033	0.939334428690778	1
GO:1901981	phosphatidylinositol phosphate binding	16/2228	185/18639	0.0864864864864865	0.723528555485468	0.939431313584333	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/2228	36/18639	0.0555555555555556	0.464766606822262	0.939972604106019	1
GO:0005518	collagen binding	5/2228	72/18639	0.0694444444444444	0.580958258527828	0.942148542244061	1
GO:0015026	coreceptor activity	4/2228	61/18639	0.0655737704918033	0.548576978544309	0.943848217437722	1
GO:0061134	peptidase regulator activity	20/2228	226/18639	0.0884955752212389	0.740336187858471	0.94441866410507	1
GO:0015294	solute:monoatomic cation symporter activity	9/2228	116/18639	0.0775862068965517	0.649070606079366	0.945662326811459	1
GO:0042805	actinin binding	2/2228	37/18639	0.0540540540540541	0.452205347178417	0.945940197627893	1
GO:0000295	adenine nucleotide transmembrane transporter activity	1/2228	23/18639	0.0434782608695652	0.363730387947857	0.946594615234095	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/2228	23/18639	0.0434782608695652	0.363730387947857	0.946594615234095	1
GO:0004602	glutathione peroxidase activity	1/2228	23/18639	0.0434782608695652	0.363730387947857	0.946594615234095	1
GO:0005212	structural constituent of eye lens	1/2228	23/18639	0.0434782608695652	0.363730387947857	0.946594615234095	1
GO:0017134	fibroblast growth factor binding	1/2228	23/18639	0.0434782608695652	0.363730387947857	0.946594615234095	1
GO:0015291	secondary active transmembrane transporter activity	26/2228	287/18639	0.0905923344947735	0.757877254330379	0.951261198996185	1
GO:0016597	amino acid binding	3/2228	51/18639	0.0588235294117647	0.492105818988278	0.952612475424376	1
GO:0004622	lysophospholipase activity	1/2228	24/18639	0.0416666666666667	0.348574955116697	0.952986278172344	1
GO:0005540	hyaluronic acid binding	1/2228	24/18639	0.0416666666666667	0.348574955116697	0.952986278172344	1
GO:0015149	hexose transmembrane transporter activity	1/2228	24/18639	0.0416666666666667	0.348574955116697	0.952986278172344	1
GO:0015295	solute:proton symporter activity	1/2228	24/18639	0.0416666666666667	0.348574955116697	0.952986278172344	1
GO:0030215	semaphorin receptor binding	1/2228	24/18639	0.0416666666666667	0.348574955116697	0.952986278172344	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/2228	24/18639	0.0416666666666667	0.348574955116697	0.952986278172344	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/2228	24/18639	0.0416666666666667	0.348574955116697	0.952986278172344	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/2228	24/18639	0.0416666666666667	0.348574955116697	0.952986278172344	1
GO:0055056	D-glucose transmembrane transporter activity	1/2228	24/18639	0.0416666666666667	0.348574955116697	0.952986278172344	1
GO:0016209	antioxidant activity	6/2228	86/18639	0.0697674418604651	0.583660389962841	0.953503579122847	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	15/2228	181/18639	0.0828729281767956	0.693298253270778	0.955677209245724	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	3/2228	52/18639	0.0576923076923077	0.482642245546195	0.956859503466191	1
GO:0000030	mannosyltransferase activity	1/2228	25/18639	0.04	0.334631956912029	0.958613276412044	1
GO:0005251	delayed rectifier potassium channel activity	1/2228	25/18639	0.04	0.334631956912029	0.958613276412044	1
GO:0015271	outward rectifier potassium channel activity	1/2228	25/18639	0.04	0.334631956912029	0.958613276412044	1
GO:0005262	calcium channel activity	10/2228	131/18639	0.0763358778625954	0.638610604793948	0.959174106053781	1
GO:0005227	calcium-activated cation channel activity	1/2228	26/18639	0.0384615384615385	0.321761497030797	0.96356705422197	1
GO:0015145	monosaccharide transmembrane transporter activity	1/2228	26/18639	0.0384615384615385	0.321761497030797	0.96356705422197	1
GO:0015216	purine nucleotide transmembrane transporter activity	1/2228	26/18639	0.0384615384615385	0.321761497030797	0.96356705422197	1
GO:0022832	voltage-gated channel activity	14/2228	175/18639	0.08	0.669263913824057	0.964823151363285	1
GO:0005044	scavenger receptor activity	1/2228	27/18639	0.037037037037037	0.309844404548175	0.96792812461328	1
GO:0005104	fibroblast growth factor receptor binding	1/2228	27/18639	0.037037037037037	0.309844404548175	0.96792812461328	1
GO:0015252	proton channel activity	1/2228	27/18639	0.037037037037037	0.309844404548175	0.96792812461328	1
GO:0008307	structural constituent of muscle	2/2228	42/18639	0.0476190476190476	0.398371377276225	0.968207463461355	1
GO:0042056	chemoattractant activity	2/2228	42/18639	0.0476190476190476	0.398371377276225	0.968207463461355	1
GO:0043178	alcohol binding	6/2228	92/18639	0.0652173913043478	0.545595581921786	0.970605513600105	1
GO:0008514	organic anion transmembrane transporter activity	23/2228	269/18639	0.0855018587360595	0.715291357711585	0.970805195261772	1
GO:0051119	sugar transmembrane transporter activity	1/2228	28/18639	0.0357142857142857	0.298778532957168	0.971767375546098	1
GO:0003785	actin monomer binding	1/2228	29/18639	0.0344827586206897	0.288475824924163	0.975147220115616	1
GO:0043236	laminin binding	1/2228	29/18639	0.0344827586206897	0.288475824924163	0.975147220115616	1
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	1/2228	29/18639	0.0344827586206897	0.288475824924163	0.975147220115616	1
GO:0019842	vitamin binding	11/2228	150/18639	0.0733333333333333	0.613491921005386	0.976136015349991	1
GO:0005254	chloride channel activity	5/2228	83/18639	0.0602409638554217	0.503963790530164	0.97627842802452	1
GO:0005178	integrin binding	12/2228	161/18639	0.0745341614906832	0.623537807910613	0.976656115615659	1
GO:0001965	G-protein alpha-subunit binding	1/2228	30/18639	0.0333333333333333	0.278859964093357	0.978122609346266	1
GO:0022839	monoatomic ion-gated channel activity	1/2228	30/18639	0.0333333333333333	0.278859964093357	0.978122609346266	1
GO:0005126	cytokine receptor binding	23/2228	275/18639	0.0836363636363636	0.69968500081606	0.978249498547553	1
GO:0005244	voltage-gated monoatomic ion channel activity	13/2228	173/18639	0.0751445086705202	0.628643849690227	0.978627153213107	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/2228	46/18639	0.0434782608695652	0.363730387947857	0.979366940205731	1
GO:0017147	Wnt-protein binding	1/2228	31/18639	0.032258064516129	0.269864481380668	0.980741923999204	1
GO:0005506	iron ion binding	11/2228	154/18639	0.0714285714285714	0.597557065914337	0.981632082772219	1
GO:0015103	inorganic anion transmembrane transporter activity	12/2228	165/18639	0.0727272727272727	0.608421739840052	0.9818991558875	1
GO:0015106	bicarbonate transmembrane transporter activity	1/2228	32/18639	0.03125	0.261431216337522	0.983047759840228	1
GO:0032266	phosphatidylinositol-3-phosphate binding	2/2228	48/18639	0.0416666666666667	0.348574955116697	0.983414672006151	1
GO:0038187	pattern recognition receptor activity	2/2228	48/18639	0.0416666666666667	0.348574955116697	0.983414672006151	1
GO:0015293	symporter activity	10/2228	146/18639	0.0684931506849315	0.572999926219227	0.984947513326415	1
GO:0042923	neuropeptide binding	1/2228	33/18639	0.0303030303030303	0.253509058266688	0.985077619090831	1
GO:1901682	sulfur compound transmembrane transporter activity	3/2228	63/18639	0.0476190476190476	0.398371377276225	0.985143758771993	1
GO:0019838	growth factor binding	9/2228	136/18639	0.0661764705882353	0.553619046361812	0.986118203317793	1
GO:0004536	DNA nuclease activity	3/2228	64/18639	0.046875	0.392146824506284	0.986551725721746	1
GO:0048020	CCR chemokine receptor binding	2/2228	50/18639	0.04	0.334631956912029	0.9866861158664	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/2228	34/18639	0.0294117647058824	0.246052909494139	0.986864519266346	1
GO:0019825	oxygen binding	1/2228	34/18639	0.0294117647058824	0.246052909494139	0.986864519266346	1
GO:0005544	calcium-dependent phospholipid binding	2/2228	53/18639	0.0377358490566038	0.315690525388706	0.990446273409343	1
GO:0015081	sodium ion transmembrane transporter activity	11/2228	164/18639	0.0670731707317073	0.561120659456146	0.990691477963912	1
GO:0043394	proteoglycan binding	1/2228	37/18639	0.027027027027027	0.226102673589209	0.9910411870759	1
GO:0015108	chloride transmembrane transporter activity	7/2228	121/18639	0.0578512396694215	0.483971838509133	0.992586817846934	1
GO:0140375	immune receptor activity	10/2228	156/18639	0.0641025641025641	0.536269161717995	0.992616452748308	1
GO:0004601	peroxidase activity	2/2228	57/18639	0.0350877192982456	0.293536804308797	0.993886364666432	1
GO:0015144	carbohydrate transmembrane transporter activity	1/2228	40/18639	0.025	0.209144973070018	0.993890208714864	1
GO:0071855	neuropeptide receptor binding	1/2228	40/18639	0.025	0.209144973070018	0.993890208714864	1
GO:0042169	SH2 domain binding	1/2228	41/18639	0.024390243902439	0.204043876165871	0.994622109084953	1
GO:0001786	phosphatidylserine binding	2/2228	59/18639	0.0338983050847458	0.283586404162736	0.99511684025209	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	2/2228	59/18639	0.0338983050847458	0.283586404162736	0.99511684025209	1
GO:0051015	actin filament binding	14/2228	209/18639	0.0669856459330144	0.560388444589522	0.995822685615853	1
GO:0005245	voltage-gated calcium channel activity	1/2228	43/18639	0.0232558139534884	0.194553463320947	0.995833477970205	1
GO:0042562	hormone binding	4/2228	94/18639	0.0425531914893617	0.355991443523435	0.997317609375454	1
GO:0005504	fatty acid binding	1/2228	47/18639	0.0212765957446809	0.177995721761717	0.997499315388607	1
GO:0099095	ligand-gated monoatomic anion channel activity	1/2228	47/18639	0.0212765957446809	0.177995721761717	0.997499315388607	1
GO:0008236	serine-type peptidase activity	12/2228	194/18639	0.0618556701030928	0.51747209831757	0.997554138606848	1
GO:0015079	potassium ion transmembrane transporter activity	9/2228	160/18639	0.05625	0.47057618940754	0.997783357756329	1
GO:0008188	neuropeptide receptor activity	1/2228	48/18639	0.0208333333333333	0.174287477558348	0.997798988652064	1
GO:0008237	metallopeptidase activity	11/2228	184/18639	0.0597826086956522	0.500129283428304	0.997829320351741	1
GO:0061135	endopeptidase regulator activity	11/2228	184/18639	0.0597826086956522	0.500129283428304	0.997829320351741	1
GO:0016500	protein-hormone receptor activity	2/2228	67/18639	0.0298507462686567	0.249725340979126	0.998030065116097	1
GO:0050840	extracellular matrix binding	2/2228	67/18639	0.0298507462686567	0.249725340979126	0.998030065116097	1
GO:0005004	GPI-linked ephrin receptor activity	1/2228	49/18639	0.0204081632653061	0.170730590261239	0.998062764311426	1
GO:0005008	hepatocyte growth factor receptor activity	1/2228	49/18639	0.0204081632653061	0.170730590261239	0.998062764311426	1
GO:0005009	insulin receptor activity	1/2228	49/18639	0.0204081632653061	0.170730590261239	0.998062764311426	1
GO:0005011	macrophage colony-stimulating factor receptor activity	1/2228	49/18639	0.0204081632653061	0.170730590261239	0.998062764311426	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/2228	49/18639	0.0204081632653061	0.170730590261239	0.998062764311426	1
GO:0005020	stem cell factor receptor activity	1/2228	49/18639	0.0204081632653061	0.170730590261239	0.998062764311426	1
GO:0008288	boss receptor activity	1/2228	49/18639	0.0204081632653061	0.170730590261239	0.998062764311426	1
GO:0036332	placental growth factor receptor activity	1/2228	49/18639	0.0204081632653061	0.170730590261239	0.998062764311426	1
GO:0038062	protein tyrosine kinase collagen receptor activity	1/2228	49/18639	0.0204081632653061	0.170730590261239	0.998062764311426	1
GO:0060175	brain-derived neurotrophic factor receptor activity	1/2228	49/18639	0.0204081632653061	0.170730590261239	0.998062764311426	1
GO:0017171	serine hydrolase activity	12/2228	198/18639	0.0606060606060606	0.507018116533377	0.998179718802378	1
GO:0005249	voltage-gated potassium channel activity	4/2228	98/18639	0.0408163265306122	0.341461180522478	0.998193824132881	1
GO:0031406	carboxylic acid binding	11/2228	187/18639	0.0588235294117647	0.492105818988278	0.998272447163586	1
GO:0005006	epidermal growth factor receptor activity	1/2228	50/18639	0.02	0.167315978456014	0.998294940810304	1
GO:0005007	fibroblast growth factor receptor activity	1/2228	50/18639	0.02	0.167315978456014	0.998294940810304	1
GO:0005017	platelet-derived growth factor receptor activity	1/2228	50/18639	0.02	0.167315978456014	0.998294940810304	1
GO:0005019	platelet-derived growth factor beta-receptor activity	1/2228	50/18639	0.02	0.167315978456014	0.998294940810304	1
GO:0005010	insulin-like growth factor receptor activity	1/2228	51/18639	0.0196078431372549	0.164035272996092	0.998499302092495	1
GO:0005021	vascular endothelial growth factor receptor activity	1/2228	51/18639	0.0196078431372549	0.164035272996092	0.998499302092495	1
GO:0005030	neurotrophin receptor activity	1/2228	51/18639	0.0196078431372549	0.164035272996092	0.998499302092495	1
GO:0043177	organic acid binding	11/2228	189/18639	0.0582010582010582	0.486898350004275	0.998518355616699	1
GO:0020037	heme binding	7/2228	142/18639	0.0492957746478873	0.412398538447923	0.998748594209712	1
GO:0005003	ephrin receptor activity	1/2228	53/18639	0.0188679245283019	0.157845262694353	0.998837504270981	1
GO:0005005	transmembrane-ephrin receptor activity	1/2228	53/18639	0.0188679245283019	0.157845262694353	0.998837504270981	1
GO:0017046	peptide hormone binding	1/2228	53/18639	0.0188679245283019	0.157845262694353	0.998837504270981	1
GO:0038064	collagen receptor activity	1/2228	53/18639	0.0188679245283019	0.157845262694353	0.998837504270981	1
GO:0042379	chemokine receptor binding	2/2228	72/18639	0.0277777777777778	0.232383303411131	0.998890033130252	1
GO:1901681	sulfur compound binding	18/2228	275/18639	0.0654545454545455	0.547579565856047	0.999023481478103	1
GO:0004497	monooxygenase activity	4/2228	106/18639	0.0377358490566038	0.315690525388706	0.999191510088142	1
GO:0046873	metal ion transmembrane transporter activity	34/2228	450/18639	0.0755555555555556	0.632082585278276	0.999202122716145	1
GO:0003823	antigen binding	9/2228	174/18639	0.0517241379310345	0.432713737386244	0.999297599244986	1
GO:0004252	serine-type endopeptidase activity	9/2228	176/18639	0.0511363636363636	0.427796535825037	0.999406390498928	1
GO:0005267	potassium channel activity	5/2228	124/18639	0.0403225806451613	0.337330601725835	0.999442583964777	1
GO:0019199	transmembrane receptor protein kinase activity	2/2228	78/18639	0.0256410256410256	0.214507664687198	0.999445408578331	1
GO:0004222	metalloendopeptidase activity	4/2228	110/18639	0.0363636363636364	0.304210869920026	0.999462230248524	1
GO:0046906	tetrapyrrole binding	7/2228	152/18639	0.0460526315789474	0.385267055655296	0.999486741188138	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	1/2228	60/18639	0.0166666666666667	0.139429982046679	0.999524517637584	1
GO:0022843	voltage-gated monoatomic cation channel activity	6/2228	143/18639	0.041958041958042	0.351012542215415	0.999659563066997	1
GO:0008201	heparin binding	8/2228	172/18639	0.0465116279069767	0.389106926641894	0.999723152642652	1
GO:0005179	hormone activity	5/2228	132/18639	0.0378787878787879	0.316886322833361	0.999746401316498	1
GO:0004866	endopeptidase inhibitor activity	7/2228	161/18639	0.0434782608695652	0.363730387947857	0.999774559767491	1
GO:0003779	actin binding	31/2228	443/18639	0.0699774266365688	0.585417080376574	0.999811361365298	1
GO:0003777	microtubule motor activity	1/2228	68/18639	0.0147058823529412	0.123026454747069	0.999828911400277	1
GO:0008528	G protein-coupled peptide receptor activity	4/2228	122/18639	0.0327868852459016	0.274288489272155	0.99984495691145	1
GO:0005539	glycosaminoglycan binding	13/2228	242/18639	0.0537190082644628	0.449402421472766	0.999847560156567	1
GO:0030414	peptidase inhibitor activity	7/2228	169/18639	0.0414201183431953	0.346512381417781	0.999893092966627	1
GO:0001664	G protein-coupled receptor binding	17/2228	297/18639	0.0572390572390572	0.478850443392634	0.999911372862272	1
GO:0001653	peptide receptor activity	4/2228	128/18639	0.03125	0.261431216337522	0.999917605351002	1
GO:0004867	serine-type endopeptidase inhibitor activity	2/2228	95/18639	0.0210526315789474	0.176122082585278	0.999924359066646	1
GO:0033293	monocarboxylic acid binding	1/2228	79/18639	0.0126582278481013	0.105896188896212	0.999958071719386	1
GO:0005125	cytokine activity	10/2228	234/18639	0.0427350427350427	0.357512774478663	0.99998863111242	1
GO:0005261	monoatomic cation channel activity	18/2228	341/18639	0.0527859237536657	0.441596424077457	0.999992565047439	1
GO:0005216	monoatomic ion channel activity	27/2228	448/18639	0.0602678571428571	0.504188774365222	0.999992867247169	1
GO:0022836	gated channel activity	15/2228	318/18639	0.0471698113207547	0.394613156735883	0.999997756080312	1
GO:0005549	odorant binding	1/2228	111/18639	0.00900900900900901	0.0753675578630695	0.999999302271256	1
GO:0099094	ligand-gated monoatomic cation channel activity	2/2228	136/18639	0.0147058823529412	0.123026454747069	0.999999444951974	1
GO:0008083	growth factor activity	3/2228	162/18639	0.0185185185185185	0.154922202274087	0.999999730582468	1
GO:0015276	ligand-gated monoatomic ion channel activity	3/2228	186/18639	0.0161290322580645	0.134932240690334	0.999999983904291	1
GO:0022834	ligand-gated channel activity	3/2228	188/18639	0.0159574468085106	0.133496791321288	0.999999987294394	1
GO:0045182	translation regulator activity	10/2228	356/18639	0.0280898876404494	0.234994351764065	0.999999999931763	1
GO:0030371	translation repressor activity	5/2228	329/18639	0.0151975683890578	0.12713980125837	0.999999999999916	1
GO:0004984	olfactory receptor activity	4/2228	419/18639	0.00954653937947494	0.0798644288572861	1	1