ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	58/1890	175/18639	0.331428571428571	3.26851700680272	7.95125886649049e-17	9.32682665039334e-14
GO:0003712	transcription coregulator activity	96/1890	495/18639	0.193939393939394	1.91261183261183	2.76880667209842e-10	1.62390511318572e-07
GO:0019787	ubiquitin-like protein transferase activity	90/1890	479/18639	0.187891440501044	1.85296749179839	5.15962891150476e-09	2.01741490439836e-06
GO:0061659	ubiquitin-like protein ligase activity	73/1890	372/18639	0.196236559139785	1.93526625704045	2.31219132136198e-08	6.78050104989402e-06
GO:0016755	aminoacyltransferase activity	90/1890	496/18639	0.181451612903226	1.78945852534562	2.90932854035369e-08	6.82528475566976e-06
GO:0004842	ubiquitin-protein transferase activity	83/1890	449/18639	0.184855233853007	1.82302471099798	4.32807149803271e-08	8.46137977865395e-06
GO:0061630	ubiquitin protein ligase activity	68/1890	353/18639	0.192634560906516	1.8997436935114	1.45341206439358e-07	2.43550335933381e-05
GO:0044389	ubiquitin-like protein ligase binding	63/1890	322/18639	0.195652173913043	1.92950310559006	2.33444600369547e-07	3.38756842379174e-05
GO:0031625	ubiquitin protein ligase binding	60/1890	302/18639	0.198675496688742	1.9593188268685	2.59915735840799e-07	3.38756842379174e-05
GO:0003725	double-stranded RNA binding	23/1890	75/18639	0.306666666666667	3.02431746031746	7.75905025957913e-07	9.10136595448632e-05
GO:0051087	protein-folding chaperone binding	33/1890	134/18639	0.246268656716418	2.42867803837953	1.05156987137099e-06	0.000112135587192561
GO:0140297	DNA-binding transcription factor binding	81/1890	488/18639	0.165983606557377	1.63691451990632	5.60260507453576e-06	0.000547654646035871
GO:0043021	ribonucleoprotein complex binding	38/1890	177/18639	0.214689265536723	2.11724509012645	6.08930134048293e-06	0.000549442344029729
GO:0003713	transcription coactivator activity	49/1890	256/18639	0.19140625	1.88763020833333	9.26127190002167e-06	0.00077596228133753
GO:0140693	molecular condensate scaffold activity	16/1890	48/18639	0.333333333333333	3.28730158730159	1.122322603985e-05	0.000856807199600664
GO:0019207	kinase regulator activity	53/1890	287/18639	0.184668989547038	1.82118798739008	1.18924630480845e-05	0.000856807199600664
GO:0106310	protein serine kinase activity	63/1890	361/18639	0.174515235457064	1.72105263157895	1.24174956463864e-05	0.000856807199600664
GO:0008135	translation factor activity, RNA binding	22/1890	83/18639	0.265060240963855	2.61399885255307	1.85239001651023e-05	0.00120714082742583
GO:0180051	translation factor activity	22/1890	84/18639	0.261904761904762	2.5828798185941	2.27196186354151e-05	0.00140263750838642
GO:0004674	protein serine/threonine kinase activity	71/1890	433/18639	0.163972286374134	1.61707907181348	3.1368753258896e-05	0.00183977737863425
GO:0016922	nuclear receptor binding	30/1890	137/18639	0.218978102189781	2.15954118873827	3.76415887880431e-05	0.00210255160230355
GO:0051019	mitogen-activated protein kinase binding	11/1890	28/18639	0.392857142857143	3.87431972789116	4.73095036197266e-05	0.00252245671572452
GO:0031593	polyubiquitin modification-dependent protein binding	17/1890	59/18639	0.288135593220339	2.84156577885391	5.12740162362098e-05	0.0026149748280467
GO:0032182	ubiquitin-like protein binding	27/1890	120/18639	0.225	2.21892857142857	5.49504450130714e-05	0.00268570300001386
GO:0019783	ubiquitin-like protein peptidase activity	28/1890	127/18639	0.220472440944882	2.1742782152231	5.92777000690937e-05	0.00278130968724188
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	10/1890	25/18639	0.4	3.94476190476191	8.75978536354181e-05	0.00395201085824405
GO:0003743	translation initiation factor activity	15/1890	51/18639	0.294117647058824	2.90056022408964	0.000108217400712869	0.00470144485319243
GO:0045296	cadherin binding	56/1890	334/18639	0.167664670658683	1.65349301397206	0.000113475182859613	0.00475379962479737
GO:0140030	modification-dependent protein binding	34/1890	173/18639	0.196531791907514	1.93817781447839	0.000120248940309424	0.00486386230975706
GO:0061650	ubiquitin-like protein conjugating enzyme activity	13/1890	41/18639	0.317073170731707	3.12694541231127	0.000132685914027359	0.00518801923846975
GO:0035402	histone H3T11 kinase activity	44/1890	247/18639	0.178137651821862	1.75677655677656	0.000149509189468708	0.00547410335392622
GO:0042393	histone binding	44/1890	247/18639	0.178137651821862	1.75677655677656	0.000149509189468708	0.00547410335392622
GO:0003714	transcription corepressor activity	38/1890	204/18639	0.186274509803922	1.83702147525677	0.000160983895787691	0.00547410335392622
GO:0019843	rRNA binding	17/1890	65/18639	0.261538461538462	2.5792673992674	0.000191551023351821	0.00547410335392622
GO:0022884	macromolecule transmembrane transporter activity	11/1890	32/18639	0.34375	3.39002976190476	0.000193923280817431	0.00547410335392622
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	43/1890	243/18639	0.176954732510288	1.74511071918479	0.000205608750860744	0.00547410335392622
GO:0004676	3-phosphoinositide-dependent protein kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:0004711	ribosomal protein S6 kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:0035175	histone H3S10 kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:0035979	histone H2AXS139 kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:0044022	histone H3S28 kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:0044023	histone H4S1 kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:0044024	histone H2AS1 kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:0044025	histone H2BS14 kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:0072354	histone H3T3 kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:0072371	histone H2AS121 kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:0072518	Rho-dependent protein serine/threonine kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:0140823	histone H2BS36 kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:0140855	histone H3S57 kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:0140995	histone H2A kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:0140997	histone H4 kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:0140998	histone H2B kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:1990244	histone H2AT120 kinase activity	43/1890	245/18639	0.175510204081633	1.73086491739553	0.000247338003203827	0.00547410335392622
GO:0004677	DNA-dependent protein kinase activity	43/1890	246/18639	0.17479674796748	1.72382888114595	0.000270931437937594	0.00577822866728722
GO:0140857	histone H3T45 kinase activity	43/1890	246/18639	0.17479674796748	1.72382888114595	0.000270931437937594	0.00577822866728722
GO:0035403	histone H3T6 kinase activity	43/1890	247/18639	0.174089068825911	1.71684981684982	0.000296525343252113	0.00621114692204871
GO:0070990	snRNP binding	6/1890	11/18639	0.545454545454545	5.37922077922078	0.00031749230630106	0.00653365746124813
GO:0004679	AMP-activated protein kinase activity	43/1890	248/18639	0.173387096774194	1.70992703533026	0.000324266046359213	0.00655800124791995
GO:0048027	mRNA 5'-UTR binding	9/1890	24/18639	0.375	3.69821428571429	0.000352723731772279	0.00701262605709971
GO:0043130	ubiquitin binding	22/1890	100/18639	0.22	2.16961904761905	0.000363395008480304	0.00704736843648008
GO:0140996	histone H3 kinase activity	57/1890	357/18639	0.159663865546218	1.57458983593437	0.000366487190643892	0.00704736843648008
GO:0042605	peptide antigen binding	13/1890	45/18639	0.288888888888889	2.84899470899471	0.000373763575999217	0.00707136572011421
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	19/1890	82/18639	0.231707317073171	2.28507549361208	0.00045036056218099	0.00831683620113894
GO:0035173	histone kinase activity	57/1890	360/18639	0.158333333333333	1.56146825396825	0.000454058658156958	0.00831683620113894
GO:0101005	deubiquitinase activity	24/1890	115/18639	0.208695652173913	2.05813664596273	0.000460864751128756	0.00831683620113894
GO:0003727	single-stranded RNA binding	20/1890	89/18639	0.224719101123595	2.21615837346174	0.000493885550951205	0.00865703390936852
GO:0035925	mRNA 3'-UTR AU-rich region binding	10/1890	30/18639	0.333333333333333	3.28730158730159	0.00050149651359585	0.00865703390936852
GO:0008139	nuclear localization sequence binding	9/1890	25/18639	0.36	3.55028571428571	0.000501857038224262	0.00865703390936852
GO:0141003	histone H2AX kinase activity	56/1890	354/18639	0.15819209039548	1.56007532956686	0.000518335661148648	0.00881170623952702
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	19/1890	83/18639	0.228915662650602	2.25754446356856	0.000529410364607484	0.0088714051097797
GO:0140318	protein transporter activity	12/1890	41/18639	0.292682926829268	2.88641114982578	0.000546528781484214	0.00902927127719695
GO:0031072	heat shock protein binding	26/1890	131/18639	0.198473282442748	1.95732460923301	0.000616723136608873	0.0100474477672529
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	13/1890	48/18639	0.270833333333333	2.67093253968254	0.000740098859956123	0.0118922734620347
GO:0008375	acetylglucosaminyltransferase activity	12/1890	43/18639	0.27906976744186	2.75215946843854	0.00087661795028814	0.0138955791309188
GO:0003924	GTPase activity	52/1890	331/18639	0.157099697885196	1.54930225866782	0.000944043885864776	0.0146550821304437
GO:0004535	poly(A)-specific ribonuclease activity	6/1890	13/18639	0.461538461538462	4.55164835164835	0.0009857759816246	0.0146550821304437
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	25/1890	128/18639	0.1953125	1.92615327380952	0.000990693472446896	0.0146550821304437
GO:0033192	calmodulin-dependent protein phosphatase activity	18/1890	81/18639	0.222222222222222	2.19153439153439	0.00106196247322056	0.0146550821304437
GO:0140791	histone H2AXS140 phosphatase activity	18/1890	81/18639	0.222222222222222	2.19153439153439	0.00106196247322056	0.0146550821304437
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	18/1890	81/18639	0.222222222222222	2.19153439153439	0.00106196247322056	0.0146550821304437
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	18/1890	81/18639	0.222222222222222	2.19153439153439	0.00106196247322056	0.0146550821304437
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	18/1890	81/18639	0.222222222222222	2.19153439153439	0.00106196247322056	0.0146550821304437
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	18/1890	81/18639	0.222222222222222	2.19153439153439	0.00106196247322056	0.0146550821304437
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	18/1890	81/18639	0.222222222222222	2.19153439153439	0.00106196247322056	0.0146550821304437
GO:1990439	MAP kinase serine/threonine phosphatase activity	18/1890	81/18639	0.222222222222222	2.19153439153439	0.00106196247322056	0.0146550821304437
GO:0004843	cysteine-type deubiquitinase activity	22/1890	108/18639	0.203703703703704	2.00890652557319	0.00109384492740518	0.0148747271859226
GO:0019887	protein kinase regulator activity	42/1890	255/18639	0.164705882352941	1.6243137254902	0.00110324063527303	0.0148747271859226
GO:0044183	protein folding chaperone	17/1890	75/18639	0.226666666666667	2.23536507936508	0.00114540909426922	0.0152677825861113
GO:0033549	MAP kinase phosphatase activity	18/1890	82/18639	0.219512195121951	2.16480836236934	0.00123397551070044	0.0162635199331642
GO:0141052	histone H3 demethylase activity	9/1890	28/18639	0.321428571428571	3.16989795918367	0.00128202145858503	0.0167090130102248
GO:0005048	signal sequence binding	13/1890	51/18639	0.254901960784314	2.51381886087768	0.00136993969512674	0.0176586732130073
GO:0003724	RNA helicase activity	17/1890	77/18639	0.220779220779221	2.17730364873222	0.00155842217961824	0.0198698827901326
GO:0061980	regulatory RNA binding	14/1890	58/18639	0.241379310344828	2.38045977011494	0.00160929155987191	0.0202978387067715
GO:0017018	myosin phosphatase activity	18/1890	84/18639	0.214285714285714	2.11326530612245	0.00164969844109557	0.0203694344358432
GO:0051117	ATPase binding	18/1890	84/18639	0.214285714285714	2.11326530612245	0.00164969844109557	0.0203694344358432
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	53/1890	349/18639	0.151862464183381	1.49765315868468	0.00183535721546436	0.0224257709764552
GO:0008186	ATP-dependent activity, acting on RNA	17/1890	79/18639	0.215189873417722	2.12218203737191	0.00209031570492797	0.0252777352771186
GO:0008234	cysteine-type peptidase activity	32/1890	187/18639	0.171122994652406	1.68759867583397	0.00219719628089952	0.02611956495423
GO:0032452	histone demethylase activity	9/1890	30/18639	0.3	2.95857142857143	0.00220446456135445	0.02611956495423
GO:0015631	tubulin binding	57/1890	385/18639	0.148051948051948	1.46007421150278	0.00228163640283748	0.0265639681479609
GO:0042277	peptide binding	40/1890	249/18639	0.160642570281124	1.58424172882004	0.00228726409458146	0.0265639681479609
GO:0031386	protein tag activity	6/1890	15/18639	0.4	3.94476190476191	0.0024054043578086	0.0273935855505776
GO:0141047	molecular tag activity	6/1890	15/18639	0.4	3.94476190476191	0.0024054043578086	0.0273935855505776
GO:0005525	GTP binding	56/1890	378/18639	0.148148148148148	1.46102292768959	0.00244310693542819	0.027547891265509
GO:0035198	miRNA binding	11/1890	42/18639	0.261904761904762	2.5828798185941	0.002489408758861	0.027547891265509
GO:0048487	beta-tubulin binding	11/1890	42/18639	0.261904761904762	2.5828798185941	0.002489408758861	0.027547891265509
GO:0043024	ribosomal small subunit binding	7/1890	20/18639	0.35	3.45166666666667	0.00256945428844823	0.0281679428070072
GO:0140457	protein demethylase activity	9/1890	31/18639	0.290322580645161	2.863133640553	0.00283071394588038	0.0307446986899786
GO:0001222	transcription corepressor binding	12/1890	49/18639	0.244897959183673	2.41516034985423	0.00297763182002781	0.0317523829535693
GO:0060590	ATPase regulator activity	12/1890	49/18639	0.244897959183673	2.41516034985423	0.00297763182002781	0.0317523829535693
GO:0140767	enzyme-substrate adaptor activity	25/1890	139/18639	0.179856115107914	1.77372387804042	0.00323843132349864	0.0340623132973541
GO:0004722	protein serine/threonine phosphatase activity	20/1890	103/18639	0.194174757281553	1.91493296347665	0.00325232658934668	0.0340623132973541
GO:0001217	DNA-binding transcription repressor activity	43/1890	278/18639	0.154676258992806	1.52540253511477	0.00333086857815905	0.0345761844440758
GO:0035613	RNA stem-loop binding	7/1890	21/18639	0.333333333333333	3.28730158730159	0.00352069313426427	0.0359175037175712
GO:0034450	ubiquitin-ubiquitin ligase activity	6/1890	16/18639	0.375	3.69821428571429	0.00352132389387953	0.0359175037175712
GO:0140104	molecular carrier activity	39/1890	249/18639	0.156626506024096	1.54463568559954	0.00403193232973256	0.0407711777825543
GO:0008320	protein transmembrane transporter activity	8/1890	27/18639	0.296296296296296	2.92204585537919	0.00418903796252877	0.0419977908550962
GO:0030544	Hsp70 protein binding	12/1890	51/18639	0.235294117647059	2.32044817927171	0.00423799530069662	0.0421285465060775
GO:0071889	14-3-3 protein binding	9/1890	33/18639	0.272727272727273	2.68961038961039	0.00449886340048346	0.0442519912828728
GO:0140597	protein carrier chaperone	31/1890	188/18639	0.164893617021277	1.62616514690983	0.00452705793175169	0.0442519912828728
GO:0035259	nuclear glucocorticoid receptor binding	5/1890	12/18639	0.416666666666667	4.10912698412698	0.00458528584962397	0.0444507462942886
GO:0140517	protein-RNA adaptor activity	7/1890	22/18639	0.318181818181818	3.13787878787879	0.00471773765669549	0.0453598874697033
GO:0044325	transmembrane transporter binding	24/1890	136/18639	0.176470588235294	1.74033613445378	0.00495450078601132	0.04711177292759
GO:0008429	phosphatidylethanolamine binding	6/1890	17/18639	0.352941176470588	3.48067226890756	0.00498027267094728	0.04711177292759
GO:0046332	SMAD binding	16/1890	79/18639	0.20253164556962	1.99734779987945	0.00524255635500844	0.0485393249465069
GO:0019001	guanyl nucleotide binding	57/1890	400/18639	0.1425	1.40532142857143	0.00525532333180424	0.0485393249465069
GO:0032561	guanyl ribonucleotide binding	57/1890	400/18639	0.1425	1.40532142857143	0.00525532333180424	0.0485393249465069
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	22/1890	122/18639	0.180327868852459	1.7783762685402	0.00534440816507218	0.0489764904502317
GO:0001221	transcription coregulator binding	21/1890	115/18639	0.182608695652174	1.80086956521739	0.00552128084578835	0.0495530540380407
GO:0004532	RNA exonuclease activity	10/1890	40/18639	0.25	2.46547619047619	0.00553405803834896	0.0495530540380407
GO:0032451	demethylase activity	10/1890	40/18639	0.25	2.46547619047619	0.00553405803834896	0.0495530540380407
GO:0008137	NADH dehydrogenase (ubiquinone) activity	10/1890	41/18639	0.24390243902439	2.40534262485482	0.00666777473324456	0.0588067651285403
GO:0042287	MHC protein binding	10/1890	41/18639	0.24390243902439	2.40534262485482	0.00666777473324456	0.0588067651285403
GO:0000175	3'-5'-RNA exonuclease activity	9/1890	35/18639	0.257142857142857	2.53591836734694	0.00684631460831045	0.0590248462653323
GO:0061631	ubiquitin conjugating enzyme activity	9/1890	35/18639	0.257142857142857	2.53591836734694	0.00684631460831045	0.0590248462653323
GO:0003925	G protein activity	12/1890	54/18639	0.222222222222222	2.19153439153439	0.0068937799985938	0.0590248462653323
GO:0017069	snRNA binding	12/1890	54/18639	0.222222222222222	2.19153439153439	0.0068937799985938	0.0590248462653323
GO:0019209	kinase activator activity	25/1890	148/18639	0.168918918918919	1.66586229086229	0.0074252114708072	0.0631142975018612
GO:0019003	GDP binding	15/1890	75/18639	0.2	1.97238095238095	0.0075988058153382	0.0641251742546166
GO:0140713	histone chaperone activity	27/1890	164/18639	0.164634146341463	1.623606271777	0.00785076425655023	0.0657781890923815
GO:0008187	poly-pyrimidine tract binding	8/1890	30/18639	0.266666666666667	2.62984126984127	0.00839674659995339	0.0698537855442931
GO:0043022	ribosome binding	20/1890	112/18639	0.178571428571429	1.76105442176871	0.00854935738372242	0.0706225085289183
GO:1990380	K48-linked deubiquitinase activity	6/1890	19/18639	0.315789473684211	3.11428571428571	0.00915001758418833	0.0749704492387189
GO:0015399	primary active transmembrane transporter activity	27/1890	166/18639	0.162650602409639	1.60404475043029	0.00920353341037982	0.0749704492387189
GO:0140789	histone phosphatase activity	23/1890	136/18639	0.169117647058824	1.66782212885154	0.00980542811880235	0.0793225322990011
GO:0051082	unfolded protein binding	21/1890	121/18639	0.173553719008264	1.71157024793388	0.00991071978196273	0.0796251664674129
GO:0035591	signaling adaptor activity	22/1890	129/18639	0.170542635658915	1.68187523071244	0.0103291864926262	0.0824226922166707
GO:0019888	protein phosphatase regulator activity	19/1890	107/18639	0.177570093457944	1.75117935024477	0.0108212696540981	0.0857658736774123
GO:0003954	NADH dehydrogenase activity	10/1890	44/18639	0.227272727272727	2.24134199134199	0.0111656466010861	0.0879013655239862
GO:0017124	SH3 domain binding	20/1890	115/18639	0.173913043478261	1.71511387163561	0.0113926431902754	0.0890904697479539
GO:0042288	MHC class I protein binding	6/1890	20/18639	0.3	2.95857142857143	0.0119702589966484	0.0919338962191199
GO:0061608	nuclear import signal receptor activity	6/1890	20/18639	0.3	2.95857142857143	0.0119702589966484	0.0919338962191199
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	9/1890	38/18639	0.236842105263158	2.33571428571429	0.0119913777677113	0.0919338962191199
GO:0016887	ATP hydrolysis activity	57/1890	417/18639	0.136690647482014	1.34803014731072	0.0121373755411331	0.0924489708425267
GO:0070717	poly-purine tract binding	8/1890	32/18639	0.25	2.46547619047619	0.0125805221479338	0.0952061450292023
GO:0008017	microtubule binding	40/1890	276/18639	0.144927536231884	1.42926155969634	0.0132511557463206	0.0967143927431895
GO:0005528	FK506 binding	4/1890	10/18639	0.4	3.94476190476191	0.0134047452681915	0.0967143927431895
GO:0008140	cAMP response element binding protein binding	4/1890	10/18639	0.4	3.94476190476191	0.0134047452681915	0.0967143927431895
GO:0043422	protein kinase B binding	4/1890	10/18639	0.4	3.94476190476191	0.0134047452681915	0.0967143927431895
GO:0051864	histone H3K36 demethylase activity	4/1890	10/18639	0.4	3.94476190476191	0.0134047452681915	0.0967143927431895
GO:0000774	adenyl-nucleotide exchange factor activity	5/1890	15/18639	0.333333333333333	3.28730158730159	0.0134308077741401	0.0967143927431895
GO:0061578	K63-linked deubiquitinase activity	5/1890	15/18639	0.333333333333333	3.28730158730159	0.0134308077741401	0.0967143927431895
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	39/1890	268/18639	0.145522388059701	1.43512793176972	0.0134394254195566	0.0967143927431895
GO:0019208	phosphatase regulator activity	20/1890	117/18639	0.170940170940171	1.68579568579569	0.0136747190354697	0.0978075940768655
GO:0043539	protein serine/threonine kinase activator activity	14/1890	73/18639	0.191780821917808	1.89132420091324	0.0139771953589101	0.0992634342731552
GO:0036002	pre-mRNA binding	12/1890	59/18639	0.203389830508475	2.00581113801453	0.0140475107326034	0.0992634342731552
GO:0022853	active monoatomic ion transmembrane transporter activity	20/1890	118/18639	0.169491525423729	1.67150928167877	0.0149437936370392	0.10496449063621
GO:0009931	calcium-dependent protein serine/threonine kinase activity	6/1890	21/18639	0.285714285714286	2.81768707482993	0.015350085341602	0.107176488724399
GO:0001671	ATPase activator activity	7/1890	27/18639	0.259259259259259	2.55679012345679	0.0156824827148179	0.108209130732243
GO:0008266	poly(U) RNA binding	7/1890	27/18639	0.259259259259259	2.55679012345679	0.0156824827148179	0.108209130732243
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/1890	16/18639	0.3125	3.08184523809524	0.0179351186288041	0.121606324575648
GO:0004708	MAP kinase kinase activity	5/1890	16/18639	0.3125	3.08184523809524	0.0179351186288041	0.121606324575648
GO:0070411	I-SMAD binding	5/1890	16/18639	0.3125	3.08184523809524	0.0179351186288041	0.121606324575648
GO:0046625	sphingolipid binding	7/1890	28/18639	0.25	2.46547619047619	0.0191260287650551	0.128199038522341
GO:0046966	nuclear thyroid hormone receptor binding	7/1890	28/18639	0.25	2.46547619047619	0.0191260287650551	0.128199038522341
GO:0140035	ubiquitin-like protein reader activity	6/1890	22/18639	0.272727272727273	2.68961038961039	0.019337215723442	0.128552556073133
GO:0019107	myristoyltransferase activity	4/1890	11/18639	0.363636363636364	3.58614718614719	0.0193979560314957	0.128552556073133
GO:0061775	cohesin loader activity	24/1890	153/18639	0.156862745098039	1.54696545284781	0.0203783009759681	0.134290713734891
GO:0043015	gamma-tubulin binding	8/1890	35/18639	0.228571428571429	2.25414965986395	0.0214565073834714	0.140606051177721
GO:0043175	RNA polymerase core enzyme binding	9/1890	42/18639	0.214285714285714	2.11326530612245	0.0227428645411433	0.148207667259784
GO:0140103	catalytic activity, acting on a glycoprotein	6/1890	23/18639	0.260869565217391	2.57267080745342	0.023974869351041	0.155373048335752
GO:0051219	phosphoprotein binding	16/1890	93/18639	0.172043010752688	1.69667178699437	0.0241796670661258	0.155839282794316
GO:0016409	palmitoyltransferase activity	8/1890	36/18639	0.222222222222222	2.19153439153439	0.0252085675177934	0.161582785237004
GO:0000287	magnesium ion binding	33/1890	230/18639	0.143478260869565	1.41496894409938	0.0259330266870807	0.165323045130139
GO:0005095	GTPase inhibitor activity	4/1890	12/18639	0.333333333333333	3.28730158730159	0.0268042911224316	0.16724166748198
GO:0005527	macrolide binding	4/1890	12/18639	0.333333333333333	3.28730158730159	0.0268042911224316	0.16724166748198
GO:0035014	phosphatidylinositol 3-kinase regulator activity	4/1890	12/18639	0.333333333333333	3.28730158730159	0.0268042911224316	0.16724166748198
GO:1990817	poly(A) RNA polymerase activity	4/1890	12/18639	0.333333333333333	3.28730158730159	0.0268042911224316	0.16724166748198
GO:0031624	ubiquitin conjugating enzyme binding	7/1890	30/18639	0.233333333333333	2.30111111111111	0.0275296384533131	0.169959294240717
GO:0070566	adenylyltransferase activity	7/1890	30/18639	0.233333333333333	2.30111111111111	0.0275296384533131	0.169959294240717
GO:0140658	ATP-dependent chromatin remodeler activity	24/1890	158/18639	0.151898734177215	1.49801084990958	0.0288636719391935	0.177262236568974
GO:0060229	lipase activator activity	6/1890	24/18639	0.25	2.46547619047619	0.0293010405998793	0.178833999701356
GO:0008308	voltage-gated monoatomic anion channel activity	5/1890	18/18639	0.277777777777778	2.73941798941799	0.0296771858488842	0.178833999701356
GO:0050811	GABA receptor binding	5/1890	18/18639	0.277777777777778	2.73941798941799	0.0296771858488842	0.178833999701356
GO:0031267	small GTPase binding	39/1890	283/18639	0.137809187279152	1.35906108026249	0.0297294372905068	0.178833999701356
GO:0043014	alpha-tubulin binding	9/1890	44/18639	0.204545454545455	2.01720779220779	0.0301375926454658	0.180364266189446
GO:0004721	phosphoprotein phosphatase activity	26/1890	175/18639	0.148571428571429	1.46519727891156	0.0303386928906673	0.1806461256891
GO:0000510	H3-H4 histone complex chaperone activity	23/1890	151/18639	0.152317880794702	1.50214443393251	0.0310019694647144	0.180921941204527
GO:0140584	chromatin extrusion motor activity	23/1890	151/18639	0.152317880794702	1.50214443393251	0.0310019694647144	0.180921941204527
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	23/1890	151/18639	0.152317880794702	1.50214443393251	0.0310019694647144	0.180921941204527
GO:0140849	ATP-dependent H2AZ histone chaperone activity	23/1890	151/18639	0.152317880794702	1.50214443393251	0.0310019694647144	0.180921941204527
GO:0015616	DNA translocase activity	23/1890	152/18639	0.151315789473684	1.4922619047619	0.0331519507192667	0.190897498575623
GO:0140674	ATP-dependent histone chaperone activity	23/1890	152/18639	0.151315789473684	1.4922619047619	0.0331519507192667	0.190897498575623
GO:0070063	RNA polymerase binding	11/1890	59/18639	0.186440677966102	1.83866020984665	0.0332139790436	0.190897498575623
GO:0016779	nucleotidyltransferase activity	21/1890	136/18639	0.154411764705882	1.52279411764706	0.0333623079352111	0.190897498575623
GO:0017056	structural constituent of nuclear pore	6/1890	25/18639	0.24	2.36685714285714	0.0353479244313777	0.199295720334188
GO:0019706	protein-cysteine S-palmitoyltransferase activity	6/1890	25/18639	0.24	2.36685714285714	0.0353479244313777	0.199295720334188
GO:0019707	protein-cysteine S-acyltransferase activity	6/1890	25/18639	0.24	2.36685714285714	0.0353479244313777	0.199295720334188
GO:0097157	pre-mRNA intronic binding	4/1890	13/18639	0.307692307692308	3.03443223443223	0.0356795407247908	0.199295720334188
GO:0140852	histone ubiquitin ligase activity	4/1890	13/18639	0.307692307692308	3.03443223443223	0.0356795407247908	0.199295720334188
GO:0019210	kinase inhibitor activity	15/1890	90/18639	0.166666666666667	1.64365079365079	0.0366039822204932	0.203490384571747
GO:0097001	ceramide binding	5/1890	19/18639	0.263157894736842	2.5952380952381	0.0370083173719898	0.203806367499268
GO:0140036	ubiquitin-modified protein reader activity	5/1890	19/18639	0.263157894736842	2.5952380952381	0.0370083173719898	0.203806367499268
GO:0051059	NF-kappaB binding	7/1890	32/18639	0.21875	2.15729166666667	0.0381355597371099	0.208060518937814
GO:0140142	nucleocytoplasmic carrier activity	7/1890	32/18639	0.21875	2.15729166666667	0.0381355597371099	0.208060518937814
GO:0030695	GTPase regulator activity	62/1890	489/18639	0.12678936605317	1.25038465283864	0.0383303824907407	0.208155271581661
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	12/1890	68/18639	0.176470588235294	1.74033613445378	0.0394150707977821	0.212082009384396
GO:1990841	promoter-specific chromatin binding	12/1890	68/18639	0.176470588235294	1.74033613445378	0.0394150707977821	0.212082009384396
GO:0060589	nucleoside-triphosphatase regulator activity	62/1890	490/18639	0.126530612244898	1.24783284742468	0.0396901871604432	0.212587166845662
GO:0030295	protein kinase activator activity	21/1890	139/18639	0.151079136690647	1.48992805755396	0.0409931712960576	0.218522958223336
GO:0140034	methylation-dependent protein binding	13/1890	76/18639	0.171052631578947	1.68690476190476	0.0411709921290343	0.218522958223336
GO:0016791	phosphatase activity	37/1890	273/18639	0.135531135531136	1.33659515088087	0.0415733845071826	0.21966477489606
GO:0005160	transforming growth factor beta receptor binding	6/1890	26/18639	0.230769230769231	2.27582417582418	0.0421414915381904	0.221668024996849
GO:0140416	transcription regulator inhibitor activity	7/1890	33/18639	0.212121212121212	2.09191919191919	0.0443194961805693	0.232083790266999
GO:0016004	phospholipase activator activity	5/1890	20/18639	0.25	2.46547619047619	0.0453543368304371	0.236447276009345
GO:0030983	mismatched DNA binding	4/1890	14/18639	0.285714285714286	2.81768707482993	0.0460490876938952	0.239006990552828
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	6/1890	27/18639	0.222222222222222	2.19153439153439	0.0497012083448682	0.256826067790883
GO:0030332	cyclin binding	7/1890	34/18639	0.205882352941176	2.03039215686274	0.0511127269220488	0.26296152929633
GO:0042826	histone deacetylase binding	19/1890	127/18639	0.149606299212598	1.47540307461567	0.0543365355084845	0.277918054279129
GO:0003689	DNA clamp loader activity	23/1890	160/18639	0.14375	1.41764880952381	0.0545518139320828	0.277918054279129
GO:0140312	cargo adaptor activity	5/1890	21/18639	0.238095238095238	2.34807256235828	0.054730665420698	0.277918054279129
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/1890	15/18639	0.266666666666667	2.62984126984127	0.0579102803919879	0.283669980384545
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/1890	15/18639	0.266666666666667	2.62984126984127	0.0579102803919879	0.283669980384545
GO:0042809	nuclear vitamin D receptor binding	4/1890	15/18639	0.266666666666667	2.62984126984127	0.0579102803919879	0.283669980384545
GO:0050700	CARD domain binding	4/1890	15/18639	0.266666666666667	2.62984126984127	0.0579102803919879	0.283669980384545
GO:0055105	ubiquitin-protein transferase inhibitor activity	4/1890	15/18639	0.266666666666667	2.62984126984127	0.0579102803919879	0.283669980384545
GO:0031490	chromatin DNA binding	19/1890	128/18639	0.1484375	1.46387648809524	0.058000883597828	0.283669980384545
GO:0019789	SUMO transferase activity	6/1890	28/18639	0.214285714285714	2.11326530612245	0.0580398936848173	0.283669980384545
GO:0046875	ephrin receptor binding	6/1890	28/18639	0.214285714285714	2.11326530612245	0.0580398936848173	0.283669980384545
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	6/1890	28/18639	0.214285714285714	2.11326530612245	0.0580398936848173	0.283669980384545
GO:0005154	epidermal growth factor receptor binding	7/1890	35/18639	0.2	1.97238095238095	0.0585267818066931	0.283685599418392
GO:0140566	histone reader activity	7/1890	35/18639	0.2	1.97238095238095	0.0585267818066931	0.283685599418392
GO:0015932	nucleobase-containing compound transmembrane transporter activity	10/1890	57/18639	0.175438596491228	1.73015873015873	0.0588691180732202	0.284170681069495
GO:0004197	cysteine-type endopeptidase activity	14/1890	88/18639	0.159090909090909	1.56893939393939	0.059157189342276	0.284390914338073
GO:0004712	protein serine/threonine/tyrosine kinase activity	8/1890	43/18639	0.186046511627907	1.83477297895903	0.0646013395741667	0.309295393144888
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	10/1890	58/18639	0.172413793103448	1.70032840722496	0.0649583989848324	0.309351460259239
GO:0050321	tau-protein kinase activity	5/1890	22/18639	0.227272727272727	2.24134199134199	0.0651405035669498	0.309351460259239
GO:0004386	helicase activity	22/1890	155/18639	0.141935483870968	1.39975422427035	0.0660750132485583	0.312524155405479
GO:0044390	ubiquitin-like protein conjugating enzyme binding	7/1890	36/18639	0.194444444444444	1.91759259259259	0.0665691093936688	0.31359664786656
GO:0016417	S-acyltransferase activity	6/1890	29/18639	0.206896551724138	2.04039408866995	0.0671637015101968	0.315132087485844
GO:0035064	methylated histone binding	12/1890	74/18639	0.162162162162162	1.5992277992278	0.0681842023132398	0.318645694475818
GO:0042626	ATPase-coupled transmembrane transporter activity	15/1890	98/18639	0.153061224489796	1.50947521865889	0.0687905500146891	0.320203631615993
GO:0019902	phosphatase binding	26/1890	190/18639	0.136842105263158	1.34952380952381	0.0704010598258478	0.322448032914153
GO:0005521	lamin binding	4/1890	16/18639	0.25	2.46547619047619	0.0712353343130491	0.322448032914153
GO:0008142	oxysterol binding	4/1890	16/18639	0.25	2.46547619047619	0.0712353343130491	0.322448032914153
GO:0140328	floppase activity	4/1890	16/18639	0.25	2.46547619047619	0.0712353343130491	0.322448032914153
GO:0015279	store-operated calcium channel activity	3/1890	10/18639	0.3	2.95857142857143	0.0725714242875842	0.322448032914153
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/1890	10/18639	0.3	2.95857142857143	0.0725714242875842	0.322448032914153
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/1890	10/18639	0.3	2.95857142857143	0.0725714242875842	0.322448032914153
GO:0030957	Tat protein binding	3/1890	10/18639	0.3	2.95857142857143	0.0725714242875842	0.322448032914153
GO:0031996	thioesterase binding	3/1890	10/18639	0.3	2.95857142857143	0.0725714242875842	0.322448032914153
GO:0045322	unmethylated CpG binding	3/1890	10/18639	0.3	2.95857142857143	0.0725714242875842	0.322448032914153
GO:0070097	delta-catenin binding	3/1890	10/18639	0.3	2.95857142857143	0.0725714242875842	0.322448032914153
GO:1905394	retromer complex binding	3/1890	10/18639	0.3	2.95857142857143	0.0725714242875842	0.322448032914153
GO:0023023	MHC protein complex binding	7/1890	37/18639	0.189189189189189	1.86576576576577	0.0752430469685268	0.333056958845592
GO:0005080	protein kinase C binding	9/1890	52/18639	0.173076923076923	1.70686813186813	0.0759820071441493	0.335063512707095
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	5/1890	23/18639	0.217391304347826	2.14389233954451	0.0765754019602577	0.335160248132024
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	5/1890	23/18639	0.217391304347826	2.14389233954451	0.0765754019602577	0.335160248132024
GO:0015215	nucleotide transmembrane transporter activity	6/1890	30/18639	0.2	1.97238095238095	0.0770722172744177	0.336080709527479
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	10/1890	60/18639	0.166666666666667	1.64365079365079	0.0783079174693781	0.340204397005854
GO:0004860	protein kinase inhibitor activity	13/1890	84/18639	0.154761904761905	1.52624716553288	0.0802143313072923	0.346922136933656
GO:0140303	intramembrane lipid transporter activity	8/1890	45/18639	0.177777777777778	1.75322751322751	0.080445712912152	0.346922136933656
GO:0015026	coreceptor activity	10/1890	61/18639	0.163934426229508	1.61670569867291	0.0855735476530025	0.366720419883232
GO:0032183	SUMO binding	4/1890	17/18639	0.235294117647059	2.32044817927171	0.0859745229905276	0.366720419883232
GO:0051787	misfolded protein binding	4/1890	17/18639	0.235294117647059	2.32044817927171	0.0859745229905276	0.366720419883232
GO:0035035	histone acetyltransferase binding	5/1890	24/18639	0.208333333333333	2.05456349206349	0.0890160233708837	0.378318099326256
GO:0005085	guanyl-nucleotide exchange factor activity	30/1890	230/18639	0.130434782608696	1.28633540372671	0.090479865547628	0.37942643370099
GO:0140463	chromatin-protein adaptor activity	9/1890	54/18639	0.166666666666667	1.64365079365079	0.0918553311035709	0.37942643370099
GO:0005225	volume-sensitive anion channel activity	3/1890	11/18639	0.272727272727273	2.68961038961039	0.0925114748836174	0.37942643370099
GO:0008432	JUN kinase binding	3/1890	11/18639	0.272727272727273	2.68961038961039	0.0925114748836174	0.37942643370099
GO:0010854	adenylate cyclase regulator activity	3/1890	11/18639	0.272727272727273	2.68961038961039	0.0925114748836174	0.37942643370099
GO:0015173	aromatic amino acid transmembrane transporter activity	3/1890	11/18639	0.272727272727273	2.68961038961039	0.0925114748836174	0.37942643370099
GO:0019206	nucleoside kinase activity	3/1890	11/18639	0.272727272727273	2.68961038961039	0.0925114748836174	0.37942643370099
GO:0034713	type I transforming growth factor beta receptor binding	3/1890	11/18639	0.272727272727273	2.68961038961039	0.0925114748836174	0.37942643370099
GO:0140537	transcription regulator activator activity	3/1890	11/18639	0.272727272727273	2.68961038961039	0.0925114748836174	0.37942643370099
GO:1990948	ubiquitin ligase inhibitor activity	3/1890	11/18639	0.272727272727273	2.68961038961039	0.0925114748836174	0.37942643370099
GO:0097110	scaffold protein binding	11/1890	70/18639	0.157142857142857	1.54972789115646	0.093682563578475	0.382890756367774
GO:0016757	glycosyltransferase activity	34/1890	267/18639	0.127340823970037	1.25582307829499	0.0974450170183809	0.39688543389778
GO:0031369	translation initiation factor binding	6/1890	32/18639	0.1875	1.84910714285714	0.0992101379767327	0.40267644237615
GO:0003746	translation elongation factor activity	4/1890	18/18639	0.222222222222222	2.19153439153439	0.102059476459569	0.403201226268646
GO:0004706	JUN kinase kinase kinase activity	4/1890	18/18639	0.222222222222222	2.19153439153439	0.102059476459569	0.403201226268646
GO:0035615	clathrin adaptor activity	4/1890	18/18639	0.222222222222222	2.19153439153439	0.102059476459569	0.403201226268646
GO:0070628	proteasome binding	4/1890	18/18639	0.222222222222222	2.19153439153439	0.102059476459569	0.403201226268646
GO:1990381	ubiquitin-specific protease binding	4/1890	18/18639	0.222222222222222	2.19153439153439	0.102059476459569	0.403201226268646
GO:0004709	MAP kinase kinase kinase activity	5/1890	25/18639	0.2	1.97238095238095	0.10243304810576	0.403201226268646
GO:0015662	P-type ion transporter activity	5/1890	25/18639	0.2	1.97238095238095	0.10243304810576	0.403201226268646
GO:0042974	nuclear retinoic acid receptor binding	5/1890	25/18639	0.2	1.97238095238095	0.10243304810576	0.403201226268646
GO:0140358	P-type transmembrane transporter activity	5/1890	25/18639	0.2	1.97238095238095	0.10243304810576	0.403201226268646
GO:0003697	single-stranded DNA binding	17/1890	121/18639	0.140495867768595	1.38555686737505	0.104013636907248	0.408053498636127
GO:0030331	nuclear estrogen receptor binding	7/1890	40/18639	0.175	1.72583333333333	0.105027099939767	0.410655960764489
GO:0000049	tRNA binding	12/1890	80/18639	0.15	1.47928571428571	0.107987699123597	0.420829139774019
GO:0051020	GTPase binding	39/1890	315/18639	0.123809523809524	1.2209977324263	0.110457056180208	0.429026910262859
GO:0019956	chemokine binding	6/1890	33/18639	0.181818181818182	1.79307359307359	0.11140805837588	0.429873856825353
GO:0140311	protein sequestering activity	6/1890	33/18639	0.181818181818182	1.79307359307359	0.11140805837588	0.429873856825353
GO:0010853	cyclase activator activity	3/1890	12/18639	0.25	2.46547619047619	0.114413869470679	0.434328378281899
GO:0035197	siRNA binding	3/1890	12/18639	0.25	2.46547619047619	0.114413869470679	0.434328378281899
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/1890	12/18639	0.25	2.46547619047619	0.114413869470679	0.434328378281899
GO:0070410	co-SMAD binding	3/1890	12/18639	0.25	2.46547619047619	0.114413869470679	0.434328378281899
GO:1990459	transferrin receptor binding	3/1890	12/18639	0.25	2.46547619047619	0.114413869470679	0.434328378281899
GO:0004713	protein tyrosine kinase activity	19/1890	140/18639	0.135714285714286	1.33840136054422	0.115703362638067	0.437806594756297
GO:0008143	poly(A) binding	5/1890	26/18639	0.192307692307692	1.89652014652015	0.116788180621848	0.439078640607141
GO:0050681	nuclear androgen receptor binding	5/1890	26/18639	0.192307692307692	1.89652014652015	0.116788180621848	0.439078640607141
GO:0005346	purine ribonucleotide transmembrane transporter activity	4/1890	19/18639	0.210526315789474	2.07619047619048	0.119406452216256	0.447488078113957
GO:0042578	phosphoric ester hydrolase activity	44/1890	363/18639	0.121212121212121	1.1953823953824	0.121410875288148	0.453550817557316
GO:0009055	electron transfer activity	16/1890	116/18639	0.137931034482759	1.36026272577997	0.126298903268278	0.470313058837111
GO:0008408	3'-5' exonuclease activity	9/1890	58/18639	0.155172413793103	1.53029556650246	0.128954218287205	0.477980909089175
GO:0015605	organophosphate ester transmembrane transporter activity	8/1890	50/18639	0.16	1.57790476190476	0.129173016352317	0.477980909089175
GO:0004683	calcium/calmodulin-dependent protein kinase activity	5/1890	27/18639	0.185185185185185	1.82627865961199	0.132035219775707	0.483991602490327
GO:0023026	MHC class II protein complex binding	5/1890	27/18639	0.185185185185185	1.82627865961199	0.132035219775707	0.483991602490327
GO:0035255	ionotropic glutamate receptor binding	5/1890	27/18639	0.185185185185185	1.82627865961199	0.132035219775707	0.483991602490327
GO:0000339	RNA cap binding	4/1890	20/18639	0.2	1.97238095238095	0.137919481062711	0.49666895452388
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/1890	13/18639	0.230769230769231	2.27582417582418	0.138034168094446	0.49666895452388
GO:0031432	titin binding	3/1890	13/18639	0.230769230769231	2.27582417582418	0.138034168094446	0.49666895452388
GO:0140333	glycerophospholipid flippase activity	3/1890	13/18639	0.230769230769231	2.27582417582418	0.138034168094446	0.49666895452388
GO:0140666	annealing activity	3/1890	13/18639	0.230769230769231	2.27582417582418	0.138034168094446	0.49666895452388
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	3/1890	13/18639	0.230769230769231	2.27582417582418	0.138034168094446	0.49666895452388
GO:0004879	nuclear receptor activity	9/1890	59/18639	0.152542372881356	1.5043583535109	0.139307344212771	0.498193642565793
GO:0045309	protein phosphorylated amino acid binding	9/1890	59/18639	0.152542372881356	1.5043583535109	0.139307344212771	0.498193642565793
GO:0140098	catalytic activity, acting on RNA	46/1890	387/18639	0.118863049095607	1.17221606989049	0.143893807566059	0.513031721200569
GO:0002020	protease binding	18/1890	136/18639	0.132352941176471	1.30525210084034	0.145533284017838	0.517304673190679
GO:0030145	manganese ion binding	10/1890	68/18639	0.147058823529412	1.45028011204482	0.147330475378113	0.520538095236526
GO:0032934	sterol binding	10/1890	68/18639	0.147058823529412	1.45028011204482	0.147330475378113	0.520538095236526
GO:0051537	2 iron, 2 sulfur cluster binding	5/1890	28/18639	0.178571428571429	1.76105442176871	0.148121160230249	0.521760122973218
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	9/1890	60/18639	0.15	1.47928571428571	0.150071948932193	0.525475809246157
GO:0098531	ligand-modulated transcription factor activity	9/1890	60/18639	0.15	1.47928571428571	0.150071948932193	0.525475809246157
GO:0000993	RNA polymerase II complex binding	6/1890	36/18639	0.166666666666667	1.64365079365079	0.152217336944137	0.526698926948296
GO:0005484	SNAP receptor activity	6/1890	36/18639	0.166666666666667	1.64365079365079	0.152217336944137	0.526698926948296
GO:0045505	dynein intermediate chain binding	6/1890	36/18639	0.166666666666667	1.64365079365079	0.152217336944137	0.526698926948296
GO:0055106	ubiquitin-protein transferase regulator activity	6/1890	36/18639	0.166666666666667	1.64365079365079	0.152217336944137	0.526698926948296
GO:0001046	core promoter sequence-specific DNA binding	7/1890	44/18639	0.159090909090909	1.56893939393939	0.153095988930019	0.528181161808567
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	4/1890	21/18639	0.19047619047619	1.87845804988662	0.157493320037302	0.535991291899312
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	4/1890	21/18639	0.19047619047619	1.87845804988662	0.157493320037302	0.535991291899312
GO:0051010	microtubule plus-end binding	4/1890	21/18639	0.19047619047619	1.87845804988662	0.157493320037302	0.535991291899312
GO:0072542	protein phosphatase activator activity	4/1890	21/18639	0.19047619047619	1.87845804988662	0.157493320037302	0.535991291899312
GO:0002039	p53 binding	10/1890	69/18639	0.144927536231884	1.42926155969634	0.157644497617445	0.535991291899312
GO:0005161	platelet-derived growth factor receptor binding	3/1890	14/18639	0.214285714285714	2.11326530612245	0.163121008203687	0.543582223360582
GO:0005347	ATP transmembrane transporter activity	3/1890	14/18639	0.214285714285714	2.11326530612245	0.163121008203687	0.543582223360582
GO:0005545	1-phosphatidylinositol binding	3/1890	14/18639	0.214285714285714	2.11326530612245	0.163121008203687	0.543582223360582
GO:0008174	mRNA methyltransferase activity	3/1890	14/18639	0.214285714285714	2.11326530612245	0.163121008203687	0.543582223360582
GO:0042043	neurexin family protein binding	3/1890	14/18639	0.214285714285714	2.11326530612245	0.163121008203687	0.543582223360582
GO:0061665	SUMO ligase activity	3/1890	14/18639	0.214285714285714	2.11326530612245	0.163121008203687	0.543582223360582
GO:0071933	Arp2/3 complex binding	3/1890	14/18639	0.214285714285714	2.11326530612245	0.163121008203687	0.543582223360582
GO:0005246	calcium channel regulator activity	8/1890	53/18639	0.150943396226415	1.48858939802336	0.16430306132818	0.544427940502697
GO:0016251	RNA polymerase II general transcription initiation factor activity	8/1890	53/18639	0.150943396226415	1.48858939802336	0.16430306132818	0.544427940502697
GO:0106222	lncRNA binding	5/1890	29/18639	0.172413793103448	1.70032840722496	0.164987297463593	0.545155211055758
GO:0004715	non-membrane spanning protein tyrosine kinase activity	7/1890	45/18639	0.155555555555556	1.53407407407407	0.166478934512258	0.54853873646876
GO:0070851	growth factor receptor binding	18/1890	139/18639	0.129496402877698	1.27708119218911	0.167275552672834	0.549619673067884
GO:0004896	cytokine receptor activity	13/1890	96/18639	0.135416666666667	1.33546626984127	0.172312558444506	0.564588354903366
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	8/1890	54/18639	0.148148148148148	1.46102292768959	0.176902666584633	0.57683139566398
GO:0004407	histone deacetylase activity	4/1890	22/18639	0.181818181818182	1.79307359307359	0.178016168141825	0.57683139566398
GO:0033558	protein lysine deacetylase activity	4/1890	22/18639	0.181818181818182	1.79307359307359	0.178016168141825	0.57683139566398
GO:0061133	endopeptidase activator activity	4/1890	22/18639	0.181818181818182	1.79307359307359	0.178016168141825	0.57683139566398
GO:0030276	clathrin binding	7/1890	46/18639	0.152173913043478	1.50072463768116	0.180357009550409	0.582806534993469
GO:0035401	histone H3Y41 kinase activity	15/1890	115/18639	0.130434782608696	1.28633540372671	0.186659950742607	0.599868828002954
GO:0140801	histone H2AXY142 kinase activity	15/1890	115/18639	0.130434782608696	1.28633540372671	0.186659950742607	0.599868828002954
GO:0048531	beta-1,3-galactosyltransferase activity	3/1890	15/18639	0.2	1.97238095238095	0.189423690156612	0.600452345128493
GO:0120283	protein serine/threonine kinase binding	3/1890	15/18639	0.2	1.97238095238095	0.189423690156612	0.600452345128493
GO:0141050	histone H3K deacetylase activity	3/1890	15/18639	0.2	1.97238095238095	0.189423690156612	0.600452345128493
GO:0141051	histone H4K deacetylase activity	3/1890	15/18639	0.2	1.97238095238095	0.189423690156612	0.600452345128493
GO:0008374	O-acyltransferase activity	8/1890	55/18639	0.145454545454545	1.43445887445887	0.189912890061953	0.600452345128493
GO:0140313	molecular sequestering activity	8/1890	55/18639	0.145454545454545	1.43445887445887	0.189912890061953	0.600452345128493
GO:0004725	protein tyrosine phosphatase activity	13/1890	98/18639	0.13265306122449	1.30821185617104	0.191387440255755	0.603487815645163
GO:0001784	phosphotyrosine residue binding	7/1890	47/18639	0.148936170212766	1.46879432624113	0.194700473702005	0.607174016930644
GO:0043495	protein-membrane adaptor activity	7/1890	47/18639	0.148936170212766	1.46879432624113	0.194700473702005	0.607174016930644
GO:0061733	protein-lysine-acetyltransferase activity	7/1890	47/18639	0.148936170212766	1.46879432624113	0.194700473702005	0.607174016930644
GO:0140359	ABC-type transporter activity	7/1890	47/18639	0.148936170212766	1.46879432624113	0.194700473702005	0.607174016930644
GO:0001618	virus receptor activity	11/1890	81/18639	0.135802469135802	1.33927101704879	0.195144590266712	0.607174016930644
GO:0016758	hexosyltransferase activity	24/1890	197/18639	0.121827411167513	1.20145032632342	0.198752454419527	0.607437650622115
GO:0000295	adenine nucleotide transmembrane transporter activity	4/1890	23/18639	0.173913043478261	1.71511387163561	0.199372118916892	0.607437650622115
GO:0003887	DNA-directed DNA polymerase activity	4/1890	23/18639	0.173913043478261	1.71511387163561	0.199372118916892	0.607437650622115
GO:0017134	fibroblast growth factor binding	4/1890	23/18639	0.173913043478261	1.71511387163561	0.199372118916892	0.607437650622115
GO:0042171	lysophosphatidic acid acyltransferase activity	4/1890	23/18639	0.173913043478261	1.71511387163561	0.199372118916892	0.607437650622115
GO:0043274	phospholipase binding	4/1890	23/18639	0.173913043478261	1.71511387163561	0.199372118916892	0.607437650622115
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/1890	23/18639	0.173913043478261	1.71511387163561	0.199372118916892	0.607437650622115
GO:0071617	lysophospholipid acyltransferase activity	4/1890	23/18639	0.173913043478261	1.71511387163561	0.199372118916892	0.607437650622115
GO:0016411	acylglycerol O-acyltransferase activity	5/1890	31/18639	0.161290322580645	1.59062980030722	0.200803324836932	0.610213212522595
GO:0140272	exogenous protein binding	11/1890	82/18639	0.134146341463415	1.32293844367015	0.206203926082476	0.625005698436033
GO:0022804	active transmembrane transporter activity	52/1890	457/18639	0.113785557986871	1.12214233614671	0.207068124412073	0.626007499833406
GO:0160215	deacylase activity	9/1890	65/18639	0.138461538461538	1.36549450549451	0.209564256200125	0.630260685522385
GO:0003684	damaged DNA binding	10/1890	74/18639	0.135135135135135	1.33268983268983	0.214153097914266	0.630260685522385
GO:0031491	nucleosome binding	10/1890	74/18639	0.135135135135135	1.33268983268983	0.214153097914266	0.630260685522385
GO:0004177	aminopeptidase activity	6/1890	40/18639	0.15	1.47928571428571	0.215134683175914	0.630260685522385
GO:0015036	disulfide oxidoreductase activity	6/1890	40/18639	0.15	1.47928571428571	0.215134683175914	0.630260685522385
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	6/1890	40/18639	0.15	1.47928571428571	0.215134683175914	0.630260685522385
GO:0061791	GTPase motor activity	6/1890	40/18639	0.15	1.47928571428571	0.215134683175914	0.630260685522385
GO:0140662	ATP-dependent protein folding chaperone	6/1890	40/18639	0.15	1.47928571428571	0.215134683175914	0.630260685522385
GO:1990606	membrane scission GTPase motor activity	6/1890	40/18639	0.15	1.47928571428571	0.215134683175914	0.630260685522385
GO:0008194	UDP-glycosyltransferase activity	18/1890	145/18639	0.124137931034483	1.22423645320197	0.21547746630446	0.630260685522385
GO:0015562	efflux transmembrane transporter activity	3/1890	16/18639	0.1875	1.84910714285714	0.216697926120511	0.630260685522385
GO:0017070	U6 snRNA binding	3/1890	16/18639	0.1875	1.84910714285714	0.216697926120511	0.630260685522385
GO:0022858	alanine transmembrane transporter activity	3/1890	16/18639	0.1875	1.84910714285714	0.216697926120511	0.630260685522385
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3/1890	16/18639	0.1875	1.84910714285714	0.216697926120511	0.630260685522385
GO:0140327	flippase activity	3/1890	16/18639	0.1875	1.84910714285714	0.216697926120511	0.630260685522385
GO:0016504	peptidase activator activity	8/1890	57/18639	0.140350877192982	1.38412698412698	0.21707188145869	0.630260685522385
GO:0030515	snoRNA binding	5/1890	32/18639	0.15625	1.54092261904762	0.219616877959192	0.633543989035629
GO:0043425	bHLH transcription factor binding	5/1890	32/18639	0.15625	1.54092261904762	0.219616877959192	0.633543989035629
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/1890	24/18639	0.166666666666667	1.64365079365079	0.221443338026094	0.633543989035629
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/1890	24/18639	0.166666666666667	1.64365079365079	0.221443338026094	0.633543989035629
GO:0005315	phosphate transmembrane transporter activity	4/1890	24/18639	0.166666666666667	1.64365079365079	0.221443338026094	0.633543989035629
GO:0030552	cAMP binding	4/1890	24/18639	0.166666666666667	1.64365079365079	0.221443338026094	0.633543989035629
GO:0016763	pentosyltransferase activity	7/1890	49/18639	0.142857142857143	1.40884353741497	0.224655385729355	0.639613513253721
GO:0035254	glutamate receptor binding	7/1890	49/18639	0.142857142857143	1.40884353741497	0.224655385729355	0.639613513253721
GO:0008094	ATP-dependent activity, acting on DNA	25/1890	210/18639	0.119047619047619	1.17403628117914	0.2263511190711	0.642881023415014
GO:0004527	exonuclease activity	11/1890	84/18639	0.130952380952381	1.29143990929705	0.229091321271812	0.649092076936801
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	27/1890	229/18639	0.117903930131004	1.16275733000624	0.230814982285338	0.651318778692864
GO:0001727	lipid kinase activity	6/1890	41/18639	0.146341463414634	1.44320557491289	0.232098251912717	0.651318778692864
GO:0015175	neutral L-amino acid transmembrane transporter activity	6/1890	41/18639	0.146341463414634	1.44320557491289	0.232098251912717	0.651318778692864
GO:0042169	SH2 domain binding	6/1890	41/18639	0.146341463414634	1.44320557491289	0.232098251912717	0.651318778692864
GO:0032813	tumor necrosis factor receptor superfamily binding	7/1890	50/18639	0.14	1.38066666666667	0.240199027255849	0.672236366404389
GO:0003707	nuclear steroid receptor activity	4/1890	25/18639	0.16	1.57790476190476	0.244111964677586	0.672236366404389
GO:0008483	transaminase activity	4/1890	25/18639	0.16	1.57790476190476	0.244111964677586	0.672236366404389
GO:0017025	TBP-class protein binding	4/1890	25/18639	0.16	1.57790476190476	0.244111964677586	0.672236366404389
GO:0019211	phosphatase activator activity	4/1890	25/18639	0.16	1.57790476190476	0.244111964677586	0.672236366404389
GO:0047617	fatty acyl-CoA hydrolase activity	4/1890	25/18639	0.16	1.57790476190476	0.244111964677586	0.672236366404389
GO:0004550	nucleoside diphosphate kinase activity	3/1890	17/18639	0.176470588235294	1.74033613445378	0.244710083934079	0.672236366404389
GO:0046965	nuclear retinoid X receptor binding	3/1890	17/18639	0.176470588235294	1.74033613445378	0.244710083934079	0.672236366404389
GO:1990226	histone methyltransferase binding	3/1890	17/18639	0.176470588235294	1.74033613445378	0.244710083934079	0.672236366404389
GO:0015078	proton transmembrane transporter activity	22/1890	185/18639	0.118918918918919	1.17276705276705	0.245555988520941	0.672984052652019
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	54/1890	484/18639	0.111570247933884	1.10029515938607	0.246606113592912	0.674233834673334
GO:0005548	phospholipid transporter activity	9/1890	68/18639	0.132352941176471	1.30525210084034	0.249160197338042	0.674233834673334
GO:0140223	general transcription initiation factor activity	9/1890	68/18639	0.132352941176471	1.30525210084034	0.249160197338042	0.674233834673334
GO:0004402	histone acetyltransferase activity	6/1890	42/18639	0.142857142857143	1.40884353741497	0.249460770885104	0.674233834673334
GO:0016859	cis-trans isomerase activity	6/1890	42/18639	0.142857142857143	1.40884353741497	0.249460770885104	0.674233834673334
GO:0019894	kinesin binding	6/1890	42/18639	0.142857142857143	1.40884353741497	0.249460770885104	0.674233834673334
GO:0015035	protein-disulfide reductase activity	5/1890	34/18639	0.147058823529412	1.45028011204482	0.258700466785807	0.688264782662112
GO:0016831	carboxy-lyase activity	5/1890	34/18639	0.147058823529412	1.45028011204482	0.258700466785807	0.688264782662112
GO:0001098	basal transcription machinery binding	8/1890	60/18639	0.133333333333333	1.31492063492063	0.260274292759287	0.688264782662112
GO:0001099	basal RNA polymerase II transcription machinery binding	8/1890	60/18639	0.133333333333333	1.31492063492063	0.260274292759287	0.688264782662112
GO:0001637	G protein-coupled chemoattractant receptor activity	4/1890	26/18639	0.153846153846154	1.51721611721612	0.26726174359681	0.688264782662112
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/1890	26/18639	0.153846153846154	1.51721611721612	0.26726174359681	0.688264782662112
GO:0004950	chemokine receptor activity	4/1890	26/18639	0.153846153846154	1.51721611721612	0.26726174359681	0.688264782662112
GO:0005112	Notch binding	4/1890	26/18639	0.153846153846154	1.51721611721612	0.26726174359681	0.688264782662112
GO:0015216	purine nucleotide transmembrane transporter activity	4/1890	26/18639	0.153846153846154	1.51721611721612	0.26726174359681	0.688264782662112
GO:0016289	acyl-CoA hydrolase activity	4/1890	26/18639	0.153846153846154	1.51721611721612	0.26726174359681	0.688264782662112
GO:0051139	metal cation:proton antiporter activity	4/1890	26/18639	0.153846153846154	1.51721611721612	0.26726174359681	0.688264782662112
GO:0052742	phosphatidylinositol kinase activity	4/1890	26/18639	0.153846153846154	1.51721611721612	0.26726174359681	0.688264782662112
GO:0070006	metalloaminopeptidase activity	4/1890	26/18639	0.153846153846154	1.51721611721612	0.26726174359681	0.688264782662112
GO:0070412	R-SMAD binding	4/1890	26/18639	0.153846153846154	1.51721611721612	0.26726174359681	0.688264782662112
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/1890	10/18639	0.2	1.97238095238095	0.269321001911261	0.688264782662112
GO:0008519	ammonium channel activity	2/1890	10/18639	0.2	1.97238095238095	0.269321001911261	0.688264782662112
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/1890	10/18639	0.2	1.97238095238095	0.269321001911261	0.688264782662112
GO:0015187	glycine transmembrane transporter activity	2/1890	10/18639	0.2	1.97238095238095	0.269321001911261	0.688264782662112
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/1890	10/18639	0.2	1.97238095238095	0.269321001911261	0.688264782662112
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/1890	10/18639	0.2	1.97238095238095	0.269321001911261	0.688264782662112
GO:0032395	MHC class II receptor activity	2/1890	10/18639	0.2	1.97238095238095	0.269321001911261	0.688264782662112
GO:0035256	G protein-coupled glutamate receptor binding	2/1890	10/18639	0.2	1.97238095238095	0.269321001911261	0.688264782662112
GO:0042975	peroxisome proliferator activated receptor binding	2/1890	10/18639	0.2	1.97238095238095	0.269321001911261	0.688264782662112
GO:0099122	RNA polymerase II C-terminal domain binding	2/1890	10/18639	0.2	1.97238095238095	0.269321001911261	0.688264782662112
GO:1990763	arrestin family protein binding	2/1890	10/18639	0.2	1.97238095238095	0.269321001911261	0.688264782662112
GO:0030159	signaling receptor complex adaptor activity	7/1890	52/18639	0.134615384615385	1.3275641025641	0.272241097898051	0.690755950362488
GO:0000400	four-way junction DNA binding	3/1890	18/18639	0.166666666666667	1.64365079365079	0.273240205428981	0.690755950362488
GO:0000900	mRNA regulatory element binding translation repressor activity	3/1890	18/18639	0.166666666666667	1.64365079365079	0.273240205428981	0.690755950362488
GO:0017075	syntaxin-1 binding	3/1890	18/18639	0.166666666666667	1.64365079365079	0.273240205428981	0.690755950362488
GO:0031690	adrenergic receptor binding	3/1890	18/18639	0.166666666666667	1.64365079365079	0.273240205428981	0.690755950362488
GO:0000149	SNARE binding	13/1890	106/18639	0.122641509433962	1.20947888589398	0.276267843426258	0.696907914707529
GO:0016651	oxidoreductase activity, acting on NAD(P)H	11/1890	88/18639	0.125	1.2327380952381	0.27754855130019	0.698636160247045
GO:0010485	histone H4 acetyltransferase activity	5/1890	35/18639	0.142857142857143	1.40884353741497	0.27882677252471	0.698854282417702
GO:0034061	DNA polymerase activity	5/1890	35/18639	0.142857142857143	1.40884353741497	0.27882677252471	0.698854282417702
GO:0001216	DNA-binding transcription activator activity	54/1890	491/18639	0.109979633401222	1.08460867035205	0.282490934838994	0.706528500141024
GO:0001223	transcription coactivator binding	6/1890	44/18639	0.136363636363636	1.34480519480519	0.285185093548771	0.710238035525919
GO:0019205	nucleobase-containing compound kinase activity	6/1890	44/18639	0.136363636363636	1.34480519480519	0.285185093548771	0.710238035525919
GO:0016860	intramolecular oxidoreductase activity	7/1890	53/18639	0.132075471698113	1.30251572327044	0.288666451289119	0.711981669116475
GO:0034212	protein N-acetyltransferase activity	7/1890	53/18639	0.132075471698113	1.30251572327044	0.288666451289119	0.711981669116475
GO:0140296	general transcription initiation factor binding	7/1890	53/18639	0.132075471698113	1.30251572327044	0.288666451289119	0.711981669116475
GO:1901505	carbohydrate derivative transmembrane transporter activity	7/1890	53/18639	0.132075471698113	1.30251572327044	0.288666451289119	0.711981669116475
GO:0035091	phosphatidylinositol binding	32/1890	284/18639	0.112676056338028	1.11120053655265	0.289992435494619	0.711981669116475
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	11/1890	89/18639	0.123595505617978	1.21888710540396	0.290134047602451	0.711981669116475
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	11/1890	89/18639	0.123595505617978	1.21888710540396	0.290134047602451	0.711981669116475
GO:0005496	steroid binding	13/1890	108/18639	0.12037037037037	1.1870811287478	0.299222596807971	0.718257708903004
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	5/1890	36/18639	0.138888888888889	1.36970899470899	0.299247649231253	0.718257708903004
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	5/1890	36/18639	0.138888888888889	1.36970899470899	0.299247649231253	0.718257708903004
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	5/1890	36/18639	0.138888888888889	1.36970899470899	0.299247649231253	0.718257708903004
GO:0003756	protein disulfide isomerase activity	3/1890	19/18639	0.157894736842105	1.55714285714286	0.302084034156366	0.718257708903004
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	3/1890	19/18639	0.157894736842105	1.55714285714286	0.302084034156366	0.718257708903004
GO:0031420	alkali metal ion binding	3/1890	19/18639	0.157894736842105	1.55714285714286	0.302084034156366	0.718257708903004
GO:0042577	lipid phosphatase activity	3/1890	19/18639	0.157894736842105	1.55714285714286	0.302084034156366	0.718257708903004
GO:0140793	histone H2AXY142 phosphatase activity	11/1890	90/18639	0.122222222222222	1.20534391534392	0.302876440715894	0.718257708903004
GO:0015101	organic cation transmembrane transporter activity	10/1890	81/18639	0.123456790123457	1.217519106408	0.304314353069354	0.718257708903004
GO:0030971	receptor tyrosine kinase binding	10/1890	81/18639	0.123456790123457	1.217519106408	0.304314353069354	0.718257708903004
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/1890	11/18639	0.181818181818182	1.79307359307359	0.308612007917403	0.718257708903004
GO:0003953	NAD+ nucleosidase activity	2/1890	11/18639	0.181818181818182	1.79307359307359	0.308612007917403	0.718257708903004
GO:0005114	type II transforming growth factor beta receptor binding	2/1890	11/18639	0.181818181818182	1.79307359307359	0.308612007917403	0.718257708903004
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	2/1890	11/18639	0.181818181818182	1.79307359307359	0.308612007917403	0.718257708903004
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/1890	11/18639	0.181818181818182	1.79307359307359	0.308612007917403	0.718257708903004
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/1890	11/18639	0.181818181818182	1.79307359307359	0.308612007917403	0.718257708903004
GO:0019215	intermediate filament binding	2/1890	11/18639	0.181818181818182	1.79307359307359	0.308612007917403	0.718257708903004
GO:0032050	clathrin heavy chain binding	2/1890	11/18639	0.181818181818182	1.79307359307359	0.308612007917403	0.718257708903004
GO:0032404	mismatch repair complex binding	2/1890	11/18639	0.181818181818182	1.79307359307359	0.308612007917403	0.718257708903004
GO:0032794	GTPase activating protein binding	2/1890	11/18639	0.181818181818182	1.79307359307359	0.308612007917403	0.718257708903004
GO:0034511	U3 snoRNA binding	2/1890	11/18639	0.181818181818182	1.79307359307359	0.308612007917403	0.718257708903004
GO:0042608	T cell receptor binding	2/1890	11/18639	0.181818181818182	1.79307359307359	0.308612007917403	0.718257708903004
GO:0050786	RAGE receptor binding	2/1890	11/18639	0.181818181818182	1.79307359307359	0.308612007917403	0.718257708903004
GO:0070697	activin receptor binding	2/1890	11/18639	0.181818181818182	1.79307359307359	0.308612007917403	0.718257708903004
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/1890	11/18639	0.181818181818182	1.79307359307359	0.308612007917403	0.718257708903004
GO:0019213	deacetylase activity	5/1890	37/18639	0.135135135135135	1.33268983268983	0.319893284014756	0.74303925178081
GO:0030291	protein serine/threonine kinase inhibitor activity	6/1890	46/18639	0.130434782608696	1.28633540372671	0.321911165054986	0.746248609900194
GO:0001614	purinergic nucleotide receptor activity	3/1890	20/18639	0.15	1.47928571428571	0.331054249408189	0.758958600682899
GO:0010851	cyclase regulator activity	3/1890	20/18639	0.15	1.47928571428571	0.331054249408189	0.758958600682899
GO:0016502	nucleotide receptor activity	3/1890	20/18639	0.15	1.47928571428571	0.331054249408189	0.758958600682899
GO:0030742	GTP-dependent protein binding	3/1890	20/18639	0.15	1.47928571428571	0.331054249408189	0.758958600682899
GO:0005096	GTPase activator activity	30/1890	271/18639	0.11070110701107	1.0917237743806	0.333159764359807	0.758958600682899
GO:0120013	lipid transfer activity	8/1890	65/18639	0.123076923076923	1.21377289377289	0.337004104058147	0.758958600682899
GO:0003785	actin monomer binding	4/1890	29/18639	0.137931034482759	1.36026272577997	0.338486729310947	0.758958600682899
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	4/1890	29/18639	0.137931034482759	1.36026272577997	0.338486729310947	0.758958600682899
GO:0097472	cyclin-dependent protein kinase activity	4/1890	29/18639	0.137931034482759	1.36026272577997	0.338486729310947	0.758958600682899
GO:0004540	RNA nuclease activity	14/1890	121/18639	0.115702479338843	1.14104683195592	0.34246922564967	0.758958600682899
GO:0000340	RNA 7-methylguanosine cap binding	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0004300	enoyl-CoA hydratase activity	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0004859	phospholipase inhibitor activity	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0005078	MAP-kinase scaffold activity	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0005436	sodium:phosphate symporter activity	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0008179	adenylate cyclase binding	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0015132	prostaglandin transmembrane transporter activity	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0015166	polyol transmembrane transporter activity	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0015368	calcium:monoatomic cation antiporter activity	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0016801	hydrolase activity, acting on ether bonds	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0016803	ether hydrolase activity	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0034452	dynactin binding	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0045295	gamma-catenin binding	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0097371	MDM2/MDM4 family protein binding	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/1890	12/18639	0.166666666666667	1.64365079365079	0.347451635606749	0.758958600682899
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/1890	21/18639	0.142857142857143	1.40884353741497	0.359981070970002	0.777297714351252
GO:0005123	death receptor binding	3/1890	21/18639	0.142857142857143	1.40884353741497	0.359981070970002	0.777297714351252
GO:0008373	sialyltransferase activity	3/1890	21/18639	0.142857142857143	1.40884353741497	0.359981070970002	0.777297714351252
GO:0010314	phosphatidylinositol-5-phosphate binding	3/1890	21/18639	0.142857142857143	1.40884353741497	0.359981070970002	0.777297714351252
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	5/1890	39/18639	0.128205128205128	1.26434676434676	0.36158945138219	0.777297714351252
GO:0016776	phosphotransferase activity, phosphate group as acceptor	5/1890	39/18639	0.128205128205128	1.26434676434676	0.36158945138219	0.777297714351252
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	5/1890	39/18639	0.128205128205128	1.26434676434676	0.36158945138219	0.777297714351252
GO:0016769	transferase activity, transferring nitrogenous groups	4/1890	30/18639	0.133333333333333	1.31492063492063	0.362473870204719	0.777297714351252
GO:0031210	phosphatidylcholine binding	4/1890	30/18639	0.133333333333333	1.31492063492063	0.362473870204719	0.777297714351252
GO:0048019	receptor antagonist activity	4/1890	30/18639	0.133333333333333	1.31492063492063	0.362473870204719	0.777297714351252
GO:0005035	death receptor activity	2/1890	13/18639	0.153846153846154	1.51721611721612	0.385527538790804	0.808669291955
GO:0005338	nucleotide-sugar transmembrane transporter activity	2/1890	13/18639	0.153846153846154	1.51721611721612	0.385527538790804	0.808669291955
GO:0008253	5'-nucleotidase activity	2/1890	13/18639	0.153846153846154	1.51721611721612	0.385527538790804	0.808669291955
GO:0019104	DNA N-glycosylase activity	2/1890	13/18639	0.153846153846154	1.51721611721612	0.385527538790804	0.808669291955
GO:0019855	calcium channel inhibitor activity	2/1890	13/18639	0.153846153846154	1.51721611721612	0.385527538790804	0.808669291955
GO:0030955	potassium ion binding	2/1890	13/18639	0.153846153846154	1.51721611721612	0.385527538790804	0.808669291955
GO:0043560	insulin receptor substrate binding	2/1890	13/18639	0.153846153846154	1.51721611721612	0.385527538790804	0.808669291955
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/1890	13/18639	0.153846153846154	1.51721611721612	0.385527538790804	0.808669291955
GO:0071714	icosanoid transmembrane transporter activity	2/1890	13/18639	0.153846153846154	1.51721611721612	0.385527538790804	0.808669291955
GO:0005164	tumor necrosis factor receptor binding	4/1890	31/18639	0.129032258064516	1.27250384024578	0.386425062111057	0.808669291955
GO:0047499	calcium-independent phospholipase A2 activity	4/1890	31/18639	0.129032258064516	1.27250384024578	0.386425062111057	0.808669291955
GO:0070273	phosphatidylinositol-4-phosphate binding	4/1890	31/18639	0.129032258064516	1.27250384024578	0.386425062111057	0.808669291955
GO:0019903	protein phosphatase binding	16/1890	144/18639	0.111111111111111	1.0957671957672	0.388639875004643	0.808669291955
GO:0008093	cytoskeletal anchor activity	3/1890	22/18639	0.136363636363636	1.34480519480519	0.388712371416556	0.808669291955
GO:0008970	phospholipase A1 activity	3/1890	22/18639	0.136363636363636	1.34480519480519	0.388712371416556	0.808669291955
GO:0031683	G-protein beta/gamma-subunit complex binding	3/1890	22/18639	0.136363636363636	1.34480519480519	0.388712371416556	0.808669291955
GO:0140097	catalytic activity, acting on DNA	36/1890	336/18639	0.107142857142857	1.05663265306122	0.3888230866689	0.808669291955
GO:0070888	E-box binding	7/1890	59/18639	0.11864406779661	1.17005649717514	0.390566276110746	0.810857065270629
GO:0008080	N-acetyltransferase activity	8/1890	69/18639	0.115942028985507	1.14340924775707	0.400582122563144	0.830181678032806
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	5/1890	41/18639	0.121951219512195	1.20267131242741	0.403402298516669	0.834551845079458
GO:0008378	galactosyltransferase activity	4/1890	32/18639	0.125	1.2327380952381	0.410254802704181	0.844261199249131
GO:0047498	calcium-dependent phospholipase A2 activity	4/1890	32/18639	0.125	1.2327380952381	0.410254802704181	0.844261199249131
GO:0120015	sterol transfer activity	4/1890	32/18639	0.125	1.2327380952381	0.410254802704181	0.844261199249131
GO:0016830	carbon-carbon lyase activity	6/1890	51/18639	0.117647058823529	1.16022408963585	0.415591069317998	0.848808698170196
GO:0005158	insulin receptor binding	3/1890	23/18639	0.130434782608696	1.28633540372671	0.417113409291506	0.848808698170196
GO:0005283	amino acid:sodium symporter activity	3/1890	23/18639	0.130434782608696	1.28633540372671	0.417113409291506	0.848808698170196
GO:0016493	C-C chemokine receptor activity	3/1890	23/18639	0.130434782608696	1.28633540372671	0.417113409291506	0.848808698170196
GO:0070577	lysine-acetylated histone binding	3/1890	23/18639	0.130434782608696	1.28633540372671	0.417113409291506	0.848808698170196
GO:0008191	metalloendopeptidase inhibitor activity	2/1890	14/18639	0.142857142857143	1.40884353741497	0.422595293888657	0.848808698170196
GO:0008195	phosphatidate phosphatase activity	2/1890	14/18639	0.142857142857143	1.40884353741497	0.422595293888657	0.848808698170196
GO:0008474	palmitoyl-(protein) hydrolase activity	2/1890	14/18639	0.142857142857143	1.40884353741497	0.422595293888657	0.848808698170196
GO:0032454	histone H3K9 demethylase activity	2/1890	14/18639	0.142857142857143	1.40884353741497	0.422595293888657	0.848808698170196
GO:0034236	protein kinase A catalytic subunit binding	2/1890	14/18639	0.142857142857143	1.40884353741497	0.422595293888657	0.848808698170196
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	2/1890	14/18639	0.142857142857143	1.40884353741497	0.422595293888657	0.848808698170196
GO:0044548	S100 protein binding	2/1890	14/18639	0.142857142857143	1.40884353741497	0.422595293888657	0.848808698170196
GO:0070742	C2H2 zinc finger domain binding	2/1890	14/18639	0.142857142857143	1.40884353741497	0.422595293888657	0.848808698170196
GO:0098599	palmitoyl hydrolase activity	2/1890	14/18639	0.142857142857143	1.40884353741497	0.422595293888657	0.848808698170196
GO:0051879	Hsp90 protein binding	5/1890	42/18639	0.119047619047619	1.17403628117914	0.42420520765607	0.850585826633453
GO:0019905	syntaxin binding	7/1890	61/18639	0.114754098360656	1.13169398907104	0.424957194982516	0.850639572891624
GO:0005543	phospholipid binding	52/1890	497/18639	0.104627766599598	1.03182906965603	0.42674046343404	0.852753941410782
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	4/1890	33/18639	0.121212121212121	1.1953823953824	0.433884447014246	0.865555197870256
GO:0015179	L-amino acid transmembrane transporter activity	7/1890	62/18639	0.112903225806452	1.11344086021505	0.442082647965741	0.873014619514307
GO:0005319	lipid transporter activity	19/1890	178/18639	0.106741573033708	1.05267522739433	0.442503555618046	0.873014619514307
GO:0048156	tau protein binding	5/1890	43/18639	0.116279069767442	1.14673311184939	0.44486734775306	0.873014619514307
GO:0004806	triacylglycerol lipase activity	3/1890	24/18639	0.125	1.2327380952381	0.445066276615137	0.873014619514307
GO:0015295	solute:proton symporter activity	3/1890	24/18639	0.125	1.2327380952381	0.445066276615137	0.873014619514307
GO:0019957	C-C chemokine binding	3/1890	24/18639	0.125	1.2327380952381	0.445066276615137	0.873014619514307
GO:0050699	WW domain binding	3/1890	24/18639	0.125	1.2327380952381	0.445066276615137	0.873014619514307
GO:0070300	phosphatidic acid binding	3/1890	24/18639	0.125	1.2327380952381	0.445066276615137	0.873014619514307
GO:0140033	acetylation-dependent protein binding	3/1890	24/18639	0.125	1.2327380952381	0.445066276615137	0.873014619514307
GO:0140612	DNA damage sensor activity	3/1890	24/18639	0.125	1.2327380952381	0.445066276615137	0.873014619514307
GO:1902936	phosphatidylinositol bisphosphate binding	12/1890	111/18639	0.108108108108108	1.06615186615187	0.452812358896495	0.88451116129346
GO:0008376	acetylgalactosaminyltransferase activity	4/1890	34/18639	0.117647058823529	1.16022408963585	0.457242311044704	0.88451116129346
GO:0004559	alpha-mannosidase activity	2/1890	15/18639	0.133333333333333	1.31492063492063	0.458467848308972	0.88451116129346
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/1890	15/18639	0.133333333333333	1.31492063492063	0.458467848308972	0.88451116129346
GO:0008252	nucleotidase activity	2/1890	15/18639	0.133333333333333	1.31492063492063	0.458467848308972	0.88451116129346
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/1890	15/18639	0.133333333333333	1.31492063492063	0.458467848308972	0.88451116129346
GO:0033130	acetylcholine receptor binding	2/1890	15/18639	0.133333333333333	1.31492063492063	0.458467848308972	0.88451116129346
GO:0034483	heparan sulfate sulfotransferase activity	2/1890	15/18639	0.133333333333333	1.31492063492063	0.458467848308972	0.88451116129346
GO:0047372	monoacylglycerol lipase activity	2/1890	15/18639	0.133333333333333	1.31492063492063	0.458467848308972	0.88451116129346
GO:0140776	protein-containing complex destabilizing activity	2/1890	15/18639	0.133333333333333	1.31492063492063	0.458467848308972	0.88451116129346
GO:0016790	thiolester hydrolase activity	5/1890	44/18639	0.113636363636364	1.120670995671	0.465339431625406	0.894824841469837
GO:0030547	signaling receptor inhibitor activity	5/1890	44/18639	0.113636363636364	1.120670995671	0.465339431625406	0.894824841469837
GO:0015485	cholesterol binding	6/1890	54/18639	0.111111111111111	1.0957671957672	0.47132484908738	0.903372627417478
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	6/1890	54/18639	0.111111111111111	1.0957671957672	0.47132484908738	0.903372627417478
GO:0051213	dioxygenase activity	10/1890	93/18639	0.10752688172043	1.06041986687148	0.472161268786707	0.903499458869179
GO:0004623	phospholipase A2 activity	4/1890	35/18639	0.114285714285714	1.12707482993197	0.480263670853736	0.917506980311779
GO:0098632	cell-cell adhesion mediator activity	6/1890	55/18639	0.109090909090909	1.07584415584416	0.489592237639155	0.928244811096545
GO:0003688	DNA replication origin binding	2/1890	16/18639	0.125	1.2327380952381	0.493006408621609	0.928244811096545
GO:0004707	MAP kinase activity	2/1890	16/18639	0.125	1.2327380952381	0.493006408621609	0.928244811096545
GO:0005159	insulin-like growth factor receptor binding	2/1890	16/18639	0.125	1.2327380952381	0.493006408621609	0.928244811096545
GO:0005324	long-chain fatty acid transmembrane transporter activity	2/1890	16/18639	0.125	1.2327380952381	0.493006408621609	0.928244811096545
GO:0015923	mannosidase activity	2/1890	16/18639	0.125	1.2327380952381	0.493006408621609	0.928244811096545
GO:0043023	ribosomal large subunit binding	2/1890	16/18639	0.125	1.2327380952381	0.493006408621609	0.928244811096545
GO:0055102	lipase inhibitor activity	2/1890	16/18639	0.125	1.2327380952381	0.493006408621609	0.928244811096545
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/1890	16/18639	0.125	1.2327380952381	0.493006408621609	0.928244811096545
GO:0003730	mRNA 3'-UTR binding	27/1890	262/18639	0.103053435114504	1.01630316248637	0.494825002124832	0.930175845340429
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	3/1890	26/18639	0.115384615384615	1.13791208791209	0.499235319125687	0.9339761233404
GO:0097602	cullin family protein binding	3/1890	26/18639	0.115384615384615	1.13791208791209	0.499235319125687	0.9339761233404
GO:0120014	phospholipid transfer activity	3/1890	26/18639	0.115384615384615	1.13791208791209	0.499235319125687	0.9339761233404
GO:0004180	carboxypeptidase activity	5/1890	46/18639	0.108695652173913	1.07194616977226	0.505535028753709	0.944255714535192
GO:0019212	phosphatase inhibitor activity	6/1890	56/18639	0.107142857142857	1.05663265306122	0.50764927206103	0.946697291140839
GO:0008235	metalloexopeptidase activity	7/1890	66/18639	0.106060606060606	1.0459595959596	0.509437861894264	0.948524780955511
GO:0051536	iron-sulfur cluster binding	8/1890	76/18639	0.105263157894737	1.03809523809524	0.511005513596843	0.9499357645786
GO:1901981	phosphatidylinositol phosphate binding	19/1890	185/18639	0.102702702702703	1.01284427284427	0.512502445892557	0.951211026949318
GO:0016407	acetyltransferase activity	10/1890	96/18639	0.104166666666667	1.02728174603175	0.513697852134101	0.951923507983097
GO:0008013	beta-catenin binding	11/1890	106/18639	0.10377358490566	1.02340521114106	0.51488631154365	0.952620888707731
GO:0015294	solute:monoatomic cation symporter activity	12/1890	116/18639	0.103448275862069	1.02019704433498	0.515996222847105	0.9527293654157
GO:0140375	immune receptor activity	16/1890	156/18639	0.102564102564103	1.01147741147741	0.519872003011313	0.9527293654157
GO:0030551	cyclic nucleotide binding	4/1890	37/18639	0.108108108108108	1.06615186615187	0.525072175319187	0.9527293654157
GO:0008173	RNA methyltransferase activity	7/1890	67/18639	0.104477611940299	1.03034825870647	0.525859451755582	0.9527293654157
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	7/1890	67/18639	0.104477611940299	1.03034825870647	0.525859451755582	0.9527293654157
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/1890	17/18639	0.117647058823529	1.16022408963585	0.526112585246613	0.9527293654157
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	2/1890	17/18639	0.117647058823529	1.16022408963585	0.526112585246613	0.9527293654157
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/1890	17/18639	0.117647058823529	1.16022408963585	0.526112585246613	0.9527293654157
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/1890	17/18639	0.117647058823529	1.16022408963585	0.526112585246613	0.9527293654157
GO:0016805	dipeptidase activity	2/1890	17/18639	0.117647058823529	1.16022408963585	0.526112585246613	0.9527293654157
GO:0045125	bioactive lipid receptor activity	2/1890	17/18639	0.117647058823529	1.16022408963585	0.526112585246613	0.9527293654157
GO:0070402	NADPH binding	2/1890	17/18639	0.117647058823529	1.16022408963585	0.526112585246613	0.9527293654157
GO:0070403	NAD+ binding	2/1890	17/18639	0.117647058823529	1.16022408963585	0.526112585246613	0.9527293654157
GO:0051540	metal cluster binding	8/1890	77/18639	0.103896103896104	1.02461348175634	0.526315966572356	0.9527293654157
GO:1990782	protein tyrosine kinase binding	12/1890	117/18639	0.102564102564103	1.01147741147741	0.528406027826402	0.955038937812587
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	17/1890	167/18639	0.101796407185629	1.00390647276875	0.531122424920176	0.958471699125179
GO:0004857	enzyme inhibitor activity	42/1890	416/18639	0.100961538461538	0.995673076923077	0.536407886174998	0.966522965412094
GO:0016247	channel regulator activity	17/1890	168/18639	0.101190476190476	0.997930839002268	0.541444880262562	0.974102522312862
GO:0005109	frizzled binding	4/1890	38/18639	0.105263157894737	1.03809523809524	0.546763520000941	0.977673184391927
GO:0042162	telomeric DNA binding	4/1890	38/18639	0.105263157894737	1.03809523809524	0.546763520000941	0.977673184391927
GO:0042887	amide transmembrane transporter activity	4/1890	38/18639	0.105263157894737	1.03809523809524	0.546763520000941	0.977673184391927
GO:0043531	ADP binding	4/1890	38/18639	0.105263157894737	1.03809523809524	0.546763520000941	0.977673184391927
GO:0050698	proteoglycan sulfotransferase activity	3/1890	28/18639	0.107142857142857	1.05663265306122	0.550580693327184	0.979914543291477
GO:0097718	disordered domain specific binding	3/1890	28/18639	0.107142857142857	1.05663265306122	0.550580693327184	0.979914543291477
GO:0004518	nuclease activity	21/1890	209/18639	0.100478468899522	0.990909090909091	0.551740289530884	0.979914543291477
GO:0015370	solute:sodium symporter activity	8/1890	79/18639	0.10126582278481	0.998673899939723	0.556390123045483	0.979914543291477
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/1890	18/18639	0.111111111111111	1.0957671957672	0.557721632723817	0.979914543291477
GO:0008525	phosphatidylcholine transporter activity	2/1890	18/18639	0.111111111111111	1.0957671957672	0.557721632723817	0.979914543291477
GO:0015172	acidic amino acid transmembrane transporter activity	2/1890	18/18639	0.111111111111111	1.0957671957672	0.557721632723817	0.979914543291477
GO:0017128	phospholipid scramblase activity	2/1890	18/18639	0.111111111111111	1.0957671957672	0.557721632723817	0.979914543291477
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	2/1890	18/18639	0.111111111111111	1.0957671957672	0.557721632723817	0.979914543291477
GO:0070064	proline-rich region binding	2/1890	18/18639	0.111111111111111	1.0957671957672	0.557721632723817	0.979914543291477
GO:1901611	phosphatidylglycerol binding	2/1890	18/18639	0.111111111111111	1.0957671957672	0.557721632723817	0.979914543291477
GO:0016279	protein-lysine N-methyltransferase activity	7/1890	69/18639	0.101449275362319	1.00048309178744	0.55804170069796	0.979914543291477
GO:0141108	transporter regulator activity	17/1890	170/18639	0.1	0.986190476190476	0.561872890435982	0.985167265293583
GO:0048306	calcium-dependent protein binding	8/1890	80/18639	0.1	0.986190476190476	0.571120623012381	0.999887299691825
GO:0016278	lysine N-methyltransferase activity	7/1890	70/18639	0.1	0.986190476190476	0.57376316291501	0.999999999996313
GO:0005416	amino acid:monoatomic cation symporter activity	3/1890	29/18639	0.103448275862069	1.02019704433498	0.575053073790596	0.999999999996313
GO:0035250	UDP-galactosyltransferase activity	3/1890	29/18639	0.103448275862069	1.02019704433498	0.575053073790596	0.999999999996313
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	3/1890	29/18639	0.103448275862069	1.02019704433498	0.575053073790596	0.999999999996313
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/1890	19/18639	0.105263157894737	1.03809523809524	0.587796644319988	0.999999999996313
GO:0008301	DNA binding, bending	2/1890	19/18639	0.105263157894737	1.03809523809524	0.587796644319988	0.999999999996313
GO:0008574	plus-end-directed microtubule motor activity	2/1890	19/18639	0.105263157894737	1.03809523809524	0.587796644319988	0.999999999996313
GO:0015245	fatty acid transmembrane transporter activity	2/1890	19/18639	0.105263157894737	1.03809523809524	0.587796644319988	0.999999999996313
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	2/1890	19/18639	0.105263157894737	1.03809523809524	0.587796644319988	0.999999999996313
GO:0046527	glucosyltransferase activity	2/1890	19/18639	0.105263157894737	1.03809523809524	0.587796644319988	0.999999999996313
GO:0046624	sphingolipid transporter activity	2/1890	19/18639	0.105263157894737	1.03809523809524	0.587796644319988	0.999999999996313
GO:0050145	nucleoside monophosphate kinase activity	2/1890	19/18639	0.105263157894737	1.03809523809524	0.587796644319988	0.999999999996313
GO:0050997	quaternary ammonium group binding	4/1890	40/18639	0.1	0.986190476190476	0.58852790509737	0.999999999996313
GO:0140299	molecular sensor activity	7/1890	71/18639	0.0985915492957746	0.972300469483568	0.589214808044964	0.999999999996313
GO:0043178	alcohol binding	9/1890	92/18639	0.0978260869565217	0.964751552795031	0.596279427339707	0.999999999996313
GO:0001968	fibronectin binding	3/1890	30/18639	0.1	0.986190476190476	0.598672985300138	0.999999999996313
GO:0043995	histone H4K5 acetyltransferase activity	3/1890	30/18639	0.1	0.986190476190476	0.598672985300138	0.999999999996313
GO:0043996	histone H4K8 acetyltransferase activity	3/1890	30/18639	0.1	0.986190476190476	0.598672985300138	0.999999999996313
GO:0043997	histone H4K12 acetyltransferase activity	3/1890	30/18639	0.1	0.986190476190476	0.598672985300138	0.999999999996313
GO:0051721	protein phosphatase 2A binding	3/1890	30/18639	0.1	0.986190476190476	0.598672985300138	0.999999999996313
GO:0003823	antigen binding	17/1890	174/18639	0.0977011494252874	0.96351943076081	0.60170323407777	0.999999999996313
GO:0019955	cytokine binding	14/1890	144/18639	0.0972222222222222	0.958796296296296	0.607032315772036	0.999999999996313
GO:0017080	sodium channel regulator activity	4/1890	41/18639	0.0975609756097561	0.962137049941928	0.608541484187175	0.999999999996313
GO:0140828	metal cation:monoatomic cation antiporter activity	4/1890	41/18639	0.0975609756097561	0.962137049941928	0.608541484187175	0.999999999996313
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	2/1890	20/18639	0.1	0.986190476190476	0.616323577087966	0.999999999996313
GO:0015095	magnesium ion transmembrane transporter activity	2/1890	20/18639	0.1	0.986190476190476	0.616323577087966	0.999999999996313
GO:0016505	peptidase activator activity involved in apoptotic process	2/1890	20/18639	0.1	0.986190476190476	0.616323577087966	0.999999999996313
GO:0140664	ATP-dependent DNA damage sensor activity	2/1890	20/18639	0.1	0.986190476190476	0.616323577087966	0.999999999996313
GO:0008327	methyl-CpG binding	3/1890	31/18639	0.0967741935483871	0.954377880184332	0.621413834213254	0.999999999996313
GO:0016410	N-acyltransferase activity	9/1890	94/18639	0.0957446808510638	0.944224924012158	0.622652076979016	0.999999999996313
GO:0004864	protein phosphatase inhibitor activity	5/1890	53/18639	0.0943396226415094	0.9303683737646	0.634754178053906	0.999999999996313
GO:0051018	protein kinase A binding	5/1890	53/18639	0.0943396226415094	0.9303683737646	0.634754178053906	0.999999999996313
GO:0015174	basic amino acid transmembrane transporter activity	2/1890	21/18639	0.0952380952380952	0.939229024943311	0.643306998784593	0.999999999996313
GO:0051428	peptide hormone receptor binding	2/1890	21/18639	0.0952380952380952	0.939229024943311	0.643306998784593	0.999999999996313
GO:0001094	TFIID-class transcription factor complex binding	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0004935	adrenergic receptor activity	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0004955	prostaglandin receptor activity	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0005031	tumor necrosis factor receptor activity	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0005131	growth hormone receptor binding	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0005381	iron ion transmembrane transporter activity	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0005522	profilin binding	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0008190	eukaryotic initiation factor 4E binding	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0015203	polyamine transmembrane transporter activity	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0031419	cobalamin binding	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0031434	mitogen-activated protein kinase kinase binding	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0033204	ribonuclease P RNA binding	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0043121	neurotrophin binding	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0043208	glycosphingolipid binding	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0050308	sugar-phosphatase activity	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0050815	phosphoserine residue binding	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0051880	G-quadruplex DNA binding	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0070513	death domain binding	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0098505	G-rich strand telomeric DNA binding	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0140135	mechanosensitive monoatomic cation channel activity	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0141109	transporter activator activity	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/1890	10/18639	0.1	0.986190476190476	0.656802288776501	0.999999999996313
GO:0098631	cell adhesion mediator activity	7/1890	76/18639	0.0921052631578947	0.908333333333333	0.66193909755035	0.999999999996313
GO:0099106	ion channel regulator activity	15/1890	160/18639	0.09375	0.924553571428571	0.664730064112728	0.999999999996313
GO:0015377	chloride:monoatomic cation symporter activity	2/1890	22/18639	0.0909090909090909	0.896536796536797	0.668766461521397	0.999999999996313
GO:0034062	5'-3' RNA polymerase activity	2/1890	22/18639	0.0909090909090909	0.896536796536797	0.668766461521397	0.999999999996313
GO:0046972	histone H4K16 acetyltransferase activity	2/1890	22/18639	0.0909090909090909	0.896536796536797	0.668766461521397	0.999999999996313
GO:0070034	telomerase RNA binding	2/1890	22/18639	0.0909090909090909	0.896536796536797	0.668766461521397	0.999999999996313
GO:0097747	RNA polymerase activity	2/1890	22/18639	0.0909090909090909	0.896536796536797	0.668766461521397	0.999999999996313
GO:0008170	N-methyltransferase activity	9/1890	98/18639	0.0918367346938776	0.905685131195335	0.672538505349631	0.999999999996313
GO:0005126	cytokine receptor binding	26/1890	275/18639	0.0945454545454545	0.932398268398268	0.677116301724581	0.999999999996313
GO:0170055	lipid transmembrane transporter activity	5/1890	56/18639	0.0892857142857143	0.880527210884354	0.683297344016192	0.999999999996313
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	3/1890	34/18639	0.0882352941176471	0.870168067226891	0.684222914779221	0.999999999996313
GO:0042054	histone methyltransferase activity	6/1890	67/18639	0.0895522388059701	0.883155650319829	0.685634730932264	0.999999999996313
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0000099	sulfur amino acid transmembrane transporter activity	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0002162	dystroglycan binding	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0004954	prostanoid receptor activity	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0008526	phosphatidylinositol transfer activity	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0015217	ADP transmembrane transporter activity	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0019203	carbohydrate phosphatase activity	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0034056	estrogen response element binding	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0045294	alpha-catenin binding	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0047676	arachidonate-CoA ligase activity	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0140031	phosphorylation-dependent protein binding	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0180030	inositol phosphate kinase activity	1/1890	11/18639	0.0909090909090909	0.896536796536797	0.691621316862411	0.999999999996313
GO:0004602	glutathione peroxidase activity	2/1890	23/18639	0.0869565217391304	0.857556935817805	0.692733418876625	0.999999999996313
GO:0008171	O-methyltransferase activity	2/1890	23/18639	0.0869565217391304	0.857556935817805	0.692733418876625	0.999999999996313
GO:0031681	G-protein beta-subunit binding	2/1890	23/18639	0.0869565217391304	0.857556935817805	0.692733418876625	0.999999999996313
GO:0005343	organic acid:sodium symporter activity	3/1890	35/18639	0.0857142857142857	0.84530612244898	0.703344093897235	0.999999999996313
GO:0008514	organic anion transmembrane transporter activity	25/1890	269/18639	0.0929368029739777	0.916533899805275	0.707712080361843	0.999999999996313
GO:0005200	structural constituent of cytoskeleton	10/1890	112/18639	0.0892857142857143	0.880527210884354	0.710469493009756	0.999999999996313
GO:0042625	ATPase-coupled ion transmembrane transporter activity	2/1890	24/18639	0.0833333333333333	0.821825396825397	0.715248613627669	0.999999999996313
GO:0043998	histone H2A acetyltransferase activity	2/1890	24/18639	0.0833333333333333	0.821825396825397	0.715248613627669	0.999999999996313
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	2/1890	24/18639	0.0833333333333333	0.821825396825397	0.715248613627669	0.999999999996313
GO:0046961	proton-transporting ATPase activity, rotational mechanism	2/1890	24/18639	0.0833333333333333	0.821825396825397	0.715248613627669	0.999999999996313
GO:0050431	transforming growth factor beta binding	2/1890	24/18639	0.0833333333333333	0.821825396825397	0.715248613627669	0.999999999996313
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/1890	24/18639	0.0833333333333333	0.821825396825397	0.715248613627669	0.999999999996313
GO:0070840	dynein complex binding	2/1890	24/18639	0.0833333333333333	0.821825396825397	0.715248613627669	0.999999999996313
GO:0008238	exopeptidase activity	9/1890	102/18639	0.0882352941176471	0.870168067226891	0.718265138934872	0.999999999996313
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0003720	telomerase activity	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0004000	adenosine deaminase activity	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0004526	ribonuclease P activity	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0005049	nuclear export signal receptor activity	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0005247	voltage-gated chloride channel activity	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0008603	cAMP-dependent protein kinase regulator activity	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0016423	tRNA (guanine) methyltransferase activity	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0016840	carbon-nitrogen lyase activity	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0031543	peptidyl-proline dioxygenase activity	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0035251	UDP-glucosyltransferase activity	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0035497	cAMP response element binding	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0042301	phosphate ion binding	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0043047	single-stranded telomeric DNA binding	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0070008	serine-type exopeptidase activity	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0070679	inositol 1,4,5 trisphosphate binding	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/1890	12/18639	0.0833333333333333	0.821825396825397	0.722909469703835	0.999999999996313
GO:0015459	potassium channel regulator activity	5/1890	59/18639	0.0847457627118644	0.835754640839387	0.727293187326464	0.999999999996313
GO:0005253	monoatomic anion channel activity	9/1890	103/18639	0.087378640776699	0.861719833564494	0.729014893284306	0.999999999996313
GO:0032266	phosphatidylinositol-3-phosphate binding	4/1890	48/18639	0.0833333333333333	0.821825396825397	0.730915932015825	0.999999999996313
GO:0015296	monoatomic anion:monoatomic cation symporter activity	2/1890	25/18639	0.08	0.788952380952381	0.736359872435823	0.999999999996313
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	2/1890	25/18639	0.08	0.788952380952381	0.736359872435823	0.999999999996313
GO:0120020	cholesterol transfer activity	2/1890	25/18639	0.08	0.788952380952381	0.736359872435823	0.999999999996313
GO:0015085	calcium ion transmembrane transporter activity	13/1890	147/18639	0.0884353741496599	0.87214123744736	0.738655767853103	0.999999999996313
GO:0022829	wide pore channel activity	3/1890	37/18639	0.0810810810810811	0.7996138996139	0.738904922415099	0.999999999996313
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	5/1890	60/18639	0.0833333333333333	0.821825396825397	0.740936231251467	0.999999999996313
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/1890	13/18639	0.0769230769230769	0.758608058608059	0.751024630613254	0.999999999996313
GO:0003964	RNA-directed DNA polymerase activity	1/1890	13/18639	0.0769230769230769	0.758608058608059	0.751024630613254	0.999999999996313
GO:0004465	lipoprotein lipase activity	1/1890	13/18639	0.0769230769230769	0.758608058608059	0.751024630613254	0.999999999996313
GO:0005172	vascular endothelial growth factor receptor binding	1/1890	13/18639	0.0769230769230769	0.758608058608059	0.751024630613254	0.999999999996313
GO:0005542	folic acid binding	1/1890	13/18639	0.0769230769230769	0.758608058608059	0.751024630613254	0.999999999996313
GO:0008035	high-density lipoprotein particle binding	1/1890	13/18639	0.0769230769230769	0.758608058608059	0.751024630613254	0.999999999996313
GO:0031994	insulin-like growth factor I binding	1/1890	13/18639	0.0769230769230769	0.758608058608059	0.751024630613254	0.999999999996313
GO:0035673	oligopeptide transmembrane transporter activity	1/1890	13/18639	0.0769230769230769	0.758608058608059	0.751024630613254	0.999999999996313
GO:0045159	myosin II binding	1/1890	13/18639	0.0769230769230769	0.758608058608059	0.751024630613254	0.999999999996313
GO:0051011	microtubule minus-end binding	1/1890	13/18639	0.0769230769230769	0.758608058608059	0.751024630613254	0.999999999996313
GO:0061459	L-arginine transmembrane transporter activity	1/1890	13/18639	0.0769230769230769	0.758608058608059	0.751024630613254	0.999999999996313
GO:0071837	HMG box domain binding	1/1890	13/18639	0.0769230769230769	0.758608058608059	0.751024630613254	0.999999999996313
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/1890	13/18639	0.0769230769230769	0.758608058608059	0.751024630613254	0.999999999996313
GO:0089720	caspase binding	1/1890	13/18639	0.0769230769230769	0.758608058608059	0.751024630613254	0.999999999996313
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/1890	13/18639	0.0769230769230769	0.758608058608059	0.751024630613254	0.999999999996313
GO:1901338	catecholamine binding	1/1890	13/18639	0.0769230769230769	0.758608058608059	0.751024630613254	0.999999999996313
GO:0008509	monoatomic anion transmembrane transporter activity	13/1890	149/18639	0.087248322147651	0.86043464365612	0.755808238489507	0.999999999996313
GO:0004435	phosphatidylinositol phospholipase C activity	2/1890	26/18639	0.0769230769230769	0.758608058608059	0.756120251878335	0.999999999996313
GO:0004529	DNA exonuclease activity	2/1890	26/18639	0.0769230769230769	0.758608058608059	0.756120251878335	0.999999999996313
GO:0008157	protein phosphatase 1 binding	2/1890	26/18639	0.0769230769230769	0.758608058608059	0.756120251878335	0.999999999996313
GO:0030247	polysaccharide binding	2/1890	26/18639	0.0769230769230769	0.758608058608059	0.756120251878335	0.999999999996313
GO:0034237	protein kinase A regulatory subunit binding	2/1890	26/18639	0.0769230769230769	0.758608058608059	0.756120251878335	0.999999999996313
GO:0043548	phosphatidylinositol 3-kinase binding	2/1890	26/18639	0.0769230769230769	0.758608058608059	0.756120251878335	0.999999999996313
GO:0050750	low-density lipoprotein particle receptor binding	2/1890	26/18639	0.0769230769230769	0.758608058608059	0.756120251878335	0.999999999996313
GO:0008276	protein methyltransferase activity	8/1890	95/18639	0.0842105263157895	0.83047619047619	0.75964042444694	0.999999999996313
GO:0008168	methyltransferase activity	18/1890	204/18639	0.0882352941176471	0.870168067226891	0.76709291333433	0.999999999996313
GO:0016741	transferase activity, transferring one-carbon groups	19/1890	215/18639	0.0883720930232558	0.871517165005537	0.769501383601918	0.999999999996313
GO:0000217	DNA secondary structure binding	3/1890	39/18639	0.0769230769230769	0.758608058608059	0.770994845044081	0.999999999996313
GO:0003678	DNA helicase activity	6/1890	74/18639	0.0810810810810811	0.7996138996139	0.774060031963442	0.999999999996313
GO:0005104	fibroblast growth factor receptor binding	2/1890	27/18639	0.0740740740740741	0.730511463844797	0.774586487306425	0.999999999996313
GO:0015252	proton channel activity	2/1890	27/18639	0.0740740740740741	0.730511463844797	0.774586487306425	0.999999999996313
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	2/1890	27/18639	0.0740740740740741	0.730511463844797	0.774586487306425	0.999999999996313
GO:0004705	JUN kinase activity	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:0005313	L-glutamate transmembrane transporter activity	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:0008494	translation activator activity	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:0008559	ABC-type xenobiotic transporter activity	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:0015386	potassium:proton antiporter activity	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:0015926	glucosidase activity	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:0016530	metallochaperone activity	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:0019992	diacylglycerol binding	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:0031404	chloride ion binding	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:0042813	Wnt receptor activity	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:0043176	amine binding	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:0046030	inositol trisphosphate phosphatase activity	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:0098847	sequence-specific single stranded DNA binding	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:1901474	azole transmembrane transporter activity	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:1901612	cardiolipin binding	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:1990825	sequence-specific mRNA binding	1/1890	14/18639	0.0714285714285714	0.704421768707483	0.776288425745915	0.999999999996313
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	11/1890	130/18639	0.0846153846153846	0.834468864468865	0.778511709836588	0.999999999996313
GO:0005507	copper ion binding	5/1890	63/18639	0.0793650793650794	0.782690854119426	0.778831771799404	0.999999999996313
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	7/1890	86/18639	0.0813953488372093	0.802713178294574	0.781616496567306	0.999999999996313
GO:0071949	FAD binding	3/1890	40/18639	0.075	0.739642857142857	0.785789461796517	0.999999999996313
GO:0005516	calmodulin binding	18/1890	207/18639	0.0869565217391304	0.857556935817805	0.787505350813209	0.999999999996313
GO:0008081	phosphoric diester hydrolase activity	7/1890	87/18639	0.0804597701149425	0.793486590038314	0.791621577550313	0.999999999996313
GO:0036408	histone H3K14 acetyltransferase activity	2/1890	28/18639	0.0714285714285714	0.704421768707483	0.791817702227905	0.999999999996313
GO:0004089	carbonate dehydratase activity	1/1890	15/18639	0.0666666666666667	0.657460317460317	0.79898989556284	0.999999999996313
GO:0004129	cytochrome-c oxidase activity	1/1890	15/18639	0.0666666666666667	0.657460317460317	0.79898989556284	0.999999999996313
GO:0004467	long-chain fatty acid-CoA ligase activity	1/1890	15/18639	0.0666666666666667	0.657460317460317	0.79898989556284	0.999999999996313
GO:0004953	icosanoid receptor activity	1/1890	15/18639	0.0666666666666667	0.657460317460317	0.79898989556284	0.999999999996313
GO:0005041	low-density lipoprotein particle receptor activity	1/1890	15/18639	0.0666666666666667	0.657460317460317	0.79898989556284	0.999999999996313
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/1890	15/18639	0.0666666666666667	0.657460317460317	0.79898989556284	0.999999999996313
GO:0010181	FMN binding	1/1890	15/18639	0.0666666666666667	0.657460317460317	0.79898989556284	0.999999999996313
GO:0015250	water channel activity	1/1890	15/18639	0.0666666666666667	0.657460317460317	0.79898989556284	0.999999999996313
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/1890	15/18639	0.0666666666666667	0.657460317460317	0.79898989556284	0.999999999996313
GO:0017081	chloride channel regulator activity	1/1890	15/18639	0.0666666666666667	0.657460317460317	0.79898989556284	0.999999999996313
GO:0050780	dopamine receptor binding	1/1890	15/18639	0.0666666666666667	0.657460317460317	0.79898989556284	0.999999999996313
GO:0005544	calcium-dependent phospholipid binding	4/1890	53/18639	0.0754716981132075	0.74429469901168	0.799096026051604	0.999999999996313
GO:0016877	ligase activity, forming carbon-sulfur bonds	3/1890	41/18639	0.0731707317073171	0.721602787456446	0.799782723186728	0.999999999996313
GO:0038024	cargo receptor activity	5/1890	65/18639	0.0769230769230769	0.758608058608059	0.801625963138742	0.999999999996313
GO:0046982	protein heterodimerization activity	33/1890	369/18639	0.0894308943089431	0.881958962446767	0.802549267915477	0.999999999996313
GO:0046943	carboxylic acid transmembrane transporter activity	16/1890	188/18639	0.0851063829787234	0.839311043566363	0.804510566654678	0.999999999996313
GO:0004629	phospholipase C activity	2/1890	29/18639	0.0689655172413793	0.680131362889984	0.80787434137141	0.999999999996313
GO:0010484	histone H3 acetyltransferase activity	2/1890	29/18639	0.0689655172413793	0.680131362889984	0.80787434137141	0.999999999996313
GO:0051861	glycolipid binding	2/1890	29/18639	0.0689655172413793	0.680131362889984	0.80787434137141	0.999999999996313
GO:0099604	ligand-gated calcium channel activity	2/1890	29/18639	0.0689655172413793	0.680131362889984	0.80787434137141	0.999999999996313
GO:0050661	NADP binding	4/1890	54/18639	0.0740740740740741	0.730511463844797	0.810909256920265	0.999999999996313
GO:0005342	organic acid transmembrane transporter activity	16/1890	189/18639	0.0846560846560847	0.834870244394054	0.810982129398529	0.999999999996313
GO:0031492	nucleosomal DNA binding	3/1890	42/18639	0.0714285714285714	0.704421768707483	0.813000986295754	0.999999999996313
GO:0042056	chemoattractant activity	3/1890	42/18639	0.0714285714285714	0.704421768707483	0.813000986295754	0.999999999996313
GO:0015291	secondary active transmembrane transporter activity	25/1890	287/18639	0.0871080139372822	0.85905093744815	0.816710606003094	0.999999999996313
GO:0015293	symporter activity	12/1890	146/18639	0.0821917808219178	0.810567514677104	0.817080975341313	0.999999999996313
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/1890	16/18639	0.0625	0.616369047619048	0.819388794692256	0.999999999996313
GO:0005149	interleukin-1 receptor binding	1/1890	16/18639	0.0625	0.616369047619048	0.819388794692256	0.999999999996313
GO:0008296	3'-5'-DNA exonuclease activity	1/1890	16/18639	0.0625	0.616369047619048	0.819388794692256	0.999999999996313
GO:0015378	sodium:chloride symporter activity	1/1890	16/18639	0.0625	0.616369047619048	0.819388794692256	0.999999999996313
GO:0015385	sodium:proton antiporter activity	1/1890	16/18639	0.0625	0.616369047619048	0.819388794692256	0.999999999996313
GO:0016675	oxidoreductase activity, acting on a heme group of donors	1/1890	16/18639	0.0625	0.616369047619048	0.819388794692256	0.999999999996313
GO:0016722	oxidoreductase activity, acting on metal ions	1/1890	16/18639	0.0625	0.616369047619048	0.819388794692256	0.999999999996313
GO:0030275	LRR domain binding	1/1890	16/18639	0.0625	0.616369047619048	0.819388794692256	0.999999999996313
GO:0097027	ubiquitin-protein transferase activator activity	1/1890	16/18639	0.0625	0.616369047619048	0.819388794692256	0.999999999996313
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/1890	16/18639	0.0625	0.616369047619048	0.819388794692256	0.999999999996313
GO:0001965	G-protein alpha-subunit binding	2/1890	30/18639	0.0666666666666667	0.657460317460317	0.8228172953765	0.999999999996313
GO:0033612	receptor serine/threonine kinase binding	2/1890	30/18639	0.0666666666666667	0.657460317460317	0.8228172953765	0.999999999996313
GO:0016853	isomerase activity	15/1890	180/18639	0.0833333333333333	0.821825396825397	0.823197548012935	0.999999999996313
GO:0015171	amino acid transmembrane transporter activity	8/1890	102/18639	0.0784313725490196	0.773482726423903	0.82414622096221	0.999999999996313
GO:0016835	carbon-oxygen lyase activity	6/1890	79/18639	0.0759493670886076	0.749005424954792	0.824824548802071	0.999999999996313
GO:0008200	ion channel inhibitor activity	3/1890	43/18639	0.0697674418604651	0.688039867109634	0.825471870598567	0.999999999996313
GO:0052689	carboxylic ester hydrolase activity	7/1890	92/18639	0.0760869565217391	0.75036231884058	0.836497930669253	0.999999999996313
GO:0017147	Wnt-protein binding	2/1890	31/18639	0.0645161290322581	0.636251920122888	0.836707189249828	0.999999999996313
GO:0070325	lipoprotein particle receptor binding	2/1890	31/18639	0.0645161290322581	0.636251920122888	0.836707189249828	0.999999999996313
GO:0016248	channel inhibitor activity	3/1890	44/18639	0.0681818181818182	0.672402597402597	0.837223897326154	0.999999999996313
GO:0030020	extracellular matrix structural constituent conferring tensile strength	3/1890	44/18639	0.0681818181818182	0.672402597402597	0.837223897326154	0.999999999996313
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0004549	tRNA-specific ribonuclease activity	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0004659	prenyltransferase activity	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0005092	GDP-dissociation inhibitor activity	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0008484	sulfuric ester hydrolase activity	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0008569	minus-end-directed microtubule motor activity	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0009881	photoreceptor activity	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0015278	intracellularly gated calcium channel activity	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0017110	nucleoside diphosphate phosphatase activity	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0019198	transmembrane receptor protein phosphatase activity	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0030169	low-density lipoprotein particle binding	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0031489	myosin V binding	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0032977	membrane insertase activity	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0038191	neuropilin binding	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0045236	CXCR chemokine receptor binding	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0048038	quinone binding	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0070492	oligosaccharide binding	1/1890	17/18639	0.0588235294117647	0.580112044817927	0.837718557782608	0.999999999996313
GO:0046915	transition metal ion transmembrane transporter activity	3/1890	45/18639	0.0666666666666667	0.657460317460317	0.848286172070824	0.999999999996313
GO:0051539	4 iron, 4 sulfur cluster binding	3/1890	45/18639	0.0666666666666667	0.657460317460317	0.848286172070824	0.999999999996313
GO:0141110	transporter inhibitor activity	3/1890	45/18639	0.0666666666666667	0.657460317460317	0.848286172070824	0.999999999996313
GO:0071813	lipoprotein particle binding	2/1890	32/18639	0.0625	0.616369047619048	0.849603810402778	0.999999999996313
GO:0071814	protein-lipid complex binding	2/1890	32/18639	0.0625	0.616369047619048	0.849603810402778	0.999999999996313
GO:0008028	monocarboxylic acid transmembrane transporter activity	5/1890	70/18639	0.0714285714285714	0.704421768707483	0.850489867867625	0.999999999996313
GO:0042562	hormone binding	7/1890	94/18639	0.074468085106383	0.734397163120567	0.852148697535657	0.999999999996313
GO:0005372	water transmembrane transporter activity	1/1890	18/18639	0.0555555555555556	0.547883597883598	0.854188965139008	0.999999999996313
GO:0008409	5'-3' exonuclease activity	1/1890	18/18639	0.0555555555555556	0.547883597883598	0.854188965139008	0.999999999996313
GO:0015373	monoatomic anion:sodium symporter activity	1/1890	18/18639	0.0555555555555556	0.547883597883598	0.854188965139008	0.999999999996313
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/1890	18/18639	0.0555555555555556	0.547883597883598	0.854188965139008	0.999999999996313
GO:0016854	racemase and epimerase activity	1/1890	18/18639	0.0555555555555556	0.547883597883598	0.854188965139008	0.999999999996313
GO:0030228	lipoprotein particle receptor activity	1/1890	18/18639	0.0555555555555556	0.547883597883598	0.854188965139008	0.999999999996313
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/1890	18/18639	0.0555555555555556	0.547883597883598	0.854188965139008	0.999999999996313
GO:0098641	cadherin binding involved in cell-cell adhesion	1/1890	18/18639	0.0555555555555556	0.547883597883598	0.854188965139008	0.999999999996313
GO:0001540	amyloid-beta binding	6/1890	83/18639	0.072289156626506	0.712908777969019	0.858530950712075	0.999999999996313
GO:0019239	deaminase activity	2/1890	33/18639	0.0606060606060606	0.597691197691198	0.861565655302976	0.999999999996313
GO:0042923	neuropeptide binding	2/1890	33/18639	0.0606060606060606	0.597691197691198	0.861565655302976	0.999999999996313
GO:0005262	calcium channel activity	10/1890	131/18639	0.0763358778625954	0.75281715739731	0.866591643099215	0.999999999996313
GO:0005518	collagen binding	5/1890	72/18639	0.0694444444444444	0.684854497354497	0.86702393769507	0.999999999996313
GO:0061749	forked DNA-dependent helicase activity	3/1890	47/18639	0.0638297872340425	0.629483282674772	0.868459181406147	0.999999999996313
GO:1990518	single-stranded 3'-5' DNA helicase activity	3/1890	47/18639	0.0638297872340425	0.629483282674772	0.868459181406147	0.999999999996313
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/1890	19/18639	0.0526315789473684	0.519047619047619	0.868988538517842	0.999999999996313
GO:0005520	insulin-like growth factor binding	1/1890	19/18639	0.0526315789473684	0.519047619047619	0.868988538517842	0.999999999996313
GO:0008381	mechanosensitive monoatomic ion channel activity	1/1890	19/18639	0.0526315789473684	0.519047619047619	0.868988538517842	0.999999999996313
GO:0022821	solute:potassium antiporter activity	1/1890	19/18639	0.0526315789473684	0.519047619047619	0.868988538517842	0.999999999996313
GO:0022840	leak channel activity	1/1890	19/18639	0.0526315789473684	0.519047619047619	0.868988538517842	0.999999999996313
GO:0022842	narrow pore channel activity	1/1890	19/18639	0.0526315789473684	0.519047619047619	0.868988538517842	0.999999999996313
GO:0034987	immunoglobulin receptor binding	1/1890	19/18639	0.0526315789473684	0.519047619047619	0.868988538517842	0.999999999996313
GO:0042834	peptidoglycan binding	1/1890	19/18639	0.0526315789473684	0.519047619047619	0.868988538517842	0.999999999996313
GO:0070003	threonine-type peptidase activity	1/1890	19/18639	0.0526315789473684	0.519047619047619	0.868988538517842	0.999999999996313
GO:0008175	tRNA methyltransferase activity	2/1890	34/18639	0.0588235294117647	0.580112044817927	0.872649576585711	0.999999999996313
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	2/1890	34/18639	0.0588235294117647	0.580112044817927	0.872649576585711	0.999999999996313
GO:0051427	hormone receptor binding	2/1890	34/18639	0.0588235294117647	0.580112044817927	0.872649576585711	0.999999999996313
GO:0052866	phosphatidylinositol phosphate phosphatase activity	2/1890	34/18639	0.0588235294117647	0.580112044817927	0.872649576585711	0.999999999996313
GO:0004620	phospholipase activity	8/1890	109/18639	0.073394495412844	0.723809523809524	0.874353604282603	0.999999999996313
GO:0009378	four-way junction helicase activity	3/1890	48/18639	0.0625	0.616369047619048	0.877628731365502	0.999999999996313
GO:0016879	ligase activity, forming carbon-nitrogen bonds	3/1890	48/18639	0.0625	0.616369047619048	0.877628731365502	0.999999999996313
GO:0036121	double-stranded DNA helicase activity	3/1890	48/18639	0.0625	0.616369047619048	0.877628731365502	0.999999999996313
GO:0038187	pattern recognition receptor activity	3/1890	48/18639	0.0625	0.616369047619048	0.877628731365502	0.999999999996313
GO:0043138	3'-5' DNA helicase activity	3/1890	48/18639	0.0625	0.616369047619048	0.877628731365502	0.999999999996313
GO:0016836	hydro-lyase activity	4/1890	61/18639	0.0655737704918033	0.646682279469165	0.878482125500676	0.999999999996313
GO:0016209	antioxidant activity	6/1890	86/18639	0.0697674418604651	0.688039867109634	0.880143177818754	0.999999999996313
GO:0001972	retinoic acid binding	1/1890	20/18639	0.05	0.493095238095238	0.882286694382572	0.999999999996313
GO:0016408	C-acyltransferase activity	1/1890	20/18639	0.05	0.493095238095238	0.882286694382572	0.999999999996313
GO:0031418	L-ascorbic acid binding	1/1890	20/18639	0.05	0.493095238095238	0.882286694382572	0.999999999996313
GO:0052745	inositol phosphate phosphatase activity	1/1890	20/18639	0.05	0.493095238095238	0.882286694382572	0.999999999996313
GO:0140939	histone H4 methyltransferase activity	1/1890	20/18639	0.05	0.493095238095238	0.882286694382572	0.999999999996313
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	14/1890	181/18639	0.0773480662983425	0.762799263351749	0.888595591388586	0.999999999996313
GO:0015297	antiporter activity	10/1890	135/18639	0.0740740740740741	0.730511463844797	0.888838740556892	0.999999999996313
GO:0004190	aspartic-type endopeptidase activity	2/1890	36/18639	0.0555555555555556	0.547883597883598	0.892401302155199	0.999999999996313
GO:0001846	opsonin binding	1/1890	21/18639	0.0476190476190476	0.469614512471655	0.894235679162471	0.999999999996313
GO:0070182	DNA polymerase binding	1/1890	21/18639	0.0476190476190476	0.469614512471655	0.894235679162471	0.999999999996313
GO:1904047	S-adenosyl-L-methionine binding	1/1890	21/18639	0.0476190476190476	0.469614512471655	0.894235679162471	0.999999999996313
GO:0005007	fibroblast growth factor receptor activity	3/1890	50/18639	0.06	0.591714285714286	0.894278863996473	0.999999999996313
GO:0004536	DNA nuclease activity	4/1890	64/18639	0.0625	0.616369047619048	0.900336391579239	0.999999999996313
GO:0042805	actinin binding	2/1890	37/18639	0.0540540540540541	0.533075933075933	0.901172523854634	0.999999999996313
GO:0070001	aspartic-type peptidase activity	2/1890	37/18639	0.0540540540540541	0.533075933075933	0.901172523854634	0.999999999996313
GO:0008237	metallopeptidase activity	14/1890	184/18639	0.0760869565217391	0.75036231884058	0.901465409219097	0.999999999996313
GO:0008649	rRNA methyltransferase activity	1/1890	22/18639	0.0454545454545455	0.448268398268398	0.904972308573951	0.999999999996313
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/1890	22/18639	0.0454545454545455	0.448268398268398	0.904972308573951	0.999999999996313
GO:0032931	histone H3K56 acetyltransferase activity	1/1890	22/18639	0.0454545454545455	0.448268398268398	0.904972308573951	0.999999999996313
GO:0033691	sialic acid binding	1/1890	22/18639	0.0454545454545455	0.448268398268398	0.904972308573951	0.999999999996313
GO:0043992	histone H3K9 acetyltransferase activity	1/1890	22/18639	0.0454545454545455	0.448268398268398	0.904972308573951	0.999999999996313
GO:0043993	histone H3K18 acetyltransferase activity	1/1890	22/18639	0.0454545454545455	0.448268398268398	0.904972308573951	0.999999999996313
GO:0043994	histone H3K23 acetyltransferase activity	1/1890	22/18639	0.0454545454545455	0.448268398268398	0.904972308573951	0.999999999996313
GO:0043999	histone H2AK5 acetyltransferase activity	1/1890	22/18639	0.0454545454545455	0.448268398268398	0.904972308573951	0.999999999996313
GO:0044012	histone H2AK9 acetyltransferase activity	1/1890	22/18639	0.0454545454545455	0.448268398268398	0.904972308573951	0.999999999996313
GO:0044014	histone H2BK5 acetyltransferase activity	1/1890	22/18639	0.0454545454545455	0.448268398268398	0.904972308573951	0.999999999996313
GO:0044015	histone H2BK12 acetyltransferase activity	1/1890	22/18639	0.0454545454545455	0.448268398268398	0.904972308573951	0.999999999996313
GO:0044016	histone H3K4 acetyltransferase activity	1/1890	22/18639	0.0454545454545455	0.448268398268398	0.904972308573951	0.999999999996313
GO:0044017	histone H3K27 acetyltransferase activity	1/1890	22/18639	0.0454545454545455	0.448268398268398	0.904972308573951	0.999999999996313
GO:0044018	histone H3K36 acetyltransferase activity	1/1890	22/18639	0.0454545454545455	0.448268398268398	0.904972308573951	0.999999999996313
GO:0140908	histone H3K122 acetyltransferase activity	1/1890	22/18639	0.0454545454545455	0.448268398268398	0.904972308573951	0.999999999996313
GO:0004519	endonuclease activity	9/1890	127/18639	0.0708661417322835	0.698875140607424	0.907412757707279	0.999999999996313
GO:0051015	actin filament binding	16/1890	209/18639	0.076555023923445	0.754978354978355	0.909600801003446	0.999999999996313
GO:0005212	structural constituent of eye lens	1/1890	23/18639	0.0434782608695652	0.428778467908903	0.91461953083292	0.999999999996313
GO:0044013	histone H2B acetyltransferase activity	1/1890	23/18639	0.0434782608695652	0.428778467908903	0.91461953083292	0.999999999996313
GO:0140102	catalytic activity, acting on a rRNA	1/1890	23/18639	0.0434782608695652	0.428778467908903	0.91461953083292	0.999999999996313
GO:0008146	sulfotransferase activity	3/1890	53/18639	0.0566037735849057	0.55822102425876	0.915450402800372	0.999999999996313
GO:0003774	cytoskeletal motor activity	11/1890	153/18639	0.0718954248366013	0.709025832555244	0.916962995843832	0.999999999996313
GO:0050840	extracellular matrix binding	4/1890	67/18639	0.0597014925373134	0.588770433546553	0.918644868790595	0.999999999996313
GO:0016298	lipase activity	9/1890	130/18639	0.0692307692307692	0.682747252747253	0.920408775014493	0.999999999996313
GO:0016798	hydrolase activity, acting on glycosyl bonds	9/1890	130/18639	0.0692307692307692	0.682747252747253	0.920408775014493	0.999999999996313
GO:0033218	amide binding	19/1890	247/18639	0.0769230769230769	0.758608058608059	0.922144956479578	0.999999999996313
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/1890	24/18639	0.0416666666666667	0.410912698412698	0.923287831580975	0.999999999996313
GO:0004622	lysophospholipase activity	1/1890	24/18639	0.0416666666666667	0.410912698412698	0.923287831580975	0.999999999996313
GO:0005540	hyaluronic acid binding	1/1890	24/18639	0.0416666666666667	0.410912698412698	0.923287831580975	0.999999999996313
GO:0015149	hexose transmembrane transporter activity	1/1890	24/18639	0.0416666666666667	0.410912698412698	0.923287831580975	0.999999999996313
GO:0055056	D-glucose transmembrane transporter activity	1/1890	24/18639	0.0416666666666667	0.410912698412698	0.923287831580975	0.999999999996313
GO:0015144	carbohydrate transmembrane transporter activity	2/1890	40/18639	0.05	0.493095238095238	0.923639392197226	0.999999999996313
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	2/1890	40/18639	0.05	0.493095238095238	0.923639392197226	0.999999999996313
GO:0003777	microtubule motor activity	4/1890	68/18639	0.0588235294117647	0.580112044817927	0.924042481211216	0.999999999996313
GO:0000030	mannosyltransferase activity	1/1890	25/18639	0.04	0.39447619047619	0.931076496545356	0.999999999996313
GO:0005251	delayed rectifier potassium channel activity	1/1890	25/18639	0.04	0.39447619047619	0.931076496545356	0.999999999996313
GO:0005537	D-mannose binding	1/1890	25/18639	0.04	0.39447619047619	0.931076496545356	0.999999999996313
GO:0015271	outward rectifier potassium channel activity	1/1890	25/18639	0.04	0.39447619047619	0.931076496545356	0.999999999996313
GO:0015645	fatty acid ligase activity	1/1890	25/18639	0.04	0.39447619047619	0.931076496545356	0.999999999996313
GO:0120515	fatty acid-CoA ligase activity	1/1890	25/18639	0.04	0.39447619047619	0.931076496545356	0.999999999996313
GO:0030170	pyridoxal phosphate binding	3/1890	56/18639	0.0535714285714286	0.528316326530612	0.932687030281092	0.999999999996313
GO:0030165	PDZ domain binding	5/1890	83/18639	0.0602409638554217	0.594090648307516	0.93273024743001	0.999999999996313
GO:0016782	transferase activity, transferring sulphur-containing groups	4/1890	70/18639	0.0571428571428571	0.563537414965986	0.933880958708567	0.999999999996313
GO:0004520	DNA endonuclease activity	2/1890	42/18639	0.0476190476190476	0.469614512471655	0.935840517746711	0.999999999996313
GO:0004601	peroxidase activity	3/1890	57/18639	0.0526315789473684	0.519047619047619	0.937671369470212	0.999999999996313
GO:0070279	vitamin B6 binding	3/1890	57/18639	0.0526315789473684	0.519047619047619	0.937671369470212	0.999999999996313
GO:0015145	monosaccharide transmembrane transporter activity	1/1890	26/18639	0.0384615384615385	0.379304029304029	0.938074746332037	0.999999999996313
GO:0030507	spectrin binding	1/1890	26/18639	0.0384615384615385	0.379304029304029	0.938074746332037	0.999999999996313
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/1890	43/18639	0.0465116279069767	0.458693244739756	0.941224354192962	0.999999999996313
GO:0019838	growth factor binding	9/1890	136/18639	0.0661764705882353	0.652626050420168	0.941767811865768	0.999999999996313
GO:0017116	single-stranded DNA helicase activity	3/1890	58/18639	0.0517241379310345	0.510098522167488	0.94231239249098	0.999999999996313
GO:0005178	integrin binding	11/1890	161/18639	0.0683229813664596	0.673794735285419	0.943538130736074	0.999999999996313
GO:0005385	zinc ion transmembrane transporter activity	1/1890	27/18639	0.037037037037037	0.365255731922399	0.94436275629456	0.999999999996313
GO:0016405	CoA-ligase activity	1/1890	27/18639	0.037037037037037	0.365255731922399	0.94436275629456	0.999999999996313
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/1890	27/18639	0.037037037037037	0.365255731922399	0.94436275629456	0.999999999996313
GO:0050660	flavin adenine dinucleotide binding	5/1890	86/18639	0.0581395348837209	0.573366555924695	0.944681590227847	0.999999999996313
GO:0004521	RNA endonuclease activity	4/1890	73/18639	0.0547945205479452	0.540378343118069	0.946483318381461	0.999999999996313
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	3/1890	59/18639	0.0508474576271186	0.501452784503632	0.946631012723153	0.999999999996313
GO:0004175	endopeptidase activity	32/1890	405/18639	0.0790123456790123	0.779212228101117	0.948421193274618	0.999999999996313
GO:0051119	sugar transmembrane transporter activity	1/1890	28/18639	0.0357142857142857	0.352210884353741	0.950012573111844	0.999999999996313
GO:0051393	alpha-actinin binding	1/1890	28/18639	0.0357142857142857	0.352210884353741	0.950012573111844	0.999999999996313
GO:0051959	dynein light intermediate chain binding	1/1890	28/18639	0.0357142857142857	0.352210884353741	0.950012573111844	0.999999999996313
GO:0004714	transmembrane receptor protein tyrosine kinase activity	3/1890	60/18639	0.05	0.493095238095238	0.95064717132097	0.999999999996313
GO:0016829	lyase activity	14/1890	200/18639	0.07	0.690333333333333	0.951077685525197	0.999999999996313
GO:0015081	sodium ion transmembrane transporter activity	11/1890	164/18639	0.0670731707317073	0.661469221835076	0.951400707817921	0.999999999996313
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	3/1890	61/18639	0.0491803278688525	0.485011709601874	0.954379846104778	0.999999999996313
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	2/1890	46/18639	0.0434782608695652	0.428778467908903	0.954913520997683	0.999999999996313
GO:0004181	metallocarboxypeptidase activity	1/1890	29/18639	0.0344827586206897	0.340065681444992	0.955088938531145	0.999999999996313
GO:0043236	laminin binding	1/1890	29/18639	0.0344827586206897	0.340065681444992	0.955088938531145	0.999999999996313
GO:0003779	actin binding	35/1890	443/18639	0.0790067720090293	0.77915726109857	0.955490664806593	0.999999999996313
GO:0016874	ligase activity	11/1890	167/18639	0.0658682634730539	0.649586541203308	0.958284235217985	0.999999999996313
GO:0140938	histone H3 methyltransferase activity	2/1890	47/18639	0.0425531914893617	0.419655521783181	0.958755936090641	0.999999999996313
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/1890	30/18639	0.0333333333333333	0.328730158730159	0.959650029674409	0.999999999996313
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	5/1890	91/18639	0.0549450549450549	0.541862899005756	0.960398344738286	0.999999999996313
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/1890	31/18639	0.032258064516129	0.318125960061444	0.963748124355228	0.999999999996313
GO:0005452	solute:inorganic anion antiporter activity	1/1890	31/18639	0.032258064516129	0.318125960061444	0.963748124355228	0.999999999996313
GO:0016878	acid-thiol ligase activity	1/1890	31/18639	0.032258064516129	0.318125960061444	0.963748124355228	0.999999999996313
GO:0072349	modified amino acid transmembrane transporter activity	1/1890	31/18639	0.032258064516129	0.318125960061444	0.963748124355228	0.999999999996313
GO:0005004	GPI-linked ephrin receptor activity	2/1890	49/18639	0.0408163265306122	0.402526724975705	0.965519692258866	0.999999999996313
GO:0005008	hepatocyte growth factor receptor activity	2/1890	49/18639	0.0408163265306122	0.402526724975705	0.965519692258866	0.999999999996313
GO:0005009	insulin receptor activity	2/1890	49/18639	0.0408163265306122	0.402526724975705	0.965519692258866	0.999999999996313
GO:0005011	macrophage colony-stimulating factor receptor activity	2/1890	49/18639	0.0408163265306122	0.402526724975705	0.965519692258866	0.999999999996313
GO:0005018	platelet-derived growth factor alpha-receptor activity	2/1890	49/18639	0.0408163265306122	0.402526724975705	0.965519692258866	0.999999999996313
GO:0005020	stem cell factor receptor activity	2/1890	49/18639	0.0408163265306122	0.402526724975705	0.965519692258866	0.999999999996313
GO:0008288	boss receptor activity	2/1890	49/18639	0.0408163265306122	0.402526724975705	0.965519692258866	0.999999999996313
GO:0036332	placental growth factor receptor activity	2/1890	49/18639	0.0408163265306122	0.402526724975705	0.965519692258866	0.999999999996313
GO:0038062	protein tyrosine kinase collagen receptor activity	2/1890	49/18639	0.0408163265306122	0.402526724975705	0.965519692258866	0.999999999996313
GO:0060175	brain-derived neurotrophic factor receptor activity	2/1890	49/18639	0.0408163265306122	0.402526724975705	0.965519692258866	0.999999999996313
GO:0015106	bicarbonate transmembrane transporter activity	1/1890	32/18639	0.03125	0.308184523809524	0.967430198998855	0.999999999996313
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/1890	32/18639	0.03125	0.308184523809524	0.967430198998855	0.999999999996313
GO:0042910	xenobiotic transmembrane transporter activity	1/1890	32/18639	0.03125	0.308184523809524	0.967430198998855	0.999999999996313
GO:0005006	epidermal growth factor receptor activity	2/1890	50/18639	0.04	0.39447619047619	0.968488060103132	0.999999999996313
GO:0005017	platelet-derived growth factor receptor activity	2/1890	50/18639	0.04	0.39447619047619	0.968488060103132	0.999999999996313
GO:0005019	platelet-derived growth factor beta-receptor activity	2/1890	50/18639	0.04	0.39447619047619	0.968488060103132	0.999999999996313
GO:0005010	insulin-like growth factor receptor activity	2/1890	51/18639	0.0392156862745098	0.386741363211951	0.971209370564722	0.999999999996313
GO:0005021	vascular endothelial growth factor receptor activity	2/1890	51/18639	0.0392156862745098	0.386741363211951	0.971209370564722	0.999999999996313
GO:0005030	neurotrophin receptor activity	2/1890	51/18639	0.0392156862745098	0.386741363211951	0.971209370564722	0.999999999996313
GO:0016500	protein-hormone receptor activity	3/1890	67/18639	0.0447761194029851	0.441577825159915	0.971768587855656	0.999999999996313
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/1890	34/18639	0.0294117647058824	0.290056022408964	0.973710856577341	0.999999999996313
GO:0090482	vitamin transmembrane transporter activity	1/1890	34/18639	0.0294117647058824	0.290056022408964	0.973710856577341	0.999999999996313
GO:0061134	peptidase regulator activity	15/1890	226/18639	0.0663716814159292	0.654551201011378	0.974686046188126	0.999999999996313
GO:0005003	ephrin receptor activity	2/1890	53/18639	0.0377358490566038	0.37214734950584	0.975987595513722	0.999999999996313
GO:0005005	transmembrane-ephrin receptor activity	2/1890	53/18639	0.0377358490566038	0.37214734950584	0.975987595513722	0.999999999996313
GO:0017046	peptide hormone binding	2/1890	53/18639	0.0377358490566038	0.37214734950584	0.975987595513722	0.999999999996313
GO:0038064	collagen receptor activity	2/1890	53/18639	0.0377358490566038	0.37214734950584	0.975987595513722	0.999999999996313
GO:0140101	catalytic activity, acting on a tRNA	8/1890	139/18639	0.0575539568345324	0.567591640972936	0.976203117157243	0.999999999996313
GO:0016229	steroid dehydrogenase activity	1/1890	35/18639	0.0285714285714286	0.281768707482993	0.976381454861072	0.999999999996313
GO:0051287	NAD binding	2/1890	54/18639	0.037037037037037	0.365255731922399	0.978079430650027	0.999999999996313
GO:0004033	aldo-keto reductase (NADPH) activity	1/1890	36/18639	0.0277777777777778	0.273941798941799	0.978780887795526	0.999999999996313
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/1890	36/18639	0.0277777777777778	0.273941798941799	0.978780887795526	0.999999999996313
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/1890	36/18639	0.0277777777777778	0.273941798941799	0.978780887795526	0.999999999996313
GO:0005506	iron ion binding	9/1890	154/18639	0.0584415584415584	0.576345083487941	0.978782656882285	0.999999999996313
GO:0001653	peptide receptor activity	7/1890	128/18639	0.0546875	0.539322916666667	0.979388851304191	0.999999999996313
GO:0043394	proteoglycan binding	1/1890	37/18639	0.027027027027027	0.266537966537967	0.980936675682773	0.999999999996313
GO:0000146	microfilament motor activity	1/1890	38/18639	0.0263157894736842	0.25952380952381	0.982873547146033	0.999999999996313
GO:0005501	retinoid binding	1/1890	38/18639	0.0263157894736842	0.25952380952381	0.982873547146033	0.999999999996313
GO:0019840	isoprenoid binding	1/1890	38/18639	0.0263157894736842	0.25952380952381	0.982873547146033	0.999999999996313
GO:0061135	endopeptidase regulator activity	11/1890	184/18639	0.0597826086956522	0.589570393374741	0.983280970943765	0.999999999996313
GO:0048029	monosaccharide binding	3/1890	74/18639	0.0405405405405405	0.39980694980695	0.984120388769956	0.999999999996313
GO:0001786	phosphatidylserine binding	2/1890	59/18639	0.0338983050847458	0.334301856335755	0.986154437907179	0.999999999996313
GO:0071855	neuropeptide receptor binding	1/1890	40/18639	0.025	0.246547619047619	0.986177166543339	0.999999999996313
GO:0017022	myosin binding	3/1890	76/18639	0.0394736842105263	0.389285714285714	0.986564210859687	0.999999999996313
GO:0001530	lipopolysaccharide binding	1/1890	41/18639	0.024390243902439	0.240534262485482	0.987581820300697	0.999999999996313
GO:0004812	aminoacyl-tRNA ligase activity	1/1890	41/18639	0.024390243902439	0.240534262485482	0.987581820300697	0.999999999996313
GO:0008227	G protein-coupled amine receptor activity	1/1890	41/18639	0.024390243902439	0.240534262485482	0.987581820300697	0.999999999996313
GO:0016875	ligase activity, forming carbon-oxygen bonds	1/1890	41/18639	0.024390243902439	0.240534262485482	0.987581820300697	0.999999999996313
GO:0008528	G protein-coupled peptide receptor activity	6/1890	122/18639	0.0491803278688525	0.485011709601874	0.987770123848517	0.999999999996313
GO:0019199	transmembrane receptor protein kinase activity	3/1890	78/18639	0.0384615384615385	0.379304029304029	0.988644526131392	0.999999999996313
GO:0030246	carbohydrate binding	18/1890	280/18639	0.0642857142857143	0.633979591836735	0.989036392974619	0.999999999996313
GO:0015103	inorganic anion transmembrane transporter activity	9/1890	165/18639	0.0545454545454545	0.537922077922078	0.989077616001554	0.999999999996313
GO:0005245	voltage-gated calcium channel activity	1/1890	43/18639	0.0232558139534884	0.229346622369878	0.989977599696886	0.999999999996313
GO:1901682	sulfur compound transmembrane transporter activity	2/1890	63/18639	0.0317460317460317	0.31307634164777	0.99045200623773	0.999999999996313
GO:0001664	G protein-coupled receptor binding	19/1890	297/18639	0.063973063973064	0.630896264229598	0.991268069607734	0.999999999996313
GO:0008009	chemokine activity	1/1890	45/18639	0.0222222222222222	0.219153439153439	0.991911369779543	0.999999999996313
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/1890	46/18639	0.0217391304347826	0.214389233954451	0.992733544196917	0.999999999996313
GO:0005244	voltage-gated monoatomic ion channel activity	9/1890	173/18639	0.0520231213872832	0.513047068538398	0.993392363139774	0.999999999996313
GO:0008188	neuropeptide receptor activity	1/1890	48/18639	0.0208333333333333	0.205456349206349	0.994135783212893	0.999999999996313
GO:0022832	voltage-gated channel activity	9/1890	175/18639	0.0514285714285714	0.507183673469388	0.994186592804525	0.999999999996313
GO:0048020	CCR chemokine receptor binding	1/1890	50/18639	0.02	0.197238095238095	0.99526754140038	0.999999999996313
GO:0019842	vitamin binding	7/1890	150/18639	0.0466666666666667	0.460222222222222	0.99529302914907	0.999999999996313
GO:0016597	amino acid binding	1/1890	51/18639	0.0196078431372549	0.193370681605976	0.995748704817094	0.999999999996313
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	5/1890	122/18639	0.040983606557377	0.404176424668228	0.995855710857466	0.999999999996313
GO:0042379	chemokine receptor binding	2/1890	72/18639	0.0277777777777778	0.273941798941799	0.995908400449334	0.999999999996313
GO:0046906	tetrapyrrole binding	7/1890	152/18639	0.0460526315789474	0.454166666666667	0.995909391200473	0.999999999996313
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	1/1890	52/18639	0.0192307692307692	0.189652014652015	0.996180970143955	0.999999999996313
GO:0072341	modified amino acid binding	3/1890	91/18639	0.032967032967033	0.325117739403454	0.996285356415443	0.999999999996313
GO:0046873	metal ion transmembrane transporter activity	30/1890	450/18639	0.0666666666666667	0.657460317460317	0.996353241908211	0.999999999996313
GO:0020037	heme binding	6/1890	142/18639	0.0422535211267606	0.416700201207243	0.997109994396759	0.999999999996313
GO:0008201	heparin binding	8/1890	172/18639	0.0465116279069767	0.458693244739756	0.997220775988354	0.999999999996313
GO:0004866	endopeptidase inhibitor activity	7/1890	161/18639	0.0434782608695652	0.428778467908903	0.997848722139691	0.999999999996313
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	5/1890	132/18639	0.0378787878787879	0.373556998556999	0.998103070613911	0.999999999996313
GO:0005254	chloride channel activity	2/1890	83/18639	0.0240963855421687	0.237636259323006	0.998572552883947	0.999999999996313
GO:0015108	chloride transmembrane transporter activity	4/1890	121/18639	0.0330578512396694	0.326013380558835	0.998778008962851	0.999999999996313
GO:0030414	peptidase inhibitor activity	7/1890	169/18639	0.0414201183431953	0.408481262327416	0.998801990036742	0.999999999996313
GO:0005539	glycosaminoglycan binding	12/1890	242/18639	0.0495867768595041	0.489020070838253	0.998863685075287	0.999999999996313
GO:0004497	monooxygenase activity	3/1890	106/18639	0.0283018867924528	0.27911051212938	0.999019405017963	0.999999999996313
GO:0015079	potassium ion transmembrane transporter activity	6/1890	160/18639	0.0375	0.369821428571429	0.999268769592333	0.999999999996313
GO:0004252	serine-type endopeptidase activity	7/1890	176/18639	0.0397727272727273	0.392234848484848	0.999289377927195	0.999999999996313
GO:0004222	metalloendopeptidase activity	3/1890	110/18639	0.0272727272727273	0.268961038961039	0.999316884153436	0.999999999996313
GO:0008236	serine-type peptidase activity	8/1890	194/18639	0.0412371134020619	0.406676485027	0.999419652652609	0.999999999996313
GO:0004867	serine-type endopeptidase inhibitor activity	2/1890	95/18639	0.0210526315789474	0.207619047619048	0.999555184694422	0.999999999996313
GO:0017171	serine hydrolase activity	8/1890	198/18639	0.0404040404040404	0.398460798460798	0.999567596485886	0.999999999996313
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/1890	73/18639	0.0136986301369863	0.135094585779517	0.999598755290302	0.999999999996313
GO:0005249	voltage-gated potassium channel activity	2/1890	98/18639	0.0204081632653061	0.201263362487852	0.999668440540266	0.999999999996313
GO:0031406	carboxylic acid binding	7/1890	187/18639	0.0374331550802139	0.369162210338681	0.999692628977878	0.999999999996313
GO:0043177	organic acid binding	7/1890	189/18639	0.037037037037037	0.365255731922399	0.999736635107459	0.999999999996313
GO:0033293	monocarboxylic acid binding	1/1890	79/18639	0.0126582278481013	0.124834237492465	0.999789326075395	0.999999999996313
GO:0022843	voltage-gated monoatomic cation channel activity	4/1890	143/18639	0.027972027972028	0.275857475857476	0.999816770386436	0.999999999996313
GO:0005216	monoatomic ion channel activity	24/1890	448/18639	0.0535714285714286	0.528316326530612	0.999916305523515	0.999999999996313
GO:0005261	monoatomic cation channel activity	16/1890	341/18639	0.0469208211143695	0.462728669180282	0.999928262012399	0.999999999996313
GO:0005125	cytokine activity	8/1890	234/18639	0.0341880341880342	0.337159137159137	0.999972576646976	0.999999999996313
GO:0005267	potassium channel activity	2/1890	124/18639	0.0161290322580645	0.159062980030722	0.99997482700566	0.999999999996313
GO:1901681	sulfur compound binding	10/1890	275/18639	0.0363636363636364	0.358614718614719	0.999986222998467	0.999999999996313
GO:0005179	hormone activity	2/1890	132/18639	0.0151515151515152	0.149422799422799	0.999988718552492	0.999999999996313
GO:0099094	ligand-gated monoatomic cation channel activity	2/1890	136/18639	0.0147058823529412	0.145028011204482	0.999992458114602	0.999999999996313
GO:0022836	gated channel activity	12/1890	318/18639	0.0377358490566038	0.37214734950584	0.999994258480151	0.999999999996313
GO:0008083	growth factor activity	3/1890	162/18639	0.0185185185185185	0.182627865961199	0.999994765157637	0.999999999996313
GO:0005201	extracellular matrix structural constituent	3/1890	168/18639	0.0178571428571429	0.176105442176871	0.999997062536373	0.999999999996313
GO:0015276	ligand-gated monoatomic ion channel activity	2/1890	186/18639	0.010752688172043	0.106041986687148	0.999999953806997	0.999999999996313
GO:0022834	ligand-gated channel activity	2/1890	188/18639	0.0106382978723404	0.104913880445795	0.999999962398548	0.999999999996313
GO:0045182	translation regulator activity	6/1890	356/18639	0.0168539325842697	0.166211878009631	0.999999999978673	0.999999999996313
GO:0030371	translation repressor activity	4/1890	329/18639	0.0121580547112462	0.119901577652338	0.999999999996313	0.999999999996313