ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0031625 ubiquitin protein ligase binding 31/548 302/18639 0.102649006622517 3.49137743510417 1.61113194628894e-09 1.38879573770106e-06 GO:0044389 ubiquitin-like protein ligase binding 31/548 322/18639 0.0962732919254658 3.27452169379335 7.52996762493242e-09 3.24541604634587e-06 GO:0003725 double-stranded RNA binding 13/548 75/18639 0.173333333333333 5.89554744525547 2.54075879437064e-07 7.30044693582497e-05 GO:0140662 ATP-dependent protein folding chaperone 9/548 40/18639 0.225 7.65287408759124 1.86333836183931e-06 0.000389181090767957 GO:0045296 cadherin binding 27/548 334/18639 0.0808383233532934 2.74953560033218 2.25743092092783e-06 0.000389181090767957 GO:0140313 molecular sequestering activity 10/548 55/18639 0.181818181818182 6.18414067684141 3.95462395077536e-06 0.00056814764092806 GO:0051082 unfolded protein binding 14/548 121/18639 0.115702479338843 3.93536224889908 1.29128439873131e-05 0.0015901245024377 GO:0031072 heat shock protein binding 14/548 131/18639 0.106870229007634 3.63495291692205 3.1930592007818e-05 0.00344052128884239 GO:0140311 protein sequestering activity 7/548 33/18639 0.212121212121212 7.21483078964831 4.01549659888158e-05 0.00384595340915102 GO:0044183 protein folding chaperone 10/548 75/18639 0.133333333333333 4.53503649635036 6.62225611020287e-05 0.00570838476699488 GO:0060590 ATPase regulator activity 8/548 49/18639 0.163265306122449 5.55310591389841 8.26926872533241e-05 0.0064800996738514 GO:0023026 MHC class II protein complex binding 6/548 27/18639 0.222222222222222 7.55839416058394 0.000109843719462779 0.00789044051474293 GO:0051087 protein-folding chaperone binding 13/548 134/18639 0.0970149253731343 3.29974670443403 0.000163790450044269 0.0108605667644738 GO:0140297 DNA-binding transcription factor binding 29/548 488/18639 0.0594262295081967 2.02125089745124 0.000284658309836694 0.0175268187913736 GO:0003779 actin binding 27/548 443/18639 0.0609480812641084 2.07301329686444 0.000308169643681906 0.0177094821902536 GO:0042277 peptide binding 18/548 249/18639 0.072289156626506 2.45875472693694 0.000432299761735161 0.0224942743637683 GO:0051020 GTPase binding 21/548 315/18639 0.0666666666666667 2.26751824817518 0.000443622580259932 0.0224942743637683 GO:0019902 phosphatase binding 15/548 190/18639 0.0789473684210526 2.68521897810219 0.000512911338903309 0.0245627541185918 GO:0001618 virus receptor activity 9/548 81/18639 0.111111111111111 3.77919708029197 0.000611312253213761 0.025830638885582 GO:0140272 exogenous protein binding 9/548 82/18639 0.109756097560976 3.73310931102012 0.000669142414811514 0.025830638885582 GO:0023023 MHC protein complex binding 6/548 37/18639 0.162162162162162 5.51558492799369 0.000672464673612175 0.025830638885582 GO:0003743 translation initiation factor activity 7/548 51/18639 0.137254901960784 4.66841992271361 0.000689228420970146 0.025830638885582 GO:0000774 adenyl-nucleotide exchange factor activity 4/548 15/18639 0.266666666666667 9.07007299270073 0.000779114397940989 0.025830638885582 GO:0031386 protein tag activity 4/548 15/18639 0.266666666666667 9.07007299270073 0.000779114397940989 0.025830638885582 GO:0050780 dopamine receptor binding 4/548 15/18639 0.266666666666667 9.07007299270073 0.000779114397940989 0.025830638885582 GO:0141047 molecular tag activity 4/548 15/18639 0.266666666666667 9.07007299270073 0.000779114397940989 0.025830638885582 GO:0005543 phospholipid binding 28/548 497/18639 0.0563380281690141 1.9162126040917 0.000829219322866349 0.0264735946781775 GO:0140104 molecular carrier activity 17/548 249/18639 0.0682730923694779 2.32215724210711 0.00116475785743721 0.0342974980955104 GO:0046966 nuclear thyroid hormone receptor binding 5/548 28/18639 0.178571428571429 6.07370959332638 0.0012102510152843 0.0342974980955104 GO:0097718 disordered domain specific binding 5/548 28/18639 0.178571428571429 6.07370959332638 0.0012102510152843 0.0342974980955104 GO:0042826 histone deacetylase binding 11/548 127/18639 0.0866141732283465 2.94598827518823 0.00132086865554018 0.0342974980955104 GO:0001664 G protein-coupled receptor binding 19/548 297/18639 0.063973063973064 2.17590134925901 0.00132696457635837 0.0342974980955104 GO:0048487 beta-tubulin binding 6/548 42/18639 0.142857142857143 4.85896767466111 0.0013404232063918 0.0342974980955104 GO:0016504 peptidase activator activity 7/548 57/18639 0.12280701754386 4.17700729927007 0.00135280154901085 0.0342974980955104 GO:0072341 modified amino acid binding 9/548 91/18639 0.0989010989010989 3.3639006978423 0.00141843674060436 0.0349340705828846 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 21/548 349/18639 0.0601719197707736 2.04661389161943 0.00162778587496209 0.0376521189605006 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 4/548 18/18639 0.222222222222222 7.55839416058394 0.00162842786562262 0.0376521189605006 GO:0001786 phosphatidylserine binding 7/548 59/18639 0.11864406779661 4.03541383149821 0.00165983819083413 0.0376521189605006 GO:0140658 ATP-dependent chromatin remodeler activity 12/548 158/18639 0.0759493670886076 2.5832486371616 0.00250031707971719 0.055263418531185 GO:0008135 translation factor activity, RNA binding 8/548 83/18639 0.0963855421686747 3.27833963591593 0.00302878584490219 0.0652703349576422 GO:0180051 translation factor activity 8/548 84/18639 0.0952380952380952 3.2393117831074 0.00326358217530668 0.0686148252466916 GO:0019864 IgG binding 3/548 11/18639 0.272727272727273 9.27621101526211 0.00349618461521281 0.0711028585397392 GO:0033691 sialic acid binding 4/548 22/18639 0.181818181818182 6.18414067684141 0.00354689433550903 0.0711028585397392 GO:0005048 signal sequence binding 6/548 51/18639 0.117647058823529 4.00150279089738 0.00368472235131172 0.0721870606097887 GO:0008094 ATP-dependent activity, acting on DNA 14/548 210/18639 0.0666666666666667 2.26751824817518 0.00379885643432203 0.0727692054752354 GO:0004197 cysteine-type endopeptidase activity 8/548 88/18639 0.0909090909090909 3.0920703384207 0.0043471076150175 0.0786616480146173 GO:0031267 small GTPase binding 17/548 283/18639 0.0600706713780919 2.04317015294937 0.00442259394947435 0.0786616480146173 GO:0097110 scaffold protein binding 7/548 70/18639 0.1 3.40127737226277 0.00442527149634799 0.0786616480146173 GO:0016860 intramolecular oxidoreductase activity 6/548 53/18639 0.113207547169811 3.8505026855805 0.00447148579201421 0.0786616480146173 GO:0035325 Toll-like receptor binding 3/548 13/18639 0.230769230769231 7.84910162829871 0.00580040827006561 0.0999990385759311 GO:0016887 ATP hydrolysis activity 22/548 417/18639 0.052757793764988 1.7944389014336 0.00622155741929495 0.105156519518279 GO:0008157 protein phosphatase 1 binding 4/548 26/18639 0.153846153846154 5.23273441886581 0.00660747199254049 0.107464921840942 GO:0050750 low-density lipoprotein particle receptor binding 4/548 26/18639 0.153846153846154 5.23273441886581 0.00660747199254049 0.107464921840942 GO:0016859 cis-trans isomerase activity 5/548 42/18639 0.119047619047619 4.04913972888425 0.00748029555729713 0.112646605682565 GO:0019894 kinesin binding 5/548 42/18639 0.119047619047619 4.04913972888425 0.00748029555729713 0.112646605682565 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 6/548 59/18639 0.101694915254237 3.45892614128418 0.00757410964103463 0.112646605682565 GO:0005044 scavenger receptor activity 4/548 27/18639 0.148148148148148 5.03892944038929 0.00757946998792198 0.112646605682565 GO:0015252 proton channel activity 4/548 27/18639 0.148148148148148 5.03892944038929 0.00757946998792198 0.112646605682565 GO:0003689 DNA clamp loader activity 11/548 160/18639 0.06875 2.33837819343066 0.00778981942921851 0.11381058216926 GO:0017081 chloride channel regulator activity 3/548 15/18639 0.2 6.80255474452555 0.00883375396365992 0.124566719234462 GO:0140776 protein-containing complex destabilizing activity 3/548 15/18639 0.2 6.80255474452555 0.00883375396365992 0.124566719234462 GO:0051015 actin filament binding 13/548 209/18639 0.062200956937799 2.11562707365627 0.00908997029505387 0.124566719234462 GO:0030547 signaling receptor inhibitor activity 5/548 44/18639 0.113636363636364 3.86508792302588 0.00910406416678784 0.124566719234462 GO:0140597 protein carrier chaperone 12/548 188/18639 0.0638297872340425 2.17102810995496 0.00984883379906909 0.127438663587996 GO:0008009 chemokine activity 5/548 45/18639 0.111111111111111 3.77919708029197 0.0100005260272644 0.127438663587996 GO:0042605 peptide antigen binding 5/548 45/18639 0.111111111111111 3.77919708029197 0.0100005260272644 0.127438663587996 GO:0015399 primary active transmembrane transporter activity 11/548 166/18639 0.0662650602409639 2.2538584996922 0.0101271177267126 0.127438663587996 GO:0019903 protein phosphatase binding 10/548 144/18639 0.0694444444444444 2.36199817518248 0.0102010067141204 0.127438663587996 GO:0019955 cytokine binding 10/548 144/18639 0.0694444444444444 2.36199817518248 0.0102010067141204 0.127438663587996 GO:0005159 insulin-like growth factor receptor binding 3/548 16/18639 0.1875 6.3773950729927 0.0106381233717268 0.129155807696176 GO:0005521 lamin binding 3/548 16/18639 0.1875 6.3773950729927 0.0106381233717268 0.129155807696176 GO:0070566 adenylyltransferase activity 4/548 30/18639 0.133333333333333 4.53503649635036 0.011044886107783 0.132231830901513 GO:0070325 lipoprotein particle receptor binding 4/548 31/18639 0.129032258064516 4.38874499646809 0.0123928615839249 0.14633762582662 GO:0051787 misfolded protein binding 3/548 17/18639 0.176470588235294 6.00225418634607 0.0126399116463816 0.147237889718661 GO:0038187 pattern recognition receptor activity 5/548 48/18639 0.104166666666667 3.54299726277372 0.0130489796643081 0.149976272941781 GO:0000510 H3-H4 histone complex chaperone activity 10/548 151/18639 0.0662251655629139 2.25250157103495 0.013909156516844 0.151768264778728 GO:0140584 chromatin extrusion motor activity 10/548 151/18639 0.0662251655629139 2.25250157103495 0.013909156516844 0.151768264778728 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 10/548 151/18639 0.0662251655629139 2.25250157103495 0.013909156516844 0.151768264778728 GO:0140849 ATP-dependent H2AZ histone chaperone activity 10/548 151/18639 0.0662251655629139 2.25250157103495 0.013909156516844 0.151768264778728 GO:0015616 DNA translocase activity 10/548 152/18639 0.0657894736842105 2.23768248175182 0.0145117734369505 0.153476054038726 GO:0140674 ATP-dependent histone chaperone activity 10/548 152/18639 0.0657894736842105 2.23768248175182 0.0145117734369505 0.153476054038726 GO:0003735 structural constituent of ribosome 11/548 175/18639 0.0628571428571429 2.13794577685089 0.0145998102449832 0.153476054038726 GO:0061775 cohesin loader activity 10/548 153/18639 0.065359477124183 2.2230571060541 0.0151336764892359 0.15717143534604 GO:0004386 helicase activity 10/548 155/18639 0.0645161290322581 2.19437249823405 0.0164367484556453 0.168672347247217 GO:0005525 GTP binding 19/548 378/18639 0.0502645502645503 1.7096367744178 0.0168039619152686 0.170411943187783 GO:0015035 protein-disulfide reductase activity 4/548 34/18639 0.117647058823529 4.00150279089738 0.0170507235565901 0.170903764020706 GO:0016853 isomerase activity 11/548 180/18639 0.0611111111111111 2.07855839416058 0.0176539564718506 0.174916212399255 GO:0003924 GTPase activity 17/548 331/18639 0.0513595166163142 1.74687961717423 0.0190230629830444 0.185256184278023 GO:0042379 chemokine receptor binding 6/548 72/18639 0.0833333333333333 2.83439781021898 0.0191273786551555 0.185256184278023 GO:0016505 peptidase activator activity involved in apoptotic process 3/548 20/18639 0.15 5.10191605839416 0.0198566202425358 0.190182296100731 GO:0031491 nucleosome binding 6/548 74/18639 0.0810810810810811 2.75779246399684 0.0216049696563708 0.204653668613095 GO:0019208 phosphatase regulator activity 8/548 117/18639 0.0683760683760684 2.32565974171814 0.0222074057544784 0.208073736525656 GO:0072542 protein phosphatase activator activity 3/548 21/18639 0.142857142857143 4.85896767466111 0.0226710241143071 0.210133578349814 GO:0140713 histone chaperone activity 10/548 164/18639 0.0609756097560976 2.0739496172334 0.0233467372521187 0.214094547992833 GO:0004407 histone deacetylase activity 3/548 22/18639 0.136363636363636 4.63810550763105 0.0256906235530647 0.224464590384503 GO:0033558 protein lysine deacetylase activity 3/548 22/18639 0.136363636363636 4.63810550763105 0.0256906235530647 0.224464590384503 GO:0061133 endopeptidase activator activity 3/548 22/18639 0.136363636363636 4.63810550763105 0.0256906235530647 0.224464590384503 GO:0003724 RNA helicase activity 6/548 77/18639 0.0779220779220779 2.6503460043606 0.0257135677189262 0.224464590384503 GO:0004601 peroxidase activity 5/548 57/18639 0.087719298245614 2.98357664233577 0.0257795759258304 0.224464590384503 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 4/548 39/18639 0.102564102564103 3.4884896125772 0.0269772868033634 0.232544212244992 GO:0019001 guanyl nucleotide binding 19/548 400/18639 0.0475 1.61560675182482 0.0281273352776719 0.234176711286937 GO:0032561 guanyl ribonucleotide binding 19/548 400/18639 0.0475 1.61560675182482 0.0281273352776719 0.234176711286937 GO:0008186 ATP-dependent activity, acting on RNA 6/548 79/18639 0.0759493670886076 2.5832486371616 0.0287232262612377 0.234176711286937 GO:0046332 SMAD binding 6/548 79/18639 0.0759493670886076 2.5832486371616 0.0287232262612377 0.234176711286937 GO:0005158 insulin receptor binding 3/548 23/18639 0.130434782608696 4.4364487464297 0.0289149465461865 0.234176711286937 GO:0004177 aminopeptidase activity 4/548 40/18639 0.1 3.40127737226277 0.0293003304454683 0.234176711286937 GO:0015036 disulfide oxidoreductase activity 4/548 40/18639 0.1 3.40127737226277 0.0293003304454683 0.234176711286937 GO:0061650 ubiquitin-like protein conjugating enzyme activity 4/548 41/18639 0.0975609756097561 3.31831938757344 0.0317382733722579 0.234176711286937 GO:0005528 FK506 binding 2/548 10/18639 0.2 6.80255474452555 0.0332068427478995 0.234176711286937 GO:0008140 cAMP response element binding protein binding 2/548 10/18639 0.2 6.80255474452555 0.0332068427478995 0.234176711286937 GO:0008239 dipeptidyl-peptidase activity 2/548 10/18639 0.2 6.80255474452555 0.0332068427478995 0.234176711286937 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/548 10/18639 0.2 6.80255474452555 0.0332068427478995 0.234176711286937 GO:0030957 Tat protein binding 2/548 10/18639 0.2 6.80255474452555 0.0332068427478995 0.234176711286937 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 2/548 10/18639 0.2 6.80255474452555 0.0332068427478995 0.234176711286937 GO:0031720 haptoglobin binding 2/548 10/18639 0.2 6.80255474452555 0.0332068427478995 0.234176711286937 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 2/548 10/18639 0.2 6.80255474452555 0.0332068427478995 0.234176711286937 GO:0043422 protein kinase B binding 2/548 10/18639 0.2 6.80255474452555 0.0332068427478995 0.234176711286937 GO:0051880 G-quadruplex DNA binding 2/548 10/18639 0.2 6.80255474452555 0.0332068427478995 0.234176711286937 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 2/548 10/18639 0.2 6.80255474452555 0.0332068427478995 0.234176711286937 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 2/548 10/18639 0.2 6.80255474452555 0.0332068427478995 0.234176711286937 GO:1905394 retromer complex binding 2/548 10/18639 0.2 6.80255474452555 0.0332068427478995 0.234176711286937 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 2/548 10/18639 0.2 6.80255474452555 0.0332068427478995 0.234176711286937 GO:0005126 cytokine receptor binding 14/548 275/18639 0.0509090909090909 1.73155938951559 0.0334150063669295 0.234176711286937 GO:0051879 Hsp90 protein binding 4/548 42/18639 0.0952380952380952 3.2393117831074 0.0342917447212011 0.238382935078027 GO:0061134 peptidase regulator activity 12/548 226/18639 0.0530973451327434 1.80598798527227 0.035619621298811 0.243372624632747 GO:0019211 phosphatase activator activity 3/548 25/18639 0.12 4.08153284671533 0.0359731297077717 0.243372624632747 GO:0035591 signaling adaptor activity 8/548 129/18639 0.062015503875969 2.10931930062808 0.0367973520122917 0.243372624632747 GO:0048156 tau protein binding 4/548 43/18639 0.0930232558139535 3.16397895094212 0.0369611970136494 0.243372624632747 GO:0004860 protein kinase inhibitor activity 6/548 84/18639 0.0714285714285714 2.42948383733055 0.0372337746445513 0.243372624632747 GO:0051117 ATPase binding 6/548 84/18639 0.0714285714285714 2.42948383733055 0.0372337746445513 0.243372624632747 GO:0019888 protein phosphatase regulator activity 7/548 107/18639 0.0654205607476635 2.2251347295177 0.0384939722166137 0.243372624632747 GO:0019887 protein kinase regulator activity 13/548 255/18639 0.0509803921568627 1.7339845427222 0.0390387557349231 0.243372624632747 GO:0003714 transcription corepressor activity 11/548 204/18639 0.053921568627451 1.83402211249463 0.0392079064843574 0.243372624632747 GO:0019865 immunoglobulin binding 3/548 26/18639 0.115384615384615 3.92455081414935 0.0398034328880192 0.243372624632747 GO:0008199 ferric iron binding 2/548 11/18639 0.181818181818182 6.18414067684141 0.0398092112218299 0.243372624632747 GO:0010854 adenylate cyclase regulator activity 2/548 11/18639 0.181818181818182 6.18414067684141 0.0398092112218299 0.243372624632747 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 2/548 11/18639 0.181818181818182 6.18414067684141 0.0398092112218299 0.243372624632747 GO:0034511 U3 snoRNA binding 2/548 11/18639 0.181818181818182 6.18414067684141 0.0398092112218299 0.243372624632747 GO:0050786 RAGE receptor binding 2/548 11/18639 0.181818181818182 6.18414067684141 0.0398092112218299 0.243372624632747 GO:0050998 nitric-oxide synthase binding 2/548 11/18639 0.181818181818182 6.18414067684141 0.0398092112218299 0.243372624632747 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/548 11/18639 0.181818181818182 6.18414067684141 0.0398092112218299 0.243372624632747 GO:0140097 catalytic activity, acting on DNA 16/548 336/18639 0.0476190476190476 1.6196558915537 0.0407151025803646 0.247157876227284 GO:0140375 immune receptor activity 9/548 156/18639 0.0576923076923077 1.96227540707468 0.0412100351601039 0.24841293921685 GO:0035091 phosphatidylinositol binding 14/548 284/18639 0.0492957746478873 1.67668602858024 0.0419483435038662 0.250480290307668 GO:0038024 cargo receptor activity 5/548 65/18639 0.0769230769230769 2.6163672094329 0.0421341555621947 0.250480290307668 GO:0001671 ATPase activator activity 3/548 27/18639 0.111111111111111 3.77919708029197 0.0438314282505314 0.254963244873315 GO:0008320 protein transmembrane transporter activity 3/548 27/18639 0.111111111111111 3.77919708029197 0.0438314282505314 0.254963244873315 GO:0005025 transforming growth factor beta receptor activity, type I 2/548 12/18639 0.166666666666667 5.66879562043796 0.0468589443880404 0.254963244873315 GO:0005026 transforming growth factor beta receptor activity, type II 2/548 12/18639 0.166666666666667 5.66879562043796 0.0468589443880404 0.254963244873315 GO:0005527 macrolide binding 2/548 12/18639 0.166666666666667 5.66879562043796 0.0468589443880404 0.254963244873315 GO:0016361 activin receptor activity, type I 2/548 12/18639 0.166666666666667 5.66879562043796 0.0468589443880404 0.254963244873315 GO:0016362 activin receptor activity, type II 2/548 12/18639 0.166666666666667 5.66879562043796 0.0468589443880404 0.254963244873315 GO:0017002 activin receptor activity 2/548 12/18639 0.166666666666667 5.66879562043796 0.0468589443880404 0.254963244873315 GO:0031543 peptidyl-proline dioxygenase activity 2/548 12/18639 0.166666666666667 5.66879562043796 0.0468589443880404 0.254963244873315 GO:0035259 nuclear glucocorticoid receptor binding 2/548 12/18639 0.166666666666667 5.66879562043796 0.0468589443880404 0.254963244873315 GO:0070008 serine-type exopeptidase activity 2/548 12/18639 0.166666666666667 5.66879562043796 0.0468589443880404 0.254963244873315 GO:0097677 STAT family protein binding 2/548 12/18639 0.166666666666667 5.66879562043796 0.0468589443880404 0.254963244873315 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/548 12/18639 0.166666666666667 5.66879562043796 0.0468589443880404 0.254963244873315 GO:0015078 proton transmembrane transporter activity 10/548 185/18639 0.0540540540540541 1.83852830933123 0.0471844831816176 0.254963244873315 GO:0005200 structural constituent of cytoskeleton 7/548 112/18639 0.0625 2.12579835766423 0.0473249642456269 0.254963244873315 GO:0046875 ephrin receptor binding 3/548 28/18639 0.107142857142857 3.64422575599583 0.0480542788625918 0.255696224565149 GO:0051019 mitogen-activated protein kinase binding 3/548 28/18639 0.107142857142857 3.64422575599583 0.0480542788625918 0.255696224565149 GO:0005178 integrin binding 9/548 161/18639 0.0559006211180124 1.9013351770413 0.048650467315588 0.257280385435809 GO:0019210 kinase inhibitor activity 6/548 90/18639 0.0666666666666667 2.26751824817518 0.0493811397416917 0.257407584661023 GO:0016922 nuclear receptor binding 8/548 137/18639 0.0583941605839416 1.98614737066439 0.0494758029016846 0.257407584661023 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 5/548 68/18639 0.0735294117647059 2.50093924431086 0.0495703701319372 0.257407584661023 GO:0031406 carboxylic acid binding 10/548 187/18639 0.053475935828877 1.81886490495335 0.0500845536268496 0.258039060930292 GO:0003785 actin monomer binding 3/548 29/18639 0.103448275862069 3.51856279889252 0.0524687908269997 0.258039060930292 GO:0106222 lncRNA binding 3/548 29/18639 0.103448275862069 3.51856279889252 0.0524687908269997 0.258039060930292 GO:0043177 organic acid binding 10/548 189/18639 0.0529100529100529 1.79961765728189 0.0531013742051196 0.258039060930292 GO:0017124 SH3 domain binding 7/548 115/18639 0.0608695652173913 2.07034274833386 0.0531960336238983 0.258039060930292 GO:0005542 folic acid binding 2/548 13/18639 0.153846153846154 5.23273441886581 0.0543241327731268 0.258039060930292 GO:0070123 transforming growth factor beta receptor activity, type III 2/548 13/18639 0.153846153846154 5.23273441886581 0.0543241327731268 0.258039060930292 GO:0030695 GTPase regulator activity 21/548 489/18639 0.0429447852760736 1.46067126416193 0.0543679443458989 0.258039060930292 GO:0004674 protein serine/threonine kinase activity 19/548 433/18639 0.0438799076212471 1.49247736889129 0.0547442447168148 0.258039060930292 GO:0060589 nucleoside-triphosphatase regulator activity 21/548 490/18639 0.0428571428571429 1.45769030239833 0.0553150082507144 0.258039060930292 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 12/548 243/18639 0.0493827160493827 1.67964314679643 0.0561269415527068 0.258039060930292 GO:0051219 phosphoprotein binding 6/548 93/18639 0.0645161290322581 2.19437249823405 0.0562692079620789 0.258039060930292 GO:1990782 protein tyrosine kinase binding 7/548 117/18639 0.0598290598290598 2.03495227400337 0.0573526793887448 0.258039060930292 GO:0048020 CCR chemokine receptor binding 4/548 50/18639 0.08 2.72102189781022 0.058897781226443 0.258039060930292 GO:0004676 3-phosphoinositide-dependent protein kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:0004711 ribosomal protein S6 kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:0035175 histone H3S10 kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:0035979 histone H2AXS139 kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:0044022 histone H3S28 kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:0044023 histone H4S1 kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:0044024 histone H2AS1 kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:0044025 histone H2BS14 kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:0072354 histone H3T3 kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:0072371 histone H2AS121 kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:0072518 Rho-dependent protein serine/threonine kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:0140823 histone H2BS36 kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:0140855 histone H3S57 kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:0140995 histone H2A kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:0140997 histone H4 kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:0140998 histone H2B kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:1990244 histone H2AT120 kinase activity 12/548 245/18639 0.0489795918367347 1.66593177416952 0.0589718039481062 0.258039060930292 GO:0022853 active monoatomic ion transmembrane transporter activity 7/548 118/18639 0.0593220338983051 2.0177069157491 0.0595043111743323 0.258909614410227 GO:0004677 DNA-dependent protein kinase activity 12/548 246/18639 0.0487804878048781 1.65915969378672 0.0604296741968958 0.258909614410227 GO:0140857 histone H3T45 kinase activity 12/548 246/18639 0.0487804878048781 1.65915969378672 0.0604296741968958 0.258909614410227 GO:0035402 histone H3T11 kinase activity 12/548 247/18639 0.048582995951417 1.65244244806289 0.0619113119850987 0.258909614410227 GO:0035403 histone H3T6 kinase activity 12/548 247/18639 0.048582995951417 1.65244244806289 0.0619113119850987 0.258909614410227 GO:0005344 oxygen carrier activity 2/548 14/18639 0.142857142857143 4.85896767466111 0.0621743505602286 0.258909614410227 GO:0005545 1-phosphatidylinositol binding 2/548 14/18639 0.142857142857143 4.85896767466111 0.0621743505602286 0.258909614410227 GO:0019763 immunoglobulin receptor activity 2/548 14/18639 0.142857142857143 4.85896767466111 0.0621743505602286 0.258909614410227 GO:0032036 myosin heavy chain binding 2/548 14/18639 0.142857142857143 4.85896767466111 0.0621743505602286 0.258909614410227 GO:0098821 BMP receptor activity 2/548 14/18639 0.142857142857143 4.85896767466111 0.0621743505602286 0.258909614410227 GO:0004679 AMP-activated protein kinase activity 12/548 248/18639 0.0483870967741935 1.64577937367554 0.0634168170300101 0.262813924422446 GO:0022884 macromolecule transmembrane transporter activity 3/548 32/18639 0.09375 3.18869753649635 0.0668256938968675 0.275616019804305 GO:0106310 protein serine kinase activity 16/548 361/18639 0.0443213296398892 1.50749135612755 0.0684973344085968 0.281165248858145 GO:0042626 ATPase-coupled transmembrane transporter activity 6/548 98/18639 0.0612244897959184 2.0824147177119 0.0689719614174146 0.281771709676831 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/548 15/18639 0.133333333333333 4.53503649635036 0.07038059619047 0.283495672505538 GO:0141050 histone H3K deacetylase activity 2/548 15/18639 0.133333333333333 4.53503649635036 0.07038059619047 0.283495672505538 GO:0141051 histone H4K deacetylase activity 2/548 15/18639 0.133333333333333 4.53503649635036 0.07038059619047 0.283495672505538 GO:0016829 lyase activity 10/548 200/18639 0.05 1.70063868613139 0.0718332169945979 0.28720925877778 GO:0071889 14-3-3 protein binding 3/548 33/18639 0.0909090909090909 3.0920703384207 0.071968909392112 0.28720925877778 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 4/548 54/18639 0.0740740740740741 2.51946472019465 0.0739461403267241 0.293739967565144 GO:0005024 transforming growth factor beta receptor activity 2/548 16/18639 0.125 4.25159671532847 0.0789152351645762 0.30504454130881 GO:0016722 oxidoreductase activity, acting on metal ions 2/548 16/18639 0.125 4.25159671532847 0.0789152351645762 0.30504454130881 GO:0022858 alanine transmembrane transporter activity 2/548 16/18639 0.125 4.25159671532847 0.0789152351645762 0.30504454130881 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/548 16/18639 0.125 4.25159671532847 0.0789152351645762 0.30504454130881 GO:0034450 ubiquitin-ubiquitin ligase activity 2/548 16/18639 0.125 4.25159671532847 0.0789152351645762 0.30504454130881 GO:0070411 I-SMAD binding 2/548 16/18639 0.125 4.25159671532847 0.0789152351645762 0.30504454130881 GO:0019207 kinase regulator activity 13/548 287/18639 0.0452961672473868 1.54064828708767 0.0824766498153092 0.317387822057127 GO:0005506 iron ion binding 8/548 154/18639 0.051948051948052 1.7668973362404 0.0849400447976089 0.325414749402395 GO:0004550 nucleoside diphosphate kinase activity 2/548 17/18639 0.117647058823529 4.00150279089738 0.087751944967002 0.325675029022163 GO:0005092 GDP-dissociation inhibitor activity 2/548 17/18639 0.117647058823529 4.00150279089738 0.087751944967002 0.325675029022163 GO:0008429 phosphatidylethanolamine binding 2/548 17/18639 0.117647058823529 4.00150279089738 0.087751944967002 0.325675029022163 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/548 17/18639 0.117647058823529 4.00150279089738 0.087751944967002 0.325675029022163 GO:0045236 CXCR chemokine receptor binding 2/548 17/18639 0.117647058823529 4.00150279089738 0.087751944967002 0.325675029022163 GO:0070403 NAD+ binding 2/548 17/18639 0.117647058823529 4.00150279089738 0.087751944967002 0.325675029022163 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 3/548 36/18639 0.0833333333333333 2.83439781021898 0.0884083025419793 0.325675029022163 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 3/548 36/18639 0.0833333333333333 2.83439781021898 0.0884083025419793 0.325675029022163 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 3/548 36/18639 0.0833333333333333 2.83439781021898 0.0884083025419793 0.325675029022163 GO:0019213 deacetylase activity 3/548 37/18639 0.0810810810810811 2.75779246399684 0.0942085226094969 0.345033887092468 GO:1901981 phosphatidylinositol phosphate binding 9/548 185/18639 0.0486486486486487 1.65467547839811 0.0963333847352894 0.345033887092468 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/548 18/18639 0.111111111111111 3.77919708029197 0.0968656620375607 0.345033887092468 GO:0004706 JUN kinase kinase kinase activity 2/548 18/18639 0.111111111111111 3.77919708029197 0.0968656620375607 0.345033887092468 GO:0008409 5'-3' exonuclease activity 2/548 18/18639 0.111111111111111 3.77919708029197 0.0968656620375607 0.345033887092468 GO:0032393 MHC class I receptor activity 2/548 18/18639 0.111111111111111 3.77919708029197 0.0968656620375607 0.345033887092468 GO:0034185 apolipoprotein binding 2/548 18/18639 0.111111111111111 3.77919708029197 0.0968656620375607 0.345033887092468 GO:0035615 clathrin adaptor activity 2/548 18/18639 0.111111111111111 3.77919708029197 0.0968656620375607 0.345033887092468 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 3/548 38/18639 0.0789473684210526 2.68521897810219 0.10016053887363 0.355301993864481 GO:0141003 histone H2AX kinase activity 15/548 354/18639 0.0423728813559322 1.44121922553507 0.101100931138716 0.356131185679701 GO:0008234 cysteine-type peptidase activity 9/548 187/18639 0.0481283422459893 1.63697841445802 0.10122058061662 0.356131185679701 GO:0015026 coreceptor activity 4/548 61/18639 0.0655737704918033 2.23034581787723 0.104427056621439 0.365919198405206 GO:0015631 tubulin binding 16/548 385/18639 0.0415584415584416 1.41351786899232 0.105066392951144 0.366668950299133 GO:0003756 protein disulfide isomerase activity 2/548 19/18639 0.105263157894737 3.58029197080292 0.106232530718102 0.367135656094175 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/548 19/18639 0.105263157894737 3.58029197080292 0.106232530718102 0.367135656094175 GO:0140996 histone H3 kinase activity 15/548 357/18639 0.0420168067226891 1.42910813960621 0.10647785849599 0.367135656094175 GO:0004857 enzyme inhibitor activity 17/548 416/18639 0.0408653846153846 1.38994508001123 0.108516803790898 0.372675238516947 GO:0016209 antioxidant activity 5/548 86/18639 0.0581395348837209 1.97748684433882 0.109181678607482 0.373470662538292 GO:0035173 histone kinase activity 15/548 360/18639 0.0416666666666667 1.41719890510949 0.112025476256386 0.380537927354665 GO:0004532 RNA exonuclease activity 3/548 40/18639 0.075 2.55095802919708 0.112499046950712 0.380537927354665 GO:0043022 ribosome binding 6/548 112/18639 0.0535714285714286 1.82211287799791 0.112572124681484 0.380537927354665 GO:0010851 cyclase regulator activity 2/548 20/18639 0.1 3.40127737226277 0.115829854104276 0.388503246061814 GO:0043024 ribosomal small subunit binding 2/548 20/18639 0.1 3.40127737226277 0.115829854104276 0.388503246061814 GO:0001530 lipopolysaccharide binding 3/548 41/18639 0.0731707317073171 2.48873954068008 0.11887489749638 0.391107487182745 GO:0008137 NADH dehydrogenase (ubiquinone) activity 3/548 41/18639 0.0731707317073171 2.48873954068008 0.11887489749638 0.391107487182745 GO:0042169 SH2 domain binding 3/548 41/18639 0.0731707317073171 2.48873954068008 0.11887489749638 0.391107487182745 GO:0042287 MHC protein binding 3/548 41/18639 0.0731707317073171 2.48873954068008 0.11887489749638 0.391107487182745 GO:0140318 protein transporter activity 3/548 41/18639 0.0731707317073171 2.48873954068008 0.11887489749638 0.391107487182745 GO:0160215 deacylase activity 4/548 65/18639 0.0615384615384615 2.09309376754632 0.124029501900444 0.402595807752405 GO:0030246 carbohydrate binding 12/548 280/18639 0.0428571428571429 1.45769030239833 0.12450613717827 0.402595807752405 GO:0008373 sialyltransferase activity 2/548 21/18639 0.0952380952380952 3.2393117831074 0.125636046734799 0.402595807752405 GO:0010314 phosphatidylinositol-5-phosphate binding 2/548 21/18639 0.0952380952380952 3.2393117831074 0.125636046734799 0.402595807752405 GO:0051428 peptide hormone receptor binding 2/548 21/18639 0.0952380952380952 3.2393117831074 0.125636046734799 0.402595807752405 GO:0070182 DNA polymerase binding 2/548 21/18639 0.0952380952380952 3.2393117831074 0.125636046734799 0.402595807752405 GO:0140312 cargo adaptor activity 2/548 21/18639 0.0952380952380952 3.2393117831074 0.125636046734799 0.402595807752405 GO:0008200 ion channel inhibitor activity 3/548 43/18639 0.0697674418604651 2.37298421320659 0.132012801127455 0.421463091006911 GO:0031683 G-protein beta/gamma-subunit complex binding 2/548 22/18639 0.0909090909090909 3.0920703384207 0.135630589052973 0.431415379201707 GO:0003954 NADH dehydrogenase activity 3/548 44/18639 0.0681818181818182 2.31905275381553 0.138763963871049 0.438148486655107 GO:0016248 channel inhibitor activity 3/548 44/18639 0.0681818181818182 2.31905275381553 0.138763963871049 0.438148486655107 GO:0030145 manganese ion binding 4/548 68/18639 0.0588235294117647 2.00075139544869 0.139674231274269 0.439413092548978 GO:0141110 transporter inhibitor activity 3/548 45/18639 0.0666666666666667 2.26751824817518 0.145629318678361 0.455342079143998 GO:0043274 phospholipase binding 2/548 23/18639 0.0869565217391304 2.9576324976198 0.145793983577429 0.455342079143998 GO:0043021 ribonucleoprotein complex binding 8/548 177/18639 0.0451977401129944 1.53730050723741 0.151494966103786 0.471439208597343 GO:0004896 cytokine receptor activity 5/548 96/18639 0.0520833333333333 1.77149863138686 0.152556435164788 0.473034701841897 GO:0004622 lysophospholipase activity 2/548 24/18639 0.0833333333333333 2.83439781021898 0.156107712721247 0.473819888611673 GO:0019957 C-C chemokine binding 2/548 24/18639 0.0833333333333333 2.83439781021898 0.156107712721247 0.473819888611673 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/548 24/18639 0.0833333333333333 2.83439781021898 0.156107712721247 0.473819888611673 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/548 24/18639 0.0833333333333333 2.83439781021898 0.156107712721247 0.473819888611673 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/548 24/18639 0.0833333333333333 2.83439781021898 0.156107712721247 0.473819888611673 GO:0048027 mRNA 5'-UTR binding 2/548 24/18639 0.0833333333333333 2.83439781021898 0.156107712721247 0.473819888611673 GO:0061630 ubiquitin protein ligase activity 14/548 353/18639 0.0396600566572238 1.34894853290875 0.159420913175105 0.481275636055994 GO:0001784 phosphotyrosine residue binding 3/548 47/18639 0.0638297872340425 2.17102810995496 0.159680779480295 0.481275636055994 GO:0004709 MAP kinase kinase kinase activity 2/548 25/18639 0.08 2.72102189781022 0.16655419820068 0.495965131372508 GO:0008139 nuclear localization sequence binding 2/548 25/18639 0.08 2.72102189781022 0.16655419820068 0.495965131372508 GO:0017025 TBP-class protein binding 2/548 25/18639 0.08 2.72102189781022 0.16655419820068 0.495965131372508 GO:0032266 phosphatidylinositol-3-phosphate binding 3/548 48/18639 0.0625 2.12579835766423 0.166856018675206 0.495965131372508 GO:0035254 glutamate receptor binding 3/548 49/18639 0.0612244897959184 2.0824147177119 0.174123735397118 0.515789209320674 GO:0005160 transforming growth factor beta receptor binding 2/548 26/18639 0.0769230769230769 2.6163672094329 0.177116761976735 0.515792732513329 GO:0008143 poly(A) binding 2/548 26/18639 0.0769230769230769 2.6163672094329 0.177116761976735 0.515792732513329 GO:0008198 ferrous iron binding 2/548 26/18639 0.0769230769230769 2.6163672094329 0.177116761976735 0.515792732513329 GO:0030507 spectrin binding 2/548 26/18639 0.0769230769230769 2.6163672094329 0.177116761976735 0.515792732513329 GO:0034237 protein kinase A regulatory subunit binding 2/548 26/18639 0.0769230769230769 2.6163672094329 0.177116761976735 0.515792732513329 GO:0019003 GDP binding 4/548 75/18639 0.0533333333333333 1.81401459854015 0.178941507393762 0.519352119102434 GO:0008238 exopeptidase activity 5/548 102/18639 0.0490196078431373 1.66729282954058 0.181529045662128 0.525094085103203 GO:0017022 myosin binding 4/548 76/18639 0.0526315789473684 1.79014598540146 0.184830809234166 0.532856714246993 GO:0035255 ionotropic glutamate receptor binding 2/548 27/18639 0.0740740740740741 2.51946472019465 0.187779588674831 0.539553351459015 GO:0016830 carbon-carbon lyase activity 3/548 51/18639 0.0588235294117647 2.00075139544869 0.188915266509702 0.541013155253697 GO:0030159 signaling receptor complex adaptor activity 3/548 52/18639 0.0576923076923077 1.96227540707468 0.196428544349608 0.560666904732987 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/548 28/18639 0.0714285714285714 2.42948383733055 0.198527689429619 0.564788344185912 GO:0046982 protein heterodimerization activity 14/548 369/18639 0.037940379403794 1.29045753961189 0.200019644389372 0.567160965340916 GO:0008083 growth factor activity 7/548 162/18639 0.0432098765432099 1.46968775344688 0.200679312251379 0.567165793969472 GO:0016835 carbon-oxygen lyase activity 4/548 79/18639 0.0506329113924051 1.72216575810773 0.202862539535944 0.571462447973804 GO:0061659 ubiquitin-like protein ligase activity 14/548 372/18639 0.0376344086021505 1.28005062396986 0.208124023508481 0.581096213722756 GO:0003712 transcription coregulator activity 18/548 495/18639 0.0363636363636364 1.23682813536828 0.208906179923936 0.581096213722756 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/548 29/18639 0.0689655172413793 2.34570853259502 0.209346867103887 0.581096213722756 GO:0017069 snRNA binding 3/548 54/18639 0.0555555555555556 1.88959854014599 0.211664246038888 0.581096213722756 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/548 54/18639 0.0555555555555556 1.88959854014599 0.211664246038888 0.581096213722756 GO:0051287 NAD binding 3/548 54/18639 0.0555555555555556 1.88959854014599 0.211664246038888 0.581096213722756 GO:0016779 nucleotidyltransferase activity 6/548 136/18639 0.0441176470588235 1.50056354658652 0.21167541891989 0.581096213722756 GO:0044325 transmembrane transporter binding 6/548 136/18639 0.0441176470588235 1.50056354658652 0.21167541891989 0.581096213722756 GO:0030971 receptor tyrosine kinase binding 4/548 81/18639 0.0493827160493827 1.67964314679643 0.215161250718957 0.588790470221399 GO:0001965 G-protein alpha-subunit binding 2/548 30/18639 0.0666666666666667 2.26751824817518 0.220223682832242 0.595087193107814 GO:0001968 fibronectin binding 2/548 30/18639 0.0666666666666667 2.26751824817518 0.220223682832242 0.595087193107814 GO:0048019 receptor antagonist activity 2/548 30/18639 0.0666666666666667 2.26751824817518 0.220223682832242 0.595087193107814 GO:0051721 protein phosphatase 2A binding 2/548 30/18639 0.0666666666666667 2.26751824817518 0.220223682832242 0.595087193107814 GO:0001540 amyloid-beta binding 4/548 83/18639 0.0481927710843374 1.63916981795796 0.227658089849077 0.613253979530952 GO:0008327 methyl-CpG binding 2/548 31/18639 0.0645161290322581 2.19437249823405 0.231145423841947 0.61878060668248 GO:0070273 phosphatidylinositol-4-phosphate binding 2/548 31/18639 0.0645161290322581 2.19437249823405 0.231145423841947 0.61878060668248 GO:0004527 exonuclease activity 4/548 84/18639 0.0476190476190476 1.6196558915537 0.23397442718493 0.624414725180834 GO:0005085 guanyl-nucleotide exchange factor activity 9/548 230/18639 0.0391304347826087 1.33093462392891 0.237126828725683 0.626655592868948 GO:0030515 snoRNA binding 2/548 32/18639 0.0625 2.12579835766423 0.242100072504952 0.626655592868948 GO:0031369 translation initiation factor binding 2/548 32/18639 0.0625 2.12579835766423 0.242100072504952 0.626655592868948 GO:0043425 bHLH transcription factor binding 2/548 32/18639 0.0625 2.12579835766423 0.242100072504952 0.626655592868948 GO:0051059 NF-kappaB binding 2/548 32/18639 0.0625 2.12579835766423 0.242100072504952 0.626655592868948 GO:0070717 poly-purine tract binding 2/548 32/18639 0.0625 2.12579835766423 0.242100072504952 0.626655592868948 GO:0140142 nucleocytoplasmic carrier activity 2/548 32/18639 0.0625 2.12579835766423 0.242100072504952 0.626655592868948 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 3/548 58/18639 0.0517241379310345 1.75928139944626 0.242831910616678 0.626655592868948 GO:0019787 ubiquitin-like protein transferase activity 17/548 479/18639 0.0354906054279749 1.20713393170078 0.246522041823661 0.626655592868948 GO:0045309 protein phosphorylated amino acid binding 3/548 59/18639 0.0508474576271186 1.72946307064209 0.250740607841674 0.626655592868948 GO:0070063 RNA polymerase binding 3/548 59/18639 0.0508474576271186 1.72946307064209 0.250740607841674 0.626655592868948 GO:0070888 E-box binding 3/548 59/18639 0.0508474576271186 1.72946307064209 0.250740607841674 0.626655592868948 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/548 33/18639 0.0606060606060606 2.0613802256138 0.253076276576748 0.626655592868948 GO:0019956 chemokine binding 2/548 33/18639 0.0606060606060606 2.0613802256138 0.253076276576748 0.626655592868948 GO:0140416 transcription regulator inhibitor activity 2/548 33/18639 0.0606060606060606 2.0613802256138 0.253076276576748 0.626655592868948 GO:0009055 electron transfer activity 5/548 116/18639 0.0431034482758621 1.46606783287189 0.255738003780735 0.626655592868948 GO:0004721 phosphoprotein phosphatase activity 7/548 175/18639 0.04 1.36051094890511 0.256753529953454 0.626655592868948 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/548 10/18639 0.1 3.40127737226277 0.258061545308867 0.626655592868948 GO:0004955 prostaglandin receptor activity 1/548 10/18639 0.1 3.40127737226277 0.258061545308867 0.626655592868948 GO:0005031 tumor necrosis factor receptor activity 1/548 10/18639 0.1 3.40127737226277 0.258061545308867 0.626655592868948 GO:0005522 profilin binding 1/548 10/18639 0.1 3.40127737226277 0.258061545308867 0.626655592868948 GO:0015187 glycine transmembrane transporter activity 1/548 10/18639 0.1 3.40127737226277 0.258061545308867 0.626655592868948 GO:0015203 polyamine transmembrane transporter activity 1/548 10/18639 0.1 3.40127737226277 0.258061545308867 0.626655592868948 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/548 10/18639 0.1 3.40127737226277 0.258061545308867 0.626655592868948 GO:0042975 peroxisome proliferator activated receptor binding 1/548 10/18639 0.1 3.40127737226277 0.258061545308867 0.626655592868948 GO:0140940 histone H2A methyltransferase activity 1/548 10/18639 0.1 3.40127737226277 0.258061545308867 0.626655592868948 GO:1990259 histone H2AQ104 methyltransferase activity 1/548 10/18639 0.1 3.40127737226277 0.258061545308867 0.626655592868948 GO:1990763 arrestin family protein binding 1/548 10/18639 0.1 3.40127737226277 0.258061545308867 0.626655592868948 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/548 60/18639 0.05 1.70063868613139 0.258686680691858 0.626655592868948 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3/548 60/18639 0.05 1.70063868613139 0.258686680691858 0.626655592868948 GO:0016831 carboxy-lyase activity 2/548 34/18639 0.0588235294117647 2.00075139544869 0.264063320579203 0.626655592868948 GO:0019825 oxygen binding 2/548 34/18639 0.0588235294117647 2.00075139544869 0.264063320579203 0.626655592868948 GO:0051427 hormone receptor binding 2/548 34/18639 0.0588235294117647 2.00075139544869 0.264063320579203 0.626655592868948 GO:0003727 single-stranded RNA binding 4/548 89/18639 0.0449438202247191 1.52866398753383 0.266134404559919 0.626655592868948 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 4/548 89/18639 0.0449438202247191 1.52866398753383 0.266134404559919 0.626655592868948 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 4/548 89/18639 0.0449438202247191 1.52866398753383 0.266134404559919 0.626655592868948 GO:0016836 hydro-lyase activity 3/548 61/18639 0.0491803278688525 1.67275936340792 0.266665626764466 0.626655592868948 GO:0019905 syntaxin binding 3/548 61/18639 0.0491803278688525 1.67275936340792 0.266665626764466 0.626655592868948 GO:0140793 histone H2AXY142 phosphatase activity 4/548 90/18639 0.0444444444444444 1.51167883211679 0.272664670726494 0.626655592868948 GO:0004518 nuclease activity 8/548 209/18639 0.0382775119617225 1.30192435301924 0.273643908476542 0.626655592868948 GO:0000175 3'-5'-RNA exonuclease activity 2/548 35/18639 0.0571428571428571 1.94358706986444 0.275051098286027 0.626655592868948 GO:0061631 ubiquitin conjugating enzyme activity 2/548 35/18639 0.0571428571428571 1.94358706986444 0.275051098286027 0.626655592868948 GO:0005096 GTPase activator activity 10/548 271/18639 0.03690036900369 1.25508390120398 0.276459559598924 0.626655592868948 GO:0032182 ubiquitin-like protein binding 5/548 120/18639 0.0416666666666667 1.41719890510949 0.278196311950745 0.626655592868948 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0004016 adenylate cyclase activity 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0004954 prostanoid receptor activity 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0005114 type II transforming growth factor beta receptor binding 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0008432 JUN kinase binding 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0015173 aromatic amino acid transmembrane transporter activity 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0031731 CCR6 chemokine receptor binding 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0032050 clathrin heavy chain binding 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0034713 type I transforming growth factor beta receptor binding 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0048185 activin binding 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0070697 activin receptor binding 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0140031 phosphorylation-dependent protein binding 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0140537 transcription regulator activator activity 1/548 11/18639 0.0909090909090909 3.0920703384207 0.27988677871757 0.626655592868948 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 7/548 181/18639 0.0386740331491713 1.31541113844417 0.284054219152983 0.631443580843189 GO:0005484 SNAP receptor activity 2/548 36/18639 0.0555555555555556 1.88959854014599 0.286030086270971 0.631443580843189 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/548 36/18639 0.0555555555555556 1.88959854014599 0.286030086270971 0.631443580843189 GO:0016755 aminoacyltransferase activity 17/548 496/18639 0.0342741935483871 1.16576038968684 0.292610061473371 0.631443580843189 GO:0043394 proteoglycan binding 2/548 37/18639 0.0540540540540541 1.83852830933123 0.296991318480198 0.631443580843189 GO:0061135 endopeptidase regulator activity 7/548 184/18639 0.0380434782608696 1.29396421770866 0.297962079774816 0.631443580843189 GO:0003720 telomerase activity 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0004300 enoyl-CoA hydratase activity 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0004859 phospholipase inhibitor activity 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0005049 nuclear export signal receptor activity 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0005078 MAP-kinase scaffold activity 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0008603 cAMP-dependent protein kinase regulator activity 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0010853 cyclase activator activity 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0016273 arginine N-methyltransferase activity 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0016274 protein-arginine N-methyltransferase activity 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0017166 vinculin binding 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0034452 dynactin binding 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0035497 cAMP response element binding 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0036009 protein-glutamine N-methyltransferase activity 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0045295 gamma-catenin binding 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:1990459 transferrin receptor binding 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:1990817 poly(A) RNA polymerase activity 1/548 12/18639 0.0833333333333333 2.83439781021898 0.301071127292982 0.631443580843189 GO:0033218 amide binding 9/548 247/18639 0.0364372469635627 1.23933183604716 0.303441778141376 0.634870904752103 GO:0043531 ADP binding 2/548 38/18639 0.0526315789473684 1.79014598540146 0.307926361791674 0.642693762383591 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3/548 67/18639 0.0447761194029851 1.52296001743109 0.314990184303176 0.649292671739798 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/548 39/18639 0.0512820512820513 1.7442448062886 0.318827292525666 0.649292671739798 GO:0003964 RNA-directed DNA polymerase activity 1/548 13/18639 0.0769230769230769 2.6163672094329 0.321633376836303 0.649292671739798 GO:0005035 death receptor activity 1/548 13/18639 0.0769230769230769 2.6163672094329 0.321633376836303 0.649292671739798 GO:0008035 high-density lipoprotein particle binding 1/548 13/18639 0.0769230769230769 2.6163672094329 0.321633376836303 0.649292671739798 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/548 13/18639 0.0769230769230769 2.6163672094329 0.321633376836303 0.649292671739798 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/548 13/18639 0.0769230769230769 2.6163672094329 0.321633376836303 0.649292671739798 GO:0031994 insulin-like growth factor I binding 1/548 13/18639 0.0769230769230769 2.6163672094329 0.321633376836303 0.649292671739798 GO:0032396 inhibitory MHC class I receptor activity 1/548 13/18639 0.0769230769230769 2.6163672094329 0.321633376836303 0.649292671739798 GO:0039706 co-receptor binding 1/548 13/18639 0.0769230769230769 2.6163672094329 0.321633376836303 0.649292671739798 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/548 13/18639 0.0769230769230769 2.6163672094329 0.321633376836303 0.649292671739798 GO:0071837 HMG box domain binding 1/548 13/18639 0.0769230769230769 2.6163672094329 0.321633376836303 0.649292671739798 GO:0140666 annealing activity 1/548 13/18639 0.0769230769230769 2.6163672094329 0.321633376836303 0.649292671739798 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/548 13/18639 0.0769230769230769 2.6163672094329 0.321633376836303 0.649292671739798 GO:0004725 protein tyrosine phosphatase activity 4/548 98/18639 0.0408163265306122 1.3882764784746 0.325683607867878 0.655932873789979 GO:0030331 nuclear estrogen receptor binding 2/548 40/18639 0.05 1.70063868613139 0.329686673871716 0.658729530455617 GO:0032451 demethylase activity 2/548 40/18639 0.05 1.70063868613139 0.329686673871716 0.658729530455617 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/548 40/18639 0.05 1.70063868613139 0.329686673871716 0.658729530455617 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 5/548 130/18639 0.0384615384615385 1.30818360471645 0.335773143820857 0.658729530455617 GO:0043130 ubiquitin binding 4/548 100/18639 0.04 1.36051094890511 0.339070547269584 0.658729530455617 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/548 41/18639 0.0487804878048781 1.65915969378672 0.340497534198657 0.658729530455617 GO:0017080 sodium channel regulator activity 2/548 41/18639 0.0487804878048781 1.65915969378672 0.340497534198657 0.658729530455617 GO:0005161 platelet-derived growth factor receptor binding 1/548 14/18639 0.0714285714285714 2.42948383733055 0.341591763472924 0.658729530455617 GO:0008191 metalloendopeptidase inhibitor activity 1/548 14/18639 0.0714285714285714 2.42948383733055 0.341591763472924 0.658729530455617 GO:0008331 high voltage-gated calcium channel activity 1/548 14/18639 0.0714285714285714 2.42948383733055 0.341591763472924 0.658729530455617 GO:0008559 ABC-type xenobiotic transporter activity 1/548 14/18639 0.0714285714285714 2.42948383733055 0.341591763472924 0.658729530455617 GO:0015926 glucosidase activity 1/548 14/18639 0.0714285714285714 2.42948383733055 0.341591763472924 0.658729530455617 GO:0016530 metallochaperone activity 1/548 14/18639 0.0714285714285714 2.42948383733055 0.341591763472924 0.658729530455617 GO:0031404 chloride ion binding 1/548 14/18639 0.0714285714285714 2.42948383733055 0.341591763472924 0.658729530455617 GO:0034236 protein kinase A catalytic subunit binding 1/548 14/18639 0.0714285714285714 2.42948383733055 0.341591763472924 0.658729530455617 GO:0042043 neurexin family protein binding 1/548 14/18639 0.0714285714285714 2.42948383733055 0.341591763472924 0.658729530455617 GO:0043176 amine binding 1/548 14/18639 0.0714285714285714 2.42948383733055 0.341591763472924 0.658729530455617 GO:0071933 Arp2/3 complex binding 1/548 14/18639 0.0714285714285714 2.42948383733055 0.341591763472924 0.658729530455617 GO:1901612 cardiolipin binding 1/548 14/18639 0.0714285714285714 2.42948383733055 0.341591763472924 0.658729530455617 GO:0004842 ubiquitin-protein transferase activity 15/548 449/18639 0.0334075723830735 1.13628420008779 0.343205816673441 0.660364763331486 GO:0031492 nucleosomal DNA binding 2/548 42/18639 0.0476190476190476 1.6196558915537 0.351253346215405 0.672412030155407 GO:0004129 cytochrome-c oxidase activity 1/548 15/18639 0.0666666666666667 2.26751824817518 0.360963989707386 0.672412030155407 GO:0004953 icosanoid receptor activity 1/548 15/18639 0.0666666666666667 2.26751824817518 0.360963989707386 0.672412030155407 GO:0005523 tropomyosin binding 1/548 15/18639 0.0666666666666667 2.26751824817518 0.360963989707386 0.672412030155407 GO:0015929 hexosaminidase activity 1/548 15/18639 0.0666666666666667 2.26751824817518 0.360963989707386 0.672412030155407 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/548 15/18639 0.0666666666666667 2.26751824817518 0.360963989707386 0.672412030155407 GO:0016846 carbon-sulfur lyase activity 1/548 15/18639 0.0666666666666667 2.26751824817518 0.360963989707386 0.672412030155407 GO:0033130 acetylcholine receptor binding 1/548 15/18639 0.0666666666666667 2.26751824817518 0.360963989707386 0.672412030155407 GO:0042809 nuclear vitamin D receptor binding 1/548 15/18639 0.0666666666666667 2.26751824817518 0.360963989707386 0.672412030155407 GO:0045504 dynein heavy chain binding 1/548 15/18639 0.0666666666666667 2.26751824817518 0.360963989707386 0.672412030155407 GO:0047372 monoacylglycerol lipase activity 1/548 15/18639 0.0666666666666667 2.26751824817518 0.360963989707386 0.672412030155407 GO:0050700 CARD domain binding 1/548 15/18639 0.0666666666666667 2.26751824817518 0.360963989707386 0.672412030155407 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/548 15/18639 0.0666666666666667 2.26751824817518 0.360963989707386 0.672412030155407 GO:0120283 protein serine/threonine kinase binding 1/548 15/18639 0.0666666666666667 2.26751824817518 0.360963989707386 0.672412030155407 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/548 43/18639 0.0465116279069767 1.58198947547106 0.361948006951402 0.672412030155407 GO:0008375 acetylglucosaminyltransferase activity 2/548 43/18639 0.0465116279069767 1.58198947547106 0.361948006951402 0.672412030155407 GO:0140789 histone phosphatase activity 5/548 136/18639 0.0367647058823529 1.25046962215543 0.370827350124729 0.685825478709336 GO:0001046 core promoter sequence-specific DNA binding 2/548 44/18639 0.0454545454545455 1.54603516921035 0.372575818526658 0.685825478709336 GO:0019205 nucleobase-containing compound kinase activity 2/548 44/18639 0.0454545454545455 1.54603516921035 0.372575818526658 0.685825478709336 GO:0043014 alpha-tubulin binding 2/548 44/18639 0.0454545454545455 1.54603516921035 0.372575818526658 0.685825478709336 GO:0016247 channel regulator activity 6/548 168/18639 0.0357142857142857 1.21474191866528 0.373146345144639 0.685825478709336 GO:0000149 SNARE binding 4/548 106/18639 0.0377358490566038 1.2835008951935 0.379275671033571 0.687729749766442 GO:0004708 MAP kinase kinase activity 1/548 16/18639 0.0625 2.12579835766423 0.379767240010239 0.687729749766442 GO:0008142 oxysterol binding 1/548 16/18639 0.0625 2.12579835766423 0.379767240010239 0.687729749766442 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/548 16/18639 0.0625 2.12579835766423 0.379767240010239 0.687729749766442 GO:0017070 U6 snRNA binding 1/548 16/18639 0.0625 2.12579835766423 0.379767240010239 0.687729749766442 GO:0043023 ribosomal large subunit binding 1/548 16/18639 0.0625 2.12579835766423 0.379767240010239 0.687729749766442 GO:0055102 lipase inhibitor activity 1/548 16/18639 0.0625 2.12579835766423 0.379767240010239 0.687729749766442 GO:0005125 cytokine activity 8/548 234/18639 0.0341880341880342 1.16282987085907 0.382952099523511 0.690437028262816 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/548 45/18639 0.0444444444444444 1.51167883211679 0.383131469682392 0.690437028262816 GO:0141108 transporter regulator activity 6/548 170/18639 0.0352941176470588 1.20045083726921 0.383665123593838 0.690437028262816 GO:0030276 clathrin binding 2/548 46/18639 0.0434782608695652 1.4788162488099 0.393610018044328 0.697340822986343 GO:0030291 protein serine/threonine kinase inhibitor activity 2/548 46/18639 0.0434782608695652 1.4788162488099 0.393610018044328 0.697340822986343 GO:0004659 prenyltransferase activity 1/548 17/18639 0.0588235294117647 2.00075139544869 0.398018195950442 0.697340822986343 GO:0008484 sulfuric ester hydrolase activity 1/548 17/18639 0.0588235294117647 2.00075139544869 0.398018195950442 0.697340822986343 GO:0016018 cyclosporin A binding 1/548 17/18639 0.0588235294117647 2.00075139544869 0.398018195950442 0.697340822986343 GO:0030169 low-density lipoprotein particle binding 1/548 17/18639 0.0588235294117647 2.00075139544869 0.398018195950442 0.697340822986343 GO:0030548 acetylcholine receptor regulator activity 1/548 17/18639 0.0588235294117647 2.00075139544869 0.398018195950442 0.697340822986343 GO:0031489 myosin V binding 1/548 17/18639 0.0588235294117647 2.00075139544869 0.398018195950442 0.697340822986343 GO:0032183 SUMO binding 1/548 17/18639 0.0588235294117647 2.00075139544869 0.398018195950442 0.697340822986343 GO:0036041 long-chain fatty acid binding 1/548 17/18639 0.0588235294117647 2.00075139544869 0.398018195950442 0.697340822986343 GO:0045125 bioactive lipid receptor activity 1/548 17/18639 0.0588235294117647 2.00075139544869 0.398018195950442 0.697340822986343 GO:0046965 nuclear retinoid X receptor binding 1/548 17/18639 0.0588235294117647 2.00075139544869 0.398018195950442 0.697340822986343 GO:1990226 histone methyltransferase binding 1/548 17/18639 0.0588235294117647 2.00075139544869 0.398018195950442 0.697340822986343 GO:0019199 transmembrane receptor protein kinase activity 3/548 78/18639 0.0384615384615385 1.30818360471645 0.403473290635746 0.698561188819021 GO:0043495 protein-membrane adaptor activity 2/548 47/18639 0.0425531914893617 1.44735207330331 0.40400687309162 0.698561188819021 GO:0061733 protein-lysine-acetyltransferase activity 2/548 47/18639 0.0425531914893617 1.44735207330331 0.40400687309162 0.698561188819021 GO:0140359 ABC-type transporter activity 2/548 47/18639 0.0425531914893617 1.44735207330331 0.40400687309162 0.698561188819021 GO:0003823 antigen binding 6/548 174/18639 0.0344827586206897 1.17285426629751 0.40469948004618 0.698561188819021 GO:1902936 phosphatidylinositol bisphosphate binding 4/548 111/18639 0.036036036036036 1.22568553955415 0.412600503468245 0.698561188819021 GO:0140693 molecular condensate scaffold activity 2/548 48/18639 0.0416666666666667 1.41719890510949 0.414317779805376 0.698561188819021 GO:0000400 four-way junction DNA binding 1/548 18/18639 0.0555555555555556 1.88959854014599 0.415733050886494 0.698561188819021 GO:0003746 translation elongation factor activity 1/548 18/18639 0.0555555555555556 1.88959854014599 0.415733050886494 0.698561188819021 GO:0004970 glutamate-gated receptor activity 1/548 18/18639 0.0555555555555556 1.88959854014599 0.415733050886494 0.698561188819021 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/548 18/18639 0.0555555555555556 1.88959854014599 0.415733050886494 0.698561188819021 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/548 18/18639 0.0555555555555556 1.88959854014599 0.415733050886494 0.698561188819021 GO:0017128 phospholipid scramblase activity 1/548 18/18639 0.0555555555555556 1.88959854014599 0.415733050886494 0.698561188819021 GO:0030228 lipoprotein particle receptor activity 1/548 18/18639 0.0555555555555556 1.88959854014599 0.415733050886494 0.698561188819021 GO:0031690 adrenergic receptor binding 1/548 18/18639 0.0555555555555556 1.88959854014599 0.415733050886494 0.698561188819021 GO:0050811 GABA receptor binding 1/548 18/18639 0.0555555555555556 1.88959854014599 0.415733050886494 0.698561188819021 GO:0070064 proline-rich region binding 1/548 18/18639 0.0555555555555556 1.88959854014599 0.415733050886494 0.698561188819021 GO:0098641 cadherin binding involved in cell-cell adhesion 1/548 18/18639 0.0555555555555556 1.88959854014599 0.415733050886494 0.698561188819021 GO:0099602 neurotransmitter receptor regulator activity 1/548 18/18639 0.0555555555555556 1.88959854014599 0.415733050886494 0.698561188819021 GO:1901611 phosphatidylglycerol binding 1/548 18/18639 0.0555555555555556 1.88959854014599 0.415733050886494 0.698561188819021 GO:1990381 ubiquitin-specific protease binding 1/548 18/18639 0.0555555555555556 1.88959854014599 0.415733050886494 0.698561188819021 GO:0008017 microtubule binding 9/548 276/18639 0.0326086956521739 1.10911218660743 0.423762651208407 0.710587277983675 GO:0016763 pentosyltransferase activity 2/548 49/18639 0.0408163265306122 1.3882764784746 0.424538802971685 0.710587277983675 GO:0015101 organic cation transmembrane transporter activity 3/548 81/18639 0.037037037037037 1.25973236009732 0.427128743165365 0.713536776373149 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/548 19/18639 0.0526315789473684 1.79014598540146 0.432927524229182 0.716283159089357 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/548 19/18639 0.0526315789473684 1.79014598540146 0.432927524229182 0.716283159089357 GO:0005520 insulin-like growth factor binding 1/548 19/18639 0.0526315789473684 1.79014598540146 0.432927524229182 0.716283159089357 GO:0008574 plus-end-directed microtubule motor activity 1/548 19/18639 0.0526315789473684 1.79014598540146 0.432927524229182 0.716283159089357 GO:0050145 nucleoside monophosphate kinase activity 1/548 19/18639 0.0526315789473684 1.79014598540146 0.432927524229182 0.716283159089357 GO:0035401 histone H3Y41 kinase activity 4/548 115/18639 0.0347826086956522 1.18305299904792 0.438984733704211 0.722146642085935 GO:0101005 deubiquitinase activity 4/548 115/18639 0.0347826086956522 1.18305299904792 0.438984733704211 0.722146642085935 GO:0140801 histone H2AXY142 kinase activity 4/548 115/18639 0.0347826086956522 1.18305299904792 0.438984733704211 0.722146642085935 GO:0030165 PDZ domain binding 3/548 83/18639 0.036144578313253 1.22937736346847 0.442714889122613 0.723077885258564 GO:0016597 amino acid binding 2/548 51/18639 0.0392156862745098 1.33383426363246 0.444696967037512 0.723077885258564 GO:0030544 Hsp70 protein binding 2/548 51/18639 0.0392156862745098 1.33383426363246 0.444696967037512 0.723077885258564 GO:0000339 RNA cap binding 1/548 20/18639 0.05 1.70063868613139 0.449616875288388 0.723077885258564 GO:0001614 purinergic nucleotide receptor activity 1/548 20/18639 0.05 1.70063868613139 0.449616875288388 0.723077885258564 GO:0016004 phospholipase activator activity 1/548 20/18639 0.05 1.70063868613139 0.449616875288388 0.723077885258564 GO:0016502 nucleotide receptor activity 1/548 20/18639 0.05 1.70063868613139 0.449616875288388 0.723077885258564 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/548 20/18639 0.05 1.70063868613139 0.449616875288388 0.723077885258564 GO:0031418 L-ascorbic acid binding 1/548 20/18639 0.05 1.70063868613139 0.449616875288388 0.723077885258564 GO:0042288 MHC class I protein binding 1/548 20/18639 0.05 1.70063868613139 0.449616875288388 0.723077885258564 GO:0061608 nuclear import signal receptor activity 1/548 20/18639 0.05 1.70063868613139 0.449616875288388 0.723077885258564 GO:0140939 histone H4 methyltransferase activity 1/548 20/18639 0.05 1.70063868613139 0.449616875288388 0.723077885258564 GO:0005080 protein kinase C binding 2/548 52/18639 0.0384615384615385 1.30818360471645 0.454627703945028 0.729502006598028 GO:0004864 protein phosphatase inhibitor activity 2/548 53/18639 0.0377358490566038 1.2835008951935 0.464455722132441 0.729502006598028 GO:0034212 protein N-acetyltransferase activity 2/548 53/18639 0.0377358490566038 1.2835008951935 0.464455722132441 0.729502006598028 GO:0051018 protein kinase A binding 2/548 53/18639 0.0377358490566038 1.2835008951935 0.464455722132441 0.729502006598028 GO:0140296 general transcription initiation factor binding 2/548 53/18639 0.0377358490566038 1.2835008951935 0.464455722132441 0.729502006598028 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/548 21/18639 0.0476190476190476 1.6196558915537 0.465815916716067 0.729502006598028 GO:0009975 cyclase activity 1/548 21/18639 0.0476190476190476 1.6196558915537 0.465815916716067 0.729502006598028 GO:0035613 RNA stem-loop binding 1/548 21/18639 0.0476190476190476 1.6196558915537 0.465815916716067 0.729502006598028 GO:0036122 BMP binding 1/548 21/18639 0.0476190476190476 1.6196558915537 0.465815916716067 0.729502006598028 GO:1904047 S-adenosyl-L-methionine binding 1/548 21/18639 0.0476190476190476 1.6196558915537 0.465815916716067 0.729502006598028 GO:0003925 G protein activity 2/548 54/18639 0.037037037037037 1.25973236009732 0.474178471212963 0.729502006598028 GO:0015485 cholesterol binding 2/548 54/18639 0.037037037037037 1.25973236009732 0.474178471212963 0.729502006598028 GO:0004540 RNA nuclease activity 4/548 121/18639 0.0330578512396694 1.12438921397116 0.477871124616185 0.729502006598028 GO:0016651 oxidoreductase activity, acting on NAD(P)H 3/548 88/18639 0.0340909090909091 1.15952637690776 0.480910893902004 0.729502006598028 GO:0008093 cytoskeletal anchor activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0008970 phospholipase A1 activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0032931 histone H3K56 acetyltransferase activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0043992 histone H3K9 acetyltransferase activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0043993 histone H3K18 acetyltransferase activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0043994 histone H3K23 acetyltransferase activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0043999 histone H2AK5 acetyltransferase activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0044012 histone H2AK9 acetyltransferase activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0044014 histone H2BK5 acetyltransferase activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0044015 histone H2BK12 acetyltransferase activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0044016 histone H3K4 acetyltransferase activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0044017 histone H3K27 acetyltransferase activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0044018 histone H3K36 acetyltransferase activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0046972 histone H4K16 acetyltransferase activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0050321 tau-protein kinase activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0070034 telomerase RNA binding 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0140517 protein-RNA adaptor activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0140908 histone H3K122 acetyltransferase activity 1/548 22/18639 0.0454545454545455 1.54603516921035 0.481539027557167 0.729502006598028 GO:0098632 cell-cell adhesion mediator activity 2/548 55/18639 0.0363636363636364 1.23682813536828 0.483793638867776 0.731631783691269 GO:0019212 phosphatase inhibitor activity 2/548 56/18639 0.0357142857142857 1.21474191866528 0.493299139097628 0.739623044944626 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/548 23/18639 0.0434782608695652 1.4788162488099 0.496800165919882 0.739623044944626 GO:0004602 glutathione peroxidase activity 1/548 23/18639 0.0434782608695652 1.4788162488099 0.496800165919882 0.739623044944626 GO:0016493 C-C chemokine receptor activity 1/548 23/18639 0.0434782608695652 1.4788162488099 0.496800165919882 0.739623044944626 GO:0016849 phosphorus-oxygen lyase activity 1/548 23/18639 0.0434782608695652 1.4788162488099 0.496800165919882 0.739623044944626 GO:0044013 histone H2B acetyltransferase activity 1/548 23/18639 0.0434782608695652 1.4788162488099 0.496800165919882 0.739623044944626 GO:0099186 structural constituent of postsynapse 1/548 23/18639 0.0434782608695652 1.4788162488099 0.496800165919882 0.739623044944626 GO:0140103 catalytic activity, acting on a glycoprotein 1/548 23/18639 0.0434782608695652 1.4788162488099 0.496800165919882 0.739623044944626 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/548 23/18639 0.0434782608695652 1.4788162488099 0.496800165919882 0.739623044944626 GO:0099106 ion channel regulator activity 5/548 160/18639 0.03125 1.06289917883212 0.508640230459563 0.750546709838468 GO:0035035 histone acetyltransferase binding 1/548 24/18639 0.0416666666666667 1.41719890510949 0.511612881276345 0.750546709838468 GO:0043998 histone H2A acetyltransferase activity 1/548 24/18639 0.0416666666666667 1.41719890510949 0.511612881276345 0.750546709838468 GO:0050431 transforming growth factor beta binding 1/548 24/18639 0.0416666666666667 1.41719890510949 0.511612881276345 0.750546709838468 GO:0050699 WW domain binding 1/548 24/18639 0.0416666666666667 1.41719890510949 0.511612881276345 0.750546709838468 GO:0060229 lipase activator activity 1/548 24/18639 0.0416666666666667 1.41719890510949 0.511612881276345 0.750546709838468 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/548 24/18639 0.0416666666666667 1.41719890510949 0.511612881276345 0.750546709838468 GO:0070840 dynein complex binding 1/548 24/18639 0.0416666666666667 1.41719890510949 0.511612881276345 0.750546709838468 GO:0008408 3'-5' exonuclease activity 2/548 58/18639 0.0344827586206897 1.17285426629751 0.511973857755242 0.750546709838468 GO:0019783 ubiquitin-like protein peptidase activity 4/548 127/18639 0.031496062992126 1.07126846370481 0.515676719005892 0.754691564996739 GO:0051213 dioxygenase activity 3/548 93/18639 0.032258064516129 1.09718624911702 0.517827598968771 0.756554898832341 GO:0015459 potassium channel regulator activity 2/548 59/18639 0.0338983050847458 1.15297538042806 0.521139936699578 0.758200102609828 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 4/548 128/18639 0.03125 1.06289917883212 0.521855246341014 0.758200102609828 GO:0001848 complement binding 1/548 25/18639 0.04 1.36051094890511 0.525990326404498 0.758200102609828 GO:0015662 P-type ion transporter activity 1/548 25/18639 0.04 1.36051094890511 0.525990326404498 0.758200102609828 GO:0017056 structural constituent of nuclear pore 1/548 25/18639 0.04 1.36051094890511 0.525990326404498 0.758200102609828 GO:0042974 nuclear retinoic acid receptor binding 1/548 25/18639 0.04 1.36051094890511 0.525990326404498 0.758200102609828 GO:0047617 fatty acyl-CoA hydrolase activity 1/548 25/18639 0.04 1.36051094890511 0.525990326404498 0.758200102609828 GO:0140358 P-type transmembrane transporter activity 1/548 25/18639 0.04 1.36051094890511 0.525990326404498 0.758200102609828 GO:0016757 glycosyltransferase activity 8/548 267/18639 0.0299625468164794 1.01910932502255 0.528569648035369 0.760646137907326 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/548 60/18639 0.0333333333333333 1.13375912408759 0.530190048975707 0.760814203974014 GO:0004175 endopeptidase activity 12/548 405/18639 0.0296296296296296 1.00778588807786 0.530451666575849 0.760814203974014 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/548 61/18639 0.0327868852459016 1.11517290893861 0.539123080237104 0.761755845928226 GO:0001637 G protein-coupled chemoattractant receptor activity 1/548 26/18639 0.0384615384615385 1.30818360471645 0.539945268981608 0.761755845928226 GO:0004950 chemokine receptor activity 1/548 26/18639 0.0384615384615385 1.30818360471645 0.539945268981608 0.761755845928226 GO:0008066 glutamate receptor activity 1/548 26/18639 0.0384615384615385 1.30818360471645 0.539945268981608 0.761755845928226 GO:0016289 acyl-CoA hydrolase activity 1/548 26/18639 0.0384615384615385 1.30818360471645 0.539945268981608 0.761755845928226 GO:0043548 phosphatidylinositol 3-kinase binding 1/548 26/18639 0.0384615384615385 1.30818360471645 0.539945268981608 0.761755845928226 GO:0050681 nuclear androgen receptor binding 1/548 26/18639 0.0384615384615385 1.30818360471645 0.539945268981608 0.761755845928226 GO:0070006 metalloaminopeptidase activity 1/548 26/18639 0.0384615384615385 1.30818360471645 0.539945268981608 0.761755845928226 GO:0070412 R-SMAD binding 1/548 26/18639 0.0384615384615385 1.30818360471645 0.539945268981608 0.761755845928226 GO:0097602 cullin family protein binding 1/548 26/18639 0.0384615384615385 1.30818360471645 0.539945268981608 0.761755845928226 GO:0016874 ligase activity 5/548 167/18639 0.029940119760479 1.01834651864155 0.546706611513384 0.770034475693688 GO:0015179 L-amino acid transmembrane transporter activity 2/548 62/18639 0.032258064516129 1.09718624911702 0.547938081494898 0.770509993880264 GO:0004364 glutathione transferase activity 1/548 27/18639 0.037037037037037 1.25973236009732 0.553490102839561 0.772020175805342 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/548 27/18639 0.037037037037037 1.25973236009732 0.553490102839561 0.772020175805342 GO:0008266 poly(U) RNA binding 1/548 27/18639 0.037037037037037 1.25973236009732 0.553490102839561 0.772020175805342 GO:0008395 steroid hydroxylase activity 1/548 27/18639 0.037037037037037 1.25973236009732 0.553490102839561 0.772020175805342 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/548 27/18639 0.037037037037037 1.25973236009732 0.553490102839561 0.772020175805342 GO:0005507 copper ion binding 2/548 63/18639 0.0317460317460317 1.07977059436913 0.556634260390637 0.774860149369506 GO:0030414 peptidase inhibitor activity 5/548 169/18639 0.029585798816568 1.00629508055112 0.557324005346976 0.774860149369506 GO:0019789 SUMO transferase activity 1/548 28/18639 0.0357142857142857 1.21474191866528 0.566636858891781 0.784014401869527 GO:0036408 histone H3K14 acetyltransferase activity 1/548 28/18639 0.0357142857142857 1.21474191866528 0.566636858891781 0.784014401869527 GO:0051537 2 iron, 2 sulfur cluster binding 1/548 28/18639 0.0357142857142857 1.21474191866528 0.566636858891781 0.784014401869527 GO:0002020 protease binding 4/548 136/18639 0.0294117647058824 1.00037569772435 0.569855918281404 0.785945282493713 GO:0019838 growth factor binding 4/548 136/18639 0.0294117647058824 1.00037569772435 0.569855918281404 0.785945282493713 GO:0001217 DNA-binding transcription repressor activity 8/548 278/18639 0.0287769784172662 0.978784855327417 0.574553874849169 0.791158850031923 GO:0004629 phospholipase C activity 1/548 29/18639 0.0344827586206897 1.17285426629751 0.579397215741349 0.792272158516294 GO:0010484 histone H3 acetyltransferase activity 1/548 29/18639 0.0344827586206897 1.17285426629751 0.579397215741349 0.792272158516294 GO:0043236 laminin binding 1/548 29/18639 0.0344827586206897 1.17285426629751 0.579397215741349 0.792272158516294 GO:0015171 amino acid transmembrane transporter activity 3/548 102/18639 0.0294117647058824 1.00037569772435 0.580505848709147 0.792272158516294 GO:0030295 protein kinase activator activity 4/548 139/18639 0.0287769784172662 0.978784855327417 0.587151100235366 0.792272158516294 GO:0070851 growth factor receptor binding 4/548 139/18639 0.0287769784172662 0.978784855327417 0.587151100235366 0.792272158516294 GO:0008187 poly-pyrimidine tract binding 1/548 30/18639 0.0333333333333333 1.13375912408759 0.591782509979594 0.792272158516294 GO:0016769 transferase activity, transferring nitrogenous groups 1/548 30/18639 0.0333333333333333 1.13375912408759 0.591782509979594 0.792272158516294 GO:0031210 phosphatidylcholine binding 1/548 30/18639 0.0333333333333333 1.13375912408759 0.591782509979594 0.792272158516294 GO:0031624 ubiquitin conjugating enzyme binding 1/548 30/18639 0.0333333333333333 1.13375912408759 0.591782509979594 0.792272158516294 GO:0032452 histone demethylase activity 1/548 30/18639 0.0333333333333333 1.13375912408759 0.591782509979594 0.792272158516294 GO:0033612 receptor serine/threonine kinase binding 1/548 30/18639 0.0333333333333333 1.13375912408759 0.591782509979594 0.792272158516294 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/548 30/18639 0.0333333333333333 1.13375912408759 0.591782509979594 0.792272158516294 GO:0043995 histone H4K5 acetyltransferase activity 1/548 30/18639 0.0333333333333333 1.13375912408759 0.591782509979594 0.792272158516294 GO:0043996 histone H4K8 acetyltransferase activity 1/548 30/18639 0.0333333333333333 1.13375912408759 0.591782509979594 0.792272158516294 GO:0043997 histone H4K12 acetyltransferase activity 1/548 30/18639 0.0333333333333333 1.13375912408759 0.591782509979594 0.792272158516294 GO:0098918 structural constituent of synapse 1/548 30/18639 0.0333333333333333 1.13375912408759 0.591782509979594 0.792272158516294 GO:0042393 histone binding 7/548 247/18639 0.0283400809716599 0.963924761370017 0.592441363641723 0.792272158516294 GO:0004713 protein tyrosine kinase activity 4/548 140/18639 0.0285714285714286 0.971793534932221 0.592825455038295 0.792272158516294 GO:0003777 microtubule motor activity 2/548 68/18639 0.0294117647058824 1.00037569772435 0.598315027147109 0.794680359631445 GO:0032934 sterol binding 2/548 68/18639 0.0294117647058824 1.00037569772435 0.598315027147109 0.794680359631445 GO:0140223 general transcription initiation factor activity 2/548 68/18639 0.0294117647058824 1.00037569772435 0.598315027147109 0.794680359631445 GO:1990841 promoter-specific chromatin binding 2/548 68/18639 0.0294117647058824 1.00037569772435 0.598315027147109 0.794680359631445 GO:0005164 tumor necrosis factor receptor binding 1/548 31/18639 0.032258064516129 1.09718624911702 0.603803746184182 0.794739266617335 GO:0016411 acylglycerol O-acyltransferase activity 1/548 31/18639 0.032258064516129 1.09718624911702 0.603803746184182 0.794739266617335 GO:0047499 calcium-independent phospholipase A2 activity 1/548 31/18639 0.032258064516129 1.09718624911702 0.603803746184182 0.794739266617335 GO:0072349 modified amino acid transmembrane transporter activity 1/548 31/18639 0.032258064516129 1.09718624911702 0.603803746184182 0.794739266617335 GO:0140457 protein demethylase activity 1/548 31/18639 0.032258064516129 1.09718624911702 0.603803746184182 0.794739266617335 GO:0020037 heme binding 4/548 142/18639 0.028169014084507 0.958106302045852 0.604034874577698 0.794739266617335 GO:0002039 p53 binding 2/548 69/18639 0.0289855072463768 0.985877499206601 0.606289394026595 0.794739266617335 GO:0008080 N-acetyltransferase activity 2/548 69/18639 0.0289855072463768 0.985877499206601 0.606289394026595 0.794739266617335 GO:0004497 monooxygenase activity 3/548 106/18639 0.0283018867924528 0.962625671395125 0.606657119993279 0.794739266617335 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/548 32/18639 0.03125 1.06289917883212 0.615471606625448 0.800205919926298 GO:0042910 xenobiotic transmembrane transporter activity 1/548 32/18639 0.03125 1.06289917883212 0.615471606625448 0.800205919926298 GO:0047498 calcium-dependent phospholipase A2 activity 1/548 32/18639 0.03125 1.06289917883212 0.615471606625448 0.800205919926298 GO:0071813 lipoprotein particle binding 1/548 32/18639 0.03125 1.06289917883212 0.615471606625448 0.800205919926298 GO:0071814 protein-lipid complex binding 1/548 32/18639 0.03125 1.06289917883212 0.615471606625448 0.800205919926298 GO:0004843 cysteine-type deubiquitinase activity 3/548 108/18639 0.0277777777777778 0.944799270072993 0.619319988613396 0.803996732205944 GO:0004620 phospholipase activity 3/548 109/18639 0.0275229357798165 0.936131386861314 0.625546784691475 0.810042802270349 GO:0019239 deaminase activity 1/548 33/18639 0.0303030303030303 1.0306901128069 0.62679646068947 0.810042802270349 GO:0030296 protein tyrosine kinase activator activity 1/548 33/18639 0.0303030303030303 1.0306901128069 0.62679646068947 0.810042802270349 GO:0005518 collagen binding 2/548 72/18639 0.0277777777777778 0.944799270072993 0.629489485449583 0.811751659705636 GO:0003713 transcription coactivator activity 7/548 256/18639 0.02734375 0.930036781478102 0.630002158170615 0.811751659705636 GO:0019209 kinase activator activity 4/548 148/18639 0.027027027027027 0.919264154665615 0.636516730544584 0.816899819332149 GO:0043539 protein serine/threonine kinase activator activity 2/548 73/18639 0.0273972602739726 0.931856814318568 0.636982777247177 0.816899819332149 GO:0008376 acetylgalactosaminyltransferase activity 1/548 34/18639 0.0294117647058824 1.00037569772435 0.637788374026144 0.816899819332149 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/548 34/18639 0.0294117647058824 1.00037569772435 0.637788374026144 0.816899819332149 GO:0003678 DNA helicase activity 2/548 74/18639 0.027027027027027 0.919264154665615 0.644356714692614 0.818404151134537 GO:0003684 damaged DNA binding 2/548 74/18639 0.027027027027027 0.919264154665615 0.644356714692614 0.818404151134537 GO:0035064 methylated histone binding 2/548 74/18639 0.027027027027027 0.919264154665615 0.644356714692614 0.818404151134537 GO:0048029 monosaccharide binding 2/548 74/18639 0.027027027027027 0.919264154665615 0.644356714692614 0.818404151134537 GO:0004623 phospholipase A2 activity 1/548 35/18639 0.0285714285714286 0.971793534932221 0.648457117430265 0.818404151134537 GO:0005154 epidermal growth factor receptor binding 1/548 35/18639 0.0285714285714286 0.971793534932221 0.648457117430265 0.818404151134537 GO:0010485 histone H4 acetyltransferase activity 1/548 35/18639 0.0285714285714286 0.971793534932221 0.648457117430265 0.818404151134537 GO:0016229 steroid dehydrogenase activity 1/548 35/18639 0.0285714285714286 0.971793534932221 0.648457117430265 0.818404151134537 GO:0034061 DNA polymerase activity 1/548 35/18639 0.0285714285714286 0.971793534932221 0.648457117430265 0.818404151134537 GO:0140566 histone reader activity 1/548 35/18639 0.0285714285714286 0.971793534932221 0.648457117430265 0.818404151134537 GO:0046906 tetrapyrrole binding 4/548 152/18639 0.0263157894736842 0.89507299270073 0.657187864939382 0.820659097181272 GO:0051536 iron-sulfur cluster binding 2/548 76/18639 0.0263157894736842 0.89507299270073 0.658748708832532 0.820659097181272 GO:0098631 cell adhesion mediator activity 2/548 76/18639 0.0263157894736842 0.89507299270073 0.658748708832532 0.820659097181272 GO:0140034 methylation-dependent protein binding 2/548 76/18639 0.0263157894736842 0.89507299270073 0.658748708832532 0.820659097181272 GO:0000993 RNA polymerase II complex binding 1/548 36/18639 0.0277777777777778 0.944799270072993 0.658812175463388 0.820659097181272 GO:0004190 aspartic-type endopeptidase activity 1/548 36/18639 0.0277777777777778 0.944799270072993 0.658812175463388 0.820659097181272 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/548 36/18639 0.0277777777777778 0.944799270072993 0.658812175463388 0.820659097181272 GO:0045505 dynein intermediate chain binding 1/548 36/18639 0.0277777777777778 0.944799270072993 0.658812175463388 0.820659097181272 GO:0055106 ubiquitin-protein transferase regulator activity 1/548 36/18639 0.0277777777777778 0.944799270072993 0.658812175463388 0.820659097181272 GO:0051540 metal cluster binding 2/548 77/18639 0.025974025974026 0.883448668120201 0.665768032194172 0.828127047260283 GO:0070001 aspartic-type peptidase activity 1/548 37/18639 0.027027027027027 0.919264154665615 0.668862754824032 0.830777658009101 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 7/548 268/18639 0.0261194029850746 0.888393343501471 0.676913144564104 0.838063806751009 GO:0008236 serine-type peptidase activity 5/548 194/18639 0.0257731958762887 0.876617879449168 0.678378654030909 0.838063806751009 GO:0005109 frizzled binding 1/548 38/18639 0.0263157894736842 0.89507299270073 0.678617792473555 0.838063806751009 GO:0042162 telomeric DNA binding 1/548 38/18639 0.0263157894736842 0.89507299270073 0.678617792473555 0.838063806751009 GO:0048306 calcium-dependent protein binding 2/548 80/18639 0.025 0.850319343065693 0.68612823044234 0.846119972265893 GO:0000217 DNA secondary structure binding 1/548 39/18639 0.0256410256410256 0.872122403144301 0.688085963524816 0.846119972265893 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/548 39/18639 0.0256410256410256 0.872122403144301 0.688085963524816 0.846119972265893 GO:0001216 DNA-binding transcription activator activity 13/548 491/18639 0.0264765784114053 0.900541870456539 0.689384832136117 0.846509580201329 GO:0016758 hexosyltransferase activity 5/548 197/18639 0.0253807106598985 0.863268368594613 0.691314171112889 0.846551611031355 GO:0003697 single-stranded DNA binding 3/548 121/18639 0.0247933884297521 0.843291910478374 0.694752776629411 0.846551611031355 GO:0016791 phosphatase activity 7/548 273/18639 0.0256410256410256 0.872122403144301 0.69532025416433 0.846551611031355 GO:0017171 serine hydrolase activity 5/548 198/18639 0.0252525252525253 0.858908427339084 0.695546427198215 0.846551611031355 GO:0022804 active transmembrane transporter activity 12/548 457/18639 0.0262582056892779 0.893114408471625 0.695846493643971 0.846551611031355 GO:0050997 quaternary ammonium group binding 1/548 40/18639 0.025 0.850319343065693 0.697275688900536 0.846551611031355 GO:0071855 neuropeptide receptor binding 1/548 40/18639 0.025 0.850319343065693 0.697275688900536 0.846551611031355 GO:0071949 FAD binding 1/548 40/18639 0.025 0.850319343065693 0.697275688900536 0.846551611031355 GO:0004866 endopeptidase inhibitor activity 4/548 161/18639 0.0248447204968944 0.845037856462801 0.700742392403016 0.849563913152461 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/548 41/18639 0.024390243902439 0.82957984689336 0.706195142768083 0.854972209362483 GO:0004402 histone acetyltransferase activity 1/548 42/18639 0.0238095238095238 0.809827945776851 0.714852259757173 0.859417918982821 GO:0004520 DNA endonuclease activity 1/548 42/18639 0.0238095238095238 0.809827945776851 0.714852259757173 0.859417918982821 GO:0035198 miRNA binding 1/548 42/18639 0.0238095238095238 0.809827945776851 0.714852259757173 0.859417918982821 GO:0042056 chemoattractant activity 1/548 42/18639 0.0238095238095238 0.809827945776851 0.714852259757173 0.859417918982821 GO:0043175 RNA polymerase core enzyme binding 1/548 42/18639 0.0238095238095238 0.809827945776851 0.714852259757173 0.859417918982821 GO:0005245 voltage-gated calcium channel activity 1/548 43/18639 0.0232558139534884 0.790994737735529 0.723254741966834 0.867742366978786 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/548 86/18639 0.0232558139534884 0.790994737735529 0.723789746934742 0.867742366978786 GO:0031490 chromatin DNA binding 3/548 128/18639 0.0234375 0.797174384124088 0.730431083121306 0.873742668233058 GO:0016790 thiolester hydrolase activity 1/548 44/18639 0.0227272727272727 0.773017584605176 0.731410065767768 0.873742668233058 GO:0005516 calmodulin binding 5/548 207/18639 0.0241545893719807 0.821564582672168 0.731835506339058 0.873742668233058 GO:0051539 4 iron, 4 sulfur cluster binding 1/548 45/18639 0.0222222222222222 0.755839416058394 0.739325488406072 0.878625673457781 GO:0140303 intramembrane lipid transporter activity 1/548 45/18639 0.0222222222222222 0.755839416058394 0.739325488406072 0.878625673457781 GO:0016298 lipase activity 3/548 130/18639 0.0230769230769231 0.784910162829871 0.740002597366994 0.878625673457781 GO:0016798 hydrolase activity, acting on glycosyl bonds 3/548 130/18639 0.0230769230769231 0.784910162829871 0.740002597366994 0.878625673457781 GO:0004180 carboxypeptidase activity 1/548 46/18639 0.0217391304347826 0.739408124404951 0.747008054414111 0.880002402601189 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/548 46/18639 0.0217391304347826 0.739408124404951 0.747008054414111 0.880002402601189 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/548 91/18639 0.021978021978022 0.747533488409401 0.752193958634615 0.880002402601189 GO:0140030 modification-dependent protein binding 4/548 173/18639 0.023121387283237 0.786422513817982 0.752407069159513 0.880002402601189 GO:0005504 fatty acid binding 1/548 47/18639 0.0212765957446809 0.723676036651654 0.754464601834165 0.880002402601189 GO:0061749 forked DNA-dependent helicase activity 1/548 47/18639 0.0212765957446809 0.723676036651654 0.754464601834165 0.880002402601189 GO:0140938 histone H3 methyltransferase activity 1/548 47/18639 0.0212765957446809 0.723676036651654 0.754464601834165 0.880002402601189 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/548 47/18639 0.0212765957446809 0.723676036651654 0.754464601834165 0.880002402601189 GO:0043178 alcohol binding 2/548 92/18639 0.0217391304347826 0.739408124404951 0.757563690867419 0.880002402601189 GO:0052689 carboxylic ester hydrolase activity 2/548 92/18639 0.0217391304347826 0.739408124404951 0.757563690867419 0.880002402601189 GO:0009378 four-way junction helicase activity 1/548 48/18639 0.0208333333333333 0.708599452554745 0.76170176826031 0.880002402601189 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/548 48/18639 0.0208333333333333 0.708599452554745 0.76170176826031 0.880002402601189 GO:0036121 double-stranded DNA helicase activity 1/548 48/18639 0.0208333333333333 0.708599452554745 0.76170176826031 0.880002402601189 GO:0043138 3'-5' DNA helicase activity 1/548 48/18639 0.0208333333333333 0.708599452554745 0.76170176826031 0.880002402601189 GO:0004252 serine-type endopeptidase activity 4/548 176/18639 0.0227272727272727 0.773017584605176 0.764194846577898 0.880002402601189 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 12/548 484/18639 0.0247933884297521 0.843291910478374 0.766145271107674 0.880002402601189 GO:0016410 N-acyltransferase activity 2/548 94/18639 0.0212765957446809 0.723676036651654 0.768002007120648 0.880002402601189 GO:0005004 GPI-linked ephrin receptor activity 1/548 49/18639 0.0204081632653061 0.694138239237301 0.768725996703823 0.880002402601189 GO:0005008 hepatocyte growth factor receptor activity 1/548 49/18639 0.0204081632653061 0.694138239237301 0.768725996703823 0.880002402601189 GO:0005009 insulin receptor activity 1/548 49/18639 0.0204081632653061 0.694138239237301 0.768725996703823 0.880002402601189 GO:0005011 macrophage colony-stimulating factor receptor activity 1/548 49/18639 0.0204081632653061 0.694138239237301 0.768725996703823 0.880002402601189 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/548 49/18639 0.0204081632653061 0.694138239237301 0.768725996703823 0.880002402601189 GO:0005020 stem cell factor receptor activity 1/548 49/18639 0.0204081632653061 0.694138239237301 0.768725996703823 0.880002402601189 GO:0008288 boss receptor activity 1/548 49/18639 0.0204081632653061 0.694138239237301 0.768725996703823 0.880002402601189 GO:0036332 placental growth factor receptor activity 1/548 49/18639 0.0204081632653061 0.694138239237301 0.768725996703823 0.880002402601189 GO:0038062 protein tyrosine kinase collagen receptor activity 1/548 49/18639 0.0204081632653061 0.694138239237301 0.768725996703823 0.880002402601189 GO:0060175 brain-derived neurotrophic factor receptor activity 1/548 49/18639 0.0204081632653061 0.694138239237301 0.768725996703823 0.880002402601189 GO:0004867 serine-type endopeptidase inhibitor activity 2/548 95/18639 0.0210526315789474 0.716058394160584 0.77307314991723 0.880788580486993 GO:0005006 epidermal growth factor receptor activity 1/548 50/18639 0.02 0.680255474452555 0.775543541287271 0.880788580486993 GO:0005007 fibroblast growth factor receptor activity 1/548 50/18639 0.02 0.680255474452555 0.775543541287271 0.880788580486993 GO:0005017 platelet-derived growth factor receptor activity 1/548 50/18639 0.02 0.680255474452555 0.775543541287271 0.880788580486993 GO:0005019 platelet-derived growth factor beta-receptor activity 1/548 50/18639 0.02 0.680255474452555 0.775543541287271 0.880788580486993 GO:0032813 tumor necrosis factor receptor superfamily binding 1/548 50/18639 0.02 0.680255474452555 0.775543541287271 0.880788580486993 GO:0016407 acetyltransferase activity 2/548 96/18639 0.0208333333333333 0.708599452554745 0.778047340493882 0.882469483560167 GO:0005010 insulin-like growth factor receptor activity 1/548 51/18639 0.0196078431372549 0.66691713181623 0.782160472772266 0.883646562948484 GO:0005021 vascular endothelial growth factor receptor activity 1/548 51/18639 0.0196078431372549 0.66691713181623 0.782160472772266 0.883646562948484 GO:0005030 neurotrophin receptor activity 1/548 51/18639 0.0196078431372549 0.66691713181623 0.782160472772266 0.883646562948484 GO:0003730 mRNA 3'-UTR binding 6/548 262/18639 0.0229007633587786 0.778918482197582 0.786066933432623 0.886897508663509 GO:0005003 ephrin receptor activity 1/548 53/18639 0.0188679245283019 0.64175044759675 0.794815894729459 0.88862684987911 GO:0005005 transmembrane-ephrin receptor activity 1/548 53/18639 0.0188679245283019 0.64175044759675 0.794815894729459 0.88862684987911 GO:0005246 calcium channel regulator activity 1/548 53/18639 0.0188679245283019 0.64175044759675 0.794815894729459 0.88862684987911 GO:0005544 calcium-dependent phospholipid binding 1/548 53/18639 0.0188679245283019 0.64175044759675 0.794815894729459 0.88862684987911 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/548 53/18639 0.0188679245283019 0.64175044759675 0.794815894729459 0.88862684987911 GO:0038064 collagen receptor activity 1/548 53/18639 0.0188679245283019 0.64175044759675 0.794815894729459 0.88862684987911 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/548 53/18639 0.0188679245283019 0.64175044759675 0.794815894729459 0.88862684987911 GO:0140463 chromatin-protein adaptor activity 1/548 54/18639 0.0185185185185185 0.629866180048662 0.800865657437317 0.894230824755139 GO:0008194 UDP-glycosyltransferase activity 3/548 145/18639 0.0206896551724138 0.703712559778505 0.803394382846308 0.895893865476737 GO:0140098 catalytic activity, acting on RNA 9/548 387/18639 0.0232558139534884 0.790994737735529 0.806684889473523 0.897300136258045 GO:0008374 O-acyltransferase activity 1/548 55/18639 0.0181818181818182 0.618414067684141 0.806737361484901 0.897300136258045 GO:0000287 magnesium ion binding 5/548 230/18639 0.0217391304347826 0.739408124404951 0.810040694372792 0.898901086937221 GO:0004722 protein serine/threonine phosphatase activity 2/548 103/18639 0.0194174757281553 0.660442208206364 0.810262348666149 0.898901086937221 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/548 56/18639 0.0178571428571429 0.607370959332638 0.812436238255579 0.900154289686772 GO:0019842 vitamin binding 3/548 150/18639 0.02 0.680255474452555 0.82142496903671 0.907564386200897 GO:0008013 beta-catenin binding 2/548 106/18639 0.0188679245283019 0.64175044759675 0.822746379497043 0.907564386200897 GO:0017116 single-stranded DNA helicase activity 1/548 58/18639 0.0172413793103448 0.586427133148754 0.823335672864387 0.907564386200897 GO:0061980 regulatory RNA binding 1/548 58/18639 0.0172413793103448 0.586427133148754 0.823335672864387 0.907564386200897 GO:0031593 polyubiquitin modification-dependent protein binding 1/548 59/18639 0.0169491525423729 0.576487690214029 0.828545944177574 0.910977811072791 GO:0036002 pre-mRNA binding 1/548 59/18639 0.0169491525423729 0.576487690214029 0.828545944177574 0.910977811072791 GO:0005496 steroid binding 2/548 108/18639 0.0185185185185185 0.629866180048662 0.830654710450181 0.911885322434979 GO:0001098 basal transcription machinery binding 1/548 60/18639 0.0166666666666667 0.566879562043796 0.833602823757266 0.911885322434979 GO:0001099 basal RNA polymerase II transcription machinery binding 1/548 60/18639 0.0166666666666667 0.566879562043796 0.833602823757266 0.911885322434979 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/548 60/18639 0.0166666666666667 0.566879562043796 0.833602823757266 0.911885322434979 GO:0042578 phosphoric ester hydrolase activity 8/548 363/18639 0.0220385674931129 0.74959280931411 0.840922556951594 0.918726545110614 GO:0022824 transmitter-gated monoatomic ion channel activity 1/548 63/18639 0.0158730158730159 0.539885297184567 0.847897533548661 0.922837972119881 GO:0022835 transmitter-gated channel activity 1/548 63/18639 0.0158730158730159 0.539885297184567 0.847897533548661 0.922837972119881 GO:1901682 sulfur compound transmembrane transporter activity 1/548 63/18639 0.0158730158730159 0.539885297184567 0.847897533548661 0.922837972119881 GO:0004536 DNA nuclease activity 1/548 64/18639 0.015625 0.531449589416058 0.852384621813914 0.926551757885995 GO:0008235 metalloexopeptidase activity 1/548 66/18639 0.0151515151515152 0.515345056403451 0.860966272832856 0.934701419624587 GO:0016500 protein-hormone receptor activity 1/548 67/18639 0.0149253731343284 0.507653339143698 0.865068490163799 0.935619872674021 GO:0042054 histone methyltransferase activity 1/548 67/18639 0.0149253731343284 0.507653339143698 0.865068490163799 0.935619872674021 GO:0050840 extracellular matrix binding 1/548 67/18639 0.0149253731343284 0.507653339143698 0.865068490163799 0.935619872674021 GO:0005548 phospholipid transporter activity 1/548 68/18639 0.0147058823529412 0.500187848862173 0.869049885134197 0.938748121535937 GO:0016279 protein-lysine N-methyltransferase activity 1/548 69/18639 0.0144927536231884 0.492938749603301 0.872914010003427 0.940564845778692 GO:0098960 postsynaptic neurotransmitter receptor activity 1/548 69/18639 0.0144927536231884 0.492938749603301 0.872914010003427 0.940564845778692 GO:0016278 lysine N-methyltransferase activity 1/548 70/18639 0.0142857142857143 0.48589676746611 0.876664312777693 0.94095698215243 GO:0005261 monoatomic cation channel activity 7/548 341/18639 0.0205278592375367 0.698209431256288 0.877477609829979 0.94095698215243 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/548 122/18639 0.0163934426229508 0.557586454469307 0.877644331381153 0.94095698215243 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/548 122/18639 0.0163934426229508 0.557586454469307 0.877644331381153 0.94095698215243 GO:0140299 molecular sensor activity 1/548 71/18639 0.0140845070422535 0.479053151022926 0.880304140264247 0.942636234668051 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/548 73/18639 0.0136986301369863 0.465928407159284 0.887265268311133 0.948911490427043 GO:0004519 endonuclease activity 2/548 127/18639 0.015748031496063 0.535634231852405 0.891285885816822 0.951360830538811 GO:0022832 voltage-gated channel activity 3/548 175/18639 0.0171428571428571 0.583076120959333 0.891762820273039 0.951360830538811 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/548 132/18639 0.0151515151515152 0.515345056403451 0.903504738798652 0.957972029840168 GO:0033293 monocarboxylic acid binding 1/548 79/18639 0.0126582278481013 0.430541439526933 0.905816141062695 0.957972029840168 GO:0000049 tRNA binding 1/548 80/18639 0.0125 0.425159671532847 0.908597000690801 0.957972029840168 GO:0008237 metallopeptidase activity 3/548 184/18639 0.016304347826087 0.554556093303713 0.910260019305245 0.957972029840168 GO:0033192 calmodulin-dependent protein phosphatase activity 1/548 81/18639 0.0123456790123457 0.419910786699108 0.911295898455844 0.957972029840168 GO:0140791 histone H2AXS140 phosphatase activity 1/548 81/18639 0.0123456790123457 0.419910786699108 0.911295898455844 0.957972029840168 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/548 81/18639 0.0123456790123457 0.419910786699108 0.911295898455844 0.957972029840168 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/548 81/18639 0.0123456790123457 0.419910786699108 0.911295898455844 0.957972029840168 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/548 81/18639 0.0123456790123457 0.419910786699108 0.911295898455844 0.957972029840168 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/548 81/18639 0.0123456790123457 0.419910786699108 0.911295898455844 0.957972029840168 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/548 81/18639 0.0123456790123457 0.419910786699108 0.911295898455844 0.957972029840168 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/548 81/18639 0.0123456790123457 0.419910786699108 0.911295898455844 0.957972029840168 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/548 82/18639 0.0121951219512195 0.41478992344668 0.913915245780244 0.958155898831842 GO:0033549 MAP kinase phosphatase activity 1/548 82/18639 0.0121951219512195 0.41478992344668 0.913915245780244 0.958155898831842 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/548 83/18639 0.0120481927710843 0.409792454489491 0.91645738326542 0.958155898831842 GO:0046943 carboxylic acid transmembrane transporter activity 3/548 188/18639 0.0159574468085106 0.54275702748874 0.917521810572318 0.958155898831842 GO:0140767 enzyme-substrate adaptor activity 2/548 139/18639 0.0143884892086331 0.489392427663708 0.918469594501818 0.958155898831842 GO:0017018 myosin phosphatase activity 1/548 84/18639 0.0119047619047619 0.404913972888425 0.918924582768037 0.958155898831842 GO:0005342 organic acid transmembrane transporter activity 3/548 189/18639 0.0158730158730159 0.539885297184567 0.919251656999922 0.958155898831842 GO:0050660 flavin adenine dinucleotide binding 1/548 86/18639 0.0116279069767442 0.395497368867764 0.923642923562302 0.961570289988773 GO:0008081 phosphoric diester hydrolase activity 1/548 87/18639 0.0114942528735632 0.390951422099169 0.925898282689551 0.962755512277917 GO:0042562 hormone binding 1/548 94/18639 0.0106382978723404 0.361838018325827 0.939929508332002 0.976061606986662 GO:0008276 protein methyltransferase activity 1/548 95/18639 0.0105263157894737 0.358029197080292 0.941704575974712 0.976061606986662 GO:0003774 cytoskeletal motor activity 2/548 153/18639 0.0130718954248366 0.44461142121082 0.942091945490606 0.976061606986662 GO:0030594 neurotransmitter receptor activity 1/548 97/18639 0.0103092783505155 0.350647151779667 0.945099173298846 0.978001785574556 GO:0008170 N-methyltransferase activity 1/548 98/18639 0.0102040816326531 0.34706911961865 0.946721741146555 0.978506164110708 GO:0004222 metalloendopeptidase activity 1/548 110/18639 0.00909090909090909 0.30920703384207 0.962833810876792 0.99247291421033 GO:1901681 sulfur compound binding 4/548 275/18639 0.0145454545454545 0.494731254147313 0.963002736498422 0.99247291421033 GO:0008201 heparin binding 2/548 172/18639 0.0116279069767442 0.395497368867764 0.963942846494698 0.99247291421033 GO:0005244 voltage-gated monoatomic ion channel activity 2/548 173/18639 0.0115606936416185 0.393211256908991 0.964840257666191 0.99247291421033 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/548 229/18639 0.0131004366812227 0.44558218850604 0.96641843258357 0.992911428947601 GO:0001221 transcription coregulator binding 1/548 115/18639 0.00869565217391304 0.29576324976198 0.968014717810312 0.993367484229154 GO:0005539 glycosaminoglycan binding 3/548 242/18639 0.012396694214876 0.421645955239187 0.975022735613063 0.999369319974388 GO:0005216 monoatomic ion channel activity 7/548 448/18639 0.015625 0.531449589416058 0.979173932093792 0.999981338361847 GO:0005262 calcium channel activity 1/548 131/18639 0.00763358778625954 0.259639494065861 0.980221335448807 0.999981338361847 GO:0005179 hormone activity 1/548 132/18639 0.00757575757575758 0.257672528201725 0.980806958323999 0.999981338361847 GO:0015297 antiporter activity 1/548 135/18639 0.00740740740740741 0.251946472019465 0.98246200126422 0.999981338361847 GO:0022843 voltage-gated monoatomic cation channel activity 1/548 143/18639 0.00699300699300699 0.2378515644939 0.986211666204129 0.999981338361847 GO:0008514 organic anion transmembrane transporter activity 3/548 269/18639 0.0111524163568773 0.379324614007001 0.986683800319267 0.999981338361847 GO:0015085 calcium ion transmembrane transporter activity 1/548 147/18639 0.00680272108843537 0.2313794130791 0.987774673603272 0.999981338361847 GO:0015079 potassium ion transmembrane transporter activity 1/548 160/18639 0.00625 0.212579835766423 0.991732687035002 0.999981338361847 GO:0015081 sodium ion transmembrane transporter activity 1/548 164/18639 0.00609756097560976 0.20739496172334 0.992670670461646 0.999981338361847 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/548 167/18639 0.00598802395209581 0.20366930372831 0.993303750807233 0.999981338361847 GO:0005201 extracellular matrix structural constituent 1/548 168/18639 0.00595238095238095 0.202456986444213 0.993502405233264 0.999981338361847 GO:0005319 lipid transporter activity 1/548 178/18639 0.00561797752808989 0.191082998441729 0.995192456464684 0.999981338361847 GO:0022836 gated channel activity 3/548 318/18639 0.00943396226415094 0.320875223798375 0.995918553640851 0.999981338361847 GO:0015276 ligand-gated monoatomic ion channel activity 1/548 186/18639 0.00537634408602151 0.182864374852837 0.996222470210177 0.999981338361847 GO:0022834 ligand-gated channel activity 1/548 188/18639 0.00531914893617021 0.180919009162914 0.996443507765632 0.999981338361847 GO:0008168 methyltransferase activity 1/548 204/18639 0.00490196078431373 0.166729282954058 0.997805023860985 0.999981338361847 GO:0016741 transferase activity, transferring one-carbon groups 1/548 215/18639 0.00465116279069767 0.158198947547106 0.998425190203704 0.999981338361847 GO:0045182 translation regulator activity 2/548 356/18639 0.00561797752808989 0.191082998441729 0.999736846534328 0.999981338361847 GO:0015291 secondary active transmembrane transporter activity 1/548 287/18639 0.00348432055749129 0.118511406699051 0.99982168062372 0.999981338361847 GO:0030371 translation repressor activity 1/548 329/18639 0.00303951367781155 0.103382290950236 0.999950156767119 0.999981338361847 GO:0046873 metal ion transmembrane transporter activity 2/548 450/18639 0.00444444444444444 0.151167883211679 0.999981338361847 0.999981338361847