category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Metabolism	Energy metabolism	hsa00910	Nitrogen metabolism	3/100	17/9376	16.5458823529412	CA2/CA1/CA8	6.66086117188257
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	6/100	105/9376	5.35771428571429	BCL2L1/OPTN/PINK1/NRAS/FOXO3/OPA1	4.66224808741229
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	5/100	71/9376	6.60281690140845	HK1/SLC2A1/NRAS/SLC1A5/SLC7A5	4.92019917587721
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	4/100	42/9376	8.92952380952381	NCOA4/PCBP2/GCLM/GCLC	5.34740555190607
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	4/100	50/9376	7.5008	HBA1/HBA2/GYPB/GYPA	4.78530220431321
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	3/100	32/9376	8.79	BCL2L1/BIRC2/BBC3	4.58301522680067
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	6/100	169/9376	3.3287573964497	BCL2L1/OPTN/WIPI2/NRAS/VPS11/ATG4A	3.17185843789375
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	5/100	142/9376	3.30140845070423	UBE2O/BIRC2/UBE2H/DDB1/CDC27	2.86911666990762
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	5/100	144/9376	3.25555555555556	ADIPOR1/MAP2K3/LPIN2/FOXO3/C5	2.83199279970508
Metabolism	Lipid metabolism	hsa00100	Steroid biosynthesis	2/100	20/9376	9.376	LSS/MSMO1	3.89324583938533
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	4/100	104/9376	3.60615384615385	PHOSPHO1/AGPAT3/LPIN2/CEPT1	2.77482293681314
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	5/100	157/9376	2.9859872611465	MAP2K3/E2F2/NRAS/FOXO3/HIPK1	2.60549140814012
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	5/100	158/9376	2.96708860759494	LPIN2/NRAS/SLC7A5/NPRL3/STRADB	2.58904371251692
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	6/100	224/9376	2.51142857142857	BCL2L1/TCF3/SLC2A1/E2F2/NRAS/CDC27	2.37716265735259
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	2/100	28/9376	6.69714285714286	CA2/SLC4A1	3.13459936770222
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	3/100	73/9376	3.85315068493151	E2F2/NRAS/FOXO3	2.54085508765958
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	5/100	180/9376	2.60444444444444	BCL2L1/BIRC2/SRSF8/C5/ZC3HAV1	2.25666307767046
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	2/100	32/9376	5.86	WIPI2/ATG4A	2.85923671402455
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	3/100	75/9376	3.7504	BCL2L1/BIRC2/BBC3	2.48294407103747
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	3/100	77/9376	3.65298701298701	BCL2L1/E2F2/NRAS	2.4269880108794
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	6/100	253/9376	2.22355731225296	HK1/BCL2L1/FOXO4/UBE2V1/WIPI2/FOXO3	2.04842943671328
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	3/100	80/9376	3.516	BCL2L1/NRAS/FOXO3	2.34645830213298
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	2/100	36/9376	5.20888888888889	HK1/PGM2L1	2.62694234618023
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	4/100	137/9376	2.73751824817518	BCL2L1/BIRC2/NRAS/BBC3	2.12707323394464
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	2/100	37/9376	5.06810810810811	HBA1/HBA2	2.57423640675814
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	2/100	37/9376	5.06810810810811	NCOA4/NRAS	2.57423640675814
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	2/100	41/9376	4.57365853658537	E2F2/NRAS	2.38096542406302
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	3/100	90/9376	3.12533333333333	ADIPOR1/NRAS/FOXO3	2.10348411626265
Organismal Systems	Digestive system	hsa04976	Bile secretion	3/100	90/9376	3.12533333333333	CA2/ABCC4/SLC2A1	2.10348411626265
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	3/100	93/9376	3.02451612903226	BCL2L1/BIRC2/E2F2	2.03715375293477
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	4/100	154/9376	2.43532467532468	GCLM/ALAS2/CPOX/GCLC	1.86467531154057
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	2/100	45/9376	4.16711111111111	ABCC4/ABCB7	2.21111194263692
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	4/100	156/9376	2.40410256410256	RSAD2/E2F2/NRAS/IFIT1B	1.83611948464912
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/100	46/9376	4.07652173913043	ALAS2/CPOX	2.17171759719755
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	4/100	163/9376	2.30085889570552	MAP2K3/E2F2/DDB1/NRAS	1.73951719465551
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	3/100	110/9376	2.55709090909091	HK1/SLC2A1/MKNK2	1.70556954274709
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	2/100	54/9376	3.47259259259259	GCLM/GCLC	1.89190864925779
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	3/100	112/9376	2.51142857142857	BCL2L1/BIRC2/MAP2K3	1.67071600882441
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	2/100	59/9376	3.17830508474576	GCLM/GCLC	1.74265706582202
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	2/100	59/9376	3.17830508474576	NRAS/FOXO3	1.74265706582202
Metabolism	Glycan biosynthesis and metabolism	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/100	14/9376	6.69714285714286	ST3GAL1	2.21483856703558
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	3/100	122/9376	2.3055737704918	ADIPOR1/FOXO3/STRADB	1.50702984226681
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	2/100	62/9376	3.02451612903226	NRAS/FOXO3	1.66055871884555
Metabolism	Glycan biosynthesis and metabolism	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/100	15/9376	6.25066666666667	ST3GAL1	2.11302299616967
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	2/100	65/9376	2.88492307692308	AGPAT3/LPIN2	1.58327886589305
Metabolism	Glycan biosynthesis and metabolism	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	1/100	16/9376	5.86	ST3GAL1	2.02005690846179
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	2/100	67/9376	2.79880597014925	HK1/MINPP1	1.53417702505289
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	2/100	68/9376	2.75764705882353	PIM1/NRAS	1.51029995351424
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	4/100	201/9376	1.86587064676617	BCL2L1/BIRC2/TCF3/LYL1	1.28840759915028
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	2/100	69/9376	2.71768115942029	MAP2K3/NRAS	1.48685120344661
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	3/100	133/9376	2.11488721804511	FOXO4/NRAS/FOXO3	1.34448372228829
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	2/100	70/9376	2.67885714285714	ADIPOR1/SLC2A1	1.46381605750463
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	2/100	70/9376	2.67885714285714	SLC2A1/NRAS	1.46381605750463
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/100	71/9376	2.64112676056338	NRAS/FOXO3	1.44118051275317
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	3/100	138/9376	2.03826086956522	HK1/NRAS/MKNK2	1.27574042928576
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	2/100	73/9376	2.56876712328767	NUP153/FURIN	1.39705552448039
Human Diseases	Cancer: specific types	hsa05218	Melanoma	2/100	73/9376	2.56876712328767	E2F2/NRAS	1.39705552448039
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/100	75/9376	2.50026666666667	BCL2L1/BBC3	1.35437689971464
Human Diseases	Cancer: specific types	hsa05214	Glioma	2/100	76/9376	2.46736842105263	E2F2/NRAS	1.33355139659288
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	4/100	214/9376	1.75252336448598	BCL2L1/MAP2K3/DDB1/NRAS	1.15621074132903
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	2/100	77/9376	2.43532467532468	BCL2L1/E2F2	1.31305421461911
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	6/100	368/9376	1.52869565217391	BCL2L1/OPTN/NUP153/MAP2K3/PINK1/WIPI2	1.07428800769781
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	2/100	78/9376	2.40410256410256	PIP4K2A/MINPP1	1.29287527799394
Organismal Systems	Endocrine system	hsa04614	Renin-angiotensin system	1/100	23/9376	4.07652173913043	CPA3	1.53374693295152
Organismal Systems	Excretory system	hsa04964	Proximal tubule bicarbonate reclamation	1/100	23/9376	4.07652173913043	CA2	1.53374693295152
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	3/100	157/9376	1.7915923566879	SLC16A1/SLC2A1/VPS11	1.03851979539337
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	3/100	157/9376	1.7915923566879	BIRC2/MOB1B/BBC3	1.03851979539337
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	4/100	232/9376	1.61655172413793	PIP4K2A/ARHGEF12/NRAS/C5	0.987303481665385
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	2/100	87/9376	2.15540229885057	NRAS/BBC3	1.12412249952997
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	3/100	158/9376	1.78025316455696	TFDP2/E2F2/CDC27	1.02695401827248
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	2/100	90/9376	2.08355555555556	MAP2K3/NRAS	1.07241620147393
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/100	93/9376	2.01634408602151	MAP2K3/NRAS	1.0226884041183
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	3/100	168/9376	1.67428571428571	PIM1/BCL2L1/STAM	0.915632527425513
Environmental Information Processing	Signal transduction	hsa04392	Hippo signaling pathway - multiple species	1/100	29/9376	3.23310344827586	MOB1B	1.25048068506999
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	3/100	170/9376	1.65458823529412	BCL2L1/E2F2/NRAS	0.894257187089405
Metabolism	Glycan biosynthesis and metabolism	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	1/100	30/9376	3.12533333333333	PIGQ	1.21054255448383
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/100	30/9376	3.12533333333333	ABCC4	1.21054255448383
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/100	31/9376	3.02451612903226	RPIA	1.17224314929197
NA	NA	hsa04981	Folate transport and metabolism	1/100	31/9376	3.02451612903226	ABCC4	1.17224314929197
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	3/100	174/9376	1.61655172413793	UBXN6/YOD1/DNAJB2	0.852331019757037
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	2/100	99/9376	1.89414141414141	E2F2/NRAS	0.928592769865785
Metabolism	Carbohydrate metabolism	hsa00052	Galactose metabolism	1/100	32/9376	2.93	HK1	1.13545820124843
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/100	101/9376	1.85663366336634	PIM1/NRAS	0.89867804724679
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	2/100	102/9376	1.83843137254902	CA2/CPA3	0.883973668833634
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	2/100	103/9376	1.82058252427184	SLC1A5/CPA3	0.869432788201363
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	2/100	105/9376	1.78590476190476	BCL2L1/BIRC2	0.84082680342089
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	2/100	105/9376	1.78590476190476	ARHGEF12/NRAS	0.84082680342089
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	2/100	106/9376	1.76905660377358	E2F2/NRAS	0.82675463719122
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	1/100	35/9376	2.67885714285714	HK1	1.03313326943114
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	2/100	108/9376	1.7362962962963	XPO7/NUP153	0.79905513965534
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/100	36/9376	2.60444444444444	ST3GAL1	1.00140040862837
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	2/100	109/9376	1.72036697247706	SLC2A1/OGT	0.785421397386801
Metabolism	Global and overview maps	hsa01250	Biosynthesis of nucleotide sugars	1/100	37/9376	2.53405405405405	HK1	0.970725873289877
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	1/100	38/9376	2.46736842105263	HK1	0.941042635272557
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/100	38/9376	2.46736842105263	PNP	0.941042635272557
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	2/100	116/9376	1.61655172413793	HK1/RPIA	0.693742476071673
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	1/100	41/9376	2.28682926829268	ALAS2	0.857355554010136
Genetic Information Processing	Replication and repair	hsa03440	Homologous recombination	1/100	41/9376	2.28682926829268	UIMC1	0.857355554010136
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/100	42/9376	2.23238095238095	GCDH	0.83107648140361
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/100	119/9376	1.57579831932773	BIRC2/MAP2K3	0.65631753860136
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	2/100	120/9376	1.56266666666667	NRAS/FOXO3	0.644073463056555
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/100	43/9376	2.18046511627907	GCDH	0.805530559483441
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	3/100	204/9376	1.37882352941176	ANK1/ARHGEF12/NRAS	0.567969840273314
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	3/100	205/9376	1.37209756097561	MAP2K3/E2F2/ISG15	0.55928178516174
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/100	122/9376	1.53704918032787	SLC2A1/NRAS	0.619918352996745
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/100	122/9376	1.53704918032787	MAP2K3/NRAS	0.619918352996745
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/100	125/9376	1.50016	NRAS/ORMDL3	0.584487046344725
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	1/100	46/9376	2.03826086956522	PSME4	0.732908652078542
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/100	47/9376	1.99489361702128	HK1	0.709926348733291
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	4/100	300/9376	1.25013333333333	PPM1A/MAP2K3/NRAS/MKNK2	0.457183157385534
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/100	48/9376	1.95333333333333	HK1	0.68750584789266
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	6/100	480/9376	1.172	BCL2L1/OPTN/MAP2K3/PINK1/WIPI2/NRAS	0.40165848579942
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	3/100	216/9376	1.30222222222222	BCL2L1/MAP2K3/NRAS	0.46656354437984
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	1/100	49/9376	1.9134693877551	OGT	0.665619930842265
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/100	50/9376	1.8752	OAT	0.644243245325948
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/100	51/9376	1.83843137254902	CEPT1	0.623352142429872
Human Diseases	Infectious disease: viral	hsa05162	Measles	2/100	136/9376	1.37882352941176	BCL2L1/BBC3	0.462035858937701
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/100	138/9376	1.35884057971015	ARHGEF12/MAP2K3	0.440917546470064
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	3/100	227/9376	1.23911894273128	ARHGEF12/E2F2/NRAS	0.378656455103826
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	2/100	144/9376	1.30222222222222	TCF3/NRAS	0.379459133753588
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	2/100	144/9376	1.30222222222222	WIPI2/OPA1	0.379459133753588
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	3/100	238/9376	1.1818487394958	BCL2L1/FOXO4/NRAS	0.295038346152141
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	2/100	148/9376	1.26702702702703	E2F2/NRAS	0.339967618904503
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	2/100	149/9376	1.25852348993289	AGPAT3/NRAS	0.33026925908146
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/100	60/9376	1.56266666666667	NRAS	0.453959742554558
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/100	60/9376	1.56266666666667	NRAS	0.453959742554558
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	2/100	150/9376	1.25013333333333	E2F2/NRAS	0.320638555450265
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/100	62/9376	1.51225806451613	MAML1	0.420166865125355
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/100	63/9376	1.48825396825397	GCDH	0.403716521974435
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/100	63/9376	1.48825396825397	DDB1	0.403716521974435
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	3/100	248/9376	1.1341935483871	BIRC2/MAP2K3/VPS11	0.22236935159582
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	3/100	250/9376	1.12512	WASHC2C/DNAJC6/STAM	0.208190916021861
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/100	65/9376	1.44246153846154	NRAS	0.371654425261869
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/100	67/9376	1.39940298507463	NRAS	0.340645346750874
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/100	72/9376	1.30222222222222	ISG15	0.267277906013664
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	4/100	362/9376	1.03602209944751	BCL2L1/NRAS/FOXO3/PHLPP2	0.0725721179049348
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/100	75/9376	1.25013333333333	RPIA	0.225809728391812
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/100	76/9376	1.23368421052632	CA2	0.212373321408622
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/100	78/9376	1.20205128205128	PABPC1	0.186045602457857
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/100	78/9376	1.20205128205128	C5	0.186045602457857
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/100	79/9376	1.18683544303797	SLC6A9	0.173143688290252
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/100	181/9376	1.03602209944751	ARHGEF12/MRC2	0.0508086563162508
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	2/100	184/9376	1.01913043478261	ARHGEF12/NRAS	0.0272103427516676
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/100	83/9376	1.12963855421687	OGT	0.123168747405782
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/100	83/9376	1.12963855421687	MPV17L	0.123168747405782
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/100	187/9376	1.0027807486631	BCL2L1/BIRC2	0.0039879865306476
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/100	85/9376	1.10305882352941	PNP	0.0990988652376002
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/100	86/9376	1.09023255813953	NRAS	0.0872790291766398
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/100	86/9376	1.09023255813953	SLC2A1	0.0872790291766398
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	1/100	88/9376	1.06545454545455	C5	0.0640509111590347
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	2/100	193/9376	0.97160621761658	NRAS/FOXO3	-0.0413823243215761
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/100	89/9376	1.05348314606742	NRAS	0.0526355899360566
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	1/100	89/9376	1.05348314606742	TRAK2	0.0526355899360566
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/100	195/9376	0.961641025641026	C5/CLCN3	-0.0562010677506156
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	2/100	196/9376	0.956734693877551	E2F2/NRAS	-0.063555295775644
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/100	91/9376	1.03032967032967	NRAS	0.0301858006839421
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/100	93/9376	1.00817204301075	PDCD10	0.00822305530183992
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/100	93/9376	1.00817204301075	MAML1	0.00822305530183992
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	2/100	205/9376	0.914731707317073	DDB1/NRAS	-0.128162632467583
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/100	98/9376	0.956734693877551	PIP4K2A	-0.0447024064374656
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/100	99/9376	0.947070707070707	MAP2K3	-0.0549686637381012
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/100	99/9376	0.947070707070707	C5	-0.0549686637381012
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/100	99/9376	0.947070707070707	NRAS	-0.0549686637381012
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	1/100	100/9376	0.9376	GYPA	-0.0651342606736047
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/100	101/9376	0.928316831683168	NRAS	-0.0752014454700272
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	2/100	212/9376	0.884528301886792	MAP2K3/NRAS	-0.176565647323198
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/100	103/9376	0.910291262135922	PABPC1	-0.0950492068502201
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	3/100	323/9376	0.870835913312693	PIM1/E2F2/NRAS	-0.245274300952982
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/100	107/9376	0.876261682242991	SLC2A1	-0.133654911722786
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/100	109/9376	0.860183486238532	MAP2K3	-0.152442971168808
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/100	110/9376	0.852363636363636	TFR2	-0.161714440531368
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/100	110/9376	0.852363636363636	CDC27	-0.161714440531368
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	3/100	333/9376	0.844684684684685	NRAS/MAML1/ISG15	-0.299630074490899
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	2/100	227/9376	0.826079295154185	NRAS/FOXO3	-0.275411880020248
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/100	115/9376	0.815304347826087	NRAS	-0.206910208504025
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/100	115/9376	0.815304347826087	NRAS	-0.206910208504025
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/100	115/9376	0.815304347826087	WNK1	-0.206910208504025
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	2/100	235/9376	0.797957446808511	MAP2K3/NRAS	-0.325675578225607
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	2/100	238/9376	0.787899159663865	ISG15/C5	-0.344120510946397
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/100	122/9376	0.768524590163934	NRAS	-0.267193136273323
Organismal Systems	Immune system	hsa04611	Platelet activation	1/100	126/9376	0.744126984126984	ARHGEF12	-0.300223139682712
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	1/100	128/9376	0.7325	PNP	-0.316380806546979
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	2/100	250/9376	0.75008	VPS13A/VPS11	-0.415849374457989
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/100	130/9376	0.721230769230769	NRAS	-0.332311091202731
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/100	133/9376	0.704962406015038	NRAS	-0.355796744419967
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/100	134/9376	0.699701492537313	ARHGEF12	-0.363519622744944
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/100	138/9376	0.679420289855073	CDC27	-0.39390533634563
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/100	139/9376	0.67453237410072	NRAS	-0.401379319694995
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/100	140/9376	0.669714285714286	NRAS	-0.408805861065076
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	2/100	268/9376	0.699701492537313	BCL2L1/PINK1	-0.517862338273857
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/100	143/9376	0.655664335664336	C5	-0.430808115583999
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	1/100	154/9376	0.608831168831169	NRAS	-0.50817969945351
NA	NA	hsa04519	Cadherin signaling	3/100	404/9376	0.696237623762376	MAP2K3/NRAS/MOB1B	-0.648015359514668
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	1/100	155/9376	0.604903225806452	MRC2	-0.514974340560481
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/100	155/9376	0.604903225806452	E2F2	-0.514974340560481
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	1/100	157/9376	0.597197452229299	ADIPOR1	-0.528451817353371
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/100	168/9376	0.558095238095238	BIRC2	-0.600075554696947
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	2/100	308/9376	0.608831168831169	WIPI2/BBC3	-0.724751483678626
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/100	173/9376	0.541965317919075	RSAD2	-0.631338061590656
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/100	191/9376	0.490890052356021	NRAS	-0.738063884197862
NA	NA	hsa04082	Neuroactive ligand signaling	1/100	199/9376	0.471155778894472	SLC6A9	-0.782905246774008
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/100	200/9376	0.4688	ARHGEF12	-0.788409102902169
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	1/100	203/9376	0.461871921182266	BIRC2	-0.804791246392596
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	1/100	205/9376	0.457365853658537	SLC2A1	-0.815607050096906
NA	NA	hsa04382	Cornified envelope formation	1/100	217/9376	0.432073732718894	FURIN	-0.878826332717347
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/100	217/9376	0.432073732718894	NRAS	-0.878826332717347
NA	NA	hsa04081	Hormone signaling	1/100	219/9376	0.428127853881278	ADIPOR1	-0.889098060054175
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/100	226/9376	0.414867256637168	ABCC4	-0.924492393358489
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	2/100	388/9376	0.483298969072165	WIPI2/NRAS	-1.07926707220334
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/100	243/9376	0.385843621399177	SRSF8	-1.00711866061852
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	1/100	275/9376	0.340945454545455	C5	-1.15172400191983
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/100	370/9376	0.253405405405405	C5	-1.52133550233901