ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0032182 ubiquitin-like protein binding 7/195 120/18639 0.0583333333333333 5.57576923076923 0.000270537233067616 0.0927010965300037 GO:0004089 carbonate dehydratase activity 3/195 15/18639 0.2 19.1169230769231 0.00046761494804008 0.0927010965300037 GO:0043130 ubiquitin binding 6/195 100/18639 0.06 5.73507692307692 0.000640543570478302 0.0927010965300037 GO:0070628 proteasome binding 3/195 18/18639 0.166666666666667 15.9307692307692 0.000819453506058514 0.0927010965300037 GO:0030506 ankyrin binding 3/195 19/18639 0.157894736842105 15.0923076923077 0.000965636422187539 0.0927010965300037 GO:0032266 phosphatidylinositol-3-phosphate binding 4/195 48/18639 0.0833333333333333 7.96538461538462 0.00157747193523522 0.126197754818818 GO:0030507 spectrin binding 3/195 26/18639 0.115384615384615 11.0289940828402 0.00245527332595264 0.140542887001327 GO:0051537 2 iron, 2 sulfur cluster binding 3/195 28/18639 0.107142857142857 10.2412087912088 0.0030465637038901 0.140542887001327 GO:0035091 phosphatidylinositol binding 9/195 284/18639 0.0316901408450704 3.02908992416035 0.00309752928367851 0.140542887001327 GO:0031593 polyubiquitin modification-dependent protein binding 4/195 59/18639 0.0677966101694915 6.48031290743155 0.00337500822013898 0.140542887001327 GO:1901981 phosphatidylinositol phosphate binding 7/195 185/18639 0.0378378378378378 3.61671517671518 0.00338445663067056 0.140542887001327 GO:0046943 carboxylic acid transmembrane transporter activity 7/195 188/18639 0.0372340425531915 3.55900163666121 0.00369733575487588 0.140542887001327 GO:0005342 organic acid transmembrane transporter activity 7/195 189/18639 0.037037037037037 3.54017094017094 0.00380636985628594 0.140542887001327 GO:0008519 ammonium channel activity 2/195 10/18639 0.2 19.1169230769231 0.00463689963649198 0.148380788367743 GO:0031720 haptoglobin binding 2/195 10/18639 0.2 19.1169230769231 0.00463689963649198 0.148380788367743 GO:0008028 monocarboxylic acid transmembrane transporter activity 4/195 70/18639 0.0571428571428571 5.46197802197802 0.00622141784373647 0.182451551914712 GO:0005200 structural constituent of cytoskeleton 5/195 112/18639 0.0446428571428571 4.26717032967033 0.00647851362345334 0.182451551914712 GO:0008514 organic anion transmembrane transporter activity 8/195 269/18639 0.0297397769516729 2.8426651415499 0.00752203402618916 0.182451551914712 GO:0051536 iron-sulfur cluster binding 4/195 76/18639 0.0526315789473684 5.03076923076923 0.00829489794165532 0.182451551914712 GO:0051540 metal cluster binding 4/195 77/18639 0.051948051948052 4.96543456543457 0.00867934892593096 0.182451551914712 GO:0015175 neutral L-amino acid transmembrane transporter activity 3/195 41/18639 0.0731707317073171 6.99399624765478 0.00897633358320724 0.182451551914712 GO:0005344 oxygen carrier activity 2/195 14/18639 0.142857142857143 13.6549450549451 0.00912257759573559 0.182451551914712 GO:0008494 translation activator activity 2/195 14/18639 0.142857142857143 13.6549450549451 0.00912257759573559 0.182451551914712 GO:1901612 cardiolipin binding 2/195 14/18639 0.142857142857143 13.6549450549451 0.00912257759573559 0.182451551914712 GO:0015101 organic cation transmembrane transporter activity 4/195 81/18639 0.0493827160493827 4.72022792022792 0.0103331355733353 0.192998959583366 GO:0015556 C4-dicarboxylate transmembrane transporter activity 2/195 15/18639 0.133333333333333 12.7446153846154 0.0104541103107657 0.192998959583366 GO:0005521 lamin binding 2/195 16/18639 0.125 11.9480769230769 0.0118659682515977 0.210950546695071 GO:0043495 protein-membrane adaptor activity 3/195 47/18639 0.0638297872340425 6.10114566284779 0.0130452864612045 0.223633482192078 GO:0042578 phosphoric ester hydrolase activity 9/195 363/18639 0.0247933884297521 2.36986649713922 0.014443807549821 0.231072834998458 GO:0050811 GABA receptor binding 2/195 18/18639 0.111111111111111 10.6205128205128 0.0149234539269838 0.231072834998458 GO:1901611 phosphatidylglycerol binding 2/195 18/18639 0.111111111111111 10.6205128205128 0.0149234539269838 0.231072834998458 GO:0016755 aminoacyltransferase activity 11/195 496/18639 0.0221774193548387 2.11982009925558 0.0155607411994448 0.233411117991671 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/195 19/18639 0.105263157894737 10.0615384615385 0.0165655501040186 0.233866589703792 GO:0140036 ubiquitin-modified protein reader activity 2/195 19/18639 0.105263157894737 10.0615384615385 0.0165655501040186 0.233866589703792 GO:0043024 ribosomal small subunit binding 2/195 20/18639 0.1 9.55846153846154 0.0182809076014235 0.245281249369037 GO:0003713 transcription coactivator activity 7/195 256/18639 0.02734375 2.61364182692308 0.0183960937026778 0.245281249369037 GO:0010314 phosphatidylinositol-5-phosphate binding 2/195 21/18639 0.0952380952380952 9.1032967032967 0.0200678302552593 0.253690365926756 GO:0004842 ubiquitin-protein transferase activity 10/195 449/18639 0.022271714922049 2.12883330477985 0.0200838206358682 0.253690365926756 GO:0016881 acid-amino acid ligase activity 2/195 22/18639 0.0909090909090909 8.68951048951049 0.0219246490538291 0.258632959464609 GO:0140035 ubiquitin-like protein reader activity 2/195 22/18639 0.0909090909090909 8.68951048951049 0.0219246490538291 0.258632959464609 GO:0015171 amino acid transmembrane transporter activity 4/195 102/18639 0.0392156862745098 3.74841628959276 0.022313578285993 0.258632959464609 GO:0005283 amino acid:sodium symporter activity 2/195 23/18639 0.0869565217391304 8.31170568561873 0.0238497217600006 0.258632959464609 GO:0016791 phosphatase activity 7/195 273/18639 0.0256410256410256 2.4508875739645 0.0250713001285016 0.258632959464609 GO:0016836 hydro-lyase activity 3/195 61/18639 0.0491803278688525 4.70088272383354 0.0260467708848665 0.258632959464609 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/195 25/18639 0.08 7.64676923076923 0.0278981915873871 0.258632959464609 GO:1902936 phosphatidylinositol bisphosphate binding 4/195 111/18639 0.036036036036036 3.44449064449064 0.0292754464867283 0.258632959464609 GO:0019787 ubiquitin-like protein transferase activity 10/195 479/18639 0.0208768267223382 1.99550345270596 0.0296198446068321 0.258632959464609 GO:0097602 cullin family protein binding 2/195 26/18639 0.0769230769230769 7.35266272189349 0.0300184347758399 0.258632959464609 GO:0015291 secondary active transmembrane transporter activity 7/195 287/18639 0.024390243902439 2.33133208255159 0.0316895454918066 0.258632959464609 GO:0061630 ubiquitin protein ligase activity 8/195 353/18639 0.0226628895184136 2.1662235781216 0.0326804354562392 0.258632959464609 GO:0016866 intramolecular transferase activity 2/195 28/18639 0.0714285714285714 6.82747252747253 0.0344432432522892 0.258632959464609 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/195 28/18639 0.0714285714285714 6.82747252747253 0.0344432432522892 0.258632959464609 GO:0140030 modification-dependent protein binding 5/195 173/18639 0.0289017341040462 2.76256113828368 0.0355480980701054 0.258632959464609 GO:0005543 phospholipid binding 10/195 497/18639 0.0201207243460765 1.92323169787959 0.036687497330644 0.258632959464609 GO:0005416 amino acid:monoatomic cation symporter activity 2/195 29/18639 0.0689655172413793 6.5920424403183 0.0367448054264809 0.258632959464609 GO:0031624 ubiquitin conjugating enzyme binding 2/195 30/18639 0.0666666666666667 6.37230769230769 0.0391038448183221 0.258632959464609 GO:0043539 protein serine/threonine kinase activator activity 3/195 73/18639 0.0410958904109589 3.92813487881981 0.0411355677317881 0.258632959464609 GO:0005310 dicarboxylic acid transmembrane transporter activity 2/195 31/18639 0.0645161290322581 6.16674937965261 0.0415189203624219 0.258632959464609 GO:0070273 phosphatidylinositol-4-phosphate binding 2/195 31/18639 0.0645161290322581 6.16674937965261 0.0415189203624219 0.258632959464609 GO:0072349 modified amino acid transmembrane transporter activity 2/195 31/18639 0.0645161290322581 6.16674937965261 0.0415189203624219 0.258632959464609 GO:0061659 ubiquitin-like protein ligase activity 8/195 372/18639 0.021505376344086 2.05558312655087 0.0423674432991885 0.258632959464609 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 6/195 243/18639 0.0246913580246914 2.36011396011396 0.042892927230102 0.258632959464609 GO:0042910 xenobiotic transmembrane transporter activity 2/195 32/18639 0.0625 5.97403846153846 0.043988614580827 0.258632959464609 GO:0004676 3-phosphoinositide-dependent protein kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:0004711 ribosomal protein S6 kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:0035175 histone H3S10 kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:0035979 histone H2AXS139 kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:0044022 histone H3S28 kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:0044023 histone H4S1 kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:0044024 histone H2AS1 kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:0044025 histone H2BS14 kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:0072354 histone H3T3 kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:0072371 histone H2AS121 kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:0072518 Rho-dependent protein serine/threonine kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:0140823 histone H2BS36 kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:0140855 histone H3S57 kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:0140995 histone H2A kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:0140997 histone H4 kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:0140998 histone H2B kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:1990244 histone H2AT120 kinase activity 6/195 245/18639 0.0244897959183673 2.34084772370487 0.0443313012140914 0.258632959464609 GO:0004677 DNA-dependent protein kinase activity 6/195 246/18639 0.024390243902439 2.33133208255159 0.0450616976705964 0.258632959464609 GO:0140857 histone H3T45 kinase activity 6/195 246/18639 0.024390243902439 2.33133208255159 0.0450616976705964 0.258632959464609 GO:0031490 chromatin DNA binding 4/195 128/18639 0.03125 2.98701923076923 0.0455864085650475 0.258632959464609 GO:0035402 histone H3T11 kinase activity 6/195 247/18639 0.0242914979757085 2.32189349112426 0.0457995865718578 0.258632959464609 GO:0035403 histone H3T6 kinase activity 6/195 247/18639 0.0242914979757085 2.32189349112426 0.0457995865718578 0.258632959464609 GO:0004679 AMP-activated protein kinase activity 6/195 248/18639 0.0241935483870968 2.31253101736973 0.046544981745111 0.259785944623875 GO:0019825 oxygen binding 2/195 34/18639 0.0588235294117647 5.62262443438914 0.0490863050805271 0.270820993547736 GO:0016835 carbon-oxygen lyase activity 3/195 79/18639 0.0379746835443038 3.62979552093476 0.0500100196057188 0.272764385301092 GO:0022804 active transmembrane transporter activity 9/195 457/18639 0.0196936542669584 1.88241036862481 0.0515322293024647 0.272764385301092 GO:0005343 organic acid:sodium symporter activity 2/195 35/18639 0.0571428571428571 5.46197802197802 0.0517115813799987 0.272764385301092 GO:0061631 ubiquitin conjugating enzyme activity 2/195 35/18639 0.0571428571428571 5.46197802197802 0.0517115813799987 0.272764385301092 GO:0015297 antiporter activity 4/195 135/18639 0.0296296296296296 2.83213675213675 0.0535151077842884 0.279209258004983 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/195 36/18639 0.0555555555555556 5.31025641025641 0.0543860357481848 0.280702119990631 GO:0030295 protein kinase activator activity 4/195 139/18639 0.0287769784172662 2.75063641394577 0.0583610546491732 0.298013896080884 GO:0042887 amide transmembrane transporter activity 2/195 38/18639 0.0526315789473684 5.03076923076923 0.0598772826326638 0.302537849091354 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 3/195 86/18639 0.0348837209302326 3.33434704830054 0.0614361309076168 0.307180654538084 GO:0015293 symporter activity 4/195 146/18639 0.0273972602739726 2.61875658587987 0.0673860379370557 0.331884001491261 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 2/195 41/18639 0.0487804878048781 4.66266416510319 0.0684510753075726 0.331884001491261 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/195 41/18639 0.0487804878048781 4.66266416510319 0.0684510753075726 0.331884001491261 GO:0019209 kinase activator activity 4/195 148/18639 0.027027027027027 2.58336798336798 0.0700903039333424 0.336433458880044 GO:0005506 iron ion binding 4/195 154/18639 0.025974025974026 2.48271728271728 0.0785322810330014 0.37227897716028 GO:0141003 histone H2AX kinase activity 7/195 354/18639 0.019774011299435 1.89009126466754 0.0791092826465595 0.37227897716028 GO:0042605 peptide antigen binding 2/195 45/18639 0.0444444444444444 4.24820512820513 0.0804609156083477 0.374963490213659 GO:0140996 histone H3 kinase activity 7/195 357/18639 0.0196078431372549 1.87420814479638 0.08187274429012 0.377874204415938 GO:0035173 histone kinase activity 7/195 360/18639 0.0194444444444444 1.85858974358974 0.0846915772484176 0.380644410634294 GO:0004674 protein serine/threonine kinase activity 8/195 433/18639 0.0184757505773672 1.76599751287973 0.0855589499482491 0.380644410634294 GO:0106310 protein serine kinase activity 7/195 361/18639 0.0193905817174515 1.85344129554656 0.0856434707434749 0.380644410634294 GO:0140359 ABC-type transporter activity 2/195 47/18639 0.0425531914893617 4.06743044189853 0.0866928193340271 0.380644410634294 GO:0061134 peptidase regulator activity 5/195 226/18639 0.0221238938053097 2.11470388019061 0.0891755256318685 0.380644410634294 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/195 48/18639 0.0416666666666667 3.98269230769231 0.0898616459385674 0.380644410634294 GO:0140693 molecular condensate scaffold activity 2/195 48/18639 0.0416666666666667 3.98269230769231 0.0898616459385674 0.380644410634294 GO:0000287 magnesium ion binding 5/195 230/18639 0.0217391304347826 2.07792642140468 0.0943431519625991 0.380644410634294 GO:0005085 guanyl-nucleotide exchange factor activity 5/195 230/18639 0.0217391304347826 2.07792642140468 0.0943431519625991 0.380644410634294 GO:0015103 inorganic anion transmembrane transporter activity 4/195 165/18639 0.0242424242424242 2.3172027972028 0.0952553300752616 0.380644410634294 GO:0008190 eukaryotic initiation factor 4E binding 1/195 10/18639 0.1 9.55846153846154 0.0998519129162981 0.380644410634294 GO:0015187 glycine transmembrane transporter activity 1/195 10/18639 0.1 9.55846153846154 0.0998519129162981 0.380644410634294 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/195 10/18639 0.1 9.55846153846154 0.0998519129162981 0.380644410634294 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/195 10/18639 0.1 9.55846153846154 0.0998519129162981 0.380644410634294 GO:0016868 intramolecular phosphotransferase activity 1/195 10/18639 0.1 9.55846153846154 0.0998519129162981 0.380644410634294 GO:0043121 neurotrophin binding 1/195 10/18639 0.1 9.55846153846154 0.0998519129162981 0.380644410634294 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/195 10/18639 0.1 9.55846153846154 0.0998519129162981 0.380644410634294 GO:0043422 protein kinase B binding 1/195 10/18639 0.1 9.55846153846154 0.0998519129162981 0.380644410634294 GO:0070513 death domain binding 1/195 10/18639 0.1 9.55846153846154 0.0998519129162981 0.380644410634294 GO:0140135 mechanosensitive monoatomic cation channel activity 1/195 10/18639 0.1 9.55846153846154 0.0998519129162981 0.380644410634294 GO:1905394 retromer complex binding 1/195 10/18639 0.1 9.55846153846154 0.0998519129162981 0.380644410634294 GO:0008013 beta-catenin binding 3/195 106/18639 0.0283018867924528 2.70522496371553 0.0999191577915022 0.380644410634294 GO:0004843 cysteine-type deubiquitinase activity 3/195 108/18639 0.0277777777777778 2.65512820512821 0.104199487015642 0.383060428869021 GO:0005225 volume-sensitive anion channel activity 1/195 11/18639 0.0909090909090909 8.68951048951049 0.109274258559184 0.383060428869021 GO:0005536 D-glucose binding 1/195 11/18639 0.0909090909090909 8.68951048951049 0.109274258559184 0.383060428869021 GO:0015173 aromatic amino acid transmembrane transporter activity 1/195 11/18639 0.0909090909090909 8.68951048951049 0.109274258559184 0.383060428869021 GO:0032050 clathrin heavy chain binding 1/195 11/18639 0.0909090909090909 8.68951048951049 0.109274258559184 0.383060428869021 GO:0032794 GTPase activating protein binding 1/195 11/18639 0.0909090909090909 8.68951048951049 0.109274258559184 0.383060428869021 GO:0004721 phosphoprotein phosphatase activity 4/195 175/18639 0.0228571428571429 2.18479120879121 0.111789107997957 0.383060428869021 GO:0030170 pyridoxal phosphate binding 2/195 56/18639 0.0357142857142857 3.41373626373626 0.116344362913651 0.383060428869021 GO:0170055 lipid transmembrane transporter activity 2/195 56/18639 0.0357142857142857 3.41373626373626 0.116344362913651 0.383060428869021 GO:0000340 RNA 7-methylguanosine cap binding 1/195 12/18639 0.0833333333333333 7.96538461538462 0.118598475843968 0.383060428869021 GO:0003995 acyl-CoA dehydrogenase activity 1/195 12/18639 0.0833333333333333 7.96538461538462 0.118598475843968 0.383060428869021 GO:0005049 nuclear export signal receptor activity 1/195 12/18639 0.0833333333333333 7.96538461538462 0.118598475843968 0.383060428869021 GO:0005247 voltage-gated chloride channel activity 1/195 12/18639 0.0833333333333333 7.96538461538462 0.118598475843968 0.383060428869021 GO:0015132 prostaglandin transmembrane transporter activity 1/195 12/18639 0.0833333333333333 7.96538461538462 0.118598475843968 0.383060428869021 GO:0042301 phosphate ion binding 1/195 12/18639 0.0833333333333333 7.96538461538462 0.118598475843968 0.383060428869021 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/195 12/18639 0.0833333333333333 7.96538461538462 0.118598475843968 0.383060428869021 GO:0070679 inositol 1,4,5 trisphosphate binding 1/195 12/18639 0.0833333333333333 7.96538461538462 0.118598475843968 0.383060428869021 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/195 12/18639 0.0833333333333333 7.96538461538462 0.118598475843968 0.383060428869021 GO:0140900 chloride:bicarbonate antiporter activity 1/195 12/18639 0.0833333333333333 7.96538461538462 0.118598475843968 0.383060428869021 GO:1990817 poly(A) RNA polymerase activity 1/195 12/18639 0.0833333333333333 7.96538461538462 0.118598475843968 0.383060428869021 GO:0101005 deubiquitinase activity 3/195 115/18639 0.0260869565217391 2.49351170568562 0.119731127584439 0.383060428869021 GO:0004601 peroxidase activity 2/195 57/18639 0.0350877192982456 3.35384615384615 0.119781450448564 0.383060428869021 GO:0016504 peptidase activator activity 2/195 57/18639 0.0350877192982456 3.35384615384615 0.119781450448564 0.383060428869021 GO:0070279 vitamin B6 binding 2/195 57/18639 0.0350877192982456 3.35384615384615 0.119781450448564 0.383060428869021 GO:0016853 isomerase activity 4/195 180/18639 0.0222222222222222 2.12410256410256 0.120504426581713 0.383060428869021 GO:0015294 solute:monoatomic cation symporter activity 3/195 116/18639 0.0258620689655172 2.47201591511936 0.122016724231697 0.384882179406279 GO:0044389 ubiquitin-like protein ligase binding 6/195 322/18639 0.0186335403726708 1.78107978977544 0.122681194685751 0.384882179406279 GO:0001786 phosphatidylserine binding 2/195 59/18639 0.0338983050847458 3.24015645371578 0.126729853007092 0.385888547949734 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/195 59/18639 0.0338983050847458 3.24015645371578 0.126729853007092 0.385888547949734 GO:0035673 oligopeptide transmembrane transporter activity 1/195 13/18639 0.0769230769230769 7.35266272189349 0.127825581508349 0.385888547949734 GO:0039706 co-receptor binding 1/195 13/18639 0.0769230769230769 7.35266272189349 0.127825581508349 0.385888547949734 GO:0071714 icosanoid transmembrane transporter activity 1/195 13/18639 0.0769230769230769 7.35266272189349 0.127825581508349 0.385888547949734 GO:0097157 pre-mRNA intronic binding 1/195 13/18639 0.0769230769230769 7.35266272189349 0.127825581508349 0.385888547949734 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/195 60/18639 0.0333333333333333 3.18615384615385 0.13023939798496 0.390035125486053 GO:0008234 cysteine-type peptidase activity 4/195 187/18639 0.0213903743315508 2.04459070341423 0.133179798616658 0.390035125486053 GO:0015108 chloride transmembrane transporter activity 3/195 121/18639 0.0247933884297521 2.36986649713922 0.133679831986286 0.390035125486053 GO:0019905 syntaxin binding 2/195 61/18639 0.0327868852459016 3.13392181588903 0.133771351445981 0.390035125486053 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/195 122/18639 0.0245901639344262 2.35044136191677 0.136057815364941 0.390035125486053 GO:0005545 1-phosphatidylinositol binding 1/195 14/18639 0.0714285714285714 6.82747252747253 0.136956581809319 0.390035125486053 GO:0008195 phosphatidate phosphatase activity 1/195 14/18639 0.0714285714285714 6.82747252747253 0.136956581809319 0.390035125486053 GO:0008559 ABC-type xenobiotic transporter activity 1/195 14/18639 0.0714285714285714 6.82747252747253 0.136956581809319 0.390035125486053 GO:0046030 inositol trisphosphate phosphatase activity 1/195 14/18639 0.0714285714285714 6.82747252747253 0.136956581809319 0.390035125486053 GO:0015179 L-amino acid transmembrane transporter activity 2/195 62/18639 0.032258064516129 3.0833746898263 0.137324867098215 0.390035125486053 GO:0031386 protein tag activity 1/195 15/18639 0.0666666666666667 6.37230769230769 0.145992472630645 0.40043649635834 GO:0045504 dynein heavy chain binding 1/195 15/18639 0.0666666666666667 6.37230769230769 0.145992472630645 0.40043649635834 GO:0061578 K63-linked deubiquitinase activity 1/195 15/18639 0.0666666666666667 6.37230769230769 0.145992472630645 0.40043649635834 GO:0120283 protein serine/threonine kinase binding 1/195 15/18639 0.0666666666666667 6.37230769230769 0.145992472630645 0.40043649635834 GO:0140161 monocarboxylate:sodium symporter activity 1/195 15/18639 0.0666666666666667 6.37230769230769 0.145992472630645 0.40043649635834 GO:0141047 molecular tag activity 1/195 15/18639 0.0666666666666667 6.37230769230769 0.145992472630645 0.40043649635834 GO:0019783 ubiquitin-like protein peptidase activity 3/195 127/18639 0.0236220472440945 2.25790430042399 0.148161444168702 0.403640283410146 GO:0003712 transcription coregulator activity 8/195 495/18639 0.0161616161616162 1.54480186480186 0.148842354507491 0.403640283410146 GO:0000062 fatty-acyl-CoA binding 1/195 16/18639 0.0625 5.97403846153846 0.154934239589248 0.406384890725896 GO:0004708 MAP kinase kinase activity 1/195 16/18639 0.0625 5.97403846153846 0.154934239589248 0.406384890725896 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/195 16/18639 0.0625 5.97403846153846 0.154934239589248 0.406384890725896 GO:0015378 sodium:chloride symporter activity 1/195 16/18639 0.0625 5.97403846153846 0.154934239589248 0.406384890725896 GO:0015562 efflux transmembrane transporter activity 1/195 16/18639 0.0625 5.97403846153846 0.154934239589248 0.406384890725896 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/195 16/18639 0.0625 5.97403846153846 0.154934239589248 0.406384890725896 GO:0016829 lyase activity 4/195 200/18639 0.02 1.91169230769231 0.158078974009464 0.412379932198603 GO:0030145 manganese ion binding 2/195 68/18639 0.0294117647058824 2.81131221719457 0.15905324818151 0.412678697984459 GO:1901567 fatty acid derivative binding 1/195 17/18639 0.0588235294117647 5.62262443438914 0.163782858140507 0.422665440362598 GO:0140789 histone phosphatase activity 3/195 136/18639 0.0220588235294118 2.10848416289593 0.17077067323173 0.424649684377783 GO:0005372 water transmembrane transporter activity 1/195 18/18639 0.0555555555555556 5.31025641025641 0.172539293682479 0.424649684377783 GO:0008308 voltage-gated monoatomic anion channel activity 1/195 18/18639 0.0555555555555556 5.31025641025641 0.172539293682479 0.424649684377783 GO:0015172 acidic amino acid transmembrane transporter activity 1/195 18/18639 0.0555555555555556 5.31025641025641 0.172539293682479 0.424649684377783 GO:0015373 monoatomic anion:sodium symporter activity 1/195 18/18639 0.0555555555555556 5.31025641025641 0.172539293682479 0.424649684377783 GO:0017075 syntaxin-1 binding 1/195 18/18639 0.0555555555555556 5.31025641025641 0.172539293682479 0.424649684377783 GO:0051015 actin filament binding 4/195 209/18639 0.0191387559808612 1.82937062937063 0.176251580157835 0.424649684377783 GO:0140767 enzyme-substrate adaptor activity 3/195 139/18639 0.0215827338129496 2.06297731045932 0.178518039497165 0.424649684377783 GO:0008301 DNA binding, bending 1/195 19/18639 0.0526315789473684 5.03076923076923 0.181204501659059 0.424649684377783 GO:0008381 mechanosensitive monoatomic ion channel activity 1/195 19/18639 0.0526315789473684 5.03076923076923 0.181204501659059 0.424649684377783 GO:0015245 fatty acid transmembrane transporter activity 1/195 19/18639 0.0526315789473684 5.03076923076923 0.181204501659059 0.424649684377783 GO:0022840 leak channel activity 1/195 19/18639 0.0526315789473684 5.03076923076923 0.181204501659059 0.424649684377783 GO:0022842 narrow pore channel activity 1/195 19/18639 0.0526315789473684 5.03076923076923 0.181204501659059 0.424649684377783 GO:0042577 lipid phosphatase activity 1/195 19/18639 0.0526315789473684 5.03076923076923 0.181204501659059 0.424649684377783 GO:0042834 peptidoglycan binding 1/195 19/18639 0.0526315789473684 5.03076923076923 0.181204501659059 0.424649684377783 GO:0120227 acyl-CoA binding 1/195 19/18639 0.0526315789473684 5.03076923076923 0.181204501659059 0.424649684377783 GO:1990380 K48-linked deubiquitinase activity 1/195 19/18639 0.0526315789473684 5.03076923076923 0.181204501659059 0.424649684377783 GO:0003684 damaged DNA binding 2/195 74/18639 0.027027027027027 2.58336798336798 0.181360802703012 0.424649684377783 GO:0048029 monosaccharide binding 2/195 74/18639 0.027027027027027 2.58336798336798 0.181360802703012 0.424649684377783 GO:0003725 double-stranded RNA binding 2/195 75/18639 0.0266666666666667 2.54892307692308 0.18512418691417 0.430255199199308 GO:0020037 heme binding 3/195 142/18639 0.0211267605633803 2.01939328277356 0.186360372206922 0.430255199199308 GO:0000339 RNA cap binding 1/195 20/18639 0.05 4.77923076923077 0.189779427662093 0.430255199199308 GO:0052745 inositol phosphate phosphatase activity 1/195 20/18639 0.05 4.77923076923077 0.189779427662093 0.430255199199308 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/195 21/18639 0.0476190476190476 4.55164835164835 0.198265007532435 0.430255199199308 GO:0008373 sialyltransferase activity 1/195 21/18639 0.0476190476190476 4.55164835164835 0.198265007532435 0.430255199199308 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/195 21/18639 0.0476190476190476 4.55164835164835 0.198265007532435 0.430255199199308 GO:0015125 bile acid transmembrane transporter activity 1/195 21/18639 0.0476190476190476 4.55164835164835 0.198265007532435 0.430255199199308 GO:0019200 carbohydrate kinase activity 1/195 21/18639 0.0476190476190476 4.55164835164835 0.198265007532435 0.430255199199308 GO:0035613 RNA stem-loop binding 1/195 21/18639 0.0476190476190476 4.55164835164835 0.198265007532435 0.430255199199308 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/195 21/18639 0.0476190476190476 4.55164835164835 0.198265007532435 0.430255199199308 GO:0015370 solute:sodium symporter activity 2/195 79/18639 0.0253164556962025 2.41986368062317 0.200283384784813 0.430255199199308 GO:0008509 monoatomic anion transmembrane transporter activity 3/195 149/18639 0.0201342281879195 1.92452245740836 0.204993672747614 0.430255199199308 GO:0008093 cytoskeletal anchor activity 1/195 22/18639 0.0454545454545455 4.34475524475524 0.206662167459988 0.430255199199308 GO:0015377 chloride:monoatomic cation symporter activity 1/195 22/18639 0.0454545454545455 4.34475524475524 0.206662167459988 0.430255199199308 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/195 22/18639 0.0454545454545455 4.34475524475524 0.206662167459988 0.430255199199308 GO:0001618 virus receptor activity 2/195 81/18639 0.0246913580246914 2.36011396011396 0.207917687065048 0.430255199199308 GO:0033192 calmodulin-dependent protein phosphatase activity 2/195 81/18639 0.0246913580246914 2.36011396011396 0.207917687065048 0.430255199199308 GO:0140791 histone H2AXS140 phosphatase activity 2/195 81/18639 0.0246913580246914 2.36011396011396 0.207917687065048 0.430255199199308 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/195 81/18639 0.0246913580246914 2.36011396011396 0.207917687065048 0.430255199199308 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/195 81/18639 0.0246913580246914 2.36011396011396 0.207917687065048 0.430255199199308 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/195 81/18639 0.0246913580246914 2.36011396011396 0.207917687065048 0.430255199199308 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/195 81/18639 0.0246913580246914 2.36011396011396 0.207917687065048 0.430255199199308 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/195 81/18639 0.0246913580246914 2.36011396011396 0.207917687065048 0.430255199199308 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/195 81/18639 0.0246913580246914 2.36011396011396 0.207917687065048 0.430255199199308 GO:0031625 ubiquitin protein ligase binding 5/195 302/18639 0.0165562913907285 1.5825267447784 0.210192507739374 0.430255199199308 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/195 82/18639 0.024390243902439 2.33133208255159 0.211746422495302 0.430255199199308 GO:0033549 MAP kinase phosphatase activity 2/195 82/18639 0.024390243902439 2.33133208255159 0.211746422495302 0.430255199199308 GO:0140272 exogenous protein binding 2/195 82/18639 0.024390243902439 2.33133208255159 0.211746422495302 0.430255199199308 GO:0046906 tetrapyrrole binding 3/195 152/18639 0.0197368421052632 1.88653846153846 0.213108077509055 0.430255199199308 GO:0005212 structural constituent of eye lens 1/195 23/18639 0.0434782608695652 4.15585284280936 0.214971824082714 0.430255199199308 GO:0042171 lysophosphatidic acid acyltransferase activity 1/195 23/18639 0.0434782608695652 4.15585284280936 0.214971824082714 0.430255199199308 GO:0070577 lysine-acetylated histone binding 1/195 23/18639 0.0434782608695652 4.15585284280936 0.214971824082714 0.430255199199308 GO:0071617 lysophospholipid acyltransferase activity 1/195 23/18639 0.0434782608695652 4.15585284280936 0.214971824082714 0.430255199199308 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/195 83/18639 0.0240963855421687 2.3032437442076 0.21558211432114 0.430255199199308 GO:0017018 myosin phosphatase activity 2/195 84/18639 0.0238095238095238 2.27582417582418 0.21942420152114 0.430255199199308 GO:0051117 ATPase binding 2/195 84/18639 0.0238095238095238 2.27582417582418 0.21942420152114 0.430255199199308 GO:0004622 lysophospholipase activity 1/195 24/18639 0.0416666666666667 3.98269230769231 0.223194884584641 0.430255199199308 GO:0015149 hexose transmembrane transporter activity 1/195 24/18639 0.0416666666666667 3.98269230769231 0.223194884584641 0.430255199199308 GO:0015295 solute:proton symporter activity 1/195 24/18639 0.0416666666666667 3.98269230769231 0.223194884584641 0.430255199199308 GO:0048027 mRNA 5'-UTR binding 1/195 24/18639 0.0416666666666667 3.98269230769231 0.223194884584641 0.430255199199308 GO:0055056 D-glucose transmembrane transporter activity 1/195 24/18639 0.0416666666666667 3.98269230769231 0.223194884584641 0.430255199199308 GO:0070300 phosphatidic acid binding 1/195 24/18639 0.0416666666666667 3.98269230769231 0.223194884584641 0.430255199199308 GO:0140033 acetylation-dependent protein binding 1/195 24/18639 0.0416666666666667 3.98269230769231 0.223194884584641 0.430255199199308 GO:0016209 antioxidant activity 2/195 86/18639 0.0232558139534884 2.22289803220036 0.227125372103 0.433602655287923 GO:0008081 phosphoric diester hydrolase activity 2/195 87/18639 0.0229885057471264 2.1973474801061 0.230983387097686 0.433602655287923 GO:0008139 nuclear localization sequence binding 1/195 25/18639 0.04 3.82338461538462 0.23133224679286 0.433602655287923 GO:0008483 transaminase activity 1/195 25/18639 0.04 3.82338461538462 0.23133224679286 0.433602655287923 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/195 25/18639 0.04 3.82338461538462 0.23133224679286 0.433602655287923 GO:0017056 structural constituent of nuclear pore 1/195 25/18639 0.04 3.82338461538462 0.23133224679286 0.433602655287923 GO:0004866 endopeptidase inhibitor activity 3/195 161/18639 0.0186335403726708 1.78107978977544 0.237839551425685 0.433602655287923 GO:0004435 phosphatidylinositol phospholipase C activity 1/195 26/18639 0.0384615384615385 3.67633136094675 0.239384799273541 0.433602655287923 GO:0005227 calcium-activated cation channel activity 1/195 26/18639 0.0384615384615385 3.67633136094675 0.239384799273541 0.433602655287923 GO:0008143 poly(A) binding 1/195 26/18639 0.0384615384615385 3.67633136094675 0.239384799273541 0.433602655287923 GO:0008198 ferrous iron binding 1/195 26/18639 0.0384615384615385 3.67633136094675 0.239384799273541 0.433602655287923 GO:0015145 monosaccharide transmembrane transporter activity 1/195 26/18639 0.0384615384615385 3.67633136094675 0.239384799273541 0.433602655287923 GO:0015216 purine nucleotide transmembrane transporter activity 1/195 26/18639 0.0384615384615385 3.67633136094675 0.239384799273541 0.433602655287923 GO:0050681 nuclear androgen receptor binding 1/195 26/18639 0.0384615384615385 3.67633136094675 0.239384799273541 0.433602655287923 GO:0052742 phosphatidylinositol kinase activity 1/195 26/18639 0.0384615384615385 3.67633136094675 0.239384799273541 0.433602655287923 GO:0070412 R-SMAD binding 1/195 26/18639 0.0384615384615385 3.67633136094675 0.239384799273541 0.433602655287923 GO:0072341 modified amino acid binding 2/195 91/18639 0.021978021978022 2.10076077768385 0.246452996739581 0.441374134888262 GO:0001671 ATPase activator activity 1/195 27/18639 0.037037037037037 3.54017094017094 0.247353421426964 0.441374134888262 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/195 27/18639 0.037037037037037 3.54017094017094 0.247353421426964 0.441374134888262 GO:0008266 poly(U) RNA binding 1/195 27/18639 0.037037037037037 3.54017094017094 0.247353421426964 0.441374134888262 GO:0043178 alcohol binding 2/195 92/18639 0.0217391304347826 2.07792642140468 0.250327319715136 0.443384182521275 GO:0052689 carboxylic ester hydrolase activity 2/195 92/18639 0.0217391304347826 2.07792642140468 0.250327319715136 0.443384182521275 GO:0030695 GTPase regulator activity 7/195 489/18639 0.0143149284253579 1.36828692779613 0.252448712406724 0.445497727776572 GO:0060589 nucleoside-triphosphatase regulator activity 7/195 490/18639 0.0142857142857143 1.36549450549451 0.254034229111254 0.446653589646161 GO:0051119 sugar transmembrane transporter activity 1/195 28/18639 0.0357142857142857 3.41373626373626 0.255238983581581 0.447133985836347 GO:0030414 peptidase inhibitor activity 3/195 169/18639 0.0177514792899408 1.69676832043696 0.260216322151109 0.449419289500172 GO:0004867 serine-type endopeptidase inhibitor activity 2/195 95/18639 0.0210526315789474 2.01230769230769 0.261959354418724 0.449419289500172 GO:0004181 metallocarboxypeptidase activity 1/195 29/18639 0.0344827586206897 3.29602122015915 0.26304234708712 0.449419289500172 GO:0004629 phospholipase C activity 1/195 29/18639 0.0344827586206897 3.29602122015915 0.26304234708712 0.449419289500172 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/195 29/18639 0.0344827586206897 3.29602122015915 0.26304234708712 0.449419289500172 GO:0106222 lncRNA binding 1/195 29/18639 0.0344827586206897 3.29602122015915 0.26304234708712 0.449419289500172 GO:0042277 peptide binding 4/195 249/18639 0.0160642570281124 1.53549582947173 0.264033832581351 0.449419289500172 GO:0140104 molecular carrier activity 4/195 249/18639 0.0160642570281124 1.53549582947173 0.264033832581351 0.449419289500172 GO:0008187 poly-pyrimidine tract binding 1/195 30/18639 0.0333333333333333 3.18615384615385 0.270764364406734 0.452846323746455 GO:0015215 nucleotide transmembrane transporter activity 1/195 30/18639 0.0333333333333333 3.18615384615385 0.270764364406734 0.452846323746455 GO:0016769 transferase activity, transferring nitrogenous groups 1/195 30/18639 0.0333333333333333 3.18615384615385 0.270764364406734 0.452846323746455 GO:0022839 monoatomic ion-gated channel activity 1/195 30/18639 0.0333333333333333 3.18615384615385 0.270764364406734 0.452846323746455 GO:0070566 adenylyltransferase activity 1/195 30/18639 0.0333333333333333 3.18615384615385 0.270764364406734 0.452846323746455 GO:0042626 ATPase-coupled transmembrane transporter activity 2/195 98/18639 0.0204081632653061 1.95070643642072 0.273595628478546 0.45599271413091 GO:0019887 protein kinase regulator activity 4/195 255/18639 0.0156862745098039 1.4993665158371 0.277907246110392 0.45922619250839 GO:0005452 solute:inorganic anion antiporter activity 1/195 31/18639 0.032258064516129 3.0833746898263 0.278405879208211 0.45922619250839 GO:0016411 acylglycerol O-acyltransferase activity 1/195 31/18639 0.032258064516129 3.0833746898263 0.278405879208211 0.45922619250839 GO:0015106 bicarbonate transmembrane transporter activity 1/195 32/18639 0.03125 2.98701923076923 0.285967726454256 0.462170062956373 GO:0030515 snoRNA binding 1/195 32/18639 0.03125 2.98701923076923 0.285967726454256 0.462170062956373 GO:0031369 translation initiation factor binding 1/195 32/18639 0.03125 2.98701923076923 0.285967726454256 0.462170062956373 GO:0043425 bHLH transcription factor binding 1/195 32/18639 0.03125 2.98701923076923 0.285967726454256 0.462170062956373 GO:0070717 poly-purine tract binding 1/195 32/18639 0.03125 2.98701923076923 0.285967726454256 0.462170062956373 GO:0140142 nucleocytoplasmic carrier activity 1/195 32/18639 0.03125 2.98701923076923 0.285967726454256 0.462170062956373 GO:0004722 protein serine/threonine phosphatase activity 2/195 103/18639 0.0194174757281553 1.85601194921583 0.29296811991361 0.471894958250109 GO:0015035 protein-disulfide reductase activity 1/195 34/18639 0.0294117647058824 2.81131221719457 0.300855715140673 0.481369144225077 GO:0090482 vitamin transmembrane transporter activity 1/195 34/18639 0.0294117647058824 2.81131221719457 0.300855715140673 0.481369144225077 GO:0061135 endopeptidase regulator activity 3/195 184/18639 0.016304347826087 1.55844481605351 0.302804708272915 0.482877940102987 GO:0000149 SNARE binding 2/195 106/18639 0.0188679245283019 1.80348330914369 0.304561716047556 0.484071601664989 GO:0140566 histone reader activity 1/195 35/18639 0.0285714285714286 2.73098901098901 0.308183483780693 0.488211459454563 GO:0004190 aspartic-type endopeptidase activity 1/195 36/18639 0.0277777777777778 2.65512820512821 0.315434839438764 0.495876049540794 GO:0045505 dynein intermediate chain binding 1/195 36/18639 0.0277777777777778 2.65512820512821 0.315434839438764 0.495876049540794 GO:0004620 phospholipase activity 2/195 109/18639 0.018348623853211 1.75384615384615 0.316120981582256 0.495876049540794 GO:0003779 actin binding 6/195 443/18639 0.0135440180586907 1.29459975690224 0.319090666585185 0.498636850929737 GO:0019902 phosphatase binding 3/195 190/18639 0.0157894736842105 1.50923076923077 0.319958646013248 0.498636850929737 GO:0022829 wide pore channel activity 1/195 37/18639 0.027027027027027 2.58336798336798 0.322610574874417 0.499526051418451 GO:0070001 aspartic-type peptidase activity 1/195 37/18639 0.027027027027027 2.58336798336798 0.322610574874417 0.499526051418451 GO:0043022 ribosome binding 2/195 112/18639 0.0178571428571429 1.70686813186813 0.327636898368662 0.505677528028804 GO:0043531 ADP binding 1/195 38/18639 0.0263157894736842 2.51538461538462 0.329711474664734 0.50724842256113 GO:0017124 SH3 domain binding 2/195 115/18639 0.0173913043478261 1.66234113712375 0.339101035842492 0.517153903762368 GO:0015036 disulfide oxidoreductase activity 1/195 40/18639 0.025 2.38961538461538 0.343691865208741 0.517153903762368 GO:0015144 carbohydrate transmembrane transporter activity 1/195 40/18639 0.025 2.38961538461538 0.343691865208741 0.517153903762368 GO:0030331 nuclear estrogen receptor binding 1/195 40/18639 0.025 2.38961538461538 0.343691865208741 0.517153903762368 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/195 40/18639 0.025 2.38961538461538 0.343691865208741 0.517153903762368 GO:0061791 GTPase motor activity 1/195 40/18639 0.025 2.38961538461538 0.343691865208741 0.517153903762368 GO:1990606 membrane scission GTPase motor activity 1/195 40/18639 0.025 2.38961538461538 0.343691865208741 0.517153903762368 GO:0001727 lipid kinase activity 1/195 41/18639 0.024390243902439 2.33133208255159 0.35057288495627 0.524221136383207 GO:0140318 protein transporter activity 1/195 41/18639 0.024390243902439 2.33133208255159 0.35057288495627 0.524221136383207 GO:0019207 kinase regulator activity 4/195 287/18639 0.0139372822299652 1.33218976145805 0.353327796390438 0.526699820706243 GO:0003697 single-stranded DNA binding 2/195 121/18639 0.0165289256198347 1.57991099809282 0.361843024763064 0.536128103378407 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/195 43/18639 0.0232558139534884 2.22289803220036 0.364120336877835 0.536128103378407 GO:0008200 ion channel inhibitor activity 1/195 43/18639 0.0232558139534884 2.22289803220036 0.364120336877835 0.536128103378407 GO:0008375 acetylglucosaminyltransferase activity 1/195 43/18639 0.0232558139534884 2.22289803220036 0.364120336877835 0.536128103378407 GO:0016248 channel inhibitor activity 1/195 44/18639 0.0227272727272727 2.17237762237762 0.370788251177083 0.542616952942073 GO:0043014 alpha-tubulin binding 1/195 44/18639 0.0227272727272727 2.17237762237762 0.370788251177083 0.542616952942073 GO:0001664 G protein-coupled receptor binding 4/195 297/18639 0.0134680134680135 1.28733488733489 0.377064313468977 0.54561918030757 GO:0008009 chemokine activity 1/195 45/18639 0.0222222222222222 2.12410256410256 0.377386599712736 0.54561918030757 GO:0051539 4 iron, 4 sulfur cluster binding 1/195 45/18639 0.0222222222222222 2.12410256410256 0.377386599712736 0.54561918030757 GO:0141110 transporter inhibitor activity 1/195 45/18639 0.0222222222222222 2.12410256410256 0.377386599712736 0.54561918030757 GO:0004180 carboxypeptidase activity 1/195 46/18639 0.0217391304347826 2.07792642140468 0.38391610455602 0.551735719122424 GO:0030276 clathrin binding 1/195 46/18639 0.0217391304347826 2.07792642140468 0.38391610455602 0.551735719122424 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/195 128/18639 0.015625 1.49350961538462 0.387999238987749 0.55593920810185 GO:0016298 lipase activity 2/195 130/18639 0.0153846153846154 1.4705325443787 0.395387725242963 0.564839607489947 GO:0031072 heat shock protein binding 2/195 131/18639 0.0152671755725191 1.45930710510863 0.399066813732337 0.568403770301252 GO:0016763 pentosyltransferase activity 1/195 49/18639 0.0204081632653061 1.95070643642072 0.403098666256071 0.570759173459924 GO:0060590 ATPase regulator activity 1/195 49/18639 0.0204081632653061 1.95070643642072 0.403098666256071 0.570759173459924 GO:0015605 organophosphate ester transmembrane transporter activity 1/195 50/18639 0.02 1.91169230769231 0.409359869057581 0.577184068056263 GO:0051087 protein-folding chaperone binding 2/195 134/18639 0.0149253731343284 1.42663605051665 0.410041181681637 0.577184068056263 GO:0005048 signal sequence binding 1/195 51/18639 0.0196078431372549 1.87420814479638 0.415555728196522 0.578917752467185 GO:0016597 amino acid binding 1/195 51/18639 0.0196078431372549 1.87420814479638 0.415555728196522 0.578917752467185 GO:0030544 Hsp70 protein binding 1/195 51/18639 0.0196078431372549 1.87420814479638 0.415555728196522 0.578917752467185 GO:0002020 protease binding 2/195 136/18639 0.0147058823529412 1.40565610859729 0.417303213236763 0.578917752467185 GO:0044325 transmembrane transporter binding 2/195 136/18639 0.0147058823529412 1.40565610859729 0.417303213236763 0.578917752467185 GO:0016922 nuclear receptor binding 2/195 137/18639 0.0145985401459854 1.39539584503088 0.420917450613678 0.582248923039094 GO:0016860 intramolecular oxidoreductase activity 1/195 53/18639 0.0188679245283019 1.80348330914369 0.427754122342465 0.588146431631629 GO:0004713 protein tyrosine kinase activity 2/195 140/18639 0.0142857142857143 1.36549450549451 0.431691118660132 0.588146431631629 GO:0003925 G protein activity 1/195 54/18639 0.0185185185185185 1.77008547008547 0.433757993328326 0.588146431631629 GO:0015485 cholesterol binding 1/195 54/18639 0.0185185185185185 1.77008547008547 0.433757993328326 0.588146431631629 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/195 54/18639 0.0185185185185185 1.77008547008547 0.433757993328326 0.588146431631629 GO:0017069 snRNA binding 1/195 54/18639 0.0185185185185185 1.77008547008547 0.433757993328326 0.588146431631629 GO:0140463 chromatin-protein adaptor activity 1/195 54/18639 0.0185185185185185 1.77008547008547 0.433757993328326 0.588146431631629 GO:0008374 O-acyltransferase activity 1/195 55/18639 0.0181818181818182 1.7379020979021 0.439699192752646 0.594522852172591 GO:0019903 protein phosphatase binding 2/195 144/18639 0.0138888888888889 1.3275641025641 0.445889319435255 0.601199082384614 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/195 57/18639 0.0175438596491228 1.67692307692308 0.451396173638213 0.606919225059782 GO:0003924 GTPase activity 4/195 331/18639 0.0120845921450151 1.15510109226121 0.456751176419522 0.612403811959135 GO:0036002 pre-mRNA binding 1/195 59/18639 0.0169491525423729 1.62007822685789 0.462850191609126 0.615424077485819 GO:0070063 RNA polymerase binding 1/195 59/18639 0.0169491525423729 1.62007822685789 0.462850191609126 0.615424077485819 GO:0070888 E-box binding 1/195 59/18639 0.0169491525423729 1.62007822685789 0.462850191609126 0.615424077485819 GO:0019842 vitamin binding 2/195 150/18639 0.0133333333333333 1.27446153846154 0.466811906487521 0.618977113574613 GO:1901682 sulfur compound transmembrane transporter activity 1/195 63/18639 0.0158730158730159 1.51721611721612 0.485049320400331 0.641387531107875 GO:0038024 cargo receptor activity 1/195 65/18639 0.0153846153846154 1.4705325443787 0.495804166017943 0.653807691452233 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 4/195 349/18639 0.0114613180515759 1.09552567776063 0.497621708144462 0.654406629888608 GO:0008235 metalloexopeptidase activity 1/195 66/18639 0.0151515151515152 1.44825174825175 0.501097489353062 0.65717703521713 GO:0016500 protein-hormone receptor activity 1/195 67/18639 0.0149253731343284 1.42663605051665 0.506335522496666 0.662237195635966 GO:0032934 sterol binding 1/195 68/18639 0.0147058823529412 1.40565610859729 0.511518840023758 0.665390361006514 GO:1990841 promoter-specific chromatin binding 1/195 68/18639 0.0147058823529412 1.40565610859729 0.511518840023758 0.665390361006514 GO:0015081 sodium ion transmembrane transporter activity 2/195 164/18639 0.0121951219512195 1.1656660412758 0.513760856330631 0.666500570374873 GO:0003730 mRNA 3'-UTR binding 3/195 262/18639 0.0114503816793893 1.09448032883147 0.518576334400438 0.670934341003262 GO:0015399 primary active transmembrane transporter activity 2/195 166/18639 0.0120481927710843 1.1516218721038 0.520243992530224 0.671282571006741 GO:0016874 ligase activity 2/195 167/18639 0.0119760479041916 1.14472593274988 0.523463997526434 0.673626591991122 GO:0140299 molecular sensor activity 1/195 71/18639 0.0140845070422535 1.34626218851571 0.526746155916584 0.67603784716567 GO:0016757 glycosyltransferase activity 3/195 267/18639 0.0112359550561798 1.07398444252377 0.531309749819096 0.676986192678913 GO:0005518 collagen binding 1/195 72/18639 0.0138888888888889 1.3275641025641 0.531716238833229 0.676986192678913 GO:0042379 chemokine receptor binding 1/195 72/18639 0.0138888888888889 1.3275641025641 0.531716238833229 0.676986192678913 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 3/195 268/18639 0.0111940298507463 1.06997703788749 0.533833987664052 0.677884428779748 GO:0004521 RNA endonuclease activity 1/195 73/18639 0.0136986301369863 1.30937829293994 0.53663439111564 0.679642500621392 GO:0005096 GTPase activator activity 3/195 271/18639 0.011070110701107 1.05813227363043 0.541360904095506 0.683824299910113 GO:0003823 antigen binding 2/195 174/18639 0.0114942528735632 1.09867374005305 0.545596778386689 0.686471695341305 GO:0019003 GDP binding 1/195 75/18639 0.0133333333333333 1.27446153846154 0.546317057542455 0.686471695341305 GO:0017022 myosin binding 1/195 76/18639 0.0131578947368421 1.25769230769231 0.55108263466911 0.690651865903845 GO:0043021 ribonucleoprotein complex binding 2/195 177/18639 0.0112994350282486 1.08005215123859 0.554861747046853 0.693577183808566 GO:0005319 lipid transporter activity 2/195 178/18639 0.0112359550561798 1.07398444252377 0.557920410596882 0.694695122243025 GO:0001217 DNA-binding transcription repressor activity 3/195 278/18639 0.0107913669064748 1.03148865522966 0.558650660803766 0.694695122243025 GO:0005525 GTP binding 4/195 378/18639 0.0105820105820106 1.01147741147741 0.560527261215102 0.695227610809429 GO:0030246 carbohydrate binding 3/195 280/18639 0.0107142857142857 1.02412087912088 0.563518848932058 0.69713672032832 GO:0046332 SMAD binding 1/195 79/18639 0.0126582278481013 1.20993184031159 0.56508260474839 0.697274165242229 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 5/195 484/18639 0.0103305785123967 0.98744437380801 0.573975040416697 0.706430818974397 GO:0140297 DNA-binding transcription factor binding 5/195 488/18639 0.0102459016393443 0.979350567465321 0.581314445023755 0.712153617763424 GO:0005254 chloride channel activity 1/195 83/18639 0.0120481927710843 1.1516218721038 0.583075774543803 0.712153617763424 GO:0030165 PDZ domain binding 1/195 83/18639 0.0120481927710843 1.1516218721038 0.583075774543803 0.712153617763424 GO:0031406 carboxylic acid binding 2/195 187/18639 0.0106951871657754 1.02229535170712 0.584776368678513 0.712345925337677 GO:0001216 DNA-binding transcription activator activity 5/195 491/18639 0.010183299389002 0.973366755444149 0.586775114980307 0.712345925337677 GO:0022834 ligand-gated channel activity 2/195 188/18639 0.0106382978723404 1.01685761047463 0.587685388403584 0.712345925337677 GO:0043177 organic acid binding 2/195 189/18639 0.0105820105820106 1.01147741147741 0.590579372916513 0.714050627203844 GO:0050660 flavin adenine dinucleotide binding 1/195 86/18639 0.0116279069767442 1.11144901610018 0.596082857651484 0.718893898675157 GO:0004197 cysteine-type endopeptidase activity 1/195 88/18639 0.0113636363636364 1.08618881118881 0.60452914906753 0.723191484024521 GO:0019001 guanyl nucleotide binding 4/195 400/18639 0.01 0.955846153846154 0.605313163188825 0.723191484024521 GO:0032561 guanyl ribonucleotide binding 4/195 400/18639 0.01 0.955846153846154 0.605313163188825 0.723191484024521 GO:0003727 single-stranded RNA binding 1/195 89/18639 0.0112359550561798 1.07398444252377 0.608686165720639 0.723191484024521 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/195 89/18639 0.0112359550561798 1.07398444252377 0.608686165720639 0.723191484024521 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/195 89/18639 0.0112359550561798 1.07398444252377 0.608686165720639 0.723191484024521 GO:0140793 histone H2AXY142 phosphatase activity 1/195 90/18639 0.0111111111111111 1.06205128205128 0.612799707374789 0.726281134666416 GO:0051219 phosphoprotein binding 1/195 93/18639 0.010752688172043 1.02779156327543 0.624883982497732 0.738779092608157 GO:0016410 N-acyltransferase activity 1/195 94/18639 0.0106382978723404 1.01685761047463 0.62882810109004 0.739797765988283 GO:0042562 hormone binding 1/195 94/18639 0.0106382978723404 1.01685761047463 0.62882810109004 0.739797765988283 GO:0005516 calmodulin binding 2/195 207/18639 0.00966183574879227 0.923522853957637 0.640101862451425 0.751219789674044 GO:0004725 protein tyrosine phosphatase activity 1/195 98/18639 0.0102040816326531 0.975353218210361 0.644196251587043 0.754180977467758 GO:0022836 gated channel activity 3/195 318/18639 0.00943396226415094 0.901741654571843 0.649594088519937 0.758650030388247 GO:0008238 exopeptidase activity 1/195 102/18639 0.00980392156862745 0.93710407239819 0.658931221246483 0.76768685970464 GO:0005253 monoatomic anion channel activity 1/195 103/18639 0.00970873786407767 0.928005974607916 0.662519094788962 0.769997979415742 GO:0004497 monooxygenase activity 1/195 106/18639 0.00943396226415094 0.901741654571843 0.673058968714813 0.780358224596884 GO:0005496 steroid binding 1/195 108/18639 0.00925925925925926 0.885042735042735 0.67990295546212 0.786393779811609 GO:0045296 cadherin binding 3/195 334/18639 0.00898203592814371 0.858544449562414 0.682048717795743 0.786979289764318 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/195 229/18639 0.00873362445414847 0.834800134363453 0.694116064669234 0.798982520482571 GO:0001221 transcription coregulator binding 1/195 115/18639 0.00869565217391304 0.831170568561873 0.702753575929159 0.803146943919039 GO:0035401 histone H3Y41 kinase activity 1/195 115/18639 0.00869565217391304 0.831170568561873 0.702753575929159 0.803146943919039 GO:0140801 histone H2AXY142 kinase activity 1/195 115/18639 0.00869565217391304 0.831170568561873 0.702753575929159 0.803146943919039 GO:0004540 RNA nuclease activity 1/195 121/18639 0.00826446280991736 0.789955499046408 0.721043240195577 0.819600834482526 GO:0051082 unfolded protein binding 1/195 121/18639 0.00826446280991736 0.789955499046408 0.721043240195577 0.819600834482526 GO:0005539 glycosaminoglycan binding 2/195 242/18639 0.00826446280991736 0.789955499046408 0.722790610961316 0.819600834482526 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/195 122/18639 0.00819672131147541 0.783480453972257 0.723980737126232 0.819600834482526 GO:0042393 histone binding 2/195 247/18639 0.00809716599190283 0.77396449704142 0.733203595934428 0.828088767173001 GO:0004519 endonuclease activity 1/195 127/18639 0.0078740157480315 0.752634766807995 0.738212951732819 0.831789241389092 GO:0005262 calcium channel activity 1/195 131/18639 0.00763358778625954 0.729653552554316 0.749071105740989 0.842047144626872 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/195 132/18639 0.00757575757575758 0.724125874125874 0.751714888666238 0.84304473495279 GO:0016779 nucleotidyltransferase activity 1/195 136/18639 0.00735294117647059 0.702828054298643 0.762015760582478 0.848648642876077 GO:0019838 growth factor binding 1/195 136/18639 0.00735294117647059 0.702828054298643 0.762015760582478 0.848648642876077 GO:0099094 ligand-gated monoatomic cation channel activity 1/195 136/18639 0.00735294117647059 0.702828054298643 0.762015760582478 0.848648642876077 GO:0015631 tubulin binding 3/195 385/18639 0.00779220779220779 0.744815184815185 0.770531769950949 0.85614641105661 GO:0008194 UDP-glycosyltransferase activity 1/195 145/18639 0.00689655172413793 0.65920424403183 0.783664402016166 0.862338796277082 GO:1901681 sulfur compound binding 2/195 275/18639 0.00727272727272727 0.695160839160839 0.785560601577428 0.862338796277082 GO:0008017 microtubule binding 2/195 276/18639 0.0072463768115942 0.692642140468227 0.787252647444153 0.862338796277082 GO:0015085 calcium ion transmembrane transporter activity 1/195 147/18639 0.00680272108843537 0.650235478806907 0.788202540801776 0.862338796277082 GO:0000510 H3-H4 histone complex chaperone activity 1/195 151/18639 0.00662251655629139 0.63301069791136 0.796996625536956 0.862338796277082 GO:0140584 chromatin extrusion motor activity 1/195 151/18639 0.00662251655629139 0.63301069791136 0.796996625536956 0.862338796277082 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/195 151/18639 0.00662251655629139 0.63301069791136 0.796996625536956 0.862338796277082 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/195 151/18639 0.00662251655629139 0.63301069791136 0.796996625536956 0.862338796277082 GO:0031267 small GTPase binding 2/195 283/18639 0.00706713780918728 0.67550964936124 0.798772742003797 0.862338796277082 GO:0015616 DNA translocase activity 1/195 152/18639 0.00657894736842105 0.628846153846154 0.7991377796921 0.862338796277082 GO:0140674 ATP-dependent histone chaperone activity 1/195 152/18639 0.00657894736842105 0.628846153846154 0.7991377796921 0.862338796277082 GO:0004175 endopeptidase activity 3/195 405/18639 0.00740740740740741 0.708034188034188 0.799312354764746 0.862338796277082 GO:0003774 cytoskeletal motor activity 1/195 153/18639 0.0065359477124183 0.62473604826546 0.801256464874122 0.862338796277082 GO:0061775 cohesin loader activity 1/195 153/18639 0.0065359477124183 0.62473604826546 0.801256464874122 0.862338796277082 GO:0140658 ATP-dependent chromatin remodeler activity 1/195 158/18639 0.00632911392405063 0.604965920155794 0.811520981859122 0.867914002018343 GO:0004857 enzyme inhibitor activity 3/195 416/18639 0.00721153846153846 0.689312130177515 0.813821806129405 0.867914002018343 GO:0016887 ATP hydrolysis activity 3/195 417/18639 0.00719424460431655 0.687659103486442 0.815096049876121 0.867914002018343 GO:0003689 DNA clamp loader activity 1/195 160/18639 0.00625 0.597403846153846 0.815477531063068 0.867914002018343 GO:0099106 ion channel regulator activity 1/195 160/18639 0.00625 0.597403846153846 0.815477531063068 0.867914002018343 GO:0005178 integrin binding 1/195 161/18639 0.0062111801242236 0.593693263258481 0.817424707936422 0.868061636746643 GO:0140713 histone chaperone activity 1/195 164/18639 0.00609756097560976 0.582833020637899 0.8231444303651 0.872206018929907 GO:0016247 channel regulator activity 1/195 168/18639 0.00595238095238095 0.568956043956044 0.830494336259874 0.878055685913523 GO:0141108 transporter regulator activity 1/195 170/18639 0.00588235294117647 0.562262443438914 0.834054513277319 0.879881684336512 GO:0008201 heparin binding 1/195 172/18639 0.00581395348837209 0.555724508050089 0.837540290295554 0.88142052792139 GO:0005244 voltage-gated monoatomic ion channel activity 1/195 173/18639 0.00578034682080925 0.552512227656736 0.839255763485155 0.88142052792139 GO:0022832 voltage-gated channel activity 1/195 175/18639 0.00571428571428571 0.546197802197802 0.842632831012246 0.88142052792139 GO:0004252 serine-type endopeptidase activity 1/195 176/18639 0.00568181818181818 0.543094405594406 0.844294800138796 0.88142052792139 GO:0051020 GTPase binding 2/195 315/18639 0.00634920634920635 0.606886446886447 0.844694672591332 0.88142052792139 GO:0005216 monoatomic ion channel activity 3/195 448/18639 0.00669642857142857 0.640075549450549 0.851089151776139 0.884514941486911 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/195 181/18639 0.00552486187845304 0.528091797705057 0.85234632142412 0.884514941486911 GO:0046873 metal ion transmembrane transporter activity 3/195 450/18639 0.00666666666666667 0.637230769230769 0.853188370642583 0.884514941486911 GO:0008237 metallopeptidase activity 1/195 184/18639 0.00543478260869565 0.51948160535117 0.856976978103595 0.885819937893522 GO:0015078 proton transmembrane transporter activity 1/195 185/18639 0.00540540540540541 0.516673596673597 0.85848819399467 0.885819937893522 GO:0015276 ligand-gated monoatomic ion channel activity 1/195 186/18639 0.00537634408602151 0.513895781637717 0.859983523038295 0.885819937893522 GO:0140597 protein carrier chaperone 1/195 188/18639 0.00531914893617021 0.508428805237316 0.862927183496626 0.88694871108861 GO:0140097 catalytic activity, acting on DNA 2/195 336/18639 0.00595238095238095 0.568956043956044 0.86945795263664 0.891607204587344 GO:0008236 serine-type peptidase activity 1/195 194/18639 0.00515463917525773 0.492704203013481 0.871393809540495 0.891607204587344 GO:0005261 monoatomic cation channel activity 2/195 341/18639 0.00586510263929619 0.560613579968419 0.874796304342556 0.891607204587344 GO:0016758 hexosyltransferase activity 1/195 197/18639 0.0050761421319797 0.485201093322921 0.875429919030515 0.891607204587344 GO:0017171 serine hydrolase activity 1/195 198/18639 0.00505050505050505 0.482750582750583 0.876747084510889 0.891607204587344 GO:0045182 translation regulator activity 2/195 356/18639 0.00561797752808989 0.536992221261884 0.889632377926256 0.90089701541079 GO:0004518 nuclease activity 1/195 209/18639 0.00478468899521531 0.457342657342657 0.890352538291736 0.90089701541079 GO:0008094 ATP-dependent activity, acting on DNA 1/195 210/18639 0.00476190476190476 0.455164835164835 0.891512671500261 0.90089701541079 GO:0005125 cytokine activity 1/195 234/18639 0.00427350427350427 0.408481262327416 0.915970122976882 0.923667350901057 GO:0033218 amide binding 1/195 247/18639 0.00404858299595142 0.38698224852071 0.92683933877032 0.932668517001579 GO:0005126 cytokine receptor binding 1/195 275/18639 0.00363636363636364 0.34758041958042 0.945729314446157 0.949686340866434 GO:0046982 protein heterodimerization activity 1/195 369/18639 0.002710027100271 0.259036898061288 0.980155337800134 0.982201591114957 GO:0140098 catalytic activity, acting on RNA 1/195 387/18639 0.00258397932816537 0.246988670244484 0.983642380424752 0.983642380424752